CN105362824A - Medicine for treating chronic hepatitis and preparation method thereof - Google Patents

Medicine for treating chronic hepatitis and preparation method thereof Download PDF

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CN105362824A
CN105362824A CN201510694018.0A CN201510694018A CN105362824A CN 105362824 A CN105362824 A CN 105362824A CN 201510694018 A CN201510694018 A CN 201510694018A CN 105362824 A CN105362824 A CN 105362824A
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dries
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薛学明
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Abstract

Hepatic inflammations of which disease courses and symptoms are relatively stable are collectively called chronic hepatitis which refers to the disease that hepatic cells are destroyed due to multiple factors such as viruses, heredity and diets, and the hepatic functions are damaged to cause a series of discomfortable body symptoms. The common clinical symptoms comprise anorexia, abdominal distension, oily food anorexia, nausea, emesis and easy fatigue. The invention provides a medicine which is prepared by selecting concha haliotidis, radix angelica sinensis, oysters, longan, nacre mothers of pearls, radix adenophorae, arabic cowry shells, pipewort, ruddle, dandelion, uncaria, fructus cannabis, gastrodia elata, bunge cherry seeds, tribulus terrestris, calabash, semen cassiae, exocarpium benincasae, glycine max seed coats, poria cocos, centipede, semen coicis, lumbricus, caulis spatholobi, apocynum venetum, trogopterus dung, spina date seeds, fructus crataegi, lucid ganoderma, artemisia anomala and malt through medical combination. The composition medicine has the effects of clearing heat, removing toxicity, tonifying Yin and removing deficiency and can remove the liver vacuity and turbidity, improve the liver function and enhance the whole body immunity.

Description

A kind of medicine for the treatment of chronic hepatitis and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of chronic hepatitis and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Chronic hepatitis is the general designation of the metastable inflammation of the course of disease and symptom.Refer to and by many factors etc. such as virus, heredity, diet, liver cell is damaged, the function of liver suffers damage, and causes a series of malaise symptoms of health.Clinical common sympton is loss of appetite, abdominal distention, detest greasy food, Nausea and vomiting, easily tired.Also there is abdomen jaundice in someone, urine color depth.The symptom of classic chronic hepatitis is slight and in intermittent, even for many years without any symptom.But want active treatment otherwise easily develop into hepatic ascites even liver cirrhosis.Because current Western medicine cannot treat chronic hepatitis fast and effectively, therefore there is great demand in the Chinese medicine of people to rapid, effective treatment chronic hepatitis, up to now, also do not find about relevant report of the present invention.
chronichepatitis is the general designation of the metastable hepatitis of course of disease symptom.Refer to and by many factors etc. such as virus, heredity, diet, the function of liver is suffered damage, cause a series of malaise symptoms of health.Clinical common sympton is loss of appetite, abdominal distention, detest greasy food, Nausea and vomiting, easily tired.Also there is abdomen jaundice in someone, urine color depth.The symptom of classic chronic hepatitis is slight and in intermittent, even for many years without any symptom.But want active treatment otherwise easily develop into hepatic ascites even liver cirrhosis.Because current Western medicine cannot treat hepatitis fast and effectively, therefore there is great demand in the Chinese medicine of people to rapid, effective treatment hepatitis, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment chronic hepatitis, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of effective treatment chronic hepatitis.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects Concha Haliotidis, Radix Angelicae Sinensis, Concha Ostreae, Arillus Longan, Concha Margaritifera, meat Radix Adenophorae (Radix Glehniae), Concha Erosariae seu Cypraeae, Flos Eriocauli, Haematitum, Herba Taraxaci, Ramulus Uncariae Cum Uncis, Fructus Cannabis, Rhizoma Gastrodiae, Semen Pruni, Fructus Atriplicis Sibiricae, calabash, Semen Cassiae, Exocarpium Benincasae, Testa sojae atricolor, Poria, Scolopendra, Semen Coicis, Pheretima, Caulis Spatholobi, Herba Apocyni veneti, Oletum Trogopterori, Semen Ziziphi Spinosae, Fructus Crataegi, Ganoderma, Herba Artemisiae Anomalae, Fructus Hordei Germinatus drug regimen formulated.The effect of void that this composition of medicine has heat-clearing and toxic substances removing, nourishing YIN is dispelled, dispels liver's void turbid, improves liver function, improves general immunity ability.Concha Haliotidis is selected to be because its salty in the mouth, cold in nature.Return Liver Channel.Function suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving.Cure mainly the conjunctival congestion and swelling pain of inflammation on dizzy, the headache of excessive rising of liver-YANG and wind-heat of liver channel, pterygium looks thing narco etc.In addition this product is forged with restraining antacid in addition, the effect of pain relieving, hemostasis, and for weary superacid gastric abscess of having a stomachache, as ground to the powder, external application can be used for traumatic hemorrhage.Radix Angelicae Sinensis is selected to be because its sweet in the mouth, pungent, warm in nature.Return liver, the heart, spleen channel.Function nourishes blood tonify deficiency, promoting blood circulation and stopping pain, loosening bowel to relieve constipation.Cure mainly all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea, before tire puerperal all disease deficiency and coldness, stomachache, injury from falling down, arthralgia pain, numbness, carbuncle, cellulitis, skin ulcer, infections etc.Concha Ostreae is selected to be because its sour in the mouth, cold nature.Return liver, stomach warp.Function suppressing the hyperactive liver and subsiding YANG, hard masses softening and resolving, convergence are astringent or styptic treatment for spontaneous sweating.Cure mainly hyperactivity of YANG due to deficiency of YIN, stirring-up of pathogenic wind in the interior resulting from deficiency card.Goiter, scrofula, sucutaneous nodule lump, hepatosplenomegaly, sweating due to debility, the slippage cards such as seminal emission, leukorrhagia, metrorrhagia.In addition this product is forged with still there being the effects such as antacid, pain relieving, hemostasis, and for stomachache, weary acid, vomiting, mix that to control incised wound hemorrhage outside porphyrize powder, modern age also replaces barium sulfate to do gastroscope radiography with Concha Ostreae powder.Arillus Longan is selected to be because its sweet in the mouth, warm in nature.GUIXIN, spleen channel.The function spleen that nourishes heart fills blood.Cure mainly deficiency of both the heart and spleen, palpitation with fear insomnia, forgetful, insufficiency of vital energy and blood, fatigue and weakness, sallow weak breath etc.In addition this product also has the merit of hemostasis, and to stool hematochezia, woman uterine bleeding etc. also can be applied.Select Concha Margaritifera to be because its taste, saltiness is trembled with fear.Return liver, heart channel.Function suppressing the hyperactive liver and subsiding YANG, the analgesic therapy of peace soul, liver heat removing and eyesight improving.Cure mainly syndrome of upper hyperactivity of liver yang; Irritability, demented, infantile convulsion, palpitation with fear insomnia, liver-fire conjunctival congestion and deficiency of the liver are dizzy; In addition this product porphyrize powder external energy dampness convergence, controls eczema pruritus.Radix Adenophorae (Radix Glehniae) is selected to be because its sweet in the mouth, cold nature.Attach to the lung and stomach meridians.Function nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.Cure mainly the deficiency of YIN scorching, cough, deficiency of stomach-Yin dry pharynx, dry mouth, constipation etc.Select Concha Erosariae seu Cypraeae to be because its salty in the mouth, property is put down.Return Liver Channel.Function checking hyperfunction of the liver for relieving convulsion, clearing away heat to improve acuity of vision.Cure mainly high heat, faint from fear and twitch, hyperactivity of YANG due to deficiency of YIN, vexed insomnia, flaming up of liver-fire conjunctival congestion and swelling pain etc.Select Flos Eriocauli to be because its sweet in the mouth, property is put down.Return stomach, Liver Channel.Function dispelling wind and heat pathogens, improving acuity of vision and removing nebula.Be mainly used in conjunctival congestion and swelling pain caused by wind heat diseases caused by exogenous pathogenic factor or Liver Channel wind-fire, the many tear of photophobia, pterygium etc.Haematitum is selected to be because its salty in the mouth, cold in nature.Return liver, heart channel.Function suppressing the hyperactive liver and subsiding YANG, lowering the adverse QI to relieve asthma, removing heat from blood, hemostasis.Cure mainly excessive rising of liver-YANG, have a dizzy spell, adverse rising of stomach-QI, singultus, eructation, vomiting, lung-QI being unable to descend, pant, QI rising in reverse order heat in blood, hemorrhage.Herba Taraxaci is selected to be because its bitter in the mouth, sweet, cold in nature.Return liver, stomach warp.Function heat-clearing and toxic substances removing, dampness removing is treating stranguria.Cure mainly pyretic toxicity carbuncle, skin infection, jaundice due to damp-heat and pyretic stranguria, dysuria.Ramulus Uncariae Cum Uncis is selected to be because its sweet in the mouth, cold nature.Return liver, pericardium channel.Function calming liver and clearing heat, endogenous wind stopping relieving convulsion.Cure mainly acute infantile convulsion wind, heat is got angry card; Liver Channel fire Sheng, syndrome of upper hyperactivity of liver yang etc.Select Fructus Cannabis to be because its sweet in the mouth, property is put down.Return spleen, large intestine channel.Function loosening bowel to relieve constipation.Be mainly used in dryness of the intestine constipation; In addition, this product external has the merit of moisturizing parasite killing.Can treat and deal with not raw and skin ulcer leprosy.Select Rhizoma Gastrodiae to be because its sweet in the mouth, property is put down.Return Liver Channel.Function suppressing the hyperactive liver and subsiding YANG, endogenous wind stopping relieving convulsion.Cure mainly syndrome of upper hyperactivity of liver yang; Syndrome of liver wind stirring up internally; Tetanus etc.In addition Rhizoma Gastrodiae still has the effect of wind-damp dispelling, can treat rheumatic arthralgia, numb limbs and tense tendons, hands and feet caused by paralysis etc.Select Semen Pruni to be because its acrid in the mouth, hardship, property is put down.Return spleen, large intestine, small intestine meridian.Function loosening bowel to relieve constipation, inducing diuresis to remove edema.Be mainly used in dryness of the intestine constipation and edema, beriberi, edema.Fructus Atriplicis Sibiricae is selected to be because its bitter in the mouth, pungent, property are put down.Return Liver Channel.Function suppressing the hyperactive liver and subsiding YANG, dispersing the stagnated live-QI to relieve the stagnation of QI, dispelling pathogenic wind for improving eyesight, antipruritic.Cure mainly excessive rising of liver-YANG, have a dizzy spell, depression of liver-QI, pain in chest and hypochondrium, scorching cataract in the wind heat such as menoxenia, galactostasis, acute mastitis, rubella, eczema, skin pruritus; Fructus Tribuli grinds that take after mixing it with water can curing vitiligo into powder in addition.Calabash is selected to be because its sweet in the mouth, light, cold in nature.Return lung, small intestine meridian.Function inducing diuresis to remove edema.Cure mainly edema, ascites is advisable with damp-heat syndrome.Semen Cassiae is selected to be because its sweet in the mouth, hardship, cold nature.Return liver, large intestine channel.Function liver heat removing and eyesight improving, suppressing liver-YANG, loosening bowel to relieve constipation.Cure mainly that inflammation in wind heat, conjunctival congestion and swelling pain, cataracta are dim-sighted, excessive rising of liver-YANG, have a dizzy spell, feeling of fullness in the head tinnitus, domination of heat dryness of the intestine, bitter taste constipation etc.Exocarpium Benincasae is selected to be because its sweet in the mouth, light, cold nature.Return lung, small intestine meridian.Function inducing diuresis to remove edema.Cure mainly edema distension, the card of dysuria.Select Testa sojae atricolor bean clothing to be because its sweet in the mouth, property is put down.Return Liver Channel.Function nourishes blood suppressing the hyperactive liver, YIN nourishing hidroschesis.Cure mainly blood-deficiency leading to hyperactivity of the liver, dizziness and headache and deficiency of YIN hectic fever, night sweat.Select Poria to be because its sweet in the mouth, light, property is put down.GUIXIN, spleen, kidney channel.Function promoting diuresis to eliminate damp pathogen, spleen-benefiting mind-tranquilizing.Be mainly used in water-damp retention, dysuria, edema, phlegm retention syndrome of spleen-deficiency and palpitation and insomnia etc.Scolopendra is selected to be because its acrid in the mouth, warm in nature.Return Liver Channel.Function endogenous wind stopping relieving convulsion, resolving mass and removing the obstruction of the collateral, pain relieving.Cure mainly infantile convulsion, apoplexy, tetanus, spasm tic, toxic swelling malignant boil, sucutaneous nodule, scrofula, venom and intractable headache, rheumatic arthralgia.Semen Coicis is selected to be because its sweet in the mouth, light, cold nature.Return spleen, stomach, lung, large intestine channel.Function eliminating dampness by diuresis spleen invigorating, detumescence eliminating impediment, clearing away heat and discharging pus.Be mainly used in dysuria, edema beriberi, diarrhea due to hypofunction of the spleen, rheumatic arthralgia and lung abscess, acute appendicitis etc.Pheretima is selected to be because its salty in the mouth, cold in nature.Return liver, spleen, urinary bladder channel.Function clearing heat for calming endogenous wind, dredging collateral of relievining asthma, diuresis.Cure mainly high fever, manic, twitch, epilepsy, expectorant heat syndrome cough is breathed heavily, pertussis, rheumatism arthromyodynia, apoplexy, hemiplegia, and joint swells and ache, accumulation of heat in the urinary bladder dysuria, sand Stranguria etc.Caulis Spatholobi is selected to be because its bitter in the mouth, micro-sweet, warm in nature.Return Liver Channel.Function promoting the circulation of blood is enriched blood, relaxing muscles and tendons and activating QI and blood in the collateral.Be mainly used in women's blood stasis, menoxenia, dysmenorrhea, amenorrhea, blood deficiency amenorrhea and joint aches, numb hand and foot, quadriplegia, rheumatic arthralgia etc.Herba Apocyni veneti is selected to be because its sweet in the mouth, hardship, warm in nature.Return liver, heart channel.Function heat clearing away suppressing the hyperactive liver, heart tonifying diuresis.Cure mainly the edema that the headache of excessive rising of liver-YANG or high liver fire, dizzy, irritated insomnia and water retention sun are strongly fragrant, dysuria.In recent years with this product treatment excessive rising of liver-YANG or high liver fire type hypertension and heart failure, the edema that renal insufficiency causes has certain curative effect.Oletum Trogopterori is selected to be because its bitter in the mouth, sweet, warm in nature.Return Liver Channel.Function promoting blood circulation and stopping pain, removing stasis to stop bleeding.Be mainly used in congestion retardance obstructed caused dysmenorrhea, amenorrhea, the metrorrhagia, menorrhagia etc. of puerperal abdonimal pain, chest pain, epigastric pain and silt resistance passages through which vital energy circulates escape of blood from meridians.In addition, this product still can separate snakeworm poison, for Serpentis, scorpion, centipete bite.Select Semen Ziziphi Spinosae to be because its sweet in the mouth, property is put down.GUIXIN, Liver Channel.Function tranquilizing by nourishing the heart, arresting sweating.Cure mainly blood deficiency, vexed insomnia, palpitation with fear uneasiness and the empty spontaneous perspiration of body, night sweat.Fructus Crataegi is selected to be because its sour in the mouth, sweet, slightly warm in nature.Return spleen, stomach, Liver Channel.Function promoting digestion and removing stagnation, promoting blood circulation to remove blood stasis.Be mainly used in retention of food and drink, resistance of becoming silted up puerperal, stomachache, lochiorrhea and hernia etc.; In recent years Fructus Crataegi Hypertension, coronary heart disease and hyperlipemia is used, hepatosplenomegaly etc.Select Fructus Hordei Germinatus to be because its sweet in the mouth, property is put down.Return liver, spleen, stomach warp.Function help digestion and in, galactopoiesis.Be mainly used in food stagnation not flower and ablactation; In addition, this product again can be soothing the liver, can make adjuvant for stagnation of QI due to depression of the liver, incoordination between the liver and spleen card.Select Ganoderma to be because its sweet in the mouth, property is put down.Return liver, the heart, lung meridian.Function invigorating qi and benefiting blood, tranquilizing by nourishing the heart, relieving cough and asthma.Cure mainly insufficiency of vital energy and blood health thin and weak, deficiency of both the heart and spleen, irritability, phlegm-damp cough with asthma.In addition in recent years also coronary heart diseases and angina pectoris is treated by this product, hepatitis hyperlipemia; The leukocyte that hypertension and many reasons cause reduces disease.Herba Artemisiae Anomalae is selected to be because its bitter in the mouth, warm in nature.GUIXIN, spleen channel.Function removing blood stasis stimulates the menstrual flow, eliminating stasis to stop pain, promoting digestion and removing stagnation.Be mainly used in the amenorrhea of congestion retardance, dysmenorrhea, puerperal abdonimal pain, the diseases such as traumatic injury silt pain and abdominal pain due to retention of food; If grind external application into powder, wound hemorrhage can be treated.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:
concha Haliotidis 15-30 grams fructus Cannabis 10-30 grams pheretima 5-15 grams
radix Angelicae Sinensis 5-15 grams rhizoma Gastrodiae 3-15 grams caulis Spatholobi 5-15 grams
concha Ostreae 10-30 grams semen Pruni 5-12 grams herba Apocyni veneti 3-12 grams
arillus Longan 9-20 grams fructus Atriplicis Sibiricae 6-15 grams oletum Trogopterori 3-10 grams
concha Margaritifera 3-10 grams calabash 15-30 grams semen Ziziphi Spinosae 10-18 grams
meat Radix Adenophorae (Radix Glehniae) 10-15 grams semen Cassiae 10-15 grams fructus Crataegi 10-30 grams
concha Erosariae seu Cypraeae 10-15 gram exocarpium Benincasae 15-30 grams ganoderma 3-15 grams
flos Eriocauli 6-15 grams testa sojae atricolor 6-15 grams herba Artemisiae Anomalae 10-30 grams
haematitum 10-30 gram poria 10-15 grams fructus Hordei Germinatus 30-120 gram
herba Taraxaci 10-30 grams scolopendra 1-6 grams
ramulus Uncariae Cum Uncis 10-15 grams semen Coicis 10-30 grams.
Be preferably:
concha Haliotidis 20 grams fructus Cannabis 20 grams pheretima 15 grams
radix Angelicae Sinensis 15 grams rhizoma Gastrodiae 15 grams caulis Spatholobi 15 grams
concha Ostreae 20 grams semen Pruni 12 grams herba Apocyni veneti 12 grams
arillus Longan 20 grams fructus Atriplicis Sibiricae 15 grams oletum Trogopterori 10 grams
concha Margaritifera 10 grams calabash 20 grams semen Ziziphi Spinosae 18 grams
meat Radix Adenophorae (Radix Glehniae) 15 grams semen Cassiae 15 grams fructus Crataegi 20 grams
concha Erosariae seu Cypraeae 15 grams exocarpium Benincasae 20 grams ganoderma 15 grams
flos Eriocauli 15 grams testa sojae atricolor 15 grams herba Artemisiae Anomalae 20 grams
haematitum 20 grams poria 15 grams fructus Hordei Germinatus 40 grams
herba Taraxaci 20 grams scolopendra 6 grams
ramulus Uncariae Cum Uncis 15 grams semen Coicis 20 grams.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Concha Haliotidis: this product is the shell of Bao Ke animal, summer, Qiu Erji catch, fleshing, cleaning, drying;
2, Radix Angelicae Sinensis: pick decontamination, cleans, moistening, and slightly dry in the air when being suitable for inside and outside humidity, section is dried;
3, Concha Ostreae: this product is the shell of Ostreidae animal, and the whole year all can gather, fleshing, cleans, dries, cleaning, drying, pulverize;
4, Arillus Longan: gather during fruit maturation, shady and cool place places, and the used time is except decapsidate;
5, Concha Margaritifera: be the nacreous layer of Pteriidae animal Margarita, geneva pearl pearl shellfish or several mussel shell of Unionidae animal, the whole year all can collect, and is boiled by shell aqueous alkali, and rinses, and scrapes off outer casting skin, is calcined to crisp;
6, Radix Adenophorae (Radix Glehniae): summer and autumn excavates, the removing aerial stem of plant and fibrous root and earth, clean, and slightly cool putting in boiling water is slightly scalded, and peels off crust while hot, dries;
7, Concha Erosariae seu Cypraeae: be used as medicine with shell, between 5 ~ July, fishes for from marine, except fleshing, cleans and dries;
8, Flos Eriocauli: this product is the head inflorescence of the dry zone scape of Eriocaulaceae plant Flos Eriocauli, is used as medicine, gathers during fall flowering knot pearl, dries, removing impurity, cutting,
Autumn end excavates, and removing fibrous root, after moisture slightly evaporates, is bundled into wisp, upper canopy, with pyrotechnics slowly smoke-dried beancurd;
9, Haematitum: this product is oxide-based mineral corundum race bloodstone, main containing iron sesquioxide, after excavating, except roguing stone;
10, Herba Taraxaci: herb of gathering when blooming summer and autumn or just bloom, dries;
11, Ramulus Uncariae Cum Uncis: be used as medicine with root, leaf is also medicinal, and the whole year can adopt, and section is dried, or using fresh herb;
12, Fructus Cannabis: gather during fruit maturation in autumn, removing impurity, dries;
13, Rhizoma Gastrodiae: excavate as " spring fiber crops " between 4 ~ May of spring; What excavated between 9 ~ October before the Beginning of Winter is " winter fiber crops ", and quality is better; Take advantage of after having dug and freshly wash away earth, with clear water or Alumen water slightly bubble, scrape off crust, decocting in water or steam the heart, section, spreads out and dries;
14, Semen Pruni: mature fruit of gathering in summer, autumn, removing sarcocarp and nucleocapsid, take out seed, dry;
15, Fructus Atriplicis Sibiricae: this product is the dry mature fruit of zygophyllaceae plant Fructus Tribuli, taps plant, dries, lay fruit during fruit maturation in autumn, removing impurity;
16, calabash: summer gathers when melon is gradually ripe gradually, first reams melon skin, then cuts sugar-preserved gourd, sugar-preserved gourd smoke-dried beancurd or dry in the shade;
17, Semen Cassiae: mature fruit of gathering autumn, dries, lays seed, removing impurity;
18, Exocarpium Benincasae: outer peel of pruning during edible Fructus Benincasae, cleans, dries;
19, Testa sojae atricolor: this product is the seed coat of Papilionaceae plant teata glycinis, collects time ripe, and removing impurity, cleans, dry;
20, Poria: excavate rear removing earth between spring and summer, bank up, diaphoresis, spreads out in the cool; Bank up, diaphoresis, so repeatedly make moisture major part scatter and disappear for several times, the existing wrinkle in surface, then person of not drying in the shade claims Poria again.After getting the peeling of fresh Poria, square-cut or rectangular blocks are dried in the shade and are claimed Poria block; In have Radix Pini massonianae person claim Poria cum Radix Pini;
21, Scolopendra: the Scolopendra of having gathered is put into basin, scald dead fast with hot boiled water, but Scolopendra can not be scalded rotten, get sharpening thin bamboo plate one end, length and width two ends equal to Scolopendra length and width thrust the head of Scolopendra under Hubei Province other end inject tail end, by means of the elastic force of bamboo chip, make Scolopendra stretch flattening, dry or dry; Not removing bamboo chip after drying with 50 is that a bag thin paper is wrapped to be placed in cylinder and deposited, and in cylinder, puts some Camphoras, and with Anti-moth-eating, cylinder should be placed on drying and sentence moisture proof and affect quality;
22, Semen Coicis: tap plant during fruit maturation in autumn, dry and lay fruit, then dry except decapsidate, yellowish-brown seed coat and impurity, collect kernel;
23, Pheretima: Pheretima will be taken from soil, removing impurity, clean dry is cut off;
24, Caulis Spatholobi: the whole year can adopt, and cuts down rattan, removing withe, cuts into inclined tab or is cut into long section, dry;
25, Herba Apocyni veneti: can only gather once in August with the First Year of seminal propagation, annual June and JIUYUE are respectively gathered once later, when first time gathers, before initial bloom stage, cut off apart from root 15 ~ 20cm, second time cuts off Herb from near-earth, the branch cut off is taken advantage of and is freshly taken sheet leaf, parch.Dry in the shade, dry after lay blade, color complete with blade is green is good; Fresh branch can be cut into short section of 1 ~ 2cm, dries
Or dry in the shade, by the leaf of drying, short section of loading cloth bag, be put in aeration-drying place and preserve;
26, Oletum Trogopterori: the whole year can gather, by the Ex-all of sandstone earth impurity;
27, Semen Ziziphi Spinosae: gather during time of the year when autumn changes into winter fruit maturation, goes sarcocarp and stone to get seed, and life is used or micro-stir-fry is used;
28, Fructus Crataegi: pick clean impurity, sieve enucleation; Putting the interior slow fire stir-fry of pot is faint yellow to outside, takes out, cools;
29, Ganoderma: stop water spray in before gathering 1 week, close ventilation doorway, plastic sheeting on passage ground paving, to collect the spore powder distributed, after spore distributes, cap changes software strategy into software-hardware strategy, there is no shallow white edge, color from light yellow changes bronzing into, when not regrowth thickens, and ripe Ganoderma of can gathering.Gather Ganoderma time from the excision of handle base portion shears or pluck with have gentle hands, dry in the shade in time after gathering, oven dry with good conditionsi or dry to water content to be 12%, to be Ganoderma finished product, pack, is placed in dry indoor preservation or sale; Finished product is dry with body, cap is plump, stem is sturdy, matter is hard, color is reddish brown, tool paint sample gloss person is good;
30, Herba Artemisiae Anomalae: aerial parts of gathering when the Summer Solstice, autumn end bloomed dries;
31, Fructus Hordei Germinatus: after being soaked in water by wheat grain, keeps suitable epidemic disaster, when plumelet grows to about 5mm, dries or cold drying;
Two, prepare
1, the Concha Haliotidis of described weight, Radix Angelicae Sinensis, Concha Ostreae, Arillus Longan, Concha Margaritifera, meat Radix Adenophorae (Radix Glehniae), Concha Erosariae seu Cypraeae, Flos Eriocauli, Haematitum, Herba Taraxaci, Ramulus Uncariae Cum Uncis, Fructus Cannabis, Rhizoma Gastrodiae, Semen Pruni, Fructus Atriplicis Sibiricae, calabash, Semen Cassiae, Exocarpium Benincasae, Poria, Testa sojae atricolor, Scolopendra, Semen Coicis, Pheretima, Caulis Spatholobi, Herba Apocyni veneti, Oletum Trogopterori, Semen Ziziphi Spinosae, Fructus Crataegi, Ganoderma, Herba Artemisiae Anomalae, Fructus Hordei Germinatus drug regimen is formulated.Decoct with water twice, first time adds water 8 times amount, and intense fire decocts boiling 10 minutes, then uses slow fire boiling 25 minutes, filter first time decoction liquor;
2, add water the medicinal residues after first time filtration 6 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters and to obtain second time decoction liquor;
3, merge twice decoction liquor, intense fire boils, then within 10 minutes, namely obtains medicinal liquid with slow fire boiling, is divided into four doses to take.
Medicine of the present invention has removing dampness removing toxic substances, and the function of removing heat from blood and promoting blood circulation, nourishing the blood and yin, is used for the treatment of chronic hepatitis instant effect, good effect, does not recur.
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get West Germany rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Overdose test group is 25ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 15 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's totally 36 examples for medical treatment.
2, diagnostic criteria
Chronic hepatitis is caused by multiple paathogenic factor, as virus, antibacterial, parasite, chemical toxicant, medicine, ethanol, role of autoimmune factors etc. make liver cell be damaged, the function of liver suffers damage, and common sympton comprises: loss of appetite, abdominal distention, detest greasy food, Nausea and vomiting, easily tired.Some patients sclera or xanthochromia, heating, dull pain in liver, hepatomegaly, tenderness.Usually said chronic hepatitis in our life, majority refers to viral chronic hepatitis, will not treat and can delay throughout one's life.Along with life fluctuation and Smoking And Drinking etc. are very easily converted into hepatic ascites liver cirrhosis.。
3, Therapeutic Method
Select above-mentioned medicament, take to patient, every twice-daily, each potion, take 6 days continuously.
4, efficacy assessment standard
Effective: chronic hepatitis symptom is fully recovered, recover normal.
Take a turn for the better: chronic hepatitis symptom alleviates, and progressively takes a turn for the better.
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
In above-mentioned treatment, by Drug therapy chronic hepatitis patient 36 example of the present invention, effective 33 examples of result, obvious effective rate is 91.67%, and take a turn for the better 2 examples, and improvement rate is 5.55%, and invalid 1 example, total effective rate is 97.22%.

Claims (2)

1. treat a medicine for chronic hepatitis, it is characterized in that: it is made up of the crude drug in following weight range:
2. medicine according to claim 1, wherein the consumption of each crude drug is:
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Concha Haliotidis: this product is the shell of Bao Ke animal, summer, Qiu Erji catch, fleshing, cleaning, drying;
2, Radix Angelicae Sinensis: pick decontamination, cleans, moistening, and slightly dry in the air when being suitable for inside and outside humidity, section is dried;
3, Concha Ostreae: this product is the shell of Ostreidae animal, and the whole year all can gather, fleshing, cleans, dries, cleaning, drying, pulverize;
4, Arillus Longan: gather during fruit maturation, shady and cool place places, and the used time is except decapsidate;
5, Concha Margaritifera: be the nacreous layer of Pteriidae animal Margarita, geneva pearl pearl shellfish or several mussel shell of Unionidae animal, the whole year all can collect, and is boiled by shell aqueous alkali, and rinses, and scrapes off outer casting skin, is calcined to crisp;
6, Radix Adenophorae (Radix Glehniae): summer and autumn excavates, the removing aerial stem of plant and fibrous root and earth, clean, and slightly cool putting in boiling water is slightly scalded, and peels off crust while hot, dries;
7, Concha Erosariae seu Cypraeae: be used as medicine with shell, between 5 ~ July, fishes for from marine, except fleshing, cleans and dries;
8, Flos Eriocauli: this product is the head inflorescence of the dry zone scape of Eriocaulaceae plant Flos Eriocauli, is used as medicine, gathers during fall flowering knot pearl, dries, removing impurity, cutting,
Autumn end excavates, and removing fibrous root, after moisture slightly evaporates, is bundled into wisp, upper canopy, with pyrotechnics slowly smoke-dried beancurd;
9, Haematitum: this product is oxide-based mineral corundum race bloodstone, main containing iron sesquioxide, after excavating, except roguing stone;
10, Herba Taraxaci: herb of gathering when blooming summer and autumn or just bloom, dries;
11, Ramulus Uncariae Cum Uncis: be used as medicine with root, leaf is also medicinal, and the whole year can adopt, and section is dried, or using fresh herb;
12, Fructus Cannabis: gather during fruit maturation in autumn, removing impurity, dries;
13, Rhizoma Gastrodiae: excavate as " spring fiber crops " between 4 ~ May of spring; What excavated between 9 ~ October before the Beginning of Winter is " winter fiber crops ", and quality is better; Take advantage of after having dug and freshly wash away earth, with clear water or Alumen water slightly bubble, scrape off crust, decocting in water or steam the heart, section, spreads out and dries;
14, Semen Pruni: mature fruit of gathering in summer, autumn, removing sarcocarp and nucleocapsid, take out seed, dry;
15, Fructus Atriplicis Sibiricae: this product is the dry mature fruit of zygophyllaceae plant Fructus Tribuli, taps plant, dries, lay fruit during fruit maturation in autumn, removing impurity;
16, calabash: summer gathers when melon is gradually ripe gradually, first reams melon skin, then cuts sugar-preserved gourd, sugar-preserved gourd smoke-dried beancurd or dry in the shade;
17, Semen Cassiae: mature fruit of gathering autumn, dries, lays seed, removing impurity;
18, Exocarpium Benincasae: outer peel of pruning during edible Fructus Benincasae, cleans, dries;
19, Testa sojae atricolor: this product is the seed coat of Papilionaceae plant teata glycinis, collects time ripe, and removing impurity, cleans, dry;
20, Poria: excavate rear removing earth between spring and summer, bank up, diaphoresis, spreads out in the cool; Bank up, diaphoresis, so repeatedly make moisture major part scatter and disappear for several times, the existing wrinkle in surface, then person of not drying in the shade claims Poria again.After getting the peeling of fresh Poria, square-cut or rectangular blocks are dried in the shade and are claimed Poria block; In have Radix Pini massonianae person claim Poria cum Radix Pini;
21, Scolopendra: the Scolopendra of having gathered is put into basin, scald dead fast with hot boiled water, but Scolopendra can not be scalded rotten, get sharpening thin bamboo plate one end, length and width two ends equal to Scolopendra length and width thrust the head of Scolopendra under Hubei Province other end inject tail end, by means of the elastic force of bamboo chip, make Scolopendra stretch flattening, dry or dry; Not removing bamboo chip after drying with 50 is that a bag thin paper is wrapped to be placed in cylinder and deposited, and in cylinder, puts some Camphoras, and with Anti-moth-eating, cylinder should be placed on drying and sentence moisture proof and affect quality;
22, Semen Coicis: tap plant during fruit maturation in autumn, dry and lay fruit, then dry except decapsidate, yellowish-brown seed coat and impurity, collect kernel;
23, Pheretima: Pheretima will be taken from soil, removing impurity, clean dry is cut off;
24, Caulis Spatholobi: the whole year can adopt, and cuts down rattan, removing withe, cuts into inclined tab or is cut into long section, dry;
25, Herba Apocyni veneti: can only gather once in August with the First Year of seminal propagation, annual June and JIUYUE are respectively gathered once later, when first time gathers, before initial bloom stage, cut off apart from root 15 ~ 20 centimetres, second time cuts off Herb from near-earth, the branch cut off is taken advantage of and is freshly taken sheet leaf, parch.Dry in the shade, dry after lay blade, color complete with blade is green is good; Fresh branch can be cut into short section of 1 ~ 2 centimetre, dries
Or dry in the shade, by the leaf of drying, short section of loading cloth bag, be put in aeration-drying place and preserve;
26, Oletum Trogopterori: the whole year can gather, by the Ex-all of sandstone earth impurity;
27, Semen Ziziphi Spinosae: gather during time of the year when autumn changes into winter fruit maturation, goes sarcocarp and stone to get seed, and life is used or micro-stir-fry is used;
28, Fructus Crataegi: pick clean impurity, sieve enucleation; Putting the interior slow fire stir-fry of pot is faint yellow to outside, takes out, cools;
29, Ganoderma: stop water spray in before gathering 1 week, close ventilation doorway, plastic sheeting on passage ground paving, to collect the spore powder distributed, after spore distributes, cap changes software strategy into software-hardware strategy, there is no shallow white edge, color from light yellow changes bronzing into, when not regrowth thickens, and ripe Ganoderma of can gathering.Gather Ganoderma time from the excision of handle base portion shears or pluck with have gentle hands, dry in the shade in time after gathering, oven dry with good conditionsi or dry to water content to be 12%, to be Ganoderma finished product, pack, is placed in dry indoor preservation or sale; Finished product is dry with body, cap is plump, stem is sturdy, matter is hard, color is reddish brown, tool paint sample gloss person is good;
30, Herba Artemisiae Anomalae: aerial parts of gathering when the Summer Solstice, autumn end bloomed dries;
31, Fructus Hordei Germinatus: after being soaked in water by wheat grain, keeps suitable epidemic disaster, when plumelet grows to about 5 millimeters, dries or cold drying;
Two, prepare
1, the Concha Haliotidis of described weight, Radix Angelicae Sinensis, Concha Ostreae, Arillus Longan, Concha Margaritifera, meat Radix Adenophorae (Radix Glehniae), Concha Erosariae seu Cypraeae, Flos Eriocauli, Haematitum, Herba Taraxaci, Ramulus Uncariae Cum Uncis, Fructus Cannabis, Rhizoma Gastrodiae, Semen Pruni, Fructus Atriplicis Sibiricae, calabash, Semen Cassiae, Exocarpium Benincasae, Poria, Testa sojae atricolor, Scolopendra, Semen Coicis, Pheretima, Caulis Spatholobi, Herba Apocyni veneti, Oletum Trogopterori, Semen Ziziphi Spinosae, Fructus Crataegi, Ganoderma, Herba Artemisiae Anomalae, Fructus Hordei Germinatus drug regimen is formulated.Decoct with water twice, first time adds water 8 times amount, and intense fire decocts boiling 10 minutes, then uses slow fire boiling 25 minutes, filter first time decoction liquor;
2, add water the medicinal residues after first time filtration 6 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters and to obtain second time decoction liquor;
3, merge twice decoction liquor, intense fire boils, then within 10 minutes, namely obtains medicinal liquid with slow fire boiling, is divided into four doses to take.
CN201510694018.0A 2015-10-25 2015-10-25 Medicine for treating chronic hepatitis and preparation method thereof Withdrawn CN105362824A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103638464A (en) * 2013-12-11 2014-03-19 张有富 Medicine for treating chronic hepatitis and preparation method of medicine
CN103977306A (en) * 2014-05-28 2014-08-13 赵红侠 Medicament for treating hepatitis B and preparation method thereof
CN104173988A (en) * 2014-09-04 2014-12-03 薛学明 Medicine for treating cold and preparation method thereof
CN104338083A (en) * 2014-11-04 2015-02-11 薛学明 Medicament for treating irregular menstruation and preparation method thereof
CN104906330A (en) * 2015-06-14 2015-09-16 孙太辉 Medicine for treating pruritus cutanea and preparation method of medicine

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103638464A (en) * 2013-12-11 2014-03-19 张有富 Medicine for treating chronic hepatitis and preparation method of medicine
CN103977306A (en) * 2014-05-28 2014-08-13 赵红侠 Medicament for treating hepatitis B and preparation method thereof
CN104173988A (en) * 2014-09-04 2014-12-03 薛学明 Medicine for treating cold and preparation method thereof
CN104338083A (en) * 2014-11-04 2015-02-11 薛学明 Medicament for treating irregular menstruation and preparation method thereof
CN104906330A (en) * 2015-06-14 2015-09-16 孙太辉 Medicine for treating pruritus cutanea and preparation method of medicine

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Application publication date: 20160302