CN105533170A - Use method of additive for preventing and treating heat stress syndromes of beef cattle - Google Patents
Use method of additive for preventing and treating heat stress syndromes of beef cattle Download PDFInfo
- Publication number
- CN105533170A CN105533170A CN201510923423.5A CN201510923423A CN105533170A CN 105533170 A CN105533170 A CN 105533170A CN 201510923423 A CN201510923423 A CN 201510923423A CN 105533170 A CN105533170 A CN 105533170A
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- China
- Prior art keywords
- beef cattle
- additive
- feed
- heat stress
- gaba
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- 241000283690 Bos taurus Species 0.000 title claims abstract description 53
- 235000015278 beef Nutrition 0.000 title claims abstract description 48
- 239000000654 additive Substances 0.000 title claims abstract description 26
- 230000000996 additive effect Effects 0.000 title claims abstract description 26
- 238000000034 method Methods 0.000 title claims abstract description 20
- 208000025599 Heat Stress disease Diseases 0.000 title claims abstract description 14
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 claims abstract description 31
- 229960003692 gamma aminobutyric acid Drugs 0.000 claims abstract description 24
- 230000008642 heat stress Effects 0.000 claims abstract description 16
- 239000013589 supplement Substances 0.000 claims abstract description 8
- 240000008042 Zea mays Species 0.000 claims abstract description 4
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims abstract description 4
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims abstract description 4
- 239000012141 concentrate Substances 0.000 claims abstract description 4
- 235000005822 corn Nutrition 0.000 claims abstract description 4
- 239000010902 straw Substances 0.000 claims abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 4
- 244000046052 Phaseolus vulgaris Species 0.000 claims description 3
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- OGNSCSPNOLGXSM-UHFFFAOYSA-N (+/-)-DABA Natural products NCCC(N)C(O)=O OGNSCSPNOLGXSM-UHFFFAOYSA-N 0.000 abstract description 7
- 230000036039 immunity Effects 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 5
- 239000000203 mixture Substances 0.000 abstract description 3
- 230000001737 promoting effect Effects 0.000 abstract description 3
- 230000007774 longterm Effects 0.000 abstract description 2
- 230000035790 physiological processes and functions Effects 0.000 abstract description 2
- 235000019764 Soybean Meal Nutrition 0.000 abstract 1
- 230000003450 growing effect Effects 0.000 abstract 1
- 230000017525 heat dissipation Effects 0.000 abstract 1
- 239000004455 soybean meal Substances 0.000 abstract 1
- 230000035882 stress Effects 0.000 description 7
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 235000021050 feed intake Nutrition 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 230000005855 radiation Effects 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000002124 endocrine Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 229960000890 hydrocortisone Drugs 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 1
- XUIIKFGFIJCVMT-GFCCVEGCSA-N D-thyroxine Chemical compound IC1=CC(C[C@@H](N)C(O)=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-GFCCVEGCSA-N 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 241000282849 Ruminantia Species 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000007969 cellular immunity Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003862 glucocorticoid Substances 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 229960003444 immunosuppressant agent Drugs 0.000 description 1
- 230000001861 immunosuppressant effect Effects 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000003836 peripheral circulation Effects 0.000 description 1
- 230000006461 physiological response Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000008646 thermal stress Effects 0.000 description 1
- 229940034208 thyroxine Drugs 0.000 description 1
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/02—Breeding vertebrates
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Environmental Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
Abstract
The invention discloses an additive for preventing and treating heat stress syndromes of beef cattle and a use method of the additive. The additive is medical gamma-aminobutyric acid (GABA). The method comprises the following steps of adding the medical GABA with the addition quantity of 0.5-4.5g/d to a feed for the beef cattle during a heat stress period, uniformly mixing the medical GABA and the feed so as to obtain a mixture, and feeding the beef cattle with the mixture, wherein a course of treatment includes 20 days, the beef cattle are fed for 3 courses of treatment namely 60 days in all, and the beef cattle can drink water freely. The feed for the beef cattle is a concentrate supplement feed prepared from corn, soybean meal and the like, or a coarse supplement feed prepared from pasturage, straw, vinasse and the like; the beef cattle are growing beef cattle and fattening beef cattle. According to the additive and the use method thereof disclosed by the invention, the medical GABA starts with maintaining the stable state of organisms and the healthy state of the organisms under extreme conditions, coordinates the physiological functions of the beef cattle, and improves the adaptability of the beef cattle to stressors, so that after the medical GABA is added for a long term, the effects of facilitating the enhancement of the immunity of the organisms, promoting multi-channel heat dissipation of the organisms, increasing the return rate of the feed, and promoting the maximum development of growing properties can be achieved.
Description
Technical field
The present invention relates to field of veterinary, specifically a kind of using method of the additive for preventing and treating beef cattle heat stress syndrome.
Background technology
Along with global warming, the harm of heat stress to human health and animal reproduction, raising more and more receives the concern of people; China's most area hot phase in summer reaches 3 months, and the hot and humid weather duration of the Changjiang river areas to the south is then longer, and High Temperature Disaster is the natural hazards risk that China East China takes place frequently; Beef cattle dispel the heat in high temperature difficulty, thermal balance imbalance cause heat stress, beef cattle feed intake decline, cause weightening finish decline, price of deed rate also reduces, and has a strong impact on household economy benefit; Simultaneously due to stress in glucocorticoid secretion increase, immunity of organisms is suppressed, and very easily bring out the popular of various typical case or atypical infectious disease, particularly some immunosuppressant disease M & Ms increase, and cause larger economic loss; Therefore, carry out heat stress harm and study and explore heat stress prevention and control measure there is important academic significance and economic worth, both at home and abroad in the research in fowl and animal thermal stress prevention and control direction, often, study the prevention and control effect of feed addictive to heat stress from single factor test intervention; Such as simple Chinese herbal medicine adds or the vitamin of diet nutrient formulation optimization or antioxidation adds with trace element; Although these researchs all achieve certain achievement, and develop some alternative products, but still there is larger room for promotion in the result of use of these products, and the cultivation of product spininess to pig and bird of anti-heat stress designs, almost not for the product that the physiological characteristic of ruminant especially beef cattle designs on market; In recent years, GABA (γ-Aminobutyricacid, GABA) carries out anti-heat stress research and achieves good experiment effect in pig and chicken body, but not yet finds with beef cattle to be at present the correlative study of experimental subjects.
Summary of the invention
The object of the present invention is to provide a kind of safe and reliable, the using method that effectively can prevent and treat the green safety medicine of beef cattle heat stress and other syndromes, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
A kind of additive for preventing and treating beef cattle heat stress syndrome and using method thereof, described additive is medicinal GABA, described method is: in the feed of the beef cattle of heat stress phase, add medicinal GABA, addition is 0.5 ~ 4.5g/d, feed after medicinal GABA is mixed with feed, within 20 days, be a course for the treatment of, feed altogether 60 days 3 courses for the treatment of, freely drink water.
As the further scheme of the present invention: described cattle feed adopts the concentrate supplement coordinated by corn, dregs of beans etc.
As the present invention's further scheme: described cattle feed adopts the coarse fodders such as herbage, straw, vinasse to supplement material.
As the present invention's further scheme: described beef cattle is made a living and puts on flesh ox and fatten beef cattle.
Compared with prior art, the invention has the beneficial effects as follows: the problem that the present invention solves studies GABA by experiment to the impact of beef cattle resisting stress performance and the optimum amount establishing beef ox fattening phase GABA, start with from aspects such as adjustment immunity of organism, production performance and heat radiations, focus on the drug mechanism of the aspect further investigation anti-heat stress such as the heat radiation of cellular immunity, mucosal immunity, specific immunity and peripheral circulation, respiratory tract evaporative heat loss, excretion heat radiation; In the present invention, GABA starts with from maintenance body stable state under extreme conditions, body health state, coordinate the physiological function of beef cattle, improve beef cattle to the adaptability of stressor, long-term interpolation is not only favourable to adjustment immunity of organism simultaneously, can also promote that body dispels the heat by all kinds of means, improve the maximum performance of price of deed rate, growth promoting effects performance.
Detailed description of the invention
Be described in more detail below in conjunction with the technical scheme of detailed description of the invention to this patent.
Embodiment 1
A kind of additive for preventing and treating beef cattle heat stress syndrome and using method thereof, described additive is medicinal GABA, described method is: in the feed of the ox of heat stress phase, add medicinal GABA, addition is 0.5 ~ 4.5g/d, feed after medicinal GABA is mixed with feed, within 20 days, be a course for the treatment of, feed altogether 60 days 3 courses for the treatment of, freely drink water; Cattle feed can, with the concentrate supplement coordinated by corn, dregs of beans etc., also can select the coarse fodders such as herbage, straw, vinasse to supplement material.
Clinical practice effect:
On September 4,1 day to 2015 July in 2015 carries out following experimental study by the using method of the additive for preventing and treating beef cattle heat stress syndrome described in embodiment 1:
1. the comfort index of beef cattle feeding environment:
Temperature, hygrometer comfort index in table 1 Jin Jiang River in summer ox feeding environment
2. in the present invention, the anti-heat stress effect of GABA additive is as shown in table 2:
Table 2 additive of the present invention is on the impact of Jin Jiang River yellow cattle blood Endocrine hormone levels under heat stress condition
Note: in table 2, upper table expression is compared with a line, and the different lowercase alphabet of subscript shows significant difference (P < 0.05), and different lowercase alphabet differential is different not significantly (P > 0.05).
3. additive of the present invention is shown in Table 3 the impact of daily gain, feed intake and feed-weight ratio after Jin Jiang River ox test under heat stress condition:
Table 3 additive of the present invention is to the shadow of daily gain, feed intake and feed-weight ratio after Jin Jiang River ox test under heat stress condition
In table 3, subscript represents that same row compare, and the different capitalization of subscript represents significant difference (P < 0.05), and identical capitalization represents difference not significantly (P > 0.05).
Clinical experimental study shows, uses additive of the present invention in beef cattle feeding, effectively can alleviate heat stress and other stress reactions of beef cattle, reduces beef cattle endocrine hormone cortisol (COR) level, improves trilute (T
3), thyroxine (T
4) content; Improve the daily gain of heat stress beef cattle, improve the production performance of beef cattle, in 60 days that add GABA additive, beef cattle average daily gain improves 125% (P < 0.05) than control group, and feed-weight ratio significantly reduces.
Shown by above-mentioned test, the present invention is particularly useful for southern summer high temperature, high humidity environment, can be used for the physiological responses to heat stress of control in summer growth beef cattle and fattening beef cattle.
Above the better embodiment of this patent is explained in detail, but this patent is not limited to above-mentioned embodiment, in the ken that one skilled in the relevant art possesses, various change can also be made under the prerequisite not departing from this patent aim.
Claims (7)
1. for preventing and treating additive and the using method thereof of beef cattle heat stress syndrome, it is characterized in that, described additive is medicinal GABA, and described method is: in the feed of the beef cattle of heat stress phase, add medicinal GABA.
2. additive for preventing and treating beef cattle heat stress syndrome according to claim 1 and using method thereof, it is characterized in that, the addition of described medicinal GABA is 0.5 ~ 4.5g/d, feeds after being mixed by medicinal GABA with feed.
3., according to claim 1-2 arbitrary described additive and using method thereof for preventing and treating beef cattle heat stress syndrome, it is characterized in that, 20 days be a course for the treatment of.
4., according to claim 1-2 arbitrary described additive and using method thereof for preventing and treating beef cattle heat stress syndrome, it is characterized in that, feed 60 days 3 courses for the treatment of, freely drink water.
5. additive for preventing and treating beef cattle heat stress syndrome according to claim 1 and using method thereof, is characterized in that, described cattle feed adopts the concentrate supplement coordinated by corn, dregs of beans.
6. additive for preventing and treating beef cattle heat stress syndrome according to claim 1 and using method thereof, is characterized in that, described cattle feed adopts the coarse fodder coordinated by herbage, straw, vinasse to supplement material.
7. additive for preventing and treating beef cattle heat stress syndrome according to claim 1 and using method thereof, is characterized in that, described beef cattle is made a living ox and the fattening beef cattle of putting on flesh.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510923423.5A CN105533170A (en) | 2015-12-14 | 2015-12-14 | Use method of additive for preventing and treating heat stress syndromes of beef cattle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510923423.5A CN105533170A (en) | 2015-12-14 | 2015-12-14 | Use method of additive for preventing and treating heat stress syndromes of beef cattle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105533170A true CN105533170A (en) | 2016-05-04 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510923423.5A Pending CN105533170A (en) | 2015-12-14 | 2015-12-14 | Use method of additive for preventing and treating heat stress syndromes of beef cattle |
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| Country | Link |
|---|---|
| CN (1) | CN105533170A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106173294A (en) * | 2016-07-13 | 2016-12-07 | 四川贡牛生物饲料有限公司 | Ruminant stomach animal is fattened growth-promoting feedstuff additive |
| CN110074263A (en) * | 2019-05-11 | 2019-08-02 | 吴建云 | A kind of beef cattle anti-heat stress green Chinese herbal medicine composite feed additive formula |
| CN111820326A (en) * | 2019-04-16 | 2020-10-27 | 南京农业大学 | Beef cattle heat stress resistant feed additive for fattening period in southern damp-heat environment and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102246912A (en) * | 2011-07-06 | 2011-11-23 | 浙江大学 | Rumen bypass GABA cow concentrate |
| CN103719551A (en) * | 2013-12-27 | 2014-04-16 | 柳州市青钱柳农业科技开发有限公司 | Preparation method of GABA (gamma-aminobutyric acid)-rich silage |
-
2015
- 2015-12-14 CN CN201510923423.5A patent/CN105533170A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102246912A (en) * | 2011-07-06 | 2011-11-23 | 浙江大学 | Rumen bypass GABA cow concentrate |
| CN103719551A (en) * | 2013-12-27 | 2014-04-16 | 柳州市青钱柳农业科技开发有限公司 | Preparation method of GABA (gamma-aminobutyric acid)-rich silage |
Non-Patent Citations (1)
| Title |
|---|
| 徐同锏: "包被γ-氨基丁酸对奶牛热应激的防治效果及机理的研究", 《中国优秀硕士学位论文全文数据库 农业科技辑》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106173294A (en) * | 2016-07-13 | 2016-12-07 | 四川贡牛生物饲料有限公司 | Ruminant stomach animal is fattened growth-promoting feedstuff additive |
| CN111820326A (en) * | 2019-04-16 | 2020-10-27 | 南京农业大学 | Beef cattle heat stress resistant feed additive for fattening period in southern damp-heat environment and application thereof |
| CN110074263A (en) * | 2019-05-11 | 2019-08-02 | 吴建云 | A kind of beef cattle anti-heat stress green Chinese herbal medicine composite feed additive formula |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
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| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160504 |