CN105455143A - Composite health walnut oil spray and preparation method thereof - Google Patents
Composite health walnut oil spray and preparation method thereof Download PDFInfo
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- CN105455143A CN105455143A CN201510995627.XA CN201510995627A CN105455143A CN 105455143 A CN105455143 A CN 105455143A CN 201510995627 A CN201510995627 A CN 201510995627A CN 105455143 A CN105455143 A CN 105455143A
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a composite healthy walnut oil spray and a preparation method thereof. The composite health walnut oil spray is functional health food prepared from purely natural medicinal and edible materials such as walnut oil, propolis, mulberry seed oil and semen cassia oil. An oral cavity spray is prepared by adding auxiliary materials by adopting a conventional oral cavity spray preparation method; under the synergistic effect of the auxiliary materials, neurasthenia symptoms such as dysphoria, mental tireness, insomnia and dreaminess, bad appetite, weakness, debilitation and hypomnesis can be treated. The spray is directly absorbed into blood through sublingual mucosal and is convenient to use; decomposition and destroying of the spray by gastric acid are avoided, and metabolism by liver enzyme is eliminated; the medicinal effect is retained, and toxic and side effects of medicaments to gastrointestinal tract and liver are relieved. The product is safe and free of side effects, has an outstanding health effect, can be taken for a long time, and has an extremely good market development prospect.
Description
Technical field
The invention provides a kind of walnut oil compound health-care spray and preparation method, for mind-tranquilizing brain-strengthening, improve body immunity and delay senility, belonging to technical field of health care food.
Background technology
Modern society, rhythm of life is more and more faster, and competitive pressure is increasing, under being in allegro work for a long time, there is neurasthenic various symptom in more people, such as, haves the fidgets, tired mind, the neurasthenia symptoms such as insomnia and dreamful sleep, if things go on like this, even can cause palpitaition, uncomfortable in chest, muscles and bones is ached, limbs fatigue, other symptoms such as pain in low back and legs and sex dysfunction, even may cause hypertension, coronary heart disease, the diseases such as cancer, have a strong impact on the physical and mental health of people.
At present, the medicine being used for the treatment of neurasthenia symptom is mostly Western medicine, and patient in use often brings certain side effect, and curative effect is very micro-, and can't resolve the actual slight illness of patient, result makes status of patient poorer, and quality of life declines; Easily repeatedly, drug dependence is large for general biologic product result for the treatment of, and large to liver damage, Long-Time Service causes body damage, immunity degradation, causes the generation of complication, cannot better for patient palliates the agonizing sufferings; Also there is minority drug effect better fill a prescription and become agent, but take mode drug effect absorption difference, do not reach the object of effectively treatment.
Summary of the invention
The invention provides a kind of walnut oil compound health-care spray, have the fidgets in treatment, tired mind, insomnia and dreamful sleep, be off one's feed, the neurasthenia symptom such as weak weak, failure of memory there is obvious clinical efficacy.
The invention also discloses a kind of preparation method of walnut oil compound health-care spray, technique simply, easily operates, low production cost, is applicable to suitability for industrialized production.
A kind of walnut oil compound health-care spray of the present invention, it is characterized in that being made up by ratio of weight and the number of copies of following medicine:
Walnut oil 25 ~ 45, propolis 10 ~ 25, mulberries seed oil 8 ~ 10, Cassia tora seed oil 8 ~ 10.
The preparation method of a kind of walnut oil compound health-care spray of the present invention, comprises the following steps:
Take above-mentioned raw materials in proportion; Walnut oil, mulberries seed oil, after Cassia tora seed oil mixing preparation becomes ready-mixed oil, then make oil mixture with propolis, then oral spray preparation method routinely adds auxiliary material and makes oral spray, to obtain final product.
[usage and dosage] is oral; 2 times/day; 10 ~ 15ml/ time.
[indication] haves the fidgets, tired mind, insomnia and dreamful sleep, be off one's feed, the neurasthenia symptom such as weak weak, failure of memory.
Health-care effect analysis of the present invention:
Walnut oil: mind-tranquilizing brain-strengthening, containing abundant squalene, Flavonoid substances and polyphenolic substance.Squalene can stimulate circulation, activation physical function cell, anti-inflammation and sterilization, repair cell; Flavonoid substances and polyphenolic substance can strengthen blood vessel dilatation ability, adjusting blood lipid, reduction cholesterol and blood sugar, improve blood vessel microcirculation, and Cell protection by radical damage, does not improve immunity comprehensively, and delaying human body functional organ is old and feeble, maintains health.
Propolis: comprise flavonoids, flavonols and Flavanones etc. containing chromocor compound, account for 4.13% of propolis, have many-sided physiology and pharmacological action, can help human body to prevent and treat various diseases, make the various function normalization of body, enhancingization.Flavone compound in propolis, more than its kind, the height of content exceeded general autonomic drug.All flavone compound is contained to the effective many Chinese herbal medicines for the treatment of coronary heart disease.
Mulberries seed oil: nourishing yin and supplementing blood; Promote the production of body fluid and moisturize.Cure mainly kidney deficiency and liver and the deficiency of blood essence lose have a dizzy spell; Soreness of waist tinnitus; Poliosis; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; The dry constipation of intestines.
Cassia tora seed oil: chemical composition comprises archen (emodin), rheum officinale, Physcion, obtusin, obtusin and glucoside thereof.Effect is removing heat to brighten vision, relaxes bowel, improving water flood.For the puckery pain of hot eyes, the many tear of photophobia, have a headache dizzy, order is secretly failed to understand, constipation.Return liver, kidney, large intestine channel.
The present invention is based on walnut oil, stability and safety, there is mind-tranquilizing brain-strengthening, improve body immunity and deferring senility, add mulberries seed oil, Cassia tora seed oil and propolis work in coordination with compatibility and enhance this effect, and make fatty acid proportion meet nutrition standard, prevent some due to the uneven chronic disease caused of grease absorption, arteriosclerotic generation can be reduced.Above-mentioned each medicine interacts, can mind-tranquilizing brain-strengthening, and improving water flood, improves sleep quality, delay senility; Can significantly improve functions of biological organs, regain one's strength fast and energy, treatment is had the fidgets, tired mind, insomnia and dreamful sleep, be off one's feed, the neurasthenia symptom such as weak weak, failure of memory.Absorb directly into blood by hypoglossis mucous membrane, taking convenience, avoid being destroyed by the decomposition of hydrochloric acid in gastric juice, also can not by the metabolism of liver enzyme, keep drug effect to also mitigate the toxic and side effect of medicine to intestines and stomach and liver simultaneously.
For investigating the clinical efficacy of medicine of the present invention further, choosing 100 routine neurastheniacs and carrying out clinical testing, wherein man 59 example, female 41 example, age 20-48 year, average 32 years old.All patients are because of work, life stress causes greatly having occurred dysphoria, tired mind, insomnia and dreamful sleep, be off one's feed, the neurasthenia symptom such as weak weak, failure of memory, had influence on normal work and life.
Criterion of therapeutical effect:
Cure: clinical symptom disappearance, do not affect normal work and life;
Effective: clinical symptoms are improved, appetite increases, and headache, dizzy, insomnia, the symptom such as weak take a turn for the better, and memory increases;
Invalid: after taking medicine, clinical symptoms are unchanged or increase the weight of.
Result for the treatment of:
Cure: 80 examples; Effective 18 examples; Invalid 2 examples; Total effective rate is 98%.
Good effect of the present invention is: walnut oil, propolis, mulberries seed oil, Cassia tora seed oil are pure natural integration of drinking and medicinal herbs material, utilize their synergy, make mind-tranquilizing brain-strengthening, improving water flood, improve sleep quality, improve the functional health-care food of immunity, there is effect of bushing kidney, beneficial liver, strengthening the spleen and stomach, by regulating viscera gas, blood function, nourishing qi and blood, tranquilizing the mind, plays the health-care efficacy of improving water flood jointly from too many levels.Product safety, to have no side effect, there is remarkable health-care efficacy, can long-term taking, there is the good prospect of marketing.
Detailed description of the invention
To be illustrated further description the present invention by following examples, and do not limit the present invention in any way, under the prerequisite not deviating from technical solution of the present invention, any change that those of ordinary skill in the art made for the present invention easily realize or change all will fall within right of the present invention.
Embodiment 1
Take walnut oil 25g, after mulberries seed oil 8g, Cassia tora seed oil 8g mixing preparation become ready-mixed oil, then make oil mixture with propolis 10g, then oral spray preparation method routinely adds auxiliary material and makes oral spray, to obtain final product.
Embodiment 2
Take walnut oil 35g, after mulberries seed oil 9g, Cassia tora seed oil 9g mixing preparation become ready-mixed oil, then make oil mixture with 15g propolis, then oral spray preparation method routinely adds auxiliary material and makes oral spray, to obtain final product.
Embodiment 3
Take walnut oil 45g, after mulberries seed oil 10g, Cassia tora seed oil 10g mixing preparation become ready-mixed oil, then restrain into oil mixture with propolis 25, then oral spray preparation method routinely adds auxiliary material and makes oral spray, to obtain final product.
Selected following case further illustrates curative effect of the present invention:
Case 1
Certain man, 28 years old, paperwork person, go to a doctor with " sleep-disorder ": dysphoria and insomnia, parched lips was flushing, thirst and desire for cold drink, and four limbs are twitched slightly, and urine Huang is few, and tongue is red, tongue is few, deep,thready and rapid pulse.Treated by product of the present invention, oral; 2 times/day; 10 ~ 15ml/ time 15 days was 1 course for the treatment of, totally 2 courses for the treatment of, recovery from illness.Follow up a case by regular visits to 12 months, the state of an illness does not recur.
Case 2
Certain man, 37 years old, bank clerk, clinical symptoms: night does not fall asleep, palpitation with irritability, dry throat, feverishness in palms and soles, red, the few tongue of tongue, arteries and veins was thin and count.Treated by product of the present invention, oral; 2 times/day; 10 ~ 15ml/ time 15 days was 1 course for the treatment of, totally 3 courses for the treatment of, and illness disappears.Follow up a case by regular visits to 12 months, the state of an illness does not recur.
Case 3
Certain female, 46 years old, line manager, main suit previously suffered from neurosis 8 years, imitates less, before first quarter moon, lie awake all night, have difficulty in going to sleep, dizziness and tinnitus, hectic fever night sweat all over the agent taking calmness of calming the nerves, dysphoria in chestpalms-soles, soreness and weakness of waist and knees, and red, the few tongue of tongue, deeptensepulse is counted accurately.Treated by product of the present invention, oral; 2 times/day; 10 ~ 15ml/ time, within 15 days, be 1 course for the treatment of, totally 5 courses for the treatment of, body recovery is normal.Follow up a case by regular visits to 12 months, the state of an illness does not recur.
Case 4
Certain female, 34 years old, secretarial, medical syndrome: vexedly to sleep less, dry throat, feverishness in palms and soles, body was become thin, and has a dizzy spell, red, the few tongue of tongue, thready rapid pulse.Treated by product of the present invention, oral; 2 times/day; 10 ~ 15ml/ time, 15 days was 1 course for the treatment of, and illness is all recovered.Follow up a case by regular visits to 12 months, the state of an illness does not recur.
Experimental example 1
The present invention sleep soundly on animal used as test the impact of time
1.1 material
Given the test agent: medicine prepared by embodiment 1 ~ embodiment 3.
Positive control drug: Three Jins, diazepam tablet Taiyuan restriction factory, lot number 030603, every sheet 2.5mg, to be configured to 15mg% suspension with 0.5 shuttle methylated cellulose aqueous solution, to face the used time and now join.
Walnut oil control group, Cassia tora seed oil control group: Beijing Ao Neisitai Bioisystech Co., Ltd produces.
Carbrital Serva import, chemical plant packing is known in upper sea-run.Be configured to the solution of desired concn before use.
Animal used as test: Kunming mouse, laboratory animal room of Shanxi Institute of Traditional Chinese Medicine provides, male and female half and half, body weight 20g soil 2g.
1.2 methods and result
1.2.1 medicine closes the impact of lower HD on mouse yellow Jackets
Mouse is divided into control group, embodiment 1 ~ embodiment 3, walnut oil control group, Cassia tora seed oil control group and stable positive controls etc. seven groups at random, gastric infusion, and dosage is the same, control group gavage equivalent distilled water, every day 1 time, continuous 7 days.After last administration 30 minutes, lumbar injection yellow Jackets 30mg/Kg, in latter 15 minutes of record injection, mouse righting reflex loss reached the mouse number of more than Imin, as explaining down glirid number.Result shows: embodiment 1 ~ embodiment 3 treatment group mouse sleep number of elements is significantly more than control group, and particularly embodiment 1 ~ embodiment 3 treatment group is apparently higher than walnut oil control group, Cassia tora seed oil control group, shows that the present invention has coordinative role.Specific experiment the results are shown in Table 1:
Table 1 medicine closes the impact of lower sleep to mouse yellow Jackets
Note: compare with control group through t inspection: * P<0.05, * * P<0.01:
1.2.2 medicine is on the impact of mouse yellow Jackets HD
The mouse of getting above-mentioned experiment respectively organizes 15, after autonomic activities test, next day is administered once, after administration 30 minutes, lumbar injection yellow Jackets 50mg/Kg, record mouse righting reflex loss time of occurrence is as time for falling asleep, and the righting reflex loss duration is as the length of one's sleep.Result shows: embodiment 1 ~ embodiment 3 treatment group significant prolongation yellow Jackets HD mouse sleep time.Yellow Jackets HD mouse time for falling asleep is had no significant effect, in table 2
Note: t checks, and control group compares: * * * P<0.001
Conclusion: what given the test agent embodiment 1 ~ embodiment 3 treatment group and walnut oil control group, Cassia tora seed oil control group can increase that yellow Jackets explain lower HD enters glirid number, extend yellow Jackets dosage mouse sleep time, show that the present invention has sedative-hypnotic property, and apparently higher than walnut oil control group, Cassia tora seed oil control group, the present invention has coordinative role.
Claims (3)
1. a walnut oil compound health-care spray, it is characterized in that being made up by ratio of weight and the number of copies of following medicine:
Walnut oil 25 ~ 45, propolis 10 ~ 25, mulberries seed oil 8 ~ 10, Cassia tora seed oil 8 ~ 10.
2. the preparation method of a kind of walnut oil compound health-care spray according to claim 1, comprises the following steps:
Take above-mentioned raw materials in proportion; Walnut oil, mulberries seed oil, after Cassia tora seed oil mixing preparation becomes ready-mixed oil, then make oil mixture with propolis, then oral spray preparation method routinely adds auxiliary material and makes oral spray, to obtain final product.
3. walnut oil compound health-care spray according to claim 1 is had the fidgets in treatment, tired mind, insomnia and dreamful sleep, be off one's feed, the medical application of the neurasthenia symptom such as weak weak, failure of memory.
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Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1297754A (en) * | 1999-11-26 | 2001-06-06 | 云南金碧制药厂 | Tonic food capable of lowering blood lipoid, resisting senility and regulating immunity |
| CN1348783A (en) * | 2000-10-16 | 2002-05-15 | 常纪庆 | Shanbao Oil (contg. plant seed oil and insect power) capsule |
| CN102366426A (en) * | 2011-10-26 | 2012-03-07 | 江苏江大源生态生物科技有限公司 | Propolis tincture for external use and preparation method thereof |
| CN102919842A (en) * | 2012-11-14 | 2013-02-13 | 汾州裕源土特产品有限公司 | Walnut oil soft capsule with antioxidation function and preparation method of same |
| CN104194653A (en) * | 2014-08-27 | 2014-12-10 | 袁航 | Manufacturing method of care ointment for wood handhold parts |
| CN104365879A (en) * | 2014-11-08 | 2015-02-25 | 全椒县尹氏油脂有限公司 | Walnut oil with functions of beautifying face and protecting health |
| CN104705652A (en) * | 2015-03-30 | 2015-06-17 | 哈尔滨工业大学 | Soft capsule with anti-oxidation function and preparation method of soft capsule |
| CN104738219A (en) * | 2015-04-01 | 2015-07-01 | 万雄集团股份有限公司 | Herbal medicine health blend oil |
-
2015
- 2015-12-28 CN CN201510995627.XA patent/CN105455143A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1297754A (en) * | 1999-11-26 | 2001-06-06 | 云南金碧制药厂 | Tonic food capable of lowering blood lipoid, resisting senility and regulating immunity |
| CN1348783A (en) * | 2000-10-16 | 2002-05-15 | 常纪庆 | Shanbao Oil (contg. plant seed oil and insect power) capsule |
| CN102366426A (en) * | 2011-10-26 | 2012-03-07 | 江苏江大源生态生物科技有限公司 | Propolis tincture for external use and preparation method thereof |
| CN102919842A (en) * | 2012-11-14 | 2013-02-13 | 汾州裕源土特产品有限公司 | Walnut oil soft capsule with antioxidation function and preparation method of same |
| CN104194653A (en) * | 2014-08-27 | 2014-12-10 | 袁航 | Manufacturing method of care ointment for wood handhold parts |
| CN104365879A (en) * | 2014-11-08 | 2015-02-25 | 全椒县尹氏油脂有限公司 | Walnut oil with functions of beautifying face and protecting health |
| CN104705652A (en) * | 2015-03-30 | 2015-06-17 | 哈尔滨工业大学 | Soft capsule with anti-oxidation function and preparation method of soft capsule |
| CN104738219A (en) * | 2015-04-01 | 2015-07-01 | 万雄集团股份有限公司 | Herbal medicine health blend oil |
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Application publication date: 20160406 |