CN105535363A - Traditional Chinese medicine composition for treating cirrhosis - Google Patents
Traditional Chinese medicine composition for treating cirrhosis Download PDFInfo
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- CN105535363A CN105535363A CN201511012827.5A CN201511012827A CN105535363A CN 105535363 A CN105535363 A CN 105535363A CN 201511012827 A CN201511012827 A CN 201511012827A CN 105535363 A CN105535363 A CN 105535363A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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Abstract
The invention discloses a traditional Chinese medicine composition for treating cirrhosis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 30-45 parts of caulis polygoni multiflori, 21-34 parts of rhizoma dioscoreae nipponicae, 13-27 parts of flos daturae, 10-19 parts of radix cudramiae, 5-12 parts of herba lagotis, 3-11 parts of philippine flemingia root, 3-8 parts of radix paeoniae rubra and 2-7 parts of herba scutellariae barbatae. Compared with prior art, major advantages of the traditional Chinese medicine composition disclosed by the invention are as follows: the adopted genuine medicinal materials and pure Chinese herbal medicines do not cause any toxic or side effect and are in reasonable compatibility as monarch, minister, assistant and guide and interact and coordinate to hit the pathogenesis and play a remarkable role in cirrhosis treatment.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of liver cirrhosis.
Background technology
Liver cirrhosis, hepatic ascites one are diseases common in people's mouth, and the reason caused can be caused by many reasons, and mainly because the long-term damage livers such as hepatitis B, hepatitis C, fatty liver cause, liver is Progressive symmetric erythrokeratodermia, diffusivity, fibrous lesions.Liver cirrhosis clinical with liver function damage and portal hypertension for main manifestations.Think according to theory of Chinese medical science, liver QI and blood is retarded by silt, meridians are inaccessible, body fluid can not defeated cloth with nutrition liver, liver loses supports, therefore liver cirrhosis, Er Cheng Disorder knot, therefore occur: diet minimizings, indigestion, abdominal distention after meal, feel sick, mental weariness, become thin, irritability, insomnia, both sides of the chest distending pain, liver palm, jaundice, the phenomenon liver cirrhosis such as yellow urine be posthepatitic cirrhosis at China's great majority, small part is alcoholic cirrhosis and Cirrhosis In Schistosomiasis.Histopathology there are hepatic necrosis, the regeneration of remaining liver cell nodules, connective tissue proliferation and fiber widely every formation, cause lobules of liver structural deterioration and pseudolobuli formation, liver is out of shape gradually, hardening and develop into liver cirrhosis.In early days because liver compensation more by force can non-evident sympton, stage with liver function injury and portal hypertension for main manifestations, and have multisystem to get involved, often there is the complication such as upper gastrointestinal hemorrhage, hepatic encephalopathy, secondary infection, hypersplenism, ascites, canceration late period.At present, treatment liver cirrhosis does not have any specific drug, is substantially all from traditional Chinese medical science angle, multiplex dispersing the stagnated live-QI to relieve the stagnation of QI, heat clearing away poison, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, and clearing away heat-damp and promoting diuresis medicine takes Western medicine hepatitis virus resisting and hepatic treatment in addition.As adopted the antiviral treatments such as rummy regulation, Entecavir, ribavirin and interferon, use vitamin K 1 injection again, reduced glutathione, 5% glucose injection adds vitamin C, potassium chloride etc. and protects the liver, or Silybin Capsules for oral administration, anethol trithione etc. are with inflammation in liver and the promoting the function of the gallbladder to alleviate jaundice of disappearing, but it is undesirable that these treat its effect, cure slow, therapy of combining Chinese and Western medicine, often can receive good effect, but medical expense is higher.Liver cirrhosis has become one of modal disease having a strong impact on the healthy of people and quality of life, Therapeutic Principle clinically for liver cirrhosis early finds early treatment, the object work for the treatment of liver cirrhosis will be reached by comprehensive Therapeutic Method simultaneously, doctor trained in Western medicine is with hepatoprotective detoxicating over the years, mend albumen, tap the abdomen as optimal treatment rule, though short term effect is very optimistic, late result is unsatisfactory.
summary of the invention
Technical problem to be solved by this invention is: the Chinese medicine composition providing a kind of therapeutic effect, has no side effect, and rate is lower repeatedly.For solving the problems of the technologies described above, the technical solution used in the present invention is:
A kind of Chinese medicine composition for the treatment of liver cirrhosis provided by the invention, is made up of the raw material of Chinese medicine of following weight portion: Caulis Polygoni Multiflori 30-45 part, Rhizoma Dioscoreae Nipponicae 21-34 part, Flos Daturae 13-27 part, Radix Cudraniae 10-19 part, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 5-12 part, Radix Flemingiae Philippinensis 3-11 part, Radix Paeoniae Rubra 3-8 part, Herba Scutellariae Barbatae 2-7 part.
Preferably, Chinese medicine provided by the invention is made up of the raw material of Chinese medicine of following weight portion: Caulis Polygoni Multiflori 37 parts, Rhizoma Dioscoreae Nipponicae 28 parts, Flos Daturae 20 parts, Radix Cudraniae 13 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 9 parts, Radix Flemingiae Philippinensis 6 parts, Radix Paeoniae Rubra 5 parts, Herba Scutellariae Barbatae 4 parts.
Usage and dosage: medicinal warm water soaking in above-mentioned, after 10 minutes, is simmered in water after boiling with high heat 30 minutes again, taking liquid 150 milliliters, then add water and two to decoct, filter after twice medicinal liquid mixing, take at twice.Twice daily, one after each meal.
The course for the treatment of: 15 days be a course for the treatment of, the 2-5 course for the treatment of need be taken.
Beneficial effect of the present invention:
Compared with prior art, major advantage of the present invention is, what the present invention adopted is authentic medicinal herbs, adopts pure Chinese herbal medicine, does not have toxic and side effects, monarch, and compatibility is reasonable, and effect is coordinated mutually, and hit pathogenesis, the significant effect played in treatment liver cirrhosis.
Detailed description of the invention
Embodiment 1
A kind of Chinese medicine composition for the treatment of liver cirrhosis that the present embodiment provides, is made up of the raw material of Chinese medicine of following weight portion: Caulis Polygoni Multiflori 37 parts, Rhizoma Dioscoreae Nipponicae 28 parts, Flos Daturae 20 parts, Radix Cudraniae 13 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 9 parts, Radix Flemingiae Philippinensis 6 parts, Radix Paeoniae Rubra 5 parts, Herba Scutellariae Barbatae 4 parts.
Clinical laboratory data:
1, physical data: inventor have collected 200 routine liver cirrhosis patients between-2015 days in 2012 altogether, wherein, 25 years old-55 years old age, the state of an illness 0.5 year-2 years.
2, test method:
(1) be divided at random: treatment group 100 example, matched group 100 example.The data there was no significant differences such as two groups of ages, have comparability.
(2) the oral the present invention for the treatment of group is according to the Chinese medicine of specific embodiment 1, takes according to above-mentioned usage and dosage; Matched group takes Entecavir, takes to specifications, 2 months courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome:
3.1 criterions of therapeutical effect:
Recovery from illness: the clinical symptoms of liver cirrhosis all disappears.
Take a turn for the better: the clinical symptom relief of liver cirrhosis, the state of an illness is controlled.
Invalid: the clinical symptoms of liver cirrhosis is without being clearly better or increasing the weight of.With recovery from illness and the calculating effective percentage that takes a turn for the better.
3.2, statistical result is treated as follows:
Comparitive study
Experimental group: recovery from illness 87 example, take a turn for the better 10 examples, invalid 3 examples;
Matched group: recovery from illness 60 example, take a turn for the better 13 examples, invalid 27 examples;
To the return visit of above individuality of curing through 1 year, do not find the individuality recurred.This is visible, and the medicine adopting prescription of the present invention obtained can safe and effective treatment liver cirrhosis.
Model case:
Case 1: beam, female, 59 years old, patient feels stomach discomfort for the first time, thinks it is stomach-ache, by normal outbreak, through hospital diagnosis, this patient is early stage liver cirrhosis, after through taking the Chinese medicine of the embodiment of the present invention 1, after 1 course for the treatment of, muscle power is recovered gradually, and can work, continue to take 3 courses for the treatment of, through hospital diagnosis, Patients ' Hepatocytes blocks disappearance, liver function reaches normal person's level, does not recur.Case 2: Song, man, 58 years old, live extremely irregular, often excessive drinking causes hepatocyte to harden, and the Chinese medicine taking the embodiment of the present invention 1 is treated, after 1 course for the treatment of, conscious physical recovery is normal, and muscle power increases, and can work, continue to take 3 courses for the treatment of, through hospital diagnosis, patient's hepatocirrhosis symptoms disappears, liver function reaches normal person's level, does not recur.
Claims (2)
1. treat a Chinese medicine composition for liver cirrhosis, it is characterized in that, be made up of the raw material of Chinese medicine of following weight portion: Caulis Polygoni Multiflori 30-45 part, Rhizoma Dioscoreae Nipponicae 21-34 part, Flos Daturae 13-27 part, Radix Cudraniae 10-19 part, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 5-12 part, Radix Flemingiae Philippinensis 3-11 part, Radix Paeoniae Rubra 3-8 part, Herba Scutellariae Barbatae 2-7 part.
2. Chinese medicine composition according to claim 1, is characterized in that, is made up of the raw material of Chinese medicine of following weight portion: Caulis Polygoni Multiflori 37 parts, Rhizoma Dioscoreae Nipponicae 28 parts, Flos Daturae 20 parts, Radix Cudraniae 13 parts, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 9 parts, Radix Flemingiae Philippinensis 6 parts, Radix Paeoniae Rubra 5 parts, Herba Scutellariae Barbatae 4 parts.
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CN105126043A (en) * | 2015-10-27 | 2015-12-09 | 陈远征 | Traditional Chinese medicine composition for treating liver cirrhosis and application thereof |
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