CN105535684A - Traditional Chinese medicine preparation for treating acne rosacea - Google Patents

Traditional Chinese medicine preparation for treating acne rosacea Download PDF

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Publication number
CN105535684A
CN105535684A CN201610042705.9A CN201610042705A CN105535684A CN 105535684 A CN105535684 A CN 105535684A CN 201610042705 A CN201610042705 A CN 201610042705A CN 105535684 A CN105535684 A CN 105535684A
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chinese medicine
medicine preparation
acne rosacea
preparation
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CN201610042705.9A
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李王贻
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/28Mercury; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/36Arsenic; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532Agastache, e.g. giant hyssop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Abstract

The invention relates to a traditional Chinese medicine preparation for treating acne rosacea. The traditional Chinese medicine preparation comprises an external preparation and an internal preparation, wherein the external preparation is prepared by grinding the following medicine materials in parts by weight into fine powder: 2.5-4 parts of Sichuan Coptis chinensis, 2.5-4 parts of golden cypress, 2.5-4 parts of Acacia catechu, 2.5-4 parts of indigo naturalis, 2.5-4 parts of clam meal, 2.5-4 parts of calcined gypsum, 1.8-2.2 parts of realgar, 1.8-2.2 parts of calomel, 1.8-2.2 parts of dragon's blood, 1-2 parts of dried alum, 1-2 parts of borneol, 0.2-0.4 part of musk and 15-25 wintersweet flowers (dried); each dosage of the internal preparation consists of the following medicinal materials in parts by weight: 9-12 parts of loquat leaves, 9-12 parts of radices trichosanthis, 9-12 parts of white mulberry root-barks, 6-8 parts of rhizoma atractylodis, 6-8 parts of scutellaria baicalensis, 28-34 parts of semen coicis and 2-3 parts of liquorice. Compared with the prior art, the traditional Chinese medicine preparation is used both internally and externally, can treat both symptoms and root causes, and is scientific in formula, and definite in treatment effect on lung and stomach risen accumulated heat and subcutaneous stasis type acne rosacea.

Description

A kind of Chinese medicine preparation for the treatment of acne rosacea
Technical field
The present invention relates to Chinese traditional medicine, be specifically related to a kind of Chinese medicine preparation for the treatment of acne rosacea.
Background technology
Acne rosacea is also known as rosacea or acne rosacea, and the cause of disease is still not fully aware of.May be on the basis of seborrhea, due to the effect of the various injurious factor in inside and outside, make affected part vasomotor nerve functional disorder, caused by blood capillary permanent enlargement.Demodex folliculorum and local repeated infection are morbidity key factors.Be addicted to drink, smoking, irritative food, digestive tract function are disorderly, endocrine function imbalance (especially menopause), Nervous and Mental Factors, focal infection, long term all can bring out in cold and hot factor such as hot operation, Exposure to Sunlight, cold, the wind etc. of skin and increase the weight of primary disease.Be apt to occur in the middle part of face, based on nose, the wing of nose, be secondly buccal, chin portion, forehead, often symmetrical, be mainly in middle age, women is more, and the how concurrent seborrhea of patient, face is just as fat liquoring.Skin lesion shows as erythema, telangiectasis and has the hair follicle pimple and pustule etc. of inflammation.The course of disease is slow, can be divided into for three phases: erythema phase, pimple phase, loose phase.At present due to etiology unknown, treatment mostly is conservative treatment as with Clindamycin Gel, benza gel, Fusidic Acid Cream, mupirocin ointment etc., also can select Metrogel, Tinidazole Gel, low concentration tretinoin preparation etc.Play bactericidal antiphlogistic, the object held back the development, do not reach the effect of effecting a permanent cure.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of acne rosacea, the technical scheme of employing is:
Said preparation comprises external preparation and oral preparations, described external preparation grinds to fine flour by the medical material of following weight portion: Rhizoma Coptidis, Cortex Phellodendri, catechu, Indigo Naturalis, Pulvis concha Mactrae, each 2.5-4 part of Gypsum Fibrosum Preparatum, Realgar, Calomelas, each 1.8-2.2 part of Sanguis Draxonis, the each 1-2 part of dried Alumen, Borneolum Syntheticum, Moschus 0.2-0.4 part, Flos Mume (drying) 15-25 piece; The every agent of described oral preparations is made up of the medical material of following weight portion: each 9-12 part of Folium Eriobotryae, Radix Trichosanthis, Cortex Mori, each 6-8 part of Rhizoma Atractylodis, Radix Scutellariae, Semen Coicis 28-34 part, Radix Glycyrrhizae 2-3 part.
9-12 part Radix Trichosanthis can also be replaced with the Herba Pogostemonis of 4-6 part.
Preferred version is that described external preparation grinds to fine flour by the medical material of following weight portion: Rhizoma Coptidis, Cortex Phellodendri, catechu, Indigo Naturalis, Pulvis concha Mactrae, each 3 parts of Gypsum Fibrosum Preparatum, Realgar, Calomelas, each 2 parts of Sanguis Draxonis, each 1.5 parts of dried Alumen, Borneolum Syntheticum, 0.3 part, Moschus, Flos Mume (drying) 20; Described oral preparations is made up of the medical material of following weight portion: each 10 parts of Folium Eriobotryae, Radix Trichosanthis, Cortex Mori, each 8 parts of Rhizoma Atractylodis, Radix Scutellariae, Semen Coicis 30 parts, 3 parts, Radix Glycyrrhizae.
Correspondingly, the weight portion of described Herba Pogostemonis is 5 parts.
Compared with prior art, all execute inside and outside the present invention, treating both the principal and secondary aspects of a disease, scientific formula, to the acne rosacea determined curative effect of steaming, space between skin and muscles stasis type on accumulated heat in the lung and stomach.
Detailed description of the invention
Embodiment 1, a kind of Chinese medicine preparation for the treatment of acne rosacea, comprise external preparation and oral preparations, described external preparation grinds to fine flour by the medical material of following weight portion: Rhizoma Coptidis, Cortex Phellodendri, catechu, Indigo Naturalis, Pulvis concha Mactrae, each 3g of Gypsum Fibrosum Preparatum, Realgar, Calomelas, each 2g of Sanguis Draxonis, the each 1.5g of dried Alumen, Borneolum Syntheticum, Moschus 0.3g, Flos Mume (drying) 20; The every agent of described oral preparations is made up of the medical material of following weight portion: each 10g of Folium Eriobotryae, Radix Trichosanthis, Cortex Mori, each 8g of Rhizoma Atractylodis, Radix Scutellariae, Semen Coicis 30g, Radix Glycyrrhizae 3g.
Song component in external preparation is ground into fine flour with Chinese medicine Universalpulverizer respectively, uses vial sealed storage, and the used time gets a little medicamental pulverata, adds appropriate cold water and is in harmonious proportion, smear affected part with duck feathers, and every day sooner or later respectively once.
Oral preparations decoction, the next day potion, sooner or later clothes.
Embodiment 2, as patient's cold syndrome of the stomach, the Herba Pogostemonis of available 5g replaces 10g Radix Trichosanthis.
Applicant once treated patient 5 example with the party, and equal pimple fades, tuberosity is little, and nasal cavity is dry and astringent to be subtracted, and red filament removes, and none recurrence.

Claims (4)

1. treat the Chinese medicine preparation of acne rosacea for one kind, comprise external preparation and oral preparations, it is characterized in that described external preparation grinds to fine flour by the medical material of following weight portion: Rhizoma Coptidis, Cortex Phellodendri, catechu, Indigo Naturalis, Pulvis concha Mactrae, each 2.5-4 part of Gypsum Fibrosum Preparatum, Realgar, Calomelas, each 1.8-2.2 part of Sanguis Draxonis, the each 1-2 part of dried Alumen, Borneolum Syntheticum, Moschus 0.2-0.4 part, Flos Mume (drying) 15-25 piece; The every agent of described oral preparations is made up of the medical material of following weight portion: each 9-12 part of Folium Eriobotryae, Radix Trichosanthis, Cortex Mori, each 6-8 part of Rhizoma Atractylodis, Radix Scutellariae, Semen Coicis 28-34 part, Radix Glycyrrhizae 2-3 part.
2. a kind of Chinese medicine preparation for the treatment of acne rosacea according to claim 1, is characterized in that replacing 9-12 part Radix Trichosanthis with the Herba Pogostemonis of 4-6 part.
3. a kind of Chinese medicine preparation for the treatment of acne rosacea according to claim 1, it is characterized in that described external preparation grinds to fine flour by the medical material of following weight portion: Rhizoma Coptidis, Cortex Phellodendri, catechu, Indigo Naturalis, Pulvis concha Mactrae, each 3 parts of Gypsum Fibrosum Preparatum, Realgar, Calomelas, each 2 parts of Sanguis Draxonis, each 1.5 parts of dried Alumen, Borneolum Syntheticum, 0.3 part, Moschus, Flos Mume (drying) 20; Described oral preparations is made up of the medical material of following weight portion: each 10 parts of Folium Eriobotryae, Radix Trichosanthis, Cortex Mori, each 8 parts of Rhizoma Atractylodis, Radix Scutellariae, Semen Coicis 30 parts, 3 parts, Radix Glycyrrhizae.
4. a kind of Chinese medicine preparation for the treatment of acne rosacea according to claim 2, is characterized in that the weight portion of described Herba Pogostemonis is 5 parts.
CN201610042705.9A 2016-01-22 2016-01-22 Traditional Chinese medicine preparation for treating acne rosacea Withdrawn CN105535684A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108671087A (en) * 2018-06-28 2018-10-19 成都中医药大学附属医院 A kind of pharmaceutical composition and its preparation method and application for treating brandy nose

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103893582A (en) * 2014-03-02 2014-07-02 马芳 Traditional Chinese medicament for treating acne rosacea
CN104415210A (en) * 2013-08-29 2015-03-18 杜淑卿 Ointment for treating rosacea
CN104415199A (en) * 2013-08-28 2015-03-18 崔旭 Sichuan rhizoma coptidis, rhizoma chuanxiong and Cortex phellodendron powder

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104415199A (en) * 2013-08-28 2015-03-18 崔旭 Sichuan rhizoma coptidis, rhizoma chuanxiong and Cortex phellodendron powder
CN104415210A (en) * 2013-08-29 2015-03-18 杜淑卿 Ointment for treating rosacea
CN103893582A (en) * 2014-03-02 2014-07-02 马芳 Traditional Chinese medicament for treating acne rosacea

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
陈金广等: "《中国医学现代临床研究荟萃》", 31 January 1994, 知识出版社出版 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108671087A (en) * 2018-06-28 2018-10-19 成都中医药大学附属医院 A kind of pharmaceutical composition and its preparation method and application for treating brandy nose

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Application publication date: 20160504