CN103007189B - Chinese medicinal composition for treating acute pancreatitis - Google Patents
Chinese medicinal composition for treating acute pancreatitis Download PDFInfo
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Abstract
The invention relates to a Chinese medicinal composition for treating acute pancreatitis, which consists of the following Chinese medicinal raw materials in parts by weight: 10 to 30 parts of astragalus, 10 to 30 parts of codonopsis pilosula, 10 to 30 parts of roasted bighead atractylodes rhizome, 20 to 40 parts of coix seed, 10 to 30 parts of white peony root, 10 to 30 parts of red peony root, 10 to 20 parts of radix bupleuri, 10 to 20 parts of fructus amomi, 10 to 20 parts of herba lycopi, 10 to 20 parts of gizzard-membrane, 10 to 20 parts of radix curcumae, 5 to 15 parts of immature bitter orange, 5 to 15 parts of liquorice, 10 to 20 parts of abrus cantoniensis hance, and 10 to 20 parts of sedum sarmentosum. The Chinese medicinal composition has the functions of strengthening spleen and tonifying lung, soothing liver-qi stagnation, activating blood and removing stasis, and clearing heat and drying dampness, has the advantages of remarkable curative effect and reliable effect in treating acute pancreatitis, is wide in medicinal component source and easy to prepare, and does not have toxic or side effect.
Description
Technical field
The present invention relates to a kind of medicinal preparation of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of acute pancreatitis.
Background technology
Acute pancreatitis is after Different types of etiopathogenises causes pancreatin to be activated in pancreas, to cause pancreatic tissue autodigestion, edema, hemorrhage even downright bad inflammatory reaction.Clinical taking acute upper abdominal pain, feel sick, vomiting, heating and blood pancreatin increase etc. as feature.While there is acute pancreatitis, be easy to concurrent pancreas antibacterial and infect.Treatment is taking antibiotic antiinflammatory as main clinically, and its conventional antibiosis have the intravenous drips such as ampicillin, gentamycin, cephalosporin, metronidazole.There is the deficiency of weak curative effect.
The traditional Chinese medical science thinks, the main cause that causes acute pancreatitis is: eating cold and uncooked food excessively, greasy delicious food, pure wine savoury, cause spleen injury; Or feelings will do not relax, stagnation of QI due to depression of the liver, long-pending, the ascarid of gallbladder pancreatolith harasses, block Tianjin and manages in addition, causes liver and gall stasis, perverse and unreasonable manner taste; Or because of pathogenic heat, pyretic toxicity, many evil invasion and attack such as damp and hot, cause the disorder of middle part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels function, cause acute pancreatitis.
According to theory of Chinese medical science, for the pathogeny of acute pancreatitis, to dredge, flatulence, the dredging stasis of blood are solidifying, vigorate qi and replenish the blood is as Therapeutic Principle, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind ofly prepare conveniently, medicine source is wide, cost is low, the Chinese medicine composition of evident in efficacy, reliable effect, the treatment acute pancreatitis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of acute pancreatitis, it is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: Radix Astragali 10-30 part, Radix Codonopsis 10-30 part, Rhizoma Atractylodis Macrocephalae (parched) 10-30 part, Semen Coicis 20-40 part, Radix Paeoniae Alba 10-30 part, Radix Paeoniae Rubra 10-30 part, Radix Bupleuri 10-20 part, Fructus Amomi 10-20 part, Herba Lycopi 10-20 part, Endothelium corneum 10-20 part, Radix Curcumae 10-20 part, Fructus Aurantii Immaturus 5-15 part, Radix Glycyrrhizae 5-15 part, Herba Abri 10-20 part, Herba Sedi 10-20 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of acute pancreatitis, is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: 20 parts of the Radixs Astragali, 20 parts of Radix Codonopsis, 20 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Semen Coiciss, 20 parts of the Radix Paeoniae Albas, 20 parts of Radix Paeoniae Rubra, 15 parts of Radix Bupleuri, 15 parts of Fructus Amomis, 15 parts of Herba Lycopi, 15 parts of Endothelium corneum, 15 parts of Radix Curcumaes, 10 parts of Fructus Aurantii Immaturuss, 10 parts, Radix Glycyrrhizae, 15 parts of Herba Abris, 15 parts of Herba Sedis.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: the Radix Astragali has that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating are admittedly de-, wind dispelling is transported malicious effect; Radix Codonopsis has effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting; Rhizoma Atractylodis Macrocephalae (parched) has effect of dampness row water, QI invigorating, strengthening the spleen and stomach; Semen Coicis has that inducing diuresis to remove edema, spleen invigorating dry, effect of arthralgia relieving by relaxing muscles and tendons; The Radix Paeoniae Alba has effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Radix Paeoniae Rubra has effect of clearing away heat and cooling blood, eliminating stasis to stop pain; Radix Bupleuri have evacuate bring down a fever, effect of yang invigorating soothing liver-QI; Fructus Amomi has removing dampness appetizing, warming spleen and stopping diarrha, the antiabortive effect of regulating the flow of vital energy; Herba Lycopi has effect of blood circulation promoting and blood stasis dispelling, line water detumescence; Endothelium corneum has effect of promoting digestion and invigorating the stomach, eliminate indigestion calculus, astringency inducing reducing urination, arresting seminal emission; Radix Curcumae has effect of regulating qi to disperse stagnation, heart fire-clearing upset-relieving; Fructus Aurantii Immaturus has effect of the loose painful abdominal mass of reducing phlegm, dispelling the stagnated QI removing food stagnancy; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription; Herba Abri has effect of clearing away heat-damp and promoting diuresis, eliminating stasis to stop pain; Herba Sedi has effect of eliminating damp-heat, removing toxic substances.Drug component in the present composition is through dialectical compatibility, complements each other using, and has synergism, plays altogether effect of spleen invigorating lung benefiting, soothing liver-QI for relieving depression, blood circulation promoting and blood stasis dispelling, heat clearing and damp drying, acute pancreatitis reached to the object for the treatment of both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, does not occur toxic and side effects, total effective rate 94%, cure rate reaches 64%.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for acute pancreatitis, its raw material of Chinese medicine by following weight proportion forms: Radix Astragali 20g, Radix Codonopsis 20g, Rhizoma Atractylodis Macrocephalae (parched) 20g, Semen Coicis 30g, Radix Paeoniae Alba 20g, Radix Paeoniae Rubra 20g, Radix Bupleuri 15g, Fructus Amomi 15g, Herba Lycopi 15g, Endothelium corneum 15g, Radix Curcumae 15g, Fructus Aurantii Immaturus 10g, Radix Glycyrrhizae 10g, Herba Abri 15g, Herba Sedi 15g.
Embodiment 2
Treat a Chinese medicine composition for acute pancreatitis, its raw material of Chinese medicine by following weight proportion forms: Radix Astragali 10g, Radix Codonopsis 30g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Semen Coicis 40g, Radix Paeoniae Alba 10g, Radix Paeoniae Rubra 30g, Radix Bupleuri 10g, Fructus Amomi 20g, Herba Lycopi 10g, Endothelium corneum 20g, Radix Curcumae 10g, Fructus Aurantii Immaturus 15g, Radix Glycyrrhizae 5g, Herba Abri 20g, Herba Sedi 10g.
Embodiment 3
Treat a Chinese medicine composition for acute pancreatitis, its raw material of Chinese medicine by following weight proportion forms: Radix Astragali 30g, Radix Codonopsis 10g, Rhizoma Atractylodis Macrocephalae (parched) 30g, Semen Coicis 20g, Radix Paeoniae Alba 30g, Radix Paeoniae Rubra 10g, Radix Bupleuri 20g, Fructus Amomi 10g, Herba Lycopi 20g, Endothelium corneum 10g, Radix Curcumae 20g, Fructus Aurantii Immaturus 5g, Radix Glycyrrhizae 15g, Herba Abri 10g, Herba Sedi 20g.
Embodiment 4
Treat a Chinese medicine composition for acute pancreatitis, its raw material of Chinese medicine by following weight proportion forms: Radix Astragali 15g, Radix Codonopsis 25g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Semen Coicis 35g, Radix Paeoniae Alba 15g, Radix Paeoniae Rubra 25g, Radix Bupleuri 12g, Fructus Amomi 18g, Herba Lycopi 13g, Endothelium corneum 17g, Radix Curcumae 12g, Fructus Aurantii Immaturus 13g, Radix Glycyrrhizae 7g, Herba Abri 18g, Herba Sedi 12g.
Embodiment 5
Treat a Chinese medicine composition for acute pancreatitis, its raw material of Chinese medicine by following weight proportion forms: Radix Astragali 25g, Radix Codonopsis 15g, Rhizoma Atractylodis Macrocephalae (parched) 25g, Semen Coicis 25g, Radix Paeoniae Alba 25g, Radix Paeoniae Rubra 15g, Radix Bupleuri 18g, Fructus Amomi 12g, Herba Lycopi 18g, Endothelium corneum 12g, Radix Curcumae 18g, Fructus Aurantii Immaturus 7g, Radix Glycyrrhizae 13g, Herba Abri 12g, Herba Sedi 18g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soak 15～20 minutes, then add water and do not have approximately 8 centimetres of powder, decoct.At a simmer, adopt intense fire to decoct, after boiling, use slow fire boiling 20～30 minutes; Second decocts, and after water boils, decocts 15～20 minutes.Twice decoction extracting juice that removes slag, merges.
Treat a Chinese medicine composition for acute pancreatitis, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied to clinical observation case 50 examples, wherein male 24 examples, female's 26 examples, 30～68 years old age.The shortest person's two weeks of the course of disease, elder reaches half a year.
Two, diagnostic criteria:
1, lab testing: (1) pancreatin is measured: the serum amylase value >500U/dl that obviously raises.Comprise leucocytosis, hyperglycemia, abnormal liver function, low blood calcium, blood gas analysis and DIC Indexes Abnormality etc.;
2, irradiation image is learned diagnosis: (1) C-XF: inferior lobe of left lung is not opened, and left half diaphram raises, and left side hydrothorax etc. reflect diaphram around and retroperitoneal inflammation.。(2) plain abdominal radiograph: duodenum inflation, represents the expansion of nearly section jejunum paralysis.Be also shown in colon abrupt sign, represent the expansion of transverse colon paralysis, splenic flexure colon and section colonic far away are without gas shadow.Maybe can see cholelithiasis shadow and pancreatic stones shadow, and the disappearance of psoas major shadow etc.(3) Abdominal B type ultrasonography: can assisted diagnosis.B ultrasonic scanning can be found gathering of pancreas edema and pancreas week liquid.(4) Enhanced CT: the change of pancreas comprises that diffusivity or focal pancreas increase.Edema, downright bad liquefaction, pancreas surrounding tissue fogs, and thickens.And visible hydrops.
Three, usage and dosage: when clinical practice, component, consumption in compositions are taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.One day potion, the about 300ml of twice extracting juice of decocting, point early, late twice half an hour ante cibum warm taking.
Four, criterion of therapeutical effect:
(1) cure: clinical cardinal symptom and sign disappear, and inflammation is pass on well slightly;
(2) effective: clinical cardinal symptom disappears, and minor symptom disappears substantially, inflammation takes a turn for the better;
(3) effective: cardinal symptom obviously alleviates, and inflammation alleviates to some extent;
(4) invalid; Cardinal symptom is unchanged, does not also worsen.
Five, therapeutic effect: in this clinical observation case, the 1-10 days that takes medicine, cures 32 examples, effective 11 examples, effective 4 examples, invalid 3 examples.During treatment, there is not toxic and side effects.
Six, model case:
Case 1:
Connect certain, man, 44 years old, after eating and drinking too much at one meal, there is upper abdominal pain, and with feel sick sense, have heating paresthesia, be diagnosed as acute pancreatitis.Take medicament 3 days prepared by Chinese medicine composition of the present invention, symptom disappears substantially, occasionally has stomachache; Continue to strengthen 3 days, all symptoms all disappear, and cure.
Case 2:
Song, man, 48 years old, after excessive drinking, there is upper abdomen dull pain, abdominal distention, not hungry and vomit, heating.Be diagnosed as acute pancreatitis.Take medicament 2 days prepared by Chinese medicine composition of the present invention, stomachache, abdominal distention slightly alleviate, no longer vomiting, and health no longer generates heat, and continuously takes 3 days, and symptom is humorous to be removed, recovery from illness.
Claims (1)
1. a Chinese medicine composition for the treatment of acute pancreatitis, is characterized in that: its raw material of Chinese medicine by following weight proportion forms: Radix Astragali 20g, Radix Codonopsis 20g, Rhizoma Atractylodis Macrocephalae (parched) 20g, Semen Coicis 30g, Radix Paeoniae Alba 20g, Radix Paeoniae Rubra 20g, Radix Bupleuri 15g, Fructus Amomi 15g, Herba Lycopi 15g, Endothelium corneum 15g, Radix Curcumae 15g, Fructus Aurantii Immaturus 10g, Radix Glycyrrhizae 10g, Herba Abri 15g, Herba Sedi 15g.
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| CN104398575A (en) * | 2014-12-27 | 2015-03-11 | 张冬 | Traditional Chinese medicine composition for treating acute pancreatitis and preparation method thereof |
| CN104524514A (en) * | 2014-12-27 | 2015-04-22 | 张冬 | Traditional Chinese medicine decoction for treating acute pancreatitis and preparation method of traditional Chinese medicine decoction |
| CN104398835A (en) * | 2014-12-27 | 2015-03-11 | 宋晓华 | Traditional Chinese medicine for treating acute pancreatitis and preparation method thereof |
| CN104398906A (en) * | 2014-12-27 | 2015-03-11 | 赵红 | Traditional Chinese medicine preparation for treating acute pancreatitis and preparation method thereof |
| CN104491477A (en) * | 2015-01-12 | 2015-04-08 | 白忠可 | Traditional Chinese medicine for treating pancreatitis and preparation method thereof |
| CN105412489A (en) * | 2015-12-31 | 2016-03-23 | 青岛昌安达药业有限公司 | Traditional Chinese medicine preparation for treating acute pancreatitis |
| CN105596962A (en) * | 2016-02-19 | 2016-05-25 | 梁黎明 | Traditional Chinese medicine composition for treating acute pancreatitis |
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|---|---|
| CN103007189A (en) | 2013-04-03 |
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