CN105541713B - 一种异喹啉化合物及其合成方法 - Google Patents
一种异喹啉化合物及其合成方法 Download PDFInfo
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- CN105541713B CN105541713B CN201610049500.3A CN201610049500A CN105541713B CN 105541713 B CN105541713 B CN 105541713B CN 201610049500 A CN201610049500 A CN 201610049500A CN 105541713 B CN105541713 B CN 105541713B
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- compound
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- isoquinoline
- arh
- chlorine
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- 0 C*C(C[C@@]1C=N*)=CC=C1C#Cc1ccc(*)cc1 Chemical compound C*C(C[C@@]1C=N*)=CC=C1C#Cc1ccc(*)cc1 0.000 description 2
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Description
Claims (5)
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CN201610049500.3A CN105541713B (zh) | 2016-01-26 | 2016-01-26 | 一种异喹啉化合物及其合成方法 |
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CN201610049500.3A CN105541713B (zh) | 2016-01-26 | 2016-01-26 | 一种异喹啉化合物及其合成方法 |
Publications (2)
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CN105541713A CN105541713A (zh) | 2016-05-04 |
CN105541713B true CN105541713B (zh) | 2018-04-06 |
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CN201610049500.3A Active CN105541713B (zh) | 2016-01-26 | 2016-01-26 | 一种异喹啉化合物及其合成方法 |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN109422724B (zh) * | 2017-08-29 | 2020-09-29 | 湖南科技大学 | 一种吲哚取代的异喹啉化合物及其合成方法 |
CN109678798B (zh) * | 2019-01-20 | 2023-01-17 | 湖南科技大学 | 一种异喹啉化合物的合成方法 |
CN110483481B (zh) * | 2019-09-18 | 2022-09-16 | 湖南科技大学 | 一种吲哚取代的二氢异喹啉化合物及其合成方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102009032548A1 (de) * | 2009-07-10 | 2011-02-10 | Icfs Gmbh | Verfahren zur Herstellung von Acetylendicarboxamidiniumsalzen(Bis-amidiniumsalzen der Acetylendicarbonsäure) |
CN103483255A (zh) * | 2012-06-13 | 2014-01-01 | 中国科学院上海有机化学研究所 | 氟代异喹啉类化合物及其制备方法 |
CN104478799A (zh) * | 2014-11-18 | 2015-04-01 | 上海交通大学 | 1,4-二烯丙基异喹啉的制备方法 |
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2016
- 2016-01-26 CN CN201610049500.3A patent/CN105541713B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102009032548A1 (de) * | 2009-07-10 | 2011-02-10 | Icfs Gmbh | Verfahren zur Herstellung von Acetylendicarboxamidiniumsalzen(Bis-amidiniumsalzen der Acetylendicarbonsäure) |
CN103483255A (zh) * | 2012-06-13 | 2014-01-01 | 中国科学院上海有机化学研究所 | 氟代异喹啉类化合物及其制备方法 |
CN104478799A (zh) * | 2014-11-18 | 2015-04-01 | 上海交通大学 | 1,4-二烯丙基异喹啉的制备方法 |
Non-Patent Citations (3)
Title |
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A room-temperature protocol to access isoquinolines through Ag(I) catalysed annulation of o-(1-alkynyl)arylaldehydes and ketones with NH4OAc: elaboration to berberine and palmatine;Virsinha Reddy,等;《Organic & Biomolecular Chemistry》;20150209(第13期);第3732-3741页 * |
An efficient synthesis of isoquinolines via rhodium-catalyzed direct C–H functionalization of arylhydrazines;Sai Zhang,等;《Organic &Biomolecular Chemistry》;20150618(第13期);第7920-7923页 * |
Indole as Neutral Leaving Group in Silver Nitrate Induced Cyclization Reactions of N-{2-[Alkynyl(hetero)aryl]methylene}indolin-1-amines for the Synthesis of Annulated Pyridine Derivatives;Nugzar Ghavtadze,等;《Eur. J. Org. Chem.》;20100210;第2010卷;第1787-1797页 * |
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CN105541713A (zh) | 2016-05-04 |
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