CN105412782A - Traditional Chinese medicine composition for treating infantile constipation and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating infantile constipation and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicine and particularly relates to a traditional Chinese medicine composition for treating infantile constipation. According to the technical scheme, the traditional Chinese medicine composition is prepared from, by weight, 12-18 g of raw rhizoma atractylodis macrocephalae, 3-8 g of fructus aurantii, 3-8 g of caulis perllae, 15-25 g of radix scrophulariae, 5-15 g of rhizomes of rehmannia, 2-6 g of blackberrykiky rhizomes, 2-6 g of amomum villosum, 2-6 g of rhizoma pinelliae preparata, 3-8 g of magnolia officinalis, 10-15 g of dried tangerine or orange peel and 6-12 g of poria cocos. According to the technical scheme, by regulating the spleen and the stomach of infants and regulating qi and nourishing yin, appetite is increased, and therefore infantile constipation can be treated.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of infantile constipation and preparation method thereof.
Background technology
Infantile constipation is a kind of common multiple disease, and how repeatedly to fall ill.Generally speaking constipation refers to and is hard and dry, hard, constipated obstructed, and defecation time interval (being greater than 2 days) comparatively of a specified duration is though or have awareness of defecation and can not arrange stool.
Current medical science is generally promote that gastrointestinal peristalsis and catharsis are master for the treatment of infantile constipation.Conventional catharsis agent local irritation cathartic glycerol/sodium chloride (glycerin), irritant purgative Radix Et Rhizoma Rhei, Folium Sennae, demulcent cathartics, solvent-borne type catharsis agent lactulose etc.; Conventional digestive tract power reinforcing medicine has mosapride.But above-mentioned method can only be taken stopgap measures and can not be effected a permanent cure, and is merely able to respite constipation, but can not tackle the problem at its root.Also having some Chinese medicine compositions, is basic principle substantially with loosening bowel to relieve constipation, and dosage, for bigger than normal children's and take medicine can relief of symptoms, can increase the weight of the degree of constipation on the contrary after drug withdrawal.
Summary of the invention
The object of the present invention is to provide one effectively can treat infantile constipation,
Treat a Chinese medicine composition for infantile constipation, be prepared from by the raw material of following weight:
Rhizoma Atractylodis Macrocephalae 12-18g, Fructus Aurantii 3-8g, Caulis Perillae 3-8g, Radix Scrophulariae 15-25g, Radix Rehmanniae 5-15g, Rhizoma Belamcandae 2-6g, Fructus Amomi 2-6g, Rhizoma Pinelliae 2-6g, Cortex Magnoliae Officinalis 3-8g, Pericarpium Citri Reticulatae 10-15g, Poria 6-12g.
The Chinese medicine composition for the treatment of infantile constipation, is prepared from by the raw material of following weight: Rhizoma Atractylodis Macrocephalae 14-16g, Fructus Aurantii 5-7g, Caulis Perillae 5-7g, Radix Scrophulariae 18-23g, Radix Rehmanniae 7-13g, Rhizoma Belamcandae 3-5g, Fructus Amomi 3-5g, Rhizoma Pinelliae 3-5g, Cortex Magnoliae Officinalis 5-7g, Pericarpium Citri Reticulatae 11-14g, Poria 8-10g.
The Chinese medicine composition for the treatment of infantile constipation, is prepared from by the raw material of following weight: Rhizoma Atractylodis Macrocephalae 15g, Fructus Aurantii 6g, Caulis Perillae 6g, Radix Scrophulariae 20g, Radix Rehmanniae 10g, Rhizoma Belamcandae 4g, Fructus Amomi 5g, Rhizoma Pinelliae 4g, Cortex Magnoliae Officinalis 6g, Pericarpium Citri Reticulatae 12g, Poria 9g.
The preparation method of the Chinese medicine composition for the treatment of infantile constipation is: it is characterized in that: concrete steps are:
(1) raw material is got ready by above-mentioned weight;
(2) by 3, Rhizoma Zingiberis Recens, 4, Fructus Jujubae and Fructus Jujubae are torn, and as extra conductant ingredient in this, put into medicinal cupping;
(3) Fructus Amomi is smashed to pieces, sieve for subsequent use;
(4) by Fructus Aurantii, Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Rhizoma Belamcandae, Poria vapor distillation extracts volatile oil, and the another device of the aqueous solution after distillation is collected;
(5) by Rhizoma Atractylodis Macrocephalae, Caulis Perillae, Radix Scrophulariae, the Radix Rehmanniae, Rhizoma Pinelliae, Cortex Magnoliae Officinalis, cold water soaks half an hour, decocts with water twice with the medicinal residues after above-mentioned distillating extracting oil; First time adds injection volume 5.5 times of soak by water 2.5 hours, and second time adds injection volume 4.5 times of soak by water 1.5 hours, collecting decoction, then adds the aqueous solution after above-mentioned distillation, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.15-1.18, lets cool, and adds ethanol and reaches 70% to alcohol content, stir evenly, and leaves standstill cold preservation (3-6 DEG C) 24 hours, filters; Filtrate recycling ethanol, and the water dilution being concentrated into that relative density (1.16-1.17) (60 DEG C) adds equivalent, stir evenly, then leave standstill cold preservation (3-6 DEG C) 24 hours, filter;
(6) filtrate adds above-mentioned Fructus Amomi fine powder, stirs thereupon, and regulates pH4.5-6.0, add water and be adjusted to 800ml, and filter, sterilizing, to obtain final product.
The Chinese medicine composition for the treatment of infantile constipation, described Chinese medicine composition can be pill, capsule, granule, powder or oral liquid.
The application of Chinese medicine composition in treatment infantile constipation.
beneficial effect of the present invention: the Chinese medicine that the invention provides a kind for the treatment of infantile constipation completely newly, overcomes in Chinese medicine formula and passes through to add cathartic: such as Radix Et Rhizoma Rhei, Folium Sennae etc. improve the symptom of constipation.By the taste of conditioning children's in the present invention, coordinate YIN nourishing of regulating the flow of vital energy, increase appetite, thus infantile constipation is fundamentally treated.Rhizoma Atractylodis Macrocephalae, Caulis Perillae, Fructus Amomi, Poria is controlled at taste, helps it to be elevated; Radix Scrophulariae heat clearing away; Removing heat from blood, nourishing YIN to lower pathogenic fire; The Radix Rehmanniae is controlled at clearing away heat and cooling blood, and tonifying YIN promotes the production of body fluid; Fructus Aurantii regulating the flow of QI to ease the stomach, the stagnant relieving distension of row; Rhizoma Belamcandae heat-clearing and toxic substances removing; Rhizoma Pinelliae, drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Cortex Magnoliae Officinalis circulation of qi promoting removing food stagnancy; Dampness is except full; Pericarpium Citri Reticulatae dampness and can spleen benefiting and stimulating the appetite.Above-mentioned drug matching, plays synergism each other, and strengthen spleen and stomach function, YIN nourishing of regulating the flow of vital energy, heat-clearing and toxic substances removing, thus the problem fundamentally can treating infantile constipation, achieve significant curative effect.
typical clinical case:
Korea Spro * *, 9 years old, from cradle to Childhood, is all once defecate for seven or eight days at every turn, causes eating in the four or five day seldom, and attention is not also concentrated; Be the head of a family's glycerin when major part, utilize the high concentration of glycerol, namely highly ooze effect, allow more moisture infiltrate intestinal wall, softening stool, stimulate intestinal wall, reflexive defecation that causes reacts, and is adding its lubrication, and stool can be made to discharge; Consider that long-term glycerin neither way, seeking medical advice and medicine everywhere, take a lot of traditional Chinese medical science prescriptions, is all can make stool at three to four days once at period in a medicine, takes medicine after terminating, still maintains seven to eight days and once defecate, cannot deal with problems at all.Take this medicine after the course for the treatment of, constipation condition improved, defecates general three to four days once; Take this medicine after two courses for the treatment of, effect is more obvious, stool the chances are one to two day once.
clinical trial
According to " GCP " and " new Chinese medicine guideline of clinical investigations ", the clinical research of infantile constipation is carried out to Chinese medicine of the present invention.Data and method: the health tea being used for the treatment of infantile constipation of the present invention, treatment infantile constipation patient 200 example, through 1 course of therapy, recovery from illness 73 example, effective 102 examples; Through two course of therapy recovery from illness 144 examples, account for 72%; Effective 38 examples, account for 19%; Effective 12 examples, account for 6%; Invalid six example, account for 3%, 2 the course for the treatment of total effective rate be 91%.
specific implementation method
further illustrate technical scheme of the present invention below by specific embodiment, but technical scheme of the present invention is not limited with following embodiment.
embodiment 1
Treat a Chinese medicine composition for infantile constipation, be prepared from by the raw material of following weight:
Rhizoma Atractylodis Macrocephalae 12g, Fructus Aurantii 3g, Caulis Perillae 3g, Radix Scrophulariae 15g, Radix Rehmanniae 5g, Rhizoma Belamcandae 2g, Fructus Amomi 2g, Rhizoma Pinelliae 2g, Cortex Magnoliae Officinalis 3g, Pericarpium Citri Reticulatae 10g, Poria 6g.
The preparation method of the Chinese medicine composition for the treatment of infantile constipation is: it is characterized in that: concrete steps are:
(1) raw material is got ready by above-mentioned weight;
(2) by 3, Rhizoma Zingiberis Recens, 4, Fructus Jujubae and Fructus Jujubae are torn, and as extra conductant ingredient in this, put into medicinal cupping;
(3) Fructus Amomi is smashed to pieces, sieve for subsequent use;
(4) by Fructus Aurantii, Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Rhizoma Belamcandae, Poria vapor distillation extracts volatile oil, and the another device of the aqueous solution after distillation is collected;
(5) by Rhizoma Atractylodis Macrocephalae, Caulis Perillae, Radix Scrophulariae, the Radix Rehmanniae, Rhizoma Pinelliae, Cortex Magnoliae Officinalis, cold water soaks half an hour, decocts with water twice with the medicinal residues after above-mentioned distillating extracting oil; First time adds injection volume 5.5 times of soak by water 2.5 hours, and second time adds injection volume 4.5 times of soak by water 1.5 hours, collecting decoction, then adds the aqueous solution after above-mentioned distillation, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.15-1.18, lets cool, and adds ethanol and reaches 70% to alcohol content, stir evenly, and leaves standstill cold preservation (3-6 DEG C) 24 hours, filters; Filtrate recycling ethanol, and the water dilution being concentrated into that relative density (1.16-1.17) (60 DEG C) adds equivalent, stir evenly, then leave standstill cold preservation (3-6 DEG C) 24 hours, filter;
(6) filtrate adds above-mentioned Fructus Amomi fine powder, stirs thereupon, and regulates pH4.5-6.0, add water and be adjusted to 800ml, and filter, sterilizing, to obtain final product.
Embodiment 2
Treat a Chinese medicine composition for infantile constipation, be prepared from by the raw material of following weight: Rhizoma Atractylodis Macrocephalae 18g, Fructus Aurantii 8g, Caulis Perillae 8g, Radix Scrophulariae 25g, Radix Rehmanniae 15g, Rhizoma Belamcandae 6g, Fructus Amomi 6g, Rhizoma Pinelliae 6g, Cortex Magnoliae Officinalis 8g, Pericarpium Citri Reticulatae 15g, Poria 12g.
Its preparation method is with embodiment 1.
Embodiment 3
Treat a Chinese medicine composition for infantile constipation, be prepared from by the raw material of following weight: Rhizoma Atractylodis Macrocephalae 14g, Fructus Aurantii 5g, Caulis Perillae 5g, Radix Scrophulariae 18g, Radix Rehmanniae 7g, Rhizoma Belamcandae 3g, Fructus Amomi 3g, Rhizoma Pinelliae 3g, Cortex Magnoliae Officinalis 5g, Pericarpium Citri Reticulatae 11g, Poria 8g.
Its preparation method is with embodiment 1.
Embodiment 4
Treat a Chinese medicine composition for infantile constipation, be prepared from by the raw material of following weight: Rhizoma Atractylodis Macrocephalae 16g, Fructus Aurantii 7g, Caulis Perillae 7g, Radix Scrophulariae 23g, Radix Rehmanniae 13g, Rhizoma Belamcandae 5g, Fructus Amomi 5g, Rhizoma Pinelliae 5g, Cortex Magnoliae Officinalis 7g, Pericarpium Citri Reticulatae 14g, Poria 10g.
Its preparation method is with embodiment 1.
Embodiment 5:
Treat a Chinese medicine composition for infantile constipation, be prepared from by the raw material of following weight: Rhizoma Atractylodis Macrocephalae 15g, Fructus Aurantii 6g, Caulis Perillae 6g, Radix Scrophulariae 20g, Radix Rehmanniae 10g, Rhizoma Belamcandae 4g, Fructus Amomi 5g, Rhizoma Pinelliae 4g, Cortex Magnoliae Officinalis 6g, Pericarpium Citri Reticulatae 12g, Poria 9g.
Its preparation method is with embodiment 1.
Claims (6)
1. treat the Chinese medicine composition of infantile constipation for one kind, it is characterized in that: be prepared from by the raw material of following weight: Rhizoma Atractylodis Macrocephalae 12-18g, Fructus Aurantii 3-8g, Caulis Perillae 3-8g, Radix Scrophulariae 15-25g, Radix Rehmanniae 5-15g, Rhizoma Belamcandae 2-6g, Fructus Amomi 2-6g, Rhizoma Pinelliae 2-6g, Cortex Magnoliae Officinalis 3-8g, Pericarpium Citri Reticulatae 10-15g, Poria 6-12g.
2. the Chinese medicine composition for the treatment of infantile constipation as claimed in claim 1, it is characterized in that: be prepared from by the raw material of following weight: Rhizoma Atractylodis Macrocephalae 14-16g, Fructus Aurantii 5-7g, Caulis Perillae 5-7g, Radix Scrophulariae 18-23g, Radix Rehmanniae 7-13g, Rhizoma Belamcandae 3-5g, Fructus Amomi 3-5g, Rhizoma Pinelliae 3-5g, Cortex Magnoliae Officinalis 5-7g, Pericarpium Citri Reticulatae 11-14g, Poria 8-10g.
3. the Chinese medicine composition for the treatment of infantile constipation as claimed in claim 2, is characterized in that: be prepared from by the raw material of following weight: Rhizoma Atractylodis Macrocephalae 15g, Fructus Aurantii 6g, Caulis Perillae 6g, Radix Scrophulariae 20g, Radix Rehmanniae 10g, Rhizoma Belamcandae 4g, Fructus Amomi 5g, Rhizoma Pinelliae 4g, Cortex Magnoliae Officinalis 6g, Pericarpium Citri Reticulatae 12g, Poria 9g.
4. the preparation method of the Chinese medicine composition of the treatment infantile constipation as described in claim as arbitrary in claim 1-3 is: it is characterized in that: concrete steps are:
(1) raw material is got ready by above-mentioned weight;
(2) by 3, Rhizoma Zingiberis Recens, 4, Fructus Jujubae and Fructus Jujubae are torn, and as extra conductant ingredient in this, put into decocting container;
(3) Fructus Amomi is smashed to pieces, sieve for subsequent use;
(4) by Fructus Aurantii, Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Rhizoma Belamcandae, Poria vapor distillation extracts volatile oil, and the another device of the aqueous solution after distillation is collected;
(5) by Rhizoma Atractylodis Macrocephalae, Caulis Perillae, Radix Scrophulariae, the Radix Rehmanniae, Rhizoma Pinelliae, Cortex Magnoliae Officinalis, cold water soaks half an hour, decocts with water twice with the medicinal residues after above-mentioned distillating extracting oil; First time adds injection volume 5.5 times of soak by water 2.5 hours, and second time adds injection volume 4.5 times of soak by water 1.5 hours, collecting decoction, then adds the aqueous solution after above-mentioned distillation, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.15-1.18, lets cool, and adds ethanol and reaches 70% to alcohol content, stir evenly, and leaves standstill cold preservation (3-6 DEG C) 24 hours, filters; Filtrate recycling ethanol, and the water dilution being concentrated into that relative density (1.16-1.17) (60 DEG C) adds equivalent, stir evenly, then leave standstill cold preservation (3-6 DEG C) 24 hours, filter;
(6) filtrate adds above-mentioned Fructus Amomi fine powder, stirs thereupon, and regulates pH4.5-6.0, add water and be adjusted to 800ml, and filter, sterilizing, to obtain final product.
5. the Chinese medicine composition of the treatment infantile constipation as described in claim as arbitrary in claim 1-3, is characterized in that described Chinese medicine composition can be pill, capsule, granule, powder or oral liquid.
6. the application of the Chinese medicine composition as described in claim as arbitrary in claim 1-3 in treatment infantile constipation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510871412.7A CN105412782A (en) | 2015-12-02 | 2015-12-02 | Traditional Chinese medicine composition for treating infantile constipation and preparation method thereof |
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| CN201510871412.7A CN105412782A (en) | 2015-12-02 | 2015-12-02 | Traditional Chinese medicine composition for treating infantile constipation and preparation method thereof |
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Citations (3)
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|---|---|---|---|---|
| CN101036718A (en) * | 2007-04-16 | 2007-09-19 | 左耀武 | External emplastrum for curing food retention in child stomach and the preparing method |
| CN103948718A (en) * | 2014-05-28 | 2014-07-30 | 滨州医学院附属医院 | Traditional Chinese medicament for treating pruritus vulvae of patient with gestational diabetes and preparation method thereof |
| CN104489166A (en) * | 2014-11-26 | 2015-04-08 | 山东永泰化工有限公司 | Health-care tea used for anxiety |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101036718A (en) * | 2007-04-16 | 2007-09-19 | 左耀武 | External emplastrum for curing food retention in child stomach and the preparing method |
| CN103948718A (en) * | 2014-05-28 | 2014-07-30 | 滨州医学院附属医院 | Traditional Chinese medicament for treating pruritus vulvae of patient with gestational diabetes and preparation method thereof |
| CN104489166A (en) * | 2014-11-26 | 2015-04-08 | 山东永泰化工有限公司 | Health-care tea used for anxiety |
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| 李丽等: "《三代世医宗修英医案话集》", 31 January 2014, 中国中医药出版社 * |
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