CN105641550A

CN105641550A - Traditional Chinese medicine composition for treating asthma

Info

Publication number: CN105641550A
Application number: CN201610093591.0A
Authority: CN
Inventors: 覃淑兰
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-02-19
Filing date: 2016-02-19
Publication date: 2016-06-08

Abstract

The invention relates to traditional Chinese medicine composition for treating asthma and belongs to the technical field of medicines. The traditional Chinese medicine composition comprises raw materials in parts by weight as follows: 10-15 parts of black medic herbs, 9-18 parts of rockspray, 12-18 parts of gerbera, 3-10 parts of belleric terminalia fruits, 13-19 parts of paulownia fruits, 9-15 parts of marsdenia tenacissima, 5-10 parts of henbane seeds, 10-15 parts of cymbidium ensifolium roots, 2-7 parts of tangerine pith, 6-12 parts of Argyreia acuta Lour, 10-20 parts of coix seeds, 3-9 parts of ginseng leaves, 9-12 parts of snakegourd peel, 6-12 parts of Indian damnacanthus herbs, 9-15 parts of roots of Rosthorn Bigginseng and 6-15 parts of fructus psoraleae. The traditional Chinese medicine composition has functions of clearing heat, promoting diuresis, moistening the lungs, relieving sore-throat, eliminating phlegm, stopping cough, regulating qi, dispelling wind, removing dampness, tonifying the spleen, tonifying the kidneys and the like and can be widely applied to preparation of arteriosclerosis treatment drugs, further, the curative effect is remarkable, no relapse occurs after healing, toxic and side effects are avoided, and the safety is high.

Description

A kind of Chinese medicine composition treating asthma

[technical field]

The present invention relates to pharmaceutical technology field, especially a kind of Chinese medicine composition treating asthma.

[technical background]

Asthma is a kind of commonly encountered diseases, frequently-occurring disease, it it is the chronic airway inflammation participated in by various kinds of cell particularly mastocyte, eosinophilic granulocyte and T lymphocyte, in susceptible person, this kind of inflammation can cause panting of recurrent exerbation, the symptoms such as tachypnea, uncomfortable in chest and (or) cough, small number of patients is also possible to chest pain for main manifestations. In the recent decade, the national asthma prevalence such as the U.S., Britain, Australia, New Zealand and mortality rate are on the rise, and the whole world there are about 100,000,000 asthmatic patients, it has also become a kind of major chronic illnesses of serious threat public health.

The pathogenesis of asthma includes: allergy, chronic airway inflammation, airway hyperreactivity, air flue neuroregulation are not normal, genetic mechanism, respiratory virus infection, neuronal signals transduction machine-processed and airway remodeling and interaction etc. thereof. Acute attack stage, chronic sustained phase and clinical relieving period can be divided into according to clinical manifestation asthma. Asthma in acute attack refer to pant, tachypnea, cough, the symptom such as uncomfortable in chest occur suddenly, or original symptom sharp deterioration, often have dyspnea, be reduced to its feature with expiratory gas flow, often because contact allergen, stimulus object or respiratory tract infection are brought out; The chronic sustained phase refers to weekly all different frequency and (or) occurs symptom (pant, out of breath, uncomfortable in chest, cough etc.) to some extent; Clinical relieving period means and disappears through treatment or untreated symptom, sign, and pulmonary function returns to level before acute attack, and maintains more than 3 months. If asthmatic patient occurs that serious acute shows effect, it is likely to fatal when giving treatment to not in time. Control not good asthmatic patient routine work and daily life all can be made a difference, may result in and delay work, learn by mistake, cause activity, limitation of movement, make quality of life decline, and bring burden economically and the life generation negative effect to household. And asthma recurrent exerbation also can result in the complication such as chronic obstructive pulmonary disease, emphysema, pulmonary heart disease, heart failure, respiratory failure.

At present, adopting Chinese and Western combination the treatment of asthma more, its medicine many employings aminophylline, ephedrine, diphenhydramine and antibiotics etc., though these medicines can play mitigation for the moment, but great majority all can not be treated for the pathogenic factor of asthma, cures the symptoms, not the disease, easily recurs after drug withdrawal, and some medicine has bigger side effect, it is impossible to long-term taking;Conventional Chinese patent medicine capsule of antipyretics for lung, Bulbus Fritillariae Cirrhosae sheet etc., side effect is little, but slow curative effect, the course for the treatment of is long, and actual therapeutic effect is not fairly obvious. Therefore treat, in the urgent need to a kind of, the medicine that the asthma time limit is short, curative effect is high, rate is low repeatedly at present.

[summary of the invention]

For posed problems above, the invention provides a kind of Chinese medicine composition treating asthma, this Chinese medicine composition is used for treating asthma effect significantly, and short treating period, curative effect is high, controls difficulty in relapse after healing, and has no side effect, takes safety.

In order to realize above-mentioned purpose, the technical solution adopted in the present invention is:

A kind of Chinese medicine composition treating asthma, it includes the raw material of following weight portion: Herba Medicaginis Lupulinae 10-15 part, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 9-18 part, Herba Leibnitziae 12-18 part, Fructus Terminaliae Billericae 3-10 part, Fructus Paulowniae 13-19 part, Caulis Marsdeniae Tenacissimae 9-15 part, Semen Hyoscyami 5-10 part, orchid root 10-15 part, Vascular aurantii 2-7 part, Cortex Hibisci 6-12 part, Semen Coicis 10-20 part, Folium Ginseng 3-9 part, Pericarpium Trichosanthis 9-12 part, Herba Damnacanthi 6-12 part, Radix Macropanacis Rosthornii 9-15 part, Fructus Psoraleae 6-15 part.

Further, described Chinese medicine composition includes the raw material of following weight portion: Herba Medicaginis Lupulinae 12-14 part, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 12-16 part, Herba Leibnitziae 14-16 part, Fructus Terminaliae Billericae 5-7 part, Fructus Paulowniae 15-17 part, Caulis Marsdeniae Tenacissimae 11-13 part, Semen Hyoscyami 7-9 part, orchid root 11-13 part, Vascular aurantii 4-6 part, Cortex Hibisci 8-10 part, Semen Coicis 13-17 part, Folium Ginseng 5-7 part, Pericarpium Trichosanthis 10-11 part, Herba Damnacanthi 8-10 part, Radix Macropanacis Rosthornii 11-13 part, Fructus Psoraleae 8-12 part.

Further, described Chinese medicine composition includes the raw material of following weight portion: Herba Medicaginis Lupulinae 13 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 14 parts, Herba Leibnitziae 15 parts, Fructus Terminaliae Billericae 6 parts, Fructus Paulowniae 16 parts, Caulis Marsdeniae Tenacissimae 12 parts, Semen Hyoscyami 8 parts, orchid root 12 parts, Vascular aurantii 5 parts, Cortex Hibisci 9 parts, Semen Coicis 15 parts, Folium Ginseng 6 parts, Pericarpium Trichosanthis 10 parts, Herba Damnacanthi 9 parts, Radix Macropanacis Rosthornii 12 parts, Fructus Psoraleae 10 parts.

Further, the preparation method of described Chinese medicine composition comprises the following steps:

1) described raw material is picked according to above-mentioned weight portion;

2) by step 1) raw material that takes cleans after drying, break and be broken to length less than 1cm, it is mixed and puts in pot, adding the water of raw material gross weight 6-8 times, soak 2-3h, intense fire turns slow fire boiling 40-60min after boiling, filter to obtain medicinal residues I and medicinal liquid I, and backward medicinal residues I add the water of material medicine gross weight 3-5 times, intense fire turns slow fire boiling 20-40min after boiling, filter to obtain medicinal liquid II;

3) combining step 2) decoct gained medicinal liquid I and medicinal liquid II twice, then it is condensed into the thick paste of relative density 1.20-1.30 when 25 DEG C, get product Chinese medicine composition.

Further, described Chinese medicine composition can be applicable in the medicine of preparation treatment asthma.

Further, in the application of the medicine of preparation treatment asthma, by this area conventional formulation method, pharmaceutically acceptable adjuvant can be added in the Chinese medicine composition of effective dose of the present invention, make various conventional formulation clinically.

Further, the present invention can be made into granule, capsule, tablet or pill.

Instructions of taking: for oral administration, each takes the Chinese medicine preparation that effective dose is 1-2g, and daily 3 times, early, middle and late decoction being taken warmly half an hour after meal, 10 days is a course for the treatment of, and period of taking medicine withdraws other drug, and avoid eating anything raw or cold, pungent, the food that stimulates.

Chinese medicine details of the present invention is as follows:

Herba Medicaginis Lupulinae: for the herb of leguminous plant shamrock.Excavate herb, using fresh herb or chopping summer to dry. It is sweet puckery, and property is put down. Return lung, liver, gallbladder, kidney channel. There is effect of clearing away heat-damp and promoting diuresis, relaxing muscles and tendons and activating QI and blood in the collateral, relieving cough and asthma, removing pathogenic heat from blood and toxic substance from the body. Main jaundice due to damp-heat, pyretic stranguria, jaundice due to damp-heat, pyretic stranguria, stranguria caused by urinary stone, rheumatic arthralgia, cough with asthma, hemorrhoidal bleeding, finger furuncle, venom.

Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis): for branch and leaf or the root of the flat Fructus Gardeniae of rosaceous plant. Sour in the mouth, puckery, cool in nature. Return lung, Liver Channel. There is effect of clearing away heat-damp and promoting diuresis, preventing phlegm from forming and stopping coughing, hemostasis and pain-relieving. Main dysentery, has loose bowels, stomachache, and cough is spitted blood, dysmenorrhea, leucorrhea.

Herba Leibnitziae: for herb or the whole herb with root of feverfew Herba Leibnitziae. Bitter in the mouth, cold in nature. There is effect of clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling. Main cough due to lung-heat, damp-heat dysentery, pyretic stranguria, rheumatic arthritis, carbuncle furuncle and phyma poison, ecthyma, venom, burn and scald, traumatic hemorrhage.

Fructus Terminaliae Billericae: adjoin the dry mature fruit of Li Le for Combretum Racemosum plant. Sweet in the mouth, puckery, property is put down. There is effect of heat-clearing and toxic substances removing, sore-throat relieving, cough-relieving dysentery relieving, nourishing blood and hemoslasis. Main laryngopharynx swelling and pain, cough, dysentery, bleeding hemorrhoids, grasserie, metrorrhagia, body is empty after being ill.

Fructus Paulowniae: for the fruit of goatweed Paulownia or royal paulownia. Bitter in the mouth, cold nature. Have reduce phlegm, cough-relieving, effect of relievining asthma. Main chronic bronchitis, cough is coughed up phlegm.

Caulis Marsdeniae Tenacissimae: for the rattan of trailing plants section plant Caulis Marsdeniae Tenacissimae, root or leaf. Bitter in the mouth, cold nature. Return lung, Liver Channel. There is effect of heat-clearing and toxic substances removing, relieving cough and asthma. Control pneumonia, bronchitis, bronchial asthma, pharyngolaryngitis, tonsillitis, cystitis, treat pyogenic infections from tumour or sore.

Semen Hyoscyami: for the dry body of Ju Yin section animal Pheretima aspergillum, popular Pheretimatschiliensis, power simulation or the blind Pheretimatschiliensis of comb. Taste salty in the mouth, cold in nature. Return liver, spleen, bladder warp. There is effect of clear gesture relieving convulsion, suppressing the hyperactive liver to relieve the wind syndrome, dredge the meridian passage, diuresis of relievining asthma. The heating of main calentura is mad dry, and infantile convulsion is twitched, headache due to hyperactivity of liver-YANG, apoplectic hemiplegia, rheumatic arthralgia, dyspnea and cough due to lung-heat, urinary obstruction.

Orchid root: for the root that orchid sword-leaved cymbidium, orchid, Cymbidium Kanran Mak. or platform are blue. Acrid in the mouth, property is put down. There is nourishing the lung to arrest cough, clearing away heat-damp and promoting diuresis, regulate the flow of vital energy, effect of promoting blood circulation and hemostasis, removing toxic substances parasite killing. Main hemoptysis of pulmonary tuberculosis, pertussis, acute gastroenteritis, pyretic stranguria, leukorrhagia, nebulousurine, menoxenia, metrorrhagia, to have blood in stool, traumatic injury, furuncle toxic swelling, hemorrhoid, ascarid is suffered from abdominal pain, lyssodexis.

Vascular aurantii: for the grain of the peel internal layer of the multiple Fructus Citri tangerinae classes such as rutaceae tangerine produced in fujian province or Zhu's Fructus Citri tangerinae. Sweet in the mouth, hardship, property is put down. Return liver, spleen channel. The effect have dredging collateral, regulate the flow of vital energy, reducing phlegm, controls blockage of meridian-QI, chronic cough chest pain, sputum mixed with blood, gets sick from drinking too much wine thirsty. " detailed outline is picked up any lost article from the road ": the stagnant gas of the meridian dredging, vessel-distension, drives flesh side film apposition expectorant, invigorates blood circulation. " book on Chinese herbal medicine asks former ": the meridian dredging, has a respite, reduces phlegm, and dry stomach goes dirty, and blood vessels. " Traditional Chinese Medicine in Sichuan will ": eleminating phlegm and freeing channels, controls impairment of the lung caused by overstrain expectoration, hemoptysis and damp and hot visitor in through diseases such as tunnels.

Cortex Hibisci: for the stem and leaf of convolvulaceous plant Caulis et Folium Argyreia eacutae. Bitter in the mouth is pungent, cool in nature. There is effect of preventing phlegm from forming and stopping coughing, regulating blood circulation to dispel wind pathogen. Control heat syndrome cough, phlegm dyspnea, spit blood, metrorrhagia, leucorrhea, traumatic injury, rheumatalgia, sore. " register planted by Guangxi medicine ": expectorant, lung moistening, cough-relieving, hemostasis. Control pulmonary tuberculosis, acute mastitis, burn due to hot liquid or fire. " mountain of papers Chinese herbal medicine ": relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and removing dampness, relieving cough and resolving phlegm, regulating menstruation, hemostasis. Control traumatic injury, rheumatalgia, acute/chronic bronchitis.

Semen Coicis: for the kernel of grass Semen Coicis.Sweet in the mouth, light; Cold nature. Return spleen, lung, kidney channel. There is effect of spleen invigorating, tonifying the lung, heat clearing away, dampness removing. Control and have loose bowels, arthralgia chiefly caused by damp pathogen, muscle arteries and veins contracture, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea.

Folium Ginseng: for the dried leaves of Araliaceae Radix Ginseng. Bitter in the mouth, sweet, cold in nature. Attach to the lung and stomach meridians. There is QI invigorating, lung benefiting, effect of driving away summer heat, promoting the production of body fluid. For qi-asthenia cough, summer-heat is irritated, and Tianjin wound is thirsty, and the head is unclear, and extremity are tired weary.

Pericarpium Trichosanthis: for the dry mature skin of cucurbitaceous plant Fructus Trichosanthis or trichosanthes rosthornii Harms. Sweet in the mouth, cold in nature. Attach to the lung and stomach meridians. There is effect of moistening the lung and resolving phlegm, promoting the circulation of QI the chest stuffiness relieving. Control phlegm-heat cough, pharyngalgia, chest pain, spit blood, epistaxis, quench one's thirst, constipation, ulcerative carbuncle toxic swelling. " Records of Tradition Chinese and Western Medicine in Combination ": lung heat clearing, astringes the lung, relieving coughing, Dingchuan. " Chinese medicinal herbal ": clearing away phlegm is tied, and soothing liver-QI is strongly fragrant. Controlling phlegm-heat cough, the breast side of body is had a pain. " Traditional Chinese Medicine in Sichuan will ": lung moistening sending down the abnormal ascending QI, eliminating phlegm and stopping cough. Control and have sore throat, constipation due to dry stool and acute mastitis.

Herba Damnacanthi: for herb or the root of Maguireothamnus speciosus Herba Damnacanthi. Bitter but sweet flavor, property is put down. There is effect of expelling wind and removing dampness, promoting blood circulation and detumescence. Control gout, rheumatic arthralgia, cough due to fluid-retention, lung abscess, edema, mass in the abdomen, jaundice, women's amenorrhea, infantile malnutrition, urticaria, traumatic injury.

Radix Macropanacis Rosthornii: sweet in the mouth, property is put down. There is effect of expelling wind and removing dampness, disperse blood stasis and dredge collateral, spleen invigorating. Main air pain of dampness syndrome, traumatic injury wound is swollen, fracture, infantile malnutrition.

Fructus Psoraleae: for the fruit of legumes psoraleae. Acrid in the mouth, hardship, warm in nature. Return kidney channel, pericardium channel, spleen channel, stomach warp, lung meridian. There is effect of reinforcing the kidney and supporting YANG. Controlling cold diarrhea of suffering from a deficiency of the kidney, the enuresis, spermatorrhea, frequent micturition, sexual impotence, chills and pain of the waist and kness, deficiency and coldness is breathed heavily and is coughed. External curing vitiligo.

The invention provides a kind of Chinese medicine composition treating asthma, compared with prior art, have the advantages that

The Chinese medicine composition for the treatment of asthma provided by the present invention makes up a prescription according to the curative mechanism of asthma, with Herba Medicaginis Lupulinae, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis), Herba Leibnitziae, Fructus Terminaliae Billericae, Fructus Paulowniae, Caulis Marsdeniae Tenacissimae, Semen Hyoscyami, orchid root, Vascular aurantii, Cortex Hibisci, Semen Coicis, Folium Ginseng, Pericarpium Trichosanthis, Herba Damnacanthi, Radix Macropanacis Rosthornii, Fructus Psoraleae for primary raw material, wherein Herba Medicaginis Lupulinae, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis), Herba Leibnitziae can clearing away heat-damp and promoting diuresis, removing toxic substances, relieving cough and asthma; Fructus Terminaliae Billericae smooth throat to stop cough; Fructus Paulowniae, Caulis Marsdeniae Tenacissimae, Semen Hyoscyami can reduce phlegm, cough-relieving, relieving asthma, suppressing the hyperactive liver to relieve the wind syndrome; Orchid root, Vascular aurantii have the effect of nourishing the lung to arrest cough, activating QI to eliminate phlegm, clearing away heat-damp and promoting diuresis; Cortex Hibisci, Folium Ginseng, Pericarpium Trichosanthis can lung moistening expectorants; Herba Damnacanthi expelling wind and removing dampness; Semen Coicis, Radix Macropanacis Rosthornii, Fructus Psoraleae can kidney and spleen invigoratings. All medicine compatibilities above, bring out the best in each other, play clearing away heat-damp and promoting diuresis, moistening lung and nourishing throat, preventing phlegm from forming and stopping coughing altogether, regulate the flow of vital energy dispel the wind, the effect such as strengthening spleen, tonifying kidney, physical function can be regulated on the whole, fundamentally treat asthma, evident in efficacy, short treating period, curative effect is high, control difficulty in relapse after healing, and the property of medicine is gentle, have no side effect, safe and reliable.

[detailed description of the invention]

The following examples can help those skilled in the art to be more completely understood by the present invention, but cannot be intended to limit the present invention in any manner.

Embodiment 1

A kind of Chinese medicine composition treating asthma, it includes the raw material of following weight portion: Herba Medicaginis Lupulinae 10 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 9 parts, Herba Leibnitziae 12 parts, Fructus Terminaliae Billericae 3 parts, Fructus Paulowniae 13 parts, Caulis Marsdeniae Tenacissimae 9 parts, Semen Hyoscyami 5 parts, orchid root 10 parts, Vascular aurantii 2 parts, Cortex Hibisci 6 parts, Semen Coicis 10 parts, Folium Ginseng 3 parts, Pericarpium Trichosanthis 9 parts, Herba Damnacanthi 6 parts, Radix Macropanacis Rosthornii 9 parts, Fructus Psoraleae 6 parts.Concrete preparation method comprises the following steps:

2) by step 1) raw material that takes cleans after drying, break and be broken to length less than 1cm, it is mixed and puts in pot, adding the water of raw material gross weight 6 times, soak 2h, intense fire turns slow fire boiling 40min after boiling, filter to obtain medicinal residues I and medicinal liquid I, and backward medicinal residues I add the water of material medicine gross weight 3 times, intense fire turns slow fire boiling 20min after boiling, filter to obtain medicinal liquid II;

It addition, this Chinese medicine composition can be applicable to the medicine of preparation treatment asthma, according to this field conventional formulation method, in this Chinese medicine composition, add pharmaceutically acceptable adjuvant, make various conventional formulation clinically. As: this Chinese medicine composition is carried out spray drying, then adds cane sugar powder and carboxymethylstach sodium, fully mix, then adopt wet granulation, dry, pack after granulate, make granular preparation, be packaged into bag, every bag of 6g.

Embodiment 2

A kind of Chinese medicine composition treating asthma, it includes the raw material of following weight portion: Herba Medicaginis Lupulinae 12 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 12 parts, Herba Leibnitziae 14 parts, Fructus Terminaliae Billericae 5 parts, Fructus Paulowniae 15 parts, Caulis Marsdeniae Tenacissimae 11 parts, Semen Hyoscyami 7 parts, orchid root 11 parts, Vascular aurantii 4 parts, Cortex Hibisci 8 parts, Semen Coicis 13 parts, Folium Ginseng 5 parts, Pericarpium Trichosanthis 10 parts, Herba Damnacanthi 8 parts, Radix Macropanacis Rosthornii 11 parts, Fructus Psoraleae 8 parts. Concrete preparation method comprises the following steps:

2) by step 1) raw material that takes cleans after drying, break and be broken to length less than 1cm, it is mixed and puts in pot, adding the water of raw material gross weight 6 times, soak 2h, intense fire turns slow fire boiling 50min after boiling, filter to obtain medicinal residues I and medicinal liquid I, and backward medicinal residues I add the water of material medicine gross weight 3 times, intense fire turns slow fire boiling 30min after boiling, filter to obtain medicinal liquid II;

It addition, this Chinese medicine composition can be applicable to the medicine of preparation treatment asthma, according to this field conventional formulation method, in this Chinese medicine composition, add pharmaceutically acceptable adjuvant, make various conventional formulation clinically. As: this Chinese medicine composition being carried out spray drying, then adds carboxymethylstach sodium, fully mix, then adopt wet granulation, dry, after granulate, capsule is made in fill, every 0.5g.

Embodiment 3

A kind of Chinese medicine composition treating asthma, it includes the raw material of following weight portion: Herba Medicaginis Lupulinae 13 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 14 parts, Herba Leibnitziae 15 parts, Fructus Terminaliae Billericae 6 parts, Fructus Paulowniae 16 parts, Caulis Marsdeniae Tenacissimae 12 parts, Semen Hyoscyami 8 parts, orchid root 12 parts, Vascular aurantii 5 parts, Cortex Hibisci 9 parts, Semen Coicis 15 parts, Folium Ginseng 6 parts, Pericarpium Trichosanthis 10 parts, Herba Damnacanthi 9 parts, Radix Macropanacis Rosthornii 12 parts, Fructus Psoraleae 10 parts. Concrete preparation method comprises the following steps:

2) by step 1) raw material that takes cleans after drying, break and be broken to length less than 1cm, it is mixed and puts in pot, adding the water of raw material gross weight 7 times, soak 2.5h, intense fire turns slow fire boiling 50min after boiling, filter to obtain medicinal residues I and medicinal liquid I, and backward medicinal residues I add the water of material medicine gross weight 4 times, intense fire turns slow fire boiling 30min after boiling, filter to obtain medicinal liquid II;

It addition, this Chinese medicine composition can be applicable to the medicine of preparation treatment asthma, according to this field conventional formulation method, in this Chinese medicine composition, add pharmaceutically acceptable adjuvant, make various conventional formulation clinically. As: this Chinese medicine composition being carried out spray drying, then adds carboxymethylstach sodium, fully mix, then adopt wet granulation, dry, after granulate, tablet made by tabletting, every 0.3g.

Embodiment 4

A kind of Chinese medicine composition treating asthma, it includes the raw material of following weight portion: Herba Medicaginis Lupulinae 14 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 16 parts, Herba Leibnitziae 16 parts, Fructus Terminaliae Billericae 7 parts, Fructus Paulowniae 17 parts, Caulis Marsdeniae Tenacissimae 13 parts, Semen Hyoscyami 9 parts, orchid root 13 parts, Vascular aurantii 6 parts, Cortex Hibisci 10 parts, Semen Coicis 17 parts, Folium Ginseng 7 parts, Pericarpium Trichosanthis 11 parts, Herba Damnacanthi 10 parts, Radix Macropanacis Rosthornii 13 parts, Fructus Psoraleae 12 parts. Concrete preparation method comprises the following steps:

2) by step 1) raw material that takes cleans after drying, break and be broken to length less than 1cm, it is mixed and puts in pot, adding the water of raw material gross weight 8 times, soak 3h, intense fire turns slow fire boiling 60min after boiling, filter to obtain medicinal residues I and medicinal liquid I, and backward medicinal residues I add the water of material medicine gross weight 5 times, intense fire turns slow fire boiling 40min after boiling, filter to obtain medicinal liquid II;

It addition, this Chinese medicine composition can be applicable to the medicine of preparation treatment cough, according to this field conventional formulation method, in this Chinese medicine composition, add pharmaceutically acceptable adjuvant, make various conventional formulation clinically. As: this Chinese medicine composition is carried out spray drying, then adds pure Oleum sesami or Mel mixing, deliver to and centrifugal make ball machine and make pill, every 3g.

Embodiment 5

A kind of Chinese medicine composition treating asthma, it includes the raw material of following weight portion: Herba Medicaginis Lupulinae 15 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 18 parts, Herba Leibnitziae 18 parts, Fructus Terminaliae Billericae 10 parts, Fructus Paulowniae 19 parts, Caulis Marsdeniae Tenacissimae 15 parts, Semen Hyoscyami 10 parts, orchid root 15 parts, Vascular aurantii 7 parts, Cortex Hibisci 12 parts, Semen Coicis 20 parts, Folium Ginseng 9 parts, Pericarpium Trichosanthis 12 parts, Herba Damnacanthi 12 parts, Radix Macropanacis Rosthornii 15 parts, Fructus Psoraleae 15 parts. Concrete preparation method comprises the following steps:

2) by step 1) raw material that takes cleans after drying, break and be broken to length less than 1cm, it is mixed and puts in pot, adding the water of gross weight 7 times in raw material, soak 3h, intense fire turns slow fire boiling 40min after boiling, filter to obtain medicinal residues I and medicinal liquid I, and backward medicinal residues I add the water of material medicine gross weight 4 times, intense fire turns slow fire boiling 20min after boiling, filter to obtain medicinal liquid II;

Clinical observation statistics

1, the object of observation:

Select asthmatic patient 300 example made a definite diagnosis to carry out clinical observation, cardinal symptom: during seizure of disease with cough, expectoration, pant, breathe the symptoms such as suffering, uncomfortable in chest and chest pain. It is randomly divided into treatment group and matched group, treatment group 150 example, wherein male 78 example, women 72 example, age 20-65 year, the shortest person of the course of disease 1 year, most elder 16 years; Matched group 150 example, wherein, male 76 example, women 74 example, age 18-68 year, the shortest person of the course of disease 1 year, most elder 15 years. Treatment group and the sex of two groups of cases of matched group, age, the state of an illness are basically identical, without significant difference, have comparability.

2, Therapeutic Method

Treatment group: for oral administration, each takes the Chinese medicine preparation that effective dose is 1-2g, daily 3 times, early, middle and late decoction being taken warmly half an hour after meal, 10 days is a course for the treatment of, observes after taking 2-4 the course for the treatment of, period of taking medicine withdraws other drug, and avoid eating anything raw or cold, pungent, the food that stimulates.

Matched group: the oral treatment asthmatic medicament (Singulair or terbutaline sulphate sheet etc.) bought on the market, take according to taking explanation, carrying out Synchronous with treatment group, period of taking medicine withdraws other drug, and avoid eating anything raw or cold, pungent, the food that stimulates.

4, treatment standard

Cure: symptoms of asthma, sign disappear, and follow up a case by regular visits to half a year without recidivist; Effective: symptoms of asthma substantially alleviates, and attack times reduces to some extent; Invalid: after medication, the symptoms of asthma of patient has no improvement.

5, therapeutic outcome

Treatment group and matched group clinical treatment outcome are as shown in table 1:

Table 1 treatment group and matched group clinical treatment outcome

	n	Recovery from illness	Effectively	Invalid	Total effective rate (%)
						Treatment group	150	67	72	11	92.7
Matched group	150	28	81	41	72.7

By the clinical treatment outcome of upper table 1 treatment group and matched group it can be seen that treatment group 150 example, after taking Chinese medicine decoction 2-4 the course for the treatment of that the present invention treats asthma, cure 67 examples (accounting for sum 44.7%), effective 72 examples (account for sum 48%), invalid 11 examples, total effective rate is 92.7%; Matched group 150 example, takes presently commercially available treatment asthmatic medicament, is synchronously performed with treatment group and observes, and cures 28 examples (accounting for sum 18.7%), and effective 81 examples (account for sum 54%), invalid 32 examples, and total effective rate is 72.7%; Visible, it is effective that Chinese medicine decoction of the present invention is used for treating asthma, and cure rate is high.

Although, above the present invention is described in detail with a general description of the specific embodiments, but on basis of the present invention, it is possible to it is made some modifications or improvements, and this will be apparent to those skilled in the art. Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to the scope of protection of present invention.

Claims

1. the Chinese medicine composition treating asthma, it is characterized in that, described Chinese medicine composition includes the raw material of following weight portion: Herba Medicaginis Lupulinae 10-15 part, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 9-18 part, Herba Leibnitziae 12-18 part, Fructus Terminaliae Billericae 3-10 part, Fructus Paulowniae 13-19 part, Caulis Marsdeniae Tenacissimae 9-15 part, Semen Hyoscyami 5-10 part, orchid root 10-15 part, Vascular aurantii 2-7 part, Cortex Hibisci 6-12 part, Semen Coicis 10-20 part, Folium Ginseng 3-9 part, Pericarpium Trichosanthis 9-12 part, Herba Damnacanthi 6-12 part, Radix Macropanacis Rosthornii 9-15 part, Fructus Psoraleae 6-15 part.

2. the Chinese medicine composition treating asthma as claimed in claim 1, it is characterized in that, described Chinese medicine composition includes the raw material of following weight portion: Herba Medicaginis Lupulinae 12-14 part, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 12-16 part, Herba Leibnitziae 14-16 part, Fructus Terminaliae Billericae 5-7 part, Fructus Paulowniae 15-17 part, Caulis Marsdeniae Tenacissimae 11-13 part, Semen Hyoscyami 7-9 part, orchid root 11-13 part, Vascular aurantii 4-6 part, Cortex Hibisci 8-10 part, Semen Coicis 13-17 part, Folium Ginseng 5-7 part, Pericarpium Trichosanthis 10-11 part, Herba Damnacanthi 8-10 part, Radix Macropanacis Rosthornii 11-13 part, Fructus Psoraleae 8-12 part.

3. the Chinese medicine composition treating asthma as claimed in claim 2, it is characterized in that, described Chinese medicine composition includes the raw material of following weight portion: Herba Medicaginis Lupulinae 13 parts, Ramulus et Folium Cotoneastri Horizontalis (Radix Cotoneastri horizontalis) 14 parts, Herba Leibnitziae 15 parts, Fructus Terminaliae Billericae 6 parts, Fructus Paulowniae 16 parts, Caulis Marsdeniae Tenacissimae 12 parts, Semen Hyoscyami 8 parts, orchid root 12 parts, Vascular aurantii 5 parts, Cortex Hibisci 9 parts, Semen Coicis 15 parts, Folium Ginseng 6 parts, Pericarpium Trichosanthis 10 parts, Herba Damnacanthi 9 parts, Radix Macropanacis Rosthornii 12 parts, Fructus Psoraleae 10 parts.

4. the preparation method of the Chinese medicine composition of the treatment asthma as described in as arbitrary in claim 1-3, it is characterised in that described preparation method is:

5. claim 1-3 arbitrary described Chinese medicine composition application in the medicine of preparation treatment asthma.

6. the Chinese medicine preparation treating asthma, it is characterised in that: described Chinese medicine preparation in the claim 1-3 by effective dose arbitrary described Chinese medicine composition and pharmaceutically acceptable adjuvant form.

7. the Chinese medicine preparation for the treatment of asthma according to claim 6, it is characterised in that: described Chinese medicine preparation is granule, capsule, tablet or pill.