CN105395931A - Method for preparing healthcare nutritional porridge eaten by patient with coronary heart disease - Google Patents
Method for preparing healthcare nutritional porridge eaten by patient with coronary heart disease Download PDFInfo
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- CN105395931A CN105395931A CN201510851389.5A CN201510851389A CN105395931A CN 105395931 A CN105395931 A CN 105395931A CN 201510851389 A CN201510851389 A CN 201510851389A CN 105395931 A CN105395931 A CN 105395931A
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- porridge
- chinese medicine
- radix
- heart disease
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Abstract
The invention relates to a method for preparing healthcare nutritional porridge eaten by a patient with the coronary heart disease, and belongs to the technical field of food. The nutritional porridge is mainly prepared from polished round-grained rice and pueraria powder, then traditional Chinese medicine extract is added, and the traditional Chinese medicine extract is prepared from roots of red-rooted salvia, peach kernels, radix angelica sinensis, frankincense, safflowers, myrrh, radix scrophulariae, milkvetch roots, spina date seeds and pseudo-ginseng. The traditional Chinese medicine extract, polished round-grained rice and pueraria powder are boiled into raw porridge together, then saccharose, salt and other auxiliary materials are added, and the healthcare nutritional porridge with various tastes can be prepared. Powder porridge capable of being brewed can also be prepared through vacuum drying and other technologies, and then various packaging modes allowing the porridge to be convenient to carry and eat can be prepared through the modern universal food packaging technology. If the healthcare food is eaten frequently, the functions of prevention, healthcare and auxiliary therapy can be achieved for the patient with the coronary heart disease. Compared with the prior art, the daily healthcare and auxiliary therapy of the patient with the coronary heart disease are facilitated, and the porridge can be eaten by the patient for a long time.
Description
Technical field
The present invention relates to a kind of preparation of the health-care nutritive porridge supplying patients with coronary heart disease to eat, belong to food technology field.
Background technology
Medicated diet rises in the traditional diet of China and dietary therapy of Chinese medicine culture, medicated diet is under Chinese medicine, cookery and threpsology's theoretical direction, strictly press medicated food formula, by compatible for the food that Chinese medicine and some have medical value, adopt the ticbit with certain color, shape that the diet culinary art of China's uniqueness and modern scientific method are made.It is the product that the medical knowledge of Chinese tradition combines with cooking experience.Its " residence cure in food ", both using medicine as food, compose food with medicinal again, food power borrowed by medicine, and food helps medicine prestige, and the two complements each other, and brings out the best in each other; Both there is higher nutritive value, again preventable disease cure the disease, health body-building, life lengthening.
Coronary atherosclerotic heart disease is coronary artery generation atherosclerotic lesion and causes lumen of vessels stenosis or occlusion, causes myocardial ischemia, anoxia or downright bad and heart disease that is that cause, is usually called as " coronary heart disease ".But the scope of coronary heart disease may be more extensive, also comprises inflammation, thromboembolism etc. and cause luminal stenosis or obturation.Coronary heart disease is divided into 5 large classes by World Health Organization (WHO): silent ischemia (latent coronary heart disease), angina pectoris, myocardial infarction, ischemic heart failure (ischemic heart desease) and sudden death 5 kinds of Clinical types.Stable coronary heart disease and acute coronary syndrome is usually divided in clinical.
Coronary heart disease belongs to the thoracic obstruction, angina pectoris, the precordial pain with cold limbs category of the traditional Chinese medical science.Primary disease is often with hypertension, hyperlipemia, diabetes etc.Brain worker is common, large to health of people harm, is one of old people's underlying cause of death.
Chinese medicine thinks that coronary heart disease is the Primary Asthenia-Secondary Sthenia Syndrome of simulataneous insufficiency and excessive.Clinical manifestation has very big difference, depending on change of illness state when opinion is controlled with individual difference; Symptomatic treatment in acute condition, radical treatment in chronic case, or treating both the principal and the secondary aspects of a disease at the same time, make the sun in ambition unfold, and blood vessels run unimpeded.Effect a permanent cure and adopt the method for warming YANG and invigorating QI, nourishing YIN and benefiting blood; Take stopgap measures, with cold relieving, eliminating phlegm, the method such as to invigorate blood circulation.In a word, deficiency and excess be debated, bright specimen carries out tonify deficiency or removing the relative excess, or giving consideration to both the incidental and fundamental, carry out medicine typing treatment, just can obtain good effect.
This disease mostly is insufficiency of vital energy and blood, and negative and positive virtual loss, blood stasis due to qi deficiency, phlegm stagnation in collateral etc. cause.The common deficiency of clinical manifestation and deficient disease.Therefore, with benefiting vital QI and blood multiplex during treatment by Chinese herbs, nourishing YIN and invigorating YANG and so on rule is treated.Under " strengthening vital QI to eliminate pathogenic factors " principle instructs, first excise the factor of bringing out, increasing the weight of, the sufferer of radical cure itself.Eliminating evil with blood circulation promoting and blood stasis dispelling, warming and activating heart-YANG, eliminating phlegm dredging collateral, the chest stuffiness relieving of regulating the flow of vital energy, removing dampness dredging collateral, it is main for removing expectorant heat.
" drink trencherman, the lifeblood of people also ".The diet of science can not only prevent coronary heart disease, and can treat coronary heart disease to a certain extent, can also improve the prognosis of Coronary Heart Disease Patients, decides future and the destiny of patients with coronary heart disease to a great extent, prognosis and lapsing to.But the diet of science is unpractical concerning a lot of family, because this means that will pay a large amount of time, energy and material etc. goes to adjust diet.Health-care nutritive porridge of the present invention solves this problem just, and it both had nutrition health-care functions, facilitates edible for patients again.In the middle of the life that can better apply to patient, thus play important conditioning and health-care effect.
Summary of the invention
The technical problem to be solved in the present invention be exploitation a kind of applicable patients with coronary heart disease eat there is certain health care and the novel healthy food of therapeutic efficiency.For solving this technical problem, the technical scheme of inventor is, utilizes Semen oryzae sativae and powder of Radix Puerariae to be primary raw material, provides the condition of food nutrition, then add Chinese medicine extract, make the health-care nutritive porridge of instant edible.This Chinese medicine extract is the Chinese crude drug of well-chosen and compatibility, the prescription of its composition can form synergism with Semen oryzae sativae and powder of Radix Puerariae, while providing nutrient substance for patient, play certain conditioning, treatment and health-care effect, the rehabilitation for patient provides larger help.
The formula of health-care nutritive porridge of the present invention is (with parts by weight): Semen oryzae sativae 20-80 part, powder of Radix Puerariae 10-50 part, Chinese medicine extract 4-18 part; The wherein composition of Chinese medicine extract: Radix Salviae Miltiorrhizae 8-32 part, Semen Persicae 10-40 part, Radix Angelicae Sinensis 8-20 part, Olibanum 3-9 part, Flos Carthami 4-12 part, Myrrha 5-17 part, Radix Scrophulariae 6-19 part, Radix Astragali 7-24 part, Semen Ziziphi Spinosae 7-20 part, Radix Notoginseng 6-18 part.
Further, described health-care nutritive porridge raw material optimum ratio be (with parts by weight): Semen oryzae sativae 50 parts, powder of Radix Puerariae 25 parts, Chinese medicine extract 8 parts; The wherein composition of Chinese medicine extract: Radix Salviae Miltiorrhizae 20 parts, 25 parts, Semen Persicae, Radix Angelicae Sinensis 14 parts, Olibanum 6 parts, 8 parts, Flos Carthami, Myrrha 11 parts, Radix Scrophulariae 12 parts, the Radix Astragali 15 parts, Semen Ziziphi Spinosae 13 parts, Radix Notoginseng 12 parts.
The present invention also discloses a kind of preparation method of health-care nutritive porridge, comprises the following steps:
(1) various raw material is accurately taken by formula of the present invention;
(2) all Chinese crude drugs comprised by Chinese medicine extract add the purified water of initial medical material 5-15 times weight, soak 6-24 hour, backflow decocts 1-6 hour, filter, add the purified water of initial weight 4-12 times weight again, backflow decocts 1-5 hour, filters and retains filtering residue, merging filtrate, being concentrated into 60 DEG C of relative densities is that the concentrated solution of 1.15-1.18 is for subsequent use;
(3) filtering residue of step (2) is added the ethanol of the concentration 60-85% of 5-12 times of weight, reflux, extract, 2 times, each 1-6 hour, filter, merging filtrate, distilling under reduced pressure removing ethanol, and to be concentrated into 60 DEG C of relative densities be that the concentrated solution of 1.15-1.18 is for subsequent use;
(4) merged by the concentrated solution of step (2) and (3) gained, continuing to be concentrated into 60 DEG C of relative densities is the concentrated liquid of tradition Chinese medicine of 1.23-1.27, is Chinese medicine extract, for subsequent use;
(5) Semen oryzae sativae is added the water of 5-9 times of weight, boil 15-60 minute, water powder of Radix Puerariae being added 2-5 times of weight is modulated into pasty state, adds in Semen oryzae sativae medicated porridge; Taking Chinese medicine extract by formula proportion adds in Semen oryzae sativae medicated porridge; Stir, continue to boil 5-20 minute, be the raw material medicated porridge of nutrient porridge;
(6) in the raw material medicated porridge of step (5), the adjuvant such as sucrose, Sal is added, the health-care nutritive porridge of various taste can be made, also the powdery medicated porridge that can brew can be made by technology such as vacuum dryings, then utilize modern general Food Packaging technology to make and be variously convenient for carrying edible packaged form, as bowl medicated porridge, pop can, packed medicated porridge etc.
The packaged form of described health-care nutritive porridge can be a bowl medicated porridge, pop can or packed medicated porridge.
The present invention also discloses the purposes had in the novel healthy food of health care and therapeutic efficiency that above-mentioned health-care nutritive porridge is eating for patients with coronary heart disease.
The character Characteristic of health-care nutritive porridge of the present invention main raw material(s) used:
Semen oryzae sativae: Semen oryzae sativae is the one of rice, common staple food.All have cultivation all over China, existing more than 6900 year of plantation history is one of special product of Chinese food culture.Mainly originate in Northeast China.
Containing rich in protein in Semen oryzae sativae, the aminoacid of contained needed by human is also relatively more comprehensive, also containing the multiple nutritional components such as fat, calcium phosphorus, ferrum and vitamin B group.
Semen oryzae sativae has YIN nourishing and the production of body fluid promoting, relieving restlessness is quenched the thirst, effect of strong board stomach, invigorating middle warmer gas, intestine-stabling and anti-diarrheal.When boiling congee with Semen oryzae sativae, float over for dense fluids (being commonly called as rice water, medicated porridge oil) on pot face, have effect of tonify deficiency, the people weak for puerperal after being ill has auxiliary curative effect.The brown rice of Semen oryzae sativae is more nutritious than highed milled rice, and it can reduce cholesterol, reduces the probability of heart attack and apoplexy.The people of all body void suitable, the people of high heat, prolonged illness are just healed, women puerperal, old people, the young eupepsy of baby subtract weak person and be cooked into gruel and take good care of edible.
Powder of Radix Puerariae: powder of Radix Puerariae, also claims Pachyrhizua angulatus, and be the medical herbs that " China's book on Chinese herbal medicine " records, medicinal source is the tuber for legume pueraria lobata, Radix Puerariae rattan.Radix Puerariae includes the flavone compound of 12%, as nutritional labelings such as puerarin, daidzein glycosides, Semen arachidis hypogaeae elements, also have the mineral such as ferrum, calcium, copper, selenium of protein, aminoacid, sugar and needed by human, be all-ages famous and precious tonic, have the good reputation of " Radix Ginseng in thousand ".Existing medical value, effect of nutritious health care again.
Powder of Radix Puerariae, mainly contain relieve the effect of alcohol, blood fat reducing, blood pressure lowering, pathogenic fire reducing, heat-clearing and toxic substances removing, yang invigorating expelling pathogenic factors from muscles, spasmolysis and analgesia, rash antidiarrheal, increase brain and crown blood glucose, improve the effects such as brain microcirculation, be the important source material of the medicine preventing and treating the various diseases such as hypertension, hyperlipidemia, coronary heart diseases and angina pectoris, diabetes, cerebral thrombosis, gastroenteropathy, to women's cosmetology and health etc., there is special efficacy simultaneously.
Radix Salviae Miltiorrhizae: this product is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae.Bitter in the mouth, cold nature; GUIXIN, Liver Channel; Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.
Semen Persicae: this product is the dry mature seed of rosaceous plant Fructus Persicae or Prunus davidiana.Bitter in the mouth, sweet, property is put down; GUIXIN, liver, large intestine channel; Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.
Radix Angelicae Sinensis: this product is the dry root of umbelliferae angelica.Sweet in the mouth, pungent, warm in nature; Return liver, the heart, spleen channel; Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Olibanum: Burseraceae Boswellia carterii platymiscium Boswellia carterii, medicine glue XIANGSHU and wild Boswellia carterii etc., is used as medicine with the oleo-gum-resin that its trunk skin zone wound oozes out.Acrid in the mouth is bitter, warm in nature; Enter the heart, liver, spleen channel; Regulating qi and activating blood, analgesic therapy, chases after poison.
Flos Carthami: call red indigo plant flower, thorn Flos Carthami, Compositae, Flos Carthami platymiscium.Acrid in the mouth, warm in nature; Enter the heart, Liver Channel; Promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.
Myrrha: the oleo-gum-resin that Burseraceae bdellium plant myrrh and the trunk skin zone belonging to his kind of plant together ooze out.Bitter in the mouth, property is put down; Enter Liver Channel; Eliminating stasis to stop pain, externally used detumescence granulation promoting.
Radix Scrophulariae: this product is the dry root of goatweed Radix Scrophulariae.Sweet in the mouth, hardship, salty, cold nature; Return lung, stomach, kidney channel; Removing heat from blood YIN nourishing, eliminating fire and detoxication.
The Radix Astragali: this product is the dry root of leguminous plant Radix Astagali or Radix Astragali.Sweet in the mouth, warm in nature; Return lung, spleen channel; Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
Semen Ziziphi Spinosae: this product is the dry mature seed of Rhamnaceae plant Ziziphi Spinosae.Sweet in the mouth, acid, property is put down; Return liver, gallbladder, heart channel; Tonifying liver, mind calming, arresting sweating, promotes the production of body fluid.
Radix Notoginseng: this product is the dry root of panax araliaceae plant.Sweet in the mouth, micro-hardship, warm in nature; Return liver, stomach warp; Dissipating blood stasis stops blooding, subduing swelling and relieving pain.
The formulation analysis of health food of the present invention:
Chinese medicine thinks that coronary heart disease is the Primary Asthenia-Secondary Sthenia Syndrome of simulataneous insufficiency and excessive.Clinical manifestation has very big difference, depending on change of illness state when opinion is controlled with individual difference; Symptomatic treatment in acute condition, radical treatment in chronic case, or treating both the principal and the secondary aspects of a disease at the same time, make the sun in ambition unfold, and blood vessels run unimpeded.Effect a permanent cure and adopt the method for warming YANG and invigorating QI, nourishing YIN and benefiting blood; Take stopgap measures, with cold relieving, eliminating phlegm, the method such as to invigorate blood circulation.In a word, deficiency and excess be debated, bright specimen carries out tonify deficiency or removing the relative excess, or giving consideration to both the incidental and fundamental, carry out medicine typing treatment, just can obtain good effect.
This disease mostly is insufficiency of vital energy and blood, and negative and positive virtual loss, blood stasis due to qi deficiency, phlegm stagnation in collateral etc. cause.The common deficiency of clinical manifestation and deficient disease.Therefore, with benefiting vital QI and blood multiplex during treatment by Chinese herbs, nourishing YIN and invigorating YANG and so on rule is treated.Under " strengthening vital QI to eliminate pathogenic factors " principle instructs, first excise the factor of bringing out, increasing the weight of, the sufferer of radical cure itself.Eliminating evil with blood circulation promoting and blood stasis dispelling, warming and activating heart-YANG, eliminating phlegm dredging collateral, the chest stuffiness relieving of regulating the flow of vital energy, removing dampness dredging collateral, it is main for removing expectorant heat.
Radix Salviae Miltiorrhizae in formula of the present invention, Semen Persicae have effect of blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia; Radix Angelicae Sinensis, the Radix Astragali, Radix Scrophulariae have effect of benefiting vital QI and blood, YIN nourishing diuresis; Flos Carthami, Myrrha, Radix Notoginseng have effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; Olibanum, Semen Ziziphi Spinosae have effect of regulating qi and activating blood, tonifying liver mind calming; In addition, powder of Radix Puerariae and Semen oryzae sativae are except the nutrient substance such as rich in proteins, aminoacid, trace element, and also have the effects such as heat-clearing and toxic substances removing, yang invigorating expelling pathogenic factors from muscles, spasmolysis and analgesia, rash antidiarrheal, these are all of great advantage to patients with coronary heart disease.Can infer that health food of the present invention has good health-care effect to patients with coronary heart disease from raw material effect of formula.This health-care effect will be proved further in follow-up test.
Compared with prior art, the technical advantage of health food of the present invention is, it combines the function of food and medicine, for the daily health caring of patients with coronary heart disease with treatment is auxiliary provides suitable health product, makes patient's long-term taking; Its good health care effect, applied range, manufacturing process be simple and easy to do, be easy to apply.
Detailed description of the invention
Embodiment 1
Canned medicated porridge is produced with the optimal processing parameter of the arbitrary value in raw material range of the present invention and preparation method:
(1) raw material of Chinese medicine extract is accurately taken by illustrated formula: Radix Salviae Miltiorrhizae 3.2kg, Semen Persicae 1.0kg, Radix Angelicae Sinensis 2.0kg, Olibanum 0.3kg, Flos Carthami 1.2kg, Myrrha 0.5kg, Radix Scrophulariae 1.9kg, Radix Astragali 0.7kg, Semen Ziziphi Spinosae 2.0kg, Radix Notoginseng 0.6kg;
(2) all Chinese crude drugs are added the purified water of initial medical material 12 times of weight, soak 16 hours, backflow decoction 3 hours, filter, add the purified water of initial weight 9 times of weight again, backflow decoction 2 hours, filters and retains filtering residue, merging filtrate, being concentrated into 60 DEG C of relative densities is that the concentrated solution of 1.15-1.18 is for subsequent use;
(3) filtering residue of step (2) is added the ethanol of the concentration 75% of 8 times of weight, reflux, extract, 2 times, each 3 hours, filter, merging filtrate, distilling under reduced pressure removing ethanol, and to be concentrated into 60 DEG C of relative densities be that the concentrated solution of 1.15-1.18 is for subsequent use;
(4) merged by the concentrated solution of step (2) and (3) gained, continuing to be concentrated into 60 DEG C of relative densities is the concentrated liquid of tradition Chinese medicine of 1.23-1.27, is Chinese medicine extract, for subsequent use;
(5) Semen oryzae sativae 20kg, powder of Radix Puerariae 50kg is accurately taken by illustrated formula.Semen oryzae sativae is added the water of 7 times, boil 30 minutes; Water powder of Radix Puerariae being added 3 times is modulated into pasty state, adds in Semen oryzae sativae medicated porridge; Taking Chinese medicine extract 4kg by formula proportion adds in Semen oryzae sativae medicated porridge; Stir, continue to boil 10 minutes, be the raw material medicated porridge of nutrient porridge;
(6) in the raw material medicated porridge of step (5), add sucrose, make the health-care nutritive porridge of sweet taste, then utilize modern general Food Packaging technology to make canned medicated porridge, 350ml/ tank, it is 4.21g crude drug/tank that Chinese medicine ingredients content amounts to crude drug.
Embodiment 2
Canned medicated porridge is produced with the value of raw material optimum ratio of the present invention and the optimal processing parameter of preparation method:
(1) raw material of Chinese medicine extract is accurately taken by illustrated formula: Radix Salviae Miltiorrhizae 2.0kg, Semen Persicae 2.5kg, Radix Angelicae Sinensis 1.4kg, Olibanum 0.6kg, Flos Carthami 0.8kg, Myrrha 1.1kg, Radix Scrophulariae 1.2kg, Radix Astragali 1.5kg, Semen Ziziphi Spinosae 1.3kg, Radix Notoginseng 1.2kg;
(2) all Chinese crude drugs are added the purified water of initial medical material 12 times of weight, soak 16 hours, backflow decoction 3 hours, filter, add the purified water of initial weight 9 times of weight again, backflow decoction 2 hours, filters and retains filtering residue, merging filtrate, being concentrated into 60 DEG C of relative densities is that the concentrated solution of 1.15-1.18 is for subsequent use;
(3) filtering residue of step (2) is added the ethanol of the concentration 75% of 8 times of weight, reflux, extract, 2 times, each 3 hours, filter, merging filtrate, distilling under reduced pressure removing ethanol, and to be concentrated into 60 DEG C of relative densities be that the concentrated solution of 1.15-1.18 is for subsequent use;
(4) merged by the concentrated solution of step (2) and (3) gained, continuing to be concentrated into 60 DEG C of relative densities is the concentrated liquid of tradition Chinese medicine of 1.23-1.27, is Chinese medicine extract, for subsequent use;
(5) Semen oryzae sativae 50kg, powder of Radix Puerariae 25kg is accurately taken by illustrated formula.Semen oryzae sativae is added the water of 7 times, boil 30 minutes; Water powder of Radix Puerariae being added 3 times is modulated into pasty state, adds in Semen oryzae sativae medicated porridge; Taking Chinese medicine extract 8kg by formula proportion adds in Semen oryzae sativae medicated porridge; Stir, continue to boil 10 minutes, be the raw material medicated porridge of nutrient porridge;
(6) in the raw material medicated porridge of step (5), add sucrose, make the health-care nutritive porridge of sweet taste, then utilize modern general Food Packaging technology to make canned medicated porridge, 350ml/ tank, it is 4.21g crude drug/tank that Chinese medicine ingredients content amounts to crude drug.
Embodiment 3
Produce not containing the canned medicated porridge of Chinese medicine extract with the optimal processing parameter of the value of raw material optimum ratio of the present invention and preparation method:
(1) Semen oryzae sativae 50kg, powder of Radix Puerariae 25kg is accurately taken by illustrated formula;
(2) Semen oryzae sativae is added the water of 7 times of weight, boil 30 minutes.Water powder of Radix Puerariae being added 3 times of weight is modulated into pasty state, adds in Semen oryzae sativae medicated porridge, continues to boil 10 minutes, is the raw material medicated porridge of the nutrient porridge not adding Chinese medicine ingredients;
(3) in the raw material medicated porridge of step (2), add sucrose, make the health-care nutritive porridge of sweet taste, then utilize modern general Food Packaging technology to make canned medicated porridge, 350ml/ tank.
Embodiment 4
Produce only containing Chinese medicine ingredients (after removing Semen oryzae sativae and powder of Radix Puerariae) canned medicated porridge with the optimal processing parameter of the value of raw material optimum ratio of the present invention and preparation method:
(1) raw material of Chinese medicine extract is accurately taken by illustrated formula: Radix Salviae Miltiorrhizae 2.0kg, Semen Persicae 2.5kg, Radix Angelicae Sinensis 1.4kg, Olibanum 0.6kg, Flos Carthami 0.8kg, Myrrha 1.1kg, Radix Scrophulariae 1.2kg, Radix Astragali 1.5kg, Semen Ziziphi Spinosae 1.3kg, Radix Notoginseng 1.2kg;
(2) all Chinese crude drugs are added the purified water of initial medical material 12 times of weight, soak 16 hours, backflow decoction 3 hours, filter, add the purified water of initial weight 9 times of weight again, backflow decoction 2 hours, filters and retains filtering residue, merging filtrate, being concentrated into 60 DEG C of relative densities is that the concentrated solution of 1.15-1.18 is for subsequent use;
(3) filtering residue of step (2) is added the ethanol of the concentration 75% of 8 times of weight, reflux, extract, 2 times, each 3 hours, filter, merging filtrate, distilling under reduced pressure removing ethanol, and to be concentrated into 60 DEG C of relative densities be that the concentrated solution of 1.15-1.18 is for subsequent use;
(4) merged by the concentrated solution of step (2) and (3) gained, continuing to be concentrated into 60 DEG C of relative densities is the concentrated liquid of tradition Chinese medicine of 1.23-1.27, is Chinese medicine extract, for subsequent use;
(5) be brewed into pasty state by common starch, take Chinese medicine extract 8kg by formula proportion and add in paste; Stir, continue to boil 10 minutes, be the raw material medicated porridge of nutrient porridge;
(6) in the raw material medicated porridge of step (5), add sucrose, make the health-care nutritive porridge of sweet taste, then utilize modern general Food Packaging technology to make canned medicated porridge, 350ml/ tank, it is 4.21g crude drug/tank that Chinese medicine ingredients content amounts to crude drug.
Test example 1: the toxicity test of health food of the present invention
(1) acute toxicity test
Acute toxicity test is carried out: get 20 mices, this medicated porridge of oral administration gavage maximum (saturation capacity of maximum administration volume) 150g/kg, Continuous Observation 7 days, itemized record reaction of animals situation with health care congee prepared by embodiment 1 and embodiment 2.Result shows: after 20 Mouse oral (gavage) maximums, activity is all without exception, and body weight increases, and none is dead.And its amount far exceedes the amount of people, be 5 times of people's amount (tank every day 6), show that it is without acute toxicity, edible safety is very high.
(2) long term toxicity test:
Adopt health care congee that Wistar rat produces with embodiment 1 and embodiment 2 for Major Foods, continuous oral (gavage) administration 20 weeks its long term toxicities of observation, and establish the feedstuff of blank group gavage equivalent amount.Experimental animal outward appearance behavioral activity is normal; Body weight is respectively organized all in rising trend; Pathological examination, each treated animal internal organs all do not find that substantial cellular damages; Hematological indices, hemoglobin (Hb) and numeration of leukocyte value, blood parameters paddy third Cyklokapren (SGDT, reitman-frankel method) and urea nitrogen (urease methods) etc., each sample group and blank group no significant difference (P > 0.05).Illustrate that health food of the present invention is fool proof.
Test example 2: the clinical trial of health food of the present invention
1, physical data
The People's Hospital of this clinical trial Shi Yumou city cooperates, and from this Out-patient Department and the patients with coronary heart disease of being in hospital, filters out 360 routine patients and take part in this test voluntarily, subject age 26-67 year, 58.4 years old mean age, man 200 example, female 160 example.All experimenters are commented and is divided into contrast 1, contrast 2, contrast 3, test 1 and test 2 groups, totally 5 groups, often organize 72 people, male 40 people, female 32 people, makes these 5 groups have comparability on statistical significance at age, sex, the course of disease, Therapeutic Method (except this experiment) when dividing into groups.
2, test sample
Control sample A: for testing special gelatinized corn starch, specification 350ml/ tank;
Control sample B: the canned medicated porridge not containing Chinese medicine extract that the embodiment of the present invention 3 is produced, specification 350ml/ tank;
Control sample C: what the embodiment of the present invention 4 was produced only contains Chinese medicine ingredients (after removing Semen oryzae sativae and powder of Radix Puerariae) canned medicated porridge, specification 350ml/ tank, and it is 4.21g crude drug/tank that Chinese medicine ingredients content amounts to crude drug;
Test specimen 1: the canned medicated porridge that the embodiment of the present invention 1 is produced, specification 350ml/ tank, it is 4.21g crude drug/tank that Chinese medicine ingredients content amounts to crude drug.
Test specimen 2: the canned medicated porridge that the embodiment of the present invention 2 is produced, specification 350ml/ tank, it is 4.21g crude drug/tank that Chinese medicine ingredients content amounts to crude drug.
3, test method
This clinical trial is participated under the prerequisite that all experimenters all normally carry out in the treatment plan that hospital is original, contrast 1 group and eat control sample A, contrast 2 groups and eat control sample B, contrast 3 groups and eat control sample C, test 1 group and eat test specimen 1, test 2 groups and eat test specimen 2, the consumption of each group is every day 3 times, each 1 tank, uses with canteen.Continuous use two months, carry out record to patient in the sign performance of treatments period, statistics therapeutic outcome is analyzed.
4, health-care effect evaluation
The health-care effect of this experiment is evaluated according to the adjuvant treatment effect of this health food, because for the patient failed to respond to any medical treatment, hospital can take additive method to treat, and therefore there is not invalid situation during this Experimental Evaluation.
5, therapeutic outcome
(1) compare experimenter to find, test 1 group, test the health such as complexion, the mental status of 2 groups significantly better than other group.Test 1 group and test 2 groups of patients energeticallyer, appetite is better, the colour of skin is better, the empty symptom of breathing hard of body disappears substantially, and it is less better to contrast 3 groups of situations, contrasts 2 groups to take second place, contrast 1 group the poorest.
(2), after the test plan of all experimenters completes, statistical analysis is carried out to therapeutic outcome, as shown in table 1.
Table 1 result of the test statistical analysis table
Table 1 result shows, compared with blank 1 group, contrast 2, contrast 3, test 1 and test 2 groups of cure rates and obvious effective rate have raising in various degree, test 1, test the particularly evident of 2 groups of raisings, it is than contrast 1 group, cure rate all improves 11.1%, obvious effective rate improves 19.5% and 20.9% respectively, and the effect that this assosting effect combines than contrast 2 and contrast 3 is also good, illustrate that Chinese medicine extract and basal nutrient material there occurs synergism, there occurs 1 and add the effect that 1 is far longer than 2.
6, conclusion
Known by clinical trial, the treatment of health care congee of the present invention to coronary heart disease serves assosting effect well, on the basis of the nutritional condition and Chinese medicine conditioning that improve patient, promote conventional treatment better, therefore, the health care of health care congee of the present invention and adjuvant treatment effect are very remarkable, and the present invention achieves breakthrough technical progress and technological achievement in this field.
Claims (2)
1. prepare a method for the health-care nutritive porridge eaten for patients with coronary heart disease, it is characterized in that concrete steps are as follows:
(1) the various raw material of following weight portion is taken: Semen oryzae sativae 20-80 part, powder of Radix Puerariae 10-50 part, Chinese medicine extract 4-18 part; The wherein composition of Chinese medicine extract: Radix Salviae Miltiorrhizae 8-32 part, Semen Persicae 10-40 part, Radix Angelicae Sinensis 8-20 part, Olibanum 3-9 part, Flos Carthami 4-12 part, Myrrha 5-17 part, Radix Scrophulariae 6-19 part, Radix Astragali 7-24 part, Semen Ziziphi Spinosae 7-20 part, Radix Notoginseng 6-18 part;
(2) all Chinese crude drugs comprised by Chinese medicine extract add the purified water of initial medical material 5-15 times weight, soak 6-24 hour, backflow decocts 1-6 hour, filter, add the purified water of initial weight 4-12 times weight again, backflow decocts 1-5 hour, filters and retains filtering residue, merging filtrate, being concentrated into 60 DEG C of relative densities is that the concentrated solution of 1.15-1.18 is for subsequent use;
(3) filtering residue of step (2) is added the ethanol of the concentration 60-85% of 5-12 times of weight, reflux, extract, 2 times, each 1-6 hour, filter, merging filtrate, distilling under reduced pressure removing ethanol, and to be concentrated into 60 DEG C of relative densities be that the concentrated solution of 1.15-1.18 is for subsequent use;
(4) merged by the concentrated solution of step (2) and (3) gained, continuing to be concentrated into 60 DEG C of relative densities is the concentrated liquid of tradition Chinese medicine of 1.23-1.27, is Chinese medicine extract, for subsequent use;
(5) Semen oryzae sativae is added the water of 5-9 times of weight, boil 15-60 minute, water powder of Radix Puerariae being added 2-5 times of weight is modulated into pasty state, adds in Semen oryzae sativae medicated porridge; Taking Chinese medicine extract by formula proportion adds in Semen oryzae sativae medicated porridge; Stir, continue to boil 5-20 minute, be the raw material medicated porridge of nutrient porridge;
(6) in the raw material medicated porridge of step (5), the adjuvant such as sucrose, Sal is added, the health-care nutritive porridge of various taste can be made, also can make the powdery medicated porridge that can brew by technology such as vacuum dryings, then utilize modern general Food Packaging technology to make and be variously convenient for carrying edible packaged form.
2. the method preparing the health-care nutritive porridge eaten for patients with coronary heart disease according to claim 1, is characterized in that: the packaged form of described health-care nutritive porridge is a bowl medicated porridge, pop can or packed medicated porridge.
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