CN105560914A - 一种治疗肝肾亏虚型老年患者特发性震颤的中药 - Google Patents

一种治疗肝肾亏虚型老年患者特发性震颤的中药 Download PDF

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CN105560914A
CN105560914A CN201610102722.7A CN201610102722A CN105560914A CN 105560914 A CN105560914 A CN 105560914A CN 201610102722 A CN201610102722 A CN 201610102722A CN 105560914 A CN105560914 A CN 105560914A
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rhizoma
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李成君
吕洋
毕晓瑜
高凡淇
李潇桐
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Abstract

本发明公开了一种治疗肝肾亏虚型老年患者特发性震颤的中药，其是由以下重量份配比的中药原料制作而成的：女贞子10-15、黄精15-20、龟甲15-20、鳖甲15-20、当归15-20、牛膝10-15、川楝子6-10、菊花10-15、天麻6-10、桑叶10-15、香附10-15、阿胶10-15、山药15-20、甘草6-10、荆芥10-15、防风10-15、龙骨15-20、牡蛎15-20、丹参10-15、磁石15-30、朱砂0.3-0.5、五味子6-10。本发明各中药原料经辨证配伍，相互协同，共奏滋补肝肾、补益气血、平肝潜阳、宁心安神、熄风解痉之功效，对肝肾亏虚型老年患者特发性震颤的治疗效果显著，而且毒副作用小。

Description

一种治疗肝肾亏虚型老年患者特发性震颤的中药
技术领域
本发明涉及一种治疗肝肾亏虚型老年患者特发性震颤的中药，属于中药领域。
背景技术
特发性震颤又称家族性或良性特发性震颤，是临床常见的运动障碍性疾病，以姿势性或动作性震颤是惟一表现，缓慢进展或长期不进展。目前认为，年龄是特发性震颤重要的危险因素，患病率随年龄而增长。起病缓慢。任何年龄均可发病，但多起始于成年人，尤其是老年患者更多见。此病的西医治疗以心得安和氯硝西泮等药物为主，由于考虑到较多的毒副作用，许多老年患者不能接受。
发明内容
本发明的目的在于提供一种治疗肝肾亏虚型老年患者特发性震颤的中药。
本发明所采用的技术解决方案是：
一种治疗肝肾亏虚型老年患者特发性震颤的中药，其是由以下重量份配比的中药原料制作而成的：女贞子10-15、黄精15-20、龟甲15-20、鳖甲15-20、当归15-20、牛膝10-15、川楝子6-10、菊花10-15、天麻6-10、桑叶10-15、香附10-15、阿胶10-15、山药15-20、甘草6-10、荆芥10-15、防风10-15、龙骨15-20、牡蛎15-20、丹参10-15、磁石15-30、朱砂0.3-0.5、五味子6-10。
优选的，各中药原料的重量份配比为：女贞子12、黄精15、龟甲16、鳖甲17、当归16、牛膝12、川楝子7、菊花12、天麻8、桑叶12、香附10、阿胶15、山药15、甘草7、荆芥12、防风12、龙骨16、牡蛎16、丹参12、磁石20、朱砂0.4、五味子7。
上述中药可制备成汤剂，具体制备方法如下：
a按上述重量份配比称取各中药原料；
b将龟甲、鳖甲、牡蛎、龙骨、磁石分别粉碎，然后混合均匀，加适量水煎煮0.5-1小时；然后加入女贞子、黄精、当归、牛膝、川楝子、菊花、天麻、桑叶、香附、阿胶、山药、甘草、荆芥、防风、丹参、五味子，再加适量水继续煎煮0.5-1.5小时，过滤得煎煮液一与残渣；残渣再加适量水，加热煎煮0.5-1小时，过滤得煎煮液二；合并煎煮液一与煎煮液二，得到混合液；
c将朱砂研末，加入到步骤b制得的混合液中，调匀，得到中药汤剂。
本发明的药理及效果如下：
申请人经过多年的临床观察总结，发现肝肾亏虚型特发性震颤老年患者多见，此病由于阴血虚、肝血不足、血不养筋，肝风上扰所致。本发明通过精准辩证，精选中药，总结出一套治疗肝肾亏虚型老年患者特发性震颤的中药组合，取得了良好效果。本发明所选中药原料，龟甲、鳖甲、女贞子、黄精、五味子补益肝肾；龙骨、牡蛎平肝潜阳；荆芥、防风祛风解痉；牛膝、川楝子补肝肾、引火下行；阿胶、当归、山药补气血；天麻、桑叶平肝熄风；朱砂、磁石补肾除烦安神；香附理气；丹参活血通脉；菊花醒脑提神；甘草调和诸药。以上诸药配伍，相互协同，共奏滋补肝肾、补益气血、平肝潜阳、熄风解痉、除烦安神之功效，对肝肾亏虚型老年患者特发性震颤的治疗效果显著，而且毒副作用小。
临床资料
1.一般资料
选取2013年1月-2014年12月来院就诊的肝肾亏虚型特发性震颤老年患者50例进行临床观察治疗。其中男性29例，女性21例，年龄61-85岁。症见：颤振不愈，兼见头晕目眩，耳鸣，失眠多梦，腰酸脚软，肢体麻大，呆傻健忘，筋脉拘紧，动作笨拙。舌体偏瘦，舌质暗红少苔，脉细弦或沉细弦。
2.治疗方法
口服本发明中药汤剂，一日一剂，分早晚服用，1个月为1疗程。连续治疗3-5个疗程。
3.疗效评定标准
治愈：体征及症状完全改善，心情舒畅，精神焕发。
显效：体征及症状显著改善，心情舒畅，精神很好。
有效：体征及症状有改变，偶感稍有不适，但能接受。
无效：体征无改变，症状如前。
4.治疗结果
临床治愈46例，占92％；显效3例，占6％；有效1例，占2％；无效0例；总有效率100％。说明本发明中药汤剂对肝肾亏虚型老年患者特发性震颤治疗效果显著，值得更进一步临床推广。
典型病例
张某，男，67岁，患者2年前发现右手颤抖，不能做精细动作，后逐渐发展为四肢震颤、拘紧，步态不稳，伴盗汗，头晕目眩，失眠多梦，烦躁不安。诊断为肝肾亏虚型老年患者特发性震颤。服用本发明中药汤剂1个月后，以上症状明显好转，继续服用2个月后，复诊无明显震颤，情绪恢复正常，夜间睡眠较好，生活如常。疗效评定为治愈。
具体实施方式
实施例1
按下述重量份配比称取各中药原料：
女贞子12、黄精15、龟甲16、鳖甲17、当归16、牛膝12、川楝子7、菊花12、天麻8、桑叶12、香附10、阿胶15、山药15、甘草7、荆芥12、防风12、龙骨16、牡蛎16、丹参12、磁石20、朱砂0.4、五味子7。
制备方法如下：
将龟甲、鳖甲、牡蛎、龙骨、磁石分别粉碎，然后混合均匀，加龟甲、鳖甲、牡蛎、龙骨与磁石总用量5倍重量的水煎煮1小时。然后加入女贞子、黄精、当归、牛膝、川楝子、菊花、天麻、桑叶、香附、阿胶、山药、甘草、荆芥、防风、丹参、五味子，再加以上所有原料药总用量8倍重量水继续煎煮1小时，过滤得煎煮液一与残渣。残渣再加以上所有原料药总用量8倍重量水，加热煎煮0.5小时，过滤得煎煮液二。合并煎煮液一与煎煮液二，得到混合液。将朱砂研末，加入到上述混合液中，调匀，得到中药汤剂。
实施例2
按下述重量份配比称取各中药原料：
女贞子10、黄精15、龟甲15、鳖甲20、当归15、牛膝10、川楝子10、菊花10、天麻10、桑叶10、香附15、阿胶10、山药20、甘草6、荆芥10、防风15、龙骨15、牡蛎15、丹参15、磁石15、朱砂0.3、五味子6。
制备方法同实施例1。
实施例3
按下述重量份配比称取各中药原料：
女贞子15、黄精20、龟甲20、鳖甲15、当归20、牛膝15、川楝子6、菊花15、天麻6、桑叶15、香附10、阿胶15、山药15、甘草10、荆芥15、防风10、龙骨20、牡蛎20、丹参10、磁石30、朱砂0.5、五味子10。
制备方法同实施例1。

Claims (2)

1.一种治疗肝肾亏虚型老年患者特发性震颤的中药，其特征在于它是由以下重量份配比的中药原料制作而成的：女贞子10-15、黄精15-20、龟甲15-20、鳖甲15-20、当归15-20、牛膝10-15、川楝子6-10、菊花10-15、天麻6-10、桑叶10-15、香附10-15、阿胶10-15、山药15-20、甘草6-10、荆芥10-15、防风10-15、龙骨15-20、牡蛎15-20、丹参10-15、磁石15-30、朱砂0.3-0.5、五味子6-10。
2.根据权利要求1所述的一种治疗肝肾亏虚型老年患者特发性震颤的中药，其特征在于各中药原料的重量份配比为：女贞子12、黄精15、龟甲16、鳖甲17、当归16、牛膝12、川楝子7、菊花12、天麻8、桑叶12、香附10、阿胶15、山药15、甘草7、荆芥12、防风12、龙骨16、牡蛎16、丹参12、磁石20、朱砂0.4、五味子7。
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Publication number Priority date Publication date Assignee Title
CN1178695A (zh) * 1997-07-14 1998-04-15 迟经惠 震颤摇头安
CN101810808A (zh) * 2010-05-26 2010-08-25 泰一和浦（北京）中医药研究院有限公司 一种治疗震颤的中药组合物及其制备方法
CN102872320A (zh) * 2011-07-14 2013-01-16 张仲辉 一种治疗肝昌阴虚所致震颤麻痹的中药方
CN104524328A (zh) * 2014-12-15 2015-04-22 陈中元 一种治疗震颤病的药物及其制备

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1178695A (zh) * 1997-07-14 1998-04-15 迟经惠 震颤摇头安
CN101810808A (zh) * 2010-05-26 2010-08-25 泰一和浦（北京）中医药研究院有限公司 一种治疗震颤的中药组合物及其制备方法
CN102872320A (zh) * 2011-07-14 2013-01-16 张仲辉 一种治疗肝昌阴虚所致震颤麻痹的中药方
CN104524328A (zh) * 2014-12-15 2015-04-22 陈中元 一种治疗震颤病的药物及其制备

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