CN105393933A - Non-human primate animal reaction behavior testing system - Google Patents

Non-human primate animal reaction behavior testing system Download PDF

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Publication number
CN105393933A
CN105393933A CN201510940593.4A CN201510940593A CN105393933A CN 105393933 A CN105393933 A CN 105393933A CN 201510940593 A CN201510940593 A CN 201510940593A CN 105393933 A CN105393933 A CN 105393933A
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animal
pedal
module
chair
protective clothing
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CN201510940593.4A
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CN105393933B (en
Inventor
王晓菲
程涛
王全军
董延生
关勇彪
王和枚
韩刚
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Institute of Pharmacology and Toxicology of AMMS
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Institute of Pharmacology and Toxicology of AMMS
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Priority to CN201510940593.4A priority Critical patent/CN105393933B/en
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K29/00Other apparatus for animal husbandry
    • A01K29/005Monitoring or measuring activity, e.g. detecting heat or mating
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/02Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/03Housing for domestic or laboratory animals
    • A01K1/031Cages for laboratory animals; Cages for measuring metabolism of animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes

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  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Clinical Laboratory Science (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Housing For Livestock And Birds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention relates to a non-human primate animal reaction behavior testing system comprising an animal self-drug delivery system operation box, a fixed chair and protection clothes. The fixed chair is placed in the operation box; the operation box is cooperatively equipped with testing equipment testing animal reaction behaviors; the fixed chair is formed by a chair seat and a chair back; the back part of the protection clothes is provided with a protection box accommodating a body surface retention tube; and the protection box can be fixed on the chair back to fix the protection clothes, so an animal can be fixed and animal behaviors can be tested via the testing equipment. Various demands during the testing process can be thoroughly met by the use of the testing system and the testing process can be simplified, so testing cost can be lowered; the animal can be fixed with the back of the animal fixation during the test, so arms and legs of the animal can freely move; and animal behaviors can be accurately monitored.

Description

Non-human primate reflex action pilot system
Technical field
The present invention relates to non-human primate behavior test research field, particularly relate to a kind of non-human primate reflex action pilot system.
Background technology
As the non-human primate of mankind close relative, monkey has higher IQ, is the ideal animals model of drugs reaction.The Behavior Test of monkey comprises the behavior of autonomous picked-up foodstuff, intravenous self administration behavior etc., and namely animal obtains food or intravenous addictive drug as award by conditioned reflex sexual behavior.And intravenous injection all needs pipeline to pass from skin surface, and be retained in skin surface, test to connect infusion pump or electric stimulating instrument etc., according to test situation, the pipeline of indwelling may need Preserving time in animals, and this process generally completes in independent control box.
Because monkey has the non-human primate compared with high iq; time clear-headed, four limbs are strong very flexibly; thus when testing monkey; fixture generally can be adopted to be fixed by monkey; and body surface indwelling pipeline is protected, to prevent it from indwelling pipeline pullled damage or stinging rotten, and according to test requirements document; animal needs to keep mobility that is clear-headed and four limbs, to complete the monitoring to reaction of animals behavior.The fixture of current employing is that monkey fixes chair mostly, and it has the function of protection body surface indwelling equipment, is a kind ofly not to be damaged and the device of chair-like monkey local body fixed for the postoperative protection of animal body embedded set passes skin body surface indwelling position.
Generally adopt in prior art and fixed by monkey in two ways, the first is that the four limbs of monkey, waist and neck is fixing on the seat respectively by fixed band, makes the limitation of activity of monkey to protect body surface indwelling tube line.But the neck of this kind of fixing chair on monkey may hinder it on the observation of surrounding environment and reaction after fixing thus affect test effect; and this kind of fixing chair is only applicable to the disposable experiment of short time; because the long-time health to monkey and four limbs constraint easily cause anxiety; and after monkey leaves fixing chair; with it without any pipeline protection measure; therefore repeatedly testing of long-term (as a couple of days, the even several months) is not suitable for.Another kind first puts on the protective clothing with slide fastener to monkey, and protective clothing is provided with the opening of drawing for pipeline, and then fix on the seat, but current protective clothing dress comparatively difficulty, and monkey chaeta is easily clamped in slide fastener design, stuck, is unfavorable for Reusability; And indwelling tube goes out young, easily damage body surface indwelling tube when protective clothing has and moves by a small margin.
And, above-mentioned monkey fix chair be placed on test in control box time, first to consider the cooperation of bulk, also need design independent fastener seat is fixed in control box.And existing control box generally relies on import, expensive, and part of module layout in control box is not too reasonable; In addition; the monkey of abroad doing experiment and domestic test use monkey build difference larger; be difficult to the demand adapting to test at present; thus need to study a set of pilot system being applicable to testing the reflex action of domestic non-human primate; to facilitate the various demands in test; such as: fixing animal, protection indwelling pipeline, to operation behavior when conditioned reflex of foodstuff, intravenous injection, animal and logging etc., to obtain result of the test more really and accurately.
Summary of the invention
The object of the invention is to propose a kind of non-human primate reflex action pilot system, the various operational requirements in non-human primate reflex action test can be met comprehensively and easily, and obtain result of the test more really and accurately.
For achieving the above object, the invention provides a kind of non-human primate reflex action pilot system, comprising: animal self administration Dynamic System case A, fixing chair B and protective clothing C,
Described fixing chair B is located in described control box A, and described control box A is supporting is provided with the test equipment tested the reflex action of animal A.5;
Described fixing chair B comprise seat support B.1 with the chair back B.2; C.2 the back of described protective clothing C is provided with the protection box of accommodation body surface indwelling tube; C.2, described protection box can be fixed on the described chair back and B.2 go up; for being C.2 fixed described protective clothing C by described protection box; and then realize fixing, A.5 to be tested the behavior of described animal by described test equipment described animal.
Further, A.1 described control box A also comprises control box main body and dividing plate, and A.5 described test equipment comprises signal stimulus module, reacting record modules A .7 and award module, wherein:
A.1, described dividing plate is positioned at described control box body interior, and the inner space of described control box main body is divided into proparea A.2 with back zone A.3, described proparea is A.2 for placing described fixing chair B;
A.3 described signal stimulus module is located at described back zone, for carrying out environmental stimuli to described animal;
Described reacting record modules A .7 is located at described back zone A.3 or outside described control box A, for carrying out record to the operation of described animal;
Described award module is located at described back zone A.3 or outside described control box A, gives corresponding award for the operating data recorded according to described reacting record modules A .7 to described animal.
Further, described control box A also comprises pedal module, described pedal module is located at described back zone A.3 or outside described control box A, described pedal module is connected with described reacting record modules A .7 signal, for receiving the operation of described animal to described pedal module, and record the operating data of described animal by described reacting record modules A .7.
Further, described pedal module comprise pedal box A.13 with pedal A.14, A.13, A.3 described pedal box is installed on described back zone, described pedal A.14 by elastic mechanism be installed on described pedal box A.13 in, described elastic mechanism can realize the reset A.14 of described pedal, A.13 described pedal A.14 part exposes described pedal box, and A.2 described pedal exposed portion is A.14 positioned at described proparea, presses to enable described animal.
Further, A.12 the top outer of described control box A is provided with mounting platform, described pedal module is arranged at described mounting platform and A.12 goes up, A.13 described pedal module comprises pedal box, pedal A.14, lever A.15, spring A.16 with chain A.17, described pedal A.14 by elastic mechanism be installed on described pedal box A.13 in, described elastic mechanism can realize the reset A.14 of described pedal, A.14, A.13 described pedal partly exposes described pedal box, described lever one end is A.15 rotatably connected to described mounting platform and A.12 goes up, the other end is overlapped on described pedal exposed portion A.14, A.16, described spring is arranged at described mounting platform A.12 and between described lever middle part A.15, described chain be A.17 connected to described spring A.16 with the junction at described lever middle part A.15, described chain A.17 through described spring A.16 and hang on described proparea A.2, pull to enable described animal.
Further, described award module comprises foodstuff delivery module and/or intravenous injection automatic chemical feeding modules A .6, wherein said foodstuff delivery module is used for delivering food or drug particles to described animal, described intravenous injection automatic chemical feeding modules A .6 is used for the intravenous liquid medicine to described animal, described foodstuff delivery module and/or described intravenous injection automatic chemical feeding modules A .6 are connected with described reacting record modules A .7 signal, carry out feeding or automatic chemical feeding with the operating data recorded according to described reacting record modules A .7 to described animal.
Further, the formula crib of leaning out is provided with A.10 in the side A.2, proparea of described control box A, to facilitate described animal to capture food, A.10 described foodstuff delivery module and the described formula crib that leans out cooperatively interact, with by lean out described in described food input formula crib A.10 in.
Further, described intravenous injection automatic chemical feeding modules A .6 comprises syringe pump and propulsive mechanism, according to the operating data that described reacting record modules A .7 records, described intravenous injection automatic chemical feeding modules A .6 can control described propulsive mechanism and apply to preset the amount of feeding to described syringe pump.
Further, described intravenous injection automatic chemical feeding modules A .6 also comprises pipeline, and one end of described pipeline is located in the skin surface of described animal, and the other end is connected with described syringe pump.
Further, A.2 the proparea of described control box A is also provided with indicator lamp or loudspeaker, and described indicator lamp or loudspeaker are electrically connected with described signal stimulus module, to carry out light or Sound stimulat to described animal.
Further, the proparea tank wall A.2 of described control box A be provided with air-vent, illuminating lamp A.8 with camera A.9.
Further, A.1 described control box main body and described dividing plate all adopt acoustic material.
Further, bottom A.2, described proparea or both sides are also provided with holding section, described holding section for installing described fixing chair B, and forms slide construction with the respective outer side edges of described fixing chair B relevant position, pulls out or push described proparea A.2 to enable described fixing chair B.
Further; described fixing chair B comprises: seat support B.1 with the chair back B.2; B.2, the described chair back is provided with cavernous structure; described cavernous structure is positioned at described seat support B.1 top; can be C.2 suitable with described protection box; for being C.2 fixed described protective clothing C by described protection box, and then realize fixing described animal.
Further, B.2 the described chair back offers described cavernous structure from top, also comprises pin B.25, after C.2 described protection box is pushed described cavernous structure from described chair back top B.2, carries out spacing to described protection box upper end C.2.
Further; B.2, the described chair back comprises: fixed head B.21 with sliding panel B.22; B.21, described fixed head is provided with gathering sill from top; B.22, described sliding panel to be embedded in described gathering sill and the Height Adjustment that can slide up and down to realize to described protection box C.2 fixed position along described gathering sill, and described cavernous structure is located at described sliding panel and B.22 goes up.
Further, B.22 described sliding panel offers described cavernous structure from top, also comprises pin B.25, after C.2 described protection box is pushed described cavernous structure from described fixed head top B.21, carries out spacing to described protection box upper end C.2.
Further, B.24 described fixing chair B also comprises guard bar, and B.24 described guard bar is overlapped on the upper end of described gathering sill.
Further, described fixing chair B also comprises secure component, and C.2 described secure component moves along the fore-and-aft direction of described fixing chair B for limiting described protection box.
Further, B.1 described seat support can slide up and down to be located at described chair back side B.2 to realize described seat support Height Adjustment B.1.
Further, B.4 described fixing chair B also comprises two the first bracing pieces, each described first bracing piece one end is B.4 connected with described seat support free end B.1, the other end can slide up and down to be connected to the described chair back and B.2 go up, and described seat support B.1, B.4 B.2 the described chair back form triangular structure with described first bracing piece.
Further, described fixing chair B also comprises siphunculus in steel, and in described steel, siphunculus is located at the both sides at the described chair back B.2 rear, for arranging the described body surface indwelling tube of walking.
Further, described protective clothing C comprises: protective clothing body C.1, described protective clothing body C.1 back part offer expose animal back hole so that arrange described body surface indwelling tube, be provided with described protection box C.2 in the outside in described hole.
Further, C.3 C.2 described protection box be provided with openable bonnet.
Further, C.12 C.1 described protective clothing body be provided with steel plate in back part, and described hole is arranged on described steel plate and C.12 goes up, and C.12 C.2 described protection box be fixedly connected with described steel plate.
Further, described protective clothing C also comprises the parcel being separately positioned on the described protective clothing body C.1 left and right sides, and C.13 described parcel is provided with the stick that can mutually paste.
Further; described parcel comprise be arranged on described protective clothing body C.1 left side the first parcel C.9 with the second parcel C.10; and be arranged on described protective clothing body C.1 right side the 3rd parcel C.8; C.8, described 3rd parcel can be pasted onto described second parcel and C.10 go up, and C.9 described first parcel can be pasted onto described 3rd parcel and C.8 go up.
Further; described protective clothing C also comprises and is located at described protective clothing body C.1 the shoulder belt that extends forward of shoulder both sides is C.6; C.6 in described protective clothing body one end C.1, be provided with soft steel plate C.5 at described shoulder belt, described shoulder belt C.6 or bolt bonding with described parcel away from the described protective clothing body other end C.1 connects.
Further, also comprise by the overcoat worn after forward direction, for being set in described protective clothing body outside C.1.
Based on technique scheme; the non-human primate reflex action pilot system of the embodiment of the present invention; by arranging fixing chair in animal self administration Dynamic System case; supporting protective clothing can be put at the trial to animal; this protective clothing back is provided with the protection box holding body surface indwelling tube; by protection box is fixed on the chair back; just can be fixed protective clothing; and then realize fixing animal, and tested by the reflex action of various test equipments to animal in control box.Just can be met the various demands in process of the test by the pilot system of the whole series of the present invention comparatively all sidedly, simplify process of the test, thus can experimentation cost be reduced; And only just need can realize the fixing of health by the back of fixing animal in process of the test, do not limit four limbs freely movable, can monitor the behavior of animal more accurately.
Accompanying drawing explanation
Accompanying drawing described herein is used to provide a further understanding of the present invention, and form a application's part, schematic description and description of the present invention, for explaining the present invention, does not form inappropriate limitation of the present invention.In the accompanying drawings:
Fig. 1 is the perspective view of an animal self administration Dynamic System case embodiment in non-human primate reflex action pilot system of the present invention;
Fig. 2 is the structural representation of an embodiment of pedal module in the self administration of animal shown in Fig. 1 Dynamic System case;
Fig. 3 is the left view of the self administration of animal shown in Fig. 1 Dynamic System case;
Fig. 4 is the right view of the self administration of animal shown in Fig. 1 Dynamic System case.
Fig. 5 is the structural representation of an embodiment of the self administration of animal shown in Fig. 1 Dynamic System case median septum;
Fig. 6 is the structural representation that in non-human primate reflex action pilot system of the present invention, animal fixes an embodiment of chair;
Fig. 7 is the structural representation of protective clothing in non-human primate reflex action pilot system of the present invention.
In figure: A.1-dividing plate; A.2-proparea; A.3-back zone; A.4-baffle plate; A.5-storage compartment; A.6-intravenous injection automatic chemical feeding module; A.7-reacting record module; A.8-illuminating lamp; A.9-camera; A.10-formula crib is leant out; A.11-through wires hole; A.12-mounting platform; A.13-pedal box; A.14-pedal; A.15-lever; A.16-spring; A.17-chain; A.18-bore a hole; A.19-ventilating fan; A.20-movable pulley; A.21-slide rail;
B.1-seat support; B.2-the chair back; B.21-fixed head; B.22-sliding panel; B.23-chute; B.24-guard bar; B.25-pin; B.26-the first butterfly screw; B.3-the second butterfly screw; B.4-the first bracing piece; B.5-base plate; B.6-slider bar; B.7-the second bracing piece;
C.1-protective clothing body; C.2-box is protected; C.3-bonnet; C.4-pin-and-hole; C.5-soft steel plate; C.6-shoulder belt; C.61-bolt hole; C.7-bolt; C.8-the 3rd parcel; C.9-the first parcel; C.10-the second parcel; C.12-steel plate; C.13-stick.
Embodiment
Below describe the present invention in detail.In the following paragraphs, the different aspect of embodiment is defined in more detail.The each side of restriction like this can combine with any other one aspect or many aspects, not may be combined with unless explicitly stated otherwise.Especially, be considered to preferred or favourable any feature and one or morely can be considered to preferred or favourable feature with other.
Terms such as " first ", " second " that occur in the present invention is only for convenience of description, to distinguish the different building blocks with same names, does not represent successively or primary-slave relation.
In describing the invention; it will be appreciated that; term " on ", D score, "front", "rear", "left", "right", " vertically " and " level ", " interior ", the orientation of the instruction such as " outward " or position relationship be based on orientation shown in the drawings or position relationship; only the present invention for convenience of description; instead of the device of instruction or hint indication must have specific orientation, with specific azimuth configuration and operation, therefore can not be interpreted as limiting the scope of the invention.
The object of the invention is to study a set of pilot system being applicable to testing the reflex action of non-human primate; with the various operational requirements in short form test; and obtain result of the test comparatively accurately; such as can be fixed animal easily; protection body surface indwelling tube line; feeding or intravenous injection, fix monkey, protection indwelling pipeline, feeding, intravenous injection, facilitate animal operation and logging etc.
In one embodiment of the invention, as shown in Figures 1 to 7, non-human primate reflex action pilot system comprises: the animal self administration Dynamic System case A of complete setting, fixing chair B and protective clothing C, fixing chair B is located in control box A, and control box A is supporting is provided with the test equipment tested the reflex action of animal A.5; Fixing chair B comprise seat support B.1 with the chair back B.2; C.2 the back of protective clothing C is provided with the protection box of accommodation body surface indwelling tube; C.2, protection box can be fixed on the chair back and B.2 go up; for being C.2 fixed protective clothing C by protection box; and then realize fixing, A.5 to be tested the behavior of animal by test equipment animal.Wherein, animal is in waking state at the trial, and animal can prioritizing selection non-human primate, such as monkey or orangutan etc., and different types of monkey such as rhesus macaque, Lithodes monkey or macaque etc. can use this kind of pilot system.
Based on above-described embodiment; pilot system of the present invention; need to put on supporting protective clothing to animal at the trial, and by the protection box at back, body surface indwelling tube is protected, then make animal squat on seat support; protection box is fixed on the chair back simultaneously; so just limit the motion of animal bodies, be not easy to make animal to produce too strong Anxiety, and after animal leaves fixing chair; also can protect body surface indwelling tube, thus be suitable for prolonged and repeated test.By fixing protection box, just can be fixed protective clothing, and then realize fixing animal, and be tested by the reflex action of various test equipments to animal in control box.The various demands in process of the test just can be met comparatively all sidedly by this kind of pilot system, avoid in prior art type selecting is carried out to each independent part, trouble that matched interfaces, connection bring, considerably simplify process of the test, thus can experimentation cost be reduced; And only just need can realize the fixing of health by the back of fixing animal in process of the test, do not limit the freely activity of animal foot, can monitor the reaction of animal and behavior more accurately.
Be explained in detail to the major part of three in pilot system respectively below, and provide the annexation between various piece.
First, animal self administration Dynamic System case A is the agent structure of whole pilot system, the general structure schematic diagram of a control box embodiment as shown in Figure 1, each view shown in Fig. 2 to Fig. 5, control box A comprise control box main body, dividing plate A.1 with test equipment A.5, A.5, test equipment comprises signal stimulus module, reacting record modules A .7 and award module, wherein: A.1 dividing plate is positioned at control box body interior, and the inner space of control box main body is divided into proparea A.2 with back zone A.3, proparea is A.2 for placing fixing chair B; A.3 signal stimulus module is located at back zone, for carrying out environmental stimuli to animal; Reacting record modules A .7 is located at back zone A.3 or outside control box A, for carrying out record to the operation of animal; Award module is located at back zone A.3 or outside control box A, gives corresponding award for the operating data recorded according to reacting record modules A .7 to animal.
In this embodiment, by arranging dividing plate A.1, the inner space of control box A is divided into proparea A.2 with back zone A.3, wherein proparea is A.2 for placing animal, and other test equipment A.5, such as signal stimulus module, reacting record modules A .7 and award module can be placed on back zone A.3 or outside control box A, dividing plate is utilized A.1 animal and test equipment to be separated like this, make layout more reasonable, animal can be avoided to grab and to touch or destructive test equipment, the connection line of being correlated with is avoided to be dragged disconnected by animal, normally carrying out of impact test.
In order to detect and record the conditioned reflex sexual behavior of animal, animal self administration Dynamic System case A also comprises pedal module, pedal module is located at back zone A.3 or outside control box A, pedal module is connected with reacting record modules A .7 signal, for receiving the operation of animal to pedal module, and recorded the operating data of animal by reacting record modules A .7.
The specific implementation form of pedal module can have multiple choices, such as can allow animal pushes pedals, then records the number of times that pedal is pressed; Also can select more to meet the life of animal and the mode of action habit, allow animal pull chain etc.
In one embodiment, pedal module comprise pedal box A.13 with pedal A.14, A.13, A.3 pedal box is installed on back zone, pedal A.14 by elastic mechanism be installed on pedal box A.13 in, elastic mechanism can realize pedal reset A.14, A.13 pedal A.14 part exposes pedal box, and A.2 pedal exposed portion is A.14 positioned at proparea, presses to enable animal.
Pedal module in this embodiment A.13 pedal box can be arranged in back zone A.3 in, as long as A.2 A.14 pedal partly expose proparea, to enable animal, A.14 pedal is pressed; Can certainly A.13 pedal box be arranged in outside control box A, but this needs the linkage structure that bamboo product is relevant, A.2 pedal is pressed A.14 in proparea to make animal, A.13, the pedal box be positioned at outside control box A still can sense the number of times that A.14 pedal is pressed, and carry out record by reacting record modules A .7.
In another embodiment, as shown in Figure 2, A.12 the top outer of control box A is provided with mounting platform, pedal module is arranged at mounting platform and A.12 goes up, A.13 pedal module comprises pedal box, pedal A.14, lever A.15, spring A.16 with chain A.17, pedal A.14 by elastic mechanism be installed on pedal box A.13 in, elastic mechanism can realize pedal reset A.14, A.14, A.13 pedal partly exposes pedal box, lever one end is A.15 rotatably connected to mounting platform and A.12 goes up, the other end is overlapped on pedal exposed portion A.14, A.16, spring is arranged at mounting platform A.12 and between lever middle part A.15, chain be A.17 connected to spring A.16 with the junction at lever middle part A.15, chain A.17 through spring A.16 and hang on proparea A.2, pull to enable animal.A.18, perforation is located at spring end A.16, also can pull for animal, or A.18 A.17 chain can be fixed through perforation.
In this embodiment, when animal proparea A.2 in pull down drag chain A.17 time, A.15 be pulled with the lever that A.17 chain is connected, because lever one end A.15 and pedal exposed portion A.14 overlap mutually, therefore A.14 pedal is pressed in linkage, and namely reacting record modules A .7 records a secondary data.In addition, because A.16 spring is compressed, when animal leave chain A.17 after, lever is resilience under spring effect A.16 A.15, and A.14 pedal resets under the effect of elastic mechanism.
This life habit more being met animal by allow animal pull structure that chain records its behavioral trait, particularly concerning non-human primate, they have more responsive operation instinct for chain, and therefore this structure has universality more.In addition, pedal module can arrange two, with make animal pass through pressing left pedal or right-side pedal, left side chain or right side chain all can by reacting record modules A .7 record.
Award module comprises foodstuff delivery module and/or intravenous injection automatic chemical feeding modules A .6, wherein foodstuff delivery module is used for delivering food or drug particles to animal, intravenous injection automatic chemical feeding modules A .6 is used for the intravenous liquid medicine to animal, foodstuff delivery module and/or intravenous injection automatic chemical feeding modules A .6 are connected with reacting record modules A .7 signal, carry out feeding or automatic chemical feeding with the operating data recorded according to reacting record modules A .7 to animal.
Wherein, foodstuff delivery module can be arranged in back zone A.3 in, also can be arranged in outside control box A.Foodstuff delivery module can deliver food, tablet or drug particles etc. to animal.In described proparea, A.2 A.10 side is provided with the formula crib of leaning out, and to facilitate described animal to capture food, A.10 described foodstuff delivery module and the described formula crib that leans out cooperatively interact, with by lean out described in described food input formula crib A.10 in.In foodstuff delivery module, feeding passage can be set, A.10, this feeding passage coordinates with the formula crib of leaning out, A.10, feeding passage can directly be connected with the formula crib of leaning out, when foodstuff delivery module receives feeding instruction, namely foodstuff delivery module discharges food, food by feeding passage enter the formula crib of leaning out A.10 in; Certainly, A.10 feeding passage also directly can not be connected with the formula crib of leaning out, but is positioned at the formula crib of leaning out top A.10, when foodstuff delivery module release food time, food can just in time fall to the formula crib of leaning out A.10 in.Compared to existing embedded crib, A.10 the formula that the leans out crib in above-described embodiment advantageously carries out crawl food in animal.
Intravenous injection automatic chemical feeding modules A .6 comprises syringe pump and propulsive mechanism, and according to the operating data that reacting record modules A .7 records, intravenous injection automatic chemical feeding modules A .6 can control propulsive mechanism and apply to preset the amount of feeding to syringe pump.Wherein the concrete structure of propulsive mechanism can be selected according to actual conditions, such as can adopt cylinder or motor etc.
Intravenous injection automatic chemical feeding modules A .6 can be arranged at back zone A.3 in, also can be arranged at outside control box A, A.12 the mounting platform that such as can be arranged on control box A top outer is gone up, and is conducive to the administrations observing syringe pump at any time like this.
Be connected better with between animal to realize intravenous injection automatic chemical feeding modules A .6, intravenous injection automatic chemical feeding modules A .6 also comprises pipeline, and one end of pipeline is located in the skin surface of animal, and the other end is connected with syringe pump.The animal of generally doing experiment; such as monkey; that there is the non-human primate compared with high iq; its four limbs are comparatively flexible; if do not protected pipeline; be easy to be damaged by monkey; therefore after monkey being fixed; one end of pipeline can be located in monkey skin surface; then pipeline is passed from monkey posterior lumbar, special protective clothing C can also be put on to monkey, with fixing and protection pipeline; finally be connected with syringe pump with elasticity flexible metallic hose, namely achieve the connection of pipeline and intravenous injection automatic chemical feeding modules A .6.In order to prevent monkey from damaging the pipeline of walking in the process of test, siphunculus in steel can being set in the both sides at chair back rear B.2, for arranging the indwelling tube of walking, preventing monkey pawl from grabbing bad by pipeline.
In addition, A.2 described proparea can also be provided with indicator lamp or loudspeaker, and indicator lamp or loudspeaker are electrically connected with signal stimulus module, to carry out light or Sound stimulat to described animal.
The animal of test is as a kind of live body, need the life condition ensureing that it is basic, therefore need to create living condition comfortable as far as possible, such as can arrange on the tank wall A.2 of proparea air-vent, illuminating lamp A.8 with camera A.9, wherein air-vent is used for the A.2 ventilation of the proparea residing for animal, illuminating lamp is A.8 for providing illumination to animal, and A.9 camera can be used for recording the behavior act of animal.
As shown in Figure 1, A.11 A.2 proparea be also provided with through wires hole, be convenient to animal pipeline with it and back zone A.3 in correlation test equipment A.5 between connection.As shown in Figure 3 and Figure 4, A.19 the proparea 2 of control box A can also arrange ventilating fan, to accelerate the A.2 interior air exchange in proparea; A.20 the bottom of control box A can arrange movable pulley, the movement of handled easily case A.
As shown in Figure 5, at dividing plate, central authorities A.1 can arrange cavity, then A.4 this cavity is partly blocked with baffle plate, A.4, this baffle plate is positioned at side A.2, proparea can install the equipment such as indicator lamp or loudspeaker, A.4, A.5 baffle plate is positioned at side A.3, back zone can install various test equipment, and A.5 test equipment can comprise signal stimulus module, reacting record modules A .7 and award module etc.A.4, baffle plate can adopt corrosion resistant plate to make, and intensity is larger, avoids damaging due to the crawl of animal.
Be subject to the interference of ambient noise in order to avoid animal or avoid animal to cause noise pollution to external environment, A.1 control box main body and dividing plate all adopt acoustic material.
From Fig. 1, the two sides, front and back of this control box A is double door design, and compared to one-sided enabling, the design of double door makes door opening action more convenient, and take up room little, field range is wide.
A.5 etc. preferably, dividing plate is A.1 parallel with Qianmen, distance back door about 1/3rd length, and proparea is comparatively large, and for placing fixing chair B and animal, back zone is less, places test equipment.
By the above-mentioned multiple embodiments to animal self administration Dynamic System case of the present invention provided, can see that this kind of animal self administration Dynamic System case can save expensive import charges; Rationally distributed; More meet the size of domestic non-human primate; Produced the operation of rewarding effect by the action of animal crawl chain, more meet life and the action habit of non-human primate, contribute to training faster and form test operation custom.
Control box A of the present invention can with fixing chair B with the use of, fix chair B at the trial to need to put into control box A, conveniently fixing chair is pulled out along direction shown in arrow D in Fig. 6 to be fixed by animal, forward operation case A is to carry out data acquisition or performance testing again, also facilitate taking-up to carry out cleaning and tidying simultaneously, in proparea, bottom A.2 or both sides are also provided with holding section, holding section is for installing fixing chair B, and form slide construction with the respective outer side edges of fixing chair B relevant position, pull out or push proparea A.2 to enable fixing chair B.
For a kind of concrete structure, as shown in figures 1 to 6, below fixing chair B, B.6 base plate both sides B.5 arrange the slider bar of protrusion, B.6, this slider bar is snapped in control box A proparea A.2 both sides, bottom slide rail A.21, just by slider bar B.6 slide rail A.21 in motion slide along the depth direction of control box A to realize fixing chair B, B.6, slider bar is provided with a series of jack, can coordinate with the jack of control box A two bottom sides, according to animal body size, regulate fixing chair proparea A.2 in and dividing plate A.1 between longitudinal separation, after adjustment, chair B can will be fixed fastening by securing member, to make fixing chair B more firm.In other version, also guide rail or roller can be set in base plate both sides B.5, slide rail is set in control box A A.21, or B.5 base plate is exchanged setting with corresponding structure in control box A.
After the syndeton of mating part describing control box A and fixing chair B, the embodiment will fixing chair B be provided can adopting below.This kind of fixing chair B needs to support the use with protective clothing C of the present invention; as shown in Figure 7; C.2 the back central authorities of protective clothing C are provided with protection box; at the trial; need protective clothing C to be wrapped on the health of animal, adjusting to the suitable position stick C.13 fixation of degree of tightness, more C.13 the shoulder C.6 shoulder belt being walked around animal is fixed by stick; at this moment protect box to be C.2 positioned at the back of animal, the indwelling tube of animal body surface from protection box C.2 in pass to protect.
With this protective clothing C cooperatively, in one embodiment, as shown in Figure 6, fixing chair B comprises: seat support B.1 with the chair back B.2, B.5 B.2 the chair back arranged perpendicular to base plate, and B.1 seat support is fixed on chair back middle part B.2 or region, middle and lower part.And B.2 the chair back is provided with cavernous structure, cavernous structure is positioned at seat support B.1 top, can be C.2 suitable with protection box, for being C.2 fixed protective clothing C by protection box, and then realizes fixing animal.Wherein, cavernous structure adapts with protection box shape C.2; C.2, demand fulfillment protection box does not rotate in cavernous structure; preferably; C.2, protection box is square box, and correspondingly cavernous structure is square hole, and this fit shapes makes simple; and C.2 protection box can not rotate in cavernous structure, thus protective clothing C is reliablely and stablely fixed.
The fixing chair of the embodiment of the present invention; by the chair back B.2 on cavernous structure is set; can C.2 the protection box at protective clothing C back be fixed in this cavernous structure at the trial; thus C.2 protective clothing C is fixed by protection box; and then realize fixing animal, avoid animal bodies flexible rotating and cause indwelling tube to be tied a knot or damage.This kind of fixing chair B can be fixed the health of animal easily; be not destroyed to protect the indwelling tube of body surface; but do not limit the freely activity of neck and four limbs; and fixing chair B is open space; the open constriction of animal that makes in space is less; Long term Animal can be avoided in bond and cause anxiety or hinder the observation to surrounding environment, thus improving the accuracy of in test, the reflex action of animal being monitored, to obtain more real result of the test.
Operate conveniently in embodiment at one, B.2 the chair back offers cavernous structure from top, also comprises pin B.25, after C.2 protection box is pushed cavernous structure from chair back top B.2, carries out spacing to protection box upper end C.2.This embodiment is inserted after not needing that C.2 protection box is aimed at cavernous structure completely again; only need load protection box C.2 from the opening part of the chair back B.2 upper end; again B.25 pin is fixed; because the flexibility of non-human primate is high; it is very difficult for it will being positioned at exactly certain position; mounting means due to the present embodiment only needs the aligning realizing left and right directions, thus makes installation more convenient.For this embodiment, need protection box to be C.2 designed to shape wide or wide at the top and narrow at the bottom up and down, successfully C.2 protection box could be pushed cavernous structure from chair back upper end open B.2 from top.
In currently available technology, some generally do not possess height adjusting function for the seat of fixing monkey, can only be applicable to the monkey of particular range body weight, all need to redesign monkey fix chair for the monkey that build is bigger than normal or less than normal.Monkey for other import fixes chair, can only be applicable to the small-sized monkey that 1 ~ 2kg is heavy, be not suitable for the body size of domestic test with monkey, domestic test is rhesus macaque or Lithodes monkey with monkey, the general at least 3 ~ 5kg of body weight, rhesus macaque adult weight can increase to 8 ~ 9kg.
Thus in order to adapt to the non-human primate of different building shape size; fixing chair B is designed to adjustable for height form by an alternative embodiment of the invention; as shown in Figure 6; B.2, the chair back comprises: fixed head B.21 with sliding panel B.22; B.21, fixed head is provided with gathering sill from top; overall in " recessed " shape structure, B.22 sliding panel to be embedded in gathering sill and the Height Adjustment that can slide up and down to realize to protection box C.2 fixed position along gathering sill, and cavernous structure is located at sliding panel and B.22 goes up.
Preferably, B.22 sliding panel offers cavernous structure from top, also comprises pin B.25, after C.2 protection box is pushed cavernous structure from fixed head top B.21, carries out spacing to protection box upper end C.2.
In order to realize sliding panel B.22 in the position adjustment that B.21 fixed head is gone up, in a kind of version, can at sliding panel both sides B.22 design chute B.23, and by fixed head B.21 in two sides of gathering sill embed chutes B.23 in, B.22 B.21 steadily can regulate along fixed head to realize sliding panel.In another kind of version, also can fixed head B.21 on chute is set, and B.22 sliding panel to be embedded in chute.Further, after adjusting to the right place, need B.22 sliding panel to be reliably fixed on fixed head and B.21 go up, such as, at sliding panel, B.22 with in fixed head short transverse B.21 the hole of series of discrete can be set, after Height Adjustment puts in place, wear corresponding hole group by securing member be fixed; Can also sliding panel B.22 or fixed head B.21 on elongated hole is set to regulate continuously, and be B.26 fixed by the first butterfly screw, adopting butterfly screw to operate when tightening and unclamp comparatively convenient, can manually adjusting, without the need to coordinating other aid.
Preferably; for the chair back B.2 on offer the embodiment of cavernous structure or gathering sill, also guard bar can be set B.24, after being fixed by monkey; B.24, guard bar is overlapped on the upper end of gathering sill, can prevents monkey from being injured by the sharp-pointed portion of the chair back B.2 upper end in active procedure like this.
Achieve respectively in above-mentioned each embodiment and be C.2 fixed along the width of fixing chair B and short transverse protection box, further, also can arrange secure component, C.2 secure component moves along the fore-and-aft direction of fixing chair B for limiting protection box.In a kind of concrete version, as shown in Figure 7, C.2 go up at protection box and offer upper and lower two parallel pin-and-holes in the horizontal direction C.4, also offer hole in the position that sliding panel side is B.22 C.4 corresponding to pin-and-hole simultaneously, when protecting box to be C.2 embedded in cavernous structure completely, insert with L shape pin and C.2 move along the fore-and-aft direction of fixing chair B to limit protection box, or it is spacing also the securing member of other type can be adopted to carry out, C.2, such protection box is all limited along the one-movement-freedom-degree of any direction, thus can reliably be fixed protective clothing C, and then realize fixing the reliable of animal, thus avoid the fixing chair of employing waist hole fixed forms more of the prior art, make the mobility of monkey large, easily damage because rotating excessively the pipeline connecting monkey health.
In another embodiment of fixing chair B, B.1 seat support can slide up and down to be located at chair back side B.2 to realize seat support Height Adjustment B.1.This embodiment can make fixing chair B adapt to the monkey of different building shape more neatly; can with sliding panel adjustment B.22 with the use of; sliding panel moving up and down B.22 can realize the adjustment to protection box C.2 fixed position; and seat support moving up and down B.1 can realize squatting to monkey the adjustment of height; such as; for the monkey that build is less, at the trial in order to get at the chain at control box A top A.17, just need seat support B.1 to heighten.Wherein, B.1 seat support can be designed as slab construction, also can form platform by some steel-pipe weldings.Preferably, damaged by the aggravating activities of Adult Monkey because intensity is not enough to prevent fixing chair B, whole fixing chair all B useful steel materials is made, to ensure enough intensity, particularly, built the frame structure of whole fixing chair B by steel-pipe welding, comprise fixed head B.21, B. seat support 21 and base plate B.5, B.22 sliding panel adopts steel plate.
In order to increase the intensity of fixing chair B further, in a preferred embodiment, B.4 fixing chair B also can arrange two the first bracing pieces, each first bracing piece one end is B.4 connected with seat support free end B.1, the other end can slide up and down to be connected to the chair back and B.2 go up, and seat support B.1, B.4 the chair back B.2 with the first bracing piece form triangular structure.B.1 can reliably fix after the adjustment of position in order to ensure seat support, can seat support B.1 two ends and two the first bracing pieces 4 with chair back junction B.2, the second butterfly screw is set B.3, after adjusting to the right place, B.3 the second butterfly screw is screwed.Further, two the second bracing pieces also can be set B.7, each second bracing piece one end is B.7 connected with base plate free end B.5, the other end is connected to the chair back and B.2 goes up, thus make base plate B.5, B.7 the chair back B.2 with the second bracing piece form triangular structure, thus increases the non-deformability of fixing chair.
In addition, also can tray drawn along axis type being set in the bottom of fixing chair B, for accessing excreta or other dirt of animal in process of the test, sweeping cleaning to facilitate, keep clean and tidy.
Next be described in detail to the protective clothing C in pilot system of the present invention.With reference to the structural representation of the protective clothing shown in figure 7; in one embodiment; protective clothing C comprises: protective clothing body C.1, protective clothing body C.1 back part offer expose animal back hole so that arrange body surface indwelling tube, be provided with in the outside in hole protection box C.2.
Because back is the place that animal is difficult to touch most, by offering the hole of exposing animal back at the back part of protective clothing body, body surface indwelling tube is set, animal cannot be touched be positioned at the body surface indwelling tube of back, and be provided with in the outside in hole hold body surface indwelling tube protection box C.2 as the outlet of body surface indwelling tube, body surface indwelling tube can be contained in protection box C.2 in, even if animal has body surface indwelling tube when moving by a small margin still can remain unaffected, but also C.2 can fix animal by fixing protection box, compared to the mode that the four limbs of animal are fixed, the anxious state of mind of animal is less, animal more independently can express its response situation by four limbs activity, the test value obtained more can close to actual value, there is higher exploitativeness.
Preferably; C.2, protection box is openable structure; box is such as protected C.2 to be provided with openable bonnet C.3; covering after opening can so that the All other routes such as adjustment or dismounting body surface indwelling tube C.3; protect the C.2 interior body surface indwelling tube of box can be connected with external infusion organ pipe; iron pipe and Universal rotary assembly need not be used, cost-saving.Protection box C.2 go up can arrange bolt C.7 ensure bonnet be C.3 fixedly installed on protection box C.2 on protection box C.2 in body surface indwelling tube.
As a more excellent embodiment; C.1, C.12 protective clothing body is provided with steel plate in back part; hole is arranged on steel plate and C.12 goes up; C.2, C.12 protection box is fixedly connected with steel plate; by establishing steel plate C.12 in protective clothing body C.1 back part; the back of animal can be flattened on steel plate, is convenient to arrange body surface indwelling tube from the position being arranged on steel plate and C.12 hole and tests.
On the basis of each embodiment above-mentioned, protective clothing C also comprises the parcel being separately positioned on the protective clothing body C.1 left and right sides, and C.13 parcel is provided with the stick that can mutually paste.As shown in Figure 7; protective clothing C is designed to the version of similar vest shape; so that animal dress; protective clothing C front portion is left and right chip, adopts horizontally disposed multiple tracks stick C.13 to paste, and can adjust arbitrarily the tightness of protective clothing C parcel according to animal shape size; to ensure that protective clothing C is next to the skin fixing; there is higher adjustability, and there is not the problem of the chaeta obstruction that slide fastener causes, for animal provides comfortable experimental enviroment.
More specifically; parcel comprise be located at protective clothing body C.1 left side the first parcel C.9 with the second parcel C.10; and be located at protective clothing body C.1 right side the 3rd parcel C.8; C.8,3rd parcel can be pasted onto the second parcel and C.10 go up; C.9, first parcel can be pasted onto the 3rd parcel and C.8 go up, by arrange three layers successively left and right paste parcel, paste more firm; improve the difficulty that animal tears parcel, there is higher reliability.Certainly, the structure of pasting successively more multi-layered left and right can also be set and obtain better fixed performance.
As the further improvement to above preferred embodiment, protective clothing C also can be included in protective clothing body, and C.1 the shoulder belt that extends forward of shoulder both sides is C.6, C.6 in protective clothing body one end C.1, soft steel plate is provided with C.5 at shoulder belt, shoulder belt is C.6 bonding with parcel away from the protective clothing body other end C.1, or C.91 the bolt hole C.61 to arrange with the first parcel 9 by arranging bolt hole coordinates and realizes bolt and be connected, shoulder belt setting C.6 can make protective clothing C wrap up animal more securely, and C.5 soft steel plate can prevent animal from biting shoulder belt broken C.6, reduce destroyed possibility.
Improve as to a step again of above preferred embodiment; protective clothing C also can by the overcoat worn after forward direction; also counter wearing the clothes can be called; for being set in protective clothing body outside C.1; overcoat is by being set in protective clothing body C.1 outside after forward direction, at back, place is connected, and animal cannot touch back to untie overcoat; further increasing animal tears the difficulty of parcel, further improves the fastening reliability of protective clothing.
For the pilot system adopted in reality, the maximum contour dimension (long × wide × high) of control box A is 74 × 84 × 124cm, and operating space is large, prevents animal from affecting result of the test because narrow space causes its anxiety nervous.The maximum contour dimension (long × wide × high) being arranged on the fixing chair B in control box A is 55 × 30 × 73cm, and the space of actual monkey activity is greater than this size.
Above a kind of non-human primate reflex action pilot system provided by the present invention is described in detail.Apply specific embodiment herein to set forth principle of the present invention and embodiment, the explanation of above embodiment just understands method of the present invention and core concept thereof for helping.It should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention, can also carry out some improvement and modification to the present invention, these improve and modify and also fall in the protection domain of the claims in the present invention.

Claims (20)

1. a non-human primate reflex action pilot system, is characterized in that, comprising: animal self administration Dynamic System case (A), fixing chair (B) and protective clothing (C),
Described fixing chair (B) is located in described control box (A), and described control box (A) is supporting is provided with the test equipment (A.5) tested the reflex action of animal;
Described fixing chair (B) comprises seat support (B.1) and the chair back (B.2); the back of described protective clothing (C) is provided with the protection box (C.2) holding body surface indwelling tube; described protection box (C.2) can be fixed on the described chair back (B.2); for being fixed described protective clothing (C) by described protection box (C.2); and then realize fixing, to be tested by described test equipment (A.5) behavior to described animal described animal.
2. non-human primate reflex action pilot system according to claim 1, it is characterized in that, described control box (A) also comprises control box main body and dividing plate (A.1), described test equipment (A.5) comprises signal stimulus module, reacting record module (A.7) and award module, wherein:
Described dividing plate (A.1) is positioned at described control box body interior, and the inner space of described control box main body is divided into proparea (A.2) and back zone (A.3), described proparea (A.2) is for placing described fixing chair (B);
Described signal stimulus module is located at described back zone (A.3), for carrying out environmental stimuli to described animal;
Described reacting record module (A.7) is located at described back zone (A.3) or described control box (A) outward, for carrying out record to the operation of described animal;
Described award module is located at described back zone (A.3) or described control box (A) outward, gives corresponding award for the operating data recorded according to described reacting record module (A.7) to described animal.
3. non-human primate reflex action pilot system according to claim 2, it is characterized in that, described control box (A) also comprises pedal module, described pedal module is located at described back zone (A.3) or described control box (A) outward, described pedal module is connected with described reacting record module (A.7) signal, for receiving the operation of described animal to described pedal module, and recorded the operating data of described animal by described reacting record module (A.7).
4. non-human primate reflex action pilot system according to claim 3, it is characterized in that, described pedal module comprises pedal box (A.13) and pedal (A.14), described pedal box (A.13) is installed on described back zone (A.3), described pedal (A.14) is installed in described pedal box (A.13) by elastic mechanism, described elastic mechanism can realize the reset of described pedal (A.14), described pedal (A.14) part exposes described pedal box (A.13), the exposed portion of described pedal (A.14) is positioned at described proparea (A.2), press to enable described animal.
5. non-human primate reflex action pilot system according to claim 3, it is characterized in that, the top outer of described control box (A) is provided with mounting platform (A.12), described pedal module is arranged on described mounting platform (A.12), described pedal module comprises pedal box (A.13), pedal (A.14), lever (A.15), spring (A.16) and chain (A.17), described pedal (A.14) is installed in described pedal box (A.13) by elastic mechanism, described elastic mechanism can realize the reset of described pedal (A.14), described pedal (A.14) partly exposes described pedal box (A.13), one end of described lever (A.15) is rotatably connected on described mounting platform (A.12), the other end is overlapped on the exposed portion of described pedal (A.14), described spring (A.16) is arranged between the middle part of described mounting platform (A.12) and described lever (A.15), described chain (A.17) is connected to the junction at the middle part of described spring (A.16) and described lever (A.15), described chain (A.17) is through described spring (A.16) and hang on described proparea (A.2), pull to enable described animal.
6. non-human primate reflex action pilot system according to claim 3, it is characterized in that, described award module comprises foodstuff delivery module and/or intravenous injection automatic chemical feeding module (A.6), wherein said foodstuff delivery module is used for delivering food or drug particles to described animal, described intravenous injection automatic chemical feeding module (A.6) is for the intravenous liquid medicine to described animal, described foodstuff delivery module and/or described intravenous injection automatic chemical feeding module (A.6) are connected with described reacting record module (A.7) signal, with the operating data recorded according to described reacting record module (A.7), feeding or automatic chemical feeding are carried out to described animal.
7. non-human primate reflex action pilot system according to claim 6, it is characterized in that, described intravenous injection automatic chemical feeding module (A.6) comprises syringe pump and propulsive mechanism, according to the operating data that described reacting record module (A.7) is recorded, described intravenous injection automatic chemical feeding module (A.6) can control described propulsive mechanism and apply to preset the amount of feeding to described syringe pump.
8. non-human primate reflex action pilot system according to claim 2, it is characterized in that, the proparea (A.2) of described control box (A) is also provided with indicator lamp or loudspeaker, described indicator lamp or loudspeaker are electrically connected with described signal stimulus module, to carry out light or Sound stimulat to described animal.
9. non-human primate reflex action pilot system according to claim 2, it is characterized in that, bottom or the both sides in described proparea (A.2) are also provided with holding section, described holding section is for installing described fixing chair (B), and form slide construction with the respective outer side edges of described fixing chair (B) relevant position, can pull out or push described proparea (A.2) to make described fixing chair (B).
10. non-human primate reflex action pilot system according to claim 1; it is characterized in that; the described chair back (B.2) is provided with cavernous structure; described cavernous structure is positioned at described seat support (B.1) top; can be suitable with described protection box (C.2); for being fixed described protective clothing (C) by described protection box (C.2), and then realize fixing described animal.
11. non-human primate reflex action pilot systems according to claim 10; it is characterized in that; the described chair back (B.2) offers described cavernous structure from top; also comprise pin (B.25); after described protection box (C.2) is pushed described cavernous structure from the top of the described chair back (B.2), carry out spacing to the upper end of described protection box (C.2).
12. according to the arbitrary described non-human primate reflex action pilot system of claim 10 ~ 11; it is characterized in that; described fixing chair (B) also comprises secure component, and described secure component moves along the fore-and-aft direction of described fixing chair (B) for limiting described protection box (C.2).
13. according to the arbitrary described non-human primate reflex action pilot system of claim 10 ~ 11, it is characterized in that, described seat support (B.1) can slide up and down to be located at the side of the described chair back (B.2) to realize the Height Adjustment of described seat support (B.1).
14. non-human primate reflex action pilot systems according to claim 13, it is characterized in that, described fixing chair (B) also comprises two the first bracing pieces (B.4), one end of each described first bracing piece (B.4) is connected with the free end of described seat support (B.1), the other end can slide up and down to be connected on the described chair back (B.2), and described seat support (B.1), the described chair back (B.2) and described first bracing piece (B.4) form triangular structure.
15. non-human primate reflex action pilot systems according to claim 1; it is characterized in that; described protective clothing (C) comprising: protective clothing body (C.1); described protective clothing body (C.1) back part offer expose animal back hole so that arrange described body surface indwelling tube, be provided with described protection box (C.2) in the outside in described hole.
16. non-human primate reflex action pilot systems according to claim 15; it is characterized in that; steel plate (C.12) is provided with in described protective clothing body (C.1) back part; described hole is arranged on described steel plate (C.12), and described protection box (C.2) is fixedly connected with described steel plate (C.12).
17. non-human primate reflex action pilot systems according to claim 15; it is characterized in that; described protective clothing (C) also comprises the parcel being separately positioned on described protective clothing body (C.1) left and right sides, and described parcel is provided with the stick (C.13) that can mutually paste.
18. non-human primate reflex action pilot systems according to claim 17; it is characterized in that; described parcel comprises the first parcel (C.9) and the second parcel (C.10) that are arranged on described protective clothing body (C.1) left side; and be arranged on the 3rd parcel (C.8) on described protective clothing body (C.1) right side; described 3rd parcel (C.8) can be pasted onto on described second parcel (C.10), and described first parcel (C.9) can be pasted onto in described 3rd parcel (C.8).
19. non-human primate reflex action pilot systems according to claim 18; it is characterized in that; described protective clothing (C) also comprises the shoulder belt (C.6) being located at described protective clothing body (C.1) shoulder both sides and extending forward; in one end of described protective clothing body (C.1), be provided with soft steel plate (C.5) at described shoulder belt (C.6), away from the other end of described protective clothing body (C.1), or bolt bonding with described parcel connects described shoulder belt (C.6).
20. non-human primate reflex action pilot systems according to claim 15, is characterized in that, also comprise by the overcoat worn after forward direction, for being set in the outside of described protective clothing body (C.1).
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