CN105377341B - 药物输送装置 - Google Patents

药物输送装置 Download PDF

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Publication number
CN105377341B
CN105377341B CN201480040077.XA CN201480040077A CN105377341B CN 105377341 B CN105377341 B CN 105377341B CN 201480040077 A CN201480040077 A CN 201480040077A CN 105377341 B CN105377341 B CN 105377341B
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China
Prior art keywords
dose
drug delivery
delivery device
housing
cartridge
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Active
Application number
CN201480040077.XA
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English (en)
Chinese (zh)
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CN105377341A (zh
Inventor
T·奥克利
K·休森
S·米尔恩
M·帕伍尔斯基
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
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Sanofi Aventis France
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Publication of CN105377341A publication Critical patent/CN105377341A/zh
Application granted granted Critical
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525Dosing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566Means improving security or handling thereof
    • A61M5/3157Means providing feedback signals when administration is completed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31536Blocking means to immobilize a selected dose, e.g. to administer equal doses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31541Means preventing setting of a dose beyond the amount remaining in the cartridge
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159Dose expelling manners
    • A61M5/31593Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403Ampoule inserted into the ampoule holder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3125Details specific display means, e.g. to indicate dose setting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31536Blocking means to immobilize a selected dose, e.g. to administer equal doses
    • A61M2005/3154Blocking means to immobilize a selected dose, e.g. to administer equal doses limiting maximum permissible dose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201480040077.XA 2013-07-17 2014-07-17 药物输送装置 Active CN105377341B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13176883.0 2013-07-17
EP13176883 2013-07-17
PCT/EP2014/065340 WO2015007821A1 (en) 2013-07-17 2014-07-17 Drug delivery device

Publications (2)

Publication Number Publication Date
CN105377341A CN105377341A (zh) 2016-03-02
CN105377341B true CN105377341B (zh) 2020-08-04

Family

ID=48795456

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480040077.XA Active CN105377341B (zh) 2013-07-17 2014-07-17 药物输送装置

Country Status (6)

Country Link
US (1) US10596323B2 (enExample)
EP (1) EP3021911B1 (enExample)
JP (1) JP6426172B2 (enExample)
CN (1) CN105377341B (enExample)
DK (1) DK3021911T3 (enExample)
WO (1) WO2015007821A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6535666B2 (ja) * 2013-11-22 2019-06-26 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 用量終了フィードバック(end of dose feedback)を有する薬物送達デバイス
EP3187217A1 (en) * 2015-12-29 2017-07-05 Galderma S.A. Syringe with click mechanism
US11135376B2 (en) * 2016-03-15 2021-10-05 Sanofi Dosing mechanism for multi-shot injection device comprising flexible ratchet element
GB201615455D0 (en) 2016-09-12 2016-10-26 Norton Healthcare Ltd Last dose protection
US10688247B2 (en) * 2017-07-13 2020-06-23 Haselmeier Ag Injection device with flexible dose selection
US11969583B2 (en) 2018-07-17 2024-04-30 Medmix Switzerland Ag Injection device with dose interruption fail safe
CN212491038U (zh) * 2020-03-18 2021-02-09 苏州天健云康信息科技有限公司 液体给药装置

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5112317A (en) * 1988-01-22 1992-05-12 Nosta Ag Injection device
EP0554995A1 (en) * 1992-02-04 1993-08-11 Becton, Dickinson and Company Reusable medication delivery pen
CN101227942A (zh) * 2005-07-27 2008-07-23 诺沃-诺迪斯克有限公司 具有剂量限制机构和另外的安全机构的注射器设备
WO2011060786A1 (en) * 2009-11-20 2011-05-26 Moeller Claus Schmidt Spring actuated dose delivery device
CN102905613A (zh) * 2010-03-22 2013-01-30 赛诺菲-安万特德国有限公司 用于确定与医疗装置相关的信息的装置和方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62119944U (enExample) * 1986-01-20 1987-07-30
US5312347A (en) * 1992-02-27 1994-05-17 Osborne Barbara J Hypodermic needle shield
US5957896A (en) * 1997-08-11 1999-09-28 Becton, Dickinson And Company Medication delivery pen
US6945961B2 (en) * 2002-07-10 2005-09-20 Novo Nordisk A/S Injection device
GB0304822D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
DE102005043805A1 (de) * 2005-09-14 2007-03-22 Tecpharma Licensing Ag Zentrierhilfe zum Aufsetzen einer Nadel auf ein Injektionsgerät

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5112317A (en) * 1988-01-22 1992-05-12 Nosta Ag Injection device
EP0554995A1 (en) * 1992-02-04 1993-08-11 Becton, Dickinson and Company Reusable medication delivery pen
CN101227942A (zh) * 2005-07-27 2008-07-23 诺沃-诺迪斯克有限公司 具有剂量限制机构和另外的安全机构的注射器设备
WO2011060786A1 (en) * 2009-11-20 2011-05-26 Moeller Claus Schmidt Spring actuated dose delivery device
CN102905613A (zh) * 2010-03-22 2013-01-30 赛诺菲-安万特德国有限公司 用于确定与医疗装置相关的信息的装置和方法

Also Published As

Publication number Publication date
WO2015007821A1 (en) 2015-01-22
DK3021911T3 (da) 2021-10-11
CN105377341A (zh) 2016-03-02
EP3021911A1 (en) 2016-05-25
US20160151574A1 (en) 2016-06-02
JP2016524978A (ja) 2016-08-22
HK1219450A1 (zh) 2017-04-07
EP3021911B1 (en) 2021-07-14
JP6426172B2 (ja) 2018-11-21
US10596323B2 (en) 2020-03-24

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