CN105535824A - Traditional Chinese medicine for treating acute pancreatitis - Google Patents

Traditional Chinese medicine for treating acute pancreatitis Download PDF

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Publication number
CN105535824A
CN105535824A CN201511012822.2A CN201511012822A CN105535824A CN 105535824 A CN105535824 A CN 105535824A CN 201511012822 A CN201511012822 A CN 201511012822A CN 105535824 A CN105535824 A CN 105535824A
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CN
China
Prior art keywords
parts
chinese medicine
traditional chinese
acute pancreatitis
radix
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Pending
Application number
CN201511012822.2A
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Chinese (zh)
Inventor
王璐
许璟
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Qingdao Changanda Pharmaceutical Co Ltd
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Qingdao Changanda Pharmaceutical Co Ltd
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Priority to CN201511012822.2A priority Critical patent/CN105535824A/en
Publication of CN105535824A publication Critical patent/CN105535824A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger

Abstract

The invention discloses a traditional Chinese medicine for treating acute pancreatitis. The traditional Chinese medicine for treating the acute pancreatitis is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 31-46 parts of vine of multiflower knotweed, 25-37 parts of flos daturae, 21-35 parts of dioscorea nipponica makino, 16-28 parts of lagotis clarkei, 13-20 parts of cudrania cochinchinensis, 11-18 parts of philippine flemingia root, 9-17 parts of false chinese swertia herb, 3-12 parts of radix curcumae and 4-10 parts of red peony root. The traditional Chinese medicine disclosed by the invention has the effects of strengthening spleen and tonifying lung, soothing the liver and relieving depression, promoting blood circulation to remove blood stasis as well as clearing away heat and drying dampness, has obvious treatment effect on the acute pancreatitis and is reliable in effect, and the components of the traditional Chinese medicine disclosed by the invention are wide in medicinal herb resource, easy to prepare and have no toxic or side effect. The traditional Chinese medicine prepared according to the invention can be used for safely and effectively healing the acute pancreatitis.

Description

A kind of Chinese medicine for the treatment of acute pancreatitis
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of acute pancreatitis.
Background technology
Acute pancreatitis is the pathophysiological process of the complexity participated in by many factors, not only separate but also interpenetrate between each factor, developing of common promotion disease, general multiple organ cell can be caused extensively impaired, antiotasis and permeability are had an impact, cause blood circulation obstacle, there is shock and systemic inflammatory response syndrome, multiple organ dysfunction syndrome, Severe Acute Pancreatitis SAP morbidity is anxious, and progress is fast, clinical manifestation is dangerous, its mortality rate can up to 40%, and complication is many, is the acute abdomen that a kind of case fatality rate is higher.
Find that pancreatitis should be treated in time, Chinese medicine conditioning and treating is best auxiliary treatment way, greatly can improve pancreatitic cure rate and shorten recovery time.The Chinese medicine preparation of current treatment acute pancreatitis based under rushing down, regulate the flow of vital energy, heat clearing away, to invigorate blood circulation, applying maximum is Radix Et Rhizoma Rhei, and applying frequency reaches more than 90%, is secondly Natrii Sulfas, Radix Bupleuri, Cortex Magnoliae Officinalis etc.Conventional prescription is: Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, Fructus Gardeniae, Fructus Aurantii Immaturus, Radix Aucklandiae (Radix Vladimiriae), Radix Et Rhizoma Rhei, Matrii Sulfas Exsiccatus etc.Food stagnation person separately adds lenitive pill; Acupuncture and ear acupuncture also can reach analgesic effect.But the Chinese medicine preparation prescription for the treatment of acute pancreatitis is numerous and jumbled at present, and great majority can not effect a permanent cure after taking, and relapse rate is high, limit the application of its further genralrlization.
Summary of the invention
Technical problem to be solved by this invention is: provide a kind of cure rate high and the acute pancreatitis Chinese medicine formula do not recurred.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
A kind of Chinese medicine for the treatment of acute pancreatitis provided by the invention, be made up of the raw material of Chinese medicine of following weight portion: Caulis Polygoni Multiflori 31-46 part, Flos Daturae 25-37 part, Rhizoma Dioscoreae Nipponicae 21-35 part, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 16-28 part, Radix Cudraniae 13-20 part, Radix Flemingiae Philippinensis 11-18 part, when medicine 9-17 part, Radix Curcumae 3-12 part, Radix Paeoniae Rubra 4-10 part.
Preferably, Chinese medicine provided by the invention is made up of the raw material of Chinese medicine of following weight portion: Caulis Polygoni Multiflori 39 parts, Flos Daturae 32 parts, Rhizoma Dioscoreae Nipponicae 30 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 21 parts, Radix Cudraniae 16 parts, Radix Flemingiae Philippinensis 14 parts, when medicine 14 parts, and Radix Curcumae 6 parts, Radix Paeoniae Rubra 8 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
One, general data:
This application in TCM in clinical observation case 100 example, wherein man 45 example, female 55 example, age 18-69 year.The shortest person's two weeks of the course of disease, most elder reaches half a year.
Two, diagnostic criteria:
1, lab testing: (1) pancreatin measures: serum amyloid enzyme values obviously raises >500U/dl.Comprise leukocyte to increase, hyperglycemia, abnormal liver function, low blood calcium, blood gas analysis and DIC Indexes Abnormality etc.
2, irradiation image diagnosis: (1) C-XF: inferior lobe of left lung is not opened, left half diaphram raises, and left side hydrothorax etc. reflect around diaphram and retroperitoneal inflammation.(2) plain abdominal radiograph: duodenum is inflated, represents the expansion of nearly section jejunum paralysis.Be also shown in colon abrupt sign, represent the expansion of transverse colon paralysis, splenic flexure colon and section colonic far away, without gas shadow, maybe can see cholelithiasis shadow and pancreatic stones shadow, and the disappearance of psoas major shadow etc.(3) Abdominal B type ultrasonography: can assisted diagnosis, B ultrasonic scanning can find gathering of pancreas edema and pancreas week liquid.(4) Enhanced CT: the change of pancreas comprises diffusivity or focal pancreas increases.Edema, downright bad liquefaction, pancreas surrounding tissue fogs, and thickens, and visible hydrops.
Three, usage and dosage:
Usage and dosage: medicinal warm water soaking in above-mentioned, after 10 minutes, is simmered in water after boiling with high heat 30 minutes again, taking liquid 150 milliliters, then add water and two to decoct, filter after twice medicinal liquid mixing, take at twice.Twice daily, one after each meal.
The course for the treatment of: 15 days be a course for the treatment of, the 2-5 course for the treatment of need be taken.
Four, criterion of therapeutical effect:
(1) cure: clinical cardinal symptom and sign disappear, and inflammation is pass on well slightly;
(2) effective: clinical cardinal symptom disappears, and minor symptom disappears substantially, inflammation takes a turn for the better;
(3) effective: cardinal symptom obviously alleviates, and inflammation alleviates to some extent;
(4) invalid; Cardinal symptom is unchanged, does not also worsen.
Five, therapeutic effect:
In clinical observation case, take medicine 10-60 days, cures 85 examples, effective 9 examples, effective 2 examples, invalid 2 examples.There is not other side effect in treatments period.
Beneficial effect of the present invention:
Chinese medicine of the present invention has effect of spleen invigorating lung benefiting, soothing liver-QI for relieving depression, blood circulation promoting and blood stasis dispelling, heat clearing and damp drying, and its treatment acute pancreatitis is evident in efficacy, reliable effect, and its component medicine source is wide, it is easy to prepare, have no side effect.The medicine that the present invention obtains can safe and effective healing acute pancreatitis.
Detailed description of the invention
Embodiment 1
A kind of Chinese medicine for the treatment of acute pancreatitis that the present embodiment provides, is made up of the raw material of Chinese medicine of following weight portion: Caulis Polygoni Multiflori 39 parts, Flos Daturae 32 parts, Rhizoma Dioscoreae Nipponicae 30 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 21 parts, Radix Cudraniae 16 parts, Radix Flemingiae Philippinensis 14 parts, when medicine 14 parts, and Radix Curcumae 6 parts, Radix Paeoniae Rubra 8 parts.
Model case:
Case 1:
Print certain, man, 46 years old, after eating and drinking too much at one meal, there is upper abdominal pain, and with nauseating sense, have heating paresthesia, be diagnosed as acute pancreatitis.Take the medicament 10 days of Chinese drug preparation of the present invention, symptom disappears substantially, occasionally has stomachache; Continue to strengthen 5 days, all symptoms all disappear, and cure.
Case 2:
Money, 40 years old, there is upper abdomen dull pain, abdominal distention in man, heating after excessive drinking.Be diagnosed as acute pancreatitis, take the medicament 2 days of Chinese drug preparation of the present invention, stomachache, abdominal distention slightly alleviate, and no longer vomit, health no longer generates heat, and continuously take 10 days, and symptom is humorous to be removed, recovery from illness.
Case 3:
Zhang, man, 59 years old, there is stomachache, abdominal distention in diaphragm of drinking, and with vomiting, feels sick, having heating paresthesia, through having a medical check-up, being diagnosed as acute pancreatitis.Take medicament prepared by Chinese medicine composition of the present invention, after 5 days, symptom disappears substantially, occasionally has stomachache; Stop antibiotic therapy, continue to strengthen and take medicament 9 days prepared by Chinese medicine composition of the present invention, all symptoms all disappear, and cure.

Claims (2)

1. treat the Chinese medicine of acute pancreatitis for one kind, it is characterized in that, be made up of the raw material of Chinese medicine of following weight portion: Caulis Polygoni Multiflori 31-46 part, Flos Daturae 25-37 part, Rhizoma Dioscoreae Nipponicae 21-35 part, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 16-28 part, Radix Cudraniae 13-20 part, Radix Flemingiae Philippinensis 11-18 part, when medicine 9-17 part, Radix Curcumae 3-12 part, Radix Paeoniae Rubra 4-10 part.
2. Chinese medicine according to claim 1, is characterized in that, is made up of the raw material of Chinese medicine of following weight portion: Caulis Polygoni Multiflori 39 parts, Flos Daturae 32 parts, Rhizoma Dioscoreae Nipponicae 30 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 21 parts, Radix Cudraniae 16 parts, Radix Flemingiae Philippinensis 14 parts, when medicine 14 parts, and Radix Curcumae 6 parts, Radix Paeoniae Rubra 8 parts.
CN201511012822.2A 2015-12-31 2015-12-31 Traditional Chinese medicine for treating acute pancreatitis Pending CN105535824A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201511012822.2A CN105535824A (en) 2015-12-31 2015-12-31 Traditional Chinese medicine for treating acute pancreatitis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201511012822.2A CN105535824A (en) 2015-12-31 2015-12-31 Traditional Chinese medicine for treating acute pancreatitis

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CN105535824A true CN105535824A (en) 2016-05-04

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432469A (en) * 2013-07-31 2013-12-11 刘海珍 Traditional Chinese medicine composition for treating acute pancreatitis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432469A (en) * 2013-07-31 2013-12-11 刘海珍 Traditional Chinese medicine composition for treating acute pancreatitis

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Application publication date: 20160504