CN105395670A - Liquid medicine for treating dermatophytosis - Google Patents

Liquid medicine for treating dermatophytosis Download PDF

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Publication number
CN105395670A
CN105395670A CN201511010473.0A CN201511010473A CN105395670A CN 105395670 A CN105395670 A CN 105395670A CN 201511010473 A CN201511010473 A CN 201511010473A CN 105395670 A CN105395670 A CN 105395670A
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Prior art keywords
parts
weight
phenol
beriberi
liquid medicine
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CN201511010473.0A
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Chinese (zh)
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不公告发明人
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Tianjin Jun Ru Science And Technology Ltd
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Tianjin Jun Ru Science And Technology Ltd
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Priority to CN201511010473.0A priority Critical patent/CN105395670A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234—Cnidium (snowparsley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/758—Zanthoxylum, e.g. pricklyash
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to liquid medicine for treating dermatophytosis. The liquid medicine is prepared from, by weight, 6-9 parts of golden cypress, 6-9 parts of rheum officinale, 6-9 parts of fructus kochiae, 6-9 parts of fructus cnidii, 6-9 parts of golden larch bark, 3-6 parts of camphor, 6-9 parts of pepper, 500 parts of 12-13-degree white vinegar and 6-9 parts of phenol with the concentration ranging from 1.3%-2%; according to the optimal matching, the medicament is prepared from, by weight, 5 parts of the golden cypress, 5 parts of the rheum officinale, 5 parts of the fructus kochiae, 5 parts of the fructus cnidii, 5 parts of the golden larch bark, 3 parts of the camphor, 5 parts of the pepper, 500 parts of the white vinegar and 5 parts of the phenol; the preparation method includes the steps that the golden cypress, the rheum officinale, the fructus kochiae, the fructus cnidii, the golden larch bark, the camphor and the pepper are weighed by weight and placed into the white vinegar for being soaked for six days, a socked material is taken out, the remaining leaching liquid is filtered for standby use, the phenol is weighed by weight, added to the filtrated for standby use and heated, heating is stopped when the temperature reaches 65 DEG C, after the temperature is lowered to the room temperature, packaging is conducted, a finished product of the liquid medicine for treating dermatophytosis is obtained, and the liquid medicine is applied to the wounded part when being used.

Description

A kind of liquid medicine for the treatment of beriberi
Technical field
The present invention relates to a kind of medicine for the treatment of beriberi, especially a kind of liquid medicine for the treatment of beriberi.
Background technology
Beriberi is a kind of common length in the dermatosis caused because of superficial part fungal infection of foot, Chinese medicine is called tinea pedis, some pars affecta skins are coarse, thickening, decortication, winter easily chap: have get existing vesicle, erosion, skin wet at toe, turn white, fray Lao Pi after see flushing, ooze out yellow fluid, unbearably scratchy, recurrent exerbation, spring and summer increases the weight of, and the autumn and winter alleviate.The harm of beriberi can not be ignored, and both affects daily life during morbidity, affects personal image again, and may cause secondary infection, infects other positions of health, brings very large misery and worry to patient.At present, the Pharmaceuticals of market being treated beriberi is a lot, and curative effect is very different, the problems such as cure rate is low, recurrence rate is high, side effect is large and treatment cycle is long that have a lot of medicine to exist, and a lot of patient is not broken away from worry that vitamin B1 deficiency brings is with painful.
Summary of the invention
The object of the invention is the deficiency existed to overcome above-mentioned prior art, a kind of liquid medicine for the treatment of beriberi being provided, it is not only treated, and beriberi is effective, instant effect, esy to use, safe and reliable, and not easily to recur.
The technical solution adopted in the present invention is achieved in that it is by the preparation of raw material of following weight parts meter: Cortex Phellodendri 6 ~ 9 parts, Radix Et Rhizoma Rhei 6 ~ 9 parts, the Fructus Kochiae 6 ~ 9 parts, Fructus Cnidii 6 ~ 9 parts, Cortex Pseudolaricis 6 ~ 9 parts, Camphora 3 ~ 6 parts, 6 ~ 9 parts, Pericarpium Zanthoxyli, white vinegar 500 parts and phenol 6 ~ 9 parts; Optimum weight part meter proportioning of above-mentioned medicament is: Cortex Phellodendri 5 parts, Radix Et Rhizoma Rhei 5 parts, the Fructus Kochiae 5 parts, Fructus Cnidii 5 parts, Cortex Pseudolaricis 5 parts, Camphora 3 parts, 5 parts, Pericarpium Zanthoxyli, white vinegar 500 parts and phenol 5 parts; Its preparation method takes Cortex Phellodendri by above-mentioned parts by weight, Radix Et Rhizoma Rhei, the Fructus Kochiae, Fructus Cnidii, Cortex Pseudolaricis, Camphora, Pericarpium Zanthoxyli are put together, put into after removing impurity in white vinegar by weight and soak, when soaking 3 days, stir up and down once, soak 3 days again, take out soak, the leachate of remainder is filtered, stand-by, take phenol by weight, add in stand-by filtrate, heating, during to 65 DEG C, stop heating, stir 5 minutes, stop stirring, drop to until temperature and to carry out subpackage after room temperature and namely obtain treatment beriberi medicine liquid finished product, the used time smears affected part.
In the technical solution used in the present invention, described white vinegar is 12 ~ 13 degree of food stage white vinegars.
In the technical solution used in the present invention, described phenol, its concentration is 1.3% ~ 2%, and described phenol is also called carbolic acid.
The traditional Chinese medical science is thought: vitamin B1 deficiency mostly is warm invasion and attack, and damp invasion of lower energizer is done; Modern medicine thinks that mainly fungal infection causes, in conjunction with Chinese and western medicine theory, control when with heat clearing away by wet, detoxicating, killing bacteria.The present invention, from the cause of disease, the pathology of beriberi, selecting Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication, bringing down a fever except steaming; Radix Et Rhizoma Rhei purges heat poison, clearing away heat and cooling blood, removing toxic substances removing blood stasis; Fructus Kochiae clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching; Fructus Cnidii warming the kidney to invigorate YANG, dampness is dispeled the wind, parasite killing; Cortex Pseudolaricis parasite killing, treat tinea, antipruritic; Camphora: sensible, parasite killing; Pericarpium Zanthoxyli: warming middle-JIAO to relieve pain, killing parasites for relieving itching; White vinegar antifungal, control beriberi, allaying tiredness, regulate unclog and readjust, Yin Yang balancing, enhancing blood circulation; Stupid phenol antifungal, antipruritic, there is penetrance, easily absorb from skin.All medicines share, removing dampness is dispeled the wind, sterilizing and itch-relieving, horny layer softening, protection epidermis, pathogenic tinea bacterium must be gone out, and beriberi must heal.
The present invention also can be used for the skin diseases such as treatment skin pruritus, urticaria, eczema, herpes zoster, scabies.
Compared with prior art, compatibility rationally, does not contain injurious factor, has no side effect in the present invention; Processing technology is simple, and drug effect is powerful, and curative effect is obvious, and not easily recur, with low cost, using patient of the present invention, within 1 ~ 2 week, can fully recover, is treat one of ideal medicine of beriberi at present.
Detailed description of the invention
Embodiment 1: the present invention is by the preparation of raw material of following weight parts meter: Cortex Phellodendri 6 ~ 9 parts, Radix Et Rhizoma Rhei 6 ~ 9 parts, the Fructus Kochiae 6 ~ 9 parts, Fructus Cnidii 6 ~ 9 parts, Cortex Pseudolaricis 6 ~ 9 parts, Camphora 3 ~ 6 parts, 6 ~ 9 parts, Pericarpium Zanthoxyli, 12 ~ 13 degree of white vinegars 500 parts and 1.3 ~ 2% phenol 6 ~ 9 parts; Its preparation method takes Cortex Phellodendri by above-mentioned parts by weight, Radix Et Rhizoma Rhei, the Fructus Kochiae, Fructus Cnidii, Cortex Pseudolaricis, Camphora, Pericarpium Zanthoxyli are put together, put into after removing impurity in white vinegar by weight and soak, when soaking 3 days, stir up and down once, continue immersion after 3 days, take out soak, the leachate of remainder is filtered, stand-by, take phenol by weight, add in stand-by filtrate and heat, during to 65 DEG C, stop heating, stir 5 minutes, drop to until temperature and to carry out subpackage after room temperature and namely obtain treatment beriberi medicine liquid finished product, the used time smears affected part.
Embodiment 2: optimum weight part of the present invention meter proportioning is: Cortex Phellodendri 5 parts, Radix Et Rhizoma Rhei 5 parts, the Fructus Kochiae 5 parts, Fructus Cnidii 5 parts, Cortex Pseudolaricis 5 parts, Camphora 3 parts, 5 parts, Pericarpium Zanthoxyli, 12 ~ 13 degree of white vinegars 500 parts and 1.3 ~ 2% phenol 5 parts; Its preparation method is identical with embodiment 1.
Case 1: practise ××, man 42, geological significance in Hongqiling mine nickel industry office laborers, suffer from beriberi 8 years, vitamin B1 deficiency recurrent exerbation, can not work time serious.Successively to hospital of Nie Ye company, hospital of Jilin Province, Jilin Prov. Traditional Chiense Medical College's treatment, symptom alleviates to some extent, recurrent exerbation after drug withdrawal, and toe is rotten to the corn.After being introduced, in March, 2009, I sought medical advice, and I uses the beriberi medicine liquid of the embodiment of the present invention 2, advises it to smear, and one week effective, recovery from illness in two weeks.Follow up a case by regular visits to, so far no recurrence.
Case 2: high ××, man, 33 years old, huge rock people from Hulan, suffered from beriberi 5 years, foot's stench, the full room of foul smell, kith and kin for this reason away from.Successively use more than 20 kind of beriberi medicine to treat beriberi for eliminating stench patient, therapeutic effect is poor, treating beriberi DeGrain, and foot is foul smelling still, and patient suffers untold misery for this reason.In May, 2011, come me upon somebody's introduction and sought medical advice, what I used the embodiment of the present invention 1 controls beriberi medicine liquid, advises and adheres to its every day using, and after one week, foot's stink disappears, and beriberi takes a favorable turn, and continues medication, and less than three weeks, foot recovered normal, beriberi healing.
Case 3: Lee's ××, female, 38 years old, people from Huinan County.Suffer from beriberi 5 years, foot's pruritus is hard to bear on ordinary days, the medicine of the treatment such as the beriberi liquor beriberi that life-time service pharmacy sells, and result therapeutic effect is poor, does not prolongedly heal, and patient suffers untold misery.In June, 2012, I cured, and I uses the beriberi medicine liquid of controlling of the embodiment of the present invention 1 to cure, and advises again and adheres to its every day of going home using, and use rear same day foot's pruritus to alleviate, within one week, rear feet is without pruritus, and after using three weeks, beriberi is cured, and patient recovers normal.

Claims (4)

1. treat a liquid medicine for beriberi, it is characterized in that it is by the preparation of raw material of following weight parts meter: Cortex Phellodendri 6 ~ 9 parts, Radix Et Rhizoma Rhei 6 ~ 9 parts, the Fructus Kochiae 6 ~ 9 parts, Fructus Cnidii 6 ~ 9 parts, Cortex Pseudolaricis 6 ~ 9 parts, Camphora 3 ~ 6 parts, 6 ~ 9 parts, Pericarpium Zanthoxyli, white vinegar 500 parts and phenol 6 ~ 9 parts; Its preparation method takes Cortex Phellodendri by above-mentioned parts by weight, Radix Et Rhizoma Rhei, the Fructus Kochiae, Fructus Cnidii, Cortex Pseudolaricis, Camphora, Pericarpium Zanthoxyli are put together, put into after removing impurity in white vinegar by weight and soak, when soaking 3 days, stir up and down once, after soaking 3 days again, take out soak, the leachate of remainder is filtered, stand-by, take phenol by weight, add in stand-by filtrate, heating, during to 65 DEG C, stop heating, stir 5 minutes, stop stirring, drop to until temperature and to carry out subpackage after room temperature and namely obtain treatment beriberi medicine liquid finished product, the used time smears affected part.
2. a kind of liquid medicine for the treatment of beriberi according to claim 1, is characterized in that: optimum weight part meter proportioning of above-mentioned medicament is: Cortex Phellodendri 5 parts, Radix Et Rhizoma Rhei 5 parts, the Fructus Kochiae 5 parts, Fructus Cnidii 5 parts, Cortex Pseudolaricis 5 parts, Camphora 3 parts, 5 parts, Pericarpium Zanthoxyli, white vinegar 500 parts and phenol 5 parts; Its preparation method takes Cortex Phellodendri by above-mentioned parts by weight, Radix Et Rhizoma Rhei, the Fructus Kochiae, Fructus Cnidii, Cortex Pseudolaricis, Camphora, Pericarpium Zanthoxyli are put together, put into after removing impurity in white vinegar by weight and soak, when soaking 3 days, stir up and down once, after soaking 3 days again, take out soak, the leachate of remainder is filtered, stand-by, take phenol by weight, add in stand-by filtrate, heating, during to 65 DEG C, stop heating, stir 5 minutes, stop stirring, drop to until temperature and to carry out subpackage after room temperature and namely obtain treatment beriberi medicine liquid finished product, the used time smears affected part.
3. a kind of liquid medicine for the treatment of beriberi according to claim 1, is characterized in that: described white vinegar is 12 ~ 13 degree of food stage white vinegars.
4. a kind of liquid medicine for the treatment of beriberi according to claim 1, is characterized in that: described phenol concentration is 1.3% ~ 2%, and described phenol is also called carbolic acid.
CN201511010473.0A 2015-12-28 2015-12-28 Liquid medicine for treating dermatophytosis Pending CN105395670A (en)

Priority Applications (1)

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CN201511010473.0A CN105395670A (en) 2015-12-28 2015-12-28 Liquid medicine for treating dermatophytosis

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Application Number Priority Date Filing Date Title
CN201511010473.0A CN105395670A (en) 2015-12-28 2015-12-28 Liquid medicine for treating dermatophytosis

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CN105395670A true CN105395670A (en) 2016-03-16

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106236922A (en) * 2016-08-30 2016-12-21 重庆主流生物工程有限公司 A kind of Chinese medicine composition treating tinea pedis or tinea pedis and preparation method thereof
CN111012852A (en) * 2020-01-09 2020-04-17 邓传孝 Liquid medicine formula for treating beriberi and using method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106236922A (en) * 2016-08-30 2016-12-21 重庆主流生物工程有限公司 A kind of Chinese medicine composition treating tinea pedis or tinea pedis and preparation method thereof
CN111012852A (en) * 2020-01-09 2020-04-17 邓传孝 Liquid medicine formula for treating beriberi and using method thereof

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Application publication date: 20160316