CN105362838A - Oral liquid capable of relieving xerostomia - Google Patents
Oral liquid capable of relieving xerostomia Download PDFInfo
- Publication number
- CN105362838A CN105362838A CN201510853196.3A CN201510853196A CN105362838A CN 105362838 A CN105362838 A CN 105362838A CN 201510853196 A CN201510853196 A CN 201510853196A CN 105362838 A CN105362838 A CN 105362838A
- Authority
- CN
- China
- Prior art keywords
- parts
- xerostomia
- radix
- oral liquid
- rhizoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
- A61K36/515—Gentiana
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses an oral liquid capable of relieving xerostomia. The oral liquid is prepared from, by weight, 25-32 parts of Smilax china L., 9-16 parts of Pilea lomatogramma Hand.- Mazz, 9-16 parts of ligustrum lucidum ait, 10-18 parts of Rubus parvifolius L. root, 10-18 parts of rhizoma cimicifugae, 10-18 parts of sanguisorba officinalis, 9-16 parts of radix pseudostellariae, 3-5 parts of rhizoma coptidis, 3-6 parts of gentian and 6-9 parts of inula japonica through decocting and extracting. The oral liquid is capable of promoting the secretion of salivary glands and relieving the xerostomia and can be used for relieving the xerostomia caused by various factors.
Description
Technical field
The invention belongs to technical field of Chinese medicine, in particular to a kind of oral liquid alleviating xerostomia, particularly relate to a kind of oral liquid alleviating xerostomia after nasopharyngeal carcinoma radiotherapy.
Background technology
Nasopharyngeal carcinoma (nasopharyngealcarcinoma, NPC) is a kind of malignant tumor occurring in nasopharynx part, one of modal malignant neoplastic disease of Ye Shi China.The sickness rate of nasopharyngeal carcinoma is variant because of the difference of area, sex and age.China and south east asia are common.The mortality rate of nasopharyngeal carcinoma accounts for 2.81% of national malignant tumor mortality rate, and the Guangdong of China, Guangxi, Fujian, Hunan, Jiangxi sickness rate are the highest, and the particularly Midwest in Guangdong, annual morbidity may be up to 30,50/,100,000, and Guangxi occupies the whole nation second.The total incidence of China accounts for global 80% more than, and annual morbidity is 10,25/,100,000, and whole world the incidence rate in an average annual is below 1,/10 ten thousand; The ratio of its men and women's morbidity is about 3.5:1; The morbidity of nasopharyngeal carcinoma was risen by 20 years old, was onset peak period to the age of 5060 years old.The clinical cardinal symptom of nasopharyngeal carcinoma has nasal obstruction, nasal bleeding, often goes to a doctor with metastasic cervical lymph nodes.
At present, the first-selected radiotherapy of the therapeutic modality of nasopharyngeal carcinoma.While lonizing radiation kill cancerous cell, the normal structure of lonizing radiation route and tumor vicinity is also inevitably subject to irradiation and causes damage, and irradiated region salivary gland gland tissue damages, and modal complication is then xerostomia.The saliva of being secreted by the parotid gland, submaxillary gland, sublingual gland in oral cavity accounts for 90% of saliva total amount, and other 10% is by small glandular secretion.When main salivary gland is when radiating in open country, the forfeiture of salivary gland function just may be there is.After current treatment radiotherapy, the Therapeutic Method of xerostomia has the Drug therapys such as salivary gland substitution method, antibacterial irrigation, hard sugar method, fluoride and pilocarpine, but all dissatisfied (ZlmmermanR.P. of curative effect, MarkR.J., TranL.M., etal.Concomitantpilocarpineduringheadandneckirradiationr educesxerostomiaInt [J] .RadiatOncolBiolPhys, 1997,36:571-575.).
Summary of the invention
In view of the deficiencies in the prior art, the object of the invention is to by furtheing investigate Chinese Traditional Medicine, the oral liquid of xerostomia after a kind of eutherapeutic alleviation nasopharyngeal carcinoma radiotherapy is provided.
In order to realize object of the present invention, inventor is studied by lot of experiments, finally obtains following technical scheme:
Alleviate an oral liquid for xerostomia, be prepared from through water boiling and extraction by the Chinese crude drug of following mass parts: Rhizoma Smilacis Chinensis 25-32 part, Pilea lomatogramma Hand.-Mazz 9-16 part, Fructus Ligustri Lucidi 9-16 part, radix rubi parvifol 10-18 part, Rhizoma Cimicifugae 10-18 part, Radix Sanguisorbae 10-18 part, Radix Pseudostellariae 9-16 part, Rhizoma Coptidis 3-5 part, Radix Gentianae 3-6 part, Flos Inulae 6-9 part.
Preferably, the oral liquid of described alleviation xerostomia, is prepared from through water boiling and extraction by the Chinese crude drug of following mass parts: Rhizoma Smilacis Chinensis 28-30 part, Pilea lomatogramma Hand.-Mazz 11-13 part, Fructus Ligustri Lucidi 11-13 part, radix rubi parvifol 14-16 part, Rhizoma Cimicifugae 14-16 part, Radix Sanguisorbae 14-16 part, Radix Pseudostellariae 11-13 part, Rhizoma Coptidis 3-5 part, Radix Gentianae 4-6 part, Flos Inulae 7-8 part.
Further preferably, the oral liquid of described alleviation xerostomia, is prepared from through water boiling and extraction by the Chinese crude drug of following mass parts: Rhizoma Smilacis Chinensis 29 parts, Pilea lomatogramma Hand.-Mazz 12 parts, Fructus Ligustri Lucidi 12 parts, radix rubi parvifol 15 parts, Rhizoma Cimicifugae 15 parts, Radix Sanguisorbae 15 parts, Radix Pseudostellariae 12 parts, Rhizoma Coptidis 4 parts, Radix Gentianae 5 parts, Flos Inulae 8 parts.
It should be noted that, oral liquid of the present invention in preparation process adopt the source of traditional Chinese medicinal material raw materials as follows: Rhizoma Smilacis Chinensis selects the dry root stock of Liliaceae smilax plant Rhizoma Smilacis Chinensis SmilaxchinaL.; Pilea lomatogramma Hand.-Mazz selects the dry herb of contrayerva grand arteries and veins Rhizoma Belamcandae PilealomatogrammaHand.-Mazz; Fructus Ligustri Lucidi selects the dry mature fruit of Oleaceae plants Fructus Ligustri Lucidi LigustrumlucidumAit.; Radix rubi parvifol selects the dry root of rosaceous plant Rubus Parvifolius L. RubusparvifoliusL.; The dry rhizome of ranunculaceae plant Rhizoma Cimicifugae CimicifugafoetidaL. selected by Rhizoma Cimicifugae; Radix Sanguisorbae selects the dry root of rosaceous plant Radix Sanguisorbae SanguisorbaofficinalisL.; Radix Pseudostellariae selects the dried root of pinkwort Radix Ginseng Pseudostellariaheterophylla (Miq.) PaxexPaxetHoffm.; Rhizoma Coptidis selects the dry rhizome of ranunculaceae plant Rhizoma Coptidis CoptischinensisFranch.; Radix Gentianae selects the dry root and rhizome of gentianaceae plant Radix Gentianae GentianascabraBunge; Flos Inulae selects the dry capitulum of feverfew Flos Inulae InulajaponicaThunb..
Compared with prior art, the Chinese medicine oral liquid that the present invention relates to has the effect promoting salivary gland secretion, alleviate xerostomia, can be used for the alleviation xerostomia that alleviation various factors causes.In addition, the present invention can keep oral cavity moistening, and clean, appetite stimulator, also can reduce the sense of discomfort that nasopharyngeal carcinoma radiotherapy causes, and obviously can reduce the misery of patient, improves the quality of life of patient.
Detailed description of the invention
Be below specific embodiments of the invention, technical scheme of the present invention is done to describing further, but protection scope of the present invention be not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
The preparation of embodiment 1 Chinese medicine oral liquid
Crude drug prescription: Rhizoma Smilacis Chinensis 2.9kg, Pilea lomatogramma Hand.-Mazz 1.2kg, Fructus Ligustri Lucidi 1.2kg, radix rubi parvifol 1.5kg, Rhizoma Cimicifugae 1.5kg, Radix Sanguisorbae 1.5kg, Radix Pseudostellariae 1.2kg, Rhizoma Coptidis 0.4kg, Radix Gentianae 0.5kg, Flos Inulae 0.8kg.
Preparation technology: the above-mentioned Chinese crude drug taking recipe quantity, merges, and pulverizes, put in multi-function extractor and decoct with water twice, add up the water of medical material 12 times amount for the first time, decoct 2h, get decocting liquid, filter, second time adds up the water of medical material 10 times amount, decoct 1.5h, get twice decocting liquid and merge, filter, be concentrated into every milliliter containing 1.2g crude drug amount, stir, put 5 DEG C of deepfreeze 24h, cold preservation liquid is filtered, adds appropriate antiseptic, obtain oral liquid.
The preparation of embodiment 2 Chinese medicine oral liquid
Crude drug prescription: Rhizoma Smilacis Chinensis 2.5kg, Pilea lomatogramma Hand.-Mazz 1.6kg, Fructus Ligustri Lucidi 1.6kg, radix rubi parvifol 1.6kg, Rhizoma Cimicifugae 1.6kg, Radix Sanguisorbae 1.6kg, Radix Pseudostellariae 1.2kg, Rhizoma Coptidis 0.5kg, Radix Gentianae 0.5kg, Flos Inulae 0.9kg.
Preparation technology: the above-mentioned Chinese crude drug taking recipe quantity, merges, and pulverizes, put during multi-functional extraction is filled with and decoct with water twice, add up the water of medical material 12 times amount for the first time, decoct 2h, get decocting liquid, filter, second time adds up the water of medical material 10 times amount, decoct 2h, get twice decocting liquid and merge, filter, be concentrated into every milliliter containing 1.1g crude drug amount, stir, put 5 DEG C of deepfreeze 24h, cold preservation liquid is filtered, adds appropriate antiseptic, obtain oral liquid.
Embodiment 3: Chinese medicine oral liquid is to the effectiveness study of xerostomia patient after nasopharyngeal carcinoma radiotherapy
Nasopharyngeal carcinoma accepts xerostomia patient totally 31 examples after radical radiation therapy, and without xerostomia sense before patient radiation treats, after radiotherapy, xerostomia is obvious, needs drinking-water, semi-fluid or liquid diet when feed or speech, and cooked rice of taking food must accompany soup.All patients are divided into test group 16 example and matched group 15 example at random.Test group man 9 example, female 7 example; 37 ~ 61 years old age, average 48.3 years old.Matched group man 8 example, female 7 example; 38 ~ 63 years old age, average 48.5 years old.Two groups of physical data comparing difference not statistically significants, have comparability.Test group patient takes Chinese medicinal formulae of the present invention treatment, and prescription forms: Rhizoma Smilacis Chinensis 29g, Pilea lomatogramma Hand.-Mazz 12g, Fructus Ligustri Lucidi 12g, radix rubi parvifol 15g, Rhizoma Cimicifugae 15g, Radix Sanguisorbae 15g, Radix Pseudostellariae 12g, Rhizoma Coptidis 4g, Radix Gentianae 5g, Flos Inulae 8g.Every day 1 dose, be decocted in water for oral dose, add decocting 2 collecting decoctions and be about 300mL, every bu frequently sobs clothes 15 ~ 20 times.Matched group patient takes vitamin C 0.2g, every day 3 times.Two groups was all a course for the treatment of with 30 days.
Two groups treat a course for the treatment of after, according to Thirstiness scoring and the numerical value of stimulated saliva flow, after carrying out xerostomia treatment, comprehensive therapeutic effect is evaluated.Effective: Thirstiness scoring minimizing 2 points and more than, or the increase of stimulated saliva flow is more than or equal to 100%.Take a turn for the better: Thirstiness scoring minimizing 1 point, or stimulated saliva flow increases by 50% ~ 100%.Invalid: Thirstiness scoring constantly even increases, stimulated saliva flow reduces, constant or increase and be less than or equal to 50%.
By patient's Thirstiness by 0 ~ 4 five grade of scoring: 0 is divided into without xerostomia symptom; 1 is divided into suspicious xerostomia, sleep slight xerostomia when waking up, 2 be divided into persistent mild xerostomia, do not affect feed and speech, 3 are divided into lasting moderate xerostomia, need drinking-water, 4 are divided into burn feeling in lasting severe xerostomia, oral cavity, swallow dysmasesis, need with kettle when feed or speech.
The mensuration of dynamic salivation amount: fasting in morning on the same day, after clear water is gargled, chews 60 DEG C of warm water maceration paraffin 5g, spits in graduated cylinder after 10min, records full saliva amount.
Before and after two groups of treatments, Thirstiness scoring and stimulated saliva flow-rate ratio are comparatively in table 1, table 2.Two groups of Clinical efficacy comparisons are in table 3.
Before and after table 1 liang group treatment, Thirstiness scoring is compared (dividing)
With this group before treatment,
*p < 0.01; Compare with after treatment of control group,
#p < 0.01.Before and after table 2 liang group treatment, stimulated saliva flow-rate ratio comparatively (mL/10min)
With this group before treatment,
*p < 0.01; Compare with after treatment of control group,
#p < 0.01.
Table 3 liang group Clinical efficacy comparison [example (%)]
Claims (5)
1. alleviate the oral liquid of xerostomia for one kind, it is characterized in that, described oral liquid is prepared from through water boiling and extraction by the Chinese crude drug of following mass parts: Rhizoma Smilacis Chinensis 25-32 part, Pilea lomatogramma Hand.-Mazz 9-16 part, Fructus Ligustri Lucidi 9-16 part, radix rubi parvifol 10-18 part, Rhizoma Cimicifugae 10-18 part, Radix Sanguisorbae 10-18 part, Radix Pseudostellariae 9-16 part, Rhizoma Coptidis 3-5 part, Radix Gentianae 3-6 part, Flos Inulae 6-9 part.
2. alleviate the oral liquid of xerostomia according to claim 1, it is characterized in that, described oral liquid is prepared from through water boiling and extraction by the Chinese crude drug of following mass parts: Rhizoma Smilacis Chinensis 28-30 part, Pilea lomatogramma Hand.-Mazz 11-13 part, Fructus Ligustri Lucidi 11-13 part, radix rubi parvifol 14-16 part, Rhizoma Cimicifugae 14-16 part, Radix Sanguisorbae 14-16 part, Radix Pseudostellariae 11-13 part, Rhizoma Coptidis 3-5 part, Radix Gentianae 4-6 part, Flos Inulae 7-8 part.
3. alleviate the oral liquid of xerostomia according to claim 2, it is characterized in that, described oral liquid is prepared from through water boiling and extraction by the Chinese crude drug of following mass parts: Rhizoma Smilacis Chinensis 29 parts, Pilea lomatogramma Hand.-Mazz 12 parts, Fructus Ligustri Lucidi 12 parts, radix rubi parvifol 15 parts, Rhizoma Cimicifugae 15 parts, Radix Sanguisorbae 15 parts, Radix Pseudostellariae 12 parts, Rhizoma Coptidis 4 parts, Radix Gentianae 5 parts, Flos Inulae 8 parts.
4. according to the application of the arbitrary described Chinese crude drug compositions of claim 1-3 in the health product or medicine of preparation alleviation xerostomia.
5. application according to claim 4, is characterized in that, described xerostomia is the xerostomia that nasopharyngeal carcinoma radiotherapy causes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510853196.3A CN105362838A (en) | 2015-11-27 | 2015-11-27 | Oral liquid capable of relieving xerostomia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510853196.3A CN105362838A (en) | 2015-11-27 | 2015-11-27 | Oral liquid capable of relieving xerostomia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105362838A true CN105362838A (en) | 2016-03-02 |
Family
ID=55365789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510853196.3A Withdrawn CN105362838A (en) | 2015-11-27 | 2015-11-27 | Oral liquid capable of relieving xerostomia |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105362838A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112402320A (en) * | 2020-11-30 | 2021-02-26 | 深圳南粤药业有限公司 | Gargle for preventing and treating radioactive xerostomia and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103751579A (en) * | 2013-12-26 | 2014-04-30 | 柳州市中医院 | Pharmaceutical composition for treating oral mucositis caused by radiotherapy for nasopharyngeal carcinoma and preparation method of pharmaceutical composition |
| CN104127757A (en) * | 2014-07-15 | 2014-11-05 | 湖南龙石山铁皮石斛基地有限公司 | Traditional Chinese medicinal composition having body resistance strengthening and yin nourishing effects, and preparation method and application thereof |
| CN104740348A (en) * | 2015-04-13 | 2015-07-01 | 刘培进 | Medicine matched with radioactive therapy for nasopharyngeal carcinoma |
-
2015
- 2015-11-27 CN CN201510853196.3A patent/CN105362838A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103751579A (en) * | 2013-12-26 | 2014-04-30 | 柳州市中医院 | Pharmaceutical composition for treating oral mucositis caused by radiotherapy for nasopharyngeal carcinoma and preparation method of pharmaceutical composition |
| CN104127757A (en) * | 2014-07-15 | 2014-11-05 | 湖南龙石山铁皮石斛基地有限公司 | Traditional Chinese medicinal composition having body resistance strengthening and yin nourishing effects, and preparation method and application thereof |
| CN104740348A (en) * | 2015-04-13 | 2015-07-01 | 刘培进 | Medicine matched with radioactive therapy for nasopharyngeal carcinoma |
Non-Patent Citations (1)
| Title |
|---|
| 许毅: "血液肿瘤化疗后口腔黏膜炎的中药治疗体会", 《新中医》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112402320A (en) * | 2020-11-30 | 2021-02-26 | 深圳南粤药业有限公司 | Gargle for preventing and treating radioactive xerostomia and preparation method thereof |
| CN112402320B (en) * | 2020-11-30 | 2021-06-29 | 深圳南粤药业有限公司 | Gargle for preventing and treating radioactive xerostomia and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103169895A (en) | Traditional Chinese medicine used for losing weight | |
| CN101502588B (en) | Composition for beauty treatment and removing blain and method for preparing the same | |
| CN104758825A (en) | Traditional Chinese medicine composition for treating amenorrhea | |
| CN103055116B (en) | Traditional Chinese medicine composition for treating acnes | |
| CN103110762A (en) | Traditional Chinese medicine composition for treating old fracture | |
| CN105169212A (en) | Traditional Chinese medicine composition for treating chronic gastritis | |
| CN102397351A (en) | Traditional Chinese medicinal composition for treating insomnia | |
| CN104043077A (en) | Traditional Chinese medicine composition for tonifying qi and nourishing blood | |
| CN104173546A (en) | Traditional Chinese medicine liquid for treating rhinitis | |
| CN105362838A (en) | Oral liquid capable of relieving xerostomia | |
| CN104758406A (en) | Traditional Chinese medicine for treating endometritis | |
| CN105056170A (en) | Application of traditional Chinese medicine composition in preparing drug for treating acute gastritis | |
| CN101850073B (en) | Chinese medicinal composition for treating chronic pharyngitis | |
| CN104998005A (en) | Traditional Chinese medicine oral liquid special for treating constipation and preparation method thereof | |
| CN100542565C (en) | A kind of Chinese medicine for oral administration for the treatment of cephalagra type hemihidrosis disease | |
| CN104367878A (en) | Traditional Chinese medicine ointment for treating tinea of feet and hands and preparing method thereof | |
| CN104042923A (en) | Externally-applied cream for treating whelk | |
| CN101569722A (en) | New application of Chinese herbal medicaments of radix rehmanniae, figwort, dendrobium stem and oldenlandia for dispelling wind and eliminating dampness and treating acne | |
| CN101406538A (en) | Oral Chinese medicine for preventing and treating acne as well as preparation method and use thereof | |
| CN105663850A (en) | Traditional Chinese medicine composition for treating oral ulcer | |
| CN104173813A (en) | Foot bath powder for treating dysmenorrhea | |
| CN104606537A (en) | Qi-reinforcing and blood-nourishing medicated diet for improving chemotherapy-induced myocardial ischemic injury and preparation method | |
| CN104587251A (en) | Traditional Chinese medicine capsules for treating gout and preparation method thereof | |
| CN111991537A (en) | A Chinese medicinal composition for treating female hyperplasia of mammary glands and preventing canceration, and its preparation method | |
| CN106563111A (en) | Medicine and ointment for treating bedsore |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20160302 |