CN105497306A - Externally applied Zhuang-national composition for treating damp-heat type chronic pelvic inflammatory disease - Google Patents

Externally applied Zhuang-national composition for treating damp-heat type chronic pelvic inflammatory disease Download PDF

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CN105497306A
CN105497306A CN201511027041.0A CN201511027041A CN105497306A CN 105497306 A CN105497306 A CN 105497306A CN 201511027041 A CN201511027041 A CN 201511027041A CN 105497306 A CN105497306 A CN 105497306A
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inflammatory disease
damp
pelvic inflammatory
chronic pelvic
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方刚
梅巧
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Guangxi University of Chinese Medicine
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Guangxi University of Chinese Medicine
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

Abstract

The invention belongs to the field of national medicines, and discloses an externally applied Zhuang-national composition for treating damp-heat type chronic pelvic inflammatory disease. The composition is prepared from the following raw materials in parts by weight: 3-6 parts of argyreia pierreana, 1-3 parts of begonia fimbristipula, 1-3 parts of angelica citriodora hance, 3-6 parts of ovateleaf holly bark, 3-6 parts of common gendarussa herb, 3-12 parts of cherokee rose roots, 0.5-2 parts of safflower carthamus, 3-6 parts of callicarpa macrophylla, 1-2 parts of radix angelicae and 0.5-1 part of clove. The composition is an application preparation, and is prepared from Zhuang-national medicinal materials and traditional Chinese medicinal herbs having effects of clearing heat, inducing diuresis, removing toxicity, regulating qi circulation, relieving pain, removing stasis, dredging collaterals, dredging dragon channel and fire channel and the like, and can be used for nourishing deficiency of a human body, dredging stagnation of the dragon and fire channels, eliminating damp and heat and removing stasis and toxicity, so that sky, earth and vital energies can synchronously run to treat damp-heat type chronic pelvic inflammatory disease, and is an effective medicine for treating damp-heat type chronic pelvic inflammatory disease.

Description

A kind of Externally-applied Zhuang medicine compositions for the treatment of damp-heat type chronic pelvic inflammatory disease
Technical field
The invention belongs to national medicine field, be specifically related to a kind of Externally-applied Zhuang medicine compositions for the treatment of damp-heat type chronic pelvic inflammatory disease.
Background technology
Chronic pelvic inflammatory disease refers to one group of infectious disease of reproductive tract and surrounding tissue thereof in women, and mainly comprise endometritis, salpingitis, tubo-ovarian abscess, pelvioperitonitis etc., its course of disease is more than 1 year.Be common gynecological disease and frequently-occurring disease, cure rate is low, has a strong impact on work and the life of women.Doctor trained in Western medicine is greatly improved to its Treatment and diagnosis technology clinically, but still has many aspects not enough, therefore its research carried out also more and more is subject to the attention of Chinese scholars.
Strong medicine is the important component part of China's national medicine, in the disease preventing and treating practice of its nearly one thousand years, sums up and have accumulated the experience of preventing and treating chronic pelvic inflammatory disease in a large number.Chronic pelvic inflammatory disease belongs to the sick categories such as " through the Yin ", " grand leucorrhea " of strong doctor, strong medical knowledge opinion thinks that the basic reason of chronic pelvic inflammatory disease is that human righteousness is not enough, the evil poison such as damp and hot, cold-damp is invaded in taking advantage of a weak point in opponent's defence, make the poison such as pyretic toxicity, noxious dampness, expectorant poison evil interior raw, the change of disease is to Long Lu, Huo Lu, fight mutually with QI and blood and tie, anus, water channel, air flue (three roads) and two-way function are neglected one's duty, the QI-blood circulation stasis of blood is stagnant not smooth, and build up in interior, road is obstructed, QI and blood ecchymosis is gradually amassed, with the passing of time, Heaven, Earth and Man three gas can not be synchronous for the course of disease, and send out as primary disease.Control with the strong medicine of the effects such as clearing away heat-damp and promoting diuresis removing toxic substances, regulating QI to relieve pain, disperse blood stasis and dredge collateral, Tong Longlu fire road and Chinese herbal medicine composition, dredge the stagnant of Long Luhuo road, eliminating damp-heat ecchymosis, makes Heaven, Earth and Man three be so incensed that to treat damp-heat type chronic pelvic inflammatory disease with synchronous operation.Inventor, in clinical practice for many years, sums up a kind of strong drug composition for the treatment of damp-heat type chronic pelvic inflammatory disease, this strong drug composition is evident in efficacy, low cost, and clinic is applied.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of Externally-applied Zhuang medicine compositions for the treatment of damp-heat type chronic pelvic inflammatory disease.This drug regimen adopts the strong medicine and Chinese herbal medicine composition with effects such as clearing away heat-damp and promoting diuresis removing toxic substances, regulating QI to relieve pain, disperse blood stasis and dredge collateral, Tong Longlu fire roads, dredge the stagnant of Long Luhuo road, eliminating damp-heat ecchymosis, makes Heaven, Earth and Man three be so incensed that to treat damp-heat type chronic pelvic inflammatory disease with synchronous operation.And there is the advantages such as evident in efficacy, economical and practical.
The present invention solves the problems of the technologies described above by the following technical programs:
A kind of Externally-applied Zhuang medicine compositions for the treatment of damp-heat type chronic pelvic inflammatory disease, its raw material, with parts by weight, comprises Cortex Hibisci 3-6 part, Rhizoma Begoniae Fimbristipulatae 1-3 part, Radix osterici citriodori (Radix Angelicae Citriodorae) 1-3 part, Cortex Ilicis Rotundae 3-6 part, Herba Gendarussae 3-6 part, Radix Rosae Laevigatae 3-12 part, Flos Carthami 0.5-2 part, wear GUFENG 3-6 part, Radix Angelicae Dahuricae 1-2 part, Flos Caryophylli 0.5-1 part.
Its dosage form is applicator.
The present invention strengthens the characteristic of raw material included by drug composition:
Cortex Hibisci: be rattan and the branch and leaf of convolvulaceous plant white crane ArgyreiacautaLour. rattan; Nature and flavor: mildly bitter flavor, micro-acid, property is put down; Effect: astringing to arrest bleeding, preventing phlegm from forming and stopping coughing, eliminating stasis to stop pain, dispelling wind and removing obstruction in the collateral; Cure mainly: internal injury hemoptysis, metrorrhagia, menoxenia, leukorrhagia, traumatic injury, get injured by a fall shock and blockage of main and collateral channels.
Rhizoma Begoniae Fimbristipulatae: be tuber or the herb of Begoniaceae plant Radix Semiaquilegiae BegoniafimbristipulaHance.; Nature and flavor: sour in the mouth, puckery, cool in nature; Effect: clearing away heat and cooling blood, removing toxic substances, lung moistening, preventing phlegm from forming and stopping coughing, reducing swelling and alleviating pain; Cure mainly: pulmonary tuberculosis, bronchitis, pneumonia, cough, spitting of blood, epistaxis, lymphadenectasis, laryngopharynx swelling and pain, rheumatic ostalgia, traumatic injury, fracture, burn, scald.
Radix osterici citriodori (Radix Angelicae Citriodorae): be the root of Umbelliferae archangel Radix osterici citriodori (Radix Angelicae Citriodorae) AngelicacitriodoraHance.; Nature and flavor: bitter in the mouth, pungent, slightly warm in nature; Effect: promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis, eliminating damp, detoxifying; Cure mainly: stomachache, stomachache, angina pectoris, headache, rheumatic ostalgia, traumatic injury, colic, bronchitis, cirrhotic ascites, amenorrhea, amebic dysentery, parotitis, venom.
Cortex Ilicis Rotundae: the bark of holly plant Ilex rotunda Thunb. HexrotundaThumb., leaf; Nature and flavor: bitter in the mouth, cool in nature; Effect: heat-clearing and toxic substances removing, reducing swelling and alleviating pain, hemostasia and promoting granulation; Cure mainly: flu high heat, laryngopharynx swelling and pain, oedema due to nephritis, acute gastroenteritis, dysentery, gastrorrhagia, have blood in stool, gastroduodenal ulcer, pelvic inflammatory disease, adnexitis, fever of children, fracture, eczema, skin allergy, impetigo, burn, scald, venom.
Herba Gendarussae: strong Hahcangswngh by name is the stem and leaf of acanthaceous plant Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) GendarussavulgarisNees.; Nature and flavor: acrid in the mouth, hardship, property is put down; Tong Longlu, dispel the wind poison, except noxious dampness; Cure mainly: rheumatic arthralgia, dysmenorrhea, menoxenia, puerperal abdonimal pain, traumatic injury, fracture, unknown osteodynia.
Radix Rosae Laevigatae: be root or the root bark of rosaceous plant Fructus Rosae Laevigatae RosalaevigataMichx.; Nature and flavor: sour and astringent, property is put down; Effect: reinforcing the kidney and controlling nocturnal emission; Cure mainly: spermatorrhea, the enuresis, dysentery is had loose bowels, bleeding not during menses, uterine prolapse, haemorrhoids, scalds.
Flos Carthami: be the dried floral of feverfew Flos Carthami CarthamustinctoriusL..Nature and flavor: acrid in the mouth, warm in nature.Effect: promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.Cure mainly: amenorrhea due to stagnation of blood, dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal, lump in the abdomen, obstruction of qi in the chest and cardialgia, abdominal pain due to blood stasis, hypochondriac pain, traumatic injury, the stasis of blood be stagnant to swell and ache, the stagnant macule color of the stasis of blood is dark, the card such as galactopoiesis, stasis blocking headache, dizzy, apoplectic hemiplegia, sore throat, conjunctival congestion and swelling pain.
Wear the strength of character: be root and the branch and leaf of Verbenaceae Folium Callicarpae Macrophyllae Callicarpamacrophylla..Nature and flavor: bitter in the mouth, light, property is put down; Effect: hemostasis and anti-inflammation, expelling wind and removing dampness, reducing swelling and alleviating pain, granulation promoting reason mouth, diuresis; Cure mainly: eruptive syndrome, digestive tract hemorrhage, spitting of blood, epistaxis, wound hemorrhage, treating swelling and pain by traumatic injury, rheumatic ostalgia, menoxenia, leukorrhagia, infantile malnutrition, snakeworm and barking is bitten.
The Radix Angelicae Dahuricae: be the dry root of samphire Radix Angelicae Dahuricae Angelicadahurica (Fisch.exHoffm) Benth.etHook.f. or Radix angelicae dahuricae Angelicadahurica (Fisch.exHoffm) Benth.etHook.f.var.formosana (Boiss.) Shanet.yuan.; Nature and flavor: acrid in the mouth, hardship, warm in nature; Effect: the cold expelling that induces sweat, wind-expelling pain-stopping, clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis, dispelling wind for relieving itching; Cure mainly: anemofrigid cold, headache, toothache, rheumatic arthralgia, nasal sinusitis, leukorrhagia card, sore and toxic, skin rheumatism pruritus.
Flos Caryophylli: be the alabastrum of the drying of Tao Jin section plant of clove EugeniacaryophyllataThunb.; Nature and flavor: acrid in the mouth, warm in nature; Effect: warming middle-JIAO to send down the adverse QI, dispersing cold for relieving pain, warming the kidney to activate YANG; Cure mainly: gastrofrigid vomiting, singultus, coldness and pain in the epigastrium, sexual impotence, cold womb.
In side, Rhizoma Begoniae Fimbristipulatae, Cortex Hibisci are principal agent; Radix osterici citriodori (Radix Angelicae Citriodorae), Cortex Ilicis Rotundae, Herba Gendarussae three are side medicine; Radix Rosae Laevigatae, Flos Carthami are public medicine; Flos Caryophylli, the Radix Angelicae Dahuricae, to wear GUFENG be female medicine, and Quan Fangzhu helps male and female to share, wherein Rhizoma Begoniae Fimbristipulatae heat-clearing and toxic substances removing pain relieving, Cortex Hibisci eliminating stasis to stop pain, dispelling wind and removing obstruction in the collateral, and the two is in order to heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, Tong Longlu; Radix osterici citriodori (Radix Angelicae Citriodorae), Cortex Ilicis Rotundae, Herba Gendarussae promoting the circulation of QI to relieve pain, eliminating damp, detoxifying, help the power of principal agent; Radix Rosae Laevigatae is astringent or styptic treatment for spontaneous sweating, the pungent loose pain relieving of Flos Carthami, and one receives one falls apart, and both the anti-main side property of medicine too, inducing menstruation to relieve menalgia again; Wear GUFENG, the Radix Angelicae Dahuricae, Flos Caryophylli dampness removing anti-inflammatory analgetic, the short infiltration of fire-through path.Full side plays the merit on clearing away heat-damp and promoting diuresis removing toxic substances, regulating QI to relieve pain, disperse blood stasis and dredge collateral, Tong Longlu fire road altogether, and three road two-way are unimpeded, people from world three gas synchronous operation and hot and humid ecchymosis must be removed, and QI and blood is unobstructed.
The present invention has following effect:
There is strong medicine and the Chinese herbal medicine composition of the effects such as clearing away heat-damp and promoting diuresis removing toxic substances, regulating QI to relieve pain, disperse blood stasis and dredge collateral, Tong Longlu fire road, dredge the stagnant of Long Luhuo road, eliminating damp-heat ecchymosis, making Heaven, Earth and Man three be so incensed that to treat damp-heat type chronic pelvic inflammatory disease with synchronous operation, is the active drug for the treatment of damp-heat type chronic pelvic inflammatory disease.
Detailed description of the invention
Below by embodiment, the invention will be further described, but not as any restriction to scope.
Embodiment 1:
1. treat an Externally-applied Zhuang medicine compositions for damp-heat type chronic pelvic inflammatory disease, its raw material, with parts by weight, comprising:
Comprise Cortex Hibisci 6 parts, Rhizoma Begoniae Fimbristipulatae 2 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 3 parts, Cortex Ilicis Rotundae 4 parts, Herba Gendarussae 5 parts, Radix Rosae Laevigatae 8 parts, 1 part, Flos Carthami, wear GUFENG 3 parts, the Radix Angelicae Dahuricae 2 parts, Flos Caryophylli 0.5 part.
2. strong drug composition preparation method:
Take above-mentioned raw materials respectively by weight, cleaned by raw material, be ground into fine powder altogether, mixing, vial is deposited equipment and is used.Used time every agent powder 30g vaseline of getting it filled is modulated into pasty state, is placed in umbilicus place, with square yarn and surgery immobilization with adhesive tape.The dosage form of described strong drug composition is applicator.
3. application method: every day 1 dose, each subsides 2 hours, 7d is a course for the treatment of.
4. the effect after the treatment of damp-heat type chronic Patients with Pelvic Inflammatory Disease:
Gold so-and-so, female, 31 years old, people from Guilin City, suffered from damp-heat type chronic pelvic inflammatory disease 2 years, treats disease cured after 3 courses for the treatment of continuously, do not recur with this side.
Bring up so-and-so, female, 28 years old, Chenzhou City people, suffer from damp-heat type chronic pelvic inflammatory disease 3 years, treat disease cured after 3 courses for the treatment of continuously with this side, do not recur.
Embodiment 2:
1. treat an Externally-applied Zhuang medicine compositions for damp-heat type chronic pelvic inflammatory disease, its raw material, with parts by weight, comprising:
Comprise Cortex Hibisci 5 parts, Rhizoma Begoniae Fimbristipulatae 2 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 3 parts, Cortex Ilicis Rotundae 6 parts, Herba Gendarussae 6 parts, Radix Rosae Laevigatae 10 parts, 2 parts, Flos Carthami, wear GUFENG 5 parts, the Radix Angelicae Dahuricae 2 parts, Flos Caryophylli 1 part.
2. strong drug composition preparation method:
Take above-mentioned raw materials respectively by weight, cleaned by raw material, be ground into fine powder altogether, mixing, equipment use deposited by vial, and used time every agent powder 30g vaseline of getting it filled is modulated into pasty state, is placed in umbilicus place, with square yarn and surgery immobilization with adhesive tape.The dosage form of described strong drug composition is applicator.
3. application method: every day 1 dose, each subsides 3 hours, 7d is a course for the treatment of.
4. the effect after the treatment of damp-heat type chronic Patients with Pelvic Inflammatory Disease:
King so-and-so, female, 25 years old, people from Heng County, suffer from damp-heat type chronic pelvic inflammatory disease 4 years, after treating 4 courses for the treatment of continuously with this strong prescription, disease cured, did not recur.
Why so-and-so, female, 34 years old, people from Liuzhou City, suffer from damp-heat type chronic pelvic inflammatory disease 3 years, after treating 3 courses for the treatment of continuously with this strong prescription, disease cured, did not recur.
Below the clinical statistics data that patient uses medicine of the present invention:
1 basic document
Collect hospital-based outpatient obstetrical clinic go to a doctor patient 100 example, diagnose with reference to following diagnostic criteria.
2 diagnostic criterias
(1) diagnosis basis: " new Chinese medicine guideline of clinical investigations " (2002) with reference to Zheng Xiao cornel: once had acute pelvic inflammatory disease medical history.Symptom: lower abdominal pain, lumbosacral pain; There is the leucorrhea of purulence, companion's urinary tract infection symptom.Sign: purulent secretion appears in vagina, cervix uteri or body of uterus shake lifts pain, and palace is other tenderness, and side, uterus or bilateral thicken, and tenderness is obvious, and sacrum cardinal ligament increases thick, touches a tender spot or accessory installation.
(2) Accumulation of Dampness Heat and Blood Stasis demonstrate,proves dialectical foundation: " Gynecology of Chinese Medicine " with reference to Zhang Yuzhen chief editor is drafted: 1. primary symptom: lower abdominal pain, waist sacrum distending pain, profuse leukorrhea, yellow skin, and taste is smelly; 2. secondary disease: spiritlessness and weakness, low thermal fluctuation, menorrhagia or menostaxis or see unregular vaginal bleeding, abdominal pain in menstruation increases the weight of, yellow urine, is hard and dry or half congealed and not well.Body of the tongue: red tongue or dark red or limit is sharp has petechia ecchymosis, yellow and greasy fur.Pulse condition: stringy and rolling pulse or sliding number.
Above primary symptom 1., 2. at least one item, in leucorrhea amount, color, taste at least two, secondary disease possesses at least two.
(3) inclusive criteria: the diagnosis basis meeting chronic pelvic inflammatory disease; Chinese medical discrimination is Accumulation of Dampness Heat and Blood Stasis card; Repeatedly more than lower abdominal pain February; Age 20-45 year; Previously menolipsis disorder, infertile medical history; Be ready to accept this experimenter.
(4) Excluded cases standard: the diagnostic criteria not meeting chronic pelvic inflammatory disease; Chinese medical discrimination non-Accumulation of Dampness Heat and Blood Stasis card person; Age is greater than 45 years old or is less than 20 years old; Acute pelvic inflammatory disease person; Once cryptorrhea, uterine cavity organic disease person was there is before medical; There is non-inflammatory enclosed mass in B ultrasonic prompting attachment area; There are the Chronic consumptions persons such as tuberculosis, hyperthyroidism, severe anemia; Untoward reaction person is there is in medication process; Medical by regulation, standardized drug, data is not congruent to affect the treatment or cannot statistical disposition person.
2 experiment groupings
Patient is divided into 2 groups at random, comprises treatment group, matched group, often organize 50 examples.
3 therapeutic schemes
Treatment group: use Externally-applied Zhuang medicine compositions of the present invention to treat, raw material comprises Cortex Hibisci 6 parts, Rhizoma Begoniae Fimbristipulatae 2 parts, Radix osterici citriodori (Radix Angelicae Citriodorae) 3 parts, Cortex Ilicis Rotundae 4 parts, Herba Gendarussae 5 parts, Radix Rosae Laevigatae 8 parts, 1 part, Flos Carthami, wear GUFENG 3 parts, the Radix Angelicae Dahuricae 2 parts, Flos Caryophylli 0.5 part, above-mentioned raw materials parts by weights another name is got, clean, be ground into fine powder altogether, mixing, used time every agent powder 30g vaseline of getting it filled is modulated into pasty state, is placed in umbilicus place, with square yarn and surgery immobilization with adhesive tape, every day 1 dose, each 2 hours 7 days is a course for the treatment of;
Matched group: levofloxacin 500mg is oral, every day 1 time, metronidazole 400mg is oral, every day 2 times, and 7d is a course for the treatment of.
The equal medication for the treatment of group, matched group 21 days.
4 efficacy determinations
Draft with reference to the efficacy assessment standard of chronic pelvic inflammatory disease in " traditional Chinese medical science Clinical Researches of New Drugs guideline is tried ".Recovery from illness: clinical symptom disappearance, gynaecological examination and lab testing are all normal, have no outbreak in January; Effective: clinical symptoms is obviously improved, gynaecological examination and lab testing obviously improve, disease integration ﹥ 70% and ﹤ 95%; Effective: clinical symptom relief, gynaecological examination and lab testing slightly improve, disease integration ﹥ 30% and ﹤ 70%; Invalid: clinical symptoms has no and alleviates, gynaecological examination and lab testing have no improvement, even increase the weight of, disease integration ﹤ 30%.
5 statistical procedures
Adopt SPSS19.0 statistical software to analyze, measurement data adopts t inspection.P<0.05 is two groups and has diversity, has statistical significance.
6 experimental results
Treatment group: recovery from illness 23 example, effective 14 examples, effective 8 examples, invalid 5 examples, total effective rate 90%; Matched group: recovery from illness 11 example, effective 8 examples, effective 12 examples, invalid 19 examples, total effective rate 72%.Treatment group compares with matched group, and difference has statistical significance.Treatment group clinical efficacy is better than matched group.
Matched group and treatment group Clinical efficacy comparison
Note: compare with matched group, P<0.05.

Claims (2)

1. treat the Externally-applied Zhuang medicine compositions of damp-heat type chronic pelvic inflammatory disease for one kind, it is characterized in that: its raw material, with parts by weight, comprises Cortex Hibisci 3-6 part, Rhizoma Begoniae Fimbristipulatae 1-3 part, Radix osterici citriodori (Radix Angelicae Citriodorae) 1-3 part, Cortex Ilicis Rotundae 3-6 part, Herba Gendarussae 3-6 part, Radix Rosae Laevigatae 3-12 part, Flos Carthami 0.5-2 part, wear GUFENG 3-6 part, Radix Angelicae Dahuricae 1-2 part, Flos Caryophylli 0.5-1 part.
2. a kind of Externally-applied Zhuang medicine compositions for the treatment of damp-heat type chronic pelvic inflammatory disease as claimed in claim 1, is characterized in that: its dosage form is applicator.
CN201511027041.0A 2015-12-31 2015-12-31 Externally applied Zhuang-national composition for treating damp-heat type chronic pelvic inflammatory disease Pending CN105497306A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1682975A (en) * 2005-03-16 2005-10-19 广西灵峰药业有限公司 Medicine for treating pelvic inflammation and its producing method
CN103977258A (en) * 2014-05-28 2014-08-13 李建萍 Traditional Chinese medicament for treating abdominal lump type pelvic inflammation
CN104306523A (en) * 2014-09-26 2015-01-28 广西中医药大学 Yao drug preparation for treating chronic pelvic inflammation and preparation method thereof
CN104825790A (en) * 2015-04-17 2015-08-12 王�琦 Traditional Chinese medicine preparation used for treating chronic pelvic inflammatory disease
CN105168633A (en) * 2015-08-07 2015-12-23 高天生 Umbilicus application with rosa laevigata, glossy privet fruits and vaginal discharge cleaning function

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1682975A (en) * 2005-03-16 2005-10-19 广西灵峰药业有限公司 Medicine for treating pelvic inflammation and its producing method
CN103977258A (en) * 2014-05-28 2014-08-13 李建萍 Traditional Chinese medicament for treating abdominal lump type pelvic inflammation
CN104306523A (en) * 2014-09-26 2015-01-28 广西中医药大学 Yao drug preparation for treating chronic pelvic inflammation and preparation method thereof
CN104825790A (en) * 2015-04-17 2015-08-12 王�琦 Traditional Chinese medicine preparation used for treating chronic pelvic inflammatory disease
CN105168633A (en) * 2015-08-07 2015-12-23 高天生 Umbilicus application with rosa laevigata, glossy privet fruits and vaginal discharge cleaning function

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