CN105381095A - 用于治疗由胃热引起的青春痘的药物 - Google Patents

用于治疗由胃热引起的青春痘的药物 Download PDF

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CN105381095A
CN105381095A CN201510995270.5A CN201510995270A CN105381095A CN 105381095 A CN105381095 A CN 105381095A CN 201510995270 A CN201510995270 A CN 201510995270A CN 105381095 A CN105381095 A CN 105381095A
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陈雯雯
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Abstract

本发明公开了一种用于治疗由胃热引起的青春痘的药物，主要由下述重量份配比的原料制成：生地12-18份，丹皮12-18份，蒲公英12-18份，栀子12-18份，枇杷叶8-12份，赤芍12-18份，黄连12-18份，野菊花12-18份，金银花12-18份，板蓝根12-18份，大青叶8-12份，穿心莲12-18份，连翘12-18份，当归12-18份，甘草5-7份。本发明用于治疗由胃热引起的青春痘的药物，选取15种天然中药科学配伍，配方简单，各原料药协同作用起到清热解毒，凉血散瘀的效果，见效快，标本兼治，无毒副作用，而且其制备方法简单、服用方便，成本低。有效率达到95％以上。

Description

用于治疗由胃热引起的青春痘的药物
技术领域
本发明涉及中药，具体是一种用于治疗由胃热引起的青春痘的药物。
背景技术
青春痘，也叫痤疮、粉刺、暗疮，是皮肤科常见病，多发病。主要好发于青少年，在青春期男性有95％，女性有85％患过不同程度的痤疮，所以大家称其为“青春痘”是很贴切的。对青少年的心理和社交影响很大，但青春期后往往能自然减轻或痊愈。青春痘是一种发生于毛囊皮脂腺的慢性皮肤病，多发于头面部，颈部，前胸后背等皮脂腺丰富的部位。痤疮的发生主要与皮脂分泌过多、毛囊皮脂腺导管堵塞、细菌感染和炎症反应等因素密切相关。进入青春期后人体内雄激素特别是睾酮的水平迅速升高，促进皮脂腺发育并产生大量皮脂。同时毛囊皮脂腺导管的角化异常造成导管堵塞，皮脂排出障碍，形成角质栓即微粉刺。毛囊中多种微生物尤其是痤疮丙酸杆菌大量繁殖，痤疮丙酸杆菌产生的脂酶分解皮脂生成游离脂肪酸，同时趋化炎症细胞和介质，最终诱导并加重炎症反应。
皮损好发于面部及上胸背部。痤疮的非炎症性皮损表现为开放性和闭合性粉刺。闭合性粉刺(又称白头)的典型皮损是约1毫米大小的肤色丘疹，无明显毛囊开口。开放性粉刺(又称黑头)表现为圆顶状丘疹伴显著扩张的毛囊开口。粉刺进一步发展会演变成各种炎症性皮损，表现为炎性丘疹、脓疱、结节和囊肿。炎性丘疹呈红色，直径1～5毫米不等；脓疱大小一致，其中充满了白色脓液；结节直径大于5毫米，触之有硬结和疼痛感；囊肿的位置更深，充满了脓液和血液的混合物。这些皮损还可融合形成大的炎性斑块和窦道等。炎症性皮损消退后常常遗留色素沉着、持久性红斑、凹陷性或肥厚性瘢痕。痤疮消退后可留有暂时性色素斑，或小的坑凹状疤痕。
由胃热引起的青春痘多由饮食不节，过食肥甘之物,使肠胃燥结,中焦积热,郁于面部皮肤而致。其症面部丘疹,状如粟米,能挤出白粉样油状物,间有黑头粉刺,以口周为多,亦可见于背部与前胸,且常伴有口干口臭,饮食较多,舌燥,喜冷饮,大便秘结,脉沉实有力等。
现在多以西药治疗为主，但是效果较慢，其副作用大，会引起其他疾病。而目前的一些中药的治疗效率也不甚理想，且疗效不显著。
发明内容
本发明的目的是提供一种疗效好、疗程短、成本低、无毒副作用的治疗由胃热引起的青春痘的药物。
实现本发明目的的技术方案是：
一种用于治疗由胃热引起的青春痘的药物，主要由下述重量份配比的原料制成：
生地12-18份，丹皮12-18份，蒲公英12-18份，栀子12-18份，枇杷叶8-12份，赤芍12-18份，黄连12-18份，野菊花12-18份，金银花12-18份，板蓝根12-18份，大青叶8-12份，穿心莲12-18份，连翘12-18份，当归12-18份，甘草5-7份。
上述用于治疗由胃热引起的青春痘的药物，各原料的最佳重量份配比为：
生地15份，丹皮15份，蒲公英15份，栀子15份，枇杷叶10份，赤芍15份，黄连15份，野菊花15份，金银花15份，板蓝根15份，大青叶10份，穿心莲15份，连翘15份，当归15份，甘草6份。
所述的原料药材在中药店及市场有售。
本发明药物的制备方法如下：按重量配比称取各原料药，加入混合置于容器中，再加原料量重量10-20倍的水煎煮3次，每次煎煮30-40min，合并煎煮液，过滤去渣，滤液浓缩至50-60℃下相对密度为1.20-1.40的浸膏，加入辅料，制成相应的剂型，即得。
本发明中，各原料药的药理、功效如下：
生地：具有清热凉血、益阴生津之功效。用于温热病热入营血，壮热神昏，口干舌绛。
丹皮：清热凉血；活血散瘀。温热病热入血分；发斑；吐衄；热泪盈眶病菌后期热伏阴分发热；阴虚骨蒸潮热；血滞经闭；痛经；痈肿疮毒；跌扑伤痛；风湿热痹。
蒲公英：清热解毒，利尿散结。治急性乳腺炎，淋巴腺炎，瘰疬，疔毒疮肿，急性结膜炎，感冒发热，急性扁桃体炎，急性支气管炎，胃炎，肝炎，胆囊炎，尿路感染。
栀子：泻火除烦，清热利湿，凉血解毒；外用消肿止痛。用于热病心烦，湿热黄疸，淋证涩痛，血热吐衄，目赤肿痛，火毒疮疡，外治扭挫伤痛。
枇杷叶：清肺止咳，降逆止呕。肺热咳嗽，气逆喘急，胃热呕吐，哕逆。可治疗口干消渴，肺风面疮，粉刺。
赤芍：清热凉血，散瘀止痛。用于热人营血，温毒发斑，吐血衄血，目赤肿痛，肝郁胁痛，经闭痛经，瘾瘕腹痛，跌扑损伤，痈肿疮疡。
黄连：清热燥湿，泻火解毒。湿热痞满，呕吐吞酸，泻痢，黄疸，高热神昏，心火亢盛，心烦不寐，心悸不宁，血热吐衄，目赤，牙痛，消渴，痈肿疗疮；外治湿疹，湿疮，耳道流脓。
野菊花：具疏散风热、消肿解毒。能治疗疔疮痈肿、咽喉肿痛、风火赤眼、头痛眩晕等病证。
金银花：既能宣散风热，还善清解血毒，用于各种热性病，如身热、发疹、发斑、热毒疮痈、咽喉肿痛等症。
板蓝根：清热解毒、凉血消斑，治温病发热、发斑、风热感冒、咽喉肿痛、丹毒、流行性乙型脑炎、肝炎和腮腺炎等症。
大青叶：清热解毒，凉血消斑。用于热病高热烦渴；神昏；斑疹；吐血；衄血；黄疸；泻痢；丹毒；喉痹；口疮；痄腮。
穿心莲：有清热解毒、消炎、消肿止痛作用。常用于感冒发热，咽喉肿痛，口舌生疮，顿咳劳嗽，泄泻痢疾，热淋涩痛，痈肿疮疡，蛇虫咬伤。
连翘：清热，解毒，散结，消肿。治温热，丹毒，斑疹，痈疡肿毒，瘰疬，小便淋闭。
当归：具有补血活血，调经止痛，润肠通便之功效。常用于血虚萎黄，眩晕心悸，月经不调，经闭痛经，虚寒腹痛，风湿痹痛，跌扑损伤，痈疽疮疡，肠燥便秘。
甘草：具有补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药之功效。常用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
本发明用于治疗由胃热引起的青春痘的药物，选取15种天然中药科学配伍，配方简单，各原料药协同作用起到清热解毒，凉血散瘀的效果，见效快，标本兼治，无毒副作用，而且其制备方法简单、服用方便，成本低。
具体实施方式
下面结合实施例对本发明内容作进一步的说明，但不是对本发明的限定。
实施例1
一种用于治疗由胃热引起的青春痘的药物，主要由下述重量份配比的原料制成：
生地12kg，丹皮12kg，蒲公英12kg，栀子12kg，枇杷叶8kg，赤芍12kg，黄连12kg，野菊花12kg，金银花12kg，板蓝根12kg，大青叶8kg，穿心莲12kg，连翘12kg，当归12kg，甘草5kg。
制备方法如下：按上述称取各原料药混合置于容器中，再加原料量重量10倍的水煎煮3次，每次煎煮30min，合并煎煮液，过滤去渣，滤液浓缩至50℃下相对密度为1.20的浸膏，加入辅料，制成片剂，每片0.1g。
实施例2
一种用于治疗由胃热引起的青春痘的药物，主要由下述重量份配比的原料制成：
生地15kg，丹皮15kg，蒲公英15kg，栀子15kg，枇杷叶10kg，赤芍15kg，黄连15kg，野菊花15kg，金银花15kg，板蓝根15kg，大青叶10kg，穿心莲15kg，连翘15kg，当归15kg，甘草6kg。
制备方法如下：按上述称取各原料药混合置于容器中，再加原料量重量15倍的水煎煮3次，每次煎煮34min，合并煎煮液，过滤去渣，滤液浓缩至53℃下相对密度为1.30的浸膏，加入辅料，制成片剂，每片0.2g。
实施例3
一种用于治疗由胃热引起的青春痘的药物，主要由下述重量份配比的原料制成：
生地18kg，丹皮18kg，蒲公英18kg，栀子18kg，枇杷叶12kg，赤芍18kg，黄连18kg，野菊花18kg，金银花18kg，板蓝根18kg，大青叶12kg，穿心莲18kg，连翘18kg，当归18kg，甘草7kg。
制备方法如下：按上述称取各原料药混合置于容器中，再加原料量重量18倍的水煎煮3次，每次煎煮37min，合并煎煮液，过滤去渣，滤液浓缩至57℃下相对密度为1.30的浸膏，加入辅料，制成丸剂，每粒0.4g。
实施例4
一种用于治疗由胃热引起的青春痘的药物，主要由下述重量份配比的原料制成：
生地18kg，丹皮18kg，蒲公英18kg，栀子18kg，枇杷叶12kg，赤芍18kg，黄连18kg，野菊花18kg，金银花18kg，板蓝根18kg，大青叶12kg，穿心莲18kg，连翘18kg，当归18kg，甘草7kg。
制备方法如下：按上述称取各原料药混合置于容器中，再加原料量重量20倍的水煎煮3次，每次煎煮40min，合并煎煮液，过滤去渣，滤液浓缩至60℃下相对密度为1.40的浸膏，加入辅料，制成丸剂，每粒0.5g。
为了进一步证明本发明中药的临床疗效，选择收治患者中的200例，对本发明药物的疗效进行临床观察。年龄15-35岁，随机分为4组，每组为50例，分别为实验组1-4组。
实验组1-4组分别服用实施例1-4的药物，每日2次，每次内服3片/粒，10天为一个疗程，连续服用2-3个疗程，视病情轻重加减疗程。其中显效185例，有效182例，治愈190例，无效10例，治愈率91％，有效率95％。

Claims (3)

1.一种用于治疗由胃热引起的青春痘的药物，其特征是：主要由下述重量份配比的原料制成：
生地12-18份，丹皮12-18份，蒲公英12-18份，栀子12-18份，枇杷叶8-12份，赤芍12-18份，黄连12-18份，野菊花12-18份，金银花12-18份，板蓝根12-18份，大青叶8-12份，穿心莲12-18份，连翘12-18份，当归12-18份，甘草5-7份。
2.根据权利要求1所述的用于治疗由胃热引起的青春痘的药物，其特征是：各原料的最佳重量份配比为：
生地15份，丹皮15份，蒲公英15份，栀子15份，枇杷叶10份，赤芍15份，黄连15份，野菊花15份，金银花15份，板蓝根15份，大青叶10份，穿心莲15份，连翘15份，当归15份，甘草6份。
3.根据权利要求1所述的用于治疗由胃热引起的青春痘的药物，其特征是：
制备方法如下：按重量配比称取各原料药，加入混合置于容器中，再加原料量重量10-20倍的水煎煮3次，每次煎煮30-40min，合并煎煮液，过滤去渣，滤液浓缩至50-60℃下相对密度为1.20-1.40的浸膏，加入辅料，制成相应的剂型，即得。
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CN105998902A (zh) * 2016-06-30 2016-10-12 江苏秀宇生物医药科技有限公司 治疗青春痘的中药组合物
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