CN105434645A - Traditional Chinese medicine composition used for treating facial nerve paralysis - Google Patents

Traditional Chinese medicine composition used for treating facial nerve paralysis Download PDF

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Publication number
CN105434645A
CN105434645A CN201511003417.4A CN201511003417A CN105434645A CN 105434645 A CN105434645 A CN 105434645A CN 201511003417 A CN201511003417 A CN 201511003417A CN 105434645 A CN105434645 A CN 105434645A
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China
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parts
chinese medicine
traditional chinese
medicine composition
facial nerve
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CN201511003417.4A
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王璐
许璟
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Qingdao Changanda Pharmaceutical Co Ltd
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Qingdao Changanda Pharmaceutical Co Ltd
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Priority to CN201511003417.4A priority Critical patent/CN105434645A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine composition used for treating facial nerve paralysis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 25-39 parts of lotus plumule, 21-36 parts of long pepper, 16-30 parts of common coltsfoot flower, 12-28 parts of common St.John's wort herb, 11-18 parts of radix astragali preparata, 9-13 parts of herb of Indian adenosma, 8-16 parts of pale butterflybush flower and 3-9 parts of nux vomica. The traditional Chinese medicine composition has the beneficial effects that compatibility of the selected medicinal materials is reasonable and conforms to the theories of traditional Chinese medicine and modern medicine; the traditional Chinese medicine composition has the functions of promoting blood circulation and regulating collaterals, removing wind and dampness, supplementing qi and promoting the production of body fluid and clearing heat for detumescence, is convenient to use, has good absorption effects and does not have adverse, toxic or side effects; through clinical verification, the traditional Chinese medicine composition has wonderful prevention and treatment effects on facial nerve paralysis and is suitable for prevention and treatment of facial nerve paralysis.

Description

Be used for the treatment of prosopoplegic Chinese medicine composition
Technical field
The present invention relates to one and be used for the treatment of prosopoplegic Chinese medicine composition.
Background technology
Facial paralysis and facial paralysis, the wapperijaw that is otherwise known as bar, wapperijaw etc. are a kind of maxillofacial diseases of more complicated, and be a kind of commonly encountered diseases that is principal character with facial expression muscle group dyskinesia, general symptom is facial hemiparalysis.It is a kind of commonly encountered diseases, frequently-occurring disease, not by age limit.Patient facial region is often the most basic to lift the actions such as eyebrow, eye closing, drum mouth and all cannot complete.Facial paralysis patient often in early morning wash one's face, gargle time catch sight of that side buccal action is ineffective, face is crooked.The complete paralytic of sick side surface part histrionic muscles, forehead line disappears, palpebral fissure expands, nasolabial fold is smooth, ptosis of labial angle, and time grinningly, bicker is askew to strong lateral deviation.The actions such as sick side can not make wrinkle volume, frown, close order, air-blowing and be in a pout.The drum cheek, with when whistling, leaks gas because Ipsilateral lip can not close.During feed, food debris is often stranded in the tooth buccal space of disease side, and often has saliva to drop down from this side.Because lacrimal point is with lower eyelid entropion, make tear can not be excessive by normal drainage.Facial paralysis is divided into peripheral and central two kinds.Wherein peripheral facial paralysis sickness rate is very high, and the most common person is facial neuritis or Bell's palsy.The cervical bone that has its source in of the facial paralysis crooked pressuring nerve that misplaces causes neural spasm and forms facial neural convulsion paralysis, cause the complete paralytic of facial muscle, forehead line disappears, palpebral fissure expands, nasolabial fold is smooth, ptosis of labial angle, and time grinningly, bicker waits disease to strong lateral deviation is askew.According to the difference at nerve damage position, facial paralysis should be divided into infranuclear facial palsy and central facial palsy, and the concrete clinical manifestation of the two is also different.Infranuclear facial palsy refers to the facial paralysis caused by Facial nerve motor fiber generation pathological changes.Pathological changes can be positioned at the position of below nucleus of facial nerve, as pon bottom, facial canal, middle ear or the parotid gland etc.Its pathological changes side pantomimia myoparalysis.Show as that eyelid can not close, can not frown, drum cheek gas leakage etc., can have the feature such as 2/3 hypogeusia and salivation obstacle before audition change, tongue, wherein the most common person is facial neuritis (i.e. Bell's palsy).Central facial palsy refers to disease damage between cortical centre more than nucleus of facial nerve, the facial paralysis namely caused when side corticobulbar tract are impaired.Cell due to nucleus of facial nerve top accepts the fiber of both sides corticobulbar tract, its aixs cylinder composition Facial nerve motor fiber, histrionic muscles more than domination homonymy palpebral fissure, and the cell of nucleus of facial nerve bottom only accepts the fiber of contralateral cortex brain stem bundle, the motor fiber of its aixs cylinder composition nervus facialis, histrionic muscles below domination homonymy palpebral fissure, therefore the muscle of facial expression paralysis of below contralateral palpebral fissure is shown as during central facial palsy, normal with the quadriplegia with facial paralysis homonymy, the clinical characters such as Ageustia and salivation obstacle.The prosopoplegic medicine of current treatment has a lot, and at present effective Therapeutic Method has acupuncture, oral and injection Western medicine etc.And acupuncture effect is slow, need to treat for a long time, Western medicine has side effect mostly, takes for a long time and can cause patient's gastrointestinal upset.Therefore be used for the treatment of prosopoplegic medicine must safety, effectively, have no side effect, and Chinese materia medica is as the traditional medicine of China, there is the advantages such as effect is strong, instant effect, lasting medicine, and there is no dependency, drug resistance and toxic and side effects, therefore select a kind of Chinese medicine composition to be used for the treatment of facial paralysis, for treatment facial paralysis, there is very important clinical meaning.
Summary of the invention
Technical problem to be solved by this invention is: provide one and be used for the treatment of prosopoplegic Chinese medicine composition, selected by Chinese medicine composition of the present invention, medical material compatibility is suitable, meet Chinese medicine and modern medicine theory, there is effect of invigorate blood circulation easypro network, expelling wind and dampness, supplementing QI for promoting the production of body fluid, clearing heat for detumescence, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, there are fabulous prevention and therapeutic effect to facial paralysis, are suitable for prosopoplegic prevention and treatment.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
One provided by the invention is used for the treatment of prosopoplegic Chinese medicine composition, be made up of the raw material of Chinese medicine of following weight portion: Plumula Nelumbinis 25-39 part, BIBO 21-36 part, Flos Farfarae 16-30 part, Herba Hyperici Monogyni 12-28 part, Radix Astragali Preparata 11-18 part, Herba Adenosmae 9-13 part, Flos Buddlejae 8-16 part, Semen Strychni 3-9 part.
Preferably, Chinese medicine provided by the invention is made up of the raw material of Chinese medicine of following weight portion: Plumula Nelumbinis 33 parts, BIBO 29 parts, Flos Farfarae 25 parts, Herba Hyperici Monogyni 20 parts, Radix Astragali Preparata 14 parts, Herba Adenosmae 11 parts, Flos Buddlejae 10 parts, Semen Strychni 6 parts.
Usage and consumption: adopt conventional Chinese medicine decocting method to decoct water, take, every day 1 dose, point take for 2 times, within 15 days, is a course for the treatment of, generally take 2-3 the course for the treatment of successful.
Clinical data: 1, case selection: select the routine clinical observation of facial paralysis patient 100 of making a definite diagnosis.2, medicament selection:
Patient takes this Chinese medicine composition, adopts conventional Chinese medicine decocting method to decoct water, takes, every day 1 dose, and dividing and take for 2 times, 15 days is a course for the treatment of.3, efficacy determination: (1) cures: widening of palpebral fissure, hypophasis, and nasolabial fold shoals, and bicker is askew to transference cures such as strong sides; Face nerve rejuvenates, and health is fully recovered, and gets well.(2) effective: above-mentioned symptom is alleviated to some extent, and face nerve rejuvenates, health is fully recovered, and gets well.(3) invalid: disease is unchanged.4, result:
Cure 90 examples, effective 8 examples, invalid 2 examples, total effective rate 98%.Beneficial effect of the present invention:
Selected by Chinese medicine composition of the present invention, medical material compatibility is suitable, meet Chinese medicine and modern medicine theory, there is effect of invigorate blood circulation easypro network, expelling wind and dampness, supplementing QI for promoting the production of body fluid, clearing heat for detumescence, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, there are fabulous prevention and therapeutic effect to facial paralysis, are suitable for prosopoplegic prevention and treatment.
Detailed description of the invention
Embodiment 1
The one that the present embodiment provides is used for the treatment of prosopoplegic Chinese medicine composition, is made up of the raw material of Chinese medicine of following weight portion: Plumula Nelumbinis 33 parts, BIBO 29 parts, Flos Farfarae 25 parts, Herba Hyperici Monogyni 20 parts, Radix Astragali Preparata 14 parts, Herba Adenosmae 11 parts, Flos Buddlejae 10 parts, Semen Strychni 6 parts.
Model case:
1, Wei, female, 49 years old.There is facial hemiparalysis because having a cold in patient, used multiple method to treat, and take a turn for the better to some extent, but facial hemiparalysis was still bad.After taking 2 courses for the treatment of of Chinese medicine composition of the present invention, symptom is obviously alleviated, and continues to take 3 courses for the treatment of, and clinical symptoms all disappears.Follow up a case by regular visits to and do not recur so far.2, week certain, man, 46 years old.Patient is diagnosed as facial paralysis.After taking 2 courses for the treatment of of Chinese medicine composition of the present invention, health is rehabilitation gradually, and symptom is obviously alleviated, and continues to take 3 courses for the treatment of, above transference cure.Follow up a case by regular visits to and do not recur so far.3, high certain, man, 60 years old.Patient is diagnosed as facial paralysis.After people recommends to take 2 courses for the treatment of of Chinese medicine composition of the present invention, symptom is clearly better, after continuing to take 3 courses for the treatment of, above transference cure, facial perception and muscular movement functional rehabilitation normal, physical recovery is healthy, not recurrence.

Claims (2)

1. one kind is used for the treatment of prosopoplegic Chinese medicine composition, it is characterized in that, be made up of the raw material of Chinese medicine of following weight portion: Plumula Nelumbinis 25-39 part, BIBO 21-36 part, Flos Farfarae 16-30 part, Herba Hyperici Monogyni 12-28 part, Radix Astragali Preparata 11-18 part, Herba Adenosmae 9-13 part, Flos Buddlejae 8-16 part, Semen Strychni 3-9 part.
2. Chinese medicine according to claim 1, is characterized in that, is made up of the raw material of Chinese medicine of following weight portion: Plumula Nelumbinis 33 parts, BIBO 29 parts, Flos Farfarae 25 parts, Herba Hyperici Monogyni 20 parts, Radix Astragali Preparata 14 parts, Herba Adenosmae 11 parts, Flos Buddlejae 10 parts, Semen Strychni 6 parts.
CN201511003417.4A 2015-12-29 2015-12-29 Traditional Chinese medicine composition used for treating facial nerve paralysis Pending CN105434645A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103816476A (en) * 2013-12-02 2014-05-28 蒋跃 Medicine composition for treating injury and paralysis of oculomotor nerve and preparation method and application thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103816476A (en) * 2013-12-02 2014-05-28 蒋跃 Medicine composition for treating injury and paralysis of oculomotor nerve and preparation method and application thereof

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Application publication date: 20160330