CN105456786A - Medicine for treating herpes simplex virus infection - Google Patents

Medicine for treating herpes simplex virus infection Download PDF

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CN105456786A
CN105456786A CN201510989126.0A CN201510989126A CN105456786A CN 105456786 A CN105456786 A CN 105456786A CN 201510989126 A CN201510989126 A CN 201510989126A CN 105456786 A CN105456786 A CN 105456786A
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parts
grams
medicine
radix
herpes simplex
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黄全
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483Gleditsia (locust)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
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    • A61K36/88Liliopsida (monocotyledons)
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    • AHUMAN NECESSITIES
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    • A61K9/00Medicinal preparations characterised by special physical form
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Abstract

The invention relates to a medicine for treating herpes simplex virus infection, belongs to the technical field of medicines, and aims at solving the problem of treatment of the herpes simplex virus infection. The medicine is mainly prepared from the following traditional Chinese medicines in parts by weight: 10 parts of mung bean, 20 parts of honeysuckle, 15 parts of dried radix rehmanniae, 15 parts of spina gleditsiae, 15 parts of mulberry leaves, 15 parts of pericarpium citri reticulatae viride, 15 parts of folium isatidis, 15 parts of radix achyranthis bidentatae, 15 parts of radix isatidis, 10 parts of lalang grass rhizome, 10 parts of seaweeds and 7 parts of liquorice. According to the medicine for treating the herpes simplex virus infection, the traditional Chinese medicines capable of clearing the lung, cooling the blood, activating blood circulation, clearing away heat and toxic materials, removing wind and reducing phlegm for treatment are combined, so that an obvious treatment effect is obtained.

Description

The medicine that a kind of simple herpes virus infects
Technical field
The present invention relates to the medicine that a kind of simple herpes virus infects, particularly with the composition of medicine for the treatment of by Chinese herbs, belong to medicine technology field.
Background technology
Herpes simplex infections is the infectious disease that herpes simplex virus (HSV) causes.Human herpes simplex virus is divided into amphitypy, i.e. herpes simplex virus I-type (HSV-I) and herpes simplex virus type II (HSV-II).I type mainly causes the infection of skin, mucosa (oral mucosa) and organ (brain) beyond genitals.II type mainly causes genital area mucocutaneous infections.Virus enters in body through respiratory tract, oral cavity, genital mucosa and damaged skin, dives and occupy in human normal mucosa, blood, saliva and sensory nerve ganglion cell.When Abwehrkraft des Koepers declines, as heating, gastrointestinal dysfunction, menstruation, gestation, focal infection and mood change time, the HSV hidden in body is activated and falls ill.
The infectious disease that herpes simplex virus (HSV) causes.HSV can divide 1 type (HSV-1) and 2 types (HSV-2).Common HSV infects recurrent herpes labialis, skin bleb, acute herpetic mouth gingivitis and acute herpetic keratoconjunctivitis.Rare has acute herpetic nervous system infection as meningitis, encephalitis, myelitis and radiculitis.Neonate and immunologic hypofunction person often show as serious general HSV and infect.The heavy case fatality rate of the herpes simplex encephalitis state of an illness is high, the caused life-long disabilities had.HSV infects very general, and according to the investigation to HSV antibody in crowd, about within 90%10 years old, have HSV antibody in serum of children, adult can reach 100%, and this illustrates that they have lived through HSV and have infected.Western countries, as the U.S. and some Western European countries, the genital herpes that HSV-2 causes, popular as sexually transmitted disease,, can there is generalized dissemination herpes infection and herpes simplex encephalitis in the neonate that the women suffering from genital herpes gives birth to, its case fatality rate is high or leave serious sequela.Some organ transplantations and accept the patient of immunosuppressant and antineoplastic agent treatment, due to immunologic hypofunction, can general herpes generalisatus to infect and even dead.In addition, many data prove, HSV-1 infects may be relevant with lip cancer, and HSV-2 infects then may be relevant with the generation of cervical cancer, and therefore research to HSV and infection thereof and control are all attached great importance in countries in the world.
Primary disease is caused by the herpes simplex virus of DNA viruses.Human herpes simplex virus is divided into amphitypy, i.e. herpes simplex virus I-type (HSV-I) and herpes simplex virus type II (HSV-II).I type mainly causes the infection of skin, mucosa (oral mucosa) and organ (brain) beyond genitals.II type mainly causes genital area mucocutaneous infections.Virus enters in body through respiratory tract, oral cavity, genital mucosa and damaged skin, dives and occupy in human normal mucosa, blood, saliva and sensory nerve ganglion cell.When Abwehrkraft des Koepers declines, as heating, gastrointestinal dysfunction, menstruation, gestation, focal infection and mood change time, the HSV hidden in body is activated and falls ill.
Light-duty patient does not need whole body application antiviral therapy.Iodine deoxidation uracil nucleoside (iodouracil desoxyriboside) Local eye drop treatment herpetic keratoconjunctivitis effect is better, but because of the more unsuitable whole body application of toxicity.Infect and herpes simplex encephalitis patient herpes generalisatus, the intravenous drip of application vidarabine has good effect.Have the intravenous drip of report acycloguanosine, toxicity is low, good effect.In addition general support and symptomatic therapy should be strengthened.Have should to add during secondary bacterial infection and use antibiotic.
Summary of the invention
Infect with the simple herpes virus of Chinese medicine viewpoint analysis, belong to deficiency of YIN-blood, wind is excessive wetly to be held back, warm knot poison, QI and blood resistance numbness and send out this disease, treatment should with liver heat removing, removing heat from blood, invigorate blood circulation, the Chinese medicine combined treatment of heat-clearing and toxic substances removing, dispelling pathogenic wind and eliminating phlegm.
The medicine that a kind of simple herpes virus infects taked technical scheme of dealing with problems combines by each Chinese medicine quality part ratio below: 10 parts, Semen phaseoli radiati, Flos Lonicerae 20 parts, 15 parts, the Radix Rehmanniae, Spina Gleditsiae 15 parts, 15 parts, Folium Mori, 15 parts, Pericarpium Citri Reticulatae Viride, Folium Isatidis 15 parts, Radix Achyranthis Bidentatae 15 parts, Radix Isatidis 15 parts, Rhizoma Imperatae 10 parts, Sargassum 10 parts, 7 parts, Radix Glycyrrhizae.
Property of medicine effect of each Chinese medicine in the medicine that a kind of simple herpes virus of lower surface analysis infects.Semen phaseoli radiati nature and flavor are sweet cool, have effect of heat-clearing and toxic substances removing; Summer perspires many people of hot environment work, and the loss of water liquid is very large, and the electrolyte balance in body is destroyed, and boiling soup to supplement with Semen phaseoli radiati is optimal method.Flos Lonicerae is sweet cold, and the power of heat-clearing and toxic substances removing, antiviral, dissipation carbuncle is strong, is the important medical material for the treatment of pyretic toxicity carbuncle sore, is applicable to treat outer infections abscess of internal organ, sore throat, erysipelas etc. that various hyperactivity of toxic heat causes.Can external application also can decoction.The Radix Rehmanniae have clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, matter profit the effect of letting out is fallen.Effect of Fructus Forsythiae and effect: attribute: bitter, be slightly cold, return lung, the heart, gallbladder meridian.Effect of Spina Gleditsiae: search wind, draws out pus by applying a plaster to the affected part, detumescence, and evacuation of pus, controls carbuncle, sore, leprosy, tinea skin ulcer, placenta retention; There is antitumaous effect.Folium Mori are the dried leaves of moraceae plants Mulberry, and have another name called a Mulberry, Jing Sang, Fructus Mori tree, yellow wood etc., national most area has production more.Folium Mori have good inhibitory anti-virus effect, all right dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, suppressing the hyperactive liver improving eyesight, cooling blood for hemostasis.Pericarpium Citri Reticulatae Viride has the stagnant effect of good soothing the liver dispelling the stagnated QI, removing food stagnancyization, and for costa sternales gastral cavity distending pain, acute mastitis, colic, the treatment of stagnation of QI due to dyspepsia has good effect.Folium Isatidis: bitter, cold; GUIXIN, stomach warp; Effect: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing; Join the army for pathogenic warmth, unconsciousness due to high fever, sends out speckle dermexanthesis, jaundice, hematodiarrhoea, mumps, sore throat, erysipelas, carbuncle.Radix Achyranthis Bidentatae is used for soreness of waist and knee joint, and muscles and bones is unable, amenorrhea and mass in the abdomen, dizziness due to hyperactivity of liver-YANG.Radix Isatidis, also known as indigo-blue, Isatis indigotica Fort (Indigofera tinctoria L, Baphicanthus cusia (nees) Brem. Polygonum tinctorium Ait) root, Radix Clerodenri Cyrtophylli, be a kind of Chinese crude drug, bitter in the mouth, cold; There is heat-clearing and toxic substances removing, effect of the antiviral that dispels the wind, removing heat from blood sore-throat relieving; Be usually used in pestilence seasonal noxious pathogen, heating pharyngalgia, maculae caused by violent heat pathogen.Scolopendra acrid in the mouth, warm in nature, poisonous, enter Liver Channel.The effect of Rhizoma Imperatae and effect: cooling blood for hemostasis, heat-clearing and toxic substances removing; For spitting blood, hematuria, pyretic stranguria, edema, jaundice, dysuria, calentura excessive thirst, gastric heat is vomitted the sound of vomiting, coughs.Effect of Sargassum and effect: Sargassum has another name called gloiopeltis, Nori, Zostera marina, large Herba Artemisiae, extra large root vegetables, zostera marina, and effect of Sargassum is heat clearing away, hard masses softening and resolving, softening the hard mass, expectorant, diuretic detumescent, and thyromegaly is controlled in the effect of Sargassum, the enlargement of item submental lymph nodes.The invigorating middle warmer of Radix Glycyrrhizae QI invigorating, relieving spasm to stop pain; Nourishing the lung to arrest cough; Eliminating fire and detoxication; The mediation property of medicine.
The medicine beneficial effect of the invention that a kind of simple herpes virus infects is: inventor passes through with the simple herpes virus viral infection of Chinese medicine viewpoint analysis, belong to deficiency of YIN-blood, excessive the wetting of wind is held back, warm knot poison, QI and blood hinders numbness and sends out this disease, with liver heat removing, removing heat from blood, invigorate blood circulation, the Chinese medicine combined treatment of heat-clearing and toxic substances removing, dispelling pathogenic wind and eliminating phlegm, obtain obvious therapeutic effect.
Detailed description of the invention
The medicine that a kind of simple herpes virus infects combines by each Chinese medicine quality part ratio below: 10 parts, Semen phaseoli radiati, Flos Lonicerae 20 parts, 15 parts, the Radix Rehmanniae, Spina Gleditsiae 15 parts, 15 parts, Folium Mori, 15 parts, Pericarpium Citri Reticulatae Viride, Folium Isatidis 15 parts, Radix Achyranthis Bidentatae 15 parts, Radix Isatidis 15 parts, Rhizoma Imperatae 10 parts, Sargassum 10 parts, 7 parts, Radix Glycyrrhizae.According to above drug ratio ratio, it is combine by each Chinese medicine quality below that the medicine that a kind of simple herpes virus infects is suitable for a dose drug that a simple herpes virus infected patient takes: 10 grams, Semen phaseoli radiati, Flos Lonicerae 20 grams, 15 grams, the Radix Rehmanniae, Spina Gleditsiae 15 grams, 15 grams, Folium Mori, 15 grams, Pericarpium Citri Reticulatae Viride, Folium Isatidis 15 grams, Radix Achyranthis Bidentatae 15 grams, Radix Isatidis 15 grams, Rhizoma Imperatae 10 grams, Sargassum 10 grams, 7 grams, Radix Glycyrrhizae.Using method: decoct soup and take medicinal liquid orally, abandon medicinal residues, day takes dose, serveing on 15 days is a course for the treatment of, can slow down and slightly subtract dose continue to take, until each transference cure after the course for the treatment of according to the state of an illness.

Claims (2)

1. the medicine that infects of simple herpes virus, is characterized in that combining by each Chinese medicine quality part ratio below: 10 parts, Semen phaseoli radiati, Flos Lonicerae 20 parts, 15 parts, the Radix Rehmanniae, Spina Gleditsiae 15 parts, 15 parts, Folium Mori, 15 parts, Pericarpium Citri Reticulatae Viride, Folium Isatidis 15 parts, Radix Achyranthis Bidentatae 15 parts, Radix Isatidis 15 parts, Rhizoma Imperatae 10 parts, Sargassum 10 parts, 7 parts, Radix Glycyrrhizae.
2. the medicine that infects of a kind of simple herpes virus according to claim 1, is characterized in that: it is combine by each Chinese medicine quality below that the medicine that a kind of simple herpes virus infects is suitable for a dose drug that a simple herpes virus infected patient takes: 10 grams, Semen phaseoli radiati, Flos Lonicerae 20 grams, 15 grams, the Radix Rehmanniae, Spina Gleditsiae 15 grams, 15 grams, Folium Mori, 15 grams, Pericarpium Citri Reticulatae Viride, Folium Isatidis 15 grams, Radix Achyranthis Bidentatae 15 grams, Radix Isatidis 15 grams, Rhizoma Imperatae 10 grams, Sargassum 10 grams, 7 grams, Radix Glycyrrhizae.
CN201510989126.0A 2015-12-28 2015-12-28 Medicine for treating herpes simplex virus infection Pending CN105456786A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105708961A (en) * 2016-04-19 2016-06-29 劳炳凤 Drug for treating herpes zoster virus infection
CN106344826A (en) * 2016-09-28 2017-01-25 防城港思创信息技术有限公司 Preparation method of multi-flavor pill for dispelling wind and expelling evil

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105708961A (en) * 2016-04-19 2016-06-29 劳炳凤 Drug for treating herpes zoster virus infection
CN106344826A (en) * 2016-09-28 2017-01-25 防城港思创信息技术有限公司 Preparation method of multi-flavor pill for dispelling wind and expelling evil

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Application publication date: 20160406