CN105476732A - Artificial bone grain - Google Patents
Artificial bone grain Download PDFInfo
- Publication number
- CN105476732A CN105476732A CN201511024549.5A CN201511024549A CN105476732A CN 105476732 A CN105476732 A CN 105476732A CN 201511024549 A CN201511024549 A CN 201511024549A CN 105476732 A CN105476732 A CN 105476732A
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- CN
- China
- Prior art keywords
- lobe
- skeletal grain
- matrix
- bone
- grain according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
Abstract
The invention provides an artificial bone grain and belongs to the field of bone repairing devices. The problems of poor bone grain connecting firmness and the like existing in the design in the prior art are solved. The artificial bone grain comprises base bodies, wherein each base body comprises a plurality of protruding portions respectively extending towards all directions, the root portions of the protruding portions converge to form a central convergence portion, the protruding portions and the central convergence portion are connected to form an integral structure, and the protruding portions on each base body can be mutually clamped with the protruding portions on the adjacent base bodies. The artificial bone grain has the advantages of being reasonable in design and simple in structure, strengthening the adjacent bone grain connecting firmness through the clamping effect of the protruding portions, providing a growth environment for bone cells through growth channels in the bone grain and improving the connecting strength between the bone cells and the bone grain.
Description
Technical field
The invention belongs to bone repair fixture fields, especially relate to a kind of artificial skeletal grain.
Background technology
At field of orthopaedics, the Cranial defect caused by the many reasons such as severe trauma, bone tumor, osteomyelitis is very common.Bone renovating material conventional at present comprises autologous bone and metal prostheses.Autologous bone adds wound and the misery of patient, metal prostheses exists loosening, the problems such as fracture, therefore, artificial bone substitute materials skin grafing and mending Cranial defect becomes medical science emphasis, artificial bone (ArtificailBone) refers to the bioartificial materials that can substitute human bone or repair osseous tissue defect, when joint or the fracture for the treatment of bone need be replaced, optimal mode realizes self repairing of bone by function of tissue regeneration, but in most cases, human bone can not realize self and repair, such as bone necrosis, Bone and joint trauma, at this moment the help of artificial bone is just needed, artificial bone is by be used alone or different materials meets compound use and promotes knitting, its action principle comprises three aspects: osteogenesis effect: contain the living cells with differentiation osteogenic potential in osteogenesis material, there is bone formation effect, two is bone conduction: embedded material, by promoting the combination of host bone and graft materials surface, guides bone formation, three is self-bone grafting: its material is by providing a kind of biostimulation, and the cell differentiation of induction local cells or transplanting forms ripe osteoblast.Due to the material that artificial bone is in implant into body, so the artificial bone of medical use is all the skeletal grain structure adopting external diameter very little, there is environment and be unfavorable for that osteoblast is grown up in existing skeletal grain, connects the defects such as not firm between skeletal grain.
In order to solve prior art Problems existing, people have carried out long-term exploration, propose solution miscellaneous.Such as, Chinese patent literature discloses a kind of self-bone grafting artificial bone [application number: 201220149510.1], comprises the carrier be made up of calcium phosphate, it is characterized in that, the upper and lower surface of described carrier is all coated with one deck base layer; Described base layer outer surface is coated with biological active bone tissue inducing regeneration film.
Such scheme alleviates the problem of the growth of osteoblast in skeletal grain to a certain extent, but the program still also exists: the connection fastness between skeletal grain is low, the inner three-dimensional poor connectivity of skeletal grain, be unfavorable for the problems such as bonding strength is low of the growth of osteoblast in skeletal grain, osteoblast and skeletal grain inside.
Summary of the invention
The object of the invention is for the problems referred to above, provide a kind of reasonable in design, structure is simple, the artificial skeletal grain be connected firmly between skeletal grain.
For achieving the above object, present invention employs following technical proposal: artificial skeletal grain of the present invention, comprise matrix, matrix comprises the lobe that some one way or anothers respectively extend, the root of each lobe converges formation center pooled portion, and each lobe and center pooled portion are connected as a single entity structure, the lobe on each matrix can engage mutually with the lobe on adjacent base.Lobe on adjacent base engages the degree of being connected firmly that improve between skeletal grain mutually, and the lobe of matrix comprises several one way or another extensions respectively, make a skeletal grain can connect multiple skeletal grain at different directions simultaneously, thus form netted connection, further increase the firmness between skeletal grain and compactness.
Preferably, matrix is provided with some growth passages for bone cell growth.Growth passage is beneficial to the growth of osteocyte in skeletal grain inside, improves the bonding strength of osteocyte and skeletal grain inside.
Preferably, grow the both ends open of passage and lay respectively at matrix surface or at least one end opening is positioned at matrix surface.
Preferably, some growth passage is had at least to be interconnected in matrix.Further enhancing the degree of being connected firmly of osteocyte and skeletal grain inside.
Preferably, lobe is column and the size of lobe outer end is greater than the size of lobe root.Further enhance the engaging degree between skeletal grain, connection fastness between osteocyte and skeletal grain outer surface.
Preferably, the outer end of lobe is in expanding shape and surface is curved seamlessly transits, and the size of each lobe is identical with profile.Make skeletal grain and external parties to engaging skeletal grain between connection dynamics even, improve connective stability.
Preferably, the outer face of lobe is plane.When reducing patient activity, skeletal grain, to the injury of patient body inside, alleviates the pain of patient.
Preferably, lobe is provided with along the axially extended growth passage of lobe and the growth passage along the extension of lobe radial direction.
Preferably, the quantity of lobe is six, and wherein four lobe are at grade in cross distribution, and two other lobe is perpendicular to above-mentioned plane and coaxially arrange and lay respectively at the both sides of above-mentioned plane.Be convenient to skeletal grain all around up and down six direction be connected with adjacent skeletal grain.
Preferably, the internal diameter of each growth passage is identical or different or incomplete same.Different designs can be carried out to skeletal grain internal diameter, to meet the different needs according to the position of patient body Endoskeleton reparation.
Compared with prior art, the advantage of this artificial skeletal grain is: reasonable in design, structure simple, by the snap action of lobe, enhances the connection fastness of adjacent bone intergranular, growth passage in skeletal grain provides the growing environment of osteocyte, improves the bonding strength of osteocyte and skeletal grain.
Accompanying drawing explanation
Fig. 1 provides the structural representation of the embodiment of the present invention.
Fig. 2 provides the front view of the embodiment of the present invention.
In figure, matrix 1, lobe 101, center pooled portion 102, growth passage 2.
Detailed description of the invention
Below in conjunction with accompanying drawing, also by embodiment, the present invention is described in further detail, and following examples are explanation of the invention and the present invention is not limited to following examples.
As shown in Fig. 1 to 2, this artificial skeletal grain, comprise matrix 1, matrix 1 comprises the lobe 101 that some one way or anothers respectively extend, the root of each lobe 101 converges formation center pooled portion 102, and each lobe 101 and center pooled portion 102 are connected as a single entity structure, lobe 101 on each matrix 1 can engage mutually with the lobe 101 on adjacent base 1, lobe 101 on adjacent base 1 engages the degree of being connected firmly that improve between skeletal grain mutually, and the lobe 101 of matrix 1 comprises several one way or another extensions respectively, make a skeletal grain can connect multiple skeletal grain at different directions simultaneously, thus form netted connection, further increase the firmness between skeletal grain and compactness.
Particularly, matrix 1 is here provided with some growth passages 2 for bone cell growth, and growth passage 2 is beneficial to the growth of osteocyte in skeletal grain inside, improves the bonding strength of osteocyte and skeletal grain inside; The both ends open of growth passage 2 here lays respectively at matrix 1 surface or at least one end opening is positioned at matrix 1 surface; Here the some growth passage 2 that has at least is interconnected in matrix 1, further enhancing the degree of being connected firmly of osteocyte and skeletal grain inside; Here lobe 101 is in column and the size of lobe 101 outer end is greater than the size of lobe 101 root, further enhances the engaging degree between skeletal grain, connection fastness between osteocyte and skeletal grain outer surface.
Further, the outer end of lobe 101 is here in expanding shape and surface is curved seamlessly transits, and the size of each lobe 101 is identical with profile, make skeletal grain and external parties to engaging skeletal grain between connection dynamics even, improve connective stability; The outer face of lobe 101 is here plane, and when reducing patient activity, skeletal grain, to the injury of patient body inside, alleviates the pain of patient; Here lobe 101 is provided with along the axially extended growth passage 2 of lobe 101 and the growth passage 2 along the extension of lobe 101 radial direction; The quantity of lobe 101 is here six, wherein four lobe 101 are at grade in cross distribution, two other lobe 101 is perpendicular to above-mentioned plane and coaxially arrange and lay respectively at the both sides of above-mentioned plane, is convenient to skeletal grain and is connected with adjacent skeletal grain at all around upper and lower six direction; The internal diameter of each growth passage 2 is here identical or different or incomplete same, can carry out different designs, to meet the different needs according to the position of patient body Endoskeleton reparation to skeletal grain internal diameter.
Specific embodiment described herein is only to the explanation for example of the present invention's spirit.Those skilled in the art can make various amendment or supplement or adopt similar mode to substitute to described specific embodiment, but can't depart from spirit of the present invention or surmount the scope that appended claims defines.
Although more employ the terms such as matrix 1, lobe 101, center pooled portion 102, growth passage 2 herein, do not get rid of the probability using other term.These terms are used to be only used to describe and explain essence of the present invention more easily; The restriction that they are construed to any one additional is all contrary with spirit of the present invention.
Claims (10)
1. an artificial skeletal grain, comprise matrix (1), it is characterized in that: described matrix (1) comprises the lobe (101) that some one way or anothers respectively extend, the root of each lobe (101) converges formation center pooled portion (102), and each lobe (101) and center pooled portion (102) are connected as a single entity structure, the lobe (101) on each matrix (1) can engage mutually with the lobe (101) on adjacent base (1).
2. artificial skeletal grain according to claim 1, is characterized in that, described matrix (1) is provided with some growth passages (2) for bone cell growth.
3. artificial skeletal grain according to claim 2, is characterized in that, the both ends open of described growth passage (2) lays respectively at matrix (1) surface or at least one end opening is positioned at matrix (1) surface.
4. artificial skeletal grain according to claim 3, is characterized in that, has at least some growth passage (2) to be interconnected in matrix (1).
5. the artificial skeletal grain according to Claims 2 or 3 or 4, is characterized in that, described lobe (101) is in column and the size of lobe (101) outer end is greater than the size of lobe (101) root.
6. artificial skeletal grain according to claim 5, is characterized in that, the outer end of described lobe (101) is in expanding shape and surface is curved seamlessly transits, and the size of each lobe (101) is identical with profile.
7. artificial skeletal grain according to claim 6, is characterized in that, the outer face of described lobe (101) is plane.
8. artificial skeletal grain according to claim 5, it is characterized in that, described lobe (101) is provided with along the axially extended described growth passage (2) of lobe (101) and the described growth passage (2) along the extension of lobe (101) radial direction.
9. the artificial skeletal grain according to claim 1 or 2 or 3 or 4, it is characterized in that, the quantity of described lobe (101) is six, wherein four lobe (101) are at grade in cross distribution, and two other lobe (101) is perpendicular to above-mentioned plane and coaxially arrange and lay respectively at the both sides of above-mentioned plane.
10. the artificial skeletal grain according to Claims 2 or 3 or 4, is characterized in that, the internal diameter respectively growing passage (2) is identical or different or incomplete same.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511024549.5A CN105476732A (en) | 2015-12-31 | 2015-12-31 | Artificial bone grain |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511024549.5A CN105476732A (en) | 2015-12-31 | 2015-12-31 | Artificial bone grain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105476732A true CN105476732A (en) | 2016-04-13 |
Family
ID=55664258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201511024549.5A Pending CN105476732A (en) | 2015-12-31 | 2015-12-31 | Artificial bone grain |
Country Status (1)
| Country | Link |
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| CN (1) | CN105476732A (en) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030055511A1 (en) * | 2000-03-03 | 2003-03-20 | Schryver Jeffrey E. | Shaped particle comprised of bone material and method of making the particle |
| WO2004098457A1 (en) * | 2003-04-30 | 2004-11-18 | Therics, Inc. | Bone void filler and method of manufacture |
| CN102548509A (en) * | 2009-08-19 | 2012-07-04 | 史密夫和内修有限公司 | Porous implant structures |
| CN102846408A (en) * | 2011-06-29 | 2013-01-02 | 北京爱康宜诚医疗器材股份有限公司 | Bone grafting filler metal particle body |
| CN103445883A (en) * | 2012-06-04 | 2013-12-18 | 合硕生技股份有限公司 | Medical hollow-out rack implant |
| DE102012213246A1 (en) * | 2012-07-27 | 2014-01-30 | Aesculap Ag | Support unit in oligopodus form useful as tissue repair material e.g. bone substitute for treating tissue defects e.g. bone defects, and filling bone cavities |
| CN205434003U (en) * | 2015-12-31 | 2016-08-10 | 温州康诺克医疗器械有限公司 | Artifical bone grain |
| CN106137462A (en) * | 2015-05-13 | 2016-11-23 | 贺利氏医疗有限公司 | Graininess heterogeneity bone alternate material and the method manufacturing free forming porous body |
-
2015
- 2015-12-31 CN CN201511024549.5A patent/CN105476732A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030055511A1 (en) * | 2000-03-03 | 2003-03-20 | Schryver Jeffrey E. | Shaped particle comprised of bone material and method of making the particle |
| WO2004098457A1 (en) * | 2003-04-30 | 2004-11-18 | Therics, Inc. | Bone void filler and method of manufacture |
| CN102548509A (en) * | 2009-08-19 | 2012-07-04 | 史密夫和内修有限公司 | Porous implant structures |
| CN102846408A (en) * | 2011-06-29 | 2013-01-02 | 北京爱康宜诚医疗器材股份有限公司 | Bone grafting filler metal particle body |
| CN103445883A (en) * | 2012-06-04 | 2013-12-18 | 合硕生技股份有限公司 | Medical hollow-out rack implant |
| DE102012213246A1 (en) * | 2012-07-27 | 2014-01-30 | Aesculap Ag | Support unit in oligopodus form useful as tissue repair material e.g. bone substitute for treating tissue defects e.g. bone defects, and filling bone cavities |
| CN106137462A (en) * | 2015-05-13 | 2016-11-23 | 贺利氏医疗有限公司 | Graininess heterogeneity bone alternate material and the method manufacturing free forming porous body |
| CN205434003U (en) * | 2015-12-31 | 2016-08-10 | 温州康诺克医疗器械有限公司 | Artifical bone grain |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160413 |
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| RJ01 | Rejection of invention patent application after publication |