CN105380712A - Guiding stent based on 3D printing and used for cerebral hemorrhage minimally invasive surgery and preparation method thereof - Google Patents
Guiding stent based on 3D printing and used for cerebral hemorrhage minimally invasive surgery and preparation method thereof Download PDFInfo
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- CN105380712A CN105380712A CN201510703437.6A CN201510703437A CN105380712A CN 105380712 A CN105380712 A CN 105380712A CN 201510703437 A CN201510703437 A CN 201510703437A CN 105380712 A CN105380712 A CN 105380712A
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Abstract
The invention discloses a guiding stent which is obtained by the adoption of 3D printing technology and used for cerebral hemorrhage minimally invasive surgery and preparation method thereof. The preparation method comprises the steps of firstly, scanning the head of a hemorrhage patient so that head image file data can be obtained, then sorting the skull facial profile and target hematoma in need of removal, establishing a three-dimensional model which is closely attached to the skull face of the patient relative to the immobile area profile, designing a hollow non-closed-loop puncture guiding channel stent model in the model, adjusting the direction of a puncture channel, the size of a base and length post-output files of the non-closed-loop puncture channel, conducting 3D printing, and obtaining the accurate guiding stent used for cerebral hemorrhage minimally invasive surgery of the patient. The guiding stent has the advantages that customization of individual characters is achieved, positioning is accurate, infection is avoided, the wound is small, the process is simple, and cost is low.
Description
Technical field
The present invention relates to and prepare cerebral hemorrhage operation apparatus, particularly a kind of cerebral hemorrhage minimum traumatic operation guide support based on 3D printing and preparation method thereof.
Background technology
Cerebral hemorrhage has the higher fatality rate that disables.The healing of cerebral hemorrhage and bleeding part, amount of bleeding and rescue time closely related, cerebral hemorrhage position often occurs in intracranial important core group distributed areas, and the bones of limbs tissue of these regions and periphery, craniofacial region muscular tissue and digestive viscera are organized completely different, they not only have important nerve fibre bundle to pass, there is the close net blood vessel group of domination functional areas to pass by simultaneously, operating difficulty is very big, to operation precisely require high.
Along with the development of minimally invasive technique, cone cranium hematoma puncture is applied more and more on cerebral hemorrhage treatment in conjunction with urokinase drainage, this therapy has the advantages such as simple and easy to do, safe, reliable, economic, practical, effective, but the error of preoperative CT location, the experience difference of operator in art, individual patient difference all can cause puncture distance, direction etc. to occur deviation, causes puncture failure, based on this, how more accurately operation is carried out in location is very important.In current art, CT location, computer assisted navigation, operating robot such as to assist be location of operation system more common clinically at the aided positioning system, wherein in art CT to be positioned at most hospital more universal, equipment price is cheap, but malfunction in art, and have x radiation x; Although computer assisted navigation registration, real-time image support in art, can be provided, expensive, need mounting and positioning device; Operating robot is up-to-date Intraoperative position means, which overcome hand tremor registration, but price is extremely expensive, more difficult universal.
Craniofacial region is that the mankind change one of maximum organic region, the model that any " standard " is changed all is difficult to perfect laminating, simultaneously because facial expression myokinesis usually causes craniofacial region appearance inconsistent because the time is different, these features and osseous tissue completely different, the personalized model customization of constructing applicable patient's craniofacial region feature is caused to bother very much, and 3D printing technique is one of the most popular current forming materials research direction, it is assisting by image technology data, appliance computer aided design techniques fictionalizes the three dimensional structure of body to be built, then corresponding material is utilized, a kind of organizational project successively creating out entity learns a skill.Thus data is learned by obtaining patient image, by selecting relative " fixed point " of patient's craniofacial region projection, if the positions such as volume, glabella, eye socket, nose, external auditory meatus, outer canthus or mastoid process are as target area, cerebral hemorrhage minimum traumatic rack for operation navigation system precisely can be guided by making in conjunction with 3D printing technique, there is high accuracy, structure speed is fast, the advantage such as can realize manufacturing as required because of advantages such as personalization, precision, long-ranges, be particularly suitable for the application of medical domain.
Summary of the invention
The present invention is directed to prior art deficiency, costly or poor accuracy problem, propose a kind of cerebral hemorrhage minimum traumatic operation guide support printed based on 3D, with and preparation method thereof.
The technical scheme that the present invention is complete comprises:
A kind of cerebral hemorrhage minimum traumatic operation guide support, comprise the hollow non-closed loop guided puncture passage of base and end sensing target hematoma, it is characterized in that, described base is closely in conjunction with patient's craniofacial region profile.
The position that described base and patient's craniofacial region are fitted closely comprises: one or more in volume, glabella, eye socket, nose, external auditory meatus, outer canthus or mastoid process.
Described base thickness is about 2-3mm, and area is 20cm
2-60cm
2.
Described hollow non-closed loop guided puncture passage length is about 3-4cm, and diameter is 6mm.
Described puncture channel avoids sinus frontalis, gas room, intracranial common blood vessel traveling position and functional areas, and passage points to target hematoma center.
The application of above-described cerebral hemorrhage minimum traumatic operation guide support in cerebral hemorrhage minimum traumatic operation.
The preparation method of above-described cerebral hemorrhage minimum traumatic operation guide support, is characterized in that, comprise the steps:
Step one, utilize image documentation equipment to patients with cerebral hemorrhage head through row thin slice scan, obtain patient's head image file data;
Step 2, by 3D reverse engineering software, obtained data to be processed, sub-elect patient's craniofacial region profile and need the target hematoma removed;
Step 3, utilize 3D design software to build the threedimensional model of the closely relatively motionless region contour of laminating patient's craniofacial region, model designs hollow non-closed loop guided puncture channel bracket model;
Step 4, adjust this puncture channel direction, avoid sinus frontalis, gas room, intracranial common blood vessel traveling position and functional areas, passage points to target hematoma center,
Step 5, adjustment cover the base size of craniofacial region model and non-closed loop guided puncture passage length, output file closely.
Step 6, the file importing 3D printer that will export, obtain the operation of this patient's cerebral hemorrhage minimum traumatic and use accurate guide support.
Described image documentation equipment is CT or MRI, and described patient's head image file data format is DICOM.
The reverse engineering software of 3D described in step 2 is mimics software, and 3D design software described in step 3 to step 5 is 3-matic software, and described file is STL form.
In described step 6, the raw material printed as 3D with polylactic acid or acrylonitrile-butadiene-styrene copolymer.
The present invention is relative to the advantage of prior art:
1. accurate: the personalized cerebral hemorrhage operation built by the method for the present invention three-dimensional data that accurate guide support is rebuild according to patient's head scanning completely designs, the base of support and the perfection of patient's craniofacial region are fitted, the change of the profile brought is shunk for overcoming patient's craniofacial region histrionic muscles, we manually select the relative fixed point of craniofacial region as fit area, and build base with this region; And the guiding device end direction of one points to target hematoma center, enter with this access penetrations pipe hematoma of going directly.
2. safety: by the puncture channel of this support, drainage tube enters hematoma of going directly, avoid inserting sinus frontalis, gas room, intracranial common blood vessel traveling position and functional areas, at utmost reduce the injury of puncture, simultaneously this support is that brain is fitted outward support, can not intracranial be entered, can effectively avoid intracranial infection and material contamination.
3. efficient: to go directly hematoma with the personalized cerebral hemorrhage operation guide support section that method of the present invention builds, hematoma need not be located by methods such as traditional triangulation body surface location, thus reach shortening operating time, alleviate in operation in patients painful; Meanwhile, adopt guide support of the present invention, operative incision only needs about 6mm size, is conducive to patient's prognosis.
4. simple to operate: research method of the present invention removes loaded down with trivial details computing formula, by stereo-picture straightforward manipulation, need not convert, be convenient to left-hand seat.
5. low cost: the region that the method for the present invention's research prints is the laminating relative fixed point region of craniofacial region, local, by printing objects size reduction at 20cm
2to 60cm
2in, thickness is about 2-3mm, and non-closed loop guided puncture passage length is about 3-4cm, and diameter is 6mm, shortens the time-write interval, saves printed material consumption.
Accompanying drawing explanation
Fig. 1 is the front elevation of the accurate guide support of personalized cerebral hemorrhage operation of the present invention;
Fig. 2 is the side view of the accurate guide support of personalized cerebral hemorrhage operation of the present invention;
Fig. 3 is the schematic perspective view of the accurate guide support of personalized cerebral hemorrhage operation of the present invention;
Fig. 4 is that the accurate guide support of personalized cerebral hemorrhage operation of the present invention uses schematic diagram.
In figure: 1, hollow non-closed loop guided puncture passage; The base of 2, fitting with face, nose; 3, patient's craniofacial region; 4, target hematoma.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention will be further described.
Embodiment 1 one kinds utilizes 3D printing technique to prepare personalized cerebral hemorrhage operation accurate guide support and method thereof, and concrete grammar is as follows:
1) utilize CT to patients with cerebral hemorrhage head through row thin slice scan, obtain the DICOM formatted data file that this patient comprises three-dimensional information data.
2) the Dicom format picture data of acquisition is stored in CD or DVD CD, import to Mimics17.0 medical operation design software (Materialise company, Belgium) in, import data procedures and select atraumatic fashion, at working interface, 3-D view modeling is carried out to operation area surface portion (geisoma, glabella, nose, nasolabial fold, outer canthus, on socket of the eye) and hematoma.
3) 3-dimensional image model created is copied in 3-Matic9.0 (Materialise company, Belgium) software, carry out craniofacial region and hematoma structural analysis, the design of design entry point and hollow non-closed loop guided puncture passage.
4) adjust this puncture channel direction in 3-Matic software, should avoid sinus frontalis, gas room, intracranial common blood vessel traveling position and functional areas, passage points to target hematoma center, and measures the virtual puncture path length arriving hematoma center.
5) utilize the function adjustment of wiping out of 3-Matic software closely to cover craniofacial region model base size and hollow non-closed loop guided puncture passage length, export as STL form.
6) STL formatted file being imported printer Slice Software, take polylactic acid as raw material, obtains the operation of this patient's cerebral hemorrhage minimum traumatic and uses accurate guide support.
During operation, guide support the inventive method obtained is inserted in sterile plastic sheet, patient gets dorsal position, after normal sterile sterilization, the forehead point of puncture getting support location cuts the otch being about 6mm, electric drill becomes a 5mm hole in skull, base 2 perfection is made by this guide support to fit in patient's craniofacial region 3, assistant's fixed support, operator is held hematoma drainage tube and is penetrated along hollow non-closed loop guided puncture passage 1 center, and the degree of depth measures gained by step 4, target approach hematoma 4, extract puncture tube core, fixing puncture tube connects drainage system, performs the operation complete.
Many-side involved in the present invention has been done and has as above been set forth.It is to be understood, however, that put before not departing from spirit of the present invention, those skilled in the art carry out equivalent change and modification to it, and described change and modification fall into the coverage of the application's claims equally.
Claims (10)
1. a cerebral hemorrhage minimum traumatic operation guide support, comprise the hollow non-closed loop guided puncture passage of base and end sensing target hematoma, it is characterized in that, described base is closely in conjunction with patient's craniofacial region profile, and the method that described support adopts 3D to print obtains.
2. support according to claim 1, is characterized in that, the position that described base and patient's craniofacial region are fitted closely comprises: one or more in volume, glabella, eye socket, nose, external auditory meatus, outer canthus or mastoid process.
3. the support described in claim 1 or 2, is characterized in that, described base thickness is about 2-3mm, and area is 20cm
2-60cm
2.
4. the support described in claim 1-3, is characterized in that, described non-closed loop guided puncture passage length is about 3-4cm, and diameter is 6mm.
5. support according to claim 1, is characterized in that, described non-closed loop guided puncture passage avoids sinus frontalis, gas room, intracranial common blood vessel traveling position and functional areas, and passage points to target hematoma center.
6. the application of the cerebral hemorrhage minimum traumatic operation guide support described in any one of claim 1-5 in cerebral hemorrhage minimum traumatic operation.
7. the preparation method of the cerebral hemorrhage minimum traumatic operation guide support described in any one of claim 1-5, is characterized in that, comprise the steps:
Step one, utilize image documentation equipment to patients with cerebral hemorrhage head through row thin slice scan, obtain patient's head image file data;
Step 2, by 3D reverse engineering software, obtained data to be processed, sub-elect patient's craniofacial region profile and need the target hematoma removed;
Step 3, utilize 3D design software to build the threedimensional model of the closely relatively motionless region contour of laminating patient's craniofacial region, model designs hollow non-closed loop guided puncture channel bracket model;
Step 4, adjust this non-closed loop guided puncture channel direction, avoid sinus frontalis, gas room, intracranial common blood vessel traveling position and functional areas, passage points to target hematoma center,
Step 5, adjustment cover the base size of craniofacial region model and non-closed loop guided puncture passage length, output file closely.
Step 6, the file importing 3D printer that will export, obtain the operation of this patient's cerebral hemorrhage minimum traumatic and use accurate guide support.
8. method according to claim 7, is characterized in that, described image documentation equipment is CT or MRI, and described patient's head image file data format is DICOM.
9. method according to claim 7, is characterized in that, the reverse engineering software of 3D described in step 2 is mimics software, and 3D design software described in step 3 to step 5 is 3-matic software, and described file is STL form.
10. method according to claim 7, is characterized in that, in described step 6, and the raw material printed as 3D with polylactic acid or acrylonitrile-butadiene-styrene copolymer.
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Cited By (9)
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CN105496568A (en) * | 2016-01-14 | 2016-04-20 | 吴祥 | Auxiliary guide device used for accurately puncturing deep tissue of head and face and puncturing method |
CN106618672A (en) * | 2016-11-11 | 2017-05-10 | 广西中医药大学附属瑞康医院 | Guide plate and manufacturing equipment thereof |
CN108986622A (en) * | 2018-08-16 | 2018-12-11 | 广州迈普再生医学科技股份有限公司 | A kind of intracranial hematoma microtrauma puncture removes art training device and preparation method thereof |
CN109199551A (en) * | 2018-10-15 | 2019-01-15 | 赵华 | Stereotaxic technique between individuation Naokong |
CN109646087A (en) * | 2018-12-10 | 2019-04-19 | 湘潭市第人民医院 | A kind of puncture supporter and production method of Patients With Cerebral Hemorrhage Accepted Micro-traumatic Treatment |
CN109893223A (en) * | 2019-02-28 | 2019-06-18 | 成都真实维度科技有限公司 | A kind of 3D printing cerebral hemorrhage puncture drainage path orientation device and preparation method thereof |
CN110664482A (en) * | 2019-10-08 | 2020-01-10 | 陈骏 | Method for preparing head digital model and multi-stage guide plate based on three-dimensional reconstruction technology |
CN110840533A (en) * | 2019-11-30 | 2020-02-28 | 青岛市城阳区人民医院 | 3D-printed guide support for cerebral hemorrhage minimally invasive surgery and preparation method thereof |
CN111887958A (en) * | 2020-08-26 | 2020-11-06 | 杭州市第一人民医院 | Adjustable cerebral hemorrhage minimally invasive surgery positioning device |
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CN105496568A (en) * | 2016-01-14 | 2016-04-20 | 吴祥 | Auxiliary guide device used for accurately puncturing deep tissue of head and face and puncturing method |
CN106618672A (en) * | 2016-11-11 | 2017-05-10 | 广西中医药大学附属瑞康医院 | Guide plate and manufacturing equipment thereof |
CN108986622A (en) * | 2018-08-16 | 2018-12-11 | 广州迈普再生医学科技股份有限公司 | A kind of intracranial hematoma microtrauma puncture removes art training device and preparation method thereof |
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CN109646087A (en) * | 2018-12-10 | 2019-04-19 | 湘潭市第人民医院 | A kind of puncture supporter and production method of Patients With Cerebral Hemorrhage Accepted Micro-traumatic Treatment |
CN109893223A (en) * | 2019-02-28 | 2019-06-18 | 成都真实维度科技有限公司 | A kind of 3D printing cerebral hemorrhage puncture drainage path orientation device and preparation method thereof |
CN110664482A (en) * | 2019-10-08 | 2020-01-10 | 陈骏 | Method for preparing head digital model and multi-stage guide plate based on three-dimensional reconstruction technology |
CN110840533A (en) * | 2019-11-30 | 2020-02-28 | 青岛市城阳区人民医院 | 3D-printed guide support for cerebral hemorrhage minimally invasive surgery and preparation method thereof |
CN111887958A (en) * | 2020-08-26 | 2020-11-06 | 杭州市第一人民医院 | Adjustable cerebral hemorrhage minimally invasive surgery positioning device |
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