CN105582198A - Externally-applied powder for treating bone arthritis - Google Patents
Externally-applied powder for treating bone arthritis Download PDFInfo
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- CN105582198A CN105582198A CN201511030541.XA CN201511030541A CN105582198A CN 105582198 A CN105582198 A CN 105582198A CN 201511030541 A CN201511030541 A CN 201511030541A CN 105582198 A CN105582198 A CN 105582198A
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Abstract
The invention relates to externally-applied powder for treating bone arthritis. The externally-applied powder for treating bone arthritis comprises components in parts by weight as follows: 8-12 parts of common clubmoss herbs, 5-10 parts of kusnezoff monkshood roots, 15-20 parts of trogopterus dung, 5-10 parts of Gaultheria forrestii Diels, 9-13 parts of european verbena, 11-15 parts of earthworms, 9-13 parts of oriental waterplantain rhizomes, 19-23 parts of pubescent pepper herbs, 13-17 parts of natural indigo, 14-19 parts of Chinese eaglewood, 12-18 parts of abrotanum and 3-8 parts of south dodder seeds. The externally-applied powder has the advantages of short treatment course, fast effect, good curative effect and the like and does not cause side effect, dependence or drug resistance through reasonable matching of components of medicinal composition and adjuvant composition and mutual complementation and coordination of efficacy. The invention further provides a preparation method of the externally-applied powder for treating bone arthritis. The externally-applied powder is widely applied to prevention, control and treatment of bone joint pain resulting from various causes of diseases.
Description
Technical field
The present invention relates to a kind of Dressed medicine powder for the treatment of osteoarthritis and preparation method thereof.
Background technology
Osteoarthritis claims again degenerative joint disease, osteoarthropathy, senescent arthritis, hypertrophiarthritis etc.,The osteoproliferation that is commonly called as among the people. Be due to soft tissue sex change such as the cartilage that forms joint, interverbebral disc, ligaments, move backChange, edge, joint forms spur, and synovial membrane is plump waits variation, and occurs osteoclasia, causes that insecondary bone closesJoint is scorching, causes dysarthrasis to cause neck, lumbar vertebrae, the contraction of muscle arteries and veins, extremities joint distortion, numb limb pain,Seat bone neuralgia treating, the symptoms such as migraines. Osteoarthritis belongs to the category of the traditional Chinese medical science ' heumatism '. Heumatism be byHuman righteousness's deficiency or liver kidney two void, muscles and bones is lost in moistening foster, is subject to the outer evil channels and collaterals of invading such as wind, cold, wet,Cause channels and collaterals obturation, retardance joint, qi stagnation hemagglutination, with the passing of time causes dysarthrasis, enlargement, joint stuffiness,Numb pain, causes that muscular atrophy forms maimed person what is more. The treatment of osteoarthritis, doctor trained in Western medicine is mainly to relieve the painMedicine is to lead or beat anesthesia needle, as used indocin, and the medicines such as brufen, large to gastric irritation, side effect is large,Long-term use patient can not accept, and makes anesthesia needle and mainly uses procaine hydrochloride, prednisolone, although treatmentEffectively, but effect is undesirable, and what have takes operation, and What is more causes paraplegia, more allows the patient can notAccept. The traditional Chinese medical science is mainly used medicine and massage, acupuncture, and the therapies such as cup, existing Chinese Herbs is notToo desirable.
Summary of the invention
The technical problem to be solved in the present invention is the above-mentioned defect that how to overcome prior art, and a kind for the treatment of is providedThe Dressed medicine powder of osteoarthritis and the preparation method of powder thereof.
For solving the problems of the technologies described above, the Dressed medicine powder of this treatment osteoarthritis by following component according to shown in weightPart proportion is formulated, 8～12 parts of lycopodium calvatums, 5～10 parts of radix aconiti agrestis, 15～20 parts of excrementum pteropis, saturatingBone disappear 5～10 parts, 9～13 parts of Verbena officinalis, 11～15 parts of earthworms, 9～13 parts of, Mao Betel 19～23 of rhizoma alismatisPart, 13～17 parts of indigo naturalis, 14～19 parts of agalloch eaglewood, high 12～18 parts of green grass or young crops, 3～8 parts of the seed of Chinese dodders; Outside describedThe preparation method who applies powder is that ratio or formula measure each component by weight, and each component is pulverized as fragmentRear mistake 50 mesh sieves, obtain mixed-powder, in this mixed-powder with vinegar fried dry, the more fried 3～5h that adds water, windAfter dry, be ground into fine powder, cross 100 mesh sieves, sieve to such an extent that mixed-powder is the Dressed medicine powder of described treatment osteoarthritis.
As optimum ratio scope, described Dressed medicine powder by following component according to shown in weight ratio scope joinSystem forms, 9～11 parts of lycopodium calvatums, 7～9 parts of radix aconiti agrestis, 16～18 parts of excrementum pteropis, deep disappear 6～8 parts,10～12 parts of Verbena officinalis, 13～15 parts of earthworms, 20～22 parts of 11～13 parts of, Mao Betel of rhizoma alismatis, indigo naturalis 14～16Part, 17～19 parts of agalloch eaglewood, high 13～15 parts of green grass or young crops, 5～7 parts of the seed of Chinese dodders.
As concrete optimum ratio, described Dressed medicine powder by following component according to shown in weight ratio scope joinSystem forms, 9～11 parts of lycopodium calvatums, 7～9 parts of radix aconiti agrestis, 16～18 parts of excrementum pteropis, deep disappear 6～8 parts,10～12 parts of Verbena officinalis, 13～15 parts of earthworms, 20～22 parts of 11～13 parts of, Mao Betel of rhizoma alismatis, indigo naturalis 14～16Part, 17～19 parts of agalloch eaglewood, high 13～15 parts of green grass or young crops, 5～7 parts of the seed of Chinese dodders.
As concrete optimum ratio, described Dressed medicine powder by following component according to shown in weight ratio preparation andBecome, 8 parts of lycopodium calvatums, 10 parts of radix aconiti agrestis, 15 parts of excrementum pteropis, deep disappear 10 parts, 9 parts of Verbena officinalis,15 parts of earthworms, 23 parts of 9 parts of, Mao Betel of rhizoma alismatis, 13 parts of indigo naturalis, 19 parts of agalloch eaglewood, blue or green high 12 parts,8 parts of the seed of Chinese dodders.
As best proportioning, described Dressed medicine powder by following component according to shown in weight ratio formulated,10 parts of lycopodium calvatums, 8 parts of radix aconiti agrestis, 17 parts of excrementum pteropis, deep disappear 7 parts, 11 parts of Verbena officinalis, earthworm14 parts, 21 parts of 12 parts of, Mao Betel of rhizoma alismatis, 15 parts of indigo naturalis, 18 parts of agalloch eaglewood, blue or green high 14 parts, Tu silk6 parts of sons.
As concrete optimum ratio, described Dressed medicine powder by following component according to shown in weight ratio preparation andBecome, 11 parts of lycopodium calvatums, 7 parts of radix aconiti agrestis, 18 parts of excrementum pteropis, deep disappear 6 parts, 12 parts of Verbena officinalis,13 parts of earthworms, 20 parts of 13 parts of, Mao Betel of rhizoma alismatis, 16 parts of indigo naturalis, 17 parts of agalloch eaglewood, blue or green high 15 parts,5 parts of the seed of Chinese dodders.
As concrete optimum ratio, described Dressed medicine powder by following component according to shown in weight ratio preparation andBecome, 9 parts of lycopodium calvatums, 9 parts of radix aconiti agrestis, 16 parts of excrementum pteropis, deep disappear 8 parts, 10 parts of Verbena officinalis,15 parts of earthworms, 22 parts of 11 parts of, Mao Betel of rhizoma alismatis, 14 parts of indigo naturalis, 19 parts of agalloch eaglewood, blue or green high 13 parts,7 parts of the seed of Chinese dodders.
Pharmacological action
Lycopodium calvatum: mildly bitter flavor, pungent, warm in nature; Return liver,spleen,kidney warp; Dispel rheumatism, stimulate the circulation of the blood and cause the muscles and joints to relax; WithIn joint pain, joint stuffiness.
Radix aconiti agrestis: taste is pungent, hot in nature. Very toxic. Enter liver, the spleen channel. There is Eradicates rheumatism, eliminating cold to stop pain, detumescence.Control wind-cold-dampness arthralgia, arthralgia.
Excrementum pteropi: bitter, salty, sweet, ask. Return Liver Channel. Promoting blood circulation and stopping pain, removing blood stasis and hemostasis. For stagnation of blood stasisAll cards. Deep disappearing: taste is pungent, sweet, cold nature. Gas perfume (or spice). There is promoting blood circulation, myogenic knot bone, Li Shui is logicalDrench dampness removing removing jaundice, effect of the stasis of blood of dispelling cough-relieving.
Verbena officinalis: bitter, pungent, be slightly cold. Return liver, the spleen channel. Clearing heat and detoxicating, activating blood to promote menstruation, inducing diuresis for removing edema,Cut cruel. Cure mainly cold, fever, abscess of throat, swelling and aching of gum, jaundice, dysentery, blood stasis is through closing, dysmenorrhoea,Disorder lump in the abdomen, oedema, difficult urination, malaria, carbuncle pyogenic infections from tumour or sore, traumatic injury etc.
Earthworm: taste is salty, cold in nature. Enter stomach, spleen, liver, kidney channel. There is heat-clearing and stop convulsion, effect of dispelling, collateral-activating.
Rhizoma alismatis: taste is sweet, cold in nature, enter kidney, bladder two warps; Cure mainly clearing damp and promoting diuresis, this product slightly sweet flavor and cold in nature,The cold heat that can win sluices, and the light Li Shui that can ooze wets; Expel the heat-evil, rhizoma alismatis is cold in nature, and the heat-clearing of cold energy, enters kidney channel, can rush downKidney channel is fire mutually, can be used for seminal emission, tinnitus, the disease such as dizzy.
Mao Betel: taste is pungent, slightly warm in nature. Gas perfume (or spice). There is promoting qi circulation and relieving pain, effect of expelling wind and activating blood flow. For rheumatismWaist leg leads to and rheumatic arthritis.
Indigo naturalis: for salty, cold in nature; Return Liver Channel; Clearing heat and detoxicating, cool blood, arresting convulsion; For febrile virulent maculae, bloodHeat is told nosebleed, pectoralgia hemoptysis, aphtha, mumps, larynx numbness, pediatric epilepsy scared.
Corter pseudolaricis: taste is pungent, warm in nature, poisonous; Return lung, the spleen channel; Desinsection, antipruritic.
Blue or green high: bitter, pungent, cold in nature. Return liver, gallbladder channel. Function clearing away summerheat, except steaming, preventing malaria. For summer-heat evilHeating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to yin labor heat, malaria fever and chills, jaundice with damp-heat pathogen. .
The seed of Chinese dodder: warm in nature, taste is sweet; Return liver,kidney,spleen warp; Nourishing liver and kidney, controlling nocturnal emission with astringent drugs contracting urine, antiabortive, improving eyesight,Antidiarrheal. For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness and weakness of waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy,Fetal irritability, spleen kidney threatened abortion, fetal irritability, spleen are suffered from a deficiency of the kidney and are rushed down; Externally treating leucoderma.
The present invention is a kind of treats that the Dressed medicine powder of osteoarthritis is cheap, determined curative effect, passes through effective componentMutually supplement and coordinate with reasonable compatibility, effect of each component of assisting a ruler in governing a country composition, thering is short treating period, instant effect,Advantages such as good effect, and be pure natural crude drug compatibility, can not have side effects, dependence and the resistance to the action of a drug, thisInvention also provides the preparation method of the Dressed medicine powder of this treatment osteoarthritis, is widely used in the various causes of disease and drawsPrevention, control and the treatment of the bone joint pain rising.
Detailed description of the invention
Embodiment 1: described Dressed medicine powder by following component according to shown in weight ratio scope formulated,9～11 parts of lycopodium calvatums, 7～9 parts of radix aconiti agrestis, 16～18 parts of excrementum pteropis, deep disappear 6～8 parts, Verbena officinalis 10～12Part, 13～15 parts of earthworms, 20～22 parts of 11～13 parts of, Mao Betel of rhizoma alismatis, 14～16 parts of indigo naturalis, agalloch eaglewood 17～19Part, high 13～15 parts of green grass or young crops, 5～7 parts of the seed of Chinese dodders. Ratio or formula measure each component by weight, will be eachComponent is pulverized as crossing 50 mesh sieves after fragment, obtains mixed-powder, in this mixed-powder with vinegar fried dry, then addDecocting system 3～5h, is ground into fine powder after air-dry, crosses 100 mesh sieves, sieves to such an extent that mixed-powder is described treatment boneArthritic Dressed medicine powder A.
Embodiment 2: described Dressed medicine powder by following component according to shown in weight ratio formulated, stretch muscle8 parts of grass, 10 parts of radix aconiti agrestis, 15 parts of excrementum pteropis, deep disappear 10 parts, 9 parts of Verbena officinalis, earthworm 15Part, 23 parts of 9 parts of, Mao Betel of rhizoma alismatis, 13 parts of indigo naturalis, 19 parts of agalloch eaglewood, blue or green high 12 parts, the seed of Chinese dodder 8Part. Ratio or formula measure each component by weight, each component is pulverized as crossing 50 mesh sieves after fragment,Mixed-powder, in this mixed-powder with vinegar fried dry, the more fried 3～5h that adds water, is ground into fine powder after air-dry,Cross 100 mesh sieves, sieve to such an extent that mixed-powder is the Dressed medicine powder B of described treatment osteoarthritis.
Embodiment 3: described Dressed medicine powder by following component according to shown in weight ratio formulated, stretch muscle10 parts of grass, 8 parts of radix aconiti agrestis, 17 parts of excrementum pteropis, deep disappear 7 parts, 11 parts of Verbena officinalis, earthworm 14Part, 21 parts of 12 parts of, Mao Betel of rhizoma alismatis, 15 parts of indigo naturalis, 18 parts of agalloch eaglewood, blue or green high 14 parts, the seed of Chinese dodder6 parts. Ratio or formula measure each component by weight, each component is pulverized as crossing 50 mesh sieves after fragment,Mixed-powder, in this mixed-powder with vinegar fried dry, the more fried 3～5h that adds water, is ground into fine powder after air-dry,Cross 100 mesh sieves, sieve to such an extent that mixed-powder is the Dressed medicine powder C of described treatment osteoarthritis.
Embodiment 4: described Dressed medicine powder by following component according to shown in weight ratio formulated, stretch muscle11 parts of grass, 7 parts of radix aconiti agrestis, 18 parts of excrementum pteropis, deep disappear 6 parts, 12 parts of Verbena officinalis, earthworm 13Part, 20 parts of 13 parts of, Mao Betel of rhizoma alismatis, 16 parts of indigo naturalis, 17 parts of agalloch eaglewood, blue or green high 15 parts, the seed of Chinese dodder5 parts. Ratio or formula measure each component by weight, each component is pulverized as crossing 50 mesh sieves after fragment,Mixed-powder, in this mixed-powder with vinegar fried dry, the more fried 3～5h that adds water, is ground into fine powder after air-dry,Cross 100 mesh sieves, sieve to such an extent that mixed-powder is the Dressed medicine powder D of described treatment osteoarthritis.
Embodiment 5: described Dressed medicine powder by following component according to shown in weight ratio formulated, stretch muscle9 parts of grass, 9 parts of radix aconiti agrestis, 16 parts of excrementum pteropis, deep disappear 8 parts, 10 parts of Verbena officinalis, 15 parts of earthworms,22 parts of 11 parts of, Mao Betel of rhizoma alismatis, 14 parts of indigo naturalis, 19 parts of agalloch eaglewood, high 13 parts of green grass or young crops, 3 parts of the seed of Chinese dodders;Ratio or formula measure each component by weight, and each component is pulverized as crossing 50 mesh sieves after fragment, obtain mixingPowder, in this mixed-powder with vinegar fried dry, the more fried 3～5h that adds water, is ground into fine powder after air-dry, crosses 100Mesh sieve, sieves to such an extent that mixed-powder is the Dressed medicine powder E of described treatment osteoarthritis.
In above-mentioned fact Example, the Dressed medicine powder E effect of the treatment eczema that embodiment 3 makes is the most outstanding,For most preferred embodiment.
Clinical data
(1) case: acute, sub-anxious Human Osteoarthritis totally 191 examples that outpatient service is made a definite diagnosis.
(2) symptom: osteoarthritis pain.
(3) group setting: experimental group: 97 examples, the male sex's 58 examples, women's 38 examples, 14～56 years old age, flatEqual 36.5 years old. Control group: 94 examples, the male sex's 50 examples, women's 44 examples, 15～61 years old age, average 38.6 years old.
(4) curative effect is passed judgment on: recovery from illness: pain disappears; Effective: pain slows down 60～90%, symptom obviously changesKind; Take a turn for the better: aggravating activities is still with pain 20～59%, and symptom makes moderate progress; Invalid: pain still≤ 20%, symptom is without improvement. (6) result: two groups for the treatment of results (recovery from illness+effective be efficient), testGroup total effective rate is 95.12%, and control group group total effective rate is 63.75%, and there were significant differences to learn by statistics processing(P < 0.05), illustrates that treatment group curative effect is apparently higher than control group, and treatment group and control group ordinary circumstance, without aobviousWork difference, meets comparativity.
Above-mentioned embodiment is intended to illustrate the present invention and can be professional and technical personnel in the field's realization or use,It will be apparent for those skilled in the art that above-mentioned embodiment is modified, therefore thisInvention includes but not limited to above-mentioned embodiment, anyly meets these claims or description is described, and meetsWith principle disclosed herein and novelty, the method for inventive features, technique, product, all fall into thisWithin bright protection domain.
Claims (7)
1. a Dressed medicine powder for the treatment of osteoarthritis, is characterized in that: this medicine by following component according to instituteShow that weight ratio scope is formulated, 8～12 parts of lycopodium calvatums, 5～10 parts of radix aconiti agrestis, excrementum pteropi 15～20Part, deep disappear 5～10 parts, 9～13 parts of Verbena officinalis, 11～15 parts of earthworms, 9～13 parts of, Mao Betel of rhizoma alismatis3～8 parts of 19～23 parts, 13～17 parts of indigo naturalis, 14～19 parts of agalloch eaglewood, blue or green high 12～18 parts, the seed of Chinese dodder;The preparation method of described Dressed medicine powder is that ratio or formula measure each component by weight, and each component is pulverizedFor crossing 50 mesh sieves after fragment, obtain mixed-powder, in this mixed-powder with vinegar fried dry, the more fried 3～5h that adds water,After air-dry, be ground into fine powder, cross 100 mesh sieves, sieve mixed-powder to be the external application of described treatment osteoarthritis looseAgent.
2. the Dressed medicine powder for the treatment of osteoarthritis according to claim 1, is characterized in that: outside describedApply powder by following component according to shown in weight ratio scope formulated, 9～11 parts of lycopodium calvatums, radix aconiti agrestis7～9 parts, 16～18 parts of excrementum pteropis, deep disappear 6～8 parts, 10～12 parts of Verbena officinalis, 13～15 parts of earthworms,20～22 parts of 11～13 parts of, Mao Betel of rhizoma alismatis, 14～16 parts of indigo naturalis, 17～19 parts of agalloch eaglewood, blue or green high 13～155～7 parts of part, the seed of Chinese dodders.
3. the Dressed medicine powder for the treatment of osteoarthritis according to claim 2, is characterized in that: outside describedApply powder by following component according to shown in weight ratio formulated, 12 parts of lycopodium calvatums, 5 parts of radix aconiti agrestis,20 parts of excrementum pteropis, deep disappear 5 parts, 13 parts of Verbena officinalis, 11 parts of earthworms, 13 parts of, Mao Betel 19 of rhizoma alismatisPart, 17 parts of indigo naturalis, 14 parts of agalloch eaglewood, high 18 parts of green grass or young crops, 3 parts of the seed of Chinese dodders.
4. the Dressed medicine powder for the treatment of osteoarthritis according to claim 3, is characterized in that: outside describedApply powder by following component according to shown in weight ratio formulated, 8 parts of lycopodium calvatums, 10 parts of radix aconiti agrestis,15 parts of excrementum pteropis, deep disappear 10 parts, 9 parts of Verbena officinalis, 15 parts of earthworms, 9 parts of, Mao Betel 23 of rhizoma alismatisPart, 13 parts of indigo naturalis, 19 parts of agalloch eaglewood, high 12 parts of green grass or young crops, 8 parts of the seed of Chinese dodders.
5. the Dressed medicine powder for the treatment of osteoarthritis according to claim 4, is characterized in that: outside describedApply powder by following component according to shown in weight ratio formulated, 10 parts of lycopodium calvatums, 8 parts of radix aconiti agrestis,17 parts of excrementum pteropis, deep disappear 7 parts, 11 parts of Verbena officinalis, 14 parts of earthworms, 12 parts of, Mao Betel 21 of rhizoma alismatisPart, 15 parts of indigo naturalis, 18 parts of agalloch eaglewood, high 14 parts of green grass or young crops, 6 parts of the seed of Chinese dodders.
6. the Dressed medicine powder for the treatment of osteoarthritis according to claim 2, is characterized in that: outside describedApply powder by following component according to shown in weight ratio formulated, 11 parts of lycopodium calvatums, 7 parts of radix aconiti agrestis,18 parts of excrementum pteropis, deep disappear 6 parts, 12 parts of Verbena officinalis, 13 parts of earthworms, 13 parts of, Mao Betel 20 of rhizoma alismatisPart, 16 parts of indigo naturalis, 17 parts of agalloch eaglewood, high 15 parts of green grass or young crops, 5 parts of the seed of Chinese dodders.
7. the Dressed medicine powder for the treatment of osteoarthritis according to claim 2, is characterized in that: outside describedApply powder by following component according to shown in weight ratio formulated, 9 parts of lycopodium calvatums, 9 parts of radix aconiti agrestis,16 parts of excrementum pteropis, deep disappear 8 parts, 10 parts of Verbena officinalis, 15 parts of earthworms, 11 parts of, Mao Betel 22 of rhizoma alismatisPart, 14 parts of indigo naturalis, 19 parts of agalloch eaglewood, high 13 parts of green grass or young crops, 7 parts of the seed of Chinese dodders.
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