CN105748762A - Traditional Chinese medicine preparation for treating hypertensive disease and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for treating hypertensive disease and preparation method thereof Download PDF

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CN105748762A
CN105748762A CN201610185981.0A CN201610185981A CN105748762A CN 105748762 A CN105748762 A CN 105748762A CN 201610185981 A CN201610185981 A CN 201610185981A CN 105748762 A CN105748762 A CN 105748762A
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chinese medicine
decoction
preparation
parts
medicine preparation
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钱林超
江宏
赵玉芹
许丽美
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Xiamen University
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Xiamen University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
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Abstract

The invention provides a traditional Chinese medicine preparation for treating a hypertensive disease and a preparation method thereof, and relates to the field of traditional Chinese medicine, wherein the traditional Chinese medicine preparation for treating the hypertensive disease has the effects of warming yang for resolving fluid retention and soothing the liver and promoting urination and is low in cost and free of any toxic and side effects. The traditional Chinese medicine preparation for treating the hypertensive disease is prepared from, by mass, 9-12 parts of radix bupleuri, 9-30 parts of radix scutellariae, 9-15 parts of cassia twigs, 15-30 parts of poria cocos, 15-30 parts of rhizoma alismatis, 9-18 parts of polyporus umbellatus, 15-30 parts of raw rhizoma atractylodis macrocephalae and 15-30 parts of radix salviae miltiorrhizae. The dosage forms such as decoction, tablets, powder, pills and capsules can be adopted. A corresponding product can be obtained according to a conventional traditional Chinese medicine preparation preparing method after the raw materials are mixed. The decoction is prepared through the steps that the raw materials are mixed, soaked by adding water and then decocted with slow fire, first-time water decoction is taken for standby application, decoction dregs is continuously decocted with the slow fire by adding water, second-time water decoction is taken, the first-time water decoction and the second-time water decoction are mixed, and then the traditional Chinese medicine decoction for treating the hypertensive disease is obtained.

Description

A kind of Chinese medicine preparation of Hypertension and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to Chinese medicine preparation of a kind of Hypertension and preparation method thereof.
Background technology
Hypertension is the class cardiovascular and cerebrovascular disease that human health is arrived in serious threat, easily caused by the target organs such as the heart, brain, blood vessel, kidney infringement (Liu Lisheng. China hypertension prevention and control guide 2010 [J]. China hypertension magazine, 2011,19 (8): 701-743).Research in the past shows, 1,2 grades of hypertension of Chinese medicine have obvious curative effect, some patients can be made to subtract and to stop Western medicine, stabilizing blood pressure and there is advantage (Ma Weihong in hypertension secondary prevention and rehabilitation course, Li Qi, Liu Weiping. aged hypertensives epidemic characteristic and therapy of combining Chinese and Western medicine present Research [J]. China's Chinese medicine magazine, 2011,26 (4): 766-770).Hypertension phlegm-damp heap soil or fertilizer over and around the roots Sheng card is the syndrome (Xiong Xingjiang that essential hypertension is common, king rank. classics recipe Hypertension clinical practice [J]. CHINA JOURNAL OF CHINESE MATERIA MEDICA, 2014,39 (5): 929-933), show as headache, dizziness, nausea and vomiting, chest distress and palpitation symptoms etc. clinically more.In recent years, the dietary habit of people and animation there occurs bigger change, and long-term eating cold and uncooked food excessively melon and fruit, social work excessive pressure are nervous, cause that the morbidity of hypertension becomes younger increasingly, and its pathogeny is also different with tradition.From clinical observation, it is more and the liver failing to maintain the normal flow of QI that fire caused by depression of liver-QI, fluid-retention stagnating in the interior is relevant that hypertension phlegm-damp stops up the Deterioration mechanism containing card.Clinically show themselves in that headache, dizziness, cardiopalmus, sleep poor, irritable, corpulent tongue have greatly tooth print, pulse condition mostly to be heavy to slide or heavy string etc., how treatment makes laws from soothing the liver diuretic more.By soothing the liver scalable feelings will, alleviate stress, alleviate the symptoms such as the agitation caused by pathogenic fire derived from stagnation of liver-QI, disturbing upward of liver-fire, insomnia, headache, dizziness, the phlegm retention that stagnation of QI causing fluid-retention causes can be avoided again to stop gathering simultaneously, diuretic and diuresis, can effectively regulate the water liquid metabolism in human body, diseases caused by retention of fluid turbid damp is made to have dispelled outlet, thus alleviating because of general on fluid-retention stagnating in the interior, diseases caused by retention of fluid or insult the dizziness caused by the heart, cardio palmus shape.This positive so-called " damp eliminating is diuresis not, and Fei Qizhi is also ".
Summary of the invention
Present invention aim at offer and have the soothing the liver diuretic effect of warming yang for resolving fluid retention, expense is low, and the Chinese medicine preparation of a kind of Hypertension without any side effects and preparation method thereof.
The Chinese medicine preparation of described Hypertension consisting of in mass ratio: Radix Bupleuri 9~12, Radix Scutellariae 9~30, Ramulus Cinnamomi 9~15, Poria 15~30, Rhizoma Alismatis 15~30, Polyporus 9~18, Rhizoma Atractylodis Macrocephalae 15~30, Radix Salviae Miltiorrhizae 15~30.
The Chinese medicine preparation of described Hypertension composition in mass ratio is preferably: Radix Bupleuri 9, Radix Scutellariae 18, Ramulus Cinnamomi 12, Poria 18, Rhizoma Alismatis 30, Polyporus 18, Rhizoma Atractylodis Macrocephalae 18, Radix Salviae Miltiorrhizae 18.
The Chinese medicine preparation of described Hypertension can adopt the dosage forms such as decoction, tablet, powder, pill, capsule.
The preparation method of the Chinese medicine preparation of described Hypertension is as follows:
After being mixed by each raw material, Chinese medicine preparation preparation method can obtain corresponding product routinely.
The preparation method of the Chinese medicine decoction of described Hypertension is as follows:
Soak after each raw material is mixed, then with slow fire boiling, take first time decocting liquid standby, then continuation slow fire boiling that medicinal residues are added water, take second time decocting liquid, then by first time decocting liquid and second time decocting liquid mixing, obtain the Chinese medicine decoction of Hypertension.
The described condition soaked can soak 30min for the 900ml that adds water;The time of described slow fire boiling can be 1h;The described amount taking first time decocting liquid can be 250ml;The described condition continuing slow fire boiling that added water by medicinal residues again can be medicinal residues are added water 800ml continue slow fire boiling 1h;The described amount taking second time decocting liquid can be 250ml.
The instructions of taking of the Chinese medicine decoction of described Hypertension can be: point twice decoction being taken warmly of morning and evening, every day 1 dose.Treatment 30d is a course for the treatment of.
Beneficial effects of the present invention:
The present invention is used for Hypertension, and this Chinese prescription has effect of warming yang for resolving fluid retention, soothing the liver diuretic, and medical expense is low, have specially good effect, have no side effect.
Detailed description of the invention
The Chinese medicine preparation of Hypertension consisting of in mass ratio: Radix Bupleuri 9~12, Radix Scutellariae 9~30, Ramulus Cinnamomi 9~15, Poria 15~30, Rhizoma Alismatis 15~30, Polyporus 9~18, Rhizoma Atractylodis Macrocephalae 15~30, Radix Salviae Miltiorrhizae 15~30.After being mixed by each raw material, Chinese medicine preparation preparation method can obtain corresponding product routinely.
Model case:
Medical record one:
Zhang, man, 55 years old.During first visit: tell nearly two weeks and often feel dizzy, feeling of fullness in the head.When examining: feeling of fullness in the head, item does not tightly relax, two temple place pain, and mood is not relaxed or meets labor postemphasis, dynamic then hyperhidrosis, sleeps not good enough, dreaminess, and urine is partially yellow, and stool tune, irascible temperament, left and right arms blood pressure 162/98mmHg, tongue is dark red, yellow and greasy fur, left stringy pulse, right rolling pulse slightly string.
Diagnosis: hypertension.
Dialectical: disturbing upward of liver-fire, drink heat knot mutually.
Method for the treatment of: clearing away heat and promoting diuresis, suppressing the hyperactive liver and subsiding YANG.
Medicine: Radix Bupleuri 9g, Radix Scutellariae 18g, Ramulus Cinnamomi 9g, Poria 15g, Rhizoma Alismatis 15g, Polyporus 9g, Rhizoma Atractylodis Macrocephalae 15g, Radix Salviae Miltiorrhizae 15g.
Doctor's advice avoids pungent food scorching, greasy product, controls the emotion, keeps happy.
Two examine: after 7 doses, all cards slightly subtract, left and right arms blood pressure 152/96mmHg, then enter 7 doses.Three examine: left and right arms blood pressure is down to 146/90mmHg, then with top plus-minus treatment two weeks, blood pressure was stable in 130~140/80~90mmHg.Hereafter treating again two courses for the treatment of (two months) with above-mentioned for main formula, above-mentioned symptom is all alleviated, and blood pressure also controlled in normal range.
Medical record two:
Lee, man, 38 years old, during first visit: readme is dizzy, stiffness of the nape, in the afternoon substantially, on ordinary days drowsiness.Quarter examines: dizzy stiffness of the nape, spiritlessness and weakness, and mouth is dry not bitter, receive can, sleep not good enough, two is just normal.Pale tongue red tape is dark and gloomy, and tongue heel teeth prints, thick, yellow and greasy fur, and left and right arteries and veins closes all heavy string of chi and strong, blood pressure,right arm 150/120mmHg, blood pressure,left arm 146/110mmHg.
Diagnosis: hypertension.
Dialectical: drink heat knot, blood-stasis internal-depression mutually.
Method for the treatment of: clearing away heat and promoting diuresis, suppressing the hyperactive liver is invigorated blood circulation.
Medicine: Radix Bupleuri 10g, Radix Scutellariae 20g, Ramulus Cinnamomi 12g, Poria 24g, Rhizoma Alismatis 24g, Polyporus 12g, Rhizoma Atractylodis Macrocephalae 24g, Radix Salviae Miltiorrhizae 18g.6 doses, every day 1 dose, it is decocted in water for oral dose.Doctor's advice: when clothes temperature medicine.During taking this Chinese medicine, withdraw other drug.Noticing that daily life often has, diet of taking good care of oneself, how plain few meat or fish is, harmonizing emotions.
Two examine, and medicine rear left blood pressure,right arm is all 140/110mmHg, no more side effects.
Three examine, and after continuing to take two weeks by top, left and right arms blood pressure is all 140/96mmHg, not good enough with sleep.Continuing conditioning one month, left and right arms blood pressure stabilization is between 136~140/86~90mmHg.
Medical record three:
Wu, man, 65 years old, during first visit: tell dizziness, cardiopalmus recurrent exerbation more than 2 years.Examining and see: patient's body is partially fat, fear cold, very, after activity, cardiopalmus is easily sent out in dizziness, and limbs are heavy, the soreness of waist, spiritlessness and weakness, time have agitation, nocturia 3~4 times, big loose stool is thin.Having a medical check-up: left and right arms blood pressure 170/100mmHg, double; two lower limb slight depression edema, Sublingual is purple dark, and body of the tongue is light red slightly dark, and tongue Bai Weihou is greasy, and there are indentation, right deep-thready pulse string, left deep-rolling pulse string in the big limit of corpulent tongue.
Diagnosis: hypertension.
Dialectical: deficiency of spleen-YANG and kidneyYANG, fluid-retention stagnating in the interior.
Method for the treatment of: spleen invigorating the kidney warming, activating blood and promoting diuresis.
Medicine: Radix Bupleuri 9g, Radix Scutellariae 9g, Ramulus Cinnamomi 15g, Poria 15g, Rhizoma Alismatis 30g, Polyporus 18g, Rhizoma Atractylodis Macrocephalae 30g, Radix Salviae Miltiorrhizae 30g.It is decocted in water for oral dose, day 1 dose, serve on 7 doses.
Two examine, and dizziness alleviates, and fear cold alleviation, and left and right arms 150/96mmHg edema of pair of lower extremities is inconspicuous, no more side effects, then takes 14 doses.
Three examine, double; two lower limb slight depression edema, left and right arms blood pressure 142/92mmHg, continual cure two months, and left and right arms controlling of blood pressure is in 138~142/82~90mmHg scope, and edema of pair of lower extremities disappears, and all diseases alleviate.

Claims (6)

1. the Chinese medicine preparation of a Hypertension, it is characterised in that its consisting of in mass ratio: Radix Bupleuri 9~12, Radix Scutellariae 9~30, Ramulus Cinnamomi 9~15, Poria 15~30, Rhizoma Alismatis 15~30, Polyporus 9~18, Rhizoma Atractylodis Macrocephalae 15~30, Radix Salviae Miltiorrhizae 15~30.
2. the Chinese medicine preparation of a kind of Hypertension as claimed in claim 1, it is characterised in that its consisting of in mass ratio: Radix Bupleuri 9, Radix Scutellariae 18, Ramulus Cinnamomi 12, Poria 18, Rhizoma Alismatis 30, Polyporus 18, Rhizoma Atractylodis Macrocephalae 18, Radix Salviae Miltiorrhizae 18.
3. the Chinese medicine preparation of a kind of Hypertension as claimed in claim 1, it is characterised in that adopt decoction, tablet, powder, pill, capsule.
4. the preparation method of the Chinese medicine preparation of a kind of Hypertension as claimed in claim 1, it is characterised in that after being mixed by each raw material, Chinese medicine preparation preparation method can obtain corresponding product routinely.
5. the preparation method of decoction as claimed in claim 3, it is characterised in that it specifically comprises the following steps that
Soak after each raw material is mixed, then with slow fire boiling, take first time decocting liquid standby, then continuation slow fire boiling that medicinal residues are added water, take second time decocting liquid, then by first time decocting liquid and second time decocting liquid mixing, obtain the Chinese medicine decoction of Hypertension.
6. the preparation method of as claimed in claim 5 decoction, it is characterised in that described in the condition soaked be the 900ml immersion 30min that adds water;The time of described slow fire boiling is 1h;The described amount taking first time decocting liquid is 250ml;The described condition continuing slow fire boiling that added water by medicinal residues again continues slow fire boiling 1h for medicinal residues add water 800ml;The described amount taking second time decocting liquid is 250ml.
CN201610185981.0A 2016-03-29 2016-03-29 Traditional Chinese medicine preparation for treating hypertensive disease and preparation method thereof Pending CN105748762A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107137542A (en) * 2017-05-25 2017-09-08 浦北县中医医院 A kind of pharmaceutical composition of reducing blood lipid

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104815232A (en) * 2015-05-06 2015-08-05 谢璞 Traditional Chinese medicine preparation for treating primary pulmonary hypertension and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104815232A (en) * 2015-05-06 2015-08-05 谢璞 Traditional Chinese medicine preparation for treating primary pulmonary hypertension and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
邹志东等: "北京地区近10年高血压病中医用药规律分析", 《中国中药杂志》 *
钱林超等: "五苓散抗高血压机理探析", 《世界中医药》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107137542A (en) * 2017-05-25 2017-09-08 浦北县中医医院 A kind of pharmaceutical composition of reducing blood lipid

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