CN105560245A - 治疗呼吸道病症或疾病的化合物 - Google Patents

治疗呼吸道病症或疾病的化合物 Download PDF

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Publication number
CN105560245A
CN105560245A CN201510982692.9A CN201510982692A CN105560245A CN 105560245 A CN105560245 A CN 105560245A CN 201510982692 A CN201510982692 A CN 201510982692A CN 105560245 A CN105560245 A CN 105560245A
Authority
CN
China
Prior art keywords
ethyoxyl
pyridazin
piperidin
benzo
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510982692.9A
Other languages
English (en)
Chinese (zh)
Inventor
J·N·兰伯特
J·瑞恩
J·M·威尔逊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biota Scientific Management Pty Ltd
Original Assignee
Biota Scientific Management Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2010901601A external-priority patent/AU2010901601A0/en
Application filed by Biota Scientific Management Pty Ltd filed Critical Biota Scientific Management Pty Ltd
Publication of CN105560245A publication Critical patent/CN105560245A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/501Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CN201510982692.9A 2010-04-15 2011-04-14 治疗呼吸道病症或疾病的化合物 Pending CN105560245A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2010901601A AU2010901601A0 (en) 2010-04-15 Compound for the treatment of respiratory condition or disease
AU2010901601 2010-04-15
CN2011800192025A CN102844032A (zh) 2010-04-15 2011-04-14 治疗呼吸道病症或疾病的化合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2011800192025A Division CN102844032A (zh) 2010-04-15 2011-04-14 治疗呼吸道病症或疾病的化合物

Publications (1)

Publication Number Publication Date
CN105560245A true CN105560245A (zh) 2016-05-11

Family

ID=44788654

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2011800192025A Pending CN102844032A (zh) 2010-04-15 2011-04-14 治疗呼吸道病症或疾病的化合物
CN201510982692.9A Pending CN105560245A (zh) 2010-04-15 2011-04-14 治疗呼吸道病症或疾病的化合物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN2011800192025A Pending CN102844032A (zh) 2010-04-15 2011-04-14 治疗呼吸道病症或疾病的化合物

Country Status (16)

Country Link
US (1) US20110257192A1 (enExample)
EP (1) EP2558097B1 (enExample)
JP (1) JP6148618B2 (enExample)
KR (1) KR20130106267A (enExample)
CN (2) CN102844032A (enExample)
AU (1) AU2011241478B2 (enExample)
BR (1) BR112012026244A2 (enExample)
CA (1) CA2796207A1 (enExample)
EA (1) EA025224B1 (enExample)
ES (1) ES2647223T3 (enExample)
IL (1) IL222244A0 (enExample)
MX (1) MX2012011938A (enExample)
NZ (1) NZ603040A (enExample)
SG (2) SG10201502391WA (enExample)
WO (1) WO2011127538A1 (enExample)
ZA (1) ZA201207696B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR122020010204B1 (pt) 2013-04-12 2022-03-03 Obschestvo S Ogranichennoi Otvetstvennostiyu "Pharmenterprises" Composto derivado de glutarimida, seu uso, composiçâo farmacêutica e método de de preparação
KR20180038571A (ko) 2014-06-20 2018-04-16 아비라겐 테라퓨틱스, 인코포레이티드 [2-[1-(6-메틸-3-피리다지닐)-4-피페리디닐]에톡시]-3-에톡시-1,2-벤즈이속사졸의 무수 결정성 유리 염기 형태
US20240350487A1 (en) * 2023-03-13 2024-10-24 Altesa BioSciences, Inc. Method of dosing vapendavir to treat enterovirus infections

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009143571A1 (en) * 2008-05-27 2009-12-03 Biota Scientific Management Pty Ltd Antiviral salts
WO2010009288A1 (en) * 2008-07-17 2010-01-21 Schering Corporation Compositions and uses of antiviral active pharmaceutical agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR213700A0 (en) * 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
WO2003068222A1 (en) * 2002-02-14 2003-08-21 Viropharma Incorporated Methods of reducing rhinovirus contagion and related compositions
WO2004073710A1 (en) * 2003-02-21 2004-09-02 Apodemus Ab Treatment of diseases caused by ljungan virus by using pleconaril
US9308199B2 (en) * 2004-04-29 2016-04-12 Honeywell International Inc. Medicament formulations
US20060069124A1 (en) * 2004-09-07 2006-03-30 Rao P S Use of MDL-100,907 for treatment of allergic and eosinophil mediated diseases
AR057623A1 (es) * 2005-11-28 2007-12-05 Omega Bio Pharma H K Ltd Materiales y metodos para el tratamiento de las infecciones virales

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009143571A1 (en) * 2008-05-27 2009-12-03 Biota Scientific Management Pty Ltd Antiviral salts
WO2010009288A1 (en) * 2008-07-17 2010-01-21 Schering Corporation Compositions and uses of antiviral active pharmaceutical agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
P. MALLIA等: "Exacerbations of Asthma and Chronic Obstructive Pulmonary Disease(COPD): Focus on Virus Induced Exacerbations", 《CURRENT PHARMACEUTICAL DESIGN》 *

Also Published As

Publication number Publication date
IL222244A0 (en) 2012-12-31
JP6148618B2 (ja) 2017-06-14
ES2647223T3 (es) 2017-12-20
EP2558097A4 (en) 2013-09-11
MX2012011938A (es) 2013-01-28
EP2558097B1 (en) 2017-10-25
JP2013523844A (ja) 2013-06-17
WO2011127538A1 (en) 2011-10-20
AU2011241478A1 (en) 2012-11-01
SG10201502391WA (en) 2015-05-28
CA2796207A1 (en) 2011-10-20
ZA201207696B (en) 2014-03-26
EA201201416A1 (ru) 2013-03-29
KR20130106267A (ko) 2013-09-27
EP2558097A1 (en) 2013-02-20
CN102844032A (zh) 2012-12-26
US20110257192A1 (en) 2011-10-20
SG184430A1 (en) 2012-11-29
EA025224B1 (ru) 2016-12-30
AU2011241478B2 (en) 2016-12-01
BR112012026244A2 (pt) 2016-07-12
NZ603040A (en) 2015-03-27

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20160511

WD01 Invention patent application deemed withdrawn after publication