CN105456855A - Preparation for treating infantile anorexia and preparing method of preparation - Google Patents

Preparation for treating infantile anorexia and preparing method of preparation Download PDF

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CN105456855A
CN105456855A CN201510920619.9A CN201510920619A CN105456855A CN 105456855 A CN105456855 A CN 105456855A CN 201510920619 A CN201510920619 A CN 201510920619A CN 105456855 A CN105456855 A CN 105456855A
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parts
preparation
water
crude drug
little fire
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998—Hordeum (barley)
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    • A61K36/904—Stemonaceae (Stemona family), e.g. croomia
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    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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Abstract

The invention discloses a preparation for treating infantile anorexia. The preparation is mainly prepared from the following active pharmaceutical ingredients in parts by mass: 3 to 7 parts of schisandra chinensis, 6 to 12 parts of snowcreeper porana herb, 8 to 13 parts of barley, 5 to 9 parts of negundo chastetree fruit, 7 to 13 parts of betel pepper leaf, 3 to 7 parts of radix stemonae, 6 to 10 parts of English walnut branchlet, 4 to 9 parts of prinsepia utilis royle, 5 to 10 parts of roasted rhizoma atractylodis, 7 to 12 parts of humulus lupulus, 6 to 11 parts of spiraea japonica, 9 to 13 parts of Japanese farfugium herb, 8 to 12 parts of bilobate grewia, 5 to 13 parts of root of axillaryflower twistedstalk and 7 to 11 parts of soybean black spermoderm. A prepared product is a traditional Chinese medicine preparation, is safe, and does not have obvious toxic or side effects. The preparation is obtained through the development according to traditional Chinese medicine principles, and has the efficacies of strengthening the spleen and stomach, promoting digestion to stop stagnation and the like. The preparation has the advantages that the taking is convenient; the curative effect is obvious; and the cost is low.

Description

For curing preparation and the method for making of children's's inappetence
Technical field
The present invention relates to traditional Chinese medicine field, particularly relating to a kind of preparation for curing children's's inappetence and method for making.
Background technology
Infantile anorexia refers to long-term loss of appetite or disappearance, is reduced to cardinal symptom with appetite, and be a kind of chronic digestible dysfunction syndrome, be usual diseases of childhood, frequently-occurring disease, within 1 ~ 6 years old, children's is common, and has ascendant trend year by year.Severe patient can cause malnutrition, anemia, rickets and hypoimmunity, occurs recurrent respiratory tract infection, and also having impact in various degree to upgrowth and development of children, nutritional status and intelligent development, is the problem that the current head of a family extremely pays close attention to.From the traditional Chinese medical science, anorexia children's is divided into incoordination between the spleen and stomach, deficiency of spleen-QI and stomach-QI, deficiency of stomach-Yin 3 type by the traditional Chinese medical science, treatment on activating the spleen stomach function regulating, invigorating the spleen and benefiting QI, stomach reinforcing yin nourishing for principle.
Publication No. CN105012676A(application number 201510516723.1) Chinese patent literature disclose a kind of Chinese medicine for the treatment of children's's inappetence, Bai Tongcao 10 ~ 14 parts, Flos Inulae 12 ~ 16 parts, Semen Arecae Prepareta 8 ~ 12 parts, 12 ~ 16 parts, Herba Albiziae, Radix Rosae Normalis 8 ~ 12 parts, 12 ~ 16 parts, green tangerine leaf, Cortex Acanthopancis 8 ~ 12 parts, Flos Caryophylli 14 ~ 18 parts, Radix Ophiopogonis 8 ~ 12 parts, door, Semen Hoveniae (Fructus Hoveniae) 12 ~ 16 parts, Radix Morindae Officinalis 8 ~ 12 parts, Echinacea 12 ~ 16 parts, Semen Raphani 8 ~ 12 parts, Semen Canavaliae 12 ~ 16 parts, Radix Rhodiolae 8 ~ 12 parts, Caulis Sargentodoxae 12 ~ 16 parts, Folium Et Cacumen Murrayae 8 ~ 12 parts, Flos Caryophylli 12 ~ 16 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 8 ~ 12 parts, Actinolitum 12 ~ 16 parts, spirulina 8 ~ 12 parts, Rhizoma et radix valerianae 12 ~ 16 parts, Fructus Rosae Normalis 8 ~ 12 parts.Publication No. CN104547552A(application number 201510029179.8) Chinese patent literature disclose a kind of Chinese medicine for the treatment of infantile anorexia, this Chinese medicine is made up of Radix Adenophorae (Radix Glehniae), Massa Medicata Fermentata, Rhizoma Dioscoreae, Radix Platycodonis, Radix Codonopsis, Endothelium Corneum Gigeriae Galli, Poria, Pericarpium Citri Reticulatae, the Radix Paeoniae Alba, Rhizoma Polygonati, Fructus Mume, Radix Glycyrrhizae.Publication No. CN103721068A(application number 201410026148.2) Chinese patent literature disclose a kind of medicament for the treatment of infantile anorexia, be made up of crude drug Herba basellae rubrae, Herba Blumeae clarkei, Flos Gomphrenae, Radix Phyllagathis fordii, Impatiens leptocaulon Hook.f., Herba Reineckeae Carneae, Caulis et Folium Crotalariae Assamicae, Herba Orchidis Latifoliae and Rhizoma Belamcandae.
Children anorexia not only directly affects growth promoter, and causes resistance to decline, and becomes the puzzlement of parents, therefore, obtains a kind of traditional Chinese medical science formula with the treatment children's inappetence of good result according to clinical empirical summary for many years.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of prepare simple, take safe preparation and method for making for curing children's's inappetence.
Technical scheme of the present invention is:
For curing the preparation of children's's inappetence, being prepared from primarily of following bulk drugs, being mass parts: Fructus Schisandrae Chinensis 3-7, Radix seu Herba Poranae Racemosae 6-12, Fructus Hordei Vulgaris 8-13, Fructus Viticis Negundo 5-9 Folium piperis betlis 7-13, Radix Stemonae 3-7, Ramulus Juglandis 6-10, Folium Prinsepiae Utilis 4-9, Rhizoma Atractylodis (parched) 5-10, Flos lupuli (Flos Humuli Lupuli) 7-12, Ramulus Et folium Spiraeae Acuminatae 6-11, Herba Farfugii japonici 9-13, Radix grewiae bilobae 8-12, bamboo grove clouds 5-13, Glycine max (L.) Merr. 7-11.
In preferred scheme, Fructus Schisandrae Chinensis 4-6, Radix seu Herba Poranae Racemosae 8-10, Fructus Hordei Vulgaris 9-12, Fructus Viticis Negundo 6-8 ， Folium piperis betlis 9-11, Radix Stemonae 4-6, Ramulus Juglandis 7-9, Folium Prinsepiae Utilis 5-8, Rhizoma Atractylodis (parched) 6-9, Flos lupuli (Flos Humuli Lupuli) 9-10, Ramulus Et folium Spiraeae Acuminatae 7-10, Herba Farfugii japonici 10-12, Radix grewiae bilobae 9-11, bamboo grove clouds 7-11, Glycine max (L.) Merr. 8-10.
Be more preferably, Fructus Schisandrae Chinensis 5, Radix seu Herba Poranae Racemosae 9, Fructus Hordei Vulgaris 10.5, Fructus Viticis Negundo 7 ， Folium piperis betlis 10, the Radix Stemonae 5, Ramulus Juglandis 8, Folium Prinsepiae Utilis 6.5, Rhizoma Atractylodis (parched) 7.5, Flos lupuli (Flos Humuli Lupuli) 9.5, Ramulus Et folium Spiraeae Acuminatae 8.5, Herba Farfugii japonici 11, Radix grewiae bilobae 10, bamboo grove clouds 9, Glycine max (L.) Merr. 9.
The preparation method of the powder of the described preparation for curing children's's inappetence, step is as follows:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Ramulus Juglandis, Folium Prinsepiae Utilis, Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, add decocting in water together with step (1) (3) made crude drug, big fire is boiled rear little fire and is decocted 25-40 minute (preferred, 30-35 minute decocted by little fire; Be more preferably, little fire decocts 32 minutes), collecting by filtration filtrate, the water that filtering residue adds equivalent boils again, and big fire is boiled rear little fire and decocted 20-30 minute (preferred, 22-28 minute decocted by little fire; Be more preferably, little fire decocts 25 minutes), filter, collect filtrate, merge twice gained filtrate, concentrated, lyophilization is pulverized and is made medicated powder;
(5) Fructus Schisandrae Chinensis, Rhizoma Atractylodis (parched) and Flos lupuli (Flos Humuli Lupuli) were pulverized 300 mesh sieves, and mixed with step (2) made medicated powder, then mix with step (4) made medicated powder, sterilizing, obtains powder.
The preparation method of the described preparation powder for curing children's's inappetence, the 7-9 that step (4) amount of water is boiled crude drug quality is (preferred, amount of water is 8 times of boiled crude drug quality) doubly.
The preparation method of the soft extract of the described preparation for curing children's's inappetence, step is as follows:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Ramulus Juglandis, Folium Prinsepiae Utilis, Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, add decocting in water together with step (1) (3) made crude drug, amount of water is 8 times of boiled crude drug quality, and big fire is boiled rear little fire and decocted 25-40 minute (preferred, 30-35 minute decocted by little fire; Be more preferably, little fire decocts 32 minutes), collecting by filtration filtrate, the water that filtering residue adds equivalent boils again, and big fire is boiled rear little fire and decocted 20-30 minute (preferred, 22-28 minute decocted by little fire; Be more preferably, little fire decocts 25 minutes), filter, collect filtrate, merge twice gained filtrate;
(5) Fructus Schisandrae Chinensis, Rhizoma Atractylodis (parched) and Flos lupuli (Flos Humuli Lupuli) are pulverized and sieved, mix with step (2) made medicated powder, then mix with step (4) made filtrate, heating is concentrated, adds refined honey, is boiled into clear paste, sterilizing, obtain soft extract.
The preparation method of the described preparation soft extract for curing children's's inappetence, step (5) was pulverized 90-150 mesh sieve and (preferably, was pulverized 100-140 mesh sieve; Be more preferably, pulverized 120 mesh sieves).
The preparation method of the decoction of the described preparation for curing children's's inappetence, step is as follows:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Fructus Schisandrae Chinensis, Ramulus Juglandis, Folium Prinsepiae Utilis, Rhizoma Atractylodis (parched), Flos lupuli (Flos Humuli Lupuli), Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, together pulverize with step (1) (3) made crude drug, load in penetrating bag together with step (2) made medicated powder again and add decocting in water, amount of water is that the 6-8 of total raw material medicine quality is doubly (preferred, amount of water is 7 times of total raw material medicine quality), big fire turns a little fire and decocts 30-44 minute (preferred, 34-40 minute decocted by little fire after boiling; Be more preferably, little fire decocts 37 minutes), filter, collect filtrate, the water that filtering residue adds equivalent boils again, and big fire is boiled rear little fire and decocted, and filters, and collects filtrate, merges twice and decocts gained filtrate, mix thoroughly, sterilizing, obtain decoction with sucrose.
The preparation method of the described preparation decoction for curing children's's inappetence, step (4) big fire is boiled rear little fire and is decocted 20-30 minute (preferred, 22-28 minute decocted by little fire; Be more preferably, little fire decocts 25 minutes).
The preparation method of the chewable tablet of the described preparation for curing children's's inappetence, step is as follows:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Ramulus Juglandis, Folium Prinsepiae Utilis, Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, decocting in water is added together with step (1) (3) made crude drug, amount of water is 8 times of boiled crude drug quality, big fire is boiled rear little fire and is decocted, collecting by filtration filtrate, the water that filtering residue adds equivalent boils again, and big fire is boiled rear little fire and decocted 20-30 minute (preferred, 22-28 minute decocted by little fire; Be more preferably, little fire decocts 25 minutes), filter, collect filtrate, merge twice gained filtrate;
(5) Fructus Schisandrae Chinensis, Rhizoma Atractylodis (parched) and Flos lupuli (Flos Humuli Lupuli) were pulverized 300 mesh sieves, mix with step (2) made medicated powder, join in step (4) made filtrate, drying and crushing makes medicated powder, add the mixing of lactose, aspartame, citric acid and mannitol, add ethanol soft material again, granulate, dry, granulate, add Pulvis Talci tabletting, sterilizing, obtain chewable tablet.
The preparation method of the described preparation chewable tablet for curing children's's inappetence, step (4) big fire is boiled rear little fire and is decocted 25-40 minute (preferred, 30-35 minute decocted by little fire; Be more preferably, little fire decocts 32 minutes).
Preparation recipe safety for curing children's's inappetence provided by the invention, preparation is simple.In addition, excellent results of the present invention also shows:
1, products made thereby of the present invention is Chinese medicine preparation, and safety is without obvious toxic-side effects;
2, this prescription obtains according to the development of Chinese medicine principle, has invigorating the spleen and regulating the stomach, helps digestion and stop the effects such as stagnant;
3, the made dosage form taking convenience of the present invention, evident in efficacy, cost is low.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Fructus Schisandrae Chinensis: base is former: be the fruit of Drymotaenium miyoshianum (Mak.) Mak. kind of plant Fructus Schisandrae Chinensis.Nature and flavor: sour, sweet, temperature.Gui Jing: return lung, the heart, kidney channel.Function cures mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Radix seu Herba Poranae Racemosae: base is former: be root or the herb of convolvulaceous plant buccae rattan.Nature and flavor: warm in nature, acrid in the mouth.Function cures mainly: removing blood stasis, circulation of qi promoting, detumescence poison.
Fructus Hordei Vulgaris: base is former: be the fruit of grass Fructus Hordei Vulgaris.Nature and flavor: Gan Xian are cool.Gui Jing: enter spleen, stomach two warp.Function cures mainly: stomach function regulating, wide intestinal, diuretic.Control dyspepsia to have loose bowels, urine leaching pain, edema, burn.
Fructus Viticis Negundo: base is former: be the fruit of Verbenaceae five-leaved chaste tree.Nature and flavor: arduous, temperature.Function cures mainly: dispel the wind, expectorant, circulation of qi promoting, pain relieving.Cure cold, cough, asthma, migratory arthralgia, malaria, stomachache, hernia, anal fistula.
Folium piperis betlis: base is former: be the leaf of Piperaceae Zhi Wu Spica piperis betlis.Nature and flavor: pungent, temperature.Function cures mainly: dispeiling pathogenic wind and removing dampness, killing parasites for relieving itching.Control cough due to wind and cold, stomachache, pathogenic wind-toxic beriberi, edema during pregnancy, mange, eczema, tinea pedis, scald.
The Radix Stemonae: base is former: be the tuber of Stemonaceae plant Radix stemonae japonicae, Radix Stemonae or radix stemonae tuberosae etc.Nature and flavor: sweetness and bitterness, tepor.Gui Jing: enter lung meridian.Function cures mainly: gentle lung qi, cough-relieving, parasite killing.Control cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma, ascarid, enterobiasis, skin scabies, eczema.
Ramulus Juglandis: base is former: be the twig of juglandaceae plant Semen Juglandis.Nature and flavor: bitter, puckery, property is put down.Function cures mainly: killing parasites for relieving itching, detoxicating and resolving stagnation of pathogens.Main scabies, scrofula, lump.
Folium Prinsepiae Utilis: base is former: be the leaf of rosaceous plant Folium Prinsepiae Utilis.Nature and flavor: cold nature, bitter in the mouth.Function cures mainly: counteracting toxic substances, blood stasis dispelling.Control skin sore, fracture.
Rhizoma Atractylodis (parched): base is former: be the rhizome of feverfew RHIZOMA ATRACTYLODIS IANCEAE or Atractylis chinensis etc.Get Rhizoma Atractylodis sheet, spray moistening with rice-washed water, put in pot to fry with slow fire and take out to micro-yellow, section, is drying to obtain.Nature and flavor: pungent, bitter, temperature.Gui Jing: return spleen, stomach, Liver Channel.Function cures mainly: drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.
Flos lupuli (Flos Humuli Lupuli): base is former: be the female inflorescence of moraceae plants Flos lupuli (Flos Humuli Lupuli).Nature and flavor: bitter are flat.Function cures mainly: invigorating the stomach and promoting digestion, anti-consumptive disease, diuresis of calming the nerves.For inappetence, abdominal distention, pulmonary tuberculosis, pleuritis, insomnia, hysteria, edema, cystitis.
Ramulus Et folium Spiraeae Acuminatae: base is former: be the Herb of the narrow leaf Ramulus et Folium Spiraeae Salicifolia of rosaceous plant.Nature and flavor: bitter are flat.Function cures mainly: stimulate the menstrual flow, relieving constipation, diuresis.Cure mainly amenorrhea, menoxenia, constipation abdominal distention, dysuria.
Herba Farfugii japonici: base is former: be the Herb of feverfew Farfugium japonicum.Nature and flavor: pungent, temperature, nontoxic.Function cures mainly: heat clearing away, and removing toxic substances, invigorates blood circulation.Control anemopyretic cold, laryngopharynx swelling and pain, carbuncle, furuncle, scrofula, traumatic injury.
Radix grewiae bilobae: base is former: be root, stem, the leaf of Tiliaceae plant bilobed grewia.Nature and flavor: sweet, bitter, temperature.Gui Jing: liver, spleen, stomach warp.Function cures mainly: invigorating the spleen and benefiting QI, expelling wind and removing dampness, treating spontaneous emission and leukorrhagia.Main insufficiency of the spleen lack of appetite, proctoptosis of a specified duration, infantile malnutrition, ascariasis, rheumatic arthralgia, seminal emission, metrorrhagia, leukorrhagia, uterine prolapse.
Bamboo grove clouds: base is former: for the precious tongued bell of liliaceous plant is careless or the root and rhizome of disporum bodinieri Wang et Tang.Nature and flavor: sweet in the mouth, light, property is put down.Function cures mainly: nourishing the lung to arrest cough, and strong gland helps digestion, relaxing muscles and tendons and activating QI and blood in the collateral, heat-clearing and toxic substances removing.Main cough due to lung-heat, pulmonary tuberculosis is spat blood, food stagnation distension, rheumatic arthralgia, lumbago and skelalgia, fracture, burn.
Glycine max (L.) Merr.: base is former: the seed (Semen sojae atricolor) for the seed coat black of legume soybean steams net for catching birds or fish and processes.Nature and flavor: sweet, temperature.Gui Jing: spleen, stomach warp.Function cures mainly: expelling wind and removing dampness, invigorating the spleen and benefiting QI.Main arthralgia chiefly caused by damp pathogen, joint rash pain, insufficiency of the spleen lack of appetite, gastral cavilty harm is vexed, scrotum pruritus due to damp pathogen.
Embodiment 1, for curing the preparation of children's's inappetence, is prepared from (every part of 10g) primarily of following bulk drugs: Fructus Schisandrae Chinensis 3 parts, Radix seu Herba Poranae Racemosae 6 parts, Fructus Hordei Vulgaris 8 parts, Fructus Viticis Negundo 5 Fen ， Folium piperis betlis 7 parts, the Radix Stemonae 3 parts, Ramulus Juglandis 6 parts, Folium Prinsepiae Utilis 4 parts, Rhizoma Atractylodis (parched) 5 parts, Flos lupuli (Flos Humuli Lupuli) 7 parts, Ramulus Et folium Spiraeae Acuminatae 6 parts, Herba Farfugii japonici 9 parts, Radix grewiae bilobae 8 parts, bamboo grove clouds 5 parts, Glycine max (L.) Merr. 7 parts.
The preparation method of the above-mentioned preparation powder for curing children's's inappetence is:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Ramulus Juglandis, Folium Prinsepiae Utilis, Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, add decocting in water together with step (1) (3) made crude drug, amount of water is 8 times of boiled crude drug quality, and big fire is boiled rear little fire and decocted 32 minutes, collecting by filtration filtrate, the water that filtering residue adds equivalent boils again, and big fire is boiled rear little fire and decocted 25 minutes, filters, collect filtrate, merge twice gained filtrate, concentrated, lyophilization is pulverized and is made medicated powder;
(5) Fructus Schisandrae Chinensis, Rhizoma Atractylodis (parched) and Flos lupuli (Flos Humuli Lupuli) were pulverized 300 mesh sieves, and mixed with step (2) made medicated powder, then mix with step (4) made medicated powder, sterilizing, obtains powder.
Embodiment 2, for curing the preparation of children's's inappetence, is prepared from (every part of 10g) primarily of following bulk drugs: Fructus Schisandrae Chinensis 7 parts, Radix seu Herba Poranae Racemosae 12 parts, Fructus Hordei Vulgaris 13 parts, Fructus Viticis Negundo 9 Fen ， Folium piperis betlis 13 parts, the Radix Stemonae 7 parts, Ramulus Juglandis 10 parts, Folium Prinsepiae Utilis 9 parts, Rhizoma Atractylodis (parched) 10 parts, Flos lupuli (Flos Humuli Lupuli) 12 parts, Ramulus Et folium Spiraeae Acuminatae 11 parts, Herba Farfugii japonici 13 parts, Radix grewiae bilobae 12 parts, bamboo grove clouds 13 parts, Glycine max (L.) Merr. 11 parts.
For curing the preparation method of the preparation soft extract of children's's inappetence be:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Ramulus Juglandis, Folium Prinsepiae Utilis, Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, decocting in water is added together with step (1) (3) made crude drug, amount of water is 8 times of boiled crude drug quality, big fire is boiled rear little fire and is decocted 32 minutes, collecting by filtration filtrate, and the water that filtering residue adds equivalent boils again, big fire is boiled rear little fire and is decocted 25 minutes, filter, collect filtrate, merge twice gained filtrate;
(5) Fructus Schisandrae Chinensis, Rhizoma Atractylodis (parched) and Flos lupuli (Flos Humuli Lupuli) were pulverized 120 mesh sieves, and mixed with step (2) made medicated powder, then mix with step (4) made filtrate, heating is concentrated, adds refined honey, is boiled into clear paste, sterilizing, obtain soft extract.
Model case: xxx, female, 3 years old.Like at ordinary times eating popsicle cold drink, eating and drinking without temperance, occur inappetence afterwards, lose weight, spirit is not good enough, nearly one week anorexia, and occur the cold symptoms such as cough nasal obstruction, examination in hospital, light red tongue, in vain, deep-slow pulse, abdominal distention, is diagnosed as inappetence to tongue.
Take the present embodiment gained for curing the preparation soft extract of children's's inappetence, every day 2 times, each 4-10ml, warm boiled water, 7 days courses for the treatment of.After taking a course for the treatment of, appetite strengthens, and appetite increases, and well, after taking two courses for the treatment of, appetite recovers normal to spirit, and body weight increases, and well, infant is fully recovered for complexion and spirit.
Embodiment 3, for curing the preparation of children's's inappetence, is prepared from (every part of 10g) primarily of following bulk drugs: Fructus Schisandrae Chinensis 4 parts, Radix seu Herba Poranae Racemosae 8 parts, Fructus Hordei Vulgaris 9 parts, Fructus Viticis Negundo 6 Fen ， Folium piperis betlis 9 parts, the Radix Stemonae 4 parts, Ramulus Juglandis 7 parts, Folium Prinsepiae Utilis 5 parts, Rhizoma Atractylodis (parched) 6 parts, Flos lupuli (Flos Humuli Lupuli) 9 parts, Ramulus Et folium Spiraeae Acuminatae 7 parts, Herba Farfugii japonici 10 parts, Radix grewiae bilobae 9 parts, bamboo grove clouds 7 parts, Glycine max (L.) Merr. 8 parts.
For curing the preparation method of the preparation decoction of children's's inappetence be:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Fructus Schisandrae Chinensis, Ramulus Juglandis, Folium Prinsepiae Utilis, Rhizoma Atractylodis (parched), Flos lupuli (Flos Humuli Lupuli), Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, together pulverize with step (1) (3) made crude drug, load in penetrating bag together with step (2) made medicated powder again and add decocting in water, amount of water is 7 times of total raw material medicine quality, big fire turns little fire after boiling and decocts 37 minutes, filter, collect filtrate, the water that filtering residue adds equivalent boils 25 minutes again, and big fire is boiled rear little fire and decocted, filter, collect filtrate, merge twice and decoct gained filtrate, mix thoroughly with sucrose, sterilizing, obtains decoction.
Model case: xxx, man, 6 years old.Usual sock, when having a meal, appetite is low, and appetite is few, day by day becomes thin, recently anorexia, stomachache, uneasy sleeping at night, deficiency of QI with disinclination to talk, hands and feet being not warm, large loose stool, examination in hospital, light red tongue, white and thin fur, and moderate pulse is slightly thin, and other are diagnosed as inappetence without malaise symptoms.
Taking the present embodiment gained for curing the preparation decoction of children's's inappetence, adopting every day 2 times, each 30-60ml, warm, 7 days courses for the treatment of.After taking a course for the treatment of, appetite is cumulative, and stomachache is eliminated, and sleep is good, and the palm of the hand turns temperature, and stool is normal, and after taking two courses for the treatment of, appetite recovers normal, and other malaise symptoms disappear all substantially, continue to take a course for the treatment of, and infant body weight obviously increases, recovery from illness.
Embodiment 4, for curing the preparation of children's's inappetence, is prepared from (every part of 10g) primarily of following bulk drugs: Fructus Schisandrae Chinensis 6 parts, Radix seu Herba Poranae Racemosae 10 parts, Fructus Hordei Vulgaris 12 parts, Fructus Viticis Negundo 8 Fen ， Folium piperis betlis 11 parts, the Radix Stemonae 6 parts, Ramulus Juglandis 9 parts, Folium Prinsepiae Utilis 8 parts, Rhizoma Atractylodis (parched) 9 parts, Flos lupuli (Flos Humuli Lupuli) 10 parts, Ramulus Et folium Spiraeae Acuminatae 10 parts, Herba Farfugii japonici 12 parts, Radix grewiae bilobae 11 parts, bamboo grove clouds 11 parts, Glycine max (L.) Merr. 10 parts.
For curing the preparation method of the preparation chewable tablet of children's's inappetence be:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Ramulus Juglandis, Folium Prinsepiae Utilis, Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, decocting in water is added together with step (1) (3) made crude drug, amount of water is 8 times of boiled crude drug quality, big fire is boiled rear little fire and is decocted, collecting by filtration filtrate, and the water that filtering residue adds equivalent boils 32 minutes again, big fire is boiled rear little fire and is decocted 25 minutes, filter, collect filtrate, merge twice gained filtrate;
(5) Fructus Schisandrae Chinensis, Rhizoma Atractylodis (parched) and Flos lupuli (Flos Humuli Lupuli) were pulverized 300 mesh sieves, mix with step (2) made medicated powder, join in step (4) made filtrate, drying and crushing makes medicated powder, add the mixing of lactose, aspartame, citric acid and mannitol, add ethanol soft material again, granulate, dry, granulate, add Pulvis Talci tabletting, sterilizing, obtain chewable tablet.
Model case: xxx, man, 4 years old.Eating meat, vegetarian diet is few, and once nausea and vomiting, recently lack of appetite after meal before two weeks, poor appetite, indistinctly, indigestion, spiritlessness and weakness, feverish palms, defecates partially dry, examination in hospital, and red tongue, white and thin fur, thready and rolling pulse, is diagnosed as inappetence in normal stomachache after meal.
Taking the present embodiment gained for curing the preparation chewable tablet of children's's inappetence, adopting every day 2 times, each 2, directly chewing, 7 days courses for the treatment of.After taking 3 days, appetite improves, and stomachache disappears, and after taking a course for the treatment of, appetite increase, feverish palms subtracts, and spirit is good, free movement of the bowels, and after taking two courses for the treatment of, appetite was recovered as the past, and other are without malaise symptoms, and infant is fully recovered.
Embodiment 5, for curing the preparation of children's's inappetence, is prepared from (every part of 10g) primarily of following bulk drugs: Fructus Schisandrae Chinensis 5 parts, Radix seu Herba Poranae Racemosae 9 parts, Fructus Hordei Vulgaris 10.5 parts, Fructus Viticis Negundo 7 Fen ， Folium piperis betlis 10 parts, the Radix Stemonae 5 parts, Ramulus Juglandis 8 parts, Folium Prinsepiae Utilis 6.5 parts, Rhizoma Atractylodis (parched) 7.5 parts, Flos lupuli (Flos Humuli Lupuli) 9.5 parts, Ramulus Et folium Spiraeae Acuminatae 8.5 parts, Herba Farfugii japonici 11 parts, Radix grewiae bilobae 10 parts, bamboo grove clouds 9 parts, Glycine max (L.) Merr. 9 parts.
For curing the preparation method of the preparation powder of children's's inappetence be:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Ramulus Juglandis, Folium Prinsepiae Utilis, Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, add decocting in water together with step (1) (3) made crude drug, amount of water is 8 times of boiled crude drug quality, and big fire is boiled rear little fire and decocted 32 minutes, collecting by filtration filtrate, the water that filtering residue adds equivalent boils again, and big fire is boiled rear little fire and decocted 25 minutes, filters, collect filtrate, merge twice gained filtrate, concentrated, lyophilization is pulverized and is made medicated powder;
(5) Fructus Schisandrae Chinensis, Rhizoma Atractylodis (parched) and Flos lupuli (Flos Humuli Lupuli) were pulverized 300 mesh sieves, and mixed with step (2) made medicated powder, then mix with step (4) made medicated powder, sterilizing, obtains powder.
Test example 1 gained of the present invention is for curing the clinical practice of the preparation (embodiment 5) of children's's inappetence:
In March ,-2014 in March, 2013, filter out at 4 hospital-based outpatient pediatic clinics the infant that 418 examples are diagnosed as children's's inappetence, wherein female 185 example, male 233 example, age 1-6 year, the mean age (2.6 ± 1.8) year, the course of disease 7 days-2 months.Inclusion criteria: 1. appetite reduces, appetite reduces; 2. stomachache indistinctly, and cold type of pain is uncomfortable, indigestion; 3. abdominal pain and distension, spiritlessness and weakness, deficiency of QI with disinclination to talk, hands and feet being not warm, large loose stool, part infant nausea and vomiting.The inappetence that eliminating rickets and digestive system disease, helminth disease etc. cause.
Patient is divided into two groups at random, experimental group 265 example and matched group 153 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (P > 0.05), there is comparability.Experimental group takes products obtained therefrom of the present invention, and every day takes twice, and each 5-10g(adjusts to some extent depending on concrete condition), 7 days courses for the treatment of, treat two courses for the treatment of.Matched group takes other medicine conventional medication such as (helping digestion of baby appetizing) granule, ZHIERLING soft extract, infantile anorexia granules.Treatments period carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect situation criterion: effective: the cardinal symptom such as anorexia, monophagia, abdominal distention, stomachache, diarrhoea, constipation disappears, appetite and appetite recover normal; Effective: clinical cardinal symptom takes a turn for the better, appetite takes a turn for the better, and appetite increases before comparatively treating but do not reach normal child's appetite of the same age; Invalid: treatment before and after, cardinal symptom and appetite appetite all unchanged.Result is as shown in table 1.
Table 1 liang group infant therapeutic outcome (example/%)
Through treatment, two groups of therapeutic outcomes are as shown in table 1, experimental group infant, effective 201 examples, effective 58 examples, experimental group treatment total effective rate is 97.7%, in matched group, effective 77 examples, effective 54 examples, treatment of control group total effective rate is 85.6%, more known, the therapeutic effect comparatively matched group good (P < 0.05) of experimental group.
In prescription of the present invention, Fructus Schisandrae Chinensis can supplementing QI for promoting the production of body fluid, Radix seu Herba Poranae Racemosae can removing blood stasis circulation of qi promoting, Fructus Hordei Vulgaris can stomach function regulating diuretic, Fructus Viticis Negundo can dispel the wind circulation of qi promoting Folium piperis betlis can dispeiling pathogenic wind and removing dampness, and the Radix Stemonae can gentle lung qi, and Ramulus Juglandis can killing parasites for relieving itching, Folium Prinsepiae Utilis can counteracting toxic substances blood stasis dispelling, Rhizoma Atractylodis (parched) can be drying damp and strengthening spleen, and Flos lupuli (Flos Humuli Lupuli) can be calmed the nerves diuresis, and Ramulus Et folium Spiraeae Acuminatae can stimulate the menstrual flow relieving constipation, Herba Farfugii japonici can heat clearing and blood circulation promoting, Radix grewiae bilobae can invigorating the spleen and benefiting QI, and bamboo grove clouds can be good for gland and be helped digestion, and Glycine max (L.) Merr. can expelling wind and removing dampness, all medicines share, and can play invigorating the spleen and regulating the stomach, help digestion and stop the effects such as stagnant.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. for curing the preparation of children's's inappetence, it is characterized in that, being prepared from primarily of following bulk drugs, be mass parts: Fructus Schisandrae Chinensis 3-7, Radix seu Herba Poranae Racemosae 6-12, Fructus Hordei Vulgaris 8-13, Fructus Viticis Negundo 5-9 ， Folium piperis betlis 7-13, Radix Stemonae 3-7, Ramulus Juglandis 6-10, Folium Prinsepiae Utilis 4-9, Rhizoma Atractylodis (parched) 5-10, Flos lupuli (Flos Humuli Lupuli) 7-12, Ramulus Et folium Spiraeae Acuminatae 6-11, Herba Farfugii japonici 9-13, Radix grewiae bilobae 8-12, bamboo grove clouds 5-13, Glycine max (L.) Merr. 7-11.
2. as claimed in claim 1 for curing the preparation of children's's inappetence, it is characterized in that, Fructus Schisandrae Chinensis 4-6, Radix seu Herba Poranae Racemosae 8-10, Fructus Hordei Vulgaris 9-12, Fructus Viticis Negundo 6-8, Folium piperis betlis 9-11, Radix Stemonae 4-6, Ramulus Juglandis 7-9, Folium Prinsepiae Utilis 5-8, Rhizoma Atractylodis (parched) 6-9, Flos lupuli (Flos Humuli Lupuli) 9-10, Ramulus Et folium Spiraeae Acuminatae 7-10, Herba Farfugii japonici 10-12, Radix grewiae bilobae 9-11, bamboo grove clouds 7-11, Glycine max (L.) Merr. 8-10 is (preferred, Fructus Schisandrae Chinensis 5, Radix seu Herba Poranae Racemosae 9, Fructus Hordei Vulgaris 10.5, Fructus Viticis Negundo 7, Folium piperis betlis 10, the Radix Stemonae 5, Ramulus Juglandis 8, Folium Prinsepiae Utilis 6.5, Rhizoma Atractylodis (parched) 7.5, Flos lupuli (Flos Humuli Lupuli) 9.5, Ramulus Et folium Spiraeae Acuminatae 8.5, Herba Farfugii japonici 11, Radix grewiae bilobae 10, bamboo grove clouds 9, Glycine max (L.) Merr. 9).
3. the preparation method of the powder of the preparation for curing children's's inappetence as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Ramulus Juglandis, Folium Prinsepiae Utilis, Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, add decocting in water together with step (1) (3) made crude drug, big fire is boiled rear little fire and is decocted 25-40 minute (preferred, 30-35 minute decocted by little fire; Be more preferably, little fire decocts 32 minutes), collecting by filtration filtrate, the water that filtering residue adds equivalent boils again, and big fire is boiled rear little fire and decocted 20-30 minute (preferred, 22-28 minute decocted by little fire; Be more preferably, little fire decocts 25 minutes), filter, collect filtrate, merge twice gained filtrate, concentrated, lyophilization is pulverized and is made medicated powder;
(5) Fructus Schisandrae Chinensis, Rhizoma Atractylodis (parched) and Flos lupuli (Flos Humuli Lupuli) were pulverized 300 mesh sieves, and mixed with step (2) made medicated powder, then mix with step (4) made medicated powder, sterilizing, obtains powder.
4. as claimed in claim 3 for curing the preparation method of the preparation powder of children's's inappetence, it is characterized in that, the 7-9 that step (4) amount of water is boiled crude drug quality is (preferred, amount of water is 8 times of boiled crude drug quality) doubly.
5. the preparation method of the soft extract of the preparation for curing children's's inappetence as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Ramulus Juglandis, Folium Prinsepiae Utilis, Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, add decocting in water together with step (1) (3) made crude drug, amount of water is 8 times of boiled crude drug quality, and big fire is boiled rear little fire and decocted 25-40 minute (preferred, 30-35 minute decocted by little fire; Be more preferably, little fire decocts 32 minutes), collecting by filtration filtrate, the water that filtering residue adds equivalent boils again, and big fire is boiled rear little fire and decocted 20-30 minute (preferred, 22-28 minute decocted by little fire; Be more preferably, little fire decocts 25 minutes), filter, collect filtrate, merge twice gained filtrate;
(5) Fructus Schisandrae Chinensis, Rhizoma Atractylodis (parched) and Flos lupuli (Flos Humuli Lupuli) are pulverized and sieved, mix with step (2) made medicated powder, then mix with step (4) made filtrate, heating is concentrated, adds refined honey, is boiled into clear paste, sterilizing, obtain soft extract.
6. as claimed in claim 5 for curing the preparation method of the preparation soft extract of children's's inappetence, it is characterized in that, step (5) was pulverized 90-150 mesh sieve and (preferably, was pulverized 100-140 mesh sieve; Be more preferably, pulverized 120 mesh sieves).
7. the preparation method of the decoction of the preparation for curing children's's inappetence as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Fructus Schisandrae Chinensis, Ramulus Juglandis, Folium Prinsepiae Utilis, Rhizoma Atractylodis (parched), Flos lupuli (Flos Humuli Lupuli), Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, together pulverize with step (1) (3) made crude drug, load in penetrating bag together with step (2) made medicated powder again and add decocting in water, amount of water is that the 6-8 of total raw material medicine quality is doubly (preferred, amount of water is 7 times of total raw material medicine quality), big fire turns a little fire and decocts 30-44 minute (preferred, 34-40 minute decocted by little fire after boiling; Be more preferably, little fire decocts 37 minutes), filter, collect filtrate, the water that filtering residue adds equivalent boils again, and big fire is boiled rear little fire and decocted, and filters, and collects filtrate, merges twice and decocts gained filtrate, mix thoroughly, sterilizing, obtain decoction with sucrose.
8. as claimed in claim 7 for curing the preparation method of the preparation decoction of children's's inappetence, it is characterized in that, step (4) big fire is boiled rear little fire and is decocted 20-30 minute (preferred, 22-28 minute decocted by little fire; Be more preferably, little fire decocts 25 minutes).
9. the preparation method of the chewable tablet of the preparation for curing children's's inappetence as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Radix seu Herba Poranae Racemosae, Folium piperis betlis and Herba Farfugii japonici roguing rice-washed water floods 30 minutes, take out, drain the water on surface, be placed in heating in frying pan with Oleum Brassicae campestris, impregnated crude drug is put into frying pan, slow fire heating stir-fries, when frying yellow micro-to crude drug surface, take out, dry in the air cool;
(2) get Fructus Hordei Vulgaris to dry together with Glycine max (L.) Merr., be ground into end, made powder is placed in frying pan, add the Oleum sesami of powder quality 0.2 times, slow fire stir-fry to crude drug surface micro-yellow time, take out, spread out dry in the air cool, obtained medicated powder;
(3) Radix Stemonae and Radix grewiae bilobae are infiltrated, taking-up section or cutting, add Chinese liquor together with Fructus Viticis Negundo and brown sugar is mixed thoroughly, and load in container, be placed in steamer, water proof exhausts to wine, takes out, dry;
(4) by Ramulus Juglandis, Folium Prinsepiae Utilis, Ramulus Et folium Spiraeae Acuminatae and the remove impurity of bamboo grove clouds, decocting in water is added together with step (1) (3) made crude drug, amount of water is 8 times of boiled crude drug quality, big fire is boiled rear little fire and is decocted, collecting by filtration filtrate, the water that filtering residue adds equivalent boils again, and big fire is boiled rear little fire and decocted 20-30 minute (preferred, 22-28 minute decocted by little fire; Be more preferably, little fire decocts 25 minutes), filter, collect filtrate, merge twice gained filtrate;
(5) Fructus Schisandrae Chinensis, Rhizoma Atractylodis (parched) and Flos lupuli (Flos Humuli Lupuli) were pulverized 300 mesh sieves, mix with step (2) made medicated powder, join in step (4) made filtrate, drying and crushing makes medicated powder, add the mixing of lactose, aspartame, citric acid and mannitol, add ethanol soft material again, granulate, dry, granulate, add Pulvis Talci tabletting, sterilizing, obtain chewable tablet.
10. as claimed in claim 9 for curing the preparation method of the preparation chewable tablet of children's's inappetence, it is characterized in that, step (4) big fire is boiled rear little fire and is decocted 25-40 minute (preferred, 30-35 minute decocted by little fire; Be more preferably, little fire decocts 32 minutes).
CN201510920619.9A 2015-12-14 2015-12-14 Preparation for treating infantile anorexia and preparing method of preparation Pending CN105456855A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106236894A (en) * 2016-10-25 2016-12-21 徐俊杰 A kind of Chinese medicinal granule treating infantile dyspepsia

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张秀华等: "厌食冲剂治疗小儿厌食症的临床与实验研究", 《河南中医》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106236894A (en) * 2016-10-25 2016-12-21 徐俊杰 A kind of Chinese medicinal granule treating infantile dyspepsia

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