CN105497519A - Preparation method for radix ginseng rubra-colla corii asini cell-wall breaking superfine powder - Google Patents
Preparation method for radix ginseng rubra-colla corii asini cell-wall breaking superfine powder Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
Abstract
The invention belongs to the technical field of food and health care food research and development, and relates to a preparation method for radix ginseng rubra-colla corii asini cell-wall breaking superfine powder. The preparation method comprises the steps that Korea fresh garden ginseng is processed into radix ginseng rubra, radix ginseng rubra is pulverized into powder through a common pulverizer, and the powder is pulverized into micron-grade powder through an air-current mill or vibration mill; water, glucose and lysozyme beta-1,3-dextranase or protease are added into the radix ginseng rubra micron-grade powder, the materials are mixed to be uniform, the temperature is controlled at 40 DEG C-45 DEG C, the pH is controlled at 5-5.5, the materials are kept under the conditions for 72-96 h, and then fermented radix ginseng rubra micron-grade powder is obtained; colla corii asini, radix polygonati officinalis and dioscorea opposita are mixed and pulverized into micron-grade powder, the micron-grade powder is mixed with the radix ginseng rubra micron-grade powder, dry granulating, drying and particle sizing are performed, and then the radix ginseng rubra-colla corii asini cell-wall breaking superfine powder is obtained; or the colla corii asini, radix polygonati officinalis and dioscorea opposita micron-grade powder is evenly mixed with the fermented radix ginseng rubra micron-grade powder, dry or wet granulating is performed, and then the radix ginseng rubra-colla corii asini cell-wall breaking superfine powder is obtained. The radix ginseng rubra-colla corii asini cell-wall breaking superfine powder has the functions of tonifying Qi, enriching the blood, resisting oxidation, cancers and aging and improving the memory and the immunity.
Description
Technical field
Technical field researched and developed by food belonging to the present invention and health food.The present invention relates to a kind of Radix Ginseng
The preparation method of Colla Corii Asini cell wall breaking superfine powder.Product of the present invention has QI invigorating, enriches blood, antioxidation, anticancer, defying age, raising memory, improve the function of immunity.
Background technology
1. Radix Ginseng
Radix Ginseng is the root and rhizome of Araliaceae Araliaeeae perennial plant PanaxginsengC.A.Meyer..Radix Ginseng is called as " king of Chinese medicine ", have the good reputation of " national treasure ".Radix Ginseng medical value is very high, strengthening by means of tonics effect to human body and the prevention effect to various diseases very remarkable, motherland's Chinese medicine has the effect of " Radix Ginseng sweet in the mouth; strongly invigorating primordial QI; spleen reinforcing, QI invigorating, the mind calming and mentality promoting, to slake thirst and help produce saliva; regulating menstruation nourishing the stomach, life lengthening ", and research in recent years achievement shows: Radix Ginseng has antioxidation, anticancer, defying age, raising memory, improves the functions such as immunity.
Radix Ginseng belongs to traditional Chinese crude drug, for Chinese medicine and healthy food material.2009, " Radix Ginseng food " international standard was approved in Codex Alimentary Commission (CAC) the 32nd conference, and regulation artificial growth Radix Ginseng can be used for food.Jilin Province of China is Radix Ginseng main producing region, and the culture of ginseng gross area was basically stable at 3,500 ten thousand square meter in recent years, year finished product Radix Ginseng about 4000 tons, Radix Ginseng output has accounted for 80% of the whole nation, accounts for about 70% of global output.
For developing the ginseng resource of China's abundant, Radix Ginseng is included in bread and cheese management by the suggestion of government of Jilin Province.The long-term edible safety appraisal of artificial growth Radix Ginseng of having organized scientific research institution to carry out of Department of Public Health of Jilin Province, result of study shows, in rated condition and dosage range, artificial growth Radix Ginseng is to animal free of toxic effects, and it is safe that healthy population eats artificial growth Radix Ginseng.To this, my portion has carried out the relevant demonstration of artificial growth Radix Ginseng together with multidisciplinary experts of Departmental organization such as the Ministry of Agriculture, Administration of Food and Drug, Department of Health.
2010, Radix Ginseng " integration of edible and medicinal herbs " pilot that government of Jilin Province carries out, and promulgated new " Ginseng In Jilin Province management method ", wherein clear stipulaties, " Radix Ginseng may be used for the production of food, medicine, health food, food additive and the product such as daily chemicals, artware ", here Radix Ginseng refers to artificial growth Radix Ginseng, and this way came into effect on March 1st, 2011.
2011, Ministry of Public Health receives artificial growth Radix Ginseng as after the application of new resource food, through organizing the aspect experts such as medical science, Chinese medicine, agricultural, food, nutrition, toxicity, pharmacology and technique to safety, activity and the nutritional labeling of artificial growth Radix Ginseng, being not suitable for the aspects such as crowd and auditing, it is safe for thinking that healthy population eats artificial growth Radix Ginseng according to edible limitation.In March, 2012, Ministry of Public Health just approval artificial growth Radix Ginseng is that new resource food solicits relevant department's suggestion, openly consults on to society simultaneously.
According to artificial growth Radix Ginseng edible safety assessment result, Ministry of Public Health announces 2012 No. 17, according to the regulation of " People's Republic of China's the law of food safety " and " new resource food management method ", the Radix Ginseng of Ministry of Public Health official approval less than 5 years and 5 years artificial growths is new resource food.This means, following in China, artificial growth Radix Ginseng can with right titles and proper words as food consumption.This measure is significant, will promote Chinese Radix Ginseng industry development further, and take part in international competition better.Because consumers in general are gradually to the understanding of Radix Ginseng Rubra drug effect and health care.Make Radix Ginseng Rubra and series of products deeply by the welcome of consumers in general, market capacity rises year by year.China increases the demand of Radix Ginseng, and international demand does not subtract, and this industrial prospect following is wide.
Huan Cui building Radix Ginseng is processed by Huan Cui building, Weihai Radix Ginseng Rubra Science and Technology Ltd. introduction Korea S's Radix Ginseng processing technique and domestic Radix Ginseng Rubra advanced machining technology by the fresh Park Ginseng in the Koryo originating from Korea S.
Radix Ginseng system is processed through steaming, toasting by the fresh ginseng in the Koryo originating from Korea S, in processing Radix Ginseng process, has new anticancer active constituent to produce.Radix Ginseng is not cool not warm yet, belongs to warm nature; Though Korean Ginseng is warm in nature but benefit property is strong, QI invigorating helps fire.Korean Ginseng divides again Radix Ginseng and Radix Ginseng Rubra, and insufficiency of the spleen hyperactivity of fire person should use Radix Ginseng, because of " life gas is cool, micro-bitter nourishing YIN "; The timid person of insufficiency of the spleen lung should use Radix Ginseng Rubra, " ripe temperature, sweet in the mouth YANG invigorating ".On the whole, Korean Ginseng is more suitable for the frank people of the old deficiency of vital energy and takes, the strong body constitution of energy, enhancing immunity.
Effect of Radix Ginseng:
(1) brain healthy: the people that hypomnesis and sports coordination ability are declined and be on the drink or the food of contact zones alcohol component, the people of medicine, Radix Ginseng has the effect improving mental working ability, memory reinforcing and improve cerebral ischemia obstacle.
(2) ease pain: some experts find by doing sensory nerve cell test, and Korean Ginseng is all helpful to the various pain symptom of health.
(3) anti-cancer and anticancer: the saponin constituent of Radix Ginseng and non-saponin constituent have the proliferation activity suppressing multiple cancerous cell, while also can anticancer shift.In addition, Radix Ginseng and anticarcinogen are with taking, and anticancer effect is better than independent anticarcinogen (mitomycin).This is because cancerous cell easily forms tolerance in chemotherapy of tumors, Radix Ginseng and anticarcinogen, with taking, strengthen the lethality to cancerous cell, alleviate the side effect of anticarcinogen.
(4) enhancing immunity: Radix Ginseng extract can recover the cellular immunity the declined reaction because taking the anticarcinogen (mitomycin) with immunotoxicity, especially ether extract can activate or strengthen cellular immunity, and the activity of natural killer cell, there is very large effect to raising immunity.
(5) diabetes are controlled: Radix Ginseng contains the material promoting insulin secretion and similar insulin action, and wherein ginsenoside can improve hyperglycemia, effectively controls the generation of diabetes.
(6) strong liver: have antihepatitic activity in Korean Ginseng composition, has the effect of removing toxic substances, the liver protecting and promotion liver regeneration, recovery.In addition, Radix Ginseng relieves the effect of alcohol in addition, eliminates the effect of being still drank after a night.
(7) regulate blood pressure: Radix Ginseng has blood vessel dilating effect, can improve blood circulation, saponin constituent wherein, by promoting vascular endothelial cell release nitric oxide, can reach hypotensive activity.
(8) resisting fatigue and resistance to compression: find after deliberation, continues to take Radix Ginseng and can improve motor capacity and fatigue alleviating, to promoting that the recovery of player's fatigue accumulation and prevention sports anemia have very great help; In addition, Radix Ginseng can also strengthen the tolerance to adverse environments such as low temperature (5 DEG C, O DEG C ,-10 DEG C) and high temperature (35 DEG C), by carrying out exquisite adjustment to pressure or environmental change, improves anti-pressure ability, maintains organism stability.
(9) improve Women’s climacteric obstacle: according to investigations, have the women of climacteric impairment property after taking Radix Ginseng, after having the people of 80% to admit to take Radix Ginseng, symptom is obviously improved.Expert claims, and these women, as adjusted consumption according to symptom, also can improve curative effect.
(10) male sexual disorder is improved: Radix Ginseng can prevent the male sexual disorder because pressure causes.Through clinical trial, after erection problem patient (90 people) takes Radix Ginseng, all make moderate progress in the degree of erection, libido and satisfaction etc.
(11) antioxidation and defying age: Radix Ginseng have suppress harmful active oxygen increase the antioxidant effect with lipid peroxidation.
2. Colla Corii Asini Colla Corii Asini starts from Qin Han, the history of existing more than 2000 year so far, for traditional nourishing, enriches blood top grade, is be primary raw material with donkey skin, puts the water of A Jing and make (glue not putting well water infusion is Colla Corii Asini, donkey glue).Colla Corii Asini originates in ancient Donga County, Shandong Province (the ancient A Jing in Acheng town, Yanggu County of today), and good person is with amber, transparent, odorless.Also known as Colla Corii Asini.
Effect of Colla Corii Asini and effect:
(1) immunity is improved: Colla Corii Asini has enhancing immunity, reduces the effect of disease.Be applicable to old, weakness due to chronic disease, the body constitution descender such as easily catch a cold.
(2) strengthening the tendons and bones: Colla Corii Asini nourishing blood liquid, the nourishing muscle and tendon of blood energy, liquid energy lubricating joint, enriches bone marrow, spinal cord, brains, therefore energy strengthening the tendons and bones, fluent joint, resists the injury of rheumatism.
(3) brain healthy: the plurality of active ingredients contained in Colla Corii Asini can alleviate study intense strain, makes brain and whole body fully be had a rest, and is conducive to improving body constitution, keeps fit the mind invigorating, full of vitality.Containing boy's bioactive peptide in Colla Corii Asini, energy enhancing body memory and raising identification ability, have stronger antifatigue effect.
(4) slowly aging is prolonged: Colla Corii Asini contains that gelatin is former, ossein, protein and various trace elements, several amino acids etc.These are all human nutrition important substance, have obvious defying age, life lengthening effect.
(5) anticancer: laboratory observation finds that Colla Corii Asini has dual regulation to cellular immunization.And have good potentiation to the activity of NK cell, and NK cell plays a role in the generation preventing tumor.In addition, Colla Corii Asini has promotion lymphocyte transformation effect, and can make decreased tumor growth, symptom is improved, and life extends.When using radiotherapy, chemotherapy, using Colla Corii Asini, can side effect be reduced, health invigorating, strengthen Drug tolerance.
(6) looks improving and the skin nourishing: Colla Corii Asini is skin care by enriching blood, is beneficial to skin care.Long-term taking can make of pink and healthy-looking, and skin is delicate, glossy.Nourishes rough skin, the good merchantable brand of looks improving and the skin nourishing.
(7) calcium supplementing effect: containing more rich calcareous in Colla Corii Asini, by the effect of glycine, promotes absorption and the storage of calcium, improves calcium balance in body, can prevention and therapy osteoporosis.Supplement ideal in middle-aged and old health.
(8) regulating menstruation is antiabortive: Colla Corii Asini may be used for the menoxenia because blood deficiency, blood stasis and heat in blood cause; Colla Corii Asini can nourishing YIN blood, and benefit punching is appointed, therefore can fetus nourishing, antiabortive, medical treatment pregnancy disease.To common liability to abortion, frequent fetal movement, even miscarriage has good therapeutical effect.
(9) blood vessel dilating: experiment proves that Colla Corii Asini has obvious inhibitory action to blood viscosity increase.Middle-aged and elderly people takes Colla Corii Asini can blood circulation promoting, improves microcirculation, the effects such as arrhythmia.
3. Rhizoma Polygonati Odorati Rhizoma Polygonati Odorati, formal name used at school: Polygonatumodoratum (Mill.) Druce is Liliaceae herbaceos perennial.
The effect of Rhizoma Polygonati Odorati:
Nourishing YIN and moistening the lung; Nourishing the stomach to promote the production of body fluid.Cough caused by dryness; Chronic cough; The dry throat and mouth of calentura cloudy liquid consumption wound; Interior-heat is quenched one's thirst; Deficiency of YIN diseases caused by exogenous pathogenic factor; Dizzy dizzy; Muscle arteries and veins spasm and pain.
(1) Rhizoma Polygonati Odorati sweet in the mouth greasiness, matter is soft and moisten, and is the good medicine of YIN nourishing and the production of body fluid promoting simply.Vitamin A contained in Rhizoma Polygonati Odorati, improves dry and cracked, rough skin situation, makes it soft lubrication.Play the effect of beauty and skin care.
(2) sterioside that contains of Rhizoma Polygonati Odorati, to the effect of cardiac muscle and Herba Convallariae preparation similar.Rhizoma Polygonati Odorati glycocide has cardiotonic to isolated frog heart, and effect and the Rhizoma Polygonati Odorati glycocide of Rhizoma Polygonati Odorati decoct are similar.
(3) Rhizoma Polygonati Odorati extractum lumbar injection, can strengthen burned mice Peritoneal macrophages Phagocytosis, improves Hemolysin level, improves the breeder reaction of splenocyte to ConA.
4. Rhizoma Dioscoreae is the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae Dioscoreaopposita
" book on Chinese herbal medicine is looked for the truth ": " enter in drugs for nourishing yin and should give birth to use, entering spleen reinforcing lung medicine should use by parching to brown." " this genus food, though gas temperature and put down, be the moon of spleen reinforcing lung.Be moistening fur, longue meat, sweet in the mouth is held concurrently salty, again can kidney tonifying reinforcing YIN-essence.”
(1) invigorating the spleen and replenishing QI: Rhizoma Dioscoreae plants trace element because being rich in 18 seed amino acids and more than 10, and other mineral, so have strengthening the spleen and stomach, tonifying the lung kidney, invigorating the spleen and replenishing QI, spleen invigorating tonify deficiency, to reinforce the kidney the effects such as beneficial essence, beneficial heart and tranquilizing mind, saying of " spleen invigorating tonification, taste essence being reinforced the kidney, controlled all kinds of diseases and ailments, treat five kinds of strain and seven kinds of impairment " is had in Li Shizhen (1518-1593 A.D.) Compendium of Material Medica.
(2) quench one's thirst and promote the production of body fluid: this Rhizoma Dioscoreae has the effect of life of quenching one's thirst: Chinese traditional treatment asthenia is quenched one's thirst in (diabetes) prescription often has Rhizoma Dioscoreae single to use, or share with other medicines, and effect is better.
(3) keep healthy: because fresh Rhizoma dioscoreae is rich in multivitamin, aminoacid and mineral, Human Lipid Metabolism can be prevented and treated abnormal, and arteriosclerosis, to safeguarding that insulin normal function also has certain effect, there is enhancing body immunity, beneficial heart and tranquilizing mind, rather cough Dingchuan, the health-care effects such as slow down aging.
(4) skin care: Yuan Dynasty taste expert Li Gao says: " control xerosis cutis and moisten it with this thing." Li Shizhen (1518-1593 A.D.) is write: " Rhizoma Dioscoreae can moisten fur." to nourishes rough skin, vigorous and graceful skin care has unique curative effect to Rhizoma Dioscoreae.
(5) Rhizoma Dioscoreae special pharmacological function: the copper ion in Rhizoma Dioscoreae and connective tissue have very big help to human development, obvious curative effects is had to vascular system disease, calcium in Rhizoma Dioscoreae, bone, osteoporosis are damaged to muscle and tendon injury, loss of tooth has high curative effect, also have good curative effect to chilblain, diabetes, hepatitis, children's's diarrhea, enuresis, baby's dyspepsia, ulcerative stomatitis, pulmonary tuberculosis, the inferior patient of woman in menstrual period band, using for a long time can be clear-headed and clear-sighted, life lengthening.
(6) feeding urges is controlled: in Rhizoma Dioscoreae, be rich in a large amount of protein, vitamin B group, vitamin C, vitamin E, glucose, crude protein aminoacid, bile alkaline, allantoin etc.; Wherein important nutritional labeling Rhizoma Dioscoreae soap is the precursor materials of synthesis estrogen, nourishing YIN and invigorating YANG, strengthens metabolic effect; And the phlegmatic temperament, zymigen etc. of the GL-PP composition contained in fresh tuber, cadiovascular lipidosis can be prevented, contribute to the absorption and digestion of gastrointestinal.
Cell wall breaking is a kind of superfine powder process technology, and Chinese medicine is pulverized according to usual manner, and its single particle is often made up of several or dozens of, and the sporoderm-broken rate of cell is extremely low.Chinese crude drug cell wall breaking micronizing process technology fully can discharge medical material effective ingredient.After cell wall breaking, intracellular moisture content oil content is moved out, and make micropartical surface presentation go out half moisture state, can form stable particle cluster between particle and particle, each particle cluster comprises the Chinese medicine ingredients of same ratio.The physical arrangement of this particle cluster is different with the various combination such as composition HLB value each in component (hydrophilic, lipophilic balance value), ductility, brokenness, proportion and different interactions.This structure is conducive to human body to the absorption of Chinese medicine and utilization.The fat-soluble enhancing of Chinese medicine, readily passes through adipose membrane, can carry rapidly the blood drug level in human body, reach the object of healing.Adopt cell wall breaking technology, first, the absorbance of medicine and food can be increased, improve its bioavailability.Chinese medicine is after ultra micro process, and medicine can disperse preferably, be dissolved in gastro-intestinal Fluid, and increases with the contact area of gastrointestinal mucosa, more easily by gastrointestinal absorption, thus substantially increases bioavailability.For mineral substance medical material, be equivalent to a part for water-insoluble materials, after ultra micro process, because its granularity reduces greatly, its dissolving in vivo, infiltration rate can be accelerated, improve its absorbtivity.Secondly, be conducive to retaining bioactive ingredients, improve drug effect, be conducive to retaining the bioactive ingredients of non-refractory and various nutritional labeling, thus improve drug effect.Finally, conservation, is convenient to application.Chinese medicine is after micronizing, and available smaller dose, obtains original prescription curative effect.
What China was to having " doctor's food homology, integration of edible and medicinal herbs " says, integration of edible and medicinal herbs is early on the books in history." dietetic therapy " is the marrow in health care theory.Nowadays the self health consciousness of people is strengthening day by day, and for life lengthening, remaining youthful forever has had more strong desire, and this ancient concept of " doctor's food homology, integration of edible and medicinal herbs ", another has been given people and has pursued the new implication gone back to nature.Along with China's medical model is changed to prevention, treatment, rehabilitation, health care comprehensive model by simple treatment, the Chinese medicine of some medicine-food two-purpose can be processed into micropowders, make various functional food, serve the whole mankind.The product applying the production of this technology has six large features: first is after Chinese medicine cell wall breaking, the good advantage such as absorbability, dissolubility, chemism, biological activity that it has, and has fabulous value to human body.Second is after Chinese medicine cell wall breaking, makes traditional Chinese medicine there occurs revolutionary change in production, treatment, innovation, use.3rd is the difficult problem solving the development of Chinese medicine long-standing problem related industry---use complicated, time-consuming and inconvenient.Utilize this technology can be made into exempt to decoct Chinese medicine, easy to use, additionally reduce dosage.4th is reduction of the drug residue in body, can also improve medicine quality, be beneficial to human health, the good condition for these industry product export earnings.5th hygienic quality that can improve Chinese medicine, when carrying out cell wall breaking micronizing to Chinese medicine, the worm's ovum suitable with cell dimensions also can be killed, thus alleviate disease and pest to the pollution of Chinese crude drug and infringement, make ultra micro Chinese medicine have pure natural property, ensure that integrity and the safety of Chinese medicine ingredients.6th is be beneficial to environmental protection, greening and vegetation protection, serves great function to the long-term of Chinese Medicine Industry and sustainable development.Cell wall breaking technology can saving Chinese medicaments 40% ~ 60%, and indivedual Chinese medicine can improve the drug effect of 4 times, and therefore, Chinese medicine cell wall breaking technology promotes huge economic benefit and social benefit by making commercial production.Technique can be widely used in the industries such as health product, non-staple food, food, medicine, beverage, cosmetics, herding, and market prospect and development space are very wide.
The preparation of Radix Ginseng Colla Corii Asini micron powder, adopt cell wall breaking technology, impel effective active matter stripping in cell, be easy to by human body overall absorption, mild in medicine property and, temperature and not dry, tonify without causing stagnation, there is QI invigorating, enrich blood, antioxidation, anticancer, defying age, raising memory, improve the function of immunity.
Micropowder refers to the powder of yardstick in micron level, has the dispersivity of height and large specific surface, thus makes it have unique physics and chemistry characteristic.Raw-food material is ground into and had both kept original natural feeding habits, there is again the raw-food material powder of micron order yardstick, ensure that micron order raw-food material powder and former raw-food material key property are consistent substantially, its cell wall is how broken, its nutritional labeling is more easily absorbed by the body, and its trophic function can be brought into play better.For the ease of packaging, carry and take, can adopt dry method or wet method that micron order raw-food material powder is made the granule of 0.2-3.0mm.
Summary of the invention
1. a preparation method for Radix Ginseng Colla Corii Asini cell wall breaking superfine powder, its feature is as follows:
(1) raw material weight is that Korea S produces the raw fresh Park Ginseng 100-400g in Koryo of 4-5, Colla Corii Asini 100-120g, Rhizoma Polygonati Odorati 200-220g, Rhizoma Dioscoreae 600-640g;
(2) by the fresh Park Ginseng in Korea S Koryo in (1), place in intelligent steaming ginseng cabinet, control heat temperature raising 60-95 DEG C of needs 0.5-1h; Control 95-98 DEG C continues to steam 2-2.5h; After controlling cooling 98-66 DEG C, 1-1.5h, take out, room temperature places 3.5-4h, becomes Radix Ginseng semi-finished product;
(3) the Radix Ginseng semi-finished product in (2) are put into intelligent drying chamber, by 5 temperature probes control 60-70 DEG C of dry 8-10h automatically, and automatically control every 0.5-1h air blast humidity discharging 1 time, take out, lower palpus;
(4) the Radix Ginseng semi-finished product after palpus lower in (3) are put into distilled panax water concentrated solution and flood 5-6h;
(5) by (4) through the impregnated Radix Ginseng semi-finished product of distilled panax water concentrated solution, night places 42-45h in glass room; Daytime is dry in the sun 27-30h in glass room;
(6) the Radix Ginseng semi-finished product of dry in the sun in (5) are put into intelligent drying chamber, by the control 51-55 DEG C of drying automatically of 5 temperature probes, and automatically control every 0.5-2h air blast humidity discharging 1 time, reach less than 12% to Radix Ginseng semi-finished product moisture, namely become Radix Ginseng;
(7) get moisture in (6) and reach the Radix Ginseng of less than 12%, 100,000 grades of clean areas, be crushed into 10-60 order powder with common grinder;
(8) by Radix Ginseng 10-60 order powder in (7), 100,000 grades of clean areas, control subzero 10-20 DEG C with airflow milling or vibromill and be crushed into 10-200 micropowder, be Radix Ginseng micropowder;
(9) or by Radix Ginseng 10-60 order powder in (7), 100,000 grades of clean areas, control subzero 10-20 DEG C with airflow milling or vibromill and be crushed into 10-200 micropowder, every gram of Radix Ginseng Rubra micropowder adds water 0.5-0.8g, glucose 0.5-0.8g, adds lysozyme β-1.3-glucanase 10-20mg or protease 10-20mg, mixing, control temperature 40-45 DEG C, pH5-5.5, keeps 72-96h, is the Radix Ginseng micropowder of fermenting;
(10) by Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae in (1), be 10-200 micropowder according to method co-grinding in (8), be Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae micropowder;
(11) Radix Ginseng micropowder in (8) or (9) and Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae micropowder in (10) are mixed, 100,000 grades of clean areas, put into vaporium and suck steam, mixing, tabletting, pulverizes this tabletting as 0.2-3.0mm granule, is Radix Ginseng Colla Corii Asini cell wall breaking superfine powder; Or Radix Ginseng micropowder in (8) or (9) and Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae micropowder in (10) are mixed, tabletting, this tabletting is pulverized as 0.2-3.0mm granule, is Radix Ginseng Colla Corii Asini cell wall breaking superfine powder; Or add 5-45% water or the ethanol soft material of micropowder weight, granulate, dry, granulate is 0.2-3.0mm granule, is Radix Ginseng Colla Corii Asini cell wall breaking superfine powder.
Percentage composition of the present invention is weight percentage.
Detailed description of the invention
The preparation method relating to a kind of Radix Ginseng Colla Corii Asini cell wall breaking superfine powder of the present invention comprises following examples, and the following examples can further illustrate the present invention, but do not limit the present invention in any way.
Embodiment 1:
1. a preparation method for Radix Ginseng Colla Corii Asini cell wall breaking superfine powder, its feature is as follows:
(1) raw material weight is that Korea S produces 4 years raw fresh Park Ginseng 100g in Koryo, Colla Corii Asini 120g, Rhizoma Polygonati Odorati 220g, Rhizoma Dioscoreae 640g;
(2) by the fresh Park Ginseng in Korea S Koryo in (1), place in intelligent steaming ginseng cabinet, control heat temperature raising 60-95 DEG C of needs 0.5h; Control 95 DEG C to continue to steam 2.5h; After controlling cooling 98-66 DEG C, 1h, take out, room temperature places 3.5h, becomes Radix Ginseng semi-finished product;
(3) the Radix Ginseng semi-finished product in (2) are put into intelligent drying chamber, automatically control 60 DEG C of dry 10h by 5 temperature probes, and automatically control every 0.5h air blast humidity discharging 1 time, take out, lower palpus;
(4) the Radix Ginseng semi-finished product after palpus lower in (3) are put into distilled panax water concentrated solution and flood 5h;
(5) by (4) through the impregnated Radix Ginseng semi-finished product of distilled panax water concentrated solution, night places 42h in glass room; Daytime is dry in the sun 30h in glass room;
(6) the Radix Ginseng semi-finished product of dry in the sun in (5) are put into intelligent drying chamber, automatically 51 DEG C of dryings are controlled by 5 temperature probes, and automatically control every 0.5h air blast humidity discharging 1 time, reach less than 12% to Radix Ginseng semi-finished product moisture, namely become Radix Ginseng;
(7) get moisture in (6) and reach the Radix Ginseng of less than 12%, 100,000 grades of clean areas, be crushed into 10 order powder with common grinder;
(8) by Radix Ginseng 10 order powder in (7), 100,000 grades of clean areas, control subzero 10 DEG C with airflow milling or vibromill and be crushed into 10 micropowder, be Radix Ginseng micropowder;
(9) or by Radix Ginseng 10 order powder in (7), 100,000 grades of clean areas, control subzero 10 DEG C with airflow milling or vibromill and be crushed into 10 micropowder, every gram of Radix Ginseng Rubra micropowder adds water 0.5g, glucose 0.5g, adds lysozyme β-1.3-glucanase 10mg or protease 10mg, mixing, control temperature 40 DEG C, pH5.5, keeps 96h, is the Radix Ginseng micropowder of fermenting;
(10) by Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae in (1), be 10 micropowder according to method co-grinding in (8), be Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae micropowder;
(11) Radix Ginseng micropowder in (8) or (9) and Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae micropowder in (10) are mixed, 100,000 grades of clean areas, put into vaporium and suck steam, mixing, tabletting, pulverizes this tabletting as 0.2mm granule, is Radix Ginseng Colla Corii Asini cell wall breaking superfine powder; Or Radix Ginseng micropowder in (8) or (9) and Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae micropowder in (10) are mixed, tabletting, this tabletting is pulverized as 0.2mm granule, is Radix Ginseng Colla Corii Asini cell wall breaking superfine powder; Or add 5% water or the ethanol soft material of micropowder weight, granulate, dry, granulate is 0.2mm granule, is Radix Ginseng Colla Corii Asini cell wall breaking superfine powder.
Embodiment 2:
1. a preparation method for Radix Ginseng Colla Corii Asini cell wall breaking superfine powder, its feature is as follows:
(1) raw material weight is that Korea S produces 5 years raw fresh Park Ginseng 400g in Koryo, Colla Corii Asini 100g, Rhizoma Polygonati Odorati 200g, Rhizoma Dioscoreae 600g;
(2) by the fresh Park Ginseng in Korea S Koryo in (1), place in intelligent steaming ginseng cabinet, control heat temperature raising 60-95 DEG C of needs 1h; Control 98 DEG C to continue to steam 2h; After controlling cooling 98-66 DEG C, 1.5h, take out, room temperature places 4h, becomes Radix Ginseng semi-finished product;
(3) the Radix Ginseng semi-finished product in (2) are put into intelligent drying chamber, automatically control 70 DEG C of dry 8h by 5 temperature probes, and automatically control every 1h air blast humidity discharging 1 time, take out, lower palpus;
(4) the Radix Ginseng semi-finished product after palpus lower in (3) are put into distilled panax water concentrated solution and flood 6h;
(5) by (4) through the impregnated Radix Ginseng semi-finished product of distilled panax water concentrated solution, night places 45h in glass room; Daytime is dry in the sun 27h in glass room;
(6) the Radix Ginseng semi-finished product of dry in the sun in (5) are put into intelligent drying chamber, automatically 55 DEG C of dryings are controlled by 5 temperature probes, and automatically control every 2h air blast humidity discharging 1 time, reach less than 12% to Radix Ginseng semi-finished product moisture, namely become Radix Ginseng;
(7) get moisture in (6) and reach the Radix Ginseng of less than 12%, 100,000 grades of clean areas, be crushed into 60 order powder with common grinder;
(8) by Radix Ginseng 60 order powder in (7), 100,000 grades of clean areas, control subzero 20 DEG C with airflow milling or vibromill and be crushed into 200 micropowder, be Radix Ginseng micropowder;
(9) or by Radix Ginseng 60 order powder in (7), 100,000 grades of clean areas, control subzero 20 DEG C with airflow milling or vibromill and be crushed into 200 micropowder, every gram of Radix Ginseng Rubra micropowder adds water 0.8g, glucose 0.8g, adds lysozyme β-1.3-glucanase 20mg or protease 20mg, mixing, control temperature 45 DEG C, pH5, keeps 72h, is the Radix Ginseng micropowder of fermenting;
(10) by Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae in (1), be 200 micropowder according to method co-grinding in (8), be Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae micropowder;
(11) Radix Ginseng micropowder in (8) or (9) and Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae micropowder in (10) are mixed, 100,000 grades of clean areas, put into vaporium and suck steam, mixing, tabletting, pulverizes this tabletting as 3.0mm granule, is Radix Ginseng Colla Corii Asini cell wall breaking superfine powder; Or Radix Ginseng micropowder in (8) or (9) and Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae micropowder in (10) are mixed, tabletting, this tabletting is pulverized as 3.0mm granule, is Radix Ginseng Colla Corii Asini cell wall breaking superfine powder; Or add 45% water or the ethanol soft material of micropowder weight, granulate, dry, granulate is 3.0mm granule, is Radix Ginseng Colla Corii Asini cell wall breaking superfine powder.
Claims (1)
1. a preparation method for Radix Ginseng Colla Corii Asini cell wall breaking superfine powder, its feature is as follows:
(1) raw material weight is that Korea S produces the raw fresh Park Ginseng 100-400g in Koryo of 4-5, Colla Corii Asini 100-120g, Rhizoma Polygonati Odorati 200-220g, Rhizoma Dioscoreae 600-640g;
(2) by the fresh Park Ginseng in Korea S Koryo in (1), place in intelligent steaming ginseng cabinet, control heat temperature raising 60-95 DEG C of needs 0.5-1h; Control 95-98 DEG C continues to steam 2-2.5h; After controlling cooling 98-66 DEG C, 1-1.5h, take out, room temperature places 3.5-4h, becomes Radix Ginseng semi-finished product;
(3) the Radix Ginseng semi-finished product in (2) are put into intelligent drying chamber, by 5 temperature probes control 60-70 DEG C of dry 8-10h automatically, and automatically control every 0.5-1h air blast humidity discharging 1 time, take out, lower palpus;
(4) the Radix Ginseng semi-finished product after palpus lower in (3) are put into distilled panax water concentrated solution and flood 5-6h;
(5) by (4) through the impregnated Radix Ginseng semi-finished product of distilled panax water concentrated solution, night places 42-45h in glass room; Daytime is dry in the sun 27-30h in glass room;
(6) the Radix Ginseng semi-finished product of dry in the sun in (5) are put into intelligent drying chamber, by the control 51-55 DEG C of drying automatically of 5 temperature probes, and automatically control every 0.5-2h air blast humidity discharging 1 time, reach less than 12% to Radix Ginseng semi-finished product moisture, namely become Radix Ginseng;
(7) get moisture in (6) and reach the Radix Ginseng of less than 12%, 100,000 grades of clean areas, be crushed into 10-60 order powder with common grinder;
(8) by Radix Ginseng 10-60 order powder in (7), 100,000 grades of clean areas, control subzero 10-20 DEG C with airflow milling or vibromill and be crushed into 10-200 micropowder, be Radix Ginseng micropowder;
(9) or by Radix Ginseng 10-60 order powder in (7), 100,000 grades of clean areas, control subzero 10-20 DEG C with airflow milling or vibromill and be crushed into 10-200 micropowder, every gram of Radix Ginseng Rubra micropowder adds water 0.5-0.8g, glucose 0.5-0.8g, adds lysozyme β-1.3-glucanase 10-20mg or protease 10-20mg, mixing, control temperature 40-45 DEG C, pH5-5.5, keeps 72-96h, is Radix Ginseng micropowder;
(10) by Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae in (1), be 10-200 micropowder according to method co-grinding in (8), be Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae micropowder;
(11) Radix Ginseng micropowder in (8) or (9) and Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae micropowder in (10) are mixed, 100,000 grades of clean areas, put into vaporium and suck steam, mixing, tabletting, pulverizes this tabletting as 0.2-3.0mm granule, is Radix Ginseng Colla Corii Asini cell wall breaking superfine powder; Or Radix Ginseng micropowder in (8) or (9) and Colla Corii Asini, Rhizoma Polygonati Odorati, Rhizoma Dioscoreae micropowder in (10) are mixed, tabletting, this tabletting is pulverized as 0.2-3.0mm granule, is Radix Ginseng Colla Corii Asini cell wall breaking superfine powder; Or add 5-45% water or the ethanol soft material of micropowder weight, granulate, dry, granulate is 0.2-3.0mm granule, is Radix Ginseng Colla Corii Asini cell wall breaking superfine powder.
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| CN108157940A (en) * | 2018-01-08 | 2018-06-15 | 杭州荣泽生物科技有限公司 | The preparation method of Periostracum cicadae pulvis |
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| CN1628749A (en) * | 2004-10-20 | 2005-06-22 | 北京东方兴企食品工业技术有限公司 | Eatable ants and its preparation method |
| CN104783163A (en) * | 2015-04-27 | 2015-07-22 | 威海环翠楼红参科技有限公司 | Preparation method of novel resource food Korean red ginseng wall-broken micron particles |
| CN104856037A (en) * | 2015-06-05 | 2015-08-26 | 威海环翠楼红参科技有限公司 | Preparing method of novel-resource food that is Korean red ginseng wall-broken powder preparation |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1628749A (en) * | 2004-10-20 | 2005-06-22 | 北京东方兴企食品工业技术有限公司 | Eatable ants and its preparation method |
| CN104783163A (en) * | 2015-04-27 | 2015-07-22 | 威海环翠楼红参科技有限公司 | Preparation method of novel resource food Korean red ginseng wall-broken micron particles |
| CN104856037A (en) * | 2015-06-05 | 2015-08-26 | 威海环翠楼红参科技有限公司 | Preparing method of novel-resource food that is Korean red ginseng wall-broken powder preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108157940A (en) * | 2018-01-08 | 2018-06-15 | 杭州荣泽生物科技有限公司 | The preparation method of Periostracum cicadae pulvis |
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