CN105661040A - Feed additive and feed - Google Patents
Feed additive and feed Download PDFInfo
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- CN105661040A CN105661040A CN201610112049.5A CN201610112049A CN105661040A CN 105661040 A CN105661040 A CN 105661040A CN 201610112049 A CN201610112049 A CN 201610112049A CN 105661040 A CN105661040 A CN 105661040A
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- dihydroxyacetophenone
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
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Abstract
The invention provides a feed additive. The feed additive is prepared from 2,4-dihydroxyacetophenone. According to the feed additive provided by the invention, the 2,4-dihydroxyacetophenone is adopted as the feed additive, the 2,4-dihydroxyacetophenone used in feed has the effects of promoting the growth and increasing the feed conversion ratio, and the effects are not less than those of olaquindox, and the worse the feeding conditions are, the lower the nutritional level is, and the more obvious effects are obtained; the 2,4-dihydroxyacetophenone also has the effect of enabling skin and bristles of a pig to be red and bright, and the effect is superior to that of an organic arsenic preparation; the 2,4-dihydroxyacetophenone is a good substitute of the olaquindox and the organic arsenic preparation, and is a good feed additive which has no toxic and side effects and can promote the growth of animals. The invention provides the feed. The feed comprises the feed additive in the technical scheme. According to feed provided by the invention, the 2,4-dihydroxyacetophenone is used in the feed for farmed animals and is used as the feed additive, so that the daily weight increment and the feed efficiency of the farmed animals can be increased; meanwhile, the effect of enabling the skin and bristles of the pig to be red and bright is obtained, and the reproduction performance of boars and sows can be increased.
Description
Technical field
The present invention relates to animal-breeding technical field, relate in particular to a kind of feed addictive and feed.
Background technology
2,4-dihydroxyacetophenone, claims again 3, 4-Dihydroxyacetophenone, is the main component of Ranunculaceae Ilex pubescens var. glabra Chang leaf. 2,4-dihydroxy benzenesEthyl ketone be pharmaceutically used for the treatment of coronary heart diseases and angina pectoris, atherosclerotic, chronic obstructive pulmonary disease, diabetes, hypertension,The diseases such as development of fetus is bad, blood supply insufficiency growth retardation, injury of mitochondria, pregnant high disease, vascular endothelial cell damage have goodGood effect, without obvious toxic-side effects.
Owing to there being strong carcinogenicity, LIJUNJING ((ethoxymethyl) quinoline), carbadox, these several growth growth-promoting agents of nitrophenols sodium byForbid both at home and abroad for feed. New product quinocetone and still unratified quinoline match are many is all that quinoxaline class (olaquindox class) is producedProduct generally add olaquindox to promote growth of suckling pigs and to improve food conversion ratio in piglet feed in prior art. But quinolineEthanol has the obvious cumulative toxicity of moderate, and humans and animals is all had to three-induced effect, has been forbidden feedingly by European Union, the U.S., and China alsoForbade using olaquindox in poultry, aquaculture in 2005, similar with olaquindox, quinocetone and quinoline match are many also to be existed equallyProblem. In feed, add organic arsenic preparation (arsanilic acid, Roxarsone) and can cause the effect of pigskin hair glow, but haveMachine arsenic preparation is owing to having carcinogenic teratogenesis mutagenesis and fearful environmental pollution to be forbidden by feed, cultivation, veterinary drug.
Olaquindox and organic arsenic preparation etc. have obvious toxic and side effect as feed addictive, and prior art is badly in need of a kind ofThe feed additive for promoting growth having no side effect. At present, yet there are no 2,4-dihydroxyacetophenone being correlated with as feed addictiveReport.
Summary of the invention
In view of this, the object of the present invention is to provide a kind of feed addictive and feed, feed provided by the invention addsAdding agent can growth promotion and have no side effect.
The invention provides a kind of feed addictive, comprise 2,4-dihydroxyacetophenone.
Preferably, described feed addictive also comprises diluent.
Preferably, described diluent comprises that soy meal, corn flour, wheat flour, fish meal, meat meal tankage, sorghum flour, corn form sedimentPowder, wheat bran, rice bran, paddy meal, assorted dregs of rice powder, stone flour, ferrous fumarate, ferrous sulfate, calcium monohydrogen phosphate, calcium formate, manganese sulfate, oxygenChange one or more in zinc, zeolite powder, medical stone powder, sepiolite powder, lysine, threonine and methionine.
Preferably, the mass ratio of described 2,4-dihydroxyacetophenone and diluent is 100:(0.001～100000).
Preferably, the mass ratio of described 2,4-dihydroxyacetophenone and diluent is 100:(0.1～1000).
The present invention adopts 2,4-dihydroxyacetophenone as feed addictive, and it has and is not less than the short of olaquindox in feedGrowth and the effect of improving food conversion ratio, raising condition is poorer, and trophic level is lower, and effect is more obvious; And it also hasBe superior to the effect that organic female preparation causes the glow of pigskin hair; 2,4-dihydroxyacetophenone be olaquindox, organo-arsenic, carbadox,The good substitute of the products such as nitrophenols sodium, quinocetone, quinoline match are many, (ethoxymethyl) quinoline is a kind of good having no side effectGrowth promotion animal feed additive.
The invention provides a kind of feed, comprise the feed addictive described in technique scheme.
Preferably, the mass content of described 2,4-dihydroxyacetophenone in feed is 0.0001%～20%.
Preferably, the form of described feed comprises mixed fodder, mixed feed, concentrated feed, mine trace element premixClose feed, vitamin premixed feed, mine trace element vitamin compound premix, powered milk substitute class feed, customization premixedOne or more in feed, customized feed, customization pharmaceutical feed and customized feed additive.
Preferably, described feed is cultivated animals feed, described cultivated animals comprise pig, chicken, fish, duck, goose, cat, dog,Ermine, sheep, ox, shrimp, scallop, snake, soft-shelled turtle, tortoise, rabbit, deer or fox.
Preferably, described feed is the feed of the different growth phases of cultivated animals.
The present invention uses 2,4-dihydroxyacetophenone as feed addictive in cultivated animals feed, can improve cultivation and moveThe daily gain of thing and feed efficiency also have the effect that makes the glow of pigskin hair simultaneously.
Experimental result shows, adopts feed addictive provided by the invention 30 days, and pigskin hair glow degree improves from 2～3%To 5～6%, daily gain improves 3～12%, and feed conversion rate improves 3～12%; Good in raising condition, the condition of comprehensive nutritionUnder, improve ratio generally 3～5%; But not comprehensive at feed nutrition, the poor or feeding animals of raising condition is in disease or shouldSwash when state, feed addictive provided by the invention can make daily gain and feed conversion rate is minimum reaches 10～15%, the highest canReach 30～40%. Be applied in sow material, can improve the year litter size and the born weight of piglet of sow, reduce stillborn foetus, weak tire;Be applied in boar daily ration, can significantly improve boar sperm motility rate.
Detailed description of the invention
To the technical scheme in the embodiment of the present invention be clearly and completely described below, obviously, described enforcementExample is only the present invention's part embodiment, instead of whole embodiment. Based on the embodiment in the present invention, this area is commonTechnical staff's all other examples through improving or retouching, all belong to the scope of protection of the invention.
The invention provides a kind of feed addictive, comprise 2,4-dihydroxyacetophenone. In the present invention, described feed addsAdd agent and preferably also comprise diluent. In the present invention, described diluent is preferably soy meal, corn flour, wheat flour, fish meal, meatBone meal, sorghum flour, starch, wheat bran, rice bran, paddy meal, assorted dregs of rice powder, stone flour, ferrous fumarate, ferrous sulfate, calcium monohydrogen phosphate, firstOne in acid calcium, manganese sulfate, zinc oxide, zeolite powder, medical stone powder, sepiolite powder, lysine, threonine and methionine or severalKind; More preferably soy meal, corn flour, wheat flour, fish meal, meat meal tankage, cornstarch, wheat bran, rice bran, paddy meal, assorted dregs of rice powder,One in ferrous fumarate, ferrous sulfate, calcium monohydrogen phosphate, calcium formate, manganese sulfate, lysine, threonine and methionine or severalKind; Most preferably be one in soy meal, corn flour, wheat flour, fish meal, wheat bran, assorted dregs of rice powder, lysine, threonine and methionineKind or several. In the present invention, described feed addictive can be cornstarch, ferrous fumarate or FE-5.
In the present invention, the mass ratio of described 2,4-dihydroxyacetophenone and diluent be preferably 100:(0.001～100000), 100:(0.1～1000 more preferably); More preferably 100:(1～100), most preferably be 100:(30～80). ?In the present invention, the mass ratio of described 2,4-dihydroxyacetophenone and diluent can be (180～500): (500～1200), and alsoCan be (300～400): (800～1000), can also be (330～370): (850～950), can be also 300:1200,180:820 or 500:500.
In the present invention, the mass content of described 2,4-dihydroxyacetophenone in feed addictive can be 0.001%～99.9%, can be also 15%～80%, can be also 18%～60%, can also be 20%～50%.
In the present invention, described feed addictive can be 2,4-dihydroxyacetophenone and cornstarch, described 2,4-bis-The mass content of hydroxy acetophenone in feed addictive is 20%; Also can be 2,4-dihydroxyacetophenone and fumaric acid AsiaIron, the mass content of described 2,4-dihydroxyacetophenone in feed addictive is 18%; Can also be 2,4-dihydroxy benzenes secondKetone and FE-5, the mass content of described 2,4-dihydroxyacetophenone in feed addictive is 50%.
The invention provides a kind of feed, comprise the feed addictive described in technique scheme. In the present invention, described inThe form of feed can be mixed fodder, mixed feed, concentrated feed, mine trace element premixed feed, vitamin premixClose feed, mine trace element vitamin compound premixing feed, powered milk substitute class feed, customization premixed feed, customized feed, fixedPharmacy feed, the multi-form feed of customization additive feed. In the present invention, described 2,4-dihydroxyacetophenone is at feedIn mass content be preferably 0.001%～20%, more preferably 0.01%～15%, more preferably 0.0015%～1.0%,Most preferably be 0.0020%～0.0050%. In the present invention, the mass content of described feed addictive in mixed feed is excellentElect 0.001～20000mg/kg as, more preferably 0.1～1000mg/kg, more preferably 1～100mg/kg, most preferably be 20～40mg/kg。
In the present invention, described feed is cultivated animals feed, described cultivated animals preferably include pig, chicken, fish, duck, goose,Cat, dog, ermine, sheep, ox, shrimp, scallop, snake, soft-shelled turtle, tortoise, rabbit, deer or fox; More preferably pig, chicken, fish, duck, goose, cat, dog, ermine,Sheep, ox, shrimp, scallop or snake; More preferably pig, chicken, fish, duck, goose, cat or dog, most preferably is pig, chicken, fish or duck. At thisIn bright, described feed can be the feed of the different growth phases of cultivated animals, as newborn piglet 0～15kg stage, piggy 15～60kg stage or farrowing sow stage.
In the present invention, described feed can be newborn concentrated feed for piglet. In the present invention, described newborn concentrated feed for pigletCan be 21～60 age in days breast concentrated feed for piglet, comprise: dregs of beans, fish meal, whey powder, mineral mcg vitamin premix and 2,4-resacetophenone. In the present invention, the quality of described 2,4-dihydroxyacetophenone in age in days breast concentrated feed for piglet containsAmount can be 2500mg/Kg～3500mg/Kg, can also be 2800mg/Kg～3200mg/Kg, can be also 3000mg/Kg.
In the present invention, described feed can also be the premix of newborn piglet mine trace element. In the present invention, described breastThe premix of piglet mine trace element can be the newborn piglet mine trace element premix of 21～60 ages in days. In the present invention,The premix of breast piglet mine trace element can comprise CuSO4·5H2O, zinc oxide, FeSO4·H2O, ferrous fumarate,MnSO4·H2O、KI、NaSeO3, stone flour, calcium monohydrogen phosphate, salt, FE-5, methionine, tryptophan, threonine, chlorinationCholine and 2,4-dihydroxyacetophenone. In the present invention, described 2,4-dihydroxyacetophenone is pre-at newborn piglet mine trace elementMass content in batch mixing can be 1000mg/Kg～1500mg/Kg, can also be 1200mg/Kg～1300mg/Kg, also canThink 1250mg/Kg.
In the present invention, described feed can be albumin milk pig customized feed. In the present invention, described high protein sucking pigCustomized feed can comprise FE-5, fish meal, whey powder and 2,4-dihydroxyacetophenone. In the present invention, described 2,The mass content of 4-resacetophenone in high protein sucking pig customized feed can be 15000mg/Kg～25000mg/Kg, alsoCan be 18000mg/Kg～22000mg/Kg, can be also 20000mg/Kg.
In the present invention, described feed addictive can add in the basal diet of feeding animals. The present invention is to describedThe composition of feeding animals basal diet does not have special restriction, and those skilled in the art can select to close according to different cultivated animalsThe basal diet composition becoming is to meet the requirements of trophic level.
In the present invention, described basal diet can be the basal diet of pig. In the present invention, the basal diet of described pigCan comprise corn, dregs of beans, wheat bran, fish meal, CaCO3、CaHPO3, salt and premix. In the present invention, described premix canTo comprise: the Cu of 200ppm～300ppm, the Fe of 200ppm～300ppm, the Zn of 150ppm～250ppm, 50ppm～70ppmMn, the I of 0.2ppm～0.4ppm, the Se of 0.2ppm～0.4ppm, the Vitamin of 250ppm～350ppm, 800ppm～The choline of 1200ppm. In the present invention, the addition of described feed addictive in the basal diet of pig can be 20ppm～40ppm。
In the present invention, described basal diet can be also sow diets. In the present invention, described sow diets can wrapDraw together corn, wheat bran, Soybean Meal, fish meal, golden fat soybean, soya-bean oil, FE-5, calcium monohydrogen phosphate, calcium carbonate, Choline Chloride,China's multidimensional, salt and trace element. In the present invention, the addition of described feed addictive in sow diets can be400ppm～600ppm。
In the present invention, described 2,4-dihydroxyacetophenone is mainly by promoting erythrocytic function of carrying oxygen, improving bloodLiquid circulation, accelerates the metabolism of animal, accelerates the development growth of animal, thereby reaches the effect that improves daily gain and food conversionThe effect of rate is a kind of physiological, natural growth promoter. And olaquindox of the prior art, quinocetone, many, the second of quinoline matchOxygen first quinoline, nitrophenols sodium, carbadox are mainly growth and the feed efficiencies by the inhibition of pathogenic microorganism being promoted to animalRaising. Having bibliographical information olaquindox still to have protein assimilation, is a kind of parahormone sample stimulating animal growth and feed effectThe promoter of the raising of rate, but hormone and hormonelike function in feed because its side effect is prohibited more conventionally. At thisIn invention, 2,4-dihydroxyacetophenone is grown as the alternative harmful feed existing or that forbidden of the short long agent of feed growthPromoter is as carbadox, olaquindox, arsanilic acid, Roxarsone, quinocetone, methylamino ethoxy quinoline (LIJUNJING), nitrophenols sodium, quinoline matchMany.
In the present invention, described 2,4-dihydroxyacetophenone is the red function of taking by improving erythrocyte, promotes blood redThe deformability of cell, thus the penetrating ability of enhancing capillary wall is improved microcirculation, takes like this oxygen more, and blood is fresherRed, haemocyte deformation coefficient enlarges markedly, and quickly by capillary wall, microcirculation is more unobstructed, active, makes newborn piglet skinPresent the natural, gratifying ruddy of a kind of general. And arsanilic acid of the prior art, Roxarsone are organic arsenic preparations, itStrengthen devastatingly the permeability of capillary, be a kind of pathologic fur glow, thereby be local, patchinessRed, focus mostly at belly, four limbs flank portion, femoribus internus and the neck root of piglet, this ruddy commodity is not strong. The present invention carriesThe 2,4-dihydroxyacetophenone of confession promotes newborn piglet fur glow merit alternative by forbidding or forbidden as feed addictiveFeed addictive arsenic preparation (arsanilic acid, Roxarsone).
Embodiment 1
Take purity and be 99% 2,4-dihydroxyacetophenone 300Kg, cornstarch 1200Kg, at the stainless steel of 2000LIn double-shaft horizontal mixer, mix and (before mixing, measure mixture homogeneity coefficient of variation CV≤5% of this mixer, meet and raiseThe production requirement of feed additives), be mixed with 2,4-dihydroxyacetophenone mass fraction and be 20% feed addictive.
Embodiment 2
Take purity and be 99% 2,4-dihydroxyacetophenone 180Kg, ferrous fumarate 820Kg, at the stainless steel of 2000LIn cone-type mixer, mix and (mix front mixture homogeneity coefficient of variation CV≤5% of measuring this mixer, meet feed and addAdd the production requirement of agent), be mixed with 2,4-dihydroxyacetophenone mass content and be 18% feed addictive.
Embodiment 3
Taking purity is 99% 2,4-dihydroxyacetophenone 500Kg, the FE-5 that purity is 98.5%500Kg mixes and (before mixing, measures the mixture homogeneity variation of this mixer in stainless steel " V " the shape mixer of 2000LCoefficient CV≤5%, meets the production requirement of feed addictive), be mixed with 2,4-dihydroxyacetophenone mass content and be 50%Feed addictive.
Embodiment 4
With dregs of beans 650Kg, fish meal 30Kg, (high protein) whey powder 119.7Kg, mineral mcg vitamin premix 200KgBe mixed with the concentrated feeds of 20% 21～60 ages in days breasts piglets with the 2,4-dihydroxyacetophenone of 0.3Kg, in described feed 2,The mass content of 4-resacetophenone is 3000mg/Kg.
Embodiment 5
With the CuSO of 20Kg4·5H2The zinc oxide of O, 75Kg, the FeSO of 125Kg4·H2The ferrous fumarate of O, 66.7KgThe MnSO of (iron content 30%), 15Kg4·H2The KI of O, 0.006Kg, the NaSeO of 0.0015Kg3, the stone flour of 261.7925Kg, 88KgCalcium monohydrogen phosphate, the salt of 9.25Kg, the FE-5 of 200Kg, the methionine of 75Kg, the tryptophan of 0.5Kg, 2.5KgThreonine, the Choline Chloride of 60Kg and the 2,4-dihydroxyacetophenone of 1.25Kg be mixed with the breast son of 4% 21～60 ages in daysPig mine trace element premix 1000kg, in described feed, the mass content of 2,4-dihydroxyacetophenone is 1250mg/Kg.
Embodiment 6
With (high protein) whey powder of the FE-5 of 250Kg, the import of 350Kg (Peru) fish meal, 380Kg andThe 2,4-dihydroxyacetophenone of 200Kg is mixed with high protein sucking pig customized feed, 2,4-dihydroxyacetophenone in described feedMass content is 20000mg/Kg.
Embodiment 7
120 of assorted boars of binary choosing about 27Kg, are divided into four groups, every group of 3 repetitions, five of each repetitions, test 1Group is added the feed addictive that 100g embodiment 1 prepares in basal diet per ton, tests 2 groups in basal diet per tonAdd the feed addictive that 200g embodiment 1 prepares, test 3 groups of carbadoxs that add 50g in basal diet per ton, examinationTest 4 groups of olaquindoxs that add 100g in basal diet per ton, test 5 groups of nitrophenols that add 50g in basal diet per tonSodium, tests 6 groups of quinocetones that add 150g in basal diet per ton, tests 7 groups and add 100g's in basal diet per tonQuinoline match is many; In above-mentioned each test group daily ration per ton, add again 10% colistin sulfate 200g and 20% aureomycin 300g, base simultaneouslyPlinth daily ration composition and trophic level are as shown in table 1, and table 1 is composition and the trophic level of basal diet in the embodiment of the present invention 7.
The composition of basal diet and trophic level in table 1 embodiment of the present invention 7
Premix (ppm of unit):
Cu:250Fe:240Zn:180Mn:60I:0.3
Se:0.03 choline 1000Vit (compound)
Test adopts ground flat foster, free choice feeding, and each group is all the same, feeds 37 days, and test performance result is as shown in table 2,Table 2 is the embodiment of the present invention 7 the performance test results, and wherein the method for testing of skin colourity is: according to the skin color of pig, make" brilliant day " colorimetric card of 1～7 Different Red polishing degree, the same position of each buttocks with " brilliant day " colorimetric card and each pig entersRow relatively, obtains chromatic value and is weighted on average, and the weighted average of acquisition is the ruddy degree of skin of each test group piglet.The ruddy degree of skin of piglet is the sensory evaluation project of a very important commodity piglet, it is generally acknowledged the ruddy happiness of piglet skinPeople, health and the growth potential of pig are better, thus the selling price of piglet is higher, and ochrodermia is malnutritive and have a disease oftenMay, certainly extremely popular is that disease enters blind the accusing of of cream.
Table 2 embodiment of the present invention 7 the performance test results
| Test group | Beginning counterpoise kg | End counterpoise kg | Daily gain g | Daily ingestion amount g | Feedstuff-meat ratio | Skin colourity |
| 1 | 27.38±1.87 | 51.95±2.32 | 664±15a | 1394 | 2.10a | 5.56±0.62ab |
| 2 | 27.33±2.25 | 50.38±3.43 | 623±36a | 1414 | 2.27a | 6.17±0.86a |
| 3 | 27.43±1.35 | 51.59±0.98 | 653±32.13a | 1425 | 2.18a | 3.85±0.73c 5 --> |
| 4 | 27.65±1.08 | 51.24±3.65 | 639±36.35a | 1310 | 2.05a | 4.65±0.65 |
| 5 | 27.60±0.53 | 52.61±3.72 | 676±30.56a | 1345 | 1.99a | 6.35±0.66ab |
| 6 | 27.25±1.30 | 50.63±1.9 | 632±15.36a | 1397 | 2.21a | 3.13±0.95c |
| 7 | 26.38±1.80 | 50.58±3.6 | 654±37.21a | 1328 | 2.03a | 3.63±0.72c |
As shown in Table 2,2,4-dihydroxyacetophenone be added to 20ppm (test group 1) than add 40ppm (test group 2) exist25～60kg stage is effective; Add 20ppm and organize its daily gain and feedstuff-meat ratio and carbadox, olaquindox, nitrophenols sodium, quinoline alkeneKetone, the how each group of quinoline match do not have significant difference, prove that 2,4-dihydroxyacetophenone can substitute these growth promoters completely, noOnly toxicity is very little, and addition is very low. 2,4-dihydroxyacetophenone addition 20ppm, 40ppm group pig the ruddy degree of fur withOther each group all has significant difference, has added the ruddy Du Gengjia of fur of the test group pig of 2,4-dihydroxyacetophenone.
Embodiment 8
40 of assorted boars of binary choosing about 25Kg, are divided into four groups, every group of 1 repetition, and 5 of each repetitions, test 1 groupIn basal diet, add the feed addictive that 100g/ ton embodiment 1 prepares, test 2 groups and add in basal dietThe feed addictive that 200g/ ton embodiment 1 prepares, tests 3 groups of carbadoxs that add 50g/ ton in basal diet, test4 groups are added the olaquindox of 100g/ ton in basal diet, test 5 groups of nitrophenols sodium that add 50g/ ton in basal diet, examinationTest 6 groups of quinocetones that add 150g/ ton in basal diet, test 7 groups of quinoline matches of adding 100g/ ton in basal diet many,Identical with embodiment 7 of the composition of basal diet and trophic level added in above-mentioned each test group daily ration per ton simultaneously again10% colistin sulfate 200g and 20% aureomycin 300g.
Feeding and management is consistent with embodiment 7, carries out after 15 days, with confirming to infect the dead of blue otopathy poison and the disease of breathing in testThe gastric content of pig mixes with the expanded corn powder of 16Kg, and 2Kg is thrown on the every hurdle of each test group, continues test 30 days, asFruit morbidity, treatment routinely, test performance result is as shown in table 3, and table 3 is the embodiment of the present invention 8 the performance test results, Qi ZhongpiThe method of testing of colour of skin degree is consistent with embodiment 7.
Table 3 embodiment of the present invention 8 the performance test results
As shown in Table 3, in the time being subject to disease infringement, 2,4-dihydroxyacetophenone test group all shows good opposing diseaseSick supporting capacity, although there is morbidity, does not have dead appearance yet, though its daily gain and material meat are pessimistic, obviously than kappaThe group such as oxygen is much better, and wherein best to add 40ppm (test group 2) effect, its daily gain level is than carbadox, olaquindox, nitreBase phenol sodium, that quinocetone, quinoline match multicomponent be you can well imagine is high by 31.0%, 42.0%, 69.57%, 55.03%, 64.78%, proves 2,4-Resacetophenone newborn piglet suffer stress or disease conditions under show the excellent basic production performance that watches for animalsAbility.
Embodiment 9
Choose 30 of three parity multiparity lactations (long × large) sows, every sow all farrows 12, and sow is divided into three at randomGroup, 10 every group, establish control group, control group fed sow diets, tests 1 group and in sow diets, adds the 2000g/ embodiment that pauses1 feed addictive preparing, tests 2 groups and in sow diets, adds the 3000g/ feed that embodiment 1 prepares that pauses and addAdd agent, composition and the trophic level of sow diets are as shown in table 4, and table 4 is composition and the battalion of sow diets in the embodiment of the present invention 9The level of supporting. When wean on the 21st, test performance result is as shown in table 5, and table 5 is the embodiment of the present invention 9 the performance test results, Qi ZhongpiThe method of testing of colour of skin degree is consistent with embodiment 7.
The composition of sow diets and trophic level in table 4 embodiment of the present invention 9
| Composition | Content (%) | Trophic level |
| Corn | 54 | Digestibility 14.2075mj/kg |
| Wheat bran | 54 | Crude protein 18.2630% |
| Soybean Meal | 11 | Ca 0.7155％ |
| Fish meal | 3 | Available phosphorus 0.5675% |
| Gold fat soybean | 9 | Lysine 0.9461% |
| Soya-bean oil | 4 | Egg+cystine 0.7855 |
| FE-5 | 0.09 | |
| Calcium monohydrogen phosphate | 2.2 | |
| Calcium carbonate | 0.2 | |
| Choline Chloride | 0.25 | |
| China's multidimensional 1 type | 0.04 | |
| Salt | 0.25 | |
| Trace element | 1 | |
| Add up to | 100 |
Table 5 embodiment of the present invention 9 the performance test results
| Birth weight kg | Weaning weight g on the 21st | Daily gain g | Skin colourity | Survival rate (%) | |
| Control group | 1.30±0.15 | 6.75±0.81 | 259.5 | 4.61±0.35 | 95 |
| Test 1 group | 1.29±0.16 | 7.25±0.31 | 283.8 | 6.56±0.29 | 100 |
| Test 2 groups | 1.28±0.19 | 7.38±0.43 | 290.5 | 6.78±0.26 | 100 |
As shown in Table 5, interpolation 2,4-dihydroxyacetophenone has obviously improved the survival rate of suckling pig, and the ruddy degree of skin alsoSignificantly be better than control group, add 400ppm (test group 1), 600ppm (test group 2), 21 age in days weaning weights are carried than control group respectivelyHigh by 7.41%, 9.33%.
Embodiment 10
Choose multiparity two tire sows, 30 of in-pigs, are divided into three groups, set up blank group separately, control group fed basisDaily ration, tests 1 group and in basal diet, adds the feed addictive that 1500 grams/embodiment 1 prepare, and tests 2 groups at baseIn plinth daily ration, add the feed addictive that 3000 grams/embodiment 1 prepare, basal diet formula is as shown in table 6, and table 6 isBasal diet formula in the embodiment of the present invention 10.
Basal diet formula in table 6 embodiment of the present invention 10
| The conceived stage | Corn % | Wheat bran % | Dregs of beans % | Premix % |
| Conceived 10-77 days | 62 | 21 | 13 | 4 |
| Conceived 77-107 days | 63 | 16 | 17 | 4 |
| Lactating sow to be produced produces the last week | 67 | 9 | 20 | 4 |
Test each group of litter size, stillborn foetus number, birth weight as shown in table 7, table 7 is the embodiment of the present invention 10 performance tests knotsReally.
Table 7 embodiment of the present invention 10 the performance test results
| Test group | Litter size/head | Nascent counterpoise/gram | Stillborn foetus sum/head | Weak tire number/head |
| Control group | 11.6 | 1180±95 | 4 | 6 |
| 1 | 11.9 | 1290±53 | 1 | 2 |
| 2 | 12.0 | 1320±36 | 0 | 1 |
As shown in Table 7, add after 2,4-dihydroxyacetophenone, piglet birth weight significantly improves, and the uniformity also obviously promotes,The weak tire number of stillborn foetus reduces, and average litter size improves 0.4.
As seen from the above embodiment, the invention provides a kind of feed addictive, comprise 2,4-dihydroxyacetophenone. The present inventionAdopt 2,4-dihydroxyacetophenone as feed addictive, it has the growth promotion and the raising feed that are not less than olaquindox in feedThe effect of conversion ratio, raising condition is poorer, and trophic level is lower, and effect is more obvious; And it also has organic female system that is superior toAgent causes the effect of pigskin hair glow; 2,4-dihydroxyacetophenone is the substitute that olaquindox and organic arsenic preparation are good, is onePlant the good growth promotion animal feed additive having no side effect.
Above-described is only the preferred embodiment of the present invention, it should be pointed out that the ordinary skill for the artPersonnel, under the premise without departing from the principles of the invention, can also make some improvements and modifications, and these improvements and modifications alsoShould be considered as protection scope of the present invention.
Claims (10)
1. a feed addictive, comprises 2,4-dihydroxyacetophenone.
2. feed addictive according to claim 1, is characterized in that, described feed addictive also comprises diluent.
3. feed addictive according to claim 2, is characterized in that, described diluent comprises soy meal, corn flour, littleFlour, fish meal, meat meal tankage, sorghum flour, starch, wheat bran, rice bran, paddy meal, assorted dregs of rice powder, stone flour, ferrous fumarate, sulfuric acid AsiaIron, calcium monohydrogen phosphate, calcium formate, manganese sulfate, zinc oxide, zeolite powder, medical stone powder, sepiolite powder, lysine, threonine and egg ammoniaOne or more in acid.
4. feed addictive according to claim 2, is characterized in that, described 2,4-dihydroxyacetophenone and diluentMass ratio is 100:(0.001～100000).
5. feed addictive according to claim 4, is characterized in that, described 2,4-dihydroxyacetophenone and diluentMass ratio is 100:(0.1～1000).
6. a feed, comprises the feed addictive described in any one in claim 1～5.
7. feed according to claim 6, is characterized in that, the quality of described 2,4-dihydroxyacetophenone in feed containsAmount is 0.0001%～20%.
8. feed according to claim 6, is characterized in that, the form of described feed comprise mixed fodder, mixed feed,Concentrated feed, mine trace element premixed feed, vitamin premixed feed, mine trace element vitamin compound premixingOne in material, powered milk substitute class feed, customization premixed feed, customized feed, customization pharmaceutical feed and customized feed additiveOr several.
9. feed according to claim 6, is characterized in that, the feed that described feed is cultivated animals, and described cultivation is movingThing comprises pig, chicken, fish, duck, goose, cat, dog, ermine, sheep, ox, shrimp, scallop, snake, soft-shelled turtle, tortoise, rabbit, deer or fox.
10. feed according to claim 9, is characterized in that, described feed is raising of the different growth phases of cultivated animalsMaterial.
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