CN105411665B - A kind of cryosurgery system - Google Patents
A kind of cryosurgery system Download PDFInfo
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- CN105411665B CN105411665B CN201510920782.5A CN201510920782A CN105411665B CN 105411665 B CN105411665 B CN 105411665B CN 201510920782 A CN201510920782 A CN 201510920782A CN 105411665 B CN105411665 B CN 105411665B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
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Abstract
The invention discloses a kind of cryosurgery system, belong to technical field of medical equipment.The system includes surgery systems controller, freezer unit and gas pressurized device；The waste gas exhaust pipe of freezer unit is connected by the air inlet of exhaust gas recycling tube and gas pressurized device, and the gas outlet of gas pressurized device is connected with the air inlet of surgery systems controller, and the gas outlet of surgery systems controller and the air inlet of freezer unit connect.Cryosurgery system provided by the invention, low-pressure gas after freezer unit throttling acting is conveyed to by gas pressurized device by exhaust gas recycling tube, low-pressure gas is set to be pressurized to the gas pressure available for freezer unit work, resupply surgery systems controller, it is achieved thereby that the circulating repetition of gas utilizes, the consumption of gas is significantly reduced, is effectively improved freezer unit pressure difference, realizes preferably throttling refrigerating effect.
Description
Technical field
The present invention relates to technical field of medical equipment, more particularly to a kind of cryosurgery system.
Background technology
Cryosurgery system is a kind of Medical Devices of minimally invasive superfreeze ablated tumor, because it uses argon gas and helium
Gas is as refrigerant, therefore also referred to as argon helium knife.The cryosurgery system is mainly by surgery systems controller, freezer unit (freezing
Probe), high-pressure air source (argon gas and helium) and corresponding accessory structure composition, have superfreeze, insertion thermotherapy concurrently, immune increase
It is strong to wait multiple therapeutic effects.It emphasize it is minimally invasive, target and wipe out tumour, can be accurately positioned and accurately destroy cancerous tissue and
Normal structure is protected to greatest extent, and effective treatment method is provided for rapid tumour and the elimination tumor load killed.
In cryosurgery system, freezer unit is a hollow stainless steel probe, and probe interior is recycled high normal pressure and temperature
Argon gas (being used to freeze) or high normal pressure and temperature helium (being used to heat).High pressure argon gas rapid expansion inside probe pinpoint can freeze (burnt
Ear-Thomson effect), pathological tissues were freezed in tens seconds to less than -100 DEG C.High-pressure helium is rapidly swollen inside probe pinpoint
It is swollen to heat, quick pathological tissues of the heating in icing condition, make its cell rupture, reach the purpose of rapid inactivation.It is each
Kind gas has different pressure and temperature values, and its temperature when carrying out Joule-Thomson expansion can be made to keep constant, this temperature
It is referred to as reversal temperature.For certain gas, its temperature rises or falls original depending on it behind Joule-Thomson hole
Temperature is higher or lower than its reversal temperature.In general, if reversal temperature is higher than environment temperature, gas temperature will decline, example
Such as argon gas；Vice versa.
Fig. 1 shows the composition principle schematic diagram of existing cryosurgery system, and its operation principle is：Argon gas is first from argon
Gas cylinder 32 (full bottle gas pressure is about 5000psi) passes through argon gas pressure regulator valve 31, and pressure is dropped into 3000psi, passes through argon gas
Appendix 35 delivers to the air inlet of surgery systems controller；After surgery systems controller realizes various control functions, pass through electromagnetism
Valve control argon gas reaches gas outlet, and freezer unit 37 is reached by freezer unit appendix 39；Freezer unit 37 is produced by way of throttling
Low temperature is given birth to, then gas is directly discharged to air by freezer unit waste gas exhaust pipe 38, so as to complete refrigerating process.Similarly, when
When being operated in heating process, helium passes through helium pressure regulator valve 33 by helium tank 34 (full bottle gas pressure is about 2000psi), will
Pressure drops to 1000psi, and the air inlet of surgery systems controller is delivered to by helium appendix 36；Surgery systems controller passes through
Solenoid valve control helium reaches gas outlet, and freezer unit 37 is reached by freezer unit appendix 39；The side that freezer unit 37 passes through throttling
Formula produces heating, and then gas is directly discharged into air by freezer unit waste gas exhaust pipe 38, so as to complete heating process.Generally
At least to prepare two bottles of argon gas and one bottle of helium before the start of the surgery；When argon gas storage pressure is less than 3000psi or helium gas cylinder
Pressure can not be further continued for using, it is necessary to the full bottle gases at high pressure more renewed less than 1000psi.
But existing cryosurgery system has the following disadvantages in actual applications, is embodied in：
1) because surgical procedure needs to consume substantial amounts of argon gas and helium, therefore need to prepare sufficient high pressure before surgery
Argon gas and helium, it will certainly so increase operation cost.Security risk be present in high pressure argon gas and helium, this can to high pressure argon gas and
The transport of helium and hospital's storage tape carry out very big not convenient property.Argon gas and helium are resources-type rare gas, in freezer unit
Argon gas and helium are disposably released in air after throttling workmanship, are unfavorable for economizing on resources and environmentally friendly.
2) in use, because throttle orifice one end inside freezer unit passes through freezer unit waste gas exhaust pipe and air company
It is logical, it is therefore desirable to improve the operating pressure of freezer unit input argon gas to ensure the pressure differential at throttle orifice both ends so that freezer unit is real
Existing lower temperature.When argon gas storage pressure is less than 3000psi or helium storage pressure is less than 1000psi, refrigeration and heating
Effect can not meet needs of performing the operation, and must now change source of the gas, nonetheless its refrigeration is not also very good, can also
Cause the waste of residual gas in gas cylinder.
3) it is difficult to find suitable high pressure argon gas and helium supplier for some remote or profit of having inconvenient traffic areas, causes
Such operation is set not carry out.
The content of the invention
In order to solve existing cryosurgery system using cold media gas existing for process (argon gas and helium) consumption is big, system
The problems such as cold effect is undesirable, easily causes waste, and storage transport is risky, high-pressure air source lacks, the invention provides one
Kind cryosurgery system, including surgery systems controller, freezer unit and gas pressurized device；The waste gas exhaust pipe of the freezer unit
It is connected by exhaust gas recycling tube with the air inlet of the gas pressurized device, the gas outlet of the gas pressurized device and the hand
The air inlet connection of art system controller, the gas outlet of the surgery systems controller is connected with the air inlet of the freezer unit.
The gas pressurized device includes boost controller, the first compress cell, the second compress cell and exhaust unit；Institute
The arrival end for stating the first compress cell, the second compress cell and exhaust unit is connected with the exhaust gas recycling tube respectively, and described
Air inlet of the port of export of one compress cell and the second compress cell respectively with the surgery systems controller is connected；The discharge
The port of export connection air of unit；The boost controller electrically connects with the surgery systems controller.
First compress cell include the first valve, first gas detector, the first measuring transducer, the first gas cylinder,
Second valve, the first booster pump, the first gs-oil separator, the 3rd valve, heat exchanger, the second gas cylinder, the second measuring transducer,
First pressure regulator and the 4th valve；The arrival end of first valve is connected with the exhaust gas recycling tube, first valve
The port of export is connected with the air inlet of first gas cylinder, and the gas outlet of first gas cylinder and the arrival end of second valve connect
Connect, the port of export of second valve is connected with the entrance of first booster pump, the outlet and first of first booster pump
The entrance connection of gs-oil separator, the outlet of first gs-oil separator is connected with the arrival end of the 3rd valve, described
The port of export of 3rd valve is connected by the heat exchanger with the air inlet of second gas cylinder, the outlet of second gas cylinder
Mouth is connected with the entrance of the first pressure regulator, and the outlet of first pressure regulator is connected with the arrival end of the 4th valve, described
The port of export of 4th valve is connected with the air inlet of the surgery systems controller, first measuring transducer and described first
The air inlet connection of gas cylinder, second measuring transducer are connected with the gas outlet of second gas cylinder, the first gas inspection
Device is surveyed to be connected with the arrival end of the first valve.
Second compress cell include the 5th valve, second gas detector, the 3rd measuring transducer, the 3rd gas cylinder,
6th valve, the second booster pump, the second gs-oil separator, the 7th valve, the 4th gas cylinder, the 4th measuring transducer, the second pressure regulation
Device and the 8th valve；The arrival end of 5th valve is connected with the exhaust gas recycling tube, the port of export of the 5th valve with
The air inlet connection of 3rd gas cylinder, the gas outlet of the 3rd gas cylinder is connected with the arrival end of the 6th valve, described
The port of export of 6th valve is connected with the entrance of second booster pump, outlet and the second Oil-gas Separation of second booster pump
The entrance connection of device, the outlet of second gs-oil separator are connected with the arrival end of the 7th valve, the 7th valve
The port of export be connected with the air inlet of the 4th gas cylinder, the gas outlet of the 4th gas cylinder and the entrance of the second pressure regulator connect
Connect, the outlet of second pressure regulator is connected with the arrival end of the 8th valve, the port of export of the 8th valve with it is described
The air inlet connection of surgery systems controller, the 3rd measuring transducer is connected with the air inlet of the 3rd gas cylinder, described
4th measuring transducer is connected with the gas outlet of the 4th gas cylinder, the arrival end of the second gas detector and the 5th valve
Connection.
The exhaust unit includes the 9th valve, the first deflation muffler, the tenth valve and the second deflation muffler；It is described
The arrival end of 9th valve is connected with the exhaust gas recycling tube, the port of export and the first deflation muffler of the 9th valve
Air is connected after connection；The arrival end of tenth valve is connected with the exhaust gas recycling tube, the port of export of the tenth valve
Air is connected after being connected with the second deflation muffler.
First valve, the second valve, the 3rd valve and the 4th valve are magnetic valve；First measuring transducer
It is gas pressure transmitter with the second measuring transducer；First gs-oil separator is molecular-sieve type filter；Described
One booster pump is multi-stag booster pump.
5th valve, the 6th valve, the 7th valve and the 8th valve are magnetic valve；3rd measuring transducer
It is gas pressure transmitter with the 4th measuring transducer；Second gs-oil separator is molecular-sieve type filter；Described
Two booster pumps are multi-stag booster pump.
9th valve and the tenth valve are magnetic valve.
The appearance of second gas cylinder is provided with insulation cotton, or/and second gas cylinder is internally provided with cooling
Coil pipe.
The appearance of 4th gas cylinder is provided with insulation cotton, or/and the 4th gas cylinder is internally provided with heating
Coil pipe.
Cryosurgery system provided by the invention, it is by exhaust gas recycling tube that the low-pressure gas after freezer unit throttling acting is defeated
Gas pressurized device is given, low-pressure gas is pressurized to the gas pressure available for freezer unit work, resupplies surgery systems control
Device processed, it is achieved thereby that the circulating repetition of gas utilizes, the consumption of gas is significantly reduced, is effectively improved freezer unit
Pressure difference, realize preferably throttling refrigerating effect.
Brief description of the drawings
Fig. 1 is the composition principle schematic diagram of existing cryosurgery system；
Fig. 2 is cryosurgery system principle diagram provided in an embodiment of the present invention；
Fig. 3 is the technological principle schematic diagram of the cryosurgery system shown in Fig. 2.
Embodiment
With reference to the accompanying drawings and examples, technical solution of the present invention is further described.
Fig. 2 is cryosurgery system principle diagram provided in an embodiment of the present invention, the system include surgery systems controller,
Freezer unit and gas pressurized device.Wherein, the waste gas exhaust pipe of freezer unit entering by exhaust gas recycling tube and gas pressurized device
Gas port is connected, and the gas outlet of gas pressurized device is connected with the air inlet of surgery systems controller, and surgery systems controller goes out
The air inlet of gas port and freezer unit connects.
Fig. 3 is the technological principle schematic diagram of the cryosurgery system shown in Fig. 2.Freezer unit 1 and surgery systems controller 2
26S Proteasome Structure and Function is same as the prior art, and the embodiment of the present invention repeats no more.Gas pressurized device 23 includes helium high pressure gas
Bottle 3, argon gas gas cylinder 4, argon gas low pressure gas cylinder 5, helium low pressure gas cylinder 6, argon gas booster pump 7, helium booster pump 8, helium go out
Gas main valve 9, argon gas outlet main valve 10, argon inlet main valve 11, argon gas vent valve 12, helium air inlet main valve 13, helium high pressure gas
Bottle pressure transmitter 14, argon gas gas cylinder pressure transmitter 15, argon gas low pressure gas cylinder pressure transmitter 16, deflation muffler
17th, helium low pressure gas cylinder pressure transmitter 18, high-pressure helium intake valve 19, high pressure argon gas intake valve 20, low-pressure argon air outlet valve
21st, low pressure helium air outlet valve 22, exhaust gas recycling tube 24, argon gas detector 25, helium atmosphere detector 26, helium oil gas point
From device 27, argon gas gs-oil separator 28, helium pressure regulator 29, argon gas pressure regulator 30, helium vent valve 31, deflation muffler 32,
Boost controller 33 and heat exchanger 34.Argon gas gas cylinder 4, argon gas low pressure gas cylinder 5, argon gas booster pump 7, argon gas Oil-gas Separation
Device 28, heat exchanger 34, argon gas outlet main valve 10, argon inlet main valve 11, argon gas gas cylinder pressure transmitter 15, argon gas are low
Air bottle pressure transmitter 16, high pressure argon gas intake valve 20, low-pressure argon air outlet valve 21, argon gas detector 25 and argon gas are adjusted
Depressor 30 constitutes argon gas compress cell.Helium gas cylinder 3, helium low pressure gas cylinder 6, helium booster pump 8, helium outlet main valve
9th, helium air inlet main valve 13, helium gas cylinder pressure transmitter 14, helium low pressure gas cylinder pressure transmitter 18, high-pressure helium enter
Air valve 19, low pressure helium air outlet valve 22, helium atmosphere detector 26, helium gs-oil separator 27 and helium pressure regulator 29 constitute
Helium compress cell.It is single that argon gas vent valve 12, helium vent valve 31, deflation muffler 17 and deflation muffler 32 constitute discharge
Member.Boost controller 33 electrically connects with surgery systems controller 2.
Referring to Fig. 3, the waste gas exhaust pipe (not shown) of freezer unit 1 is connected with one end of exhaust gas recycling tube 24, argon inlet
Main valve 11, argon gas vent valve 12, helium air inlet main valve 13 and helium vent valve 31 arrival end respectively with exhaust gas recycling tube 24
The other end connects；The port of export of argon gas vent valve 12 connects air after being connected with deflation muffler 17；Helium vent valve 31 goes out
Mouth end connects air after being connected with deflation muffler 32；The port of export of argon inlet main valve 11 and the air inlet of argon gas low pressure gas cylinder 5
Mouth connection, the gas outlet of argon gas low pressure gas cylinder 5 are connected with the arrival end of low-pressure argon air outlet valve 21, low-pressure argon air outlet valve 21
The port of export is connected with the entrance of argon gas booster pump 7, and the outlet of argon gas booster pump 7 is connected with the entrance of argon gas gs-oil separator 28,
The outlet of argon gas gs-oil separator 28 is connected with the arrival end of high pressure argon gas intake valve 20, the port of export of high pressure argon gas intake valve 20
It is connected by heat exchanger 34 with the air inlet of argon gas gas cylinder 4, gas outlet and the argon gas pressure regulator 30 of argon gas gas cylinder 4
Entrance connection, the outlet of argon gas pressure regulator 30 is connected with the arrival end of argon gas outlet main valve 10, and argon gas outlet main valve 10 goes out
Mouth end is connected with the air inlet of surgery systems controller 2, and argon gas low pressure gas cylinder pressure transmitter 16 enters with argon gas low pressure gas cylinder 5
Gas port is connected, and argon gas gas cylinder pressure transmitter 15 is connected with the gas outlet of argon gas gas cylinder 4, argon gas detector 25
It is connected with the arrival end of argon inlet main valve 11；The port of export of helium air inlet main valve 13 connects with the air inlet of helium low pressure gas cylinder 6
Connect, the gas outlet of helium low pressure gas cylinder 6 is connected with the arrival end of low pressure helium air outlet valve 22, the outlet of low pressure helium air outlet valve 22
End is connected with the entrance of helium booster pump 8, and the outlet of helium booster pump 8 is connected with the entrance of helium gs-oil separator 27, helium
The outlet of gs-oil separator 27 is connected with the arrival end of high-pressure helium intake valve 19, the port of export and helium of high-pressure helium intake valve 19
The air inlet connection of gas gas cylinder 3, the gas outlet of helium gas cylinder 3 are connected with the entrance of helium pressure regulator 29, and helium is adjusted
The outlet of depressor 29 is connected with the arrival end of helium outlet main valve 9, the port of export and the surgery systems controller of helium outlet main valve 9
2 air inlet connection, helium low pressure gas cylinder pressure transmitter 18 are connected with the air inlet of helium low pressure gas cylinder 6, helium high pressure gas
Bottle pressure transmitter 14 is connected with the gas outlet of helium gas cylinder 3, helium atmosphere detector 26 and helium air inlet main valve 13
Arrival end connects.
In actual applications, helium gas cylinder and argon gas gas cylinder are two less gas cylinders of volume, are respectively used to
Store high-pressure helium (pressure is about 1500psi) and high pressure argon gas (pressure is about 4500psi).Such as：Helium high pressure gas
The volume of bottle is 5 liters, safe pressure 1800psi；The volume of argon gas gas cylinder is 10 liters, safe pressure 5000psi.Argon
Gas low pressure gas cylinder and helium low pressure gas cylinder are two less gas cylinders of volume, are respectively used to the low-pressure argon and low that storage recovery comes
Helium is pressed, respectively as argon gas booster pump and the input gas buffer of helium booster pump.Such as：The volume of argon gas low pressure gas cylinder is
20 liters, safe pressure 150psi；The volume of helium low pressure gas cylinder is 10 liters, safe pressure 150psi.Due to whole operation
The gas flow that system needs is little, therefore argon gas booster pump and helium booster pump can be realized using multi-stag booster pump,
This booster pump small volume, noise are low, and the fixing fabric structure of gas pressurized device can be made to be moved easily fortune within a cubic meter
It is defeated.Argon gas booster pump is pressurized to 4500psi by next low-pressure argon is reclaimed.Helium booster pump will reclaim the low pressure helium supercharging come
To 1500psi.Helium gas cylinder pressure transmitter, argon gas gas cylinder pressure transmitter, argon gas low pressure gas cylinder pressure inverting
Device, helium low pressure gas cylinder pressure transmitter are used for the pressure for monitoring each gas cylinder in real time respectively.Helium pressure regulator is by helium pressure
Exported after being adjusted to 1000psi to surgery systems controller.Argon gas pressure regulator by argon pressure be adjusted to export after 3000psi to
Surgery systems controller.Argon gas detector is used to detect purity of argon, and helium atmosphere detector is used to detect helium purity.
Helium gs-oil separator and argon gas gs-oil separator are used to remove caused a small amount of oil gas in pressurization, to prevent oil gas from existing
Condensed at the throttle orifice of freezer unit, block throttle orifice, ensure freezer unit normal work.Helium gs-oil separator and argon gas oil gas point
Molecular-sieve type filter can be selected from device.Helium outlet main valve, argon gas outlet main valve, argon inlet main valve, argon gas vent valve,
Helium vent valve, helium air inlet main valve, high-pressure helium intake valve, high pressure argon gas intake valve, low-pressure argon air outlet valve and low pressure helium
Gas air outlet valve is magnetic valve.When the cryosurgery system of the embodiment of the present invention does not work, above-mentioned all magnetic valves are in
Closed mode, it can be stored for a long time with the gases at high pressure ensured in helium gas cylinder and argon gas gas cylinder.Helium high pressure gas
Bottle pressure transmitter, argon gas gas cylinder pressure transmitter, argon gas low pressure gas cylinder pressure transmitter, helium low pressure gas cylinder pressure become
Send device, argon gas detector and helium atmosphere detector that the signal of detection is sent into boost controller in real time respectively, be pressurized
Controller acts on the mutual cooperation of surgery systems controller, and is sent by boost controller for controlling magnetic valve and booster pump
Signal, to control unlatching/closing of magnetic valve and booster pump.The implementation of boost controller in petrochemical industry
Have a wide range of applications, be known to the skilled person general knowledge, therefore the embodiment of the present invention is to boost controller
Realize that circuit is not elaborated.
Referring to Fig. 3, the working method of cryosurgery system provided in an embodiment of the present invention is as follows：
1) when surgical procedure needs freezing, argon gas outlet main valve 10 is opened, argon gas is entered surgery systems controller 2,
By entering freezer unit 1 after its control, low temperature is produced by throttling to do work, the argon gas after throttling is inputted by exhaust gas recycling tube 24
Gas pressurized device 23；The purity of the argon gas of the detection backflow of argon gas detector 25, if purity of argon is not up to 99%, argon
Gas vent valve 12 is opened, and the impure argon gas of backflow is bled off；When purity of argon reaches more than 99%, argon gas vent valve 12 closes
Close, argon inlet main valve 11 is opened, and is started to the gas transmission of argon gas low pressure gas cylinder 5；When the pressure of argon gas gas cylinder 4 is less than a certain pre-
Limit value (such as：When 3000psi), or when the pressure of argon gas low pressure gas cylinder 5 is higher than a certain pre-set limit (such as：50psi),
Argon gas booster pump 7 starts, and the argon gas reclaimed in argon gas low pressure gas cylinder 5 is pressurized, and the argon gas that argon gas booster pump 7 exports passes through argon gas
Heat exchanger 34 is transported to after gs-oil separator removal oil gas to cool down, the argon gas of cooling is transported to argon gas gas cylinder 4, and passes through
Supply surgery systems after pressure is limited to 3000psi by argon gas pressure regulator 30 are crossed to use；When the pressure of argon gas gas cylinder 4 is higher than
A certain pre-set limit (such as：When 4500psi), or argon gas low pressure gas cylinder 5 pressure less than a certain pre-set limit (such as：5psi)
When, argon gas booster pump 7 stops, but the high pressure argon gas stored in argon gas gas cylinder 4 is continued to output to meet the work of freezer unit 1
Make, until the pressure of argon gas gas cylinder and argon gas low pressure gas cylinder meets argon gas booster pump entry condition, argon gas supercharging pump startup.
So, recycling for argon gas is completed.
2) when surgical procedure needs heating, all magnetic valves in argon gas gas circuit is closed, helium outlet main valve 9 is opened, makes
Helium enters surgery systems controller 2, by entering freezer unit 1 after its control, produces warming phenomenon by throttling to do work, throttling
Helium afterwards inputs gas pressurized device 23 by exhaust gas recycling tube 24；Helium atmosphere detector 26 detects the pure of the helium of backflow
Degree, if helium purity is not up to 99%, helium vent valve 31 is opened, and the impure helium of backflow is bled off；When helium purity
When reaching more than 99%, helium vent valve 31 is closed, and helium air inlet main valve 13 is opened, and is started to the gas transmission of helium low pressure gas cylinder 6；When
The pressure of helium gas cylinder 3 less than a certain pre-set limit (such as：When 1000psi), or the pressure of helium low pressure gas cylinder 6 is higher than
A certain pre-set limit (such as：When 50psi), helium booster pump 8 starts, and the helium reclaimed in helium low pressure gas cylinder 6 is pressurized, helium
The helium that gas booster pump 8 exports is transported to helium gas cylinder 3 after helium gs-oil separator 27 removes oil gas, and passes through
Pressure is limited to after 1000psi and supplies surgery systems use by helium pressure regulator 29；When the pressure of helium gas cylinder 3 is higher than certain
One pre-set limit (such as：When 1500psi), or helium low pressure gas cylinder 6 pressure less than a certain pre-set limit (such as：5psi)
When, helium booster pump 8 stops, but the high-pressure helium stored in helium gas cylinder 3 is continued to output to meet the work of freezer unit 1
Until the pressure of helium gas cylinder and helium low pressure gas cylinder meets helium booster pump entry condition, helium supercharging pump startup.This
Sample, complete recycling for helium.
It should be noted that：Usual cryoablation operation needs first to be freezed, and carries out heat temperature raising again afterwards, so
Optimal inactivating efficacy can be reached.When freezing switches to heating, and heating switches to freezing, being required to will be few in freezer unit
The mixed gas of amount is bled off；When starting new operation every time simultaneously, meeting residual fraction air, all new beginnings in new freezer unit
Operation also to bleed off a part of mixed gas after could start to reclaim.By the purity of detector detection gas, bleed off
Impure gas, the high gas of recovery purity, the only a small amount impure gas that so whole surgical procedure wastes, and big portion absolutely
Divide high-purity gas to be recovered supercharging to reuse.
With the increase of access times, the gas pressure meeting being stored in advance in helium gas cylinder and argon gas gas cylinder
Decline.The pressure of helium gas cylinder and argon gas gas cylinder can pass through helium gas cylinder pressure transmitter and argon gas high pressure gas
Bottle pressure transmitter is monitored；When pressure less than a certain pre-set limit (such as：Argon gas is less than 3000psi, and helium is less than
When 1000psi), new operation cannot be carried out again and circulated, it is necessary to the helium gas cylinder and argon gas high pressure in system
Gas cylinder is inflated.Helium and argon gas can be inflated to respectively by low pressure gas cylinder by exhaust gas recycling tube during inflation, then pass through supercharging
Pump pressure contracting is stored in gas cylinder.It is so very low to the pressure requirements of outside source of inflation gas, it may not be necessary to it is high-pressure air source, from
And the gas in external air source can be made full use of.
Cryosurgery system provided in an embodiment of the present invention, due to there is the presence of booster pump, therefore can be by rationally setting
The working time of two booster pumps, so that two low pressure gas cylinders and exhaust gas recycling tube are in less than one standard atmospheric pressure and worked
State, the gas input of such freezer unit and the pressure difference of waste gas discharge end are bigger.Can by the principle of Joule-Thomson effect
Know, pressure difference is one of freezing or the most important influence factor of heating effect, and the bigger effect of pressure difference is better.The embodiment of the present invention provides
Cryosurgery system, can not only save gas, but also can realize preferably freezing and heating effect.
Cryosurgery system provided in an embodiment of the present invention is closed circulatory system.When system carries out refrigeration operation,
After supercharging, the temperature of argon gas can rise the argon gas that recovery comes, and argon gas is cooled down by heat exchanger, makes the temperature of argon gas
Degree further reduces, and so with the circulation work of system, the temperature of argon gas stored in argon gas gas cylinder can be more and more lower；By
The principle of Joule-Thomson effect understands that the gas temperature before freezer unit argon gas throttling workmanship is lower, the gas after freezer unit throttling
Temperature can be lower.Furthermore it is also possible to (such as add thermal insulation separation in gas cylinder appearance by doing insulation processing to argon gas gas cylinder
Hot cotton), it is more preferable to obtain so as to ensure the low-temperature condition of argon gas further to separate low temperature argon gas and extraneous heat exchange
Refrigerating effect；At the same time it can also be based on the more preferable mixed gas of Joule-Thomson effect throttling refrigeration effect using other
(such as：Nitrogen, oxygen, the mixed gas of neon and argon gas composition) argon gas is replaced, to obtain more preferable refrigeration.Need
To illustrate that：For the cooling treatment of the argon gas after supercharging, in addition to using the heat exchanger of the present embodiment, can also adopt
With other types of cooling, such as：Cooling coil is set in argon gas gas cylinder, or in booster pump outlet to argon gas high pressure gas
Cooling adjoining pipe is set on the pipeline of bottle；Certainly the above-mentioned various types of cooling can be also applied in combination, to reach optimal refrigeration
Effect.Similarly, the helium come is reclaimed after supercharging, and the temperature of helium can rise, so with the circulation work of system, helium
The helium temperature meeting more and more higher stored in gas cylinder, this can greatly improve the heating effect of operation heating process；In addition, also
Can be by doing insulation processing (such as adding insulation cotton in gas cylinder appearance) to helium gas cylinder, further to separate height
Warm helium and extraneous heat exchange, so as to ensure the condition of high temperature of helium, to obtain more preferable heating effect.In order to further
The temperature of the helium after supercharging is improved, heating coil can be set in helium gas cylinder, or in booster pump outlet to helium
Heating adjoining pipe is set on the pipeline of gas gas cylinder；Certainly above-mentioned various mode of heatings can be also applied in combination, to reach most
Good heating effect.
Compared with existing cryosurgery system, the embodiment of the present invention has the following advantages that：
1) gas pressurized device of the embodiment of the present invention, the consumption of gas is significantly reduced；In surgical procedure, only
Need to bleed off few a part of impure gas in argon gas and helium switch operating, gas consumption is extremely low.
2) embodiment of the present invention uses the gas circulating of closed loop, realizes closed loop cycle throttling refrigeration.Operation every time
High pressure argon gas and helium gas cylinder need not be specially equipped with, as long as normal power supply can work, greatly increases the facility used
Property.
3) system of the embodiment of the present invention is stored with appropriate refrigerant (argon gas and helium) in itself, can be relatively from far-off regions
Carry out the operation of this class, and the pressure requirements to supplementing source of the gas are extremely low, economize on resources and environmentally friendly.
4) embodiment of the present invention can realize that recovery passage is less than a standard atmospheric pressure by booster pump, drastically increase
Freezer unit pressure difference, realize preferably throttling refrigerating effect.Furthermore it is also possible to by the composition in system of the embodiment of the present invention
Appropriate heat-insulated processing is done in part, the gas temperature for being conveyed to freezer unit is further reduced, so as to realize more preferable refrigerating effect；
At the same time it can also by using different types of refrigerant, to obtain more preferable refrigerating effect.
Particular embodiments described above, the purpose of the present invention, technical scheme and beneficial effect are carried out further in detail
Describe in detail it is bright, should be understood that the foregoing is only the present invention specific embodiment, be not intended to limit the invention, it is all
Within the spirit and principles in the present invention, any modification, equivalent substitution and improvements done etc., it should be included in the guarantor of the present invention
Within the scope of shield.
Claims (8)
1. a kind of cryosurgery system, it is characterised in that including surgery systems controller, freezer unit and gas pressurized device；Institute
The waste gas exhaust pipe for stating freezer unit is connected by exhaust gas recycling tube with the air inlet of the gas pressurized device, the gas boosting
The gas outlet of device is connected with the air inlet of the surgery systems controller, the gas outlet of the surgery systems controller with it is described
The air inlet connection of freezer unit；
The gas pressurized device includes boost controller, the first compress cell, the second compress cell and exhaust unit；Described
The arrival end of one compress cell, the second compress cell and exhaust unit is connected with the exhaust gas recycling tube respectively, and described first increases
Air inlet of the port of export of pressure unit and the second compress cell respectively with the surgery systems controller is connected；The exhaust unit
The port of export connection air；The boost controller electrically connects with the surgery systems controller；
First compress cell includes the first valve, first gas detector, the first measuring transducer, the first gas cylinder, second
Valve, the first booster pump, the first gs-oil separator, the 3rd valve, heat exchanger, the second gas cylinder, the second measuring transducer, first
Pressure regulator and the 4th valve；The arrival end of first valve is connected with the exhaust gas recycling tube, the outlet of first valve
End is connected with the air inlet of first gas cylinder, and the gas outlet of first gas cylinder is connected with the arrival end of second valve,
The port of export of second valve is connected with the entrance of first booster pump, outlet and the first oil gas of first booster pump
The entrance connection of separator, the outlet of first gs-oil separator are connected with the arrival end of the 3rd valve, and the described 3rd
The port of export of valve is connected by the heat exchanger with the air inlet of second gas cylinder, the gas outlet of second gas cylinder with
The entrance connection of first pressure regulator, the outlet of first pressure regulator are connected with the arrival end of the 4th valve, and the described 4th
The port of export of valve is connected with the air inlet of the surgery systems controller, first measuring transducer and first gas cylinder
Air inlet connection, second measuring transducer is connected with the gas outlet of second gas cylinder, the first gas detector
It is connected with the arrival end of the first valve.
2. cryosurgery system as claimed in claim 1, it is characterised in that second compress cell include the 5th valve,
Second gas detector, the 3rd measuring transducer, the 3rd gas cylinder, the 6th valve, the second booster pump, the second gs-oil separator,
Seven valves, the 4th gas cylinder, the 4th measuring transducer, the second pressure regulator and the 8th valve；The arrival end of 5th valve and institute
Exhaust gas recycling tube connection is stated, the port of export of the 5th valve is connected with the air inlet of the 3rd gas cylinder, the 3rd gas cylinder
Gas outlet be connected with the arrival end of the 6th valve, the port of export of the 6th valve and the entrance of second booster pump
Connection, the outlet of second booster pump are connected with the entrance of the second gs-oil separator, the outlet of second gs-oil separator
It is connected with the arrival end of the 7th valve, the port of export of the 7th valve is connected with the air inlet of the 4th gas cylinder, institute
The gas outlet for stating the 4th gas cylinder is connected with the entrance of the second pressure regulator, outlet and the 8th valve of second pressure regulator
Arrival end is connected, and the port of export of the 8th valve is connected with the air inlet of the surgery systems controller, the 3rd measurement
Transmitter is connected with the air inlet of the 3rd gas cylinder, and the gas outlet of the 4th measuring transducer and the 4th gas cylinder connects
Connect, the second gas detector is connected with the arrival end of the 5th valve.
3. cryosurgery system as claimed in claim 1, it is characterised in that the exhaust unit includes the 9th valve, first
Deflation muffler, the tenth valve and the second deflation muffler；The arrival end of 9th valve is connected with the exhaust gas recycling tube,
The port of export of 9th valve connects air after being connected with the first deflation muffler；The arrival end of tenth valve with
Exhaust gas recycling tube connection, the port of export of the tenth valve connect air after being connected with the second deflation muffler.
4. cryosurgery system as claimed in claim 1, it is characterised in that first valve, the second valve, the 3rd valve
It is magnetic valve with the 4th valve；First measuring transducer and the second measuring transducer are gas pressure transmitter；Institute
It is molecular-sieve type filter to state the first gs-oil separator；First booster pump is multi-stag booster pump.
5. cryosurgery system as claimed in claim 2, it is characterised in that the 5th valve, the 6th valve, the 7th valve
It is magnetic valve with the 8th valve；3rd measuring transducer and the 4th measuring transducer are gas pressure transmitter；Institute
It is molecular-sieve type filter to state the second gs-oil separator；Second booster pump is multi-stag booster pump.
6. cryosurgery system as claimed in claim 3, it is characterised in that the 9th valve and the tenth valve are electromagnetism
Valve.
7. cryosurgery system as claimed in claim 1, it is characterised in that the appearance of second gas cylinder is provided with thermal insulation separation
Hot cotton, or/and second gas cylinder are internally provided with cooling coil.
8. cryosurgery system as claimed in claim 2, it is characterised in that the appearance of the 4th gas cylinder is provided with thermal insulation separation
Hot cotton, or/and the 4th gas cylinder are internally provided with heating coil.
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| CN201510920782.5A CN105411665B (en) | 2015-12-11 | 2015-12-11 | A kind of cryosurgery system |
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| CN201510920782.5A CN105411665B (en) | 2015-12-11 | 2015-12-11 | A kind of cryosurgery system |
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| CN105411665B true CN105411665B (en) | 2017-12-12 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105902310B (en) * | 2016-04-11 | 2018-07-06 | 天津美电医疗科技有限公司 | Cryosurgery device for adjusting air pressure to realize freezing and rewarming |
| CN107951559A (en) * | 2018-01-05 | 2018-04-24 | 北京阳光易帮医疗科技有限公司 | A kind of cryosurgery system |
| CN114668481B (en) * | 2022-05-26 | 2023-01-24 | 上海导向医疗系统有限公司 | Dual-system cryotherapy system based on precooling of cryogenic refrigerator |
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| CN101584602A (en) * | 2008-05-20 | 2009-11-25 | 上海导向医疗系统有限公司 | Multi-stage precooling cryoablation method and equipment |
| WO2010007954A1 (en) * | 2008-07-15 | 2010-01-21 | 株式会社デージーエス・コンピュータ | Cryotherapy planning device and cryotherapy device |
| CN101732090A (en) * | 2009-11-10 | 2010-06-16 | 上海理工大学 | Cryoablation system with precooling device and control method thereof |
| CN104873265A (en) * | 2015-06-02 | 2015-09-02 | 北京迈迪顶峰医疗科技有限公司 | Freezing ablation system |
| CN205215352U (en) * | 2015-12-11 | 2016-05-11 | 北京阳光易帮医疗科技有限公司 | Low temperature surgical system |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101584602A (en) * | 2008-05-20 | 2009-11-25 | 上海导向医疗系统有限公司 | Multi-stage precooling cryoablation method and equipment |
| WO2010007954A1 (en) * | 2008-07-15 | 2010-01-21 | 株式会社デージーエス・コンピュータ | Cryotherapy planning device and cryotherapy device |
| CN101732090A (en) * | 2009-11-10 | 2010-06-16 | 上海理工大学 | Cryoablation system with precooling device and control method thereof |
| CN104873265A (en) * | 2015-06-02 | 2015-09-02 | 北京迈迪顶峰医疗科技有限公司 | Freezing ablation system |
| CN205215352U (en) * | 2015-12-11 | 2016-05-11 | 北京阳光易帮医疗科技有限公司 | Low temperature surgical system |
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