CN105748730A - Medicine for treating idiopathic thrombocytopenic purpura - Google Patents
Medicine for treating idiopathic thrombocytopenic purpura Download PDFInfo
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- CN105748730A CN105748730A CN201410786804.9A CN201410786804A CN105748730A CN 105748730 A CN105748730 A CN 105748730A CN 201410786804 A CN201410786804 A CN 201410786804A CN 105748730 A CN105748730 A CN 105748730A
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Abstract
The invention discloses a medicine for treating idiopathic thrombocytopenic purpura. The medicine is prepared from 12 traditional Chinese medicines including astragalus roots, unprocessed rehmannia roots, white peony roots, prepared rehmannia roots, angelica roots, glossy privet fruits, herba ecliptae, rhizoma atractylodis macrocephalae, Chinese dates, herba agrimoniae, callicarpae macrophyllae folium, and moutan root barks. The medicine comprises, according to a weight ratio, 25-35 parts of astragalus roots, 17-23 parts of unprocessed rehmannia roots, 17-23 parts of white peony roots, 17-23 parts of prepared rehmannia roots, 8-12 parts of angelica roots, 8-12 parts of glossy privet fruits, 8-12 parts of herba ecliptae, 8-12 parts of rhizoma atractylodis macrocephalae, 30-50 parts of Chinese dates, 25-35 parts of herba agrimoniae, 25-35 parts of callicarpae macrophyllae folium, and 8-12 parts of moutan root barks. Clinical verifications show that the medicine has a preferable effect on treating idiopathic thrombocytopenic purpura. It is proved by actual use that that the medicine has characteristics of better therapeutic effect and short course of treatment, is free of side or toxic effect, and has the advantage of low cost of treatment.
Description
Technical field
The present invention relates to a kind of medicine treating idiopathic thrombocytopenic purpura, belong to the technical field of pharmaceuticals for the treatment of idiopathic thrombocytopenic purpura.
Background technology:
Idiopathic thrombocytopenic purpura disease is a kind of common hemorrhage, multiple is born in child and youth, especially with young women for many.Clinical manifestation is petechia and the ecchymosis of skin, even epistaxis, bleeding from the gum, haematemesis or hematuria, have blood in stool.Platelet-free minimizing property this name of disease of purpura in Chinese medicine ancient books and records.The medicine treating this idiopathic thrombocytopenic purpura disease at present is mostly Western medicine, seldom uses Chinese medicine.Although these Western medicine have certain curative effect, but the phenomenon of the toxic and side effects of its existence also ratio is more serious, and Western medicine there is also and treats that the course for the treatment of is longer, take effect slower shortcoming；Additionally, existing Western medicine also ubiquity medical expense higher, and curative effect also less-than-ideal problem.Therefore, the effect of existing treatment idiopathic thrombocytopenic purpura disease medicament or not ideal, still can not meet the treatment needs of patient.
Summary of the invention:
It is an object of the invention to: provide a kind of therapeutic effect better, have no side effect, the medicine for the treatment of idiopathic thrombocytopenic purpura that medical expense is relatively low, to overcome the deficiencies in the prior art.
The present invention is achieved in that
The medicine that the present invention a kind of treats idiopathic thrombocytopenic purpura is, this medicine is by the Radix Astragali, the Radix Rehmanniae, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Fructus Ligustri Lucidi, Herba Ecliptae, the Rhizoma Atractylodis Macrocephalae, Fructus Jujubae, Herba Agrimoniae, Folium Callicarpae Macrophyllae, the Cortex Moutan medicament that totally 12 taste Chinese medicines are made, each taste Chinese medicine proportioning by weight is: the Radix Astragali 25～35 parts, 17～23 parts of the Radix Rehmanniae, the Radix Paeoniae Alba 17～23 parts, 17～23 parts of Radix Rehmanniae Preparata, Radix Angelicae Sinensis 8～12 parts, Fructus Ligustri Lucidi 8～12 parts, Herba Ecliptae 8～12 parts, the Rhizoma Atractylodis Macrocephalae 8～12 parts, 30～50 parts of Fructus Jujubae, Herba Agrimoniae 25～35 parts, Folium Callicarpae Macrophyllae 25～35 parts, Cortex Moutan 8～12 parts.
Above-mentioned each taste Chinese medicine optimum proportioning by weight is: the Radix Astragali 30 parts, 20 parts of the Radix Rehmanniae, the Radix Paeoniae Alba 20 parts, 20 parts of Radix Rehmanniae Preparata, Radix Angelicae Sinensis 10 parts, Fructus Ligustri Lucidi 10 parts, Herba Ecliptae 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 40 parts of Fructus Jujubae, Herba Agrimoniae 30 parts, Folium Callicarpae Macrophyllae 30 parts, Cortex Moutan 10 parts.
Above-mentioned medicament is oral liquid formulation.
In the formula of the present invention, each taste Chinese medicine used has following main feature:
The Radix Astragali: sweet in the mouth slightly warm in nature, returns lung, spleen, liver, kidney channel；Polishing consolidating superficial resistance, holds in the palm skin ulcer granulation promoting.Curing mainly body void spontaneous perspiration, chronic diarrhea, proctoptosis, uterine prolapse, chronic nephritis, body is impractical swollen, chronic ulcer, open sore part disunion of a specified duration.
The Radix Rehmanniae: sweet-bitter flavor, cold in nature and enter blood system, clearing away heat and cooling blood；Curing mainly fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon hinders constipation.
The Radix Paeoniae Alba: the Radix Paeoniae Alba has effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant.
Radix Rehmanniae Preparata: Radix Rehmanniae Preparata sweet in the mouth tepor matter is moistened, YIN nourishing of both having enriched blood again can vital essence replenishing and marrow benifiting.
Radix Angelicae Sinensis: Radix Angelicae Sinensis sweet in the mouth and weigh, can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, invigorating middle warmer has, row in have benefit, for the key medicine in blood.
Fructus Ligustri Lucidi: Fructus Ligustri Lucidi has the effect mending waist knee joint, strengthening bone and muscle, reinforcing YIN-essence kidney.
Herba Ecliptae: Herba Ecliptae is the herb of dicotyledon medicine feverfew Eclipta prostrata, the prescription name of Herba Ecliptae is named again Herba Ecliptae, Herba Ecliptae has nourishing the liver and kidney, crow palpus teeth consolidating, effect of cooling blood for hemostasis, cures mainly deficiency of the liver and kindey, blurring of vision, soreness of the waist and knees, vertigo and tinnitus, the diseases such as luxated tooth of turning white typically by Herba Ecliptae.
The Rhizoma Atractylodis Macrocephalae: the Rhizoma Atractylodis Macrocephalae has air making-up and spleen enlivening, dampness diuretic, hidroschesis, antiabortive effect.
Fructus Jujubae: Fructus Jujubae sweet in the mouth is warm in nature, taste warp, has invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, relaxes the function of the property of medicine.Modern pharmacological research is existing, and Fructus Jujubae can make oxygen content in blood strengthen, nourish systemic cell, is the analeptic of a kind of drug effect mitigation.
Herba Agrimoniae: Herba Agrimoniae has effect of astringing to arrest bleeding, detoxification sore treatment, parasite killing, puckery antiperspirant, cough-relieving.It is usually used in the diseases such as spitting of blood, haematemesis, epistaxis, hematuria, metrorrhagia, dysentery, malaria, diabetes hyperhidrosis, overstrain cough.
Folium Callicarpae Macrophyllae: the another name of Folium Callicarpae Macrophyllae has false great Ai, bones of the dead wind, big blade, carries on the back wood, thin Piao Mu, sheep ear, Folium Callicarpae Formosanae etc. in vain, and for root or the leaf of dicotyledon medicine Verbenaceae Folium Callicarpae Macrophyllae, nature and flavor are arduous, flat；GUIXIN, lung meridian；There is effect of dissipating blood stasis hemostasis, reducing swelling and alleviating pain.
Cortex Moutan: the another name of Cortex Moutan has Cortex Moutan, unpeeled CORTEX MOUTAN, wood Radix Paeoniae, bar Cortex Moutan, Luoyang flower, moutan root bark, DANGEN etc.；Its acrid in the mouth is bitter, cool in nature；GUIXIN, liver, kidney, lung meridian；There is effect of heat clearing away, promoting blood circulation to remove blood stasis.
The present invention is according to Conventional wisdom, and in conjunction with the pathomechanism of modern Chinese medicine and western medicine, it is believed that idiopathic thrombocytopenic purpura disease is many owing to depressed rage impairing the liver, temper are weak or QI and blood is lost the factor such as pole, internal organs damage and become.Therefore the present invention is directed to the feature of idiopathic thrombocytopenic purpura disease, through long-felt, test, compare and study, by above-mentioned conventional inexpensive and after proving the formula that safer Chinese medicine carries out reasonable science through clinical usage, make each taste Chinese medicine can mutually coordinated common performance its based on blood yiqi, benefit heart spleen invigorating be auxiliary drug effect.According to clinical verification, the present invention has the effect treating idiopathic thrombocytopenic purpura disease preferably.Through actually used proof, the present invention compared with existing medicine, the present invention not only have therapeutic effect better, the feature of short treating period, but also have have no side effect, advantage that medical expense is low.
Detailed description of the invention:
Embodiments of the invention: take the Radix Astragali 30 grams, 20 grams of the Radix Rehmanniae, the Radix Paeoniae Alba 20 grams, 20 grams of Radix Rehmanniae Preparata, Radix Angelicae Sinensis 10 grams, Fructus Ligustri Lucidi 10 grams, Herba Ecliptae 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, 40 grams of Fructus Jujubae, Herba Agrimoniae 30 grams, Folium Callicarpae Macrophyllae 30 grams, 10 gram of 12 taste Chinese medicine of Cortex Moutan are raw material, after first soaking 20～30 minutes with 300～400 milliliters of water after being mixed by each raw material, decoct the mixture obtaining medicinal liquid and raw material for 10～15 minutes after being boiled again, after being leached by medicinal liquid, obtain the medicinal liquid of first time decoction；Add 300～400 milliliters of water in raw material, 10～15 minutes medicinal liquid and raw material medicinal residues mixture again are decocted again after being boiled, obtain the medicinal liquid that second time decocts after being leached by medicinal liquid, after the medicinal liquid mixing that the medicinal liquid that will decoct first time and second time decoct, can be prepared by the oral liquid formulations of the present invention.
The instructions about how to take medicine of the oral liquid formulations of the present invention are: every day 2 times, each 80～100 milliliters, within general 1 month, are a course for the treatment of.
The clinical observation example that adopt the present invention treat idiopathic thrombocytopenic purpura is presented herein below, is further described with the curative effect to the present invention.
Patient female, 23 years old, be idiopathic thrombocytopenic purpura disease through examination in hospital diagnosis, and the laboratory values before treatment is: platelet 40000/ cubic millimeter, 6 minutes bleeding times, clotting time 5 minutes, erythrocyte 380,000/cubic millimeter, 7.5 grams of % of hemoglobin；Total white blood cells 5000/ cubic millimeter.
Chemically examining check after taking the present invention 3 months is that platelet 210000/ cubic millimeter, in 3 minutes bleeding times, clotting time 2 minutes, three indexes have recovered normal, and old purpura substantially eliminates, has no and newly goes out purpura.Patient has rosy cheeks, hale and hearty.Patient no longer takes medicine.
Taking during the present invention treats, there is not any untoward reaction and toxic and side effects in patient.
Claims (3)
1. the medicine treating idiopathic thrombocytopenic purpura, it is characterized in that: this medicine is by the Radix Astragali, the Radix Rehmanniae, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Fructus Ligustri Lucidi, Herba Ecliptae, the Rhizoma Atractylodis Macrocephalae, Fructus Jujubae, Herba Agrimoniae, Folium Callicarpae Macrophyllae, the medicament that Cortex Moutan 12 taste Chinese medicine is made, each taste Chinese medicine proportioning by weight is: the Radix Astragali 25～35 parts, 17～23 parts of the Radix Rehmanniae, the Radix Paeoniae Alba 17～23 parts, 17～23 parts of Radix Rehmanniae Preparata, Radix Angelicae Sinensis 8～12 parts, Fructus Ligustri Lucidi 8～12 parts, Herba Ecliptae 8～12 parts, the Rhizoma Atractylodis Macrocephalae 8～12 parts, 30～50 parts of Fructus Jujubae, Herba Agrimoniae 25～35 parts, Folium Callicarpae Macrophyllae 25～35 parts, Cortex Moutan 8～12 parts.
2. the medicine for the treatment of idiopathic thrombocytopenic purpura according to claim 1, it is characterised in that: each taste Chinese medicine proportioning by weight is: the Radix Astragali 30 parts, 20 parts of the Radix Rehmanniae, the Radix Paeoniae Alba 20 parts, 20 parts of Radix Rehmanniae Preparata, Radix Angelicae Sinensis 10 parts, Fructus Ligustri Lucidi 10 parts, Herba Ecliptae 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 40 parts of Fructus Jujubae, Herba Agrimoniae 30 parts, Folium Callicarpae Macrophyllae 30 parts, Cortex Moutan 10 parts.
3. the medicine for the treatment of idiopathic thrombocytopenic purpura according to claim 1, it is characterised in that: described medicament is oral liquid formulation.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108126058A (en) * | 2018-01-18 | 2018-06-08 | 淳安县汾口镇强身食品商行 | A kind of Chinese medicine composition for treating purpura and its preparation method and application |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101313953A (en) * | 2008-07-22 | 2008-12-03 | 上海中医药大学附属岳阳中西医结合医院 | Medicament composition for treating idiopathic thromboeytopenic purpura and preparation method thereof |
| CN103505679A (en) * | 2013-08-30 | 2014-01-15 | 杜丽娟 | Drug for treating blood diseases, preparation method, and applications thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101313953A (en) * | 2008-07-22 | 2008-12-03 | 上海中医药大学附属岳阳中西医结合医院 | Medicament composition for treating idiopathic thromboeytopenic purpura and preparation method thereof |
| CN103505679A (en) * | 2013-08-30 | 2014-01-15 | 杜丽娟 | Drug for treating blood diseases, preparation method, and applications thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108126058A (en) * | 2018-01-18 | 2018-06-08 | 淳安县汾口镇强身食品商行 | A kind of Chinese medicine composition for treating purpura and its preparation method and application |
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Application publication date: 20160713 |