CN105641465A - Traditional Chinese medicine active part composition for controlling oral cavity or throat discomfort caused by haze and preparing method thereof - Google Patents

Traditional Chinese medicine active part composition for controlling oral cavity or throat discomfort caused by haze and preparing method thereof Download PDF

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Publication number
CN105641465A
CN105641465A CN201610041101.2A CN201610041101A CN105641465A CN 105641465 A CN105641465 A CN 105641465A CN 201610041101 A CN201610041101 A CN 201610041101A CN 105641465 A CN105641465 A CN 105641465A
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Prior art keywords
radix
oral cavity
part composition
haze
throat discomfort
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刘敏如
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Female Seven Health Consultation Co Limiteies In Chengdu
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Female Seven Health Consultation Co Limiteies In Chengdu
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Publication of CN105641465A publication Critical patent/CN105641465A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965Asparagus, e.g. garden asparagus or asparagus fern
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967Lilium, e.g. tiger lily or Easter lily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
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  • Microbiology (AREA)
  • Medical Informatics (AREA)
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  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Insects & Arthropods (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine active part composition for controlling oral cavity or throat discomfort caused by haze and a preparing method thereof. The composition is prepared from radix glehniae, radix ophiopogonis, radix asparagi, herba dendrobii, lily, fructus arctii, radix platycodi, periostracum cicada, stiff silkworm, rhizoma polygonati, chrysanthemum flower and licorice root which are mixed according to a certain proportion. The composition can prevent and treat oral cavity or throat discomfort caused by haze and can also treat oral cavity or throat discomfort caused by cold and cough, and has the advantages of being remarkable in treatment effect, free of toxic or side effect and the like. The traditional Chinese medicine active part composition aims at the problem that haze has affected the life and mentality of people seriously and has high application value.

Description

A kind of Chinese medicinal effective-part composition for preventing and treating oral cavity because haze causes or throat discomfort and preparation method thereof
Technical field
The present invention relates to Chinese medicine manufacture field, be specifically related to a kind of Chinese medicinal effective-part composition for preventing and treating oral cavity because haze causes or throat discomfort and preparation method thereof.
Background technology
Haze is due to reasons such as vehicle exhaust, plant gas discharges, makes equivalent aerodynamic diameter continue to build up at 2.5 microns or following fine particle thing (PM2.5) concentration, is subject to the impact of quiet steady weather and the diastrous weather phenomenon that occurs in addition. 2015, the haze of China was extremely serious, and capital haze, Shanghai haze, Guangdong haze etc. bring very big puzzlement to resident living.
PM2.5 itself is a kind of pollutant, is again the carrier of the noxious substance such as heavy metal, polycyclic aromatic hydrocarbon, it is possible to be directly entered and stick in human respiratory tract and alveolar, and then causes the disease such as acute rhinitis, acute bronchitis. For suffering from the patient of bronchus or pulmonary disease, haze weather can make state of an illness acute attack or increase the weight of. It is chronically in haze environment and also can bring out pulmonary carcinoma. Through statistics, even if having exceeded the Beijing-Shanghai wide resident of half to represent to go out and wear mask and even stay at home in haze sky, still there is oral ulcer, have sore throat, the malaise symptoms such as cough, but there is no the flu signs such as watery nasal discharge fever, therefore can conclude that above-mentioned malaise symptoms is that haze causes. At present, except taking various means to control haze, under haze weather, above-mentioned malaise symptoms how is prevented and treated also urgently to be resolved hurrily.
Summary of the invention
Present invention aim at the malaise symptoms such as oral cavity and throat caused according to present haze, it is provided that a kind of therapeutic effect is good and the Chinese medicinal effective-part composition that has no side effect.
The preparation method that another object of the present invention is to provide above-mentioned Chinese medicinal effective-part composition.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
A kind of Chinese medicinal effective-part composition for preventing and treating oral cavity because haze causes or throat discomfort, every part of described Chinese medicinal effective-part composition is made up of following component: Radix Glehniae 10 ~ 40g, Radix Ophiopogonis 2 ~ 20g, Radix Asparagi 5 ~ 18g, Herba Dendrobii 8 ~ 25g, Bulbus Lilii 5 ~ 20g, Fructus Arctii 1 ~ 10g, Radix Platycodonis 2 ~ 15g, Periostracum Cicadae 5 ~ 20g, Bombyx Batryticatus 4 ~ 15g, Rhizoma Polygonati 2 ~ 12g, Flos Chrysanthemi 5 ~ 15g, Radix Glycyrrhizae 1 ~ 8g.
As the further optimal technical scheme of one, every part of described Chinese medicinal effective-part composition is made up of following component: Radix Glehniae 30g, Radix Ophiopogonis 15g, Radix Asparagi 12g, Herba Dendrobii 25g, Bulbus Lilii 15g, Fructus Arctii 5g, Radix Platycodonis 10g, Periostracum Cicadae 12g, Bombyx Batryticatus 8g, Rhizoma Polygonati 5g, Flos Chrysanthemi 10g, Radix Glycyrrhizae 2g.
The preparation method of the Chinese medicinal effective-part composition for preventing and treating oral cavity because haze causes or throat discomfort of the present invention is to be mixed according to proportioning by each crude drug, adds octuple amount water intense fire and boils, then slow fire decocts 20min, to obtain final product.
The instructions of taking of the Chinese medicinal effective-part composition for preventing and treating oral cavity because haze causes or throat discomfort of the present invention is every day three times, takes one week continuously.
Compared with prior art, there is advantages that
(1) Chinese medicinal effective-part composition of the present invention can prevent and treat oral cavity discomfort, throat discomfort or the cough because haze causes;
(2) Chinese medicinal effective-part composition of the present invention can also treat the oral cavity because the reasons such as cold cough cause or throat discomfort;
(3) therapeutic effect of Chinese medicinal effective-part composition of the present invention is good and have no side effect;
(4) raw material of Chinese medicinal effective-part composition of the present invention is easy to get, and preparation method is simple.
Detailed description of the invention
The present invention is explained further below in conjunction with specific embodiment, but the present invention is not limited in any form by embodiment.
Embodiment 1
Preparation portion is for preventing and treating the raw materials used medicine of Chinese medicinal effective-part composition in oral cavity because haze causes or throat discomfort: Radix Glehniae 10g, Radix Ophiopogonis 2g, Radix Asparagi 5g, Herba Dendrobii 8g, Bulbus Lilii 5g, Fructus Arctii 1g, Radix Platycodonis 2g, Periostracum Cicadae 5g, Bombyx Batryticatus 4g, Rhizoma Polygonati 2g, Flos Chrysanthemi 5g, Radix Glycyrrhizae 1g.
Preparation method: after being sufficiently mixed by above-mentioned raw materials medicine, adds octuple amount water intense fire and boils, then slow fire decocts 20min, to obtain final product.
Embodiment 2
Preparation portion is for preventing and treating the raw materials used medicine of Chinese medicinal effective-part composition in oral cavity because haze causes or throat discomfort: Radix Glehniae 40g, Radix Ophiopogonis 20g, Radix Asparagi 18g, Herba Dendrobii 25g, Bulbus Lilii 20g, Fructus Arctii 10g, Radix Platycodonis 15g, Periostracum Cicadae 20g, Bombyx Batryticatus 15g, Rhizoma Polygonati 12g, Flos Chrysanthemi 15g, Radix Glycyrrhizae 8g.
Preparation method: after being sufficiently mixed by above-mentioned raw materials medicine, adds octuple amount water intense fire and boils, then slow fire decocts 20min, to obtain final product.
Embodiment 3
Preparation portion is for preventing and treating the raw materials used medicine of Chinese medicinal effective-part composition in oral cavity because haze causes or throat discomfort: Radix Glehniae 30g, Radix Ophiopogonis 15g, Radix Asparagi 12g, Herba Dendrobii 25g, Bulbus Lilii 15g, Fructus Arctii 5g, Radix Platycodonis 10g, Periostracum Cicadae 12g, Bombyx Batryticatus 8g, Rhizoma Polygonati 5g, Flos Chrysanthemi 10g, Radix Glycyrrhizae 2g.
Preparation method: after being sufficiently mixed by above-mentioned raw materials medicine, adds octuple amount water intense fire and boils, then slow fire decocts 20min, to obtain final product.
Experimental example 1
Choose urbanite totally 1000 people on Beijing, Shanghai, Guangzhou, Tianjin, ground, Shijiazhuang five, when there is burning mouth sensation, oral ulcer, breathing in above-mentioned sample standard deviation throat there is sensation of pricking, the symptom such as throat is itched, cough and got rid of the common disease reasons being easily caused above-mentioned symptom such as flu, stochastic averagina is divided into five groups, A group request for utilization number be 201310164126.8 application for a patent for invention in oral liquid treatment described in embodiment; B group request for utilization number be 201310750580.1 application for a patent for invention in the medicine for preparing of Chinese medicine formula described in embodiment 3 treat; C group request for utilization number be 201410112353.0 application for a patent for invention in effervescent tablet described in embodiment 1 treat;D group request for utilization number be 201510120949.x application for a patent for invention in embodiment 1 gained Fu-brick tea treatment; E group uses the embodiment of the present invention 3 gained medicine decoction to treat. Treatment cycle is 7 days.
Treatment standard is divided into effective, effectively with invalid. The effective transference cure that refers to, checks normal. Effectively refer to that symptom alleviates, check that result has improvement or normal. Invalid refer to that symptom even increases the weight of without being clearly better. Result is as shown in table 1.
Table 1
Effective Effectively Invalid
A group 21 75 104 2 -->
B group 18 77 105
C group 89 90 21
D group 62 88 50
E group 173 27 0
As seen from the results in Table 1, the many symptoms because haze causes can significantly be cured by decoction of the present invention, and evident in efficacy, are better than existing multiple similar medicine.
Experimental example 2
Choosing patient 1000 example of the throat discomfort because Common Cold causes or cough, stochastic averagina is divided into five groups, A group request for utilization number be 201310164126.8 application for a patent for invention in oral liquid treatment described in embodiment; B group request for utilization number be 201310750580.1 application for a patent for invention in the medicine for preparing of Chinese medicine formula described in embodiment 3 treat; C group request for utilization number be 201410112353.0 application for a patent for invention in effervescent tablet described in embodiment 1 treat; D group request for utilization number be 201510120949.x application for a patent for invention in embodiment 1 gained Fu-brick tea treatment; E group uses the embodiment of the present invention 3 gained medicine decoction to treat. Treatment cycle is 7 days.
Treatment standard is divided into effective, effectively with invalid. The effective transference cure that refers to, checks normal. Effectively refer to that symptom alleviates, check that result has improvement or normal. Invalid refer to that symptom even increases the weight of without being clearly better. Result is as shown in table 2.
Table 2
Effective Effectively Invalid
A group 76 50 74
B group 51 62 77
C group 12 13 175
D group 9 28 163
E group 158 36 6
As shown in Table 2, decoction of the present invention can significantly be cured because of the throat discomfort caused and the cough symptom of catching a cold. And find in specifically testing, above-mentioned symptom is in medication i.e. basic disappearance in 3 days.
Experimental example 3
The liver function of experimental subject of checking experiment example 1 and 2, routine blood test, routine urinalysis, stool chemical examination.
Result shows, the indices of experimental subject is all no abnormal, thus, it can be known that its safety of Chinese medicinal effective-part composition described in this patent is good.

Claims (4)

1. the Chinese medicinal effective-part composition being used for preventing and treating oral cavity or throat discomfort because haze causes, it is characterised in that every part of described Chinese medicinal effective-part composition is made up of following component:
Radix Glehniae 10 ~ 40g, Radix Ophiopogonis 2 ~ 20g, Radix Asparagi 5 ~ 18g, Herba Dendrobii 8 ~ 25g, Bulbus Lilii 5 ~ 20g, Fructus Arctii 1 ~ 10g, Radix Platycodonis 2 ~ 15g, Periostracum Cicadae 5 ~ 20g, Bombyx Batryticatus 4 ~ 15g, Rhizoma Polygonati 2 ~ 12g, Flos Chrysanthemi 5 ~ 15g, Radix Glycyrrhizae 1 ~ 8g.
2. it is used for preventing and treating the Chinese medicinal effective-part composition in oral cavity or throat discomfort because haze causes according to claim 1, it is characterised in that every part of described Chinese medicinal effective-part composition is made up of following component:
Radix Glehniae 30g, Radix Ophiopogonis 15g, Radix Asparagi 12g, Herba Dendrobii 25g, Bulbus Lilii 15g, Fructus Arctii 5g, Radix Platycodonis 10g, Periostracum Cicadae 12g, Bombyx Batryticatus 8g, Rhizoma Polygonati 5g, Flos Chrysanthemi 10g, Radix Glycyrrhizae 2g.
3. it is used for the preparation method preventing and treating the Chinese medicinal effective-part composition in oral cavity or throat discomfort because haze causes described in claim 1 or 2, it is characterised in that mixed according to proportioning by each crude drug, add octuple amount water intense fire and boil, then slow fire decocts 20min, to obtain final product.
4. it is used for preventing and treating the instructions of taking of the Chinese medicinal effective-part composition in oral cavity or throat discomfort because haze causes described in claim 1 or 2, it is characterised in that every day three times, take one week continuously.
CN201610041101.2A 2016-01-22 2016-01-22 Traditional Chinese medicine active part composition for controlling oral cavity or throat discomfort caused by haze and preparing method thereof Pending CN105641465A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106421483A (en) * 2016-11-11 2017-02-22 东莞市百替生物科技有限公司 Traditional Chinese medicine composite for treating cough and preparation method
CN107095968A (en) * 2017-04-24 2017-08-29 许昌学院 A kind of anti-haze effervescent tablet of relieving sore-throat clearing lung-heat and preparation method thereof
CN107837355A (en) * 2017-12-19 2018-03-27 北京昆达中医医学研究院 A kind of medicine of the anti-haze of clearing lung-heat
CN108771732A (en) * 2018-08-03 2018-11-09 佛山市泺洲科技有限公司 A kind of moistening lung tonifying spleen Chinese medicine composition

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106421483A (en) * 2016-11-11 2017-02-22 东莞市百替生物科技有限公司 Traditional Chinese medicine composite for treating cough and preparation method
CN107095968A (en) * 2017-04-24 2017-08-29 许昌学院 A kind of anti-haze effervescent tablet of relieving sore-throat clearing lung-heat and preparation method thereof
CN107837355A (en) * 2017-12-19 2018-03-27 北京昆达中医医学研究院 A kind of medicine of the anti-haze of clearing lung-heat
CN108771732A (en) * 2018-08-03 2018-11-09 佛山市泺洲科技有限公司 A kind of moistening lung tonifying spleen Chinese medicine composition

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