CN103750923A - Artificial temporal-mandibular joint based on selective laser melting technology and manufacturing method thereof - Google Patents

Artificial temporal-mandibular joint based on selective laser melting technology and manufacturing method thereof Download PDF

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Publication number
CN103750923A
CN103750923A CN201310712553.5A CN201310712553A CN103750923A CN 103750923 A CN103750923 A CN 103750923A CN 201310712553 A CN201310712553 A CN 201310712553A CN 103750923 A CN103750923 A CN 103750923A
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Prior art keywords
remporomandibular joint
condyle
artificial
selective laser
laser melting
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张志光
陈建宇
罗崇岱
张春雨
陈贤帅
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ORAL SUBSIDIARY SUN YAT-SEN UNIVERSITY HOSPITAL
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ORAL SUBSIDIARY SUN YAT-SEN UNIVERSITY HOSPITAL
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Priority to CN201310712553.5A priority Critical patent/CN103750923A/en
Publication of CN103750923A publication Critical patent/CN103750923A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30988Other joints not covered by any of the groups A61F2/32 - A61F2/4425
    • A61F2/3099Other joints not covered by any of the groups A61F2/32 - A61F2/4425 for temporo-mandibular [TM, TMJ] joints
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof

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  • Health & Medical Sciences (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

The invention discloses an artificial temporal-mandibular joint based on selective laser melting technology and a manufacturing method thereof. The artificial temporal-mandibular joint comprises a condyle process, a condylar neck and a titanium plate formed with nail holes; the same as the structure of the mandible of human body, the condyle process is protruded at the rear edge of the upper end of the condylar neck; the titanium plate is mounted at the lower end of the condylar neck. According to the artificial temporal-mandibular joint based on selective laser melting technology and the manufacturing method thereof, the artificial temporal-mandibular joint is printed and formed in three dimensional mode through using selective laser melting technology, and the artificial temporal-mandibular joint is made according to the mandible shape of each patient, and accordingly the artificial temporal-mandibular joint is perfectly matched with the mandible structure of the patient.

Description

Based on artificial remporomandibular joint and the manufacture method thereof of selective laser melting technology
Technical field
The present invention relates to artificial joint field, specifically a kind of artificial remporomandibular joint and manufacture method thereof based on selective laser melting technology.
Background technology
Remporomandibular joint (TMJ) is the interlock joint, left and right that jaw face has rotation and sliding motion.Tumor, wound or fracture, congenital malformation and osteochondritis can cause remporomandibular joint occupying lesion or ankylosis, have a strong impact on chew, swallow, the critical function such as language, and the reasons such as tumor resection, bony ankylosis of TMJ operation and major injury can cause condyle of mandible disappearance.For 1/3 height and remporomandibular joint function under recovery face, need row reconstruction of Temporomandibular Joint.Reconstruction of Temporomandibular Joint is to utilize autograft or artificial joint prosthesis to implant, and rebuilds the articulation structure that approaches physiological status, recovers profile and the function of condyle of mandible, alleviates patient's pain, prevents further developing of joint disease.
Of the prior art, artificial remporomandibular joint is generally used finished product artificial joint, and its articular morphology is single, for the titanium plate of planar band screw hole adds the semicircle imitative condyle lug structure in upper end.This structure does not meet the prominent anatomic form of nature condyle, can not realize the prominent slip of condyle and rotate the functional exercise of combination; In addition, the finished product that the prominent prosthese of most condyles is batch production, size design is difficult to meet each patient's needs.
Being not difficult to find out, also there is certain defect in prior art.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of artificial remporomandibular joint and manufacture method thereof based on selective laser melting technology, adopt selective laser melting technology to carry out 3D printing shaping to artificial remporomandibular joint, artificial remporomandibular joint is customized according to each patient's lower jaw shape, high with patient's lower jaw structure degree of agreement.
Based on an artificial remporomandibular joint for selective laser melting technology, comprising: condyle is prominent, neck of condyle portion and be provided with the titanium plate in nail hole; Condyle thumping arises from the trailing edge of neck of condyle portion upper end; Described titanium plate is arranged at neck of condyle subordinate end.
Further, the described artificial remporomandibular joint based on selective laser melting technology also comprises processus coracoideus; Described processus coracoideus is projected on the leading edge of neck of condyle portion upper end.
Further, described condyle is prominent, neck of condyle portion and processus coracoideus, respectively equal and opposite in direction, the form symmetry of, neck of condyle portion prominent with the condyle of the strong side of patient's lower jaw and processus coracoideus.
Further, the nail hole number on described titanium plate is no less than 2.
A manufacture method for artificial remporomandibular joint based on selective laser melting technology, comprises the following steps:
S1, scanning, obtain the temporomandibular basic three-dimensional profile data of patient by CT scan;
S2, modeling, basic three-dimensional profile data are processed, according to operation osteotomy situation, by strong side block that more than plane condyle is prominent, neck of condyle portion and beak lug structure do sagittal plane upset, and add in the cheek side of upset condyle cervical region lower end the titanium plate fitting like a glove with mandible surface, to set up the three dimensional computer modeling of described artificial remporomandibular joint;
S3, connection design, connect design to the three dimensional computer modeling of described artificial remporomandibular joint;
S4, generating process parameter, carry out layering processing to the three dimensional computer modeling of described artificial remporomandibular joint, generates corresponding scanning pattern, preserves and derive corresponding technological parameter;
S5,3D print, and described technological parameter is imported to 3D printing device, carry out 3D printing;
S6, sandblast, print to 3D the semi-finished product that make and carry out blasting treatment.
Further, described step S5 specifically comprises the following steps:
S501, described 3D printing device are provided with substrate, titanium valve layer on uniform spreading on substrate;
S502, utilize superlaser by the titanium valve layer on scanning pattern scanning substrate, make that titanium valve melting layer is cooling to be cemented on substrate;
S503, on fixed titanium valve layer, repave new titanium valve layer, and by scanning pattern, new titanium valve layer is carried out to laser scanning;
S504, repeating step S503, until the artificial complete molding of remporomandibular joint, the more artificial remporomandibular joint of molding is taken out from substrate.
Further, described technological parameter comprises scan mode, scanning speed, power and the spot diameter of putting position, disposing way and the laser of artificial remporomandibular joint workpiece.
Further, the power of described laser is 50-200W, and the spot diameter of laser is 50-180 μ m, and the scanning speed of laser is 50-500mm/s.
Further, the thickness of described titanium valve layer is 10-80 μ m; Described titanium valve layer is comprised of the pure titanium powder of spherical particle, and the pure titanium powder diameter of spherical particle is 10-100 μ m.
Further, described step S501 is to step S504, and artificial remporomandibular joint workpiece all carries out processing and forming in the argon shield environment of 99.999wt.%.
A kind of artificial remporomandibular joint and manufacture method thereof based on selective laser melting technology provided by the present invention, adopt selective laser melting technology to carry out 3D printing shaping to artificial remporomandibular joint, manufacture flexible degree is high, artificial remporomandibular joint can, according to patient's lower jaw structure personalized customization, have the high goodness of fit with patient's lower jaw structure.
Accompanying drawing explanation
In order to be illustrated more clearly in the embodiment of the present invention or technical scheme of the prior art, to the accompanying drawing of required use in embodiment or description of the Prior Art be briefly described below, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skills, do not paying under the prerequisite of creative work, can also obtain according to these accompanying drawings other accompanying drawing.
The structural representation of a kind of artificial remporomandibular joint based on selective laser melting technology that Fig. 1 provides for the embodiment of the present invention.
Description of reference numerals:
1, prominent 2, the neck of condyle portion of condyle
3, processus coracoideus 4, titanium plate
5, nail hole
The specific embodiment
For making object, technical scheme and the advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention and accompanying drawing, the technical scheme in the embodiment of the present invention is clearly and completely described.It should be noted that, described embodiment is only the present invention's part embodiment, rather than whole embodiment.Based on the embodiment in the present invention, those of ordinary skills, not making the every other embodiment obtaining under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment
Refer to Fig. 1, the invention provides a kind of artificial remporomandibular joint based on selective laser melting technology, comprising: condyle is prominent 1, neck of condyle portion 2 and be provided with the titanium plate 4 in nail hole 5; With human body lower jaw structure in the same manner, condyle prominent 1 is projected on the trailing edge of neck of condyle portion 2 upper ends; Neck of condyle portion 2 lower ends are provided with titanium plate 4.
The described artificial remporomandibular joint based on selective laser melting technology also comprises processus coracoideus 3; With human body lower jaw structure in the same manner, processus coracoideus 3 is projected on the leading edge of neck of condyle portion 2 upper ends.
Artificial structure of temporomandibular articulation of the present invention, identical with human body lower jaw structure.The structure that described condyle is prominent 1, neck of condyle portion 2 and processus coracoideus 3 are human body lower jaw.It should be noted that, according to mechanics study, show, processus coracoideus 3 does not play main stressed effect in mandibular joint, for making more lightweight of artificial remporomandibular joint of the present invention, can, under the judgement of doctor or person skilled, omit processus coracoideus 3 structures.In reconstruction of Temporomandibular Joint, described titanium plate 4 is followed closely with the mandibular ramus of human body and is rigidly connected by titanium, makes the artificial remporomandibular joint of the present invention replace impaired mandibular condyle 1 joint of patient.
Described condyle is prominent 1, neck of condyle portion 2 and processus coracoideus 3, respectively equal and opposite in direction, the form symmetry of, neck of condyle portion 2 prominent 1 with the condyle of the strong side of patient's lower jaw and processus coracoideus 3.
Unlike the prior art, the mandible prosthesis finished product that artificial remporomandibular joint of the present invention is not produced in batches by single specification, but by personalized customized the forming of patient's lower jaw structure.The condyle of artificial remporomandibular joint of the present invention is prominent 1, neck of condyle portion 2 and processus coracoideus 3, and completely prominent 1 according to the condyle of the strong side of patient's lower jaw, neck of condyle portion 2 and processus coracoideus 3 are by one to one symmetrical obtained by molding, and its structure and patient's physiological structure is in full accord.
Nail hole 5 quantity on described titanium plate 4 are no less than two.
If the quantity in nail hole 5 only has one, can cause artificial remporomandibular joint of the present invention to be connected with patient's mandibular ramus cannot be fully fixing, make artificial remporomandibular joint only hinged with patient's mandibular ramus, artificial remporomandibular joint still can be rotated in patient's mandibular ramus.For guaranteeing to connect closely, fully fixing, nail hole 5 quantity on titanium plate 4 are no less than two.
The present invention also provides a kind of manufacture method of the artificial remporomandibular joint based on selective laser melting technology, comprises the following steps:
S1, scanning, obtain the temporomandibular basic three-dimensional profile data of patient by CT scan;
This step is directly obtained three-dimensional profile data from patient's lower jaw by CT scan, is one of important step being different from prior art.Prior art only copies the profile of human body lower jaw to do corresponding design, and batch making goes out the mandible prosthesis of several different models.Apparently, each patient's lower jaw planform has individual variation, obviously can not coincide each patient's physiological structure of the finished product prosthese of Batch Design.
S2, modeling, basic three-dimensional profile data are processed, according to operation osteotomy situation, by strong side block that more than plane condyle is prominent 1, neck of condyle portion 2 and processus coracoideus 3 structures do sagittal plane upset, and add in the cheek side of upset condyle cervical region 2 lower ends the titanium plate 4 fitting like a glove with mandible surface, to set up the three dimensional computer modeling of described artificial remporomandibular joint;
This step is the subsequent treatment of step S1.The three-dimensional profile data that obtain from patient by step S1, data are carried out to three-dimensional modeling, and can be in three dimensional computer modeling prominent 1 according to the condyle of the strong side of patient, neck of condyle portion 2 and processus coracoideus 3 structures, reconstruct replaces that condyle in damaged condition is prominent 1, neck of condyle portion 2 and processus coracoideus 3 structures, guarantees that repair structure and patient's physiological structure fits like a glove.
S3, connection design, connect design to the three dimensional computer modeling of described artificial remporomandibular joint;
Owing to only needing in reconstruction of Temporomandibular Joint, condyle to damaging is prominent 1, neck of condyle portion 2 and processus coracoideus 3 structures are rebuild, therefore only need to produce have that condyle is prominent 1, the artificial remporomandibular joint of neck of condyle portion 2 and processus coracoideus 3 structures, more artificial remporomandibular joint is connected with human body mandibular ramus.Artificial remporomandibular joint connected with being connected by titanium plate 4 of human body mandibular ramus.Therefore, should be according to patient's concrete condition, design corresponding titanium plate 4, and design required nail hole 5, for connecting artificial remporomandibular joint and human body mandibular ramus, guarantee that artificial remporomandibular joint is tight with being connected of human body mandibular ramus, fully fixing.Can utilize if desired quantity and the intensity in the method validation nail hole 5 of finite element analysis whether to meet the demands.
S4, generating process parameter, carry out layering processing to the three dimensional computer modeling of described artificial remporomandibular joint, generates corresponding scanning pattern, preserves and derive corresponding technological parameter;
This step is the pretreatment to step S5.Will carry out entity shaping manufacture to the three dimensional computer modeling of above-mentioned steps modeling gained, must carry out data transaction to three dimensional computer modeling, generate corresponding technological parameter, for step, S5 prepares.Described technological parameter comprises scan mode, scanning speed, power and the spot diameter of putting position, disposing way and the laser of artificial remporomandibular joint workpiece.
S5,3D print, and described technological parameter is imported to 3D printing device, carry out 3D printing;
This step is the another step that is different from prior art.Utilize selective laser melting technology to carry out 3D printing shaping, there is high processing flexibility.The technological parameter generating according to step S4, directly completes the molding manufacture of artificial remporomandibular joint, and production efficiency is high, manufactures can coincide different patients' personalized physiological structure of finished product.
S6, sandblast, print to 3D the semi-finished product that make and carry out blasting treatment.
This step is for carrying out polish to the semi-finished product of step S5 gained.The accidental aperture, pure titanium metal surface of step S5 gained is about the irregular hole of 30 μ m.The pure titanium semi-finished product of laser formation, after step S6 blasting treatment, can be removed the not sintering spherical particle completely of metal surface, and can reduce surperficial roughness.Our experiments show that, artificial remporomandibular joint surface roughness is 12.4 μ m before sandblast, is 2.3 μ m after sandblast, and the artificial remporomandibular joint surface after sandblast is obviously than more smooth before sandblast.
Described step S5 specifically comprises the following steps:
S501, described 3D printing device are provided with substrate, titanium valve layer on uniform spreading on substrate;
S502, utilize superlaser by the titanium valve layer on scanning pattern scanning substrate, make that titanium valve melting layer is cooling to be cemented on substrate;
S503, on fixed titanium valve layer, repave new titanium valve layer, and by scanning pattern, new titanium valve layer is carried out to laser scanning;
S504, repeating step S503, until the artificial complete molding of remporomandibular joint, the more artificial remporomandibular joint of molding is taken out from substrate.
In order to reach better processing effect, improve the machining accuracy of finished product, the power of described laser is 50-200W, and the spot diameter of laser is 50-180 μ m, and the scanning speed of laser is 50-500mm/s.The thickness of described titanium valve layer is 10-80 μ m; Described titanium valve layer is comprised of the pure titanium powder of spherical particle, and the pure titanium powder diameter of spherical particle is 10-100 μ m.
In the present embodiment, the power of the laser adopting is 100W, and the spot diameter of laser is 87 μ m, and the scanning speed of laser is 275mm/s.The thickness of the titanium valve layer adopting is 30 μ m; Described titanium valve layer is comprised of the pure titanium powder of spherical particle, and the pure titanium powder diameter of spherical particle is 30 μ m.
For preventing titanium valve oxidation in the course of processing, described step S501 is to step S504, and artificial remporomandibular joint workpiece all carries out processing and forming in the argon shield environment of 99.999wt.%.
A kind of artificial remporomandibular joint and manufacture method thereof based on selective laser melting technology provided by the present invention, adopts selective laser melting technology to carry out 3D printing shaping to artificial remporomandibular joint, and moulding material is the pure titanium with good biocompatibility.Before manufacturing artificial remporomandibular joint, first each patient's lower jaw is carried out to CT scan, obtain the lower jaw structure three-dimensional data of patient's reality, again according to each patient's lower jaw shape customized go out personalized artificial remporomandibular joint, thereby artificial remporomandibular joint of the present invention and patient's lower jaw structure degree of agreement is high.Meanwhile,
The pure titanium of moulding material has higher intensity, when guaranteeing that molding coincide individual patients physiological structure, guarantees the firm use of artificial remporomandibular joint of obtained by molding, to greatest extent real human body lower jaw structure is carried out to simulation making.
The above embodiment has only expressed one embodiment of the present invention, and it describes comparatively concrete and detailed, but can not therefore be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.

Claims (10)

1. the artificial remporomandibular joint based on selective laser melting technology, is characterized in that, comprising: condyle is prominent, neck of condyle portion and be provided with the titanium plate in nail hole; Condyle thumping arises from the trailing edge of neck of condyle portion upper end; Described titanium plate is arranged at neck of condyle subordinate end.
2. the artificial remporomandibular joint based on selective laser melting technology according to claim 1, is characterized in that: also comprise processus coracoideus; Described processus coracoideus is projected on the leading edge of neck of condyle portion upper end.
3. the artificial remporomandibular joint based on selective laser melting technology according to claim 2, is characterized in that: described condyle is prominent, neck of condyle portion and processus coracoideus, respectively equal and opposite in direction, the form symmetry of, neck of condyle portion prominent with the condyle of the strong side of patient's lower jaw and processus coracoideus.
4. the artificial remporomandibular joint based on selective laser melting technology according to claim 1, is characterized in that: the nail hole number on described titanium plate is no less than 2.
5. a manufacture method for the artificial remporomandibular joint based on selective laser melting technology, is characterized in that, comprises the following steps:
S1, scanning, obtain the temporomandibular basic three-dimensional profile data of patient by CT scan;
S2, modeling, basic three-dimensional profile data are processed, according to operation osteotomy situation, by strong side block that more than plane condyle is prominent, neck of condyle portion and beak lug structure do sagittal plane upset, and add in the cheek side of upset condyle cervical region lower end the titanium plate fitting like a glove with mandible surface, to set up the three dimensional computer modeling of described artificial remporomandibular joint;
S3, connection design, connect design to the three dimensional computer modeling of described artificial remporomandibular joint;
S4, generating process parameter, carry out layering processing to the three dimensional computer modeling of described artificial remporomandibular joint, generates corresponding scanning pattern, preserves and derive corresponding technological parameter;
S5,3D print, and described technological parameter is imported to 3D printing device, carry out 3D printing;
S6, sandblast, print to 3D the semi-finished product that make and carry out blasting treatment.
6. the manufacture method of the artificial remporomandibular joint based on selective laser melting technology according to claim 5, is characterized in that: described step S5 specifically comprises the following steps:
S501, described 3D printing device are provided with substrate, titanium valve layer on uniform spreading on substrate;
S502, utilize superlaser by the titanium valve layer on scanning pattern scanning substrate, make that titanium valve melting layer is cooling to be cemented on substrate;
S503, on fixed titanium valve layer, repave new titanium valve layer, and by scanning pattern, new titanium valve layer is carried out to laser scanning;
S504, repeating step S503, until the artificial complete molding of remporomandibular joint, the more artificial remporomandibular joint of molding is taken out from substrate.
7. the manufacture method of the artificial remporomandibular joint based on selective laser melting technology according to claim 5, is characterized in that: described technological parameter comprises scan mode, scanning speed, power and the spot diameter of putting position, disposing way and the laser of artificial remporomandibular joint workpiece.
8. the manufacture method of the artificial remporomandibular joint based on selective laser melting technology according to claim 7, it is characterized in that: the power of described laser is 50-200W, the spot diameter of laser is 50-180 μ m, and the scanning speed of laser is 50-500mm/s.
9. the manufacture method of the artificial remporomandibular joint based on selective laser melting technology according to claim 6, is characterized in that: the thickness of described titanium valve layer is 10-80 μ m; Described titanium valve layer is comprised of the pure titanium powder of spherical particle, and the pure titanium powder diameter of spherical particle is 10-100 μ m.
10. the manufacture method of the artificial remporomandibular joint based on selective laser melting technology according to claim 6; it is characterized in that: described step S501 is to step S504, and artificial remporomandibular joint workpiece all carries out processing and forming in the argon shield environment of 99.999wt.%.
CN201310712553.5A 2013-12-20 2013-12-20 Artificial temporal-mandibular joint based on selective laser melting technology and manufacturing method thereof Pending CN103750923A (en)

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CN104498940A (en) * 2014-12-03 2015-04-08 中国航空工业集团公司北京航空材料研究院 Method of manufacturing titanium-alloy artificial joints by virtue of laser material increase
CN104887352A (en) * 2015-05-12 2015-09-09 上海交通大学医学院附属第九人民医院 Artificial temporal-mandibular joint replacement prosthesis
CN105055037A (en) * 2015-07-27 2015-11-18 广州中国科学院先进技术研究所 Individual abutment and manufacturing method thereof
CN105105838A (en) * 2015-07-27 2015-12-02 广州中国科学院先进技术研究所 Personalized maxillofacial surgery guide plate and manufacturing method thereof
CN105380712A (en) * 2015-10-27 2016-03-09 李泽福 Guiding stent based on 3D printing and used for cerebral hemorrhage minimally invasive surgery and preparation method thereof
CN105616040A (en) * 2016-03-18 2016-06-01 广州市健齿生物科技有限公司 Porous artificial temporal-mandibular joint structure and making method
CN105686875A (en) * 2016-03-19 2016-06-22 傅山泓 Personalized bone plate and manufacturing method thereof
CN105919664A (en) * 2016-06-14 2016-09-07 广州雄俊智能科技有限公司 Personalized bone plate and manufacturing method thereof
CN106562842A (en) * 2016-11-09 2017-04-19 广州医科大学附属口腔医院 Artificial temporomandibular joint based on three-dimensional printing
CN107334544A (en) * 2017-02-13 2017-11-10 上海威宁整形制品有限公司 A kind of method for the expander for meeting biomethanics using the customization of laser scanning, finite element analysis and 3D printing technique
WO2017195022A1 (en) * 2016-05-12 2017-11-16 Cadskills Bvba Prosthesis for a temporomandibular joint
CN110251275A (en) * 2019-05-22 2019-09-20 西安医学院 A kind of design method of personalization condyle prosthesis
CN110811929A (en) * 2019-11-07 2020-02-21 西安交通大学 Personalized lower limb long bone segment substitute and preparation method thereof
CN111973807A (en) * 2020-08-31 2020-11-24 四川大学 Bionic artificial temporomandibular joint disc and preparation method thereof
CN111973322A (en) * 2020-09-25 2020-11-24 上海交通大学医学院附属第九人民医院 Fixing plate for blocking temporomandibular joint anterior dislocation

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