CN105727382B - A kind of continous way CRRT machine capability bascules of two tripper - Google Patents
A kind of continous way CRRT machine capability bascules of two tripper Download PDFInfo
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- CN105727382B CN105727382B CN201610059232.3A CN201610059232A CN105727382B CN 105727382 B CN105727382 B CN 105727382B CN 201610059232 A CN201610059232 A CN 201610059232A CN 105727382 B CN105727382 B CN 105727382B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
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Abstract
A kind of continous way CRRT machine capability bascules of two tripper, including the blood circulation system by entering blood vessel road, blood pump, hollow fiber dialyzer, blood back pipeline form；The first fluid circulation system being made up of drain pipe road, liquid pump, displacement liquid/dialysis fluid container, hollow fiber dialyzer, liquid back pipe road, displacement liquid/dialysis fluid container have two.Increase the second liquid circulatory system being made up of exogenous displacement liquid/dialysis fluid container, exogenous displacement liquid/dialysis fluid container drain pipe road, tripper, liquid pump, displacement liquid/dialysis fluid container, exogenous displacement liquid/dialysis fluid container liquid back pipe road.First fluid circulation system contacts with blood circulation system carries out mass exchange, and because its volume is fixed, volume change is not related in exchange process.The second liquid circulatory system changes two liquid/dialysis fluid container and carries out fluid exchange in turn, is allowed to refill clean fresh displacement liquid, realizes and solute purpose is constantly removed under mobile environment.
Description
Technical field
The invention belongs to continuous blood purification device, the continous way CRRT machines of specifically a kind of two tripper
Capacity balancing device.
Background technology
The English of CRRT (i.e. continuous renal replacement therapy) continuous renal replacement therapy
Abbreviation.Also known as CBP (continuous blood purification)；Bedside hemo-filtration.It is to use daily 24 hours or connect
A kind of long-time of nearly 24 hours, continuous extracorporeal blood purify therapy to substitute impaired renal function.
Nineteen ninety-five, in the international CRRT academic conferences of the first that San Diego, USA is held, CRRT is by formal definition：
It is all can continuity remove solute, and to organ function rise supporting function blood purification technology.The World War II phase
Between, Canadian Murray and Delmore succeed in developing First artificial kidney machine, and are used for clinical treatment renal failure in l946
Exhaust, later blood purification technology is rapidly developed.Blood purification is that blood samples of patients is led to external and filled by one kind purification
Put, remove the purpose that some of which morbid substance purification blood reaches treatment disease.It mainly includes haemodialysis, blood is filtered
Cross, hemodiafiltration, blood perfusion, plasma exchange, immuno absorbence etc..Blood purification therapy is not provided purely for treating at present
Acute and chronic patients with renal failure, also it has been widely applied in the rescue of Severe acute disease patient.
CRRT clinical practice targets are to remove internal excess moisture, remove internal metabolic waste, poisonous substance, correct Water-Electrolyte
It is disorderly, it is ensured that nutritional support, to promote graft function and remove various cell factors, inflammatory mediator.It can be used for：Various angiocarpy
Acute and chronic renal failure functional lability, Metabolism or with encephaledema, and Multiple Organ Dysfunction Syndrome, it is acute
Respiratory Distress Syndrome(RDS), crush syndrome, acute necrotic pancreatitis, chronic heart failure, hepatic encephalopathy, medicine and toxic poisoning etc.
Treatment.
At present, the CRRT machines clinically produced mostly using German Bei Lang companies, or the life of German Fresenius group
The CRRT machines of production, or the CRRT machines of some other brand carry out Continuous Renal Replace Threapy.
CRRT machines in the course of the work, it is necessary to accurately control disengaging cardiopulmonary bypass in patients liquid speed and amount, disengaging
The difference of amount of liquid is net ultrafiltration, i.e., from the moisture content removed in vivo.Usual CRRT machines are controlled by displacement liquid/dialysis liquid pump
Into the liquid velocity of extracorporal circulatory system, the speed of extracorporal circulatory system liquid is controlled out by waste drains pump, while also passes through CRRT machines
Scale inside device carrys out the amount of accurate dynamic measurement disengaging liquid, and feedback regulation displacement liquid/dialyzate, waste liquid pump speed reach
To the purpose of control disengaging extracorporal circulatory system amount of liquid.
It will be apparent that control disengaging fluid balance existing defects by way of scale dynamic measurement liquid weight：First, scale needs
Often calibration, precision can be also gradually reduced during use, second, scale measurement can only be carried out in inactive state, it is right in therapeutic process
The collision of machine can cause scale not work, therefore existing CRRT machines can not work in mobile environment.
Weighed to overcome using scale, the defects of CRRT machines can not be used in mobile environment, someone's research uses flow
The method of monitoring dynamically determines to realize the volume controlled of CRRT machines and flows into, flows out extracorporal circulatory system flow rate of liquid simultaneously basis
Sectional area calculates outflow.The method of dynamic measurement flow velocity includes magnetic current method and ultrasonic method.Although this method can avoid scale
The defects of can not being worked under mobile condition, but the defects of precision is inadequate, and error is big still be present.Instant flow measurement needs the several seconds
A flow is measured, need to be measured tens times in one minute, then each measurement result is added up and obtains the liquid in the unit interval
Amount.Even if therefore single measurement error very little, but the additive effect of measuring result error necessarily causes overall error very big many times.
It is that direct measurement obtains some period every time although also dynamic measures scale system for instant flow measurement
Interior total liquid output, rather than by the cumulative of multiple measurement results, therefore additive effect is not present.It is in addition, micro- in liquid
The change of minute bubbles and pipe section product in use can all influence flow measurement precision.
For CRRT treatments, daily fluid exchange amount reaches as high as more than 100L, such as error typically in more than 20L
Within 1%, the liquid margin of error is 200ml-1000ml, if the treatment absolute error amount of continuous a few days is bigger.And flowmeter
Control capability balance error is difficult to reach less than 1%.
Existing CRRT machines can not be useful in progress CRRT in the Moveable type vehicles such as aircraft, automobile, train, steamer and control
Treat, this is just to being badly in need of CRRT treatments, and due to the limitation in distance and the vehicles, can not carry out CRRT treatments and bring to choose
War, such as the injured soldier in battlefield can only transport medical base rescue and treatment back, and patient with severe symptoms can not rob ambulance is enterprising
Rescue and treat.
Therefore CRRT machines need more convenient use, more accurate capacity control device and system.
The content of the invention
In order to solve the above-mentioned technical problem, the present invention proposes a kind of continous way CRRT machine capabilities balance of two tripper
Device, including the blood circulation system by entering blood vessel road, blood pump, hollow fiber dialyzer, blood back pipeline form, by drain pipe
Road, liquid pump, displacement liquid/dialysis fluid container, hollow fiber dialyzer, the first fluid circulation system of liquid back pipe road composition.
Blood circulation system and the first fluid circulation system use common hollow fiber dialyzer, in blood circulation system
Blood and the first fluid circulation system in displacement liquid/dialyzate pass through common hollow fiber dialyzer and carry out solute friendship
Change.
Hollow fiber dialyzer includes blood inlet, blood outlet, displacement liquid/dialyzate exports, displacement liquid/dialyzate enters
Mouthful, displacement liquid/dialyzate outlet, displacement liquid/dialyzate entrance are commonly referred to as hollow fiber dialyzer fluid port.；
It is described enter blood vessel road one end introduce patient vessel after, hollow fiber dialyzer is coupled through the other end by blood pump
Blood inlet, the blood outlet of one end connection hollow fiber dialyzer of the blood back pipeline, the other end is by blood recovery patient
In vivo.
Displacement liquid/dialysis fluid container in first fluid circulation system has two, is that the first displacement liquid/dialyzate holds
Device, the second displacement liquid/dialysis fluid container.
One end connection hollow fiber dialyzer fluid port on the drain pipe road, by being divided into two-way after liquid pump, one
Road is by coupling the first displacement liquid/dialysis fluid container after the first tripper, another way is by coupling after the second tripper
Two displacement liquids/dialysis fluid container.
One end connection hollow fiber dialyzer fluid port on the liquid back pipe road enters blood vessel road, and the other end is divided into two
Road, all the way by coupling the first displacement liquid/dialysis fluid container after the first tripper, another way after the second tripper by joining
Connect the second displacement liquid/dialysis fluid container.
Also include by exogenous displacement liquid/dialysis fluid container, exogenous displacement liquid/dialysis fluid container drain pipe road, liquid
The second liquid of pump, tripper, displacement liquid/dialysis fluid container, exogenous displacement liquid/dialysis fluid container liquid back pipe road composition follows
Loop system.
The exogenous displacement liquid/dialysis fluid container drain pipe road one end couples exogenous displacement liquid/dialysis fluid container, separately
One end is divided into two-way after liquid pump, all the way by coupling the second displacement liquid/dialysis fluid container, another way after the first tripper
By coupling the first displacement liquid/dialysis fluid container after the second tripper.
The exogenous displacement liquid/dialysis fluid container liquid back pipe road one end couples exogenous displacement liquid/dialysis fluid container, separately
One end is divided into two-way, and all the way by coupling the second displacement liquid/dialysis fluid container after the first tripper, another way is broken by second
Couple the first displacement liquid/dialysis fluid container after the device of road.
First tripper, the second tripper are coordinated signals, when the first tripper is opened, the second open circuit
Device closes automatically, when the first tripper closes, the second tripper it is automatically open-minded.
The ultrafiltration system being made up of ultrafiltration pipeline, ultrafiltrate pump, ultrafiltration container is additionally provided with the front end on drain pipe road.
The ultrafiltration system also includes flow-monitoring device, and the flow-monitoring device is arranged on ultrafiltration pipeline, to super
Flow rate of liquid and flow in chimney filter road are monitored.
First tripper, the second tripper are tubing clamp.
Displacement liquid/dialysis fluid container can also be with two cavitys being isolated from each other on a device.
First tripper can also be tripper group, each tripper respectively to drain pipe road, liquid back pipe road,
Exogenous displacement liquid/dialysis fluid container drain pipe road, exogenous displacement liquid/dialysis fluid container liquid back pipe road carry out coordinated signals；
Second tripper can also be tripper group, each tripper respectively to drain pipe road, liquid back pipe road,
Exogenous displacement liquid/dialysis fluid container drain pipe road, exogenous displacement liquid/dialysis fluid container liquid back pipe road carry out coordinated signals.
It is 100-500ml that first fluid circulation system, which exchanges volume,.
First tripper, the second tripper are provided with fault alarm.
Flow monitor is additionally provided with the drain pipe road or liquid back pipe road.
Displacement liquid/dialysis fluid container in first fluid circulation system can also be set to more than 2.
Beneficial effect：
The continous way CRRT machine capabilities bascule of two trippers of the invention fixes liquid system using enclosed positive displacement
System carries out solute exchange, and guaranteed capacity is unchanged, reaches saturation or during close to saturation when exchanging liquid, by exogenous displacement liquid/
Dialyzate is regenerated, and to ensure to continue Solute removal ability, efficiently solving existing CRRT machines can not be in mobile environment
The problem of use.Meanwhile the present invention devises two displacement liquid/dialysis fluid containers, when the first displacement liquid/dialysis fluid container connection
When first fluid circulation system is treated, the second displacement liquid/dialysis fluid container connection second liquid circulatory system swaps
And regeneration；When the second displacement liquid/dialysis fluid container, which couples the first fluid circulation system, is treated, the first displacement liquid/dialysis
The liquid container connection second liquid circulatory system is swapped and regenerated；Thus achieve the movement treatment of mobile environment continuity from below.
The continous way CRRT machine capability bascules of two trippers of the invention can be widely applied under mobile environment connect
It is continuous arteriovenous blood filtering (CAVH), failure by CVVH (CVVH), continuous slowly ultrafiltration (SCUF), continuous dynamic
Venous blood dialysis (CAVHD), Continuous Veno-venous haemodialysis (CVVHD), continuous arteriovenous hemodiafiltration
(CAVHDF), Continuous Veno-venous hemodiafiltration (CVVHDF).
Brief description of the drawings
Fig. 1 is dilution filtration mode configuration schematic diagram after continous way CRRT machine capability bascules；
Fig. 2 is dilution filtration mode configuration schematic diagram after the band ultrafiltration of continous way CRRT machine capabilities bascule；
Fig. 3 is dilution filtration mode configuration schematic diagram before continous way CRRT machine capability bascules；
Fig. 4 is dilution filtration mode configuration schematic diagram before the band ultrafiltration of continous way CRRT machine capabilities bascule；
Fig. 5 is continous way CRRT machine capability bascule dialysis mode structural representations；
Fig. 6 is continous way CRRT machine capabilities bascule band ultrafiltration dialysis mode configuration schematic diagram；
Fig. 7 is hollow fiber dialyzer structural representation；
Wherein：Enter blood vessel road 1, blood pump 2, hollow fiber dialyzer 3, blood back pipeline 4, drain pipe road 5, liquid pump 6, displacement
Liquid/dialysis fluid container 7, liquid back pipe road 8, blood inlet 9-1, blood outlet 9-2, displacement liquid/dialyzate outlet 10, displacement liquid/
Dialyzate entrance 11, the first tripper 12-1, the second tripper 12-2, exogenous displacement liquid/dialysis fluid container 13, external source
Property displacement liquid/dialysis fluid container drain pipe road 14,
Exogenous displacement liquid/dialysis fluid container liquid back pipe road 15, ultrafiltration pipeline 16, ultrafiltrate pump 17, ultrafiltration container 18.
Embodiment
Embodiment 1：As shown in figs. 1-7, the continous way CRRT machine capability bascules of a kind of two tripper, including by
Enter blood vessel road 1, blood pump 2, hollow fiber dialyzer 3, the blood circulation system of the composition of blood back pipeline 4, by drain pipe road 5, liquid
The first fluid circulation system that pump 6, displacement liquid/dialysis fluid container 7, hollow fiber dialyzer 3, liquid back pipe road 8 form；
Blood circulation system and the first fluid circulation system use common hollow fiber dialyzer 3, blood circulation system
In blood and the first fluid circulation system in displacement liquid/dialyzate pass through common hollow fiber dialyzer 3 and carry out solute
Exchange；
Hollow fiber dialyzer 3 includes blood inlet 9-1, blood outlet 9-2, displacement liquid/dialyzate outlet 10, displacement
Liquid/dialyzate entrance 11, displacement liquid/dialyzate outlet 10, displacement liquid/dialyzate entrance 11 are commonly referred to as hollow fiber dialyzer liquid
Body end mouth；
It is described enter blood vessel road 1 one end introduce patient vessel after, by blood pump 2 through the other end couple hollow fiber dialyzer
3 blood inlet 9-1, the blood outlet 9-2 of one end connection hollow fiber dialyzer 3 of the blood back pipeline 4, the other end is by blood
Liquid feeds back patient's body；
Displacement liquid/dialysis fluid container 7 in first fluid circulation system has two, is the first displacement liquid/dialyzate
Container 7-1, the second displacement liquid/dialysis fluid container 7-2；
One end connection hollow fiber dialyzer fluid port on the drain pipe road 5, the other end after liquid pump 6 by being divided into
Two-way, all the way by coupling the first displacement liquid/dialysis fluid container 7-1 after the first tripper 12-1, another way is broken by second
Couple the second displacement liquid/dialysis fluid container 7-2 after the device 12-2 of road；
One end connection hollow fiber dialyzer fluid port on the liquid back pipe road 8 enters blood vessel road 1, and the other end is divided into two
Road, all the way by coupling the first displacement liquid/dialysis fluid container 7-1 after the first tripper 12-1, another way passes through the second open circuit
Couple the second displacement liquid/dialysis fluid container 7-2 after device 12-2；
Also include by exogenous displacement liquid/dialysis fluid container 13, exogenous displacement liquid/dialysis fluid container drain pipe road 14,
Liquid pump 6, tripper 12-1,12-2, displacement liquid/dialysis fluid container 7, exogenous displacement liquid/dialysis fluid container liquid back pipe road
The second liquid circulatory system of 15 compositions；
The exogenous displacement liquid/one end of dialysis fluid container drain pipe road 14 couples exogenous displacement liquid/dialysis fluid container
13, the other end is divided into two-way after liquid pump 6, all the way by coupling the second displacement liquid/dialyzate after the first tripper 12-1
Container 7-2, another way after the second tripper 12-2 by coupling the first displacement liquid/dialysis fluid container 7-1；
The exogenous displacement liquid/one end of dialysis fluid container liquid back pipe road 15 couples exogenous displacement liquid/dialysis fluid container
13, the other end is divided into two-way, another all the way by coupling the second displacement liquid/dialysis fluid container 7-2 after the first tripper 12-1
Road after the second tripper 12-2 by coupling the first displacement liquid/dialysis fluid container 7-1；
The first tripper 12-1, the second tripper 12-2 are coordinated signals, when the first tripper 12-1 is opened
When logical, the second tripper 12-2 close automatically, when the first tripper 12-1 is closed, the second tripper 12-2 opens automatically
It is logical.
The ultrafiltration system being made up of ultrafiltration pipeline 16, ultrafiltrate pump 17, ultrafiltration container 18 is additionally provided with the front end on drain pipe road 5
System.
The ultrafiltration system also includes flow-monitoring device, and the flow-monitoring device is arranged on ultrafiltration pipeline 16, right
Flow rate of liquid and flow in ultrafiltration pipeline 16 are monitored.
The first tripper 12-1, the second tripper 12-2 are tubing clamp.
Displacement liquid/dialysis fluid container 7 can also be with two cavitys being isolated from each other on a device.
The first tripper 12-1 can also be the tripper group being made up of single or multiple trippers, each disconnected
Road device is respectively to drain pipe road 5, liquid back pipe road 8, exogenous displacement liquid/dialysis fluid container drain pipe road 14, exogenous displacement
Liquid/dialysis fluid container liquid back pipe road 15 carries out coordinated signals；
The second tripper 12-2 can also be the tripper group of single or multiple trippers composition, each open circuit
Device respectively to drain pipe road 5, liquid back pipe road 8, exogenous displacement liquid/dialysis fluid container drain pipe road 14, exogenous displacement liquid/
Dialysis fluid container liquid back pipe road 15 carries out coordinated signals.
It is 100-500ml that first fluid circulation system, which exchanges volume,.
The first tripper 12-1, the second tripper 12-2 are provided with fault alarm.
Flow monitor is additionally provided with the drain pipe road 5 or liquid back pipe road 8.
Displacement liquid/dialysis fluid container 7 in first fluid circulation system can also be set to more than 2.
Embodiment 2：As shown in Fig. 1,2,7, dilution filtration mode configuration after being, when to filter pattern, displacement liquid/dialysis
Liquid container commonly referred to as replaces liquid container；Exogenous displacement liquid/dialysis fluid container is commonly referred to as exogenous displacement liquid container, displacement
Liquid and dialyzate are identical liquid, and the container for containing the liquid is also identical container.The call that container respectively forms component relates to
And to " displacement ", " dialysis " two word, according to the difference of Therapeutic mode, select " displacement " call different from " dialysis ".
A kind of continous way CRRT machine capability bascules of two tripper, including by entering blood vessel road 1, blood pump 2, hollow
The blood circulation system that fiber dialysis device 3, blood back pipeline 4 form, by drain pipe road 5, liquid pump 6, replace liquid container 7, hollow
The first fluid circulation system that fiber dialysis device 3, liquid back pipe road 8 form；
Blood circulation system and the first fluid circulation system use common hollow fiber dialyzer 3, blood circulation system
In blood and the displacement liquid in the first fluid circulation system solute carried out by common hollow fiber dialyzer 3 exchanged；
Hollow fiber dialyzer 3 includes blood inlet 9-1, blood outlet 9-2, displacement liquid outlet 10, displacement liquid entrance 11,
Displacement liquid outlet 10, displacement liquid entrance 11 are commonly referred to as hollow fiber dialyzer fluid port；
It is described enter blood vessel road 1 one end introduce patient vessel after, by blood pump 2 through the other end couple hollow fiber dialyzer
3 blood inlet 9-1, the blood outlet 9-2 of one end connection hollow fiber dialyzer 3 of the blood back pipeline 4, the other end is by blood
Liquid feeds back patient's body；
Displacement liquid container 7 in first fluid circulation system has two, is put for the first displacement liquid container 7-1, second
Change liquid container 7-2；
The displacement liquid outlet 10 of one end connection hollow fiber dialyzer 3 on the drain pipe road 5, the other end passes through liquid pump
It is divided into two-way after 6, all the way by coupling the first displacement liquid container 7-1 after the first tripper 12-1, another way is broken by second
The displacement liquid container of connection second 7-2 after the device 12-2 of road；
The one end on the drain pipe road 5 can couple the displacement liquid outlet 10 of hollow fiber dialyzer 3, can also couple and put
Change liquid entrance 11；If the displacement liquid outlet 10 of one end connection hollow fiber dialyzer 3 on the drain pipe road 5, hollow fibre
The displacement liquid entrance 11 of dialyzer 3 seals；If the displacement liquid of one end connection hollow fiber dialyzer 3 on the drain pipe road 5 enters
The sealing of displacement liquid outlet 10 of mouth 11, then hollow fiber dialyzer 3；
The one end on the liquid back pipe road 8 couples into blood vessel road 1, and the other end is divided into two-way, passes through the first tripper all the way
The displacement of connection first liquid container 7-1 after 12-1, another way is by coupling the second displacement liquid container 7- after the second tripper 12-2
2；
Also include being filled by exogenous displacement liquid container 13, exogenous displacement liquid container drain pipe road 14, liquid pump 6, open circuit
Put 12-1,12-2, displacement liquid container 7, the second liquid circulatory system of the exogenous composition of displacement liquid container liquid back pipe road 15；
The exogenous displacement liquid container 13 of one end connection of exogenous displacement liquid container drain pipe road 14, the other end is through liquid
It is divided into two-way after pump 6, all the way by coupling the second displacement liquid container 7-2 after the first tripper 12-1, another way passes through second
The displacement liquid container of connection first 7-1 after tripper 12-2；
The exogenous displacement liquid container 13 of one end connection of exogenous displacement liquid container liquid back pipe road 15, the other end is divided into two
Road, all the way by coupling the second displacement liquid container 7-2 after the first tripper 12-1, another way passes through the second tripper 12-2
The displacement liquid container of connection first 7-1 afterwards；
The first tripper 12-1, the second tripper 12-2 are coordinated signals, when the first tripper 12-1 is opened
When logical, the second tripper 12-2 close automatically, when the first tripper 12-1 is closed, the second tripper 12-2 opens automatically
It is logical.
It is made up of as shown in Fig. 2 being additionally provided with the front end on drain pipe road 5 ultrafiltration pipeline 16, ultrafiltrate pump 17, ultrafiltration container 18
Ultrafiltration system.
The ultrafiltration system also includes flow-monitoring device, and the flow-monitoring device is arranged on ultrafiltration pipeline 16, right
Flow rate of liquid and flow in ultrafiltration pipeline 16 are monitored.
The first tripper 12-1, the second tripper 12-2 are tubing clamp.
It can also be with two cavitys being isolated from each other on a device to replace liquid container 7.
The first tripper 12-1 can also be the tripper group being made up of single or multiple trippers, each disconnected
Road device returns to drain pipe road 5, liquid back pipe road 8, exogenous displacement liquid container drain pipe road 14, exogenous displacement liquid container respectively
Liquid pipeline 15 carries out coordinated signals；
The second tripper 12-2 can also be the tripper group of single or multiple trippers composition, each open circuit
Device returns liquid to drain pipe road 5, liquid back pipe road 8, exogenous displacement liquid container drain pipe road 14, exogenous displacement liquid container respectively
Pipeline 15 carries out coordinated signals.
It is 100-500ml that first fluid circulation system, which exchanges volume,.
The first tripper 12-1, the second tripper 12-2 are provided with fault alarm.
Flow monitor is additionally provided with the drain pipe road 5 or liquid back pipe road 8.
Displacement liquid container 7 in first fluid circulation system can also be set to more than 2.
Embodiment 3：As shown in Fig. 3,4,7, mode configuration is filtered for preceding dilution, when to filter pattern, displacement liquid/dialysis
Liquid container commonly referred to as replaces liquid container；Exogenous displacement liquid/dialysis fluid container is commonly referred to as exogenous displacement liquid container, displacement
Liquid and dialyzate are identical liquid, and the container for containing the liquid is also identical container.The call that container respectively forms component relates to
And to " displacement ", " dialysis " two word, according to the difference of Therapeutic mode, select " displacement " call different from " dialysis ".
A kind of continous way CRRT machine capability bascules of two tripper, including by entering blood vessel road 1, blood pump 2, hollow
The blood circulation system that fiber dialysis device 3, blood back pipeline 4 form, by drain pipe road 5, liquid pump 6, replace liquid container 7, hollow
The first fluid circulation system that fiber dialysis device 3, liquid back pipe road 8 form；
Blood circulation system and the first fluid circulation system use common hollow fiber dialyzer 3, blood circulation system
In blood and the displacement liquid in the first fluid circulation system solute carried out by common hollow fiber dialyzer 3 exchanged；
Hollow fiber dialyzer 3 includes blood inlet 9-1, blood outlet 9-2, displacement liquid outlet 10, displacement liquid entrance 11,
Displacement liquid outlet 10, displacement liquid entrance 11 are commonly referred to as hollow fiber dialyzer fluid port；
It is described enter blood vessel road 1 one end introduce patient vessel after, by blood pump 2 through the other end couple hollow fiber dialyzer
3 blood inlet 9-1, the blood outlet 9-2 of one end connection hollow fiber dialyzer 3 of the blood back pipeline 4, the other end is by blood
Liquid feeds back patient's body；
Displacement liquid container 7 in first fluid circulation system has two, is put for the first displacement liquid container 7-1, second
Change liquid container 7-2.
The displacement liquid outlet 10 of one end connection hollow fiber dialyzer 3 on the drain pipe road 5, the other end passes through liquid pump
It is divided into two-way after 6, all the way by coupling the first displacement liquid container 7-1 after the first tripper 12-1, another way is broken by second
The displacement liquid container of connection second 7-2 after the device 12-2 of road；
The one end on the drain pipe road 5 can couple the displacement liquid outlet 10 of hollow fiber dialyzer 3, can also couple and put
Change liquid entrance 11；If the displacement liquid outlet 10 of one end connection hollow fiber dialyzer 3 on the drain pipe road 5, hollow fibre
The displacement liquid entrance 11 of dialyzer 3 seals；If the displacement liquid of one end connection hollow fiber dialyzer 3 on the drain pipe road 5 enters
The sealing of displacement liquid outlet 10 of mouth 11, then hollow fiber dialyzer 3.
The one end on the liquid back pipe road 8 couples into blood vessel road 1, and the other end is divided into two-way, passes through the first tripper all the way
The displacement of connection first liquid container 7-1 after 12-1, another way is by coupling the second displacement liquid container 7- after the second tripper 12-2
2；
Also include being filled by exogenous displacement liquid container 13, exogenous displacement liquid container drain pipe road 14, liquid pump 6, open circuit
Put 12-1,12-2, displacement liquid container 7, the second liquid circulatory system of the exogenous composition of displacement liquid container liquid back pipe road 15；
The exogenous displacement liquid container 13 of one end connection of exogenous displacement liquid container drain pipe road 14, the other end is through liquid
It is divided into two-way after pump 6, all the way by coupling the second displacement liquid container 7-2 after the first tripper 12-1, another way passes through second
The displacement liquid container of connection first 7-1 after tripper 12-2；
The exogenous displacement liquid container 13 of one end connection of exogenous displacement liquid container liquid back pipe road 15, the other end is divided into two
Road, all the way by coupling the second displacement liquid container 7-2 after the first tripper 12-1, another way passes through the second tripper 12-2
The displacement liquid container of connection first 7-1 afterwards；
The first tripper 12-1, the second tripper 12-2 are coordinated signals, when the first tripper 12-1 is opened
When logical, the second tripper 12-2 close automatically, when the first tripper 12-1 is closed, the second tripper 12-2 opens automatically
It is logical.
It is made up of as shown in figure 4, being additionally provided with the front end on drain pipe road 5 ultrafiltration pipeline 16, ultrafiltrate pump 17, ultrafiltration container 18
Ultrafiltration system.
The ultrafiltration system also includes flow-monitoring device, and the flow-monitoring device is arranged on ultrafiltration pipeline 16, right
Flow rate of liquid and flow in ultrafiltration pipeline 16 are monitored.
The first tripper 12-1, the second tripper 12-2 are tubing clamp.
It can also be with two cavitys being isolated from each other on a device to replace liquid container 7.
The first tripper 12-1 can also be the tripper group being made up of single or multiple trippers, each disconnected
Road device returns to drain pipe road 5, liquid back pipe road 8, exogenous displacement liquid container drain pipe road 14, exogenous displacement liquid container respectively
Liquid pipeline 15 carries out coordinated signals；
The second tripper 12-2 can also be the tripper group of single or multiple trippers composition, each open circuit
Device returns liquid to drain pipe road 5, liquid back pipe road 8, exogenous displacement liquid container drain pipe road 14, exogenous displacement liquid container respectively
Pipeline 15 carries out coordinated signals.
It is 100-500ml that first fluid circulation system, which exchanges volume,.
The first tripper 12-1, the second tripper 12-2 are provided with fault alarm.
Flow monitor is additionally provided with the drain pipe road 5 or liquid back pipe road 8.
Displacement liquid container 7 in first fluid circulation system can also be set to more than 2.
Embodiment 4：Be dialysis mode structure as shown in Fig. 5,6,7, when for dialysis mode when, displacement liquid/dialysis fluid container
Commonly referred to as dialysis fluid container；Exogenous displacement liquid/dialysis fluid container is commonly referred to as exogenous dialysis fluid container, displacement liquid with thoroughly
Analysis liquid is identical liquid, and the container for containing the liquid is also identical container, and the call that container respectively forms component is related to " putting
Change ", " dialysis " two word, according to the difference of Therapeutic mode, select " displacement " call different from " dialysis ".
A kind of continous way CRRT machine capability bascules of two tripper, including by entering blood vessel road 1, blood pump 2, hollow
The blood circulation system that fiber dialysis device 3, blood back pipeline 4 form, by drain pipe road 5, liquid pump 6, dialysis fluid container 7, hollow
The first fluid circulation system that fiber dialysis device 3, liquid back pipe road 8 form；
Blood circulation system and the first fluid circulation system use common hollow fiber dialyzer 3, blood circulation system
In blood and the dialyzate in the first fluid circulation system solute carried out by common hollow fiber dialyzer 3 exchanged；
Hollow fiber dialyzer 3 includes blood inlet 9-1, blood outlet 9-2, dialyzate outlet 10, dialyzate entrance 11,
Dialyzate outlet 10, dialyzate entrance 11 are commonly referred to as hollow fiber dialyzer fluid port；
It is described enter blood vessel road 1 one end introduce patient vessel after, by blood pump 2 through the other end couple hollow fiber dialyzer
3 blood inlet 9-1, the blood outlet 9-2 of one end connection hollow fiber dialyzer 3 of the blood back pipeline 4, the other end is by blood
Liquid feeds back patient's body；
Dialysis fluid container 7 in first fluid circulation system has two, is the first dialysis fluid container 7-1, second saturating
Analyse liquid container 7-2.
The dialyzate outlet 10 of one end connection hollow fiber dialyzer 3 on the drain pipe road 5, the other end passes through liquid pump
It is divided into two-way after 6, all the way by coupling the first dialysis fluid container 7-1 after the first tripper 12-1, another way is broken by second
Couple the second dialysis fluid container 7-2 after the device 12-2 of road；
The dialyzate entrance 11 of one end connection hollow fiber dialyzer 3 on the liquid back pipe road 8, the other end is divided into two-way,
All the way by coupling the first dialysis fluid container 7-1 after the first tripper 12-1, after another way is by the second tripper 12-2
Couple the second dialysis fluid container 7-2；
Also include being filled by exogenous dialysis fluid container 13, exogenous dialysis fluid container drain pipe road 14, liquid pump 6, open circuit
Put 12-1,12-2, dialysis fluid container 7, the second liquid circulatory system of exogenous dialysis fluid container liquid back pipe road 15 composition；
Described exogenous one end of dialysis fluid container drain pipe road 14 couples exogenous dialysis fluid container 13, and the other end is through liquid
It is divided into two-way after pump 6, all the way by coupling the second dialysis fluid container 7-2 after the first tripper 12-1, another way passes through second
Couple the first dialysis fluid container 7-1 after tripper 12-2；
Described exogenous one end of dialysis fluid container liquid back pipe road 15 couples exogenous dialysis fluid container 13, and the other end is divided into two
Road, all the way by coupling the second dialysis fluid container 7-2 after the first tripper 12-1, another way passes through the second tripper 12-2
After couple the first dialysis fluid container 7-1；
The first tripper 12-1, the second tripper 12-2 are coordinated signals, when the first tripper 12-1 is opened
When logical, the second tripper 12-2 close automatically, when the first tripper 12-1 is closed, the second tripper 12-2 opens automatically
It is logical.
It is made up of as shown in fig. 6, being additionally provided with the front end on drain pipe road 5 ultrafiltration pipeline 16, ultrafiltrate pump 17, ultrafiltration container 18
Ultrafiltration system.
The ultrafiltration system also includes flow-monitoring device, and the flow-monitoring device is arranged on ultrafiltration pipeline 16, right
Flow rate of liquid and flow in ultrafiltration pipeline 16 are monitored.
The first tripper 12-1, the second tripper 12-2 are tubing clamp.
Dialysis fluid container 7 can also be with two cavitys being isolated from each other on a device.
The first tripper 12-1 can also be the tripper group being made up of single or multiple trippers, each disconnected
Road device returns to drain pipe road 5, liquid back pipe road 8, exogenous dialysis fluid container drain pipe road 14, exogenous dialysis fluid container respectively
Liquid pipeline 15 carries out coordinated signals；
The second tripper 12-2 can also be the tripper group of single or multiple trippers composition, each open circuit
Device returns liquid to drain pipe road 5, liquid back pipe road 8, exogenous dialysis fluid container drain pipe road 14, exogenous dialysis fluid container respectively
Pipeline 15 carries out coordinated signals.
It is 100-500ml that first fluid circulation system, which exchanges volume,.
The first tripper 12-1, the second tripper 12-2 are provided with fault alarm.
Flow monitor is additionally provided with the drain pipe road 5 or liquid back pipe road 8.
Dialysis fluid container 7 in first fluid circulation system can also be set to more than 2.
Claims (10)
1. a kind of continous way CRRT machine capability bascules of two tripper, including by entering blood vessel road, blood pump, hollow fibre
The blood circulation system of dialyzer, blood back pipeline composition, by drain pipe road, liquid pump, displacement liquid/dialysis fluid container, hollow fibre
Tie up dialyzer, the first fluid circulation system of liquid back pipe road composition；
Blood circulation system and the first fluid circulation system use common hollow fiber dialyzer, the blood in blood circulation system
Liquid carries out solute by common hollow fiber dialyzer with displacement liquid/dialyzate in the first fluid circulation system and exchanged；
Hollow fiber dialyzer includes blood inlet, blood outlet, displacement liquid/dialyzate outlet, displacement liquid/dialyzate entrance,
Displacement liquid/dialyzate outlet, displacement liquid/dialyzate entrance are commonly referred to as hollow fiber dialyzer fluid port；
It is described enter blood vessel road one end introduce patient vessel after, pass through blood pump through the other end couple hollow fiber dialyzer blood
Import, the blood outlet of one end connection hollow fiber dialyzer of the blood back pipeline, the other end is by blood recovery patient's body；
It is characterized in that：Displacement liquid/dialysis fluid container in first fluid circulation system has two, be the first displacement liquid/
Dialysis fluid container, the second displacement liquid/dialysis fluid container；
The drain pipe road one end connection hollow fiber dialyzer fluid port, the other end by being divided into two-way after liquid pump,
All the way by coupling the first displacement liquid/dialysis fluid container after the first tripper, another way after the second tripper by coupling
Second displacement liquid/dialysis fluid container；
One end connection hollow fiber dialyzer fluid port on the liquid back pipe road enters blood vessel road, and the other end is divided into two-way, and one
Road is by coupling the first displacement liquid/dialysis fluid container after the first tripper, another way is by coupling after the second tripper
Two displacement liquids/dialysis fluid container；
Also include by exogenous displacement liquid/dialysis fluid container, exogenous displacement liquid/dialysis fluid container drain pipe road, liquid pump, disconnected
The second liquid cyclic system of road device, displacement liquid/dialysis fluid container, exogenous displacement liquid/dialysis fluid container liquid back pipe road composition
System；
The exogenous displacement liquid/dialysis fluid container drain pipe road one end couples exogenous displacement liquid/dialysis fluid container, the other end
It is divided into two-way after liquid pump, all the way by coupling the second displacement liquid/dialysis fluid container after the first tripper, another way passes through
Couple the first displacement liquid/dialysis fluid container after second tripper；
The exogenous displacement liquid/dialysis fluid container liquid back pipe road one end couples exogenous displacement liquid/dialysis fluid container, the other end
It is divided into two-way, all the way by coupling the second displacement liquid/dialysis fluid container after the first tripper, another way is filled by the second open circuit
Postpone connection the first displacement liquid/dialysis fluid container；
First tripper, the second tripper are coordinated signals, when the first tripper is opened, the second tripper
Automatic closure, when the first tripper closes, the second tripper it is automatically open-minded.
2. the continous way CRRT machine capability bascules of two tripper according to claim 1, it is characterised in that：
The front end on drain pipe road is additionally provided with the ultrafiltration system being made up of ultrafiltration pipeline, ultrafiltrate pump, ultrafiltration container.
3. the continous way CRRT machine capability bascules of two tripper according to claim 2, it is characterised in that：Institute
Stating ultrafiltration system also includes flow-monitoring device, and the flow-monitoring device is arranged on ultrafiltration pipeline, in ultrafiltration pipeline
Flow rate of liquid and flow are monitored.
4. the continous way CRRT machine capability bascules of two tripper according to claim 1, it is characterised in that：Institute
State the first tripper, the second tripper is tubing clamp.
5. the continous way CRRT machine capability bascules of two tripper according to claim 1, it is characterised in that：Put
It can also be with two cavitys being isolated from each other on a device to change liquid/dialysis fluid container.
6. the continous way CRRT machine capability bascules of two tripper according to claim 1, it is characterised in that：Institute
It can also be tripper group to state the first tripper, and each tripper is respectively to drain pipe road, liquid back pipe road, exogenous displacement
Liquid/dialysis fluid container drain pipe road, exogenous displacement liquid/dialysis fluid container liquid back pipe road carry out coordinated signals；
Second tripper can also be tripper group, and each tripper is respectively to drain pipe road, liquid back pipe road, external source
Property displacement liquid/dialysis fluid container drain pipe road, exogenous displacement liquid/dialysis fluid container liquid back pipe road carries out coordinated signals.
7. the continous way CRRT machine capability bascules of two tripper according to claim 1, it is characterised in that：The
It is 100-500ml that one fluid circulation system, which exchanges volume,.
8. the continous way CRRT machine capability bascules of two tripper according to claim 1, it is characterised in that：Institute
State the first tripper, the second tripper is provided with fault alarm.
9. the continous way CRRT machine capability bascules of two tripper according to claim 1, it is characterised in that：Institute
State and be additionally provided with flow monitor on drain pipe road or liquid back pipe road.
10. the continous way CRRT machine capability bascules of two tripper according to claim 1, it is characterised in that：
Displacement liquid/dialysis fluid container in first fluid circulation system can also be set to more than 2.
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| CN100444906C (en) * | 2005-03-11 | 2008-12-24 | 暨南大学 | Fluid-balancing liquid-supplying device and its application |
| DE102009058681A1 (en) * | 2009-12-16 | 2011-06-22 | Fresenius Medical Care Deutschland GmbH, 61352 | Balancing device, external medical functional device, treatment device and method |
| DE102010023635A1 (en) * | 2010-06-14 | 2011-12-15 | Fresenius Medical Care Deutschland Gmbh | Device and method for conveying liquids into the treatment unit of a medical treatment device, in particular into the dialyzer of a dialysis machine |
| DE102012009043A1 (en) * | 2012-05-04 | 2013-11-07 | Fresenius Medical Care Deutschland Gmbh | Balancing device, dialysis machine, extracorporeal circuit and method for balancing liquids with a flow cell |
| CN203677608U (en) * | 2013-12-19 | 2014-07-02 | 上海市同济医院 | Device for adopting CRRT machine to perform blood purification united ascites ultra-filtration reinfusion |
| CN203989201U (en) * | 2014-08-15 | 2014-12-10 | 中国人民解放军第三军医大学第二附属医院 | A kind of based on Diapact CRRT machine and for the improved device of Cured by Double Filtration Plasmapheresis plasmapheresis |
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