CN105456402A - Medicine for promoting bone fracture recovery - Google Patents

Medicine for promoting bone fracture recovery Download PDF

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Publication number
CN105456402A
CN105456402A CN201511011167.9A CN201511011167A CN105456402A CN 105456402 A CN105456402 A CN 105456402A CN 201511011167 A CN201511011167 A CN 201511011167A CN 105456402 A CN105456402 A CN 105456402A
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parts
medicine
fracture
bone fracture
return
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项阳
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/646Arachnids, e.g. spiders, scorpions, ticks or mites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Insects & Arthropods (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a medicine for promoting bone fracture recovery. The medicine is prepared from the following medicinal materials in parts by weight: 5-10 parts of lotus seed pot, 5-9 parts of flowers of official magnolia, 0.2-0.3 part of borneol, 3-5 parts of frankincense, 16-25 parts of abrus cantoniensis hance, 6-9 parts of ardisia crenata, 3-6 parts of scorpion, 6-12 parts of cortex albiziae, 10-15 parts of poria cocos, 4-7 parts of caesalpinia sappan, 2-5 parts of coptis chinensis, 5-9 parts of Chinese trumpet creeper and 50-60 parts of beewax. The medicine is prepared from pure traditional Chinese medicinal materials, has high safety coefficient, and can be used for accelerating recovery of bone fracture patients and avoiding sequelae of patients.

Description

A kind of medicine promoting fracture recovery
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of medicine that fracture is recovered that promotes.
Background technology
Fracture is that the seriality of bone structure ruptures wholly or in part.Be more common in child and old people, young people also happens occasionally.Patient is often-individual position fracture, and minority is multiple fracture.Through appropriate process in time, most patient can recover original function, and a few patients can leave over sequela in various degree.Present fracture how directly to beat fixing after to rest treatment, but recover comparatively slowly, and because the generation of the situations such as infection can leave sequela in recovery process.
Summary of the invention
The object of this invention is to provide a kind of medicine that fracture is recovered that promotes, use raw material of Chinese medicine preparation, medicine is spread on affected part, fracture recovery can be accelerated, avoid producing sequela.
The present invention is achieved through the following technical solutions:
Promote the medicine recovered of fracturing, be made up of the medicine of following weight portion:
Receptaculum Nelumbinis 5-10, Flos Magnoliae Officinalis 5-9, Borneolum Syntheticum 0.2-0.3, Olibanum 3-5, Herba Abri 16-25, Radix Ardisiae Crenatae 6-9, Scorpio 3-6, Cortex Albiziae 6-12, Poria 10-15, Lignum Sappan 4-7, Rhizoma Coptidis 2-5, Flos Campsis 5-9, Cera Flava 50-60.
Preferably, a kind of medicine promoting fracture recovery, be made up of the medicine of following weight portion:
Receptaculum Nelumbinis 8, Flos Magnoliae Officinalis 7, Borneolum Syntheticum 0.2, Olibanum 3, Herba Abri 20, Radix Ardisiae Crenatae 8, Scorpio 4, Cortex Albiziae 7, Poria 12, Lignum Sappan 5, Rhizoma Coptidis 3, Flos Campsis 6, Cera Flava 55.
In the preparation, by Receptaculum Nelumbinis, Flos Magnoliae Officinalis, Olibanum, Herba Abri, Radix Ardisiae Crenatae, Scorpio, Cortex Albiziae, Poria, Lignum Sappan, Rhizoma Coptidis, Flos Campsis drug weight 8-10 water slow fire boiling 2-3h doubly, decoction liquor is concentrated to obtain concentrated solution, then adds Borneolum Syntheticum and Cera Flava, make cream drug; Also conventional pharmaceutical methods can be used to make cream drug.
Receptaculum Nelumbinis: [nature and flavor with return through] are bitter, puckery, temperature.Return Liver Channel.[function with cure mainly] removing stasis to stop bleeding.For metrorrhagia, hematuria, bleeding hemorrhoids, postpartum stagnation, lochiorrhea.
Flos Magnoliae Officinalis: [nature and flavor with return through] are bitter, tepor.Return spleen, stomach warp.[function with cure mainly] removing dampness by means of aromatics, regulating the flow of QI to ease the stomach.For taste retention of damp leading to blockage of QI, the vexed distension of breast gastral cavity painful abdominal mass, poor appetite.
Borneolum Syntheticum: [nature and flavor with return through] are pungent, bitter, are slightly cold.GUIXIN, spleen, lung meridian.[function with cure mainly] refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.For calentura coma, convulsions, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, and obstruction of qi in the chest and cardialgia, conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
Olibanum: [nature and flavor with return through] are pungent, bitter, temperature.GUIXIN, liver, spleen channel.[function with cure mainly] analgesic therapy of invigorating blood circulation, detumescence and promoting granulation.For obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation , mass in the abdomen is suffered from abdominal pain, rheumatic arthralgia, the contracture of muscle arteries and veins, traumatic injury, carbuncle skin infection.
Herba Abri: [nature and flavor with return through] sweet, micro-hardship is cool.Return liver, stomach warp.[function with cure mainly] dampness removing jaundice eliminating, heat-clearing and toxic substances removing, dispersing the depressed liver-QI for alleviating pain.For damp and hot yellow cellulitis, side of body rib does not relax, and epigastric distending pain, acute mastitis swells and ache.
Radix Ardisiae Crenatae: [nature and flavor with return through] micro-hardship, pungent, flat.Return lung, Liver Channel.[function with cure mainly] removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, phoenix of dispelling is dehumidified.For laryngopharynx swelling and pain, rheumatic arthralgia, traumatic injury.
Scorpio: [nature and flavor with return through] are pungent, flat; Poisonous.Return Liver Channel.[function with cure mainly] endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation, for liver-wind stirring up internally, spasm is twitched, infantile convulsion, middle air port snail, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
Cortex Albiziae: [nature and flavor with return through] are sweet, flat.GUIXIN, liver, lung meridian.[function with cure mainly] resolving stagnation for tranquilization, promoting blood circulation and detumescence.For irritability, melancholy insomnia, lung abscess, skin ulcer swells, and falls and flutters the pain of injury.
Poria: [nature and flavor with return through] are sweet, light is flat.GUIXIN, lung, spleen, kidney channel.[function with cure mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Lignum Sappan: [nature and flavor with return through] are sweet, salty, flat.GUIXIN, liver, spleen channel.[function with cure mainly] blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.For traumatic injury, the fracture injury of tendon and muscle, the stasis of blood is stagnant to swell and ache, amenorrhea dysmenorrhea, postpartum stagnation, breast ventral spine pain, ulcer sore pain.
Rhizoma Coptidis: [nature and flavor with return through] are bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.[function with cure mainly] heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, palpitation and uneasiness, heat in blood tells mandrill, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.
Flos Campsis: [nature and flavor with return through] are sweet, sour, cold.Return liver, pericardium channel.[function with cure mainly] promoting blood circulation to restore menstrual flow, cooling blood, expelling wind.For menoxenia, amenorrhea and mass in the abdomen, puerperal swelling of the breast, rubella is rubescent, skin pruritus, acne.
Cera Flava: [nature and flavor with return through] are sweet, tepor.Return spleen channel.[function with cure mainly] detoxifies, sore, granulation promoting, pain relieving.Outer for ulcer being unable to heal, ecthyma is rotten to the corn, wound ulceration, burn and scald.
Medicine of the present invention adopts Chinese drug preparation, be there is by compatibility effect of conditioning vim and vigour, kidney tonifying spleen invigorating, promoting blood circulation and detumescence, dredge the meridian passage, pain relieving granulation promoting, enhancing resistance of human body, to promotion bone injury healing, there is good curative effect, and adopt external application for curing, easy to use, safety is high.
Beneficial effect of the present invention: the medicine that promotion fracture provided by the invention is recovered adopts pure Chinese drug preparation, and safety coefficient is high, can accelerate the recovery of fracture patient, prevents patient from occurring sequela.
Detailed description of the invention
Embodiment 1
Promote the medicine recovered of fracturing, be made up of the medicine of following weight portion:
Receptaculum Nelumbinis 8, Flos Magnoliae Officinalis 7, Borneolum Syntheticum 0.2, Olibanum 3, Herba Abri 20, Radix Ardisiae Crenatae 8, Scorpio 4, Cortex Albiziae 7, Poria 12, Lignum Sappan 5, Rhizoma Coptidis 3, Flos Campsis 6, Cera Flava 55.
Embodiment 2
Promote the medicine recovered of fracturing, be made up of the medicine of following weight portion:
Receptaculum Nelumbinis 8, Flos Magnoliae Officinalis 7.5, Borneolum Syntheticum 0.22, Olibanum 5, Herba Abri 21, Radix Ardisiae Crenatae 8, Scorpio 5, Cortex Albiziae 9, Poria 12, Lignum Sappan 5, Rhizoma Coptidis 3, Flos Campsis 7, Cera Flava 55.
Embodiment 3
Promote the medicine recovered of fracturing, be made up of the medicine of following weight portion:
Receptaculum Nelumbinis 9, Flos Magnoliae Officinalis 6, Borneolum Syntheticum 0.25, Olibanum 3.6, Herba Abri 22, Radix Ardisiae Crenatae 8, Scorpio 5, Cortex Albiziae 10, Poria 15, Lignum Sappan 6, Rhizoma Coptidis 4, Flos Campsis 8, Cera Flava 55.
Medicine of the present invention carries out clinical trial to 106 fracture patients between nearly 3 years, fracture patient is divided into two groups, experimental group 66 people, matched group 40 people, the fracture serious symptom degree of two groups of patients is similar, each group of age bracket is similar, experimental group is while fixing, the medicine of the embodiment of the present invention 1 is used to spread on fracture, within 5 days, change dressings 1 time, matched group does not use medicine of the present invention, affected part is fixed simultaneously, result shows, patient's restore cycle of experimental group is average than matched group short 8.5 days, and experimental group patient none there is sequela, matched group has 3 examples to occur that fracture aches, the sequela such as myasthenia.
Model case:
Week certain, man, 28 years old, play ball and cause arm to fracture, pain, swelling, use medicine of the present invention to spread on affected part and be then fixed, change dressings weekly once, pain relief after patient's drug of topical application, the drug of topical application is after 3 days, swelling disappears, and treats 20 days, check affected part callus formation, remove fixing, continue the drug of topical application, 35 days, patient fully recovers, force-applied, without any sequela.
Lee, man, 45 years old, fracture of lower leg, swelling pain, affected part is blue, use medicine of the present invention spread on affected part and be fixed, the drug of topical application 5 days, patient pain almost disappears, the affected part colour of skin recovers normal substantially, 25 days callus formation, within 40 days, patient can walk with descending, and continues medication 5 days, patient can walk freely, without malaise symptoms.

Claims (2)

1. promote the medicine recovered of fracturing, it is characterized in that, be made up of the medicine of following weight portion:
Receptaculum Nelumbinis 5-10, Flos Magnoliae Officinalis 5-9, Borneolum Syntheticum 0.2-0.3, Olibanum 3-5, Herba Abri 16-25, Radix Ardisiae Crenatae 6-9, Scorpio 3-6, Cortex Albiziae 6-12, Poria 10-15, Lignum Sappan 4-7, Rhizoma Coptidis 2-5, Flos Campsis 5-9, Cera Flava 50-60.
2. a kind of medicine that fracture is recovered that promotes according to claim 1, is characterized in that, be made up of the medicine of following weight portion:
Receptaculum Nelumbinis 8, Flos Magnoliae Officinalis 7, Borneolum Syntheticum 0.2, Olibanum 3, Herba Abri 20, Radix Ardisiae Crenatae 8, Scorpio 4, Cortex Albiziae 7, Poria 12, Lignum Sappan 5, Rhizoma Coptidis 3, Flos Campsis 6, Cera Flava 55.
CN201511011167.9A 2015-12-30 2015-12-30 Medicine for promoting bone fracture recovery Pending CN105456402A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108159388A (en) * 2018-03-20 2018-06-15 范学峰 Promote Chinese medicine composition, the preparation method and the usage of union
CN108272930A (en) * 2018-03-20 2018-07-13 范学峰 A kind of Chinese medicine composition, preparation method and use promoting union

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104306620A (en) * 2014-11-12 2015-01-28 马朝栋 Externally applied traditional Chinese medicine for treating fracture and preparation method thereof
CN104984183A (en) * 2015-08-03 2015-10-21 刘艳 Bone fracture nursing medicine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104306620A (en) * 2014-11-12 2015-01-28 马朝栋 Externally applied traditional Chinese medicine for treating fracture and preparation method thereof
CN104984183A (en) * 2015-08-03 2015-10-21 刘艳 Bone fracture nursing medicine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
尚天裕等: "《中国骨伤方药全书》", 31 August 1995, 黑龙江科学技术出版社 *
张冰: "《临床中药学》", 30 September 2012, 中国中医药出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108159388A (en) * 2018-03-20 2018-06-15 范学峰 Promote Chinese medicine composition, the preparation method and the usage of union
CN108272930A (en) * 2018-03-20 2018-07-13 范学峰 A kind of Chinese medicine composition, preparation method and use promoting union

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Application publication date: 20160406