CN105596747A - Traditional Chinese medicine preparation for treating spleen kidney qi deficiency type osteoporosis - Google Patents

Traditional Chinese medicine preparation for treating spleen kidney qi deficiency type osteoporosis Download PDF

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CN105596747A
CN105596747A CN201610045954.3A CN201610045954A CN105596747A CN 105596747 A CN105596747 A CN 105596747A CN 201610045954 A CN201610045954 A CN 201610045954A CN 105596747 A CN105596747 A CN 105596747A
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刘建
孙磊
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254Acanthopanax or Eleutherococcus
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    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
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    • A61K36/37Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
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    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
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    • A61K36/884Alismataceae (Water-plantain family)
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Abstract

The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for treating the spleen kidney qi deficiency type osteoporosis. The traditional Chinese medicine preparation is characterized by being prepared from, by weight, 20-30 parts of semen cuscutae, 20-30 parts of curculigo capitulata, 10-15 parts of orchidaceae pecteilis, 10-15 parts of papermulberry fruit, 10-15 parts of euonymus grandiflorus, 15-20 parts of manyprickle acanthopanax roots, 10-15 parts of all-grass of Gynura crepidioides Benth., 15-20 parts of calamus, 10-15 parts of roots of small diuranthera, 10-15 parts of rhizome of Chinese monkshood, 10-15 parts of asarum, 10-15 parts of poria cocos and 10-15 parts of rhizoma alismatis. The traditional Chinese medicine preparation has the advantages that adopted traditional Chinese medicines meet the stipulations of the pharmacopoeia of the People's Republic of China and are safe and reliable; the medicines are compatible and have a function of tonifying spleen and kidney; the traditional Chinese medicine preparation is definite in treatment effect, rapid in effect, high in cure rate, free of side effects and the like when treating the spleen kidney qi deficiency type osteoporosis.

Description

One is treated the osteoporotic Chinese medicine preparation of spleen kidney qi deficiency type
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to one and treat the osteoporotic Chinese medicine preparation of spleen kidney qi deficiency type.
Background technology
Osteoporosis is a kind of general osteopathy, shows as bone total amount and reduces, or the minimizing of unit volume in-seam tissue mass, sclerotin hasMachine composition generates not enough, and the heavy work of secondary calcium salt reduces. The bone amount of normal adult reduces with age growth, therefore the elderly Chang YouPhysiological osteoporosis. Osteoporosis is a kind of performance of aging, if osteoporosis is with fracture, obvious lumbago or nerveSymptom, should be considered as a kind of disease. Can be divided into primary osteoporosis, do not followed other illness that cause osteoporosis volt stateOr disorderly; Secondary osteoporosis, how because incretory dysfunction causes.
The traditional Chinese medical science thinks, this disease many inappropriate by taking good care of native endowment deficiency, the day after tomorrow, prolonged illness is lost and is controlled, old decay, medication is improper drawsSend out. (1) native endowment deficiency, father and mother's body void that has a delicate constitution, a little less than heredity lacks, loses and supports in tire, breeds deficiency, causes kidney qi to loseVoid, kidney essence deficiency, the empty bone of marrow is soft. " Ling Shu Miraculous Pivot or Divine Axis passages through which vital energy circulates " cloud: " it is raw that people is begun, XianCheng's essence, and essence is raw and brains are raw, and bone is for dry,Arteries and veins is battalion, and biceps is firm, and meat is wall, skin is raw and hair long ", illustrate that people all depends in growth, the growth of period from prenatal to postnatal boneKidney essense. (2) eating and drinking without temperance, impairing the spleen and stomach, precise and tinyly not defeatedly eats and drinks immoderately, the reason such as sensual desires partial eclipse, insobriety all can damageTaste. The spleen being the foundation of acquired constitution, source of generating QI and blood, taste are impaired for a long time, and change source is declined few, and internal organs, channels and collaterals, four limbs bones of the body collectively loseIn nourishing, deeply concerned unfavorable, wasting and atrophy of muscle, sends out as this disease. (3) prolonged illness lose control, take good care of the inappropriate the five internal organs that undermine the day after tomorrow, prolonged illness orAfter serious disease, perverse trend is crossed Sheng, visceral-qi damage; Or knot in hemostasis, new blood is not raw; Or lose after being ill in conditioning, healthy tendency virtual loss is difficult multiple,Vital essence loss, injure the five internal organs, " wound of the five internal organs, thoroughly must and kidney ".
According to Chinese medical discrimination theory, this disease can be divided into kidney-essence deficiency and spleen kidney qi deficiency type, and wherein, spleen kidney qi deficiency type syndrome is waistBack of the body extremities joint pain, weakness of limbs, muscle is wither, and light night in daytime is heavy, and textured bone is movable unfavorable, and complexion is shaken white, mouthful light,Spontaneous perspiration, puffiness of the face and limbs, enuresis nocturna increases, deficiency of QI with disinclination to talk, borborygmus stomachache, loose stool or Diarrhoea, the white or neatly of the light fat tender tongue of tongue,Arteries and veins string is heavy unable or thin late.
Summary of the invention
According to above the deficiencies in the prior art, the invention provides one and treat the osteoporotic Chinese medicine preparation of spleen kidney qi deficiency type, its treatmentImitate remarkable, safe and reliable, have no side effect, there is wide potential applicability in clinical practice.
One of the present invention is treated the osteoporotic Chinese medicine preparation of spleen kidney qi deficiency type, it is characterized in that according to parts by weight meter,Be prepared from by following Chinese medicine material: 20~30 parts of the seed of Chinese dodders, 20~30 parts of great Ye thizoma curculiginises, white butterfly are spent 10~15 parts, Paper mulberry Fruit10~15 parts, 10~15 parts of great Hua winged euonymus, 15~20 parts of wilsoniis, exist everywhere 10~15 parts, 15~20 parts of Calamus, small diuranthera root10~15 parts, 10~15 parts of the rhizome of Chinese monkshoods, 10~15 parts of the roots of Chinese wild ginger, 10~15 parts, Poria cocos, 10~15 parts of rhizoma alismatis.
Wherein, preferred version is as follows:
Can, according to parts by weight meter, be prepared from by following Chinese medicine material: 20 parts of the seed of Chinese dodders, 20 parts of great Ye thizoma curculiginises, white butterflySpend 10 parts, 10 parts of Paper mulberry Fruits, 10 parts of great Hua winged euonymus, 15 parts of wilsoniis, exist everywhere 10 parts, 15 parts of Calamus, small diuranthera root10 parts, 10 parts of the rhizome of Chinese monkshoods, 10 parts of the roots of Chinese wild ginger, 10 parts, Poria cocos, 10 parts of rhizoma alismatis.
Also can, according to parts by weight meter, be prepared from by following Chinese medicine material: 30 parts of the seed of Chinese dodders, 30 parts of great Ye thizoma curculiginises, whiteButterfly is spent 15 parts, 15 parts of Paper mulberry Fruits, 15 parts of great Hua winged euonymus, 20 parts of wilsoniis, exist everywhere 15 parts, 20 parts of Calamus, born15 parts of grass, 15 parts of the rhizome of Chinese monkshoods, 15 parts of the roots of Chinese wild ginger, 15 parts, Poria cocos, 15 parts of rhizoma alismatis.
Also can, according to parts by weight meter, be prepared from by following Chinese medicine material: 25 parts of the seed of Chinese dodders, 25 parts of great Ye thizoma curculiginises, whiteButterfly is spent 12 parts, 12 parts of Paper mulberry Fruits, 12 parts of great Hua winged euonymus, 18 parts of wilsoniis, exist everywhere 12 parts, 18 parts of Calamus, born12 parts of grass, 12 parts of the rhizome of Chinese monkshoods, 12 parts of the roots of Chinese wild ginger, 12 parts, Poria cocos, 12 parts of rhizoma alismatis.
A kind of preparation method who treats the osteoporotic Chinese medicine preparation of spleen kidney qi deficiency type of the present invention, in accordance with the following methods preparation:Take Chinese medicine material and join in container according to formula, adding water covers powder and soaks 10~20 minutes, then adds water and do not have powder 3~5Centimetre, decoct with high heat to boiling and use again slow fire boiling instead 20~30 minutes, get filtrate; And then add water and do not have 3~5 lis of powderRice, decocts with high heat to boiling and uses slow fire boiling instead 15~20 minutes again, then removes slag and gets filtrate, and twice filtrate merges.
While taking, each 300ml, one day twice.
Pharmacology analysis:
The seed of Chinese dodder: sweet, temperature. Return liver,kidney,spleen warp. Nourishing liver and kidney, controlling nocturnal emission with astringent drugs contracting urine, antiabortive, improving eyesight, antidiarrheal. For sunImpotence seminal emission, dripping urination, enuresis frequent micturition, soreness and weakness of waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, spleen is suffered from a deficiency of the kidney and is rushed down.
Great Ye thizoma curculiginis: bitter, puckery, flat. Moistening lung for removing phlegm, relieving cough and asthma, calm invigorating the spleen, invigorates the kidney and stops nocturnal emission. For dyspnea and cough due to deficiency of the kidney,Soreness of waist and knee joint, leukorrhea, seminal emission.
White butterfly flower: sweet, tepor. Tonifying kidney and strengthening yang, invigorating the spleen. Cure mainly lumbago due to the kidney deficiency, chronic nephritis, orchitis, weakness of the spleen and the stomach.
Paper mulberry Fruit: sweet, cold. Return liver, kidney channel. Kidney tonifying clearing liver, improving eyesight, diuresis. For soreness and weakness of waist and knees, consumptive disease hectic fever due to yin, headDizzy blurred vision, the raw screen film of order, oedema turgor.
Great Hua winged euonymus: micro-hardship, puckery, flat. Wines used as antirheumatic, relaxing muscles and tendons network, kidney tonifying. Control dysentery from the beginning of, stomachache, lumbago due to the kidney deficiency, windWet pain, hemostasis amenorrhoea.
Wilsonii: pungent, micro-hardship, temperature. Return spleen, kidney, the heart channel of Hang-Shaoyin. Replenish qi to invigorate the spleen, tonify the kidney to relieve mental strain. For the insufficiency of both the spleen and the kindey, body voidWeak, poor appetite, soreness of waist and knee joint, insomnia and dreamful sleep.
Exist everywhere: bitter, micro-pungent, flat. Spleen strengthening and bloatedness reducing. For indigestion, insufficiency of the spleen edema.
Calamus: toil, temperature. Reduce phlegm, have one's ideas straightened out, invigorating the spleen, dampness removing. Control epilepsy, palpitate with fear forgetful, mind is not asked, and humidity hysteresis ruffian is swollen,Dysentery, rheumatalgia pain, the carbuncle scabies that swells.
Small diuranthera root: light, flat. Clearing heat and detoxicating, strong swollen dampness removing. Control rheumatism, infantile malnutrition, mastitis, venomous snake bite.
The rhizome of Chinese monkshood: pungent, heat, poisonous. Dispellieg cold and dampness, loose ailment said due to cold or exposure, Wen Jing, pain relieving, controls wind-cold-dampness arthralgia, severe and wadering arthralgia pain, four limbs are arrestedContraction, hemiplegia, a wind headache, trusted subordinate's crymodynia, cloudy subcutaneous ulcer pyogenic infections.
The root of Chinese wild ginger: pungent, temperature. The thoughts of returning home, lung, kidney channel. Expelling wind and clearing away cold, understand things pain-stopping, warming lung to reduce watery phlegm. For anemofrigid cold, headBitterly, toothache, nasal obstruction nasosinusitis, arthralgia due to wind-dampness, phlegm and retained fluid is breathed with cough.
Poria cocos: sweet, light, flat. The thoughts of returning home, lung, spleen, kidney channel. Clearing damp and promoting diuresis, the peaceful heart of invigorating the spleen. For oedema oliguria, phlegm and retained fluidDizzyly throb with fear, insufficiency of the spleen food is few, and have loose bowels in loose stool, confused and worried, palpitation with fear insomnia.
Rhizoma alismatis: sweet, cold. Return kidney, urinary bladder channel. Diuresis, clearing away damp-heat. For difficult urination, oedema turgor, the oliguria of having loose bowels,Phlegmatic vertigo, heat is drenched puckery pain; High fat of blood.
In medicament composing prescription of the present invention, the seed of Chinese dodder, great Ye thizoma curculiginis, Bai Diehua, Paper mulberry Fruit, great Hua winged euonymus kidney-tonifying sperm-generating; Wilsonii,Exist everywhere, Calamus, small diuranthera root strengthening the spleen and replenishing qi; It is inflexible anxious that the rhizome of Chinese monkshood, the root of Chinese wild ginger are alleviated stomachache; Poria cocos, rhizoma alismatis are alleviated edema arthroncus.
The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable. All medicine phasesWith there is the effects such as invigorating spleen and kidney, treatment spleen kidney qi deficiency type osteoporosis have determined curative effect, instant effect, cure rate high, without secondaryThe features such as effect.
Curative effect judgement:
1, inclusion criteria
Choose spleen kidney qi deficiency type sufferers of osteoporosis face 100 examples, wherein, the male sex's 52 examples, women's 48 examples, 68 years old mean age.
2, methods for the treatment of
Take Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 300ml, 15 days courses for the treatment of.
3, evaluation of clinical curative effect standard
Osteoporosis bone density efficacy determination, Western medicine diagnose standard: Chinese's osteoporosis suggestion diagnostic criteria (the second original text)" new Chinese medicine guideline of clinical investigations ", the traditional Chinese medical science is according to " new Chinese medicine guideline of clinical investigations " (trial version in 2002)The guideline of clinical investigations of osteoporosis " new Chinese medicine treatment " as evaluation criterion;
First calculate bone density changing value=(the front bone density of bone density-treatment after treatment)/bone density × 100% before treating;
Effective: bone density rate of change is more than or equal to the minimum marked change value of bone density;
Effective: bone density rate of change is between the minimum marked change value of positive and negative bone density;
Invalid: bone density rate of change is less than the minimum marked change value of negative bone density.
The wherein minimum marked change of bone density value=2.77 × (%CV), the CV-coefficient of variation;
Total effective rate=(effective+effectively)/total case load × 100%.
4, result
Effective 42 examples, effective 56 examples, invalid 2 examples, total effective rate is 98%.
Below enumerate a model case:
(1) Zhang, female, 58 years old. Patient's waist has a pain in the leg the several years, recently increases the weight of, and be osteoporosis through hospital diagnosis, rear clothesMore than the bimester of with western medicine, do not feel any better, rear employing Chinese traditional treatment, according to dialectical, patient back extremities joint pain, four limbsUnable, complexion is shaken white, mouthful light, spontaneous perspiration, and puffiness of the face and limbs, deficiency of QI with disinclination to talk, tongue fur is white, and arteries and veins string is heavy unable, belongs to spleen kidney qi deficiencyType osteoporosis. Take the present invention and treat osteoporotic Chinese medicine preparation, take medicine after two courses for the treatment of, low-back pain symptom is obviousAlleviate, continue a course for the treatment of of medication treatment after pain symptom substantially disappear, body movement power obviously strengthens, check bone density beforeTake an evident turn for the better, above symptom fades away.
Detailed description of the invention
The present invention will be further described by the following examples.
Embodiment 1:
One is treated the osteoporotic Chinese medicine preparation of spleen kidney qi deficiency type, according to parts by weight meter, is prepared from by following Chinese medicine material:20 parts of the seed of Chinese dodders, 20 parts of great Ye thizoma curculiginises, white butterfly spend 10 parts, 10 parts of Paper mulberry Fruits, 10 parts of great Hua winged euonymus, 15 parts of wilsoniis,Exist everywhere 10 parts, 15 parts of Calamus, 10 parts of small diuranthera roots, 10 parts of the rhizome of Chinese monkshoods, 10 parts of the roots of Chinese wild ginger, 10 parts, Poria cocos, 10 parts of rhizoma alismatis.
Embodiment 2:
One is treated the osteoporotic Chinese medicine preparation of spleen kidney qi deficiency type, according to parts by weight meter, is prepared from by following Chinese medicine material:30 parts of the seed of Chinese dodders, 30 parts of great Ye thizoma curculiginises, white butterfly spend 15 parts, 15 parts of Paper mulberry Fruits, 15 parts of great Hua winged euonymus, 20 parts of wilsoniis,Exist everywhere 15 parts, 20 parts of Calamus, 15 parts of small diuranthera roots, 15 parts of the rhizome of Chinese monkshoods, 15 parts of the roots of Chinese wild ginger, 15 parts, Poria cocos, 15 parts of rhizoma alismatis.
Embodiment 3:
One is treated the osteoporotic Chinese medicine preparation of spleen kidney qi deficiency type, according to parts by weight meter, is prepared from by following Chinese medicine material:25 parts of the seed of Chinese dodders, 25 parts of great Ye thizoma curculiginises, white butterfly spend 12 parts, 12 parts of Paper mulberry Fruits, 12 parts of great Hua winged euonymus, 18 parts of wilsoniis,Exist everywhere 12 parts, 18 parts of Calamus, 12 parts of small diuranthera roots, 12 parts of the rhizome of Chinese monkshoods, 12 parts of the roots of Chinese wild ginger, 12 parts, Poria cocos, 12 parts of rhizoma alismatis.
Embodiment 4:
Embodiment 1~3 is prepared in accordance with the following methods: take Chinese medicine material and join in container according to formula, adding water and cover powderSoak 20 minutes, then add water and do not have 5 centimetres of powder, decoct with high heat to boiling and use again slow fire boiling instead 30 minutes, get filtrate;And then add water and do not have 5 centimetres of powder, decoct with high heat to boiling and use again slow fire boiling instead 20 minutes, then remove slag and get filtrate,Twice filtrate merges.
While taking, each 300ml, one day twice.

Claims (4)

1. the osteoporotic Chinese medicine preparation for the treatment of spleen kidney qi deficiency type, is characterized in that according to parts by weight meter, by following Chinese medicineRaw material is prepared from: 20~30 parts of the seed of Chinese dodders, 20~30 parts of great Ye thizoma curculiginises, white butterfly spend 10~15 parts, 10~15 parts of Paper mulberry Fruits,10~15 parts of great Hua winged euonymus, 15~20 parts of wilsoniis, exist everywhere 10~15 parts, 15~20 parts of Calamus, 10~15 parts of small diuranthera roots,10~15 parts of the rhizome of Chinese monkshoods, 10~15 parts of the roots of Chinese wild ginger, 10~15 parts, Poria cocos, 10~15 parts of rhizoma alismatis.
2. one according to claim 1 is treated the osteoporotic Chinese medicine preparation of spleen kidney qi deficiency type, it is characterized in that according to heavyAmount umber meter, is prepared from by following Chinese medicine material: 20 parts of the seed of Chinese dodders, 20 parts of great Ye thizoma curculiginises, white butterfly are spent 10 parts, Paper mulberry Fruit10 parts, 10 parts of great Hua winged euonymus, 15 parts of wilsoniis, exist everywhere 10 parts, 15 parts of Calamus, 10 parts of small diuranthera roots, 10 parts of the rhizome of Chinese monkshoods,10 parts of the roots of Chinese wild ginger, 10 parts, Poria cocos, 10 parts of rhizoma alismatis.
3. one according to claim 1 is treated the osteoporotic Chinese medicine preparation of spleen kidney qi deficiency type, it is characterized in that according to heavyAmount umber meter, is prepared from by following Chinese medicine material: 30 parts of the seed of Chinese dodders, 30 parts of great Ye thizoma curculiginises, white butterfly are spent 15 parts, Paper mulberry Fruit15 parts, 15 parts of great Hua winged euonymus, 20 parts of wilsoniis, exist everywhere 15 parts, 20 parts of Calamus, 15 parts of small diuranthera roots, 15 parts of the rhizome of Chinese monkshoods,15 parts of the roots of Chinese wild ginger, 15 parts, Poria cocos, 15 parts of rhizoma alismatis.
4. one according to claim 1 is treated the osteoporotic Chinese medicine preparation of spleen kidney qi deficiency type, it is characterized in that according to heavyAmount umber meter, is prepared from by following Chinese medicine material: 25 parts of the seed of Chinese dodders, 25 parts of great Ye thizoma curculiginises, white butterfly are spent 12 parts, Paper mulberry Fruit12 parts, 12 parts of great Hua winged euonymus, 18 parts of wilsoniis, exist everywhere 12 parts, 18 parts of Calamus, 12 parts of small diuranthera roots, 12 parts of the rhizome of Chinese monkshoods,12 parts of the roots of Chinese wild ginger, 12 parts, Poria cocos, 12 parts of rhizoma alismatis.
CN201610045954.3A 2016-01-16 2016-01-16 Traditional Chinese medicine preparation for treating spleen kidney qi deficiency type osteoporosis Pending CN105596747A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105816686A (en) * 2016-06-01 2016-08-03 朱朝晖 Traditional Chinese medicine preparation for treating osteoporosis

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* Cited by examiner, † Cited by third party
Title
满江等: "《本草纲目中的老人健康养生经》", 31 January 2013, 上海科学技术文献出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105816686A (en) * 2016-06-01 2016-08-03 朱朝晖 Traditional Chinese medicine preparation for treating osteoporosis

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