CN105582320A - Traditional Chinese medicine preparation for treating otitis media and preparation method - Google Patents
Traditional Chinese medicine preparation for treating otitis media and preparation method Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a traditional Chinese medicine preparation for treating otitis media and a preparation method, and belongs to the field of traditional Chinese medicine. Raw materials for preparing the effective ingredients of the traditional Chinese medicine preparation comprise pothos chinensis, vitis bryoniifolia, herb of macleaya cordata, cottonrose hibiscus leaves, pomegranate flowers, stems and leaves of garden lettuces, herb of galium aparine, waxplant stems or leaves, rhizoma calami, herb of menyanthes trifoliate, seeds of abutilon theophrasti, fruit of rhodomyrtus tomentosa, armillaria tabescens, herb of clavateleaf oberonia, rhizoma curculiginis and herb of filifolium sibiricum (L.)Kitam.. The traditional Chinese medicine preparation is appropriate in compatibility of the selected medicinal materials, conforms to the theory of the traditional Chinese medicine and pharmacy and the modern medicine and pharmacology, has the effects of diminishing swelling, expelling pus, dispelling wind, removing toxicity, eliminating dampness and relieving itching, has the significant treatment effect on treating the otitis media and is convenient to take, short in treatment course, capable of rapidly achieving the effects, safe and free of toxic and side effects, and the otitis media does not relapse after being cured; the purpose of treating both symptoms and root causes can be achieved, people can normally work and live in the period of taking the preparation, the miraculous effect and practicability are achieved, and traditional Chinese medicine preparation and the preparation method are worthy of wide application and popularization in clinic.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation and preparation method who treats tympanitis.
Background technology
Tympanitis is to involve the inflammatory disease that middle ear comprise Eustachian tube, tympanum, tympanic antrum and all or part of structure of mastoid air cellBecome, be apt to occur in children. Can be divided into apyetous and suppurative two large classes. Apyetous person comprises that secretory otitis media, air pressure damageWound property tympanitis etc., suppurative person has acute and chronic dividing. Specificity inflammation is shown in very little, as tuberculous otitis media etc.
Otitis media acuta is the acute suppurative inflammation of middle-ear mucosa, is infected by Eustachian tube approach. Pharyngeal, nose after fluInflammation spread to Eustachian tube, there is congested, swelling in pharyngeal opening of auditory tube and tube chamber mucous membrane, ciliary movement generation obstacle, in causingOtitis. Common pathogenic bacteria are mainly pneumococcus, haemophilus influenzae etc.; In nasal mucus, contain a large amount of virus and bacterium, asFruit nostril, both sides all pinches firmly and blows, and pressure forces nasal mucus to be extruded to choana, arrives Eustachian tube, causes tympanitis; SwimmingIn time, should avoid water to swallow in entrance, causes tympanitis in order to avoid water enters middle ear by pharynx nasalis. The tympanic membrane perforation due to wound,Forbid dripping any water sample liquid, in order to avoid affect the healing of wound. Available sterilized cotton ball stops up external auditory meatus, in order to avoid infection-induced middle earScorching; If infant's dorsal position is sucked the breast, because child's Eustachian tube is more straight, and tube chamber is shorter, and internal diameter is wider, and milk can be throughEustachian tube is choked and is caused tympanitis into middle ear; Smoking comprises passive smoking, also can cause tympanitis. Smoking can cause the moving of generalArteries and veins sclerosis, especially the nicotine in cigarette enters blood, makes small blood vessel spasm, and blood viscosity increases, to inner ear supply bloodArteriole harden, cause inner ear blood supply insufficiency, have a strong impact on hearing; Listen for a long time the large decibel of rock and roll class with earphoneMusic, if the time is longer, also easily causes chronic otitis media.
If tympanitis treatment not in time, not thorough, mostly may transfer chronic otitis media to, in addition, if having chronicRhinitis, chronic nasosinusitis and chronic tonsillitis exist, and bacterium may be invaded tympanum repeatedly, and tympanitis hides to get off to causeChronic otitis media. Facial paralysis, facial nerve is very near apart from tympanum, if damage it, will cause facial paralysis. Labyrinthitis, if inflammationInwardly invade, enter inner ear and can cause labyrinthitis, cause dizzy and nauseating, vomiting etc. Intracranial complication comprises meningitis, brainThe outer abscess of film and brain abscess. No matter there is any situation, all can be in peril of one's life. Various abscess, as retroauricular subperiosteal abscess,Under temporalis, abscess, external auditory meatus rear wall abscess etc., occur after abscess, can touch very soft enclosed mass in part, red and swollen, sharp ache,And there is a high fever. If processed not in time, abscess spreads to neck, causes pain when neck rotates, and has destruction neck when seriousTrunk, causes death.
At present, be main to treatment tympanitis mainly with integrative therapy, western medical treatment adopts anti-inflammatory drug more, takes stopgap measures and does not controlThis, curative effect is low, and side effect is large, and drug withdrawal is easily recurrence, and Chinese traditional treatment short treating period, instant effect have no side effect, easily by patientAccept.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method who treats tympanitis; The selected medicinal material of Chinese medicine preparation of the present inventionCompatibility is suitable, meets traditional Chinese medicine and pharmacy and modern medicine theory, and there is detumescence and apocenosis, the removing toxic substances of dispeling the wind, the antipruritic effect of eliminating dampness,Treatment tympanitis is had to significant curative effect, taking convenience, short treating period, instant effect, non-relapse after healing, safety non-toxic is secondary to be doneWith, can reach the object for the treatment of both principal and secondary aspect of disease, period in a medicine can normally be worked and live, and special effect practicality, extensively pushes away on clinicWide application.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for tympanitis, make raw material composition and the parts by weight of described Chinese medicine preparation active ingredientFor:
Raw material composition and the parts by weight of making described Chinese medicine preparation active ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation active ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation active ingredient are:
Treat a preparation method for the Chinese medicine preparation of tympanitis, comprise following processing step:
(1) Chinese pothos herb, cottonrose hibiscus leaf, pomegranate flower, lettuce, piemarker, rock green onion and rabbit hair wormwood artemisia are cleaned, put into container, add 8The distilled water of～10 times of amounts, soaked after 5～6 hours, boiled 3～4 hours, extracted; Again add 6～8 times of amount distilled water, boil2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heating is boiled 1～2 hour, extracts; Merge No. three times extract, mistakeFilter, obtains filtrate, is condensed into the thick paste that at 60 DEG C, relative density is 1.10～1.13, for subsequent use;
(2) clean Ying Azulene, catchweed bedstraw herb, ball orchid and buckbean, and chopping, puts into container, strand juice, and filter impurity, stays juice standbyWith;
(3) macleaya cordata, rhizoma calami and Armilariella tabescens are put into container, carry out pulverization process, grind into powder, cross 160 order fine powders, standbyWith;
(4) mountain Shen is cleaned, immerse 80% the alcohol solution dipping 1～2 hour of 3 times of amounts, heating is extracted 3 hours,Reclaim ethanol, filter, obtain filtrate, the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16, for subsequent use;
(5) thizoma curculiginis is cleaned, is mixed thoroughly with yellow rice wine, run through rear slow fire and fry to micro-dry, take out and dry in the air to absolutely dry, be placed in mortar,Grind into powder, cross 200 order fine powders.
(6) above-mentioned steps (1)～(5) prepared thick paste, juice and fine powder are mixed, make capsule, described in obtainingThe Chinese medicine preparation for the treatment of tympanitis.
The property of medicine of the present invention's Chinese medicine used is as follows:
Chinese pothos herb: lightly seasoned, property is flat. Dispel rheumatism, promoting blood circulation to remove blood stasis, food dispersing cough suppressing. For traumatic injury, advanced schistosomiasisHepatosplenomegaly, rheumatic arthritis, infantile malnutrition, cough, fracture is controlled in external application, tympanitis, nasosinusitis. " Guangxi Chinese medicinal herbal " carries:" heat-clearing, removing toxic substances, wines used as antirheumatic. Control treating rheumatic ostealgia, ear sore. "
Ying Azulene: taste acid, sweet, puckery, property is flat; Return liver, stomach warp. Clearing heat and detoxicating, dispel rheumatism. For hepatitis, appendicitis, mammary glandInflammation, lung abscess, multiple abscess, rheumatic arthritis; Sore swollen toxin is controlled in external application, tympanitis, snake bite and insect sting. " Fujian Chinese herbal medicine "Carry: " cooling blood and hemostasis, subdhing swelling and detoxicating. "
Macleaya cordata: bitter, cold in nature, very toxic. The removing toxic substances of dispeling the wind, eliminating stasis to subdue swelling. For traumatic injury, rheumatic arthritis, carbuncleFuruncle poison, the ulcer of lower limb, felon, abscess, acute tonsillitis, tympanitis, trichomonas vaginitis, scalds stubborn dermatitis. " the Jiangxi peopleBetween herbal medicine " carry: " and control ulcer on the shank, stubborn dermatitis, white baldhead, soaks in vinegar seven, eight with leaf, the rotten deposited affected part of pestle, changes for one day one. " modern medicineStudies confirm that, three kinds of alkaloids in macleaya cordata, have nematocidal effect, and some bacterium and fungi are also had to inhibition effect.
Cottonrose hibiscus leaf: taste is pungent, bitter, cool in nature; Return lung, Liver Channel. Qingfei Liangxue, detumescence and apocenosis. For cough with lung heat, plumpness noseInflammation, lymphnoditis, appendicitis, carbuncle furuncle abscess, otitis media acuta, burn, scald.
Pomegranate flower: taste acid, puckery, property is flat. Cool blood, hemostasis. Main bleeding from five sense organs or subcutaneous tissue, spits blood, traumatism and bleeding, and irregular menstruation, redly collapses leukorrhea,Tympanitis. " wild medicine is planted figure and said " carries: " control middle ear inflammation, prevent from suppurating. "
Lettuce: bitter, sweet, cool in nature; Return stomach, small intestinl channel; Diuresis, logical breast is clearing heat and detoxicating. Cure mainly difficult urination, hematuria, breastJuice is obstructed, worm snake bite, and pyogenic infections, helps digestion. " daily book on Chinese herbal medicine " carries: " sharp the five internal organs, mend muscles and bones, open diaphragm heat, qualcomm meridian, removing foul breath is whiteTeeth, bright eyes. "
Catchweed bedstraw herb: pungent, the micro-hardship of taste, cold nature; Return Shao Yin, Taiyin channels. Clearing away damp-heat, the loose stasis of blood, detumescence, removing toxic substances. Control stranguria with turbid discharge, urineBlood, traumatic injury, acute appendicitis, furuncle, tympanitis. " the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control damp and hot, all through visitor's heat, consumptive disease, virgin consumptive disease, muscles and bones painBitterly, heat is drenched, red white turbid urine, beautiful stem pain. Move back blood system dysphoria with smothery sensation, only hematuria. "
Ball orchid: bitter, cold in nature, mild toxicity; Return lung, the heart, Liver Channel. Clearing heat and detoxicating, expelling wind and removing dampness. For popular B-mode brainInflammation, pneumonia, bronchitis, orchitis, rheumatic arthritis, difficult urination; The swollen furunculosis of carbuncle is controlled in external application. " Fujian traditional herbal medicine "Carry: " wines used as antirheumatic, removing heat from the liver, subduing inflammation. "
Rhizoma calami: taste is pungent, bitter, warm in nature; The thoughts of returning home, liver, stomach warp; Dissipating phlegm for resuscitation, dehumidifying stomach invigorating, killing parasites to relieve itshing. Main coma due to blocking of the respiratory system duskFan, apoplexy, epilepsy, palpitates with fear forgetful, Hiccough and deaf, dyspeptic abdominalgia, dysentery is had loose bowels, rheumatalgia pain, eczema, scabies.
Buckbean: sweet, the micro-hardship of taste, cold in nature; The thoughts of returning home, the spleen channel. Reducing fever and causing diuresis, stomach invigorating, calms the nerves. For gastritis, indigestion, courageCapsulitis, jaundice, hypertension, palpitaition, insomnia. " the conventional Chinese herbal medicine handbook in the north " carries: " reinforcing spleen to promote digestion, mental-tranquilization. Control gastritis,Stomachache, indigestion, palpitation and insomnia, confused and worried. "
Piemarker: bitter, property is flat, returns spleen, stomach warp; Clearing heat and promoting diuresis, removing toxic substances is had one's ideas straightened out. Cure mainly dysentery, tympanitis, tinnitus, deafness,Orchitis, suppurative tonsillitis, swollen ulcer drug. " Chinese herbal medicine is commonly used in Shanghai " carries: " herb: removing toxic substances, dispel the wind. Control dysentery, middle earInflammation, tinnitus, deafness, joint pain. "
Mountain Shen: taste is sweet, puckery, property is flat. Nourish blood, hemostasis, puckery intestines, controlling nocturnal emission with astringent drugs. Cure mainly the deficiency of blood, spit blood, nosebleed epistaxis, has blood in stool, dysentery,Prolapse of the anus, tinnitus, seminal emission, metrorrhagia, under band. " detailed outline is picked up any lost article from the road " carries: " nourish blood, improving eyesight. "
Armilariella tabescens: bitter, cold in nature; Return liver, gallbladder channel. Clearing heat and detoxicating. Main acute and chronic cholecystitis, infection of biliary tract, hepatitis, appendixInflammation, tympanitis.
Rock green onion: pungent, the micro-hardship of taste, cool in nature; Return kidney, urinary bladder channel. Clearing heat and detoxicating, loose stasis of blood hemostasis. Main bronchus inflammation, pneumonia, liverInflammation, urinary tract infections, tympanitis, sore carbuncle, fracture, traumatism and bleeding.
Thizoma curculiginis: taste is pungent, hot in nature, poisonous, return kidney,liver,spleen warp. Kidney-replenishing, strengthening the bones and muscles, dispellieg cold and dampness. For impotence cold sperm, muscleThe atrophic debility of bones is soft, the cold numbness of waist knee, and the deficiency of yang is cold rushes down. " Haiyao Bencao, Oversea Materia Medica " carries: " main air, mends warm waist pin, clear five viscera settling, and strengthening the bones and muscles, helps digestion. A surnameAnd multiple benefit, main husband's seven kinds of impairments, improve visual and auditory acuity, beneficial biceps, fills out marrow, Yiyang. "
Rabbit hair wormwood artemisia: bitter, cold in nature. Clearing heat and detoxicating, anti-inflammation, calms the nerves relieving convulsion, regulating menstruation, hemostasis. Cure mainly the high heat of infectious disease,Take orally heartbeat, insomnia, neurasthenia effect are being shown, to menorrhalgia, irregular menstruation also has certain curative effect. Swollen carbuncle is controlled in external application,Ulcer on the shank, tympanitis and other surgery pyogenic infection disease.
The present invention compared with prior art, has following beneficial effect:
1, the selected medicinal material compatibility of Chinese medicine preparation of the present invention is suitable, meets traditional Chinese medicine and pharmacy and modern medicine theory, and hasDetumescence and apocenosis, the removing toxic substances of dispeling the wind, the antipruritic effect of eliminating dampness, have significant curative effect, taking convenience to treatment tympanitis.
2, Chinese medicine preparation short treating period of the present invention, instant effect, non-relapse after healing, safe without toxic side effect, can reach markThis double object of controlling, period in a medicine can normally be worked and live, special effect practicality, wide popularization and application on clinic.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of Chinese medicine preparation active ingredient of the present invention are:
Treat a preparation method for the Chinese medicine preparation of tympanitis, comprise following processing step:
(1) Chinese pothos herb, cottonrose hibiscus leaf, pomegranate flower, lettuce, piemarker, rock green onion and rabbit hair wormwood artemisia are cleaned, put into container, add 8The distilled water of～10 times of amounts, soaked after 5～6 hours, boiled 3～4 hours, extracted; Again add 6～8 times of amount distilled water, boil2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heating is boiled 1～2 hour, extracts; Merge No. three times extract, mistakeFilter, obtains filtrate, is condensed into the thick paste that at 60 DEG C, relative density is 1.10～1.13, for subsequent use;
(2) clean Ying Azulene, catchweed bedstraw herb, ball orchid and buckbean, and chopping, puts into container, strand juice, and filter impurity, stays juice standbyWith;
(3) macleaya cordata, rhizoma calami and Armilariella tabescens are put into container, carry out pulverization process, grind into powder, cross 160 order fine powders, standbyWith;
(4) mountain Shen is cleaned, immerse 80% the alcohol solution dipping 1～2 hour of 3 times of amounts, heating is extracted 3 hours,Reclaim ethanol, filter, obtain filtrate, the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16, for subsequent use;
(5) thizoma curculiginis is cleaned, is mixed thoroughly with yellow rice wine, run through rear slow fire and fry to micro-dry, take out and dry in the air to absolutely dry, be placed in mortar,Grind into powder, cross 200 order fine powders.
(6) above-mentioned steps (1)～(5) prepared thick paste, juice and fine powder are mixed, make capsule, described in obtainingThe Chinese medicine preparation for the treatment of tympanitis.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal;Within 7 days, be 1 course for the treatment of, can fully recover 2～4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
Raw material composition and the weight of Chinese medicine preparation active ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of Chinese medicine preparation active ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of Chinese medicine preparation active ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
Raw material composition and the weight of Chinese medicine preparation active ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of tympanitis, the routine clinical observation of tympanitis patient 150 that selection is made a definite diagnosis, patient divides at randomBecome two groups for the treatment of group and control groups, treatment group 75 examples, the wherein male sex's 37 examples, women's 38 examples, 8～39 years old age, mean age23.5 years old, average course of disease 1 year; Control group 75 examples, the wherein male sex's 38 examples, women's 37 examples, 7～40 years old age, mean age 23.5Year, average course of disease 1 year.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of control group are basically identical, without significant difference, have comparableProperty.
2, medicament selection:
Treatment group is taken Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every0.5g), warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, can fully recover 2～4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice to drink and addsAmount.
Control group uses ofloxacin ear drops, drips ear, be grown up one time 6～10,2～3 times on the one, after droplet ear, carry out approximatelyWithin 10 minutes, ear is bathed, and according to a suitably increase and decrease ear number of times of symptom, children's is dripped to number and cut down according to the circumstance.
3, efficacy determination:
(1) cure: cardinal symptom all disappears, and auditory rehabilitation is normal.
(2) effective: cardinal symptom obviously alleviates, hearing is recovered to some extent.
(3) effective: cardinal symptom alleviates to some extent, and hearing is obviously recovered.
(4) invalid: by treating rear cardinal symptom without alleviating or increasing the weight of.
4, result:
Select in the treatment group of Chinese medicine preparation of the present invention, cure 38 examples, effective 22 examples, effective 13 examples, invalid 2 examples, cureRate 50.7%, total effective rate 97.3%.
In control group, cure 31 examples, effective 18 examples, effective 12 examples, invalid 14 examples, cure rate 41.3%, total effective rate81.3％。
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than control group.
Model case is given an example:
1, desolate certain, man, 9 years old, people from Wuqing District, Tianjin. Patient suffers from tympanitis ear flows out sticky water, through taking Chinese medicine of the present inventionPreparation for treating, took after 1 course for the treatment of, and symptom is alleviated to some extent, continued to take after 1 course for the treatment of transference cure, recovery from illness.
2, journey, female, 19 years old, people from Jinzhou, Liaoning. Patient suffers from tympanitis ear flows out purulence mucus, uses several drugs to controlTreat, have no improvement, introduce the treatment of Lai Wo institute through friend, through taking Chinese medicine preparation treatment of the present invention, take after 1 course for the treatment of symptomTake a turn for the better to some extent, take after 2 courses for the treatment of, symptom all disappears, and recovery from illness is followed up a case by regular visits to so far without recurrence.
3, Zeng, man, 25 years old, people from Banan District, Chongqing. Patient suffers from otitis media suppurative 2 months, uses medicine treatment, noGet better and turn, take upon somebody's introduction Chinese medicine preparation treatment of the present invention, take after 1 course for the treatment of, symptom alleviates to some extent, takes 3 courses for the treatment ofAfter, transference cure, recovery from illness, follows up a case by regular visits to after 1 year without recurrence.
4, Lu, female, 20 years old, people from Binzhou, Shandong. Patient, before 6 months, occurs that without obvious inducement right ear canal suppurates, and purulence isYellow-white, without the trace of blood, patient's private prosecution companion cephalagia, gradually occur revolving dizzy, tinnitus, poor appetite, through taking Chinese medicine of the present inventionPreparation for treating, took after 1 course for the treatment of, and symptom takes a turn for the better to some extent, continued to take after 3 courses for the treatment of, and symptom all disappears, recovery from illness.
5, Lu, man, 34 years old, people from Taizhou, Jiangsu. Patient suffers from nonsuppurative otitis media 2 years, uses multi-medicament treatment, controlsTherapeutic effect is not good, through taking Chinese medicine preparation treatment of the present invention, takes after 2 courses for the treatment of, and symptom alleviates to some extent, take after 4 courses for the treatment of,Transference cure, recovery from illness, follows up a case by regular visits to after half a year without recurrence.
6, Yuan, female, 15 years old, Taizhou of Zhejiang people. Patient is whenever flu auris dextra feels suffocation sense, slight headache, Western medicine diagnoseFor tympanitis, after injection for curing a period of time, result for the treatment of ideal, introduces through friend, takes Chinese medicine preparation treatment of the present invention, clothesWith after 1 course for the treatment of, symptom is alleviated to some extent, continues to take after 2 courses for the treatment of, and symptom all disappears, recovery from illness.
7, journey, man, 27 years old, Heze City, Shandong Province people. Patient suffers from otitis media suppurative 3 months, uses several drugs treatment,Lose improvement, through taking Chinese medicine preparation treatment of the present invention, take after 1 course for the treatment of, symptom alleviates to some extent, takes after 3 courses for the treatment of diseaseShape disappears, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
Claims (5)
1. a Chinese medicine preparation for the treatment of tympanitis, is characterized in that: the raw material composition of making described Chinese medicine preparation active ingredientAnd parts by weight are:
2. a kind of Chinese medicine preparation for the treatment of tympanitis according to claim 1, is characterized in that: make described Chinese medicine preparationRaw material composition and the parts by weight of active ingredient are:
3. a kind of Chinese medicine preparation for the treatment of tympanitis according to claim 1, is characterized in that: make described Chinese medicine preparationRaw material composition and the parts by weight of active ingredient are:
4. a kind of Chinese medicine preparation for the treatment of tympanitis according to claim 1, is characterized in that: make described Chinese medicine preparationRaw material composition and the parts by weight of active ingredient are:
5. a preparation method who treats the Chinese medicine preparation of tympanitis as described in claim 1～4 any one, is characterized in that:Comprise following processing step:
(1) Chinese pothos herb, cottonrose hibiscus leaf, pomegranate flower, lettuce, piemarker, rock green onion and rabbit hair wormwood artemisia are cleaned, put into container, add 8～10Doubly the distilled water of amount, soaked after 5～6 hours, boiled 3～4 hours, extracted; Again add 6～8 times of amount distilled water, boil 2～3Hour, extract; Finally, add 4～6 times of amount distilled water, heating is boiled 1～2 hour, extracts; Merge No. three times extract, filter,Obtain filtrate, be condensed into the thick paste that at 60 DEG C, relative density is 1.10～1.13, for subsequent use;
(2) clean Ying Azulene, catchweed bedstraw herb, ball orchid and buckbean, and chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) macleaya cordata, rhizoma calami and Armilariella tabescens are put into container, carry out pulverization process, grind into powder, cross 160 order fine powders, for subsequent use;
(4) mountain Shen is cleaned, immerse 80% the alcohol solution dipping 1～2 hour of 3 times of amounts, heating is extracted 3 hours, reclaimsEthanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
(5) thizoma curculiginis is cleaned, is mixed thoroughly with yellow rice wine, run through rear slow fire and fry to micro-dry, take out and dry in the air to absolutely dry, be placed in mortar, grind into powder,Cross 200 order fine powders.
(6) above-mentioned steps (1)～(5) prepared thick paste, juice and fine powder are mixed, make capsule, obtain described controllingTreat the Chinese medicine preparation of tympanitis.
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