CN105663869A - 一种治疗急性肾炎的中药组合物 - Google Patents
一种治疗急性肾炎的中药组合物 Download PDFInfo
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Abstract
本发明公开了一种治疗急性肾炎的中药组合物,其中药原料及重量份配比为:何首乌10-30份,蛇床子10-20份,牡丹皮5-15份,玉米须10-20份,仙茅10-20份,紫花地丁10-20份,桑白皮10-20份,赤小豆5-15份,夏枯草10-20份,杜仲10-20份,五加皮10-20份,石韦5-15份,仙鹤草10-20份,百合10-20份,牛蒡子5-15份,半枝莲10-20份,肉桂10-20份,葛根5-15份,山茱萸10-20份,甘草5-15份。本发明中药组合物具有补肾助阳、清热利尿、祛风散湿、解毒消肿的功效,其治疗急性肾炎疗效显著,作用可靠。
Description
技术领域
本发明涉及一种传统草药的未确定结构的医用配制品,尤其是一种治疗急性肾炎的中药组合物。
背景技术
急性肾炎又称急性肾小球肾炎,是以急性肾炎综合征为主要临床表现的一组原发性肾小球肾炎。其特点为急性起病,血尿、蛋白尿、水肿和高血压,可伴一过性氮质血症,具有自愈倾向。常见于链球菌感染后,而其他细菌、病毒及寄生虫感染亦可引起。多见于儿童,好发年龄为5—14岁,较少累及中老年人。目前,临床上治疗急性肾炎采用抗生素、激素和利尿、降压类药物治疗,虽见效快,但长期服用副作用大,且容易复发。
中医认为,急性肾炎其主因与肾阴不足有关,再加之外感风邪或皮肤疮毒引起肺卫气化功能失调,以致发生本病。
根据中医理论,针对急性肾炎的发病机理,以祛邪解毒、补肾利尿为治则,进行辩证配伍组方,以达到标本兼治的目的。
发明内容
为了克服现有技术中西药治疗急性肾炎存在副作用大、且容易复发的不足,本发明提供一种配制方便、药源广、成本低、疗效显著、作用可靠、无副作用的治疗急性肾炎的中药组合物。
本发明解决其技术问题所采用的技术方案是:一种治疗急性肾炎的中药组合物,其特征在于:其中药原料及重量份配比为:何首乌10-30份,蛇床子10-20份,牡丹皮5-15份,玉米须10-20份,仙茅10-20份,紫花地丁10-20份,桑白皮10-20份,赤小豆5-15份,夏枯草10-20份,杜仲10-20份,五加皮10-20份,石韦5-15份,仙鹤草10-20份,百合10-20份,牛蒡子5-15份,半枝莲10-20份,肉桂10-20份,葛根5-15份,山茱萸10-20份,甘草5-15份。
本发明的优选技术方案是:一种治疗急性肾炎的中药组合物,其特征在于:其中药原料及重量份配比为:何首乌20份,蛇床子15份,牡丹皮10份,玉米须15份,仙茅15份,紫花地丁15份,桑白皮15份,赤小豆10份,夏枯草15份,杜仲15份,五加皮15份,石韦10份,仙鹤草15份,百合15份,牛蒡子10份,半枝莲15份,肉桂15份,葛根10份,山茱萸15份,甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下,精选药物组方。本发明中药组合物中:何首乌具有养血滋阴、润肠通便、截疟、祛风、解毒的功效;蛇床子具有温肾壮阳、燥湿、祛风、杀虫的功效;牡丹皮具有清热凉血、活血散瘀的功效;玉米须具有利尿、泄热、平肝、利胆的功效;仙茅具有补肾助阳、益精血、强筋骨和行血消肿的功效;紫花地丁具有清热解毒的功效;桑白皮具有泻肺平喘、利水消肿的功效;赤小豆具有利水消肿、解毒排脓的功效;夏枯草具有清肝明目、清热利尿、散结消肿的功效;杜仲具有补肝肾、强筋骨、补中益精气的功效;五加皮具有祛风湿、补肝肾、强筋骨的功效;石韦具有利水通淋、清肺泄热的功效;仙鹤草具有收敛止血、健胃、截疟、解毒疗疮的功效;百合具有养阴润肺、清心安神、滋补精血的功效;牛蒡子具有疏散风热、宣肺透疹、利咽散结、解毒消肿之功效;半枝莲具有清热解毒、散瘀止血、消肿定痛的功效;肉桂具有补火助阳、散寒止痛、活血通经的功效;葛根具有发表解肌、升阳透疹、解热生津的功效;山茱萸具有补益肝肾、涩精固脱的功效;甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明组合物中的药物组分经辩证配伍,在作用上相辅相成,具有协同作用,共奏补肾助阳、清热利尿、祛风散湿、解毒消肿之功效,对急性肾炎达到标本兼治的目的。
本发明组合物的组分均采用天然的中药原料,其配制简便、药源广、成本低。其遵循中医的处方用药原则,各种组分药物采用水煎服用。经临床应用验证,其疗效显著,作用可靠,药性平和,未出现毒副作用,总有效率91.4%,治愈率达68.6%。
具体实施方式
下面结合实施例对本发明做进一步说明。
实施例1
一种治疗急性肾炎的中药组合物,其中药原料及重量配比为:何首乌20g,蛇床子15g,牡丹皮10g,玉米须15g,仙茅15g,紫花地丁15g,桑白皮15g,赤小豆10g,夏枯草15g,杜仲15g,五加皮15g,石韦10g,仙鹤草15g,百合15g,牛蒡子10g,半枝莲15g,肉桂15g,葛根10g,山茱萸15g,甘草10g。
实施例2
一种治疗急性肾炎的中药组合物,其中药原料及重量配比为:何首乌10g,蛇床子20g,牡丹皮5g,玉米须20g,仙茅10g,紫花地丁20g,桑白皮10g,赤小豆15g,夏枯草10g,杜仲20g,五加皮10g,石韦15g,仙鹤草10g,百合20g,牛蒡子5g,半枝莲20g,肉桂10g,葛根15g,山茱萸10g,甘草15g。
实施例3
一种治疗急性肾炎的中药组合物,其中药原料及重量配比为:何首乌30g,蛇床子10g,牡丹皮15g,玉米须10g,仙茅20g,紫花地丁10g,桑白皮20g,赤小豆5g,夏枯草20g,杜仲10g,五加皮20g,石韦5g,仙鹤草20g,百合10g,牛蒡子15g,半枝莲10g,肉桂20g,葛根5g,山茱萸20g,甘草5g。
实施例4
一种治疗急性肾炎的中药组合物,其中药原料及重量配比为:何首乌15g,蛇床子18g,牡丹皮8g,玉米须18g,仙茅12g,紫花地丁18g,桑白皮12g,赤小豆13g,夏枯草12g,杜仲12g,五加皮18g,石韦8g,仙鹤草18g,百合12g,牛蒡子8g,半枝莲12g,肉桂18g,葛根8g,山茱萸18g,甘草8g。
实施例5
一种治疗急性肾炎的中药组合物,其中药原料及重量配比为:何首乌25g,蛇床子12g,牡丹皮13g,玉米须12g,仙茅18g,紫花地丁12g,桑白皮18g,赤小豆8g,夏枯草18g,杜仲12g,五加皮18g,石韦8g,仙鹤草18g,百合12g,牛蒡子13g,半枝莲12g,肉桂18g,葛根8g,山茱萸18g,甘草8g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下:将组方的中药原料放入容器中,加冷水漫过药面,浸泡15~20分钟,再加水没过药面约8厘米,进行第一次煎煮,未沸前采用武火煎煮,沸后用文火煎煮20~30分钟;第二次煎煮,加水没过药面约6厘米,水沸后煎煮15~20分钟。两次煎煮去渣取汁,合并。
本发明以实施例1所给出的一种治疗急性肾炎的中药组合物,做临床疗效总结如下:
一、一般性资料:本发明中药组合物应用于临床观察病例70例,其中男39例,女31例,年龄3~20岁。
二、诊断标准:
根据链球菌感染后1~3周、肾炎综合征表现、一过性血清C3下降,可临床诊断本病。若肾小球滤过率进行性下降或病情于2个月尚未见全面好转者应及时肾活检确诊。
三、用法用量:临床应用时,一天一剂,水煎两遍取汁约400ml,分早、晚两次温热服用,四天为一疗程。
四、疗效标准:
1、治愈:临床症状消失,检查正常;
2、好转:临床症状和体征明显减轻;
3、未愈:症状和体征无明显变化。
五、治疗效果:该临床观察病例中,服药4-12个疗程,治愈48例,好转16例,未愈6例。治疗期间未发生毒副作用。
六、典型病例:
病例1:梁某,男,6岁。就诊时述:发烧后出现急性化脓性扁桃体发炎,后来出现全身水肿,血压升高,出现血尿,医院检查出血清C3下降,诊断为:急性肾炎。服用本发明的中药组合物制备的药剂4个疗程后,水肿有所退散,扁桃体炎症几近消失,血尿消失,但尿液偏黄;继续服用3个疗程,各症状消失,实验室检查指标正常,治愈。
病例2:葛某,女,17岁,就诊自述:背部出现疖肿,而后出现浑身水肿、尿血、头晕(高血压)等症状,实验室检查为:急性肾炎。服用本发明的中药组合物制备的药剂3个疗程后,血压恢复正常,水肿退散1/2;续服2个疗程后,血尿完全消失,实验室指标恢复正常;巩固服用2个疗程后,治愈。
Claims (2)
1.一种治疗急性肾炎的中药组合物,其特征在于:其中药原料及重量份配比为:何首乌10-30份,蛇床子10-20份,牡丹皮5-15份,玉米须10-20份,仙茅10-20份,紫花地丁10-20份,桑白皮10-20份,赤小豆5-15份,夏枯草10-20份,杜仲10-20份,五加皮10-20份,石韦5-15份,仙鹤草10-20份,百合10-20份,牛蒡子5-15份,半枝莲10-20份,肉桂10-20份,葛根5-15份,山茱萸10-20份,甘草5-15份。
2.根据权利要求1所述的一种治疗急性肾炎的中药组合物,其特征在于:其中药原料及重量份配比为:何首乌20份,蛇床子15份,牡丹皮10份,玉米须15份,仙茅15份,紫花地丁15份,桑白皮15份,赤小豆10份,夏枯草15份,杜仲15份,五加皮15份,石韦10份,仙鹤草15份,百合15份,牛蒡子10份,半枝莲15份,肉桂15份,葛根10份,山茱萸15份,甘草10份。
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