CN105687027A - Alcohol-free amino acid type rinse-free foam washing solution - Google Patents
Alcohol-free amino acid type rinse-free foam washing solution Download PDFInfo
- Publication number
- CN105687027A CN105687027A CN201610051418.4A CN201610051418A CN105687027A CN 105687027 A CN105687027 A CN 105687027A CN 201610051418 A CN201610051418 A CN 201610051418A CN 105687027 A CN105687027 A CN 105687027A
- Authority
- CN
- China
- Prior art keywords
- content
- ethyl acetate
- foam
- cocos nucifera
- methyl taurine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/046—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
Abstract
The invention provides an alcohol-free amino acid type foaming agent, which is prepared from N-sodium methyl cocoyl taurate, ethyl acetate and water. The invention also provides a gynecologic washing solution, which contains the alcohol-free amino acid type foaming agent and antibacterial and anti-virus pharmaceutical formula components. The antibacterial and anti-virus pharmaceutical formula components can contain phthiobuzonum, chlorhexidine acetate and homoisoflavone in rhizoma polygonati odorati.
Description
Technical field
The present invention relates to women domestic health-care product, be specifically related to a kind of without alcohol amino acid pattern flushing free foam, and with gynaecologic washing lotion that this prepares。
Background technology
Gynaecopathia threatens China's female body healthy, and in rejuvenation trend。China has more than 400,000,000 women and to relate to Amino-Cerv according to statistics。Gynaecopathia prevalence is high, and relapse rate is high。And crowd spreads to low age, intellectual with a senior professional title colony day by day。Cervical cancer is one of modal gynecologic malignant tumor, and human papillomavirus (HPV) infection is the direct cause of disease of cervical cancer, has had proven to more than 40 kind of HPV relevant with cervical cancer and precancerous lesion, and the prevention of this field or the medicine market demand are huge。
At present, the anti-bacterial lotion on market is various in style, and therapeutic domain and effect are each different。Wherein, the protection of gynaecopathia is not convenient is key reason。It is usually used in the gynopathic general spirituosity of decontamination articles for use and abnormal flavour is big, stimulate skin；Need to use in advance, rinse afterwards, actually used very inconvenient。There are sense of discomfort and damage epidermis on the market after more existing disposable washing liquids, often have color and abnormal smells from the patient residual afterwards。How to find a kind of safe, comfortable, disposable, quick-drying, absorb fast, colourless, non-stimulated washing liquid and prevent and auxiliary treatment gynaecopathia is significant。
Summary of the invention
It was found by the inventors of the present invention that adopting N-cocos nucifera oil acyl methyl taurine sodium is host, and ethyl acetate and minimal amount of compatible, under special ratios, it is possible to form the foam that a kind of rate of drying is exceedingly fast。This foam of amino acid pattern without alcohol dramatically speeds up than the dewatering speed of common ethanol based amino acid pattern foam。Compared with conventional decontamination articles for use, this foam has the outstanding advantages such as safe, comfortable, convenient。Compared with existing disposable washing liquid, this foam is entirely free of ethanol, dry rapid。This foam carries antibacterial, the anti-virus formula such as ftibamzone, chlorhexidine acetate, Rhizoma Polygonati Odorati extract, and obtained washing liquid abnormal smells from the patient delicate fragrance is pure, healthy and safe, easy to use, protection skin, greatly facilitates the self-protection of high-risk environment。
The raw material of gynaecologic washing lotion provided by the invention mainly has: N-cocos nucifera oil acyl methyl taurine sodium, ethyl acetate, ftibamzone, chlorhexidine acetate, Rhizoma Polygonati Odorati homoisoflavone, water。
Described gynaecologic washing lotion is prepared as follows:
First weigh certain water in proportion; add foam component (N-cocos nucifera oil acyl methyl taurine sodium, ethyl acetate); stirring makes it dissolve; it is subsequently adding antibacterial, anti-virus pharmaceutical formulation component (ftibamzone, chlorhexidine acetate, Rhizoma Polygonati Odorati homoisoflavone); stirring makes it be uniformly dissolved; finally regulate the pH value of product to 4.0～5.0 by pH adjusting agent (such as HCl, NaOH), to obtain final product。
More specifically, the present invention provides the following:
1., without an alcohol amino acid pattern foam, it comprises N-cocos nucifera oil acyl methyl taurine sodium, ethyl acetate and water。
2., according to the foam described in 1, wherein, in described foam, by the weighing scale of described foam, the content of N-cocos nucifera oil acyl methyl taurine sodium is 50-70%, and the content of ethyl acetate is 20-40%。
3. a gynaecologic washing lotion, described gynaecologic washing lotion comprises foam component and antibacterial, anti-virus pharmaceutical formulation component, and wherein said foam component comprises N-cocos nucifera oil acyl methyl taurine sodium, ethyl acetate and water。
4., according to the gynaecologic washing lotion described in 3, wherein said antibacterial, anti-virus pharmaceutical formulation component comprises ftibamzone, chlorhexidine acetate and Rhizoma Polygonati Odorati homoisoflavone。
5., according to the gynaecologic washing lotion described in 4, it is prepared by the method comprised the following steps:
(1) ftibamzone, chlorhexidine acetate, Rhizoma Polygonati Odorati homoisoflavone, N-cocos nucifera oil acyl methyl taurine sodium, ethyl acetate and deionized water are weighed respectively standby；
(2) ftibamzone, chlorhexidine acetate and Rhizoma Polygonati Odorati homoisoflavone are stirred, be then slowly added into deionized water and stir；
(3) in N-cocos nucifera oil acyl methyl taurine sodium, it is slowly added to ethyl acetate, is subsequently adding a small amount of deionized water and stirs；
(4) step (2) is mixed with step (3) gained and stirs；With
(5) pH value is regulated to 4.0～5.0。
6. according to the gynaecologic washing lotion described in 4; wherein; in described washing liquid; weighing scale by described washing liquid; the content of N-cocos nucifera oil acyl methyl taurine sodium is 50%～70%, and the content of ethyl acetate is 20%～40%, and the content of ftibamzone is 0.1%～0.2%; the content of chlorhexidine acetate is 0.01%～0.02%, and the content of Rhizoma Polygonati Odorati homoisoflavone is 0.5%～1.0%。
7. according to the gynaecologic washing lotion described in 3, it also comprises adjuvant, and described adjuvant is selected from polydimethylsiloxane, essence and alpha-alkene sulfonate (AOS)。
8. according to the gynaecologic washing lotion described in 7; wherein; in described washing liquid; weighing scale by described washing liquid; the content of N-cocos nucifera oil acyl methyl taurine sodium is 50%～70%; the content of ethyl acetate is 20%～40%; the content of ftibamzone is 0.1%～0.2%; the content of chlorhexidine acetate is 0.01%～0.02%; the content of Rhizoma Polygonati Odorati homoisoflavone is 0.5%～1.0%; the content of polydimethylsiloxane is 1.0～5.0%, and the content of essence is 0.1～2.0%, and the content of alpha-alkene sulfonate (AOS) is 0.1%～0.2%。
Detailed description of the invention
Beneficial effects of the present invention is expanded on further below by way of pharmacodynamics test and contrast test。
Embodiment 1
(1) weigh ftibamzone 0.2g, chlorhexidine acetate 0.01g, N-cocos nucifera oil acyl methyl taurine sodium 50g, ethyl acetate 40g, polydimethylsiloxane 1.0g, alpha-alkene sulfonate (AOS) 0.2g, essence 0.1g, 0.2MHCl solution is appropriate, deionized water is standby in right amount。
(2) ftibamzone, chlorhexidine acetate are stirred, be then slowly added into deionized water, stir。
(3) by N-cocos nucifera oil acyl methyl taurine sodium, polydimethylsiloxane, alpha-alkene sulfonate, essence mixing, it is then slowly added into ethyl acetate, is subsequently adding deionized water, stir。
(4) step (2) mixed with step (3) gained and stirs, adding deionized water and stirring uniform so that cumulative volume reaches～100 milliliters。
(5) instill mixed liquor with 0.2MHCl solution, regulate pH value to 4.0。
Embodiment 2
(1) ftibamzone 0.1g, chlorhexidine acetate 0.01g, Rhizoma Polygonati Odorati homoisoflavone (extract from Dandong produce polygonati rhizoma) 0.5g, N-cocos nucifera oil acyl methyl taurine sodium 60g, ethyl acetate 35g, deionized water are weighed standby in right amount。
(2) ftibamzone, chlorhexidine acetate and Rhizoma Polygonati Odorati homoisoflavone are stirred, be then slowly added into deionized water, stir。
(3) in N-cocos nucifera oil acyl methyl taurine sodium, it is slowly added to ethyl acetate, is subsequently adding a small amount of deionized water, stirs。
(4) step (2) is mixed with step (3) gained and stirs。
(5) pH value is regulated to 4.0 with 0.2MHCl solution。
Embodiment 3
(1) ftibamzone 0.15g, chlorhexidine acetate 0.015g, Rhizoma Polygonati Odorati homoisoflavone 0.5g, N-cocos nucifera oil acyl methyl taurine sodium 60g, ethyl acetate 35g, deionized water are weighed standby in right amount。
(2) ftibamzone, chlorhexidine acetate and Rhizoma Polygonati Odorati homoisoflavone are stirred, be then slowly added into deionized water, stir。
(3) in N-cocos nucifera oil acyl methyl taurine sodium, it is slowly added to ethyl acetate, is subsequently adding a small amount of deionized water, stirs。
(4) step (2) is mixed with step (3) gained and stirs。
(5) pH value is regulated to 4.5。
Embodiment 4
(1) ftibamzone 0.2g, chlorhexidine acetate 0.02g, Rhizoma Polygonati Odorati homoisoflavone 0.5g, N-cocos nucifera oil acyl methyl taurine sodium 80g, ethyl acetate 15g, deionized water are weighed standby in right amount。
(2) ftibamzone, chlorhexidine acetate and Rhizoma Polygonati Odorati homoisoflavone are stirred, be then slowly added into deionized water, stir。
(3) in N-cocos nucifera oil acyl methyl taurine sodium, it is slowly added to ethyl acetate, is subsequently adding a small amount of deionized water, stirs。
(4) step (2) is mixed with step (3) gained and stirs。
(5) pH value is regulated to 5.0。
Embodiment 5
The washing liquid of the present invention of Example 1 preparation compares foam-drying speed with domestic tradition washing liquid, and result is table 1 below such as；
Table 1
Experimental result illustrates, the foam washing liquid foam-drying speed of the present invention is than domestic fast 2-3 times of washing liquid foam-drying speed of tradition。
Beneficial effects of the present invention is expanded on further below by way of pharmacodynamics test and contrast test
Test example 1, without alcohol amino acid pattern flushing free foam washing liquid antibacterial activity in vitro test
Inoculating staphylococcus aureus (numbering CICC10001), escherichia coli (numbering CMCC44102), Candida albicans (numbering ATCC10231) in different culture medium respectively, above bacterial strain provides by the Organism Depositary that its numbering is corresponding。At 37 DEG C, cultivate after slowly dripping dilute with water after 24h in culture medium 5% the flushing free foam washing liquid of amino acid pattern without alcohol (embodiment 1 preparation) each 5ml, positive controls drips 5ml normal saline。Observing antibacterial situation through 2 minutes, 4 minutes, 6 minutes, 8 minutes, result is in Table 2。
Table 2 is without the outer antibacterial activity test of alcohol amino acid pattern flushing free foam wash liq
Result shown in table 2 shows: the flushing free foam washing liquid of amino acid pattern without alcohol of the present invention has the antibacterial activity of wide spectrum, within 2 minutes, almost can kill vagina encountered pathogenic bacteria。
Test example 2, vaginal mucomembranous irritant test
The female large ear rabbit of New Zealand (Beijing Experimental Amimal Research Centre's offer) 4, body weight 2.2～2.6kg are provided, are divided into experimental group 2 and negative control group 2。Temperature: 18 DEG C～22 DEG C, relative humidity 54～66%。Animal is faced upward fixing, expose perineum and vaginal orifice, gently insert vagina after being moistened by conduit normal saline and be about 2.5cm～4cm。Inject the flushing free foam gynaecologic washing lotion of amino acid pattern without alcohol of 2.5ml embodiment 2 preparation with syringe, extract conduit out, complete contamination；Negative control group normal saline does same process。After contamination 24h, adopting aeroembolism method to put to death animal, the complete vagina of taking-up of cutting open the belly, longitudinally slit, whether perusal has the phenomenon such as hyperemia, edema。Test result indicate that: perusal, each group experimental animal vaginal mucosa has no hyperemia, edema, erosion。Under this condition, the stimulation index of vaginal mucosa is 0 by the washing liquid of the present invention, is classified as nonirritant by vaginal mucosa stimulus intensity grade scale。
Stimulation index scoring according to the form below gained to vaginal mucosa
Table 3 vaginal mucosa irritant reaction standards of grading
Note: irritant reaction integration=A+B+C+D
Table 4 vaginal mucosa stimulus intensity classification
| Vaginal mucosa stimulation index | Vaginal mucosa irritant reaction intensity |
| <1 | Nothing |
| 1～< 5 | Extremely light |
| 5～< 9 | Slightly |
| 9～< 12 | Moderate |
| ≥12 | Severe |
Claims (8)
1., without an alcohol amino acid pattern foam, it comprises N-cocos nucifera oil acyl methyl taurine sodium, ethyl acetate and water。
2. foam according to claim 1, wherein, in described foam, by the weighing scale of described foam, the content of N-cocos nucifera oil acyl methyl taurine sodium is 50-70%, and the content of ethyl acetate is 20-40%。
3. a gynaecologic washing lotion, described gynaecologic washing lotion comprises foam component and antibacterial, anti-virus pharmaceutical formulation component, and wherein said foam component comprises N-cocos nucifera oil acyl methyl taurine sodium, ethyl acetate and water。
4. gynaecologic washing lotion according to claim 3, wherein said antibacterial, anti-virus pharmaceutical formulation component comprises ftibamzone, chlorhexidine acetate and Rhizoma Polygonati Odorati homoisoflavone。
5. gynaecologic washing lotion according to claim 4, it is prepared by the method comprised the following steps:
(1) ftibamzone, chlorhexidine acetate, Rhizoma Polygonati Odorati homoisoflavone, N-cocos nucifera oil acyl methyl taurine sodium, ethyl acetate and deionized water are weighed respectively standby；
(2) ftibamzone, chlorhexidine acetate and Rhizoma Polygonati Odorati homoisoflavone are stirred, be then slowly added into deionized water and stir；
(3) in N-cocos nucifera oil acyl methyl taurine sodium, it is slowly added to ethyl acetate, is subsequently adding a small amount of deionized water and stirs；
(4) step (2) is mixed with step (3) gained and stirs；With
(5) pH value is regulated to 4.0～5.0。
6. gynaecologic washing lotion according to claim 4; wherein; in described washing liquid; weighing scale by described washing liquid; the content of N-cocos nucifera oil acyl methyl taurine sodium is 50%～70%, and the content of ethyl acetate is 20%～40%, and the content of ftibamzone is 0.1%～0.2%; the content of chlorhexidine acetate is 0.01%～0.02%, and the content of Rhizoma Polygonati Odorati homoisoflavone is 0.5%～1.0%。
7. gynaecologic washing lotion according to claim 3, it also comprises adjuvant, and described adjuvant is selected from polydimethylsiloxane, essence and alpha-alkene sulfonate (AOS)。
8. gynaecologic washing lotion according to claim 7; wherein; in described washing liquid; weighing scale by described washing liquid; the content of N-cocos nucifera oil acyl methyl taurine sodium is 50%～70%; the content of ethyl acetate is 20%～40%; the content of ftibamzone is 0.1%～0.2%; the content of chlorhexidine acetate is 0.01%～0.02%; the content of Rhizoma Polygonati Odorati homoisoflavone is 0.5%～1.0%; the content of polydimethylsiloxane is 1.0～5.0%, and the content of essence is 0.1～2.0%, and the content of alpha-alkene sulfonate (AOS) is 0.1%～0.2%。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610051418.4A CN105687027A (en) | 2016-01-26 | 2016-01-26 | Alcohol-free amino acid type rinse-free foam washing solution |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610051418.4A CN105687027A (en) | 2016-01-26 | 2016-01-26 | Alcohol-free amino acid type rinse-free foam washing solution |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105687027A true CN105687027A (en) | 2016-06-22 |
Family
ID=56228749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610051418.4A Pending CN105687027A (en) | 2016-01-26 | 2016-01-26 | Alcohol-free amino acid type rinse-free foam washing solution |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105687027A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111135160A (en) * | 2020-01-16 | 2020-05-12 | 上海美浮特生物科技有限公司 | Foam wash-free antibacterial liquid for personal protection and preparation method thereof |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5662890A (en) * | 1992-11-23 | 1997-09-02 | Estee Lauder, Inc. | Self-tanning cosmetic compositions and methods of using the same |
| CN1398956A (en) * | 2002-08-26 | 2003-02-26 | 宋光泉 | Vegetable and fruit detoxicating agent and its prepn |
| CN1742752A (en) * | 2005-10-08 | 2006-03-08 | 晏四平 | Atomizing agent containing medicinal plant oil |
| CN1777411A (en) * | 2003-02-24 | 2006-05-24 | 药品生产公司 | Transmucosal drug delivery system |
| CN1827158A (en) * | 2005-10-18 | 2006-09-06 | 郑起平 | Compound forming agent with zedoary turmeric oil and method for preparing the same |
| CN101032470A (en) * | 2007-04-21 | 2007-09-12 | 郑起平 | Povidone-iodine bubble agent and preparing method |
| CN101242810A (en) * | 2005-06-22 | 2008-08-13 | 伊兰制药国际有限公司 | Nanoparticulate megestrol formulations |
| US20080206155A1 (en) * | 2006-11-14 | 2008-08-28 | Foamix Ltd. | Stable non-alcoholic foamable pharmaceutical emulsion compositions with an unctuous emollient and their uses |
| CN101267804A (en) * | 2003-12-16 | 2008-09-17 | 弗米克斯有限公司 | Oleaginous pharmaceutical and cosmetic foam |
| CN102614124A (en) * | 2012-04-12 | 2012-08-01 | 石家庄诺利达医疗器械有限公司 | Vaginal sterilizing foaming agent and preparation method thereof |
| CN102641314A (en) * | 2011-02-22 | 2012-08-22 | 广州大光制药有限公司 | Medicine composition for preventing and/or treating gynecological diseases |
-
2016
- 2016-01-26 CN CN201610051418.4A patent/CN105687027A/en active Pending
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5662890A (en) * | 1992-11-23 | 1997-09-02 | Estee Lauder, Inc. | Self-tanning cosmetic compositions and methods of using the same |
| CN1398956A (en) * | 2002-08-26 | 2003-02-26 | 宋光泉 | Vegetable and fruit detoxicating agent and its prepn |
| CN1777411A (en) * | 2003-02-24 | 2006-05-24 | 药品生产公司 | Transmucosal drug delivery system |
| CN101267804A (en) * | 2003-12-16 | 2008-09-17 | 弗米克斯有限公司 | Oleaginous pharmaceutical and cosmetic foam |
| CN101242810A (en) * | 2005-06-22 | 2008-08-13 | 伊兰制药国际有限公司 | Nanoparticulate megestrol formulations |
| CN1742752A (en) * | 2005-10-08 | 2006-03-08 | 晏四平 | Atomizing agent containing medicinal plant oil |
| CN1827158A (en) * | 2005-10-18 | 2006-09-06 | 郑起平 | Compound forming agent with zedoary turmeric oil and method for preparing the same |
| US20080206155A1 (en) * | 2006-11-14 | 2008-08-28 | Foamix Ltd. | Stable non-alcoholic foamable pharmaceutical emulsion compositions with an unctuous emollient and their uses |
| CN101032470A (en) * | 2007-04-21 | 2007-09-12 | 郑起平 | Povidone-iodine bubble agent and preparing method |
| CN102641314A (en) * | 2011-02-22 | 2012-08-22 | 广州大光制药有限公司 | Medicine composition for preventing and/or treating gynecological diseases |
| CN102614124A (en) * | 2012-04-12 | 2012-08-01 | 石家庄诺利达医疗器械有限公司 | Vaginal sterilizing foaming agent and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 刘华钢: "《中药化妆品学》", 30 November 2006 * |
| 罗明生等: "《药剂辅料大全》", 31 January 2006, 四川科学技术出版社 * |
| 马榴强: "《精细化工工艺学》", 29 February 2008, 化学工业出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111135160A (en) * | 2020-01-16 | 2020-05-12 | 上海美浮特生物科技有限公司 | Foam wash-free antibacterial liquid for personal protection and preparation method thereof |
| CN111135160B (en) * | 2020-01-16 | 2021-05-28 | 上海美浮特生物科技有限公司 | Foam wash-free antibacterial liquid for personal protection and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102416023B (en) | Periplaneta Americana L. gel externally applied medicinal composition and preparation method and use thereof in preparation of externally applied medicines for treating scalding | |
| CN102836367B (en) | Bacteria-resisting, inflammation-diminishing and itching-relieving traditional Chinese medicine composition and preparation method and application thereof | |
| CN106420381A (en) | Novel applications of artemisinin ingredients or composition of artemisinin ingredients in skin care | |
| CN105582383A (en) | Composition containing alkannin and lemon grass essential oil | |
| CN109010124B (en) | Marine refined gynecological antibacterial gel and preparation method thereof | |
| CN104288222B (en) | A kind of Nano medication for treating cow endometritis and preparation method thereof | |
| CN109316537A (en) | A kind of vaginal care antibacterial gel and preparation method and application | |
| CN105963243B (en) | A kind of borneol cinnamomum camphora essential oil sustained release emulsifiable paste and preparation method thereof for treating acne vulgaris | |
| CN102397444A (en) | Nano-grade gynaecological lotion and preparation method thereof | |
| CN105687027A (en) | Alcohol-free amino acid type rinse-free foam washing solution | |
| CN101780205B (en) | Traditional Chinese medicine compound transdermal patch for treating mastitis of dairy cattle and preparation method thereof | |
| CN103213226A (en) | Preparation method of antisepsis and anti-inflammation lubrication-type condom containing natural cinnamyl aldehyde | |
| CN103432049B (en) | Composition with deodorization function | |
| CN106267329A (en) | A kind of plants essential oil gel dressing and its preparation method and application | |
| CN104474148A (en) | Traditional Chinese medicine composition used for treating dermatomycosis and preparation method thereof | |
| CN108324648A (en) | A kind of composition of anti-acne | |
| CN103006681A (en) | Compound emulsifiable paste for treating acne and preparation method thereof | |
| CN107412455A (en) | A kind of natural externally applied pharmaceutical composition for treating fash and preparation method thereof | |
| Song et al. | Lactobacillus plantarum fermented Laminaria japonica alleviates UVB-induced epidermal photoinflammation via the Keap-1/Nrf2 pathway | |
| CN102151310A (en) | Externally applied preparation for diminishing inflammation and swelling, preparation method and detection method thereof | |
| CN108066278A (en) | A kind of gynaecology's gel containing chitosan oligosaccharide and preparation method thereof | |
| CN105056048B (en) | A kind of Amino-Cerv compositions and preparation method thereof | |
| CN112999283A (en) | Gynecological lotion and preparation method thereof | |
| CN109260426A (en) | A kind of disease eliminating powder junction pain-stopping external use Chinese medicine and its preparation method and application | |
| CN104436164A (en) | Foot powder containing biologic peptide composition, as well as preparation thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160622 |