CN105725114A - Roxburgh rose fruit composite function health care product and preparation method and application thereof - Google Patents

Roxburgh rose fruit composite function health care product and preparation method and application thereof Download PDF

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CN105725114A
CN105725114A CN201610079589.8A CN201610079589A CN105725114A CN 105725114 A CN105725114 A CN 105725114A CN 201610079589 A CN201610079589 A CN 201610079589A CN 105725114 A CN105725114 A CN 105725114A
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parts
rosae normalis
fructus rosae
function health
product
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程克勇
程华
程序
程庆
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/385—Concentrates of non-alcoholic beverages
    • A23L2/39—Dry compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C11/00—Milk substitutes, e.g. coffee whitener compositions
    • A23C11/02—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins
    • A23C11/10—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins containing or not lactose but no other milk components as source of fats, carbohydrates or proteins
    • A23C11/103—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins containing or not lactose but no other milk components as source of fats, carbohydrates or proteins containing only proteins from pulses, oilseeds or nuts, e.g. nut milk
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/156—Flavoured milk preparations ; Addition of fruits, vegetables, sugars, sugar alcohols or sweeteners
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    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/074—Ganoderma
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
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    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K36/8988—Gastrodia
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23C2240/00—Use or particular additives or ingredients
    • A23C2240/15—Use of plant extracts, including purified and isolated derivatives thereof, as ingredient in dairy products
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/30—Extraction of the material
    • A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
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Abstract

The invention provides a roxburgh rose fruit composite function health care product, a preparation method of the roxburgh rose fruit composite function health care product and a product prepared further.The roxburgh rose fruit composite function health care product is mainly prepared from, by weight, 30-40 parts of roxburgh rose fruits, 2-4 parts of wild sweet potatoes, 15-20 parts of broadleaf holly leaves, 3-7 parts of ganoderma, 2-6 parts of radix ophiopogonis, 6-10 parts of polygonatum kingianum rhizomes, 2-5 parts of peper mulberry fruits, 5-10 parts of honey, 2-7 parts of rhizoma gastrodiae, 2-4 parts of fruits of thorny elaeagnus, 0.5-2 parts of benzoin and 3-7 parts of bark of eucommia.The preparation method mainly comprises the steps that the raw materials are smashed, subjected to supercritical CO2 extraction, purified, and dried, and powder is prepared.The roxburgh rose fruit composite function health care product can be further made into a particle product or added into dairy products or drinks or oral liquid and the like to make out corresponding products.The roxburgh rose fruit composite function health care product is rich in nutrition and has a health care function.

Description

A kind of Fructus Rosae Normalis complex function health product and its preparation method and application
Technical field
The present invention relates to herb medicine field, in particular to a kind of Fructus Rosae Normalis complex function Health product and its preparation method and application.
Background technology
Along with the progress of society, improving constantly of living standard, people are to healthy understanding also More and more comprehensively and rationality.Beverage in the market is a feast for the eyes, the most each own respective Feature, but be also respectively arranged with deficiency, thus various beverage can commercially and deposit, and Accepted by people.
Fructus Rosae Normalis: nutritious, contains 12 contained by the vegetable material generally acknowledged both at home and abroad Planting vitamin, wherein Vc, VE, VPP, carotene carotene content enrich, (super rich in SOD Superoxide dismutase), polyphenols, Polysaccharides from Rosa roxburghii, containing 18 kinds of aminoacid, and 18 kinds of trace element such as ferrum, phosphorus, zinc, selenium, calcium, wherein Vc content average out to 2087mg/100ml, Fructus Rosae Normalis has fruit " king Vc ", " fruits nutrition storehouse " laudatory title accordingly, than Containing Fructus actinidiae chinensis about high ten times world-famous for Vc.
It has proven convenient that Fructus Rosae Normalis has the obvious effect preventing human body various organ generation tumor, have good The function of good discharge heavy metal in human body (lead), has antioxidation, functions of removing chloasma (beauty treatment), promotees Enter Digestion, prevent and treat coronary heart disease, antianginal, relieving asthma, antibacterial, antitumor, control Treat skin carcinoma and early cervical carcinoma, prevent the curative effect of the multiple diseases such as hypercholesterolemia, have anti- Old and feeble function.
The traditional Chinese medical science thinks that Fructus Rosae Normalis has clearing away summer-heat, the function of the stomach function regulating that helps digestion, for summer-heat impairment of body fluid, Restlessness and thirst, oliguria with reddish urine, eating accumulation, chamber distention and fullness in the abdomen, eat diarrhoea less.
Applicant of the present invention proposed entitled " a kind of Fructus Rosae Normalis natural juice fresh-keeping in 1993 And add fragrant method ", the application for a patent for invention of Publication No. CN1088412A.But it is this The product that nutritional labeling, function are the most single does not clearly fulfils the health demand of modern.
Summary of the invention
The first object of the present invention is to provide a kind of Fructus Rosae Normalis complex function health product, described Fructus Rosae Normalis complex function health product have nutritious, without advantages such as harmful substances.
In order to realize the above-mentioned purpose of the present invention, spy by the following technical solutions:
A kind of Fructus Rosae Normalis complex function health product, by parts by weight, mainly by following raw material Make: Fructus Rosae Normalis 35 parts, wild country melon 2-4 part, Folium Ilicis 15-20 part, Ganoderma 3-7 part, Radix Ophiopogonis 2-6 part, Rhizoma Polygonati 6-10 part, Fructus Broussonetiae 2-5 part, Mel 5-10 part, Rhizoma Gastrodiae 2-6 Part, sheep milk milk 2-4 part, Benzoinum 0.5-2 part and Cortex Eucommiae 3-7 part.
The second object of the present invention is to provide a kind of described Fructus Rosae Normalis complex function health product Preparation method, the product that the method prepares all has purity and active constituent content advantages of higher.
In order to realize the above-mentioned purpose of the present invention, spy by the following technical solutions:
The preparation method of a kind of Fructus Rosae Normalis complex function health product, comprises the following steps:
Pulverize and immersion step: first by Fructus Rosae Normalis, wild country melon, Folium Ilicis, Ganoderma, Radix Ophiopogonis, Rhizoma Polygonati, Fructus Broussonetiae, Mel, Rhizoma Gastrodiae, sheep milk milk, Benzoinum and the Cortex Eucommiae pulverize broken wall treatment Obtain mixture of powders, then obtain mixture of powders water infiltration infiltrating thing；Wherein, The particle diameter of mixture of powders is 0.04-0.1mm, and mixture of powders with the weight ratio of water is 1:2.5-5；
Extraction step: first with dynamic countercurrent device, infiltration thing is extracted and obtains the first extraction Thing, then puts into the infiltration thing processed extractor together with the first extract and faces with super Boundary CO2Extract and be extracted mixture, after extraction terminates, extraction mixture is subtracted Pressure isolated the second extract；Wherein, extracting pressure is 7.38-30MPa, extraction temperature For 31.1-46.1 DEG C, extraction time is 20-60min；
Purification and concentration step: after removing the water in the second extract, impurity, obtain purified；
Finished product step: purified is carried out spray drying and sterilizing prepares powder, then by powder Health product are made in agent.
The third object of the present invention is to provide three kinds of described Fructus Rosae Normalis complex function health product Deep processed product.
Specifically include:
The application in milk product and beverage of the Fructus Rosae Normalis complex function health product.
The application in Chinese drugs agentia of the Fructus Rosae Normalis complex function health product.
Compared with prior art, the invention have the benefit that
(1) raw material selected by is common Chinese herbal medicine or food materials, does not contains harmful Material, the reasonable and mutual coordinated of each material matching, final complex function health product Comprehensive nutrition.
(2) the complex function health product of the present invention have strengthening vital QI to eliminate pathogenic factors, tonifying five ZANG-organs, peace spirit, Determine soul, to palpitation with fear, invigorating primordial QI, liver and kidney tonifying, Yin-nourishing and body fluid promoting, harmonizing yingfen and weifen QI and blood, work The sweet acid of blood blood stasis dispelling function is pure, the heart Yi Kou that oozes, have Fructus Rosae Normalis, Folium Eriobotryae fragrance flavour gas The special health drink with function of taste.Obvious health-care efficacy, quote requirement by product, nontoxic pair Effect.
(3) the complex function health product of the present invention can make granule, milk product, oral liquid With the deep processed product of the various ways such as beverage, convenient use, also allow for promoting.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but this Skilled person is it will be appreciated that the following example is merely to illustrate the present invention, and should not regard For limiting the scope of the present invention.Unreceipted actual conditions person in embodiment, according to normal condition Or the condition of manufacturer's suggestion is carried out.Agents useful for same or instrument unreceipted production firm person, all For the conventional products that can be obtained by commercially available purchase.
The invention provides a kind of Fructus Rosae Normalis complex function health product, by parts by weight, main To be made up of following raw material: Fructus Rosae Normalis 30-40 part, wild country melon 2-4 part, Folium Ilicis 15-20 Part, Ganoderma 3-7 part, 2-6 part Radix Ophiopogonis, Rhizoma Polygonati 6-10 part, Fructus Broussonetiae 2-5 part, Mel 5-10 part, Rhizoma Gastrodiae 2-7 part, sheep milk milk 2-4 part, Benzoinum 0.5-2 part and Cortex Eucommiae 3-7 part.
The designer of the present invention is by long-term exploration and trial, and experiment repeatedly and exerting Power, constantly reforms and innovates, elite determine Fructus Rosae Normalis, wild country melon, Folium Ilicis, Ganoderma, Radix Ophiopogonis, Rhizoma Polygonati, Fructus Broussonetiae, Mel, Rhizoma Gastrodiae, sheep milk milk, Benzoinum and the Cortex Eucommiae as raw material, if Count out this Fructus Rosae Normalis complex function health product, this Fructus Rosae Normalis complex function health product local flavor is good, Nutritious, there is preferable health-care effect.
Fructus Rosae Normalis: Classification system is Rosa roxbunghii, be rosaceous plant fruit (and Root, stem, leaf, flower), containing SOD, vitamin C, Citrin, multiple human body must The aminoacid of need, enzyme, peptide active component.Have help digestion, expelling summer-heat, the function become thin.
Wild country melon: Classification system is Ficus tikoua Bur, be also called ground Folium Eriobotryae, fruit or Fructus Fici tikouae, is the fruit of moraceae plants Radix Pachyrhizi Erosi, containing Quercetin, polysaccharide, sterol active matter Matter.There is the function of clearing away heat-damp and promoting diuresis, strengthening spleen and middle warmer.
Folium Ilicis: Classification system is Ilex latifolia Thunb, is oleaceae plant Japan female Genuine leaf, fruit, containing Fructus Ligustri Lucidi acid, ursolic acid, oleanolic acid and copper, ferrum, zinc, Manganese, selenium and other trace elements.Have invigorating middle warmer, settling five organs, go out all kinds of diseases and ailments, control body volume, insomnia, The function of aphtha.
Ganoderma: Classification system is Ganoderma Lucidum, is On Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Sporophore, rich in polypeptide, aminoacid, water-solubility protein body and polysaccharide active components, tool Control dizziness, cardiopalmus, insomnia, stagnation of liver-QI costalgia, effect of cough.
Radix Ophiopogonis: Classification system is Ophiopogon Japonicus, it is also called native Radix Ophiopogonis, is The tuber of liliaceous plant Radix Ophiopogonis, containing ophiopagonin A.B.C isoreactivity composition.Have Mend five kinds of strain and seven kinds of impairment, nourishing the lung to arrest cough, the function of the relieving restlessness that clears away heart-fire.
Rhizoma Polygonati: Classification system is Polygonatum sibiricum, is liliaceous plant Rhizoma Polygonati Rhizome, different by shape, practise and claim " big Rhizoma Polygonati ", " polygonatum sibiricum Redoute " " RHIZOMA POLYGONATI ZINGIBERIFORME ", Containing polygonatum polysaccharide, glycosides, lysine isoreactivity material, office mend five kinds of strain and seven kinds of impairment, help muscles and bones, Granulation promoting, resistance to cold and summer-heat, strengthening the spleen stomach, the function of profit cardiopulmonary.
Fructus Broussonetiae: Classification system is Broussonetia papyrifera, is moraceae plants Broussonetia papyrifera Fruit, containing the sub-glycosides of Fructus Aurantii Immaturus, linoleic acid, vitamin B isoreactivity composition.Have and control essence and blood Virtual loss early whitening of beard and hair, the function such as old blurring of vision, the soreness of waist of suffering from a deficiency of the kidney, weak, stubborn dermatitis sufferings.
Rhizoma Gastrodiae: Classification system is Gastrodia elata Blume, is the block of orchid Rhizoma Gastrodiae Stem, containing gastrodine, antifungal protein, vanillyl alcohol, aldehyde, citric acid, succinic acid, Trace element and the active component such as vitamin A and fluorine, manganese, zinc, iodine.Have dispel external it Evil, the expectorant kept away by interior, promoting blood circulation, muscles and bones contracture paralysis, " god's medicine also " it in all blood deficiency diseases Function.
Mel: Apidae insecticide apis cerana (Apiscerana Fabricius) or apis mellifera Linnaeus The honey that (Apismellifera Linnaeus) is made, has heat-clearing and toxic substances removing, invigorating middle warmer pain relieving, enhancing Immunity of organism, cardiac nutrition, promotion gastrointestinal smooth muscle are wriggled, anti-swollen disease, strengthening by means of tonics, Promote tissue regeneration, coagulant blood, blood pressure lowering, antiinflammatory, the function of analgesia.
Sheep milk milk: Classification system is Elaeagnus pungens Thunb, calls Fructus Elaeagni, Milk daughter root, half spring or half, containing the spring, are fruit and the root of Elaeangnaceae plant Fructus elaeagni glabrae. Containing oleanolic acid isoreactivity composition, have and control cough with copious phlegm, insomnia, traumatic injury, rheumatism The function of arthralgia pain.
Benzoinum: Classification system is Styraxbenzond, is the resin of Styracaceae plant, Containing active skull cap components such as total cinnamic acids.There is stimulation respiratory mucosa secrete, eliminate the phlegm, open Key, control the function of qi depression to blood stasis.
The Cortex Eucommiae: Classification system is Eucomunia uimoides oliv, is Eucommiaceae plant Bark.Containing eucommioside, genipin (Genipin) chlorogenic acid, cystine etc. 17 kinds trip Isolated amino acid and 15 kinds of inorganic elementss such as germanium, selenium.Tool nourishing kidney tonifying liver is empty, fill bone, be good for muscle Function.Have that " void of all parts of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, the non-Cortex Eucommiae is not mended；The part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels wet, the non-Cortex Eucommiae is unfavorable； The Cortex Eucommiae sour, non-of foot shin is not gone；Soreness of waist and knee joint, the non-Cortex Eucommiae is not removed；" good reputation.
As preferably, Fructus Rosae Normalis complex function health product according to weight portion mainly by Fructus Rosae Normalis 35 parts, Wild country melon 2-3 part, Folium Ilicis 16-20 part, Ganoderma 4-6 part, 3-5 part Radix Ophiopogonis, Rhizoma Polygonati 6-10 part, Fructus Broussonetiae 2-4 part, Mel 6-8 part, Rhizoma Gastrodiae 3-5 part, sheep milk milk 2-3 part, Benzoinum 0.5-1.5 part and Cortex Eucommiae 4-6 part are made.
As preferably, Fructus Rosae Normalis complex function health product according to weight portion mainly by Fructus Rosae Normalis 35 parts, 2.5 parts of wild country melon, Folium Ilicis 18 parts, Ganoderma 5 parts, Radix Ophiopogonis 4 parts, Rhizoma Polygonati 8 parts, paper mulberry Real son 3 parts, Mel 7 parts, 4 parts of Rhizoma Gastrodiae, sheep milk milk 2.5 parts, Benzoinum 1 part and Du Make for secondary 5 parts.
The preparation method of a kind of Fructus Rosae Normalis complex function health product, comprises the following steps:
Pulverize and immersion step: first by Fructus Rosae Normalis, wild country melon, Folium Ilicis, Ganoderma, Radix Ophiopogonis, Rhizoma Polygonati, Fructus Broussonetiae, Mel, Rhizoma Gastrodiae, sheep milk milk, Benzoinum and the Cortex Eucommiae pulverize broken wall treatment Obtain mixture of powders, then obtain mixture of powders water infiltration infiltrating thing；Wherein, The particle diameter of mixture of powders is 0.04-0.1mm, and mixture of powders with the weight ratio of water is 1:2.5-5；
Extraction step: first with dynamic countercurrent device, infiltration thing is extracted and obtains the first extraction Thing, then puts into the infiltration thing processed extractor together with the first extract and faces with super Boundary CO2Extract and be extracted mixture, after extraction terminates, extraction mixture is subtracted Pressure isolated the second extract；Wherein, extracting pressure is 7.38-30MPa, extraction temperature For 31.1-46.1 DEG C, extraction time is 20-60min；
Purification and concentration step: after the second extract is carried out remove impurity, concentration, obtain purified；
Finished product step: purified is made health product.
Selected raw material belongs to plant, and the minimum component units of plant is cell, fabric exhausted Major part nutritional labeling and active substance are stored within intracellular.The purpose pulverized is in order to the greatest extent Destroy the cell wall of raw material possibly, it is simple to nutritional labeling and the extraction of active substance.Prepare Powder diameter preferable when 0.04-0.1mm.
As preferably, the particle diameter of mixture of powders is 0.04-0.6mm.
As preferably, extracting pressure is 20-30MPa, and extraction temperature is 35-46.1 DEG C, extraction The time of taking is 40-60min.
As preferably, purification and concentration step be: first uses macroporous adsorbent resin to remove second Impurity in extract, the most again by the second extract in the condition that temperature is-20 DEG C～-18 DEG C Under carry out freeze concentration process obtain purified.
Macroporous adsorbent resin is also called macroporous resin, has loose structure to molecular size not Same material has screening effect.The present invention is mainly used for and degerms and macromole The impurity such as protein.As preferably, the aperture of macroporous adsorbent resin is 0.1-0.5 micron.
The purified that above-mentioned steps prepares is liquid, and this purified can make powder further End, granule, beverage and milk product etc..
As preferably, described finished product step is: is spray-dried by described purified and goes out Bacterium makes powder product.
The powder prepared in finished product step can use directly as solid beverage.Due to powder Volume makes moist, and is unfavorable for preserving, so being processed further powder the most again.
As preferably, finished product step is: first adding additive to purified, additive is with pure The mass ratio of compound is 0.04-0.06:1, then carries out being spray-dried and sterilizing, so by purified After purified sent into granulator made particulate matter, the particle diameter of particulate matter is 0.3-0.5mm, Again particulate matter through ionized water eluting and is dried to obtain grain products.
As preferably, the condition of sterilizing is: temperature is 125-135 DEG C, and the time is 8-12s.
As preferably, additive is polylactic-co-glycolic acid, Polyethylene Glycol and hydroxyethyl methyl At least one in cellulose.
Select additive primarily to be easy to be processed into powder larger-size granule, have It is beneficial to preserve, and is conducive to absorbing.The active component of this health product is up to more than ten kinds, Amount of activated material contacts with gastric acid and can be destroyed.After addition additive makes granule, granule Will not all in stomach digested fall, partial particulate can enter intestinal, is inhaled in intestinal Receive.
Above-mentioned purified, powder product and grain products all can be further processed into Beverage, milk product and Chinese drugs agentia etc., Chinese drugs agentia includes injection, tablet, unguentum and soup Agent etc..
Embodiment 1
The preparation method of a kind of Fructus Rosae Normalis complex function health product, comprises the following steps:
Pulverize and immersion step: first by 35 parts of Fructus Rosae Normalis, 2 portions of wild country melons, 15 parts of Folium Ilicis, 3 portions of Ganodermas, 2 parts of Radix Ophiopogonis, 6 parts of Rhizoma Polygonatis, 2 parts of Fructus Broussonetiaes, 5 parts of Mel, 2 parts of Rhizoma Gastrodiaes, 2 portions of sheep milk milk, 0.5 part of Benzoinum and 3 parts of Cortexs Eucommiae are pulverized broken wall treatment and are obtained mixture of powders, Then obtain mixture of powders water infiltration infiltrating thing；Wherein, the particle diameter of mixture of powders For 0.04mm, mixture of powders is 1:2.5 with the weight ratio of water.
Extraction step: first with dynamic countercurrent device, infiltration thing is extracted and obtains the first extraction Thing, then puts into the infiltration thing processed extractor together with the first extract and faces with super Boundary CO2Extract and be extracted mixture, extraction mixture mainly containing protein, aminoacid, Inorganic salt, glycoside, sterol, aromatic series Alkaloid, vitamin, organic acid natural activity Composition, presents orange red or micro-brownish red separator；After extraction terminates, extraction mixture is entered Row decompression separation obtains the second extract；Wherein, extracting pressure is 7.38MPa, extraction temperature Degree is 31.1 DEG C, and extraction time is 60min.
Purification and concentration step: first use that macroporous adsorbent resin removes in the second extract is miscellaneous Matter, carries out freeze concentration process by the second extract the most again under conditions of temperature is for-20 DEG C Obtain purified.
Finished product step: be spray-dried by purified, then at the bar that temperature is 125 DEG C Under part, sterilizing 12s prepares powder.
The powder prepared can be added to the water directly as product, in milk product or beverage In take, mouthfeel is good, have strengthening vital QI to eliminate pathogenic factors, tonifying five ZANG-organs, peace spirit, determine soul, to shy Throb with fear, invigorating primordial QI, liver and kidney tonifying, Yin-nourishing and body fluid promoting, harmonizing yingfen and weifen QI and blood, blood circulation promoting and blood stasis dispelling function Sweet acid is pure, the heart Yi Kou that oozes, have Fructus Rosae Normalis, Folium Eriobotryae fragrance flavour abnormal smells from the patient.
Embodiment 2
The preparation method of a kind of Fructus Rosae Normalis complex function health product, comprises the following steps:
Pulverize and immersion step: first by 35 parts of Fructus Rosae Normalis, 3 portions of wild country melons, 16 parts of Folium Ilicis, 4 portions of Ganodermas, 3 parts of Radix Ophiopogonis, 6 parts of Rhizoma Polygonatis, 2 parts of Fructus Broussonetiaes, 6 parts of Mel, 3 parts of Rhizoma Gastrodiaes, 2.5 portions of sheep milk milk, 1 part of Benzoinum and 4 parts of Cortexs Eucommiae are pulverized broken wall treatment and are obtained mixture of powders； Wherein, the particle diameter of mixture of powders is 0.05mm, and mixture of powders with the weight ratio of water is 1:3。
Extraction step: first with dynamic countercurrent device, infiltration thing is extracted and obtains the first extraction Thing, then puts into the infiltration thing processed extractor together with the first extract and faces with super Boundary CO2Extract and be extracted mixture, extraction mixture mainly containing protein, aminoacid, Inorganic salt, glycoside, sterol, aromatic series Alkaloid, vitamin, organic acid natural activity Composition, presents orange red or micro-brownish red separator；After extraction terminates, extraction mixture is entered Row decompression separation obtains the second extract；Wherein, extracting pressure is 8MPa, extraction temperature Being 32 DEG C, extraction time is 50min.
Purification and concentration step: first use that macroporous adsorbent resin removes in the second extract is miscellaneous Matter, carries out freeze concentration process by the second extract the most again under conditions of temperature is for-20 DEG C Obtain purified.
Finished product step: first add polylactic-co-glycolic acid, polylactic-co-glycolic acid to purified It is 0.04:1 with the mass ratio of purified, then purified is spray-dried, then in temperature Degree be 130 DEG C under conditions of sterilizing 10s, then purified is sent into and granulator is made granule Thing, the particle diameter of particulate matter is 0.3mm (particle surface is smooth, substantially in the spherical shape of rule), Again particulate matter through ionized water eluting and is dried to obtain grain products.
In the present embodiment, the final product prepared is grain products, similar with powder, Ke Yijia Entering and take in water, in milk product or in beverage, mouthfeel is good, has strengthening vital QI to eliminate pathogenic factors, mends five Dirty, peace spirit, determine soul, extremely palpitation with fear, invigorating primordial QI, liver and kidney tonifying, Yin-nourishing and body fluid promoting, mediation The four stages in the course of an epidemic febrile disease, blood circulation promoting and blood stasis dispelling function sweet acid is pure, the heart Yi Kou that oozes, have Fructus Rosae Normalis, Pi Rake fragrance flavour abnormal smells from the patient.
The application of a kind of Fructus Rosae Normalis complex function health product, by the milk after sterilization and granule Product is configured to milk product according to 100:5.Certainly milk can also replace to other animal milks, Or change vegetable milk such as bean milk, Semen arachidis hypogaeae milk etc. into.Grain products ratio in milk product is also Can adjust.
Embodiment 3
The preparation method of a kind of Fructus Rosae Normalis complex function health product, comprises the following steps:
Pulverize and immersion step: first by 35 parts of Fructus Rosae Normalis, 2.5 portions of wild country melons, 18 parts of Folium Ilicis, 5 portions of Ganodermas, 4 parts of Radix Ophiopogonis, 8 parts of Rhizoma Polygonatis, 3 parts of Fructus Broussonetiaes, 7 parts of Mel, 4 parts of Rhizoma Gastrodiaes, 2.5 portions of sheep milk milk, 1 part of Benzoinum and 5 parts of Cortexs Eucommiae are pulverized broken wall treatment and are obtained mixture of powders； Wherein, the particle diameter of mixture of powders is 0.06mm, and mixture of powders with the weight ratio of water is 1:4。
Extraction step: first with dynamic countercurrent device, infiltration thing is extracted and obtains the first extraction Thing, then puts into the infiltration thing processed extractor together with the first extract and faces with super Boundary CO2Extract and be extracted mixture, extraction mixture mainly containing protein, aminoacid, Inorganic salt, glycoside, sterol, aromatic series Alkaloid, vitamin, organic acid natural activity Composition, presents orange red or micro-brownish red separator；After extraction terminates, extraction mixture is entered Row decompression separation obtains the second extract；Wherein, extracting pressure is 15MPa, extraction temperature Being 35 DEG C, extraction time is 45min.
Purification and concentration step: first use that macroporous adsorbent resin removes in the second extract is miscellaneous Matter, carries out freeze concentration process by the second extract the most again under conditions of temperature is for-18 DEG C Obtain purified.
Finished product step: first add hydroxyethylmethyl-cellulose to purified, hydroxyethyl methyl is fine Dimension element is 0.05:1 with the mass ratio of purified, then is spray-dried by purified, then Sterilizing 8s under conditions of temperature is 135 DEG C, then sends into purified in granulator and makes Particulate matter, the particle diameter of particulate matter is that (particle surface is smooth, substantially in the ball of rule for 0.4mm Shape), then particulate matter through ionized water eluting and is dried to obtain grain products.
In the present embodiment, the final product prepared is grain products, similar with powder, Ke Yijia Entering and take in water, in milk product or in beverage, mouthfeel is good, has strengthening vital QI to eliminate pathogenic factors, mends five Dirty, peace spirit, determine soul, extremely palpitation with fear, invigorating primordial QI, liver and kidney tonifying, Yin-nourishing and body fluid promoting, mediation The four stages in the course of an epidemic febrile disease, blood circulation promoting and blood stasis dispelling function sweet acid is pure, the heart Yi Kou that oozes, have Fructus Rosae Normalis, Pi Rake fragrance flavour abnormal smells from the patient.
The application of a kind of Fructus Rosae Normalis complex function health product, by the milk after sterilization and granule Product is configured to milk product according to 100:5.Certainly milk can also replace to other animal milks, Or change vegetable milk such as bean milk, Semen arachidis hypogaeae milk etc. into.Grain products ratio in milk product is also Can adjust.
Embodiment 4
The preparation method of a kind of Fructus Rosae Normalis complex function health product, comprises the following steps:
Pulverize and immersion step: first by 35 parts of Fructus Rosae Normalis, 3 portions of wild country melons, 20 parts of Folium Ilicis, 6 portions of Ganodermas, 5 parts of Radix Ophiopogonis, 10 parts of Rhizoma Polygonatis, 4 parts of Fructus Broussonetiaes, 8 parts of Mel, 5 parts of Rhizoma Gastrodiaes, 3 portions of sheep milk milk, 1.5 parts of Benzoinumes and 6 parts of Cortexs Eucommiae are pulverized broken wall treatment and are obtained mixture of powders； Wherein, the particle diameter of mixture of powders is 0.06mm, and mixture of powders with the weight ratio of water is 1:5。
Extraction step: first with dynamic countercurrent device, infiltration thing is extracted and obtains the first extraction Thing, then puts into the infiltration thing processed extractor together with the first extract and faces with super Boundary CO2Extract and be extracted mixture, extraction mixture mainly containing protein, aminoacid, Inorganic salt, glycoside, sterol, aromatic series Alkaloid, vitamin, organic acid natural activity Composition, presents orange red or micro-brownish red separator；After extraction terminates, extraction mixture is entered Row decompression separation obtains the second extract；Wherein, extracting pressure is 20MPa, extraction temperature Being 40 DEG C, extraction time is 30min；
Purification and concentration step: first use that macroporous adsorbent resin removes in the second extract is miscellaneous Matter, carries out freeze concentration process by the second extract the most again under conditions of temperature is for-18 DEG C Obtain purified.
Finished product step: first add the mass ratio of additive, additive and purified to purified For 0.04-0.06:1, additive is made up of polylactic-co-glycolic acid and hydroxyethylmethyl-cellulose, Polylactic-co-glycolic acid and hydroxyethylmethyl-cellulose respectively account for the half of the quality of additive；Again Purified is spray-dried, then sterilizing 10s under conditions of temperature is 130 DEG C, so After purified sent into granulator made particulate matter, the particle diameter of particulate matter is 0.4mm (granule Smooth surface, substantially in the spherical shape of rule), then particulate matter through ionized water eluting and is done Dry obtain grain products.
In the present embodiment, the final product prepared is grain products, similar with powder, Ke Yijia Entering and take in water, in milk product or in beverage, mouthfeel is good, has strengthening vital QI to eliminate pathogenic factors, mends five Dirty, peace spirit, determine soul, extremely palpitation with fear, invigorating primordial QI, liver and kidney tonifying, Yin-nourishing and body fluid promoting, mediation The four stages in the course of an epidemic febrile disease, blood circulation promoting and blood stasis dispelling function sweet acid is pure, the heart Yi Kou that oozes, have Fructus Rosae Normalis, Pi Rake fragrance flavour abnormal smells from the patient.
The application of a kind of Fructus Rosae Normalis complex function health product, by the milk after sterilization and granule Product is configured to milk product according to 100:5.Certainly milk can also replace to other animal milks, Or change vegetable milk such as bean milk, Semen arachidis hypogaeae milk etc. into.Grain products ratio in milk product is also Can adjust.
Embodiment 5
The preparation method of a kind of Fructus Rosae Normalis complex function health product, comprises the following steps:
Pulverize and immersion step: first by 35 parts of Fructus Rosae Normalis, 4 portions of wild country melons, 20 parts of Folium Ilicis, 7 portions of Ganodermas, 6 parts of Radix Ophiopogonis, 10 parts of Rhizoma Polygonatis, 5 parts of Fructus Broussonetiaes, 10 parts of Mel, 6 parts of Rhizoma Gastrodiaes, 4 portions of sheep milk milk, 0.5 part of Benzoinum and 3 parts of Cortexs Eucommiae are pulverized broken wall treatment and are obtained mixture of powders； Wherein, the particle diameter of mixture of powders is 0.08mm, and mixture of powders with the weight ratio of water is 1:3。
Extraction step: first with dynamic countercurrent device, infiltration thing is extracted and obtains the first extraction Thing, then puts into the infiltration thing processed extractor together with the first extract and faces with super Boundary CO2Extract and be extracted mixture, extraction mixture mainly containing protein, aminoacid, Inorganic salt, glycoside, sterol, aromatic series Alkaloid, vitamin, organic acid natural activity Composition, presents orange red or micro-brownish red separator；After extraction terminates, extraction mixture is entered Row decompression separation obtains the second extract；Wherein, extracting pressure is 25MPa, extraction temperature Being 35 DEG C, extraction time is 30min.
Purification and concentration step: first use that macroporous adsorbent resin removes in the second extract is miscellaneous Matter, carries out freeze concentration process by the second extract the most again under conditions of temperature is for-20 DEG C Obtain purified.
Finished product step: first add polylactic-co-glycolic acid, polylactic-co-glycolic acid to purified It is 0.05:1 with the mass ratio of purified, then purified is spray-dried, then in temperature Degree be 125 DEG C under conditions of sterilizing 10s, then purified is sent into and granulator is made granule Thing, the particle diameter of particulate matter is 0.3mm (particle surface is smooth, substantially in the spherical shape of rule), Again particulate matter through ionized water eluting and is dried to obtain grain products.
In the present embodiment, the final product prepared is grain products, similar with powder, Ke Yijia Entering and take in water, in milk product or in beverage, mouthfeel is good, has strengthening vital QI to eliminate pathogenic factors, mends five Dirty, peace spirit, determine soul, extremely palpitation with fear, invigorating primordial QI, liver and kidney tonifying, Yin-nourishing and body fluid promoting, mediation The four stages in the course of an epidemic febrile disease, blood circulation promoting and blood stasis dispelling function sweet acid is pure, the heart Yi Kou that oozes, have Fructus Rosae Normalis, Pi Rake fragrance flavour abnormal smells from the patient.
The application of a kind of Fructus Rosae Normalis complex function health product, is dissolved in water grain products, then Add adjuvant and be fabricated to tablet.
Embodiment 6
The preparation method of a kind of Fructus Rosae Normalis complex function health product, comprises the following steps:
Pulverize and immersion step: first by 30 parts of Fructus Rosae Normalis, 2 portions of wild country melons, 15 parts of Folium Ilicis, 3 portions of Ganodermas, 2 parts of Radix Ophiopogonis, 6 parts of Rhizoma Polygonatis, 2 parts of Fructus Broussonetiaes, 5 parts of Mel, 3 parts of Rhizoma Gastrodiaes, 2 portions of sheep milk milk, 0.5 part of Benzoinum and 3 parts of Cortexs Eucommiae are pulverized broken wall treatment and are obtained mixture of powders； Wherein, the particle diameter of mixture of powders is 0.04mm, and mixture of powders with the weight ratio of water is 1:2.5。
Extraction step: first with dynamic countercurrent device, infiltration thing is extracted and obtains the first extraction Thing, then puts into the infiltration thing processed extractor together with the first extract and faces with super Boundary CO2Extract and be extracted mixture, extraction mixture mainly containing protein, aminoacid, Inorganic salt, glycoside, sterol, aromatic series Alkaloid, vitamin, organic acid natural activity Composition, presents orange red or micro-brownish red separator；After extraction terminates, extraction mixture is entered Row decompression separation obtains the second extract；Wherein, extracting pressure is 30MPa, extraction temperature Being 46.1 DEG C, extraction time is 20min.
Purification and concentration step: first use that macroporous adsorbent resin removes in the second extract is miscellaneous Matter, carries out freeze concentration process by the second extract the most again under conditions of temperature is for-20 DEG C Obtain purified.
Finished product step: first add polylactic-co-glycolic acid, polylactic-co-glycolic acid to purified It is 0.06:1 with the mass ratio of purified, then purified is spray-dried, then in temperature Degree be 135 DEG C under conditions of sterilizing 10s, then purified is sent into and granulator is made granule Thing, the particle diameter of particulate matter is 0.5mm (particle surface is smooth, substantially in the spherical shape of rule), Again particulate matter through ionized water eluting and is dried to obtain grain products.
In the present embodiment, the final product prepared is grain products, similar with powder, Ke Yijia Entering and take in water, in milk product or in beverage, mouthfeel is good, has strengthening vital QI to eliminate pathogenic factors, mends five Dirty, peace spirit, determine soul, extremely palpitation with fear, invigorating primordial QI, liver and kidney tonifying, Yin-nourishing and body fluid promoting, mediation The four stages in the course of an epidemic febrile disease, blood circulation promoting and blood stasis dispelling function sweet acid is pure, the heart Yi Kou that oozes, have Fructus Rosae Normalis, Pi Rake fragrance flavour abnormal smells from the patient.
The application of a kind of Fructus Rosae Normalis complex function health product, joins grain products with fat, sugar and water Make beverage.The fill specification of this beverage can be 200mL, 250mL and 500mL Deng.The oral liquid of 10-20mL can be become with fill.
Embodiment 7
The preparation method of a kind of Fructus Rosae Normalis complex function health product, comprises the following steps:
Pulverize and immersion step: first by 40 parts of Fructus Rosae Normalis, 2 portions of wild country melons, 15 parts of Folium Ilicis, 3 portions of Ganodermas, 2 parts of Radix Ophiopogonis, 6 parts of Rhizoma Polygonatis, 2 parts of Fructus Broussonetiaes, 5 parts of Mel, 2 parts of Rhizoma Gastrodiaes, 2 portions of sheep milk milk, 0.5 part of Benzoinum and 3 parts of Cortexs Eucommiae are pulverized broken wall treatment and are obtained mixture of powders； Wherein, the particle diameter of mixture of powders is 0.1mm, and mixture of powders is 1:5 with the weight ratio of water.
Extraction step: first with dynamic countercurrent device, infiltration thing is extracted and obtains the first extraction Thing, then puts into the infiltration thing processed extractor together with the first extract and faces with super Boundary CO2Extract and be extracted mixture, extraction mixture mainly containing protein, aminoacid, Inorganic salt, glycoside, sterol, aromatic series Alkaloid, vitamin, organic acid natural activity Composition, presents orange red or micro-brownish red separator；After extraction terminates, extraction mixture is entered Row decompression separation obtains the second extract；Wherein, extracting pressure is 10MPa, extraction temperature Being 35 DEG C, extraction time is 30min.
Purification and concentration step: first use that macroporous adsorbent resin removes in the second extract is miscellaneous Matter, carries out freeze concentration process by the second extract the most again under conditions of temperature is for-18 DEG C Obtain purified.
Finished product step: first add hydroxyethylmethyl-cellulose to purified, hydroxyethyl methyl is fine Dimension element is 0.05:1 with the mass ratio of purified, then is spray-dried by purified, then Sterilizing 10s under conditions of temperature is 130 DEG C, then sends into purified in granulator and makes Particulate matter, the particle diameter of particulate matter is that (particle surface is smooth, substantially in the ball of rule for 0.4mm Shape), then particulate matter through ionized water eluting and is dried to obtain grain products.
In the present embodiment, the final product prepared is grain products, similar with powder, Ke Yijia Entering and take in water, in milk product or in beverage, mouthfeel is good, has strengthening vital QI to eliminate pathogenic factors, mends five Dirty, peace spirit, determine soul, extremely palpitation with fear, invigorating primordial QI, liver and kidney tonifying, Yin-nourishing and body fluid promoting, mediation The four stages in the course of an epidemic febrile disease, blood circulation promoting and blood stasis dispelling function sweet acid is pure, the heart Yi Kou that oozes, have Fructus Rosae Normalis, Pi Rake fragrance flavour abnormal smells from the patient.
Embodiment 8
The preparation method of a kind of Fructus Rosae Normalis complex function health product, comprises the following steps:
Pulverize and immersion step: first by 35 parts of Fructus Rosae Normalis, 2 portions of wild country melons, 15 parts of Folium Ilicis, 3 portions of Ganodermas, 2 parts of Radix Ophiopogonis, 6 parts of Rhizoma Polygonatis, 2 parts of Fructus Broussonetiaes, 5 parts of Mel, 4 parts of Rhizoma Gastrodiaes, 2 portions of sheep milk milk, 0.5 part of Benzoinum and 3 parts of Cortexs Eucommiae are pulverized broken wall treatment and are obtained mixture of powders； Wherein, the particle diameter of mixture of powders is 0.04mm, and mixture of powders with the weight ratio of water is 1:3。
Extraction step: first with dynamic countercurrent device, infiltration thing is extracted and obtains the first extraction Thing, then puts into the infiltration thing processed extractor together with the first extract and faces with super Boundary CO2Extract and be extracted mixture, extraction mixture mainly containing protein, aminoacid, Inorganic salt, glycoside, sterol, aromatic series Alkaloid, vitamin, organic acid natural activity Composition, presents orange red or micro-brownish red separator；After extraction terminates, extraction mixture is entered Row decompression separation obtains the second extract；Wherein, extracting pressure is 8MPa, extraction temperature Being 36 DEG C, extraction time is 40min.
Purification and concentration step: first use that macroporous adsorbent resin removes in the second extract is miscellaneous Matter, carries out freeze concentration process by the second extract the most again under conditions of temperature is for-19 DEG C Obtain purified.
Finished product step: first add hydroxyethylmethyl-cellulose to purified, hydroxyethyl methyl is fine Dimension element is 0.04:1 with the mass ratio of purified, then is spray-dried by purified, then Sterilizing 12s under conditions of temperature is 125 DEG C, then sends into purified in granulator and makes Particulate matter, the particle diameter of particulate matter is that (particle surface is smooth, substantially in the ball of rule for 0.3mm Shape), then particulate matter through ionized water eluting and is dried to obtain grain products.
In the present embodiment, the final product prepared is grain products, similar with powder, Ke Yijia Entering and take in water, in milk product or in beverage, mouthfeel is good, has strengthening vital QI to eliminate pathogenic factors, mends five Dirty, peace spirit, determine soul, extremely palpitation with fear, invigorating primordial QI, liver and kidney tonifying, Yin-nourishing and body fluid promoting, mediation The four stages in the course of an epidemic febrile disease, blood circulation promoting and blood stasis dispelling function sweet acid is pure, the heart Yi Kou that oozes, have Fructus Rosae Normalis, Pi Rake fragrance flavour abnormal smells from the patient.
Chinese herbal medicine food is the summary of medicine practice over more than 200 years of China, possesses distinct Chinese characteristics Food medicine health care, the application had both considered historical factor (succession), did not the most lose modern research and development sky Between (middle food (medicine) west system).The novel foodstuff of system " definition is advanced, transition of classifying " is modern Science industry (food) project, is autonomous innovation, has independent intellectual property right (patent Protection) project.
The present invention is high-new with Life Sci-Tech, biotechnology, information science technology etc. Technological means, organic integration, according to country's GAP, GMP specification, country's food (medicine) Political affairs " food quality standard ", the regulation of " food quality controls to require ", apply constitutional chemistry (Chinese herbal medicine use active skull cap components) chirality high flux screening, functional effect is good, and poison is secondary Acting on little, mechanism of action is new, and reasonable food product design is various releases food system preparation and various administration System dosage forms.
The present invention makes powder with super micron mill (nanotechnology), and powder is through infiltration skill Art adds dynamic countercurrent extraction, then edible health is lived in the carbon dioxide abstraction Chinese herbal medicine of boundary over zero Property composition (protein (SOD, organic acid, aminoacid, saccharide, trace element etc.), so , to extract purification purified is put by macroporous resin (technology of biological membrane) system and device Concentrate in cryotherapy unit, be dried, by concentrated dry thing and new material (adjuvant DEAE cellulose, Polyethylene Glycol etc.) mix after spray-dried, sterilizing prepares granule, Through ionized water eluting, it is dried to obtain smooth mellow and full, granule that size is complete, through after the assay was approved, Packaging storage gets product.
Application gas chromatograph, efficient liquid phase instrument, trace liquid phase instrument, thin layer chromatogram scanner, Ultra-violet and visible spectrophotometer, infrared spectrophotometer, various microfiltration, ultra-filtration and separation device Ware and medium pressure column chromatography equipment, the quality testing to output object each in stock preparation process monitors.
Although illustrate and describing the present invention with specific embodiment, but it will be appreciated that May be made that without departing from the spirit and scope of the present invention many other change and Amendment.It is, therefore, intended that include in the following claims belonging in the scope of the invention All such changes and modifications.

Claims (10)

1. Fructus Rosae Normalis complex function health product, it is characterised in that in parts by weight, main To be made up of following raw material: Fructus Rosae Normalis 30-40 part, wild country melon 2-4 part, Folium Ilicis 15-20 Part, Ganoderma 3-7 part, 2-6 part Radix Ophiopogonis, Rhizoma Polygonati 6-10 part, Fructus Broussonetiae 2-5 part, Mel 5-10 part, Rhizoma Gastrodiae 2-7 part, sheep milk milk 2-4 part, Benzoinum 0.5-2 part and Cortex Eucommiae 3-7 part.
Fructus Rosae Normalis complex function health product the most according to claim 1, it is characterised in that Described Fructus Rosae Normalis complex function health product are main by described Fructus Rosae Normalis 35 parts in parts by weight, described Wild country melon 2-3 part, described Folium Ilicis 16-20 part, described Ganoderma 4-6 part, described Radix Ophiopogonis 3-5 part, described Rhizoma Polygonati 6-10 part, described Fructus Broussonetiae 2-4 part, described Mel 6-8 part, Described Rhizoma Gastrodiae 3-5 part, described sheep milk milk 2-3 part, described Benzoinum 0.5-1.5 part and described Cortex Eucommiae 4-6 part is made.
Fructus Rosae Normalis complex function health product the most according to claim 1, it is characterised in that Described Fructus Rosae Normalis complex function health product are main by described Fructus Rosae Normalis 35 parts in parts by weight, described 2.5 parts of wild country melon, described Folium Ilicis 18 parts, described Ganoderma 5 parts, described Radix Ophiopogonis 4 parts, Described Rhizoma Polygonati 8 parts, described Fructus Broussonetiae 3 parts, described Mel 7 parts, 4 parts of described Rhizoma Gastrodiae, Described sheep milk milk 2.5 parts, described Benzoinum 1 part and the described Cortex Eucommiae 5 parts are made.
4. a preparation method for Fructus Rosae Normalis complex function health product as claimed in claim 1, it is special Levy and be, comprise the following steps:
Pulverize and immersion step: first by described Fructus Rosae Normalis, described wild country melon, described Folium Ilicis, Described Ganoderma, described Radix Ophiopogonis, described Rhizoma Polygonati, described Fructus Broussonetiae, described Mel, described sky Sheep milk milk numb, described, described Benzoinum and described Cortex Eucommiae pulverizing broken wall treatment obtain powder and mix Compound, then obtains described mixture of powders water infiltration infiltrating thing；Described powder mixes Thing is 1:2.5-5 with the weight ratio of water；
Extraction step: first with dynamic countercurrent device, described infiltration thing is extracted and obtains first Extract, then puts into extraction by the described infiltration thing processed together with described first extract Supercritical CO is used in taking device2Extract and be extracted mixture, after extraction terminates, to described Extraction mixture carries out decompression separation and obtains the second extract；Wherein, extracting pressure is 7.38-30MPa, extraction temperature is 31.1-46.1 DEG C, and extraction time is 20-60min；
Purification and concentration step: obtain pure after described second extract is carried out remove impurity, concentration Compound；
Finished product step: described purified is made health product.
The preparation method of Fructus Rosae Normalis complex function health product the most according to claim 4, its Being characterised by, described purification and concentration step be: first uses macroporous adsorbent resin to remove described Impurity in second extract, is-20 DEG C by described second extract in temperature the most again ～carry out under conditions of-18 DEG C freeze concentration process obtain described purified.
6. according to the preparation side of the Fructus Rosae Normalis complex function health product described in claim 4 or 5 Method, it is characterised in that the condition of described sterilizing is: temperature is 125-135 DEG C, the time is 8-12s。
The preparation method of Fructus Rosae Normalis complex function health product the most according to claim 4, its Being characterised by, described finished product step is: carry out described purified being spray-dried and sterilizing system Become powder product.
The preparation method of Fructus Rosae Normalis complex function health product the most according to claim 4, its Being characterised by, described finished product step is: first add additive to described purified, described in add The mass ratio adding agent and described purified is 0.04-0.06:1, then is sprayed by described purified Mist is dried and sterilizing, is then sent in granulator by described purified and makes particulate matter, described The particle diameter of particulate matter is 0.3-0.5mm, then through ionized water eluting and is done by described particulate matter Dry obtain grain products.
9. the Fructus Rosae Normalis complex function health product described in an any one of claim 1-3 are in breast system Application in product and beverage.
10. the Fructus Rosae Normalis complex function health product described in an any one of claim 1-3 in Application in medicine medicament.
CN201610079589.8A 2016-02-04 2016-02-04 Roxburgh rose fruit composite function health care product and preparation method and application thereof Pending CN105725114A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109349623A (en) * 2018-12-26 2019-02-19 福建深林农业科技有限责任公司 A kind of health meal combination containing wild Rosa roxburghii Tratt
CN112913995A (en) * 2021-03-18 2021-06-08 乐山绿水青山科技有限公司 Roxburgh rose liquid for improving immunity and preparation method thereof
CN112913996A (en) * 2021-03-18 2021-06-08 乐山绿水青山科技有限公司 Rosa roxburghii Tratt liquid for improving sleep quality and preparation method thereof
CN115176951A (en) * 2022-07-15 2022-10-14 贵州大学 Coriolus versicolor fermented roxburgh rose and red rice composite beverage and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN101073433A (en) * 2007-06-22 2007-11-21 上海新康制药厂 Blackthorn pear fruit-juice solid product and its production
CN102266043A (en) * 2010-06-04 2011-12-07 钱立奎 Novel production technology of nutrient health Rosa roxburghii solid beverage

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN101073433A (en) * 2007-06-22 2007-11-21 上海新康制药厂 Blackthorn pear fruit-juice solid product and its production
CN102266043A (en) * 2010-06-04 2011-12-07 钱立奎 Novel production technology of nutrient health Rosa roxburghii solid beverage

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109349623A (en) * 2018-12-26 2019-02-19 福建深林农业科技有限责任公司 A kind of health meal combination containing wild Rosa roxburghii Tratt
CN112913995A (en) * 2021-03-18 2021-06-08 乐山绿水青山科技有限公司 Roxburgh rose liquid for improving immunity and preparation method thereof
CN112913996A (en) * 2021-03-18 2021-06-08 乐山绿水青山科技有限公司 Rosa roxburghii Tratt liquid for improving sleep quality and preparation method thereof
CN115176951A (en) * 2022-07-15 2022-10-14 贵州大学 Coriolus versicolor fermented roxburgh rose and red rice composite beverage and preparation method thereof
CN115176951B (en) * 2022-07-15 2023-06-16 贵州大学 Coriolus versicolor fermented roxburgh rose red rice compound beverage and preparation method thereof

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Application publication date: 20160706