CN105560690A - Traditional Chinese medicinal ointment for treating fracture healing, and preparation method thereof - Google Patents

Traditional Chinese medicinal ointment for treating fracture healing, and preparation method thereof Download PDF

Info

Publication number
CN105560690A
CN105560690A CN201511026112.5A CN201511026112A CN105560690A CN 105560690 A CN105560690 A CN 105560690A CN 201511026112 A CN201511026112 A CN 201511026112A CN 105560690 A CN105560690 A CN 105560690A
Authority
CN
China
Prior art keywords
parts
radix
water
traditional chinese
fracture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201511026112.5A
Other languages
Chinese (zh)
Inventor
刘喜全
修海波
隋光善
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201511026112.5A priority Critical patent/CN105560690A/en
Publication of CN105560690A publication Critical patent/CN105560690A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • A61K36/126Drynaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/55Liquid-liquid separation; Phase separation

Abstract

The invention belongs to the field of traditional Chinese medicines, and especially relates to a traditional Chinese medicinal ointment for treating fracture healing, and a preparation method thereof. The ointment is prepared from, by weight, 6-8 parts of aconite root, 6-8 parts of cinnamon, 6-8 parts of natural copper, 4-6 parts of reddle, 10-15 parts of red bean, 10-15 parts of dragon's blood, 10-15 parts of Chinese angelica root, 10-15 parts of Boswellia carteri, 10-15 parts of myrrh, 15-20 parts of panax notoginseng powder, 8-10 parts of ground beetle, 8-10 parts of pilose antler, 15-20 parts of epimeddium, 8-10 parts of Nux Vomica, 1-3 parts of musk, 1-3 parts of Root of Younghusband Jerusalemsage, 3-5 parts of rhizoma drynariae, 15-20 parts of Herba Taraxaci, 1-3 parts of Sciurotamias daoidianus Milne-Edwards, 10-15 parts of Incised Notopterygium and 10-15 parts of Radix Angelicae Pubescentis. The above traditional Chinese medicine can activate blood circulation, dissipate blood stasis, move qi, dispel wind, eliminate swelling, relieve pains, clear heat, detoxify, promote tissue regeneration, relax veins, set fracture, improve blood circulation, remove necrotic tissues, increase the quality of osteoblasts and osteoclasts, promote fracture healing and mitigate patients' pains.

Description

A kind of traditional Chinese herb medicine promoting union of fracture and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind of traditional Chinese herb medicine promoting union of fracture and preparation method thereof.
Background technology
Fracture means the one disease because the reason such as wound or pathology causes bone parts ground or fully ruptures.Its main clinical manifestation is that fracture site has localized pain and tenderness, local swelling and occur ecchymosis, limb function position or completely lose, and complete fracture still can occur cacomelia and abnormal movement.Union of fracture is the osteanagenesis repair process of and complexity, be subject to multifactorial impact and the adjustment perhaps of whole body and local, the fracture of about 5% ~ 10% is due to a variety of causes generation delayed union or disunion, have a strong impact on the life quality of people, how accelerating union of bone fracture, improve healing quality is the problem that medical circle is paid close attention to jointly always.
The types of drugs of current treatment fracture is a lot, but effect is not fairly obvious, and treatment cycle is longer, easily intersects repeated infection, and use inconvenience, untoward reaction is many.If do not have timely and effective process, meeting delay treatment, easily cause sequela, conventional treatment is cleaned again, causes patient painful again.
Summary of the invention
According to the deficiencies in the prior art, the invention provides one can blood circulation promoting and blood stasis dispelling, and circulation of qi promoting is dispeled the wind, reducing swelling and alleviating pain, heat-clearing and toxic substances removing, the synthetism of granulation promoting dredging collateral, promotes the Chinese medicine formula of union of fracture and the preparation method of ointment thereof.
A kind of traditional Chinese herb medicine promoting union of fracture disclosed in this invention, formulated by the raw material of Chinese medicine of following parts by weight: Radix Aconiti Lateralis Preparata 6-8 part, Cortex Cinnamomi 6-8 part, Pyritum 6-8 part, Haematitum 4-6 part, Semen Phaseoli 10-15 part, Sanguis Draxonis 10-15 part, Radix Angelicae Sinensis 10-15 part, Olibanum 10-15 part, Myrrha 10-15 part, Radix Notoginseng powder 15-20 part, Eupolyphaga Seu Steleophaga 8-10 part, Cornu Cervi Pantotrichum 8-10 part, Herba Epimedii 15-20 part, Semen Strychni 8-10 part, Moschus 1-3 part, Radix phlomidis younghusbandii 1-3 part, Rhizoma Drynariae 3-5 part, Herba Taraxaci 15-20 part, Sciurotamias daoidianus Milne-Edwards 1-3 part, Rhizoma Et Radix Notopterygii 10-15 part, Radix Angelicae Pubescentis 10-15 part.
Promote a traditional Chinese herb medicine for union of fracture, preferably formulated by the raw material of Chinese medicine of following parts by weight: Radix Aconiti Lateralis Preparata 7 parts, Cortex Cinnamomi 7 parts, Pyritum 7 parts, Haematitum 5 parts, Semen Phaseoli 13 parts, Sanguis Draxonis 12 parts, Radix Angelicae Sinensis 13 parts, Olibanum 12 parts, Myrrha 12 parts, Radix Notoginseng powder 17 parts, Eupolyphaga Seu Steleophaga 9 parts, 9 parts, Cornu Cervi Pantotrichum, Herba Epimedii 16 parts, Semen Strychni 9 parts, 2 parts, Moschus, Radix phlomidis younghusbandii 2 parts, Rhizoma Drynariae 4 parts, Herba Taraxaci 17 parts, Sciurotamias daoidianus Milne-Edwards 2 parts, Rhizoma Et Radix Notopterygii 12 parts, Radix Angelicae Pubescentis 13 parts.
Promote a preparation method for the traditional Chinese herb medicine of union of fracture, step is as follows: get above-mentioned formula Chinese medicine and clean roguing, add water and cover powder 2-4cm, soak 1-1.2h, pull medical material out and put during multi-functional extractions is filled with and decoct with water secondary, the water of first time totalling medical material 10-13 times amount, decoct 2h, get decocting liquid, filter, second time adds up the water of medical material 8-10 times amount, decoct 1-2h, get twice decocting liquid to merge, filter, when being concentrated into 65 DEG C, relative density is the concentrated solution of 1.05; Adding ethanol in proper amount makes alcohol content reach 75%, and filter, filtrate recycling ethanol is also concentrated into the extractum that relative density is 1.10; Take stearic acid 2.0 kilograms and liquid paraffin 9.0 kilograms, put heated and stirred on water-bath and do oil phase to fine melt, about 70 DEG C insulations; Separately get glycerol 5 liters, triethanolamine 0.4 kilogram, distilled water 50 liters, on water-bath, aqueous phase is done in heating, adds in aqueous phase by above-mentioned water extract-alcohol precipitation extractum, 70 DEG C of insulations, gently add oil phase in aqueous phase and ceaselessly stir, until during cooling 45 DEG C, continue to stir, fill.
Using method: the morning, noon and afternoon respectively smear fracture face once.It within 10 days, is a course for the treatment of.
Pharmacology analysis:
Radix Aconiti Lateralis Preparata: acrid in the mouth, sweet, extremely hot in nature is poisonous.GUIXIN, kidney, spleen channel.Can recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, by wind-cold damp pathogen.For YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
Cortex Cinnamomi: acrid in the mouth, sweet, extremely hot in nature.Return kidney, spleen, the heart, Liver Channel.Fire can be mended supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.For sexual impotence, cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, dizziness due to yang deficiency, conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, and deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.
Pyritum: acrid in the mouth, property is put down.Return Liver Channel.Can dissipating blood stasis, synthetism, pain relieving.For tumbling and swelling, injured bone.
Haematitum: bitter in the mouth, sweet, property is put down.Return liver, stomach, heart born of the same parents warp.Can suppressing the hyperactive liver town inverse, cooling blood for hemostasis.For eructation vomiting, dysphagia and regurgitation, asthma, infantile convulsion, spits blood, epistaxis, hemorrhoidal hamorrhage, hemorrhoid complicated by anal fistula, bleeding not during menses.
Semen Phaseoli: sweet in the mouth, acid, property is put down.GUIXIN, small intestine meridian.Can inducing diuresis to remove edema, removing toxic substances and promoting pus discharge.For edema distension, beriberi limb swells, jaundice dark coloured urine, beriberoid pyretic arthralgia, carbuncle sore tumefacting virus, abdominalgia with intestinal abscess.
Sanguis Draxonis: sweet in the mouth, salty, property is put down.GUIXIN, Liver Channel.Can removing blood stasis and relieving pain, hemostasia and promoting granulation.Lose for falling to flutter, ecchymoma due to internal injury; Continuous bleeding due to traumatic injury.
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature.Return liver, the heart, spleen channel.Can enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Olibanum: acrid in the mouth, hardship, warm in nature.GUIXIN, liver, spleen channel.Can promoting blood circulation and stopping pain.For all pains of trusted subordinate, the contracture of muscle arteries and veins, traumatic injury, sore, carbuncle and painful swelling; Externally used detumescence granulation promoting.
Myrrha: bitter in the mouth, property is put down.Return Liver Channel.Can eliminating stasis to stop pain, externally used detumescence granulation promoting.Swell and ache for traumatic injury congestion, ulcer sore pain, all pains of breast abdomen.
Radix Notoginseng powder: sweet in the mouth, micro-hardship, warm in nature.Return liver, stomach warp.Can stop blooding by dissipating blood stasis, subduing swelling and relieving pain.For spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, and breast abdomen twinges, tumbling and swelling.
Eupolyphaga Seu Steleophaga: salty in the mouth, cold in nature, slightly poisonous.Return Liver Channel.Can removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.
Cornu Cervi Pantotrichum: sweet in the mouth, salty, warm in nature.Return kidney, Liver Channel.Can invigorating kidney-YANG, benefiting essence-blood, bone and muscle strengthening, adjusts punching to appoint, holder sore.For sexual impotence spermatorrhea, cold womb is infertile, weakness and emaciation, Mental fatigue, fear of cold, and vertigo and tinnitus is deaf, and spinal column cold type of pain, muscles and bones flaccidity is soft, bleeding not during menses, and carbuncle of yin nature is not held back.
Herba Epimedii: acrid in the mouth, sweet, warm in nature.Return liver, kidney channel.Can kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
Semen Strychni: bitter in the mouth, warm in nature, very toxic.Return liver, spleen channel.Can removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.For rheumatoid arthritis stubborn, paralysis and numbness, injury from falling down, ulcer sore pain.
Moschus: acrid in the mouth, warm in nature.GUIXIN, spleen channel.Can to have one's ideas straightened out refreshment, promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain.For calentura coma, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, amenorrhea , WEIJIA, difficult labour stillborn fetus, trusted subordinate's sudden pain, carbuncle scrofula, and laryngopharynx swelling and pain, falls and flutter the pain of injury, and arthralgia pain is numb.
Radix phlomidis younghusbandii: sweet in the mouth, property is put down.Can relieving cough and reducing sputum, clearing away heat and cooling blood.For cold cough, bronchitis, and control skin ulcer of a specified duration and do not heal.
Rhizoma Drynariae: bitter in the mouth, warm in nature.Return kidney, Liver Channel.Can the kidney invigorating bone strengthening, continuously hinder pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone.
Herba Taraxaci: bitter in the mouth, sweet, cold in nature.Return liver, stomach warp.Can heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Sciurotamias daoidianus Milne-Edwards: sweet in the mouth, salty, property is put down.Return Liver Channel.Can promoting blood circulation and stopping pain.Main traumatic injury pain, fracture, waist lower limb arthralgia pain.
Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature.Return bladder, kidney channel.Can cold expelling, dispel the wind, dehumidifying, pain relieving.For anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.
Radix Angelicae Pubescentis: acrid in the mouth, hardship, slightly warm in nature.Return kidney, urinary bladder channel.Can expelling wind and removing dampness, numbness relieving and pain relieving.For anemofrigid-damp arthralgia, lumbocrural pain, few cloudy volt wind headache.
Chinese medicine of the present invention can blood circulation promoting and blood stasis dispelling, and circulation of qi promoting is dispeled the wind, reducing swelling and alleviating pain, heat-clearing and toxic substances removing, and the synthetism of granulation promoting dredging collateral, improves blood circulation, removes slough, increases osteoblast and amount of osteoclast, promotes union of fracture, alleviates the misery of patient.
Now collect 635 fracture patients, use this ointment, the morning, noon and afternoon respectively smear fracture face once.
Outcome measure:
Effective: healing time at least shifts to an earlier date 1/3, and fracture reaches clinical healing standard.
Effective: union of fracture pre-set time is 1/5-1/4, fracture reaches clinical healing standard.
Invalid: healing time is no significant difference compared with normal healing time.
It within 10 days, is a course for the treatment of.After using 3 course for the treatment of traditional Chinese herb medicines of the present invention, statistical result is as follows:
Case load Effective number Obvious effective rate Significant figure Invalid number Total effective rate
600 468 78% 94 38 93.7%
As seen from the above table, after pharmaceutical treatment of the present invention, effective 468 examples, account for 78%, and effective 94 examples, account for 15.7%, and invalid 38 examples, account for 6.3%, overall efficiency is 93.7%.As can be seen here, the present invention has good effect to promotion union of fracture.
Attached several routine case is described further:
Case 1:
Week certain, man, 45 years old, because contingency causes right lower limb Tibia-fibula fracture, after hospital resets, adopts plaster fixing and conventional therapy, treat swelling after 10 days and disappear, but the display of X sheet has no callus generation.Rear employing plintlet is fixed, and smears traditional Chinese herb medicine of the present invention outward, medication 30 days, and the visible primary callus of X sheet generates substantially, continues medication the 40th day bone trabecula by fracture line, follows up a case by regular visits to without recurrence.
Case 2:
Zhu, female, 28 years old, left chi, scratches bone closed fracture, and right hand upper end breaking property is fractured, and carry out operative reduction, plintlet is fixed, and smears traditional Chinese herb medicine of the present invention outward.Medication elimination of swelling and ache in the 5th day, pain obviously alleviates, and within the 15th day, the visible primary callus of x-ray generates, and rehabilitation of healing completely in the 40th day follows up a case by regular visits to two months without recurrence.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in detail, but the present invention is not limited to specific embodiment.
Embodiment 1:
Promote a traditional Chinese herb medicine for union of fracture, formulated by the raw material of Chinese medicine of following parts by weight: Radix Aconiti Lateralis Preparata 8 parts, Cortex Cinnamomi 6 parts, Pyritum 8 parts, Haematitum 4 parts, Semen Phaseoli 15 parts, Sanguis Draxonis 10 parts, Radix Angelicae Sinensis 15 parts, Olibanum 10 parts, Myrrha 15 parts, Radix Notoginseng powder 15 parts, Eupolyphaga Seu Steleophaga 10 parts, 8 parts, Cornu Cervi Pantotrichum, Herba Epimedii 20 parts, Semen Strychni 8 parts, 3 parts, Moschus, Radix phlomidis younghusbandii 1 part, Rhizoma Drynariae 5 parts, Herba Taraxaci 15 parts, Sciurotamias daoidianus Milne-Edwards 3 parts, Rhizoma Et Radix Notopterygii 10 parts, Radix Angelicae Pubescentis 15 parts.
Embodiment 2:
Promote a traditional Chinese herb medicine for union of fracture, formulated by the raw material of Chinese medicine of following parts by weight: Radix Aconiti Lateralis Preparata 6 parts, Cortex Cinnamomi 8 parts, Pyritum 6 parts, Haematitum 6 parts, Semen Phaseoli 10 parts, Sanguis Draxonis 15 parts, Radix Angelicae Sinensis 10 parts, Olibanum 15 parts, Myrrha 10 parts, Radix Notoginseng powder 20 parts, Eupolyphaga Seu Steleophaga 8 parts, 10 parts, Cornu Cervi Pantotrichum, Herba Epimedii 15 parts, Semen Strychni 10 parts, 1 part, Moschus, Radix phlomidis younghusbandii 3 parts, Rhizoma Drynariae 3 parts, Herba Taraxaci 20 parts, Sciurotamias daoidianus Milne-Edwards 1 part, Rhizoma Et Radix Notopterygii 15 parts, Radix Angelicae Pubescentis 10 parts.
Embodiment 3:
Promote a traditional Chinese herb medicine for union of fracture, formulated by the raw material of Chinese medicine of following parts by weight: Radix Aconiti Lateralis Preparata 7 parts, Cortex Cinnamomi 7 parts, Pyritum 7 parts, Haematitum 5 parts, Semen Phaseoli 13 parts, Sanguis Draxonis 12 parts, Radix Angelicae Sinensis 13 parts, Olibanum 12 parts, Myrrha 12 parts, Radix Notoginseng powder 17 parts, Eupolyphaga Seu Steleophaga 9 parts, 9 parts, Cornu Cervi Pantotrichum, Herba Epimedii 16 parts, Semen Strychni 9 parts, 2 parts, Moschus, Radix phlomidis younghusbandii 2 parts, Rhizoma Drynariae 4 parts, Herba Taraxaci 17 parts, Sciurotamias daoidianus Milne-Edwards 2 parts, Rhizoma Et Radix Notopterygii 12 parts, Radix Angelicae Pubescentis 13 parts.
Embodiment 4:
Promote a preparation method for the traditional Chinese herb medicine of union of fracture, step is as follows: choose each component of medicine in the ratio of embodiment 1, cleans roguing, add water and cover powder 2cm, soak 1h, pull out medical material put multi-functional extractions filling in decoct with water secondary, add up the water of medical material 10 times amount for the first time, decoct 2h, get decocting liquid, filter, second time adds up the water of medical material 8 times amount, decocts 1h, gets twice decocting liquid and merges, filter, when being concentrated into 65 DEG C, relative density is the concentrated solution of 1.05; Adding ethanol in proper amount makes alcohol content reach 75%, and filter, filtrate recycling ethanol is also concentrated into the extractum that relative density is 1.10; Take stearic acid 2.0 kilograms and liquid paraffin 9.0 kilograms, put heated and stirred on water-bath and do oil phase to fine melt, about 70 DEG C insulations; Separately get glycerol 5 liters, triethanolamine 0.4 kilogram, distilled water 50 liters, on water-bath, aqueous phase is done in heating, adds in aqueous phase by above-mentioned water extract-alcohol precipitation extractum, 70 DEG C of insulations, gently add oil phase in aqueous phase and ceaselessly stir, until during cooling 45 DEG C, continue to stir, fill.
Instructions of taking: the morning, noon and afternoon respectively smear fracture face once.It within 10 days, is a course for the treatment of.
Embodiment 5:
Promote a preparation method for the traditional Chinese herb medicine of union of fracture, step is as follows: choose each component of medicine in the ratio of embodiment 2, cleans roguing, add water and cover powder 4cm, soak 1.2h, pull out medical material put multi-functional extractions filling in decoct with water secondary, add up the water of medical material 13 times amount for the first time, decoct 2h, get decocting liquid, filter, second time adds up the water of medical material 10 times amount, decocts 2h, gets twice decocting liquid and merges, filter, when being concentrated into 65 DEG C, relative density is the concentrated solution of 1.05; Adding ethanol in proper amount makes alcohol content reach 75%, and filter, filtrate recycling ethanol is also concentrated into the extractum that relative density is 1.10; Take stearic acid 2.0 kilograms and liquid paraffin 9.0 kilograms, put heated and stirred on water-bath and do oil phase to fine melt, about 70 DEG C insulations; Separately get glycerol 5 liters, triethanolamine 0.4 kilogram, distilled water 50 liters, on water-bath, aqueous phase is done in heating, adds in aqueous phase by above-mentioned water extract-alcohol precipitation extractum, 70 DEG C of insulations, gently add oil phase in aqueous phase and ceaselessly stir, until during cooling 45 DEG C, continue to stir, fill.
Instructions of taking: the morning, noon and afternoon respectively smear fracture face once.It within 10 days, is a course for the treatment of.
Embodiment 6:
Promote a preparation method for the traditional Chinese herb medicine of union of fracture, step is as follows: choose each component of medicine in the ratio of embodiment 3, cleans roguing, add water and cover powder 3cm, soak 1.1h, pull out medical material put multi-functional extractions filling in decoct with water secondary, add up the water of medical material 12 times amount for the first time, decoct 2h, get decocting liquid, filter, second time adds up the water of medical material 9 times amount, decocts 1.5h, gets twice decocting liquid and merges, filter, when being concentrated into 65 DEG C, relative density is the concentrated solution of 1.05; Adding ethanol in proper amount makes alcohol content reach 75%, and filter, filtrate recycling ethanol is also concentrated into the extractum that relative density is 1.10; Take stearic acid 2.0 kilograms and liquid paraffin 9.0 kilograms, put heated and stirred on water-bath and do oil phase to fine melt, about 70 DEG C insulations; Separately get glycerol 5 liters, triethanolamine 0.4 kilogram, distilled water 50 liters, on water-bath, aqueous phase is done in heating, adds in aqueous phase by above-mentioned water extract-alcohol precipitation extractum, 70 DEG C of insulations, gently add oil phase in aqueous phase and ceaselessly stir, until during cooling 45 DEG C, continue to stir, fill.
Instructions of taking: the morning, noon and afternoon respectively smear fracture face once.Within 10 days, be one the course for the treatment of journey.
Below the present invention be described in detail, the above, be only the preferred embodiment of the present invention, when not limiting the scope of the present invention, namely allly does impartial change according to the application's scope and modify, all should still belong in covering scope of the present invention.

Claims (3)

1. one kind promotes the traditional Chinese herb medicine of union of fracture, it is characterized in that, formulated by the raw material of Chinese medicine of following parts by weight: Radix Aconiti Lateralis Preparata 6-8 part, Cortex Cinnamomi 6-8 part, Pyritum 6-8 part, Haematitum 4-6 part, Semen Phaseoli 10-15 part, Sanguis Draxonis 10-15 part, Radix Angelicae Sinensis 10-15 part, Olibanum 10-15 part, Myrrha 10-15 part, Radix Notoginseng powder 15-20 part, Eupolyphaga Seu Steleophaga 8-10 part, Cornu Cervi Pantotrichum 8-10 part, Herba Epimedii 15-20 part, Semen Strychni 8-10 part, Moschus 1-3 part, Radix phlomidis younghusbandii 1-3 part, Rhizoma Drynariae 3-5 part, Herba Taraxaci 15-20 part, Sciurotamias daoidianus Milne-Edwards 1-3 part, Rhizoma Et Radix Notopterygii 10-15 part, Radix Angelicae Pubescentis 10-15 part.
2. a kind of traditional Chinese herb medicine promoting union of fracture according to claim 1, is characterized in that, formulated by the raw material of Chinese medicine of following parts by weight: Radix Aconiti Lateralis Preparata 7 parts, Cortex Cinnamomi 7 parts, Pyritum 7 parts, Haematitum 5 parts, Semen Phaseoli 13 parts, Sanguis Draxonis 12 parts, Radix Angelicae Sinensis 13 parts, Olibanum 12 parts, Myrrha 12 parts, Radix Notoginseng powder 17 parts, Eupolyphaga Seu Steleophaga 9 parts, 9 parts, Cornu Cervi Pantotrichum, Herba Epimedii 16 parts, Semen Strychni 9 parts, 2 parts, Moschus, Radix phlomidis younghusbandii 2 parts, Rhizoma Drynariae 4 parts, Herba Taraxaci 17 parts, Sciurotamias daoidianus Milne-Edwards 2 parts, Rhizoma Et Radix Notopterygii 12 parts, Radix Angelicae Pubescentis 13 parts.
3. the preparation method of the traditional Chinese herb medicine of a promotion union of fracture according to claim 1, it is characterized in that step is as follows: get above-mentioned formula Chinese medicine and clean roguing, add water and cover powder 2-4cm, soak 1-1.2h, pull out medical material put multi-functional extraction fill with in decoct with water secondary, the water of first time totalling medical material 10-13 times amount, decoct 2h, get decocting liquid, filter, second time adds up the water of medical material 8-10 times amount, decoct 1-2h, get twice decocting liquid to merge, filter, when being concentrated into 65 DEG C, relative density is the concentrated solution of 1.05; Adding ethanol in proper amount makes alcohol content reach 75%, and filter, filtrate recycling ethanol is also concentrated into the extractum that relative density is 1.10; Take stearic acid 2.0 kilograms and liquid paraffin 9.0 kilograms, put heated and stirred on water-bath and do oil phase to fine melt, about 70 DEG C insulations; Separately get glycerol 5 liters, triethanolamine 0.4 kilogram, distilled water 50 liters, on water-bath, aqueous phase is done in heating, adds in aqueous phase by above-mentioned water extract-alcohol precipitation extractum, 70 DEG C of insulations, gently add oil phase in aqueous phase and ceaselessly stir, until during cooling 45 DEG C, continue to stir, fill.
CN201511026112.5A 2015-12-30 2015-12-30 Traditional Chinese medicinal ointment for treating fracture healing, and preparation method thereof Pending CN105560690A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201511026112.5A CN105560690A (en) 2015-12-30 2015-12-30 Traditional Chinese medicinal ointment for treating fracture healing, and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201511026112.5A CN105560690A (en) 2015-12-30 2015-12-30 Traditional Chinese medicinal ointment for treating fracture healing, and preparation method thereof

Publications (1)

Publication Number Publication Date
CN105560690A true CN105560690A (en) 2016-05-11

Family

ID=55871702

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201511026112.5A Pending CN105560690A (en) 2015-12-30 2015-12-30 Traditional Chinese medicinal ointment for treating fracture healing, and preparation method thereof

Country Status (1)

Country Link
CN (1) CN105560690A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106266426A (en) * 2016-05-28 2017-01-04 张伟 A kind of externally applied liniment treating fracture

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1096208A (en) * 1993-06-09 1994-12-14 朱建防 Removing sludging bone junction powder
CN1101273A (en) * 1994-01-12 1995-04-12 杨延庆 Chinese medicine plaster for setting of fracture
CN1106279A (en) * 1994-02-05 1995-08-09 李克祥 Painless bonesetting medicine
CN103230506A (en) * 2013-05-14 2013-08-07 刘瑞平 Bone-setting medicament

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1096208A (en) * 1993-06-09 1994-12-14 朱建防 Removing sludging bone junction powder
CN1101273A (en) * 1994-01-12 1995-04-12 杨延庆 Chinese medicine plaster for setting of fracture
CN1106279A (en) * 1994-02-05 1995-08-09 李克祥 Painless bonesetting medicine
CN103230506A (en) * 2013-05-14 2013-08-07 刘瑞平 Bone-setting medicament

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106266426A (en) * 2016-05-28 2017-01-04 张伟 A kind of externally applied liniment treating fracture

Similar Documents

Publication Publication Date Title
CN102988657B (en) Plaster for treating fracture and traumatic injury and preparation method of plaster
CN104958484A (en) traditional Chinese medicine unguent for promoting blood circulation to remove meridian obstruction and preparing method of traditional Chinese medicine unguent
CN102258658A (en) Plaster for invigorating blood circulation and relieving pain
CN104189871A (en) Medicated wine for treating osteoproliferation
CN105288545A (en) Traditional Chinese medicine unguent warming yang, dredging collaterals, activating blood and stopping pain and preparation method thereof
CN100534497C (en) External ointment for treating bone fracture
CN101264146B (en) Externally-applied Chinese herbal medicine for treating bones and muscles disease and preparation thereof
CN105079184A (en) Medicine for treating osteoporosis
CN102580011B (en) Navel fumigating traditional Chinese medicine composition for treating prostatitis
CN105709074A (en) Medicine for treating rheumatic arthritis and hyperostosis and preparation method
CN102772699B (en) Traditional Chinese medicine composition for treating chronic pelvic inflammatory disease
CN105560690A (en) Traditional Chinese medicinal ointment for treating fracture healing, and preparation method thereof
CN104225490A (en) Traditional Chinese medicine for treating cholecystitis
CN103893611A (en) Drug for treating kidney stone and preparation method of drug
CN102349980A (en) Traditional Chinese medicine for treating rheumatism
CN102416049B (en) Small square type rheumatoid swelling diminishing and pain eliminating plaster and preparation method thereof
CN105497779A (en) Traditional Chinese medicine patch for treating acute lumbar sprain
CN103432311B (en) The Chinese medicine composition of traditional Chinese medicine fumigating moxibustion therapy treatment ankylosing spondylitis
CN103845547A (en) Traditional Chinese medicine decoction for treating mumps
CN102935157B (en) Chinese medicinal ointment for treating closed fracture
CN103463233B (en) Traditional Chinese medicine fumigation composition used for treating bone fracture and using method thereof
CN101653572B (en) Traditional Chinese medicine coloclysis composition for effectively treating pelvic inflammatory disease
CN106177817A (en) A kind of external used medicine treating acute soft tissue injury and preparation method thereof
CN106138415A (en) A kind of Chinese medicine composition of the femur head necrosis caused for a variety of causes
CN105362786A (en) Traditional Chinese medicine capsules for treating gall-stone and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20160511

RJ01 Rejection of invention patent application after publication