CN105381386A - Compound preparation for treating superficial gastritis - Google Patents

Compound preparation for treating superficial gastritis Download PDF

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Publication number
CN105381386A
CN105381386A CN201510957376.6A CN201510957376A CN105381386A CN 105381386 A CN105381386 A CN 105381386A CN 201510957376 A CN201510957376 A CN 201510957376A CN 105381386 A CN105381386 A CN 105381386A
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parts
rhizoma
radix
compound preparation
superficial gastritis
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冉德焕
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Jinan Haoze Environmental Protection Science & Technology Co Ltd
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Jinan Haoze Environmental Protection Science & Technology Co Ltd
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532Agastache, e.g. giant hyssop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/74Rubiaceae (Madder family)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
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    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
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    • A61K36/88Liliopsida (monocotyledons)
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    • A61K36/9064Amomum, e.g. round cardamom

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Abstract

The invention belongs to the technical field of traditional Chinese medicine treatment, and particularly relates to a compound preparation for treating superficial gastritis. The compound preparation for treating the superficial gastritis is prepared from afterbirth, semen raphani, rhizoma corydalis, ginseng, fructus amomi rotundus, agastache rugosus, bulbus fritillariae thunbergii, rhizoma pinelliae, stems of noble dendrobium, rhizoma galangae, radix ophiopogonis, fructus gardenia and radix aucklandiae. The traditional Chinese medicine has the effects of astringing, relieving hyperacidity, activating Qi and eliminating phlegm, promoting blood circulation to arrest pain, nourishing Yin for repairing, clearing heat and removing toxicity and invigorating the spleen to remove dampness.

Description

A kind of compound preparation for the treatment of superficial gastritis
Technical field
The invention belongs to the technical field for the treatment of by Chinese herbs, be specifically related to a kind of compound preparation for the treatment of superficial gastritis.
Background technology
Chronic gastritis is the gastric mucosa chronic inflammatory disease caused by the various cause of disease, is mainly divided into shallow, atrophic, particularity three major types.Clinical main manifestations is upper abdominal pain or discomfort, big belly, early full, belch, the indigestion symptom such as to feel sick.Current doctor trained in Western medicine is mainly based on antibacterial, acid suppression or antacid, short gastrointestinal motivity medicine, and its therapeutic effect is unsatisfactory, and these medicine side effect are large, very easily cause patient's inappetence, dyspepsia etc.
Summary of the invention
The object of the invention is to the defect for above-mentioned existence and provide a kind of compound preparation for the treatment of superficial gastritis, this Chinese medicine convergence, antacid, promoting the circulation of QI and reducing phlegm, promoting blood circulation and stopping pain, yin nourishing reparation, heat-clearing and toxic substances removing, invigorating spleen to remove dampness.
Technical scheme of the present invention is: a kind of compound preparation for the treatment of superficial gastritis, comprises the raw material of following weight portion: afterbirth 60-90 parts, Semen Raphani 30-60 parts, Rhizoma Corydalis 60-90 parts, Radix Ginseng 30-60 parts, 90-150 parts, Fructus Amomi Rotundus, Herba Pogostemonis 60-90 parts, Bulbus Fritillariae Thunbergii 30-60 parts, the Rhizoma Pinelliae 24-45 parts, Herba Dendrobii 60-90 parts, Rhizoma Alpiniae Officinarum 60-90 parts, Radix Ophiopogonis 60-90 parts, Fructus Gardeniae 60-120 parts, the Radix Aucklandiae 60-90 parts.
The compound preparation of described treatment superficial gastritis, comprises the raw material of following weight portion: afterbirth 60-80 parts, Semen Raphani 30-50 parts, Rhizoma Corydalis 60-85 parts, Radix Ginseng 30-50 parts, 90-125 parts, Fructus Amomi Rotundus, Herba Pogostemonis 60-80 parts, Bulbus Fritillariae Thunbergii 30-45 parts, the Rhizoma Pinelliae 30-45 parts, Herba Dendrobii 60-85 parts, Rhizoma Alpiniae Officinarum 60-85 parts, Radix Ophiopogonis 60-85 parts, Fructus Gardeniae 60-100 parts, the Radix Aucklandiae 60-80 parts.
The compound preparation of described treatment superficial gastritis, comprises the raw material of following weight portion: afterbirth 75 parts, Semen Raphani 45 parts, Rhizoma Corydalis 75 parts, Radix Ginseng 45 parts, 120 parts, Fructus Amomi Rotundus, Herba Pogostemonis 75 parts, Bulbus Fritillariae Thunbergii 40 parts, the Rhizoma Pinelliae 30 parts, Herba Dendrobii 75 parts, Rhizoma Alpiniae Officinarum 75 parts, Radix Ophiopogonis 75 parts, Fructus Gardeniae 75 parts, the Radix Aucklandiae 75 parts.
The compound preparation of described treatment superficial gastritis, comprises the raw material of following weight portion: afterbirth 60 parts, Semen Raphani 30 parts, Rhizoma Corydalis 60 parts, Radix Ginseng 30 parts, 90 parts, Fructus Amomi Rotundus, Herba Pogostemonis 60 parts, Bulbus Fritillariae Thunbergii 30 parts, the Rhizoma Pinelliae 24 parts, Herba Dendrobii 60 parts, Rhizoma Alpiniae Officinarum 60 parts, Radix Ophiopogonis 60 parts, Fructus Gardeniae 60 parts, the Radix Aucklandiae 60 parts.
The compound preparation of described treatment superficial gastritis, comprises the raw material of following weight portion: afterbirth 90 parts, Semen Raphani 60 parts, Rhizoma Corydalis 90 parts, Radix Ginseng 60 parts, 150 parts, Fructus Amomi Rotundus, Herba Pogostemonis 90 parts, Bulbus Fritillariae Thunbergii 60 parts, the Rhizoma Pinelliae 45 parts, Herba Dendrobii 90 parts, Rhizoma Alpiniae Officinarum 90 parts, Radix Ophiopogonis 90 parts, Fructus Gardeniae 120 parts, the Radix Aucklandiae 90 parts.
The compound preparation of described treatment superficial gastritis, comprises the raw material of following weight portion: afterbirth 80 parts, Semen Raphani 50 parts, Rhizoma Corydalis 85 parts, Radix Ginseng 50 parts, 125 parts, Fructus Amomi Rotundus, Herba Pogostemonis 80 parts, Bulbus Fritillariae Thunbergii 45 parts, the Rhizoma Pinelliae 30 parts, Herba Dendrobii 85 parts, Rhizoma Alpiniae Officinarum 85 parts, Radix Ophiopogonis 85 parts, Fructus Gardeniae 100 parts, the Radix Aucklandiae 80 parts.
Beneficial effect of the present invention is: the compound preparation for the treatment of superficial gastritis of the present invention, comprises following raw material: afterbirth, Semen Raphani, Rhizoma Corydalis, Radix Ginseng, Fructus Amomi Rotundus, Herba Pogostemonis, Bulbus Fritillariae Thunbergii, the Rhizoma Pinelliae, Herba Dendrobii, Rhizoma Alpiniae Officinarum, Radix Ophiopogonis, Fructus Gardeniae, the Radix Aucklandiae.
Afterbirth: Gan Xian, temperature.There is QI invigorating, nourish blood, effect of benefit essence.
Semen Raphani: pungent, bitter, sweet, puckery, be slightly cold; Return lung, liver, stomach warp; Blood circulation promoting and blood stasis dispelling; Protection gastric mucosa.
Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature; Invigorate blood circulation, promoting the circulation of QI, pain relieving, diuresis; The stagnation of QI in energy promoting the circulation of blood, stasis in gas; Cure mainly stomachache, dysmenorrhea, traumatic injury etc.
Radix Ginseng: sweet, temperature, nontoxic.Cure mainly trusted subordinate's cold air, children's's five kinds of child malnutrition, wards off epidemic disease, controls hemorrhoidal hamorrhage, tonneau gaseous pulse, and woman's blood closes.
Fructus Amomi Rotundus: salty, puckery, temperature; Return spleen, kidney channel.Astringing to arrest bleeding, relieving leukorrhea by astringents, antacid, sore.For Peptic Ulcers, hyperchlorhydria, stomachache acid regurgitation.Dehumidifying, antacid, hemostasis, sore.
Herba Pogostemonis: salty, is slightly cold; Return liver, gallbladder, kidney channel; Suppressing the hyperactive liver to relieve the wind syndrome; Yin nourishing; There is the effect restraining astringent or styptic treatment for spontaneous sweating deacidification, treatment have a stomach-ache, hyperchlorhydria etc., be antacid, have stomach function regulating analgesic activity.
Bulbus Fritillariae Thunbergii: bitter in the mouth; Cold in nature; Return lung, heart channel; Removing heat-phlegm; Sending down the abnormal ascending QI cough-relieving; Mass dissipating and swelling eliminating.
The Rhizoma Pinelliae: pungent, temperature; Enter spleen, stomach warp; Pungent loose warm-dryness syndrome is poisonous, main enter taste double enter lung, double cold expelling warm in nature, water of manageing it wets, lowering the adverse flow of QI, and kind taste damp-phlegm of dispelling, the kind nausea and vomiting controlling adverse rising of stomach-QI.Inverse gas falls then harmonization of the stomach and feeling of fullness vomiting from only, therefore is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the good medicine of dissolving lump and resolving mass.
Herba Dendrobii: be slightly cold; Sweet; Return stomach, kidney channel; Reinforcing stomach reg fluid, nourishing YIN and clearing away heat; Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision; Herba Dendrobii has excitation to intestinal tube, and shrinkage amplitude can be made to increase.
Rhizoma Alpiniae Officinarum: sweet in the mouth; Micro-hardship; Cold nature; Attach to the lung and stomach meridians; Accumulation of blood shies gas, except cold and heat, and invigorating middle warmer, lung benefiting gas; Treat stomach numbness cardiac and abdominal pain, stagnation of pathogenic heat pathogen is had a headache, pathogenic heat between skin, settling five organs; The sharp people of clothes of a specified duration.
Radix Ophiopogonis: sweet in the mouth, micro-hardship, be slightly cold; GUIXIN, lung, stomach warp; YIN nourishing and the production of body fluid promoting; Reinforcing stomach reg fluid; Be apt to control deficiency of stomach-Yin, dry tongue is thirsty, indigestion and loss of appetite not hungry card such as grade.In addition, also availablely deficiency of YIN dryness of the intestine is controlled, constipation person.
Fructus Gardeniae: sweet in the mouth; Bitterness; Great Cold; Heat clearing away, promote the production of body fluid, moisturize, laxation, pain relieving, removing heat from blood, hemostasis; There is YIN nourishing and the production of body fluid promoting effect; Thirsty for Tianjin wound, interior-heat is quenched one's thirst; Control epidemic febrile disease impairment of YIN, dryness of the intestine constipation.
The Radix Aucklandiae: sweet in the mouth, property is put down; Return spleen, lung meridian; Matter profit gas and, have strengthening the spleen and tonifying the lung, benefiting QI and nourishing blood promotes the production of body fluid, and cures mainly weakness of the spleen and stomach, anorexia and loose stool, and fatigue and weakness is thirsty.Strengthen passive protective physical fitness, reduce blood pressure, nourish blood, invigorating the spleen and replenishing QI.
In medicament composing prescription of the present invention, all medicines are harmonious, convergence, antacid, promoting the circulation of QI and reducing phlegm, promoting blood circulation and stopping pain, yin nourishing reparation, heat-clearing and toxic substances removing, invigorating spleen to remove dampness.
The compound preparation that the present invention treats superficial gastritis is under instruction of Chinese Medicine theory, concentrate on studies, sum up and form, adopt the method for convergence, antacid, promoting the circulation of QI and reducing phlegm, promoting blood circulation and stopping pain, yin nourishing reparation, invigorating spleen to remove dampness, focus on convergence, antacid, promoting blood circulation and stopping pain, yin nourishing reparation, above formula is reasonable, science, preparation method is simple, and cure rate high, not easily recur, have no side effect.
Clinical trial is carried out to the compound preparation for the treatment of superficial gastritis of the present invention below as follows:
Chronic gastritis is the gastric mucosa chronic inflammatory disease caused by the various cause of disease, is mainly divided into shallow, atrophic, particularity three major types.Clinical main manifestations is upper abdominal pain or discomfort, big belly, early full, belch, the indigestion symptom such as to feel sick.
Clinical report is as follows:
1, data and method
1.1 physical data
Be selected from patient 200 example, be divided into treatment group 100 example by random digits table, matched group 100 example.Wherein treatment group man 23 example, female 25 example, 18 ~ 66 years old age (median 47.5 years old), the course of disease 8 ~ 200 months (median 6 months).Matched group man 24 example, female 22 example, 24 ~ 63 years old age (median 50 years old), the course of disease 12 ~ 150 months (median 9 months).Two groups of patients comparing difference not statistically significant (P>0.05) in sex, age, the course of disease, severity extent etc., has comparability.
2, diagnostic criteria:
Western medicine diagnose reference the 8th edition " diagnostics ", tcm diagnosis and dialectical and typing reference " tcm diagnosis treatment standard ".
2.1 inclusive criterias:
Meet diagnostic criteria; Age was at 20 ~ 70 years old; The course of disease 1 ~ 28 year;
2.2 observation index:
With reference to the Syndrome Scale standard listed in " new Chinese medicine guideline of clinical investigations " for 2002, symptom seen in clinical (upper abdominal pain, abdominal distention, feel sick) every by light, in, 2 points heavily respectively, 4 points, 6 points; Symptom seen in clinical (epigastric discomfort, early full, belch) every by light, in, 1 point heavily respectively, 3 points, 5 points, before and after treatment, step by step calculation also records total mark, observed and recorded tongue picture, pulse condition but do not score.
2.3 criterions of therapeutical effect:
With reference to the card marquis curative effect determinate standard in " new Chinese medicine guideline of clinical investigations ".Effective: entirely to disappear or significantly alleviate, symptom integral reduces >=70%; Effective: original symptom takes a turn for the better to some extent or alleviates, symptom integral reduces >=30% but <70%; Invalid: original symptom is without improvement, and symptom integral reduces < 30%.
3 results:
Two groups of Comparison of therapeutic
Group Number of cases Effective Effectively Invalid
Treatment group 100 89 10 1
Matched group 100 45 23 32
Result shows: treatment group: effective 89 examples, effective 10 examples, invalid 1, total effective rate 99%.Matched group: effective 45 examples, effective 40 examples, invalid 15, total effective rate 85%.
Detailed description of the invention
Below by embodiment, the present invention will be described in detail.
Embodiment 1:
Afterbirth 75g, Semen Raphani 45g, Rhizoma Corydalis 75g, Radix Ginseng 45g, Fructus Amomi Rotundus 120g, Herba Pogostemonis 75g, Bulbus Fritillariae Thunbergii 40g, Rhizoma Pinelliae 30g, Herba Dendrobii 75g, Rhizoma Alpiniae Officinarum 75g, Radix Ophiopogonis 75g, Fructus Gardeniae 75g, Radix Aucklandiae 75g.
Ground top as powder, each serving with 20g, every day three times, warm water is taken after mixing it with water.
Grandson so-and-so, female, 56 years old, people from Tai'an, Shandong Province, suffered from chronic gastritis more than 26 years, and through western medicine routine treatment, poor effect, come here and go to a doctor, take embodiment 1, serve on 8 doses, after treatment, transference cure does not recur.
Week so-and-so, man, 65 years old, people from Tai'an, Shandong Province, suffered from chronic gastritis more than 28 years, and through western medicine routine treatment, poor effect, come here and go to a doctor, take embodiment 1, serve on 6 doses, after treatment, transference cure does not recur.
Embodiment 2
Afterbirth 75g, Semen Raphani 45g, Rhizoma Corydalis 60g, Radix Ginseng 45g, Fructus Amomi Rotundus 90g, Herba Pogostemonis 75g, Bulbus Fritillariae Thunbergii 40g, Rhizoma Pinelliae 30g, Herba Dendrobii 75g, Rhizoma Alpiniae Officinarum 75g, Radix Ophiopogonis 75g, Fructus Gardeniae 75g, Radix Aucklandiae 75g.
Ground top as powder, each serving with 20g, every day three times, warm water is taken after mixing it with water.
Qiu so-and-so, female, 23 years old, people from Mengyin County, Shandong Province, suffered from chronic more than 5 years, through western medicine routine treatment, poor effect, come here go to a doctor, take embodiment 2, serve on 5 doses, treatment after transference cure, advise again take 3 doses prevent recurrence.
Embodiment 3:
Afterbirth 75g, Semen Raphani 45g, Rhizoma Corydalis 75g, Radix Ginseng 45g, Fructus Amomi Rotundus 90g, Herba Pogostemonis 75g, Bulbus Fritillariae Thunbergii 40g, Rhizoma Pinelliae 30g, Herba Dendrobii 75g, Rhizoma Alpiniae Officinarum 75g, Radix Ophiopogonis 75g, Fructus Gardeniae 75g, Radix Aucklandiae 75g.
Ground top as powder, each serving with 20g, every day three times, warm water is taken after mixing it with water.
High so-and-so, female, 45 years old, people from Tai'an, Shandong Province, suffered from chronic gastritis more than 10 years, and through western medicine routine treatment, poor effect, come here and go to a doctor, take embodiment 3, serve on 7 doses, after treatment, transference cure does not recur.
Embodiment 4:
Afterbirth 75g, Semen Raphani 30g, Rhizoma Corydalis 60g, Radix Ginseng 45g, Fructus Amomi Rotundus 90g, Herba Pogostemonis 75g, Bulbus Fritillariae Thunbergii 40g, Rhizoma Pinelliae 30g, Herba Dendrobii 75g, Rhizoma Alpiniae Officinarum 75g, Radix Ophiopogonis 75g, Fructus Gardeniae 75g, Radix Aucklandiae 75g.
Ground top as powder, each serving with 20g, every day three times, warm water is taken after mixing it with water.
Lee so-and-so, man, 24 years old, people from Tai'an, Shandong Province, suffered from chronic more than 6 years, through western medicine routine treatment, poor effect, come here go to a doctor, take embodiment 4, serve on 5 doses, treatment after transference cure do not recur.
Lee so-and-so, man, 22 years old, people from Guangdong Province, suffered from chronic gastritis more than 3 years, and through western medicine routine treatment, poor effect, come here and go to a doctor, take embodiment 4, serve on 4 doses, after treatment, transference cure does not recur.

Claims (6)

1. treat the compound preparation of superficial gastritis for one kind, it is characterized in that, comprise the raw material of following weight portion: afterbirth 60-90 parts, Semen Raphani 30-60 parts, Rhizoma Corydalis 60-90 parts, Radix Ginseng 30-60 parts, 90-150 parts, Fructus Amomi Rotundus, Herba Pogostemonis 60-90 parts, Bulbus Fritillariae Thunbergii 30-60 parts, the Rhizoma Pinelliae 24-45 parts, Herba Dendrobii 60-90 parts, Rhizoma Alpiniae Officinarum 60-90 parts, Radix Ophiopogonis 60-90 parts, Fructus Gardeniae 60-120 parts, the Radix Aucklandiae 60-90 parts.
2. treat the compound preparation of superficial gastritis according to claim 1, it is characterized in that, comprise the raw material of following weight portion: afterbirth 60-80 parts, Semen Raphani 30-50 parts, Rhizoma Corydalis 60-85 parts, Radix Ginseng 30-50 parts, 90-125 parts, Fructus Amomi Rotundus, Herba Pogostemonis 60-80 parts, Bulbus Fritillariae Thunbergii 30-45 parts, the Rhizoma Pinelliae 30-45 parts, Herba Dendrobii 60-85 parts, Rhizoma Alpiniae Officinarum 60-85 parts, Radix Ophiopogonis 60-85 parts, Fructus Gardeniae 60-100 parts, the Radix Aucklandiae 60-80 parts.
3. the compound preparation for the treatment of superficial gastritis according to claim 1, it is characterized in that, comprise the raw material of following weight portion: afterbirth 75 parts, Semen Raphani 45 parts, Rhizoma Corydalis 75 parts, Radix Ginseng 45 parts, 120 parts, Fructus Amomi Rotundus, Herba Pogostemonis 75 parts, Bulbus Fritillariae Thunbergii 40 parts, the Rhizoma Pinelliae 30 parts, Herba Dendrobii 75 parts, Rhizoma Alpiniae Officinarum 75 parts, Radix Ophiopogonis 75 parts, Fructus Gardeniae 75 parts, the Radix Aucklandiae 75 parts.
4. treat the compound preparation of superficial gastritis according to claim 1, it is characterized in that, comprise the raw material of following weight portion: afterbirth 60 parts, Semen Raphani 30 parts, Rhizoma Corydalis 60 parts, Radix Ginseng 30 parts, 90 parts, Fructus Amomi Rotundus, Herba Pogostemonis 60 parts, Bulbus Fritillariae Thunbergii 30 parts, the Rhizoma Pinelliae 24 parts, Herba Dendrobii 60 parts, Rhizoma Alpiniae Officinarum 60 parts, Radix Ophiopogonis 60 parts, Fructus Gardeniae 60 parts, the Radix Aucklandiae 60 parts.
5. treat the compound preparation of superficial gastritis according to claim 1, it is characterized in that, comprise the raw material of following weight portion: afterbirth 90 parts, Semen Raphani 60 parts, Rhizoma Corydalis 90 parts, Radix Ginseng 60 parts, 150 parts, Fructus Amomi Rotundus, Herba Pogostemonis 90 parts, Bulbus Fritillariae Thunbergii 60 parts, the Rhizoma Pinelliae 45 parts, Herba Dendrobii 90 parts, Rhizoma Alpiniae Officinarum 90 parts, Radix Ophiopogonis 90 parts, Fructus Gardeniae 120 parts, the Radix Aucklandiae 90 parts.
6. treat the compound preparation of superficial gastritis according to claim 1, it is characterized in that, comprise the raw material of following weight portion: afterbirth 80 parts, Semen Raphani 50 parts, Rhizoma Corydalis 85 parts, Radix Ginseng 50 parts, 125 parts, Fructus Amomi Rotundus, Herba Pogostemonis 80 parts, Bulbus Fritillariae Thunbergii 45 parts, the Rhizoma Pinelliae 30 parts, Herba Dendrobii 85 parts, Rhizoma Alpiniae Officinarum 85 parts, Radix Ophiopogonis 85 parts, Fructus Gardeniae 100 parts, the Radix Aucklandiae 80 parts.
CN201510957376.6A 2015-12-17 2015-12-17 Compound preparation for treating superficial gastritis Withdrawn CN105381386A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101244248A (en) * 2008-02-02 2008-08-20 孟德芹 Method of preparing traditional Chinese medicine for treating chronic superficial gastritis
CN103550690A (en) * 2013-10-26 2014-02-05 荣成市科学技术情报研究所 Traditional Chinese medicine composition for treating superficial gastritis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101244248A (en) * 2008-02-02 2008-08-20 孟德芹 Method of preparing traditional Chinese medicine for treating chronic superficial gastritis
CN103550690A (en) * 2013-10-26 2014-02-05 荣成市科学技术情报研究所 Traditional Chinese medicine composition for treating superficial gastritis

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