CN105709058A - Traditional Chinese medicine preparation for treating gout caused by stagnant heat and internal depression - Google Patents
Traditional Chinese medicine preparation for treating gout caused by stagnant heat and internal depression Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for treating gout caused by stagnant heat and internal depression.The traditional Chinese medicine preparation is prepared from, by weight, 15-20 parts of blackend swallowwort roots, 15-20 parts of the root bark of the peony tree, 10-15 parts of sweet wormwood herb, 10-15 parts of cortex lycii radicis, 10-15 parts of turtle shells, 15-20 parts of arachnoid cyanotis roots, 10-15 parts of safflower carthamus, 10-15 parts of the roots of shrubby elsholtzia, 10-15 parts of the root of Yunnan madder, 5-10 parts of sealwort, 20-30 parts of milkvetch roots, 10-15 parts of radix angelica sinensis, 10-15 parts of radix codonopsis, 5-10 parts of Indian buead and 5-10 parts of rhizoma alismatis.The traditional Chinese medicine preparation has the advantages that the adopted traditional Chinese medical materials meet the specification of Pharmacopoeia of the People's Republic of China, and the medicine is safe and reliable.The traditional Chinese medical materials are cooperated to treat the internal and external causes of gout caused by stagnant heat and internal depression, and the traditional Chinese medicine preparation has the advantages of being exact in treatment effect, becoming effective rapidly, being high in cure rate, having no side effect and the like when used for treating gout caused by stagnant heat and internal depression.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of treat the Chinese medicine preparation of strongly fragrant type gout in stagnant heat.
Background technology
Gout is the crystal dependency arthrosis caused by monosodium urate salt (MSU) deposition, directly related with the hyperuricemia caused by purine metabolic disturbance and (or) underexcretion, refer in particular to acute characteristic arthritis and chronic gout stone disease, mainly including acute attack arthritis, tophus formation, tophaceous chronic arthritis, urate nephropathy and uric acid lithangiuria, severe one may occur in which joint deformity and renal insufficiency.Gout often accompanies the performances such as abdominal obesity, hyperlipemia, hypertension, type 2 diabetes mellitus and cardiovascular diseases.
Gout can be divided into constitutional and the big class of Secondary cases two according to cause of disease difference.Primary gout refers to getting rid of on the basis of other diseases, caused by congenital purine metabolic disturbance and (or) uric acid excretion disorder；Secondary gout refers to that being secondary to uricopoiesis caused by underexcretion, myeloproliferative disease and chemotherapy of tumors caused by kidney disease or some drugs increases.
Traditional Chinese Medicine is thought, primary disease main pathogenesis is exopathogen retardance meridians, QI-blood circulation is not smooth, so that joint, myalgia, numbness, weigh, joint stuffiness and form arthromyodynia, due to the different in kind of being invaded by exogenous pathogen, or have inclined victory, clinical manifestation is also different, the inclined victor of ailment said due to cold or exposure is migratory arthralgia, ailment said due to cold or exposure benefaction and number becomes, therefore arthralgia migration is indefinite；The inclined victor of cold-evil is arthralgia aggravated by cold, and cold main spasm, its property stagnates, therefore arthralgia has location；The inclined victor of damp is damp arthralgia, moist heavy sticky, therefore articular muscle numbness weighs swelling；Heat victor partially is pyretic arthralgia, meridians accumulation of heat, therefore sees that redness and swelling of joints is scorching hot, and pain can not be near.Arthromyodynia is from the beginning of true card, and then vital QI being weakened and pathogen being violent for a long time, deficiency and excess is held under the arm assorted.Easily there are following three kinds of pathological changes in arthromyodynia.One is that with the passing of time arthromyodynia does not heal, and qi-blood-body fluid is run not smooth, blood-vessel obstructive, and body fluid condenses, so that the turbid numbness resistance meridians of blood stasis expectorant, the cards such as arthroncus, periarticular ecchymosis, tuberosity, joint stuffiness occurs.Two is disease for a long time QI and blood consumption wound, presents that QI and blood is double; two loses or the syndrome of deficiency of both the liver and kidney.Three is that arthromyodynia does not heal, and by meridians and internal organs, internal organs numbness occurs.
Summary of the invention
According to above the deficiencies in the prior art, the present invention provides a kind of and treats the Chinese medicine preparation of strongly fragrant type gout in stagnant heat, and it is evident in efficacy, safe and reliable, have no side effect, and has wide potential applicability in clinical practice.
In stagnant heat, strongly fragrant type gout symptom is redness and swelling of joints twinge, and local swelling deforms, joint stuffiness, and skin color purple is fine, and that presses is slightly hard, perilesional or have " block scrofula " to harden, purplish tongue or have ecchymosis, yellow and thin fur, thready and hesitant pulse or heavy string.For the treatment of type gout strongly fragrant in stagnant heat, traditional therapy is mainly with heat clearing away, blood stasis dispelling, dredging collateral for treatment means, but this treatment means is only started with from the exopathogenic factor of gout disease, ignores the effect of gout endogenous cause of ill.The endogenous cause of ill of gout is due to positive QI-insufficiency or overstrain, and wherein, the improper overstrain that refers to of work and rest, consumption hinders healthy energy or exposure to wind when sweating, and exopathogen is taken advantage of a weak point, so that blockage of meridian, it is seized with terror that QI-blood circulation does not freely form numbness.Positive QI-insufficiency refers to that ferritic is weak, or waits insufficiency of vital energy and blood after being ill, and space between skin and muscles is hollow, and failure of defensive QI to protect the body against pathogen exopathogen is taken advantage of a weak point, and with the passing of time arthromyodynia does not heal, blood-vessel obstructive, and the poly-expectorant in Tianjin is solidifying, by meridians and internal organs, causes internal organs numbness.Therefore, treatment is ignored the treatment to gout endogenous cause of ill, cause that the state of an illness is easily repeatedly over the course for the treatment of, it is impossible to thoroughly cure.Therefore, applicant sums up the following therapeutic scheme of proposition in a large amount of clinics:
Of the present invention a kind of treat the Chinese medicine preparation of strongly fragrant type gout in stagnant heat, it is characterized in that according to parts by weight meter, following raw material of Chinese medicine being prepared from: Radix Cynanchi Atrati 15～20 parts, Cortex Moutan 15～20 parts, Herba Artemisiae Annuae 10～15 parts, Cortex Lycii 10～15 parts, Carapax Trionycis 10～15 parts, Radix Cyanotis arachnoideae 15～20 parts, 10～15 parts of Flos Carthami, Radix Elsholtziae Fruticosae 10～15 parts, Radix Rubiae Yunnanensis 10～15 parts, Rhizoma Polygonati 5～10 parts, the Radix Astragali 20～30 parts, Radix Angelicae Sinensis 10～15 parts, Radix Codonopsis 10～15 parts, 5～10 parts of Poria, Rhizoma Alismatis 5～10 parts.
Wherein, it is preferable that scheme is as follows:
Can be according to parts by weight meter, following raw material of Chinese medicine be prepared from: Radix Cynanchi Atrati 15 parts, Cortex Moutan 15 parts, Herba Artemisiae Annuae 10 parts, Cortex Lycii 10 parts, Carapax Trionycis 10 parts, Radix Cyanotis arachnoideae 15 parts, 10 parts of Flos Carthami, Radix Elsholtziae Fruticosae 10 parts, Radix Rubiae Yunnanensis 10 parts, Rhizoma Polygonati 5 parts, the Radix Astragali 20 parts, Radix Angelicae Sinensis 10 parts, Radix Codonopsis 10 parts, 5 parts of Poria, Rhizoma Alismatis 5 parts.
Can also be according to parts by weight meter, following raw material of Chinese medicine be prepared from: Radix Cynanchi Atrati 20 parts, Cortex Moutan 20 parts, Herba Artemisiae Annuae 15 parts, Cortex Lycii 15 parts, Carapax Trionycis 15 parts, Radix Cyanotis arachnoideae 20 parts, 15 parts of Flos Carthami, Radix Elsholtziae Fruticosae 15 parts, Radix Rubiae Yunnanensis 15 parts, Rhizoma Polygonati 10 parts, the Radix Astragali 30 parts, Radix Angelicae Sinensis 15 parts, Radix Codonopsis 15 parts, 10 parts of Poria, Rhizoma Alismatis 10 parts.
Can also be according to parts by weight meter, following raw material of Chinese medicine be prepared from: Radix Cynanchi Atrati 18 parts, Cortex Moutan 18 parts, Herba Artemisiae Annuae 12 parts, Cortex Lycii 12 parts, Carapax Trionycis 12 parts, Radix Cyanotis arachnoideae 18 parts, 12 parts of Flos Carthami, Radix Elsholtziae Fruticosae 12 parts, Radix Rubiae Yunnanensis 12 parts, Rhizoma Polygonati 8 parts, the Radix Astragali 25 parts, Radix Angelicae Sinensis 12 parts, Radix Codonopsis 12 parts, 8 parts of Poria, Rhizoma Alismatis 8 parts.
Of the present invention a kind of treat the preparation method of the Chinese medicine preparation of strongly fragrant type gout in stagnant heat, prepare in accordance with the following methods: weigh raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10～20 minutes, add water and do not have powder 3～5 centimetres, decoct with high heat and use slow fire boiling again instead 20～30 minutes to boiling, take filtrate；Then adding water and do not have powder 3～5 centimetres, decoct with high heat and use slow fire boiling again instead 15～20 minutes to boiling, then removing slag takes filtrate, and twice filtrate merges.
When taking, each 300ml, one day twice.
Pharmacology analysis:
Radix Cynanchi Atrati: bitter, salty, cold.Return stomach, liver, kidney channel.Clearing away heat and cooling blood, inducing diuresis for treating stranguria syndrome, detoxification sore treatment.For pathogenic warmth wound battalion heating, fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, puerperal fever due to deficiency of blood, pyretic stranguria, stranguria with blood, swollen ulcer drug.
Cortex Moutan: bitter, pungent, is slightly cold.GUIXIN, liver, kidney channel.Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, fall and flutter the pain of injury.
Herba Artemisiae Annuae: bitter, acrid, cold.Return liver, gallbladder meridian.Clearing away summer-heat, except steaming, preventing the attack (or recurrence) of malaria.Generate heat for pathogenic summer-heat, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat.
Cortex Lycii: sweet, cold.Return lung, liver, kidney channel.Removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, interior-heat is quenched one's thirst.
Carapax Trionycis: become, be slightly cold.Return liver, kidney channel.Nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving, bring down a fever except steaming.For fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea, abdominal mass, chronic malaria malaria with splenomegaly.
Radix Cyanotis arachnoideae: pungent micro-hardship, temperature.Promoting the flow of QI in the collateral by warming the meridian, removing damp and stopping pain.Treating rheumatic arthritis, numb limbs and tense tendons.
Flos Carthami: pungent, temperature.GUIXIN, Liver Channel.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Radix Elsholtziae Fruticosae: pained, temperature.Promoting the flow of QI in the collateral by warming the meridian, expelling wind and removing dampness.Treating rheumatic arthralgia.
Radix Rubiae Yunnanensis: bitter, sweet, temperature.Regulating menstruation and activating blood, promoting tissue regeneration by removing blood stasis.For menoxenia, dysmenorrhea, blood deficiency amenorrhea, lumbago due to renal deficiency.
Rhizoma Polygonati: sweet is flat.Return spleen, lung, kidney channel.Boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.
The Radix Astragali: sweet, temperature.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and bursts for a long time and does not hold back, and blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst；Chronic nephritis proteinuria, diabetes.
Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.Replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizziness cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Radix Codonopsis: sweet is flat.Return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
Poria: sweet, light is flat.GUIXIN, lung, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Rhizoma Alismatis: sweet, cold.Return kidney, bladder warp.Diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria；Hyperlipidemia.
In medicament composing prescription of the present invention, for exopathogenic factor, Radix Cynanchi Atrati, Cortex Moutan, Herba Artemisiae Annuae, Cortex Lycii, Carapax Trionycis clearing away heat and cooling blood, blood stasis dispelling, Radix Cyanotis arachnoideae, Flos Carthami, Radix Elsholtziae Fruticosae, Radix Rubiae Yunnanensis promoting the flow of QI in the collateral by warming the meridian, benefiting QI for activating blood circulation；For endogenous cause of ill, Rhizoma Polygonati, the Radix Astragali, Radix Angelicae Sinensis, Radix Codonopsis invigorating QI to consolidate the body surface resistance, tonifying blood and regulating menstruation；Add Poria and Rhizoma Alismatis, it is possible to promote urate excretion, play the effect of auxiliary treatment.
It is an advantage of the current invention that the Chinese medicine used meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.The features such as all medicine phases and endogenous cause of ill and exopathogenic factor for type gout strongly fragrant in stagnant heat are treated, and in treatment stagnant heat, strongly fragrant type gout has determined curative effect, instant effect, cure rate is high, have no side effect.
Outcome measure:
1, inclusion criteria
Choose strongly fragrant type patient with gout 100 example in the stagnant heat made a definite diagnosis, wherein, male 62 example, women 38 example, 68 years old mean age.
2, Therapeutic Method
Take Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 300ml, 15 days courses for the treatment of.
3, evaluation of clinical curative effect standard
Cure: (1) clinical symptom disappearance.(2) in blood and urine, uric acid content is normal, normal renal function.(3) more than 2 years are followed up a case by regular visits to continuously without recurrence.
Take a turn for the better: (1) in the situation of taking medicine, remission.(2) in blood and urine, uric acid content is close to normal, and renal function takes a turn for the better.
Invalid: all diseases are without improvement.
4, result
Curing 44 examples, take a turn for the better 52 examples, invalid 4 examples, and total effective rate is 96%.
It is exemplified below a model case:
(1) Lee, female, 62 years old, people from Qingdao, peasant, extremities joint and knee joint redness twinge, and local swelling deformation, joint stuffiness, skin color and luster was blue, and body of the tongue has ecchymosis, yellow and thin fur, thready pulse.Adopting western medicine at the beginning, effect is undesirable.Then to our hospital, be diagnosed as in stagnant heat strongly fragrant type gout, adopt Drug therapy of the present invention, after three courses for the treatment of, clinical symptom disappearance, blood and in urine uric acid content normal, normal renal function, inform that it adheres to keeping on a diet, strengthening taking exercise.Follow up a case by regular visits to 2 years without recurrence.
Detailed description of the invention
The present invention will be further described by the following examples.
Embodiment 1:
A kind of treat the Chinese medicine preparation of strongly fragrant type gout in stagnant heat, according to parts by weight meter, following raw material of Chinese medicine it is prepared from: Radix Cynanchi Atrati 15 parts, Cortex Moutan 15 parts, Herba Artemisiae Annuae 10 parts, Cortex Lycii 10 parts, Carapax Trionycis 10 parts, Radix Cyanotis arachnoideae 15 parts, 10 parts of Flos Carthami, Radix Elsholtziae Fruticosae 10 parts, Radix Rubiae Yunnanensis 10 parts, Rhizoma Polygonati 5 parts, the Radix Astragali 20 parts, Radix Angelicae Sinensis 10 parts, Radix Codonopsis 10 parts, 5 parts of Poria, Rhizoma Alismatis 5 parts.
Embodiment 2:
A kind of treat the Chinese medicine preparation of strongly fragrant type gout in stagnant heat, according to parts by weight meter, following raw material of Chinese medicine it is prepared from: Radix Cynanchi Atrati 20 parts, Cortex Moutan 20 parts, Herba Artemisiae Annuae 15 parts, Cortex Lycii 15 parts, Carapax Trionycis 15 parts, Radix Cyanotis arachnoideae 20 parts, 15 parts of Flos Carthami, Radix Elsholtziae Fruticosae 15 parts, Radix Rubiae Yunnanensis 15 parts, Rhizoma Polygonati 10 parts, the Radix Astragali 30 parts, Radix Angelicae Sinensis 15 parts, Radix Codonopsis 15 parts, 10 parts of Poria, Rhizoma Alismatis 10 parts.
Embodiment 3:
A kind of treat the Chinese medicine preparation of strongly fragrant type gout in stagnant heat, according to parts by weight meter, following raw material of Chinese medicine it is prepared from: Radix Cynanchi Atrati 18 parts, Cortex Moutan 18 parts, Herba Artemisiae Annuae 12 parts, Cortex Lycii 12 parts, Carapax Trionycis 12 parts, Radix Cyanotis arachnoideae 18 parts, 12 parts of Flos Carthami, Radix Elsholtziae Fruticosae 12 parts, Radix Rubiae Yunnanensis 12 parts, Rhizoma Polygonati 8 parts, the Radix Astragali 25 parts, Radix Angelicae Sinensis 12 parts, Radix Codonopsis 12 parts, 8 parts of Poria, Rhizoma Alismatis 8 parts.
Embodiment 4:
Embodiment 1～3 is prepared in accordance with the following methods: weighs raw material of Chinese medicine according to formula and joins in container, adds water and covers powder immersion 20 minutes, adds water and do not have powder 5 centimetres, decocts with high heat and uses slow fire boiling again instead 30 minutes to boiling, takes filtrate；Then adding water and do not have powder 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 minutes to boiling, then removing slag takes filtrate, and twice filtrate merges.
When taking, each 300ml, one day twice.
Claims (4)
1. treat the Chinese medicine preparation of strongly fragrant type gout in stagnant heat for one kind, it is characterized in that according to parts by weight meter, following raw material of Chinese medicine being prepared from: Radix Cynanchi Atrati 15～20 parts, Cortex Moutan 15～20 parts, Herba Artemisiae Annuae 10～15 parts, Cortex Lycii 10～15 parts, Carapax Trionycis 10～15 parts, Radix Cyanotis arachnoideae 15～20 parts, 10～15 parts of Flos Carthami, Radix Elsholtziae Fruticosae 10～15 parts, Radix Rubiae Yunnanensis 10～15 parts, Rhizoma Polygonati 5～10 parts, the Radix Astragali 20～30 parts, Radix Angelicae Sinensis 10～15 parts, Radix Codonopsis 10～15 parts, 5～10 parts of Poria, Rhizoma Alismatis 5～10 parts.
2. according to claim 1 a kind of treat the Chinese medicine preparation of strongly fragrant type gout in stagnant heat, it is characterized in that according to parts by weight meter, following raw material of Chinese medicine being prepared from: Radix Cynanchi Atrati 15 parts, Cortex Moutan 15 parts, Herba Artemisiae Annuae 10 parts, Cortex Lycii 10 parts, Carapax Trionycis 10 parts, Radix Cyanotis arachnoideae 15 parts, 10 parts of Flos Carthami, Radix Elsholtziae Fruticosae 10 parts, Radix Rubiae Yunnanensis 10 parts, Rhizoma Polygonati 5 parts, the Radix Astragali 20 parts, Radix Angelicae Sinensis 10 parts, Radix Codonopsis 10 parts, 5 parts of Poria, Rhizoma Alismatis 5 parts.
3. according to claim 1 a kind of treat the Chinese medicine preparation of strongly fragrant type gout in stagnant heat, it is characterized in that according to parts by weight meter, following raw material of Chinese medicine being prepared from: Radix Cynanchi Atrati 20 parts, Cortex Moutan 20 parts, Herba Artemisiae Annuae 15 parts, Cortex Lycii 15 parts, Carapax Trionycis 15 parts, Radix Cyanotis arachnoideae 20 parts, 15 parts of Flos Carthami, Radix Elsholtziae Fruticosae 15 parts, Radix Rubiae Yunnanensis 15 parts, Rhizoma Polygonati 10 parts, the Radix Astragali 30 parts, Radix Angelicae Sinensis 15 parts, Radix Codonopsis 15 parts, 10 parts of Poria, Rhizoma Alismatis 10 parts.
4. according to claim 1 a kind of treat the Chinese medicine preparation of strongly fragrant type gout in stagnant heat, it is characterized in that according to parts by weight meter, following raw material of Chinese medicine being prepared from: Radix Cynanchi Atrati 18 parts, Cortex Moutan 18 parts, Herba Artemisiae Annuae 12 parts, Cortex Lycii 12 parts, Carapax Trionycis 12 parts, Radix Cyanotis arachnoideae 18 parts, 12 parts of Flos Carthami, Radix Elsholtziae Fruticosae 12 parts, Radix Rubiae Yunnanensis 12 parts, Rhizoma Polygonati 8 parts, the Radix Astragali 25 parts, Radix Angelicae Sinensis 12 parts, Radix Codonopsis 12 parts, 8 parts of Poria, Rhizoma Alismatis 8 parts.
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101347605A (en) * | 2008-08-15 | 2009-01-21 | 北京和润创新医药科技发展有限公司 | Chinese medicinal composition for treating gout and preparation method and application thereof |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101347605A (en) * | 2008-08-15 | 2009-01-21 | 北京和润创新医药科技发展有限公司 | Chinese medicinal composition for treating gout and preparation method and application thereof |
Non-Patent Citations (2)
| Title |
|---|
| 张光武: "《常见骨关节疾病防治》", 29 February 2012, 金盾出版社 * |
| 徐蕾: "《病风中医特色疗法》", 30 June 2012, 人民军医出版社 * |
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Application publication date: 20160629 |