CN105362739A - 一种具有安神作用的药物组合物 - Google Patents

一种具有安神作用的药物组合物 Download PDF

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CN105362739A
CN105362739A CN201510780901.1A CN201510780901A CN105362739A CN 105362739 A CN105362739 A CN 105362739A CN 201510780901 A CN201510780901 A CN 201510780901A CN 105362739 A CN105362739 A CN 105362739A
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许杰
许恩慈
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Zhou Rui
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Abstract

本发明公开一种具有安神作用的药物组合物。该组合物由麻黄、桂枝、葛根、芍药、知母、芒硝、半枝莲、枫香脂、白茯苓、艾叶、远志、首乌藤、合欢皮、茉莉花等20味原料药组成。本发明组合物按照常规工艺加入常规辅料制成临床接受的外用剂型，如卫生香、保健枕、酊剂、擦剂或喷雾剂等。本发明药物组合物无副作用、使用方便、成本低，对治疗失眠效果显著。

Description

一种具有安神作用的药物组合物
技术领域
本发明涉及一种药物组合物，特别是涉及一种具有安神作用的药物组合物。
背景技术
失眠症是一种常见的睡眠障碍，是睡眠质量或数量达不到正常要求的一种主观体验，其症状一般包括入睡困难、睡眠表浅、易醒、早醒、醒后难以再次入睡，以及醒后缺乏清醒感等。随着现代生活节奏的加快，患有失眠和神经衰弱的人越来越多。世界卫生组织曾在14个国家进行调查，约有27％的人有睡眠问题。中华医学会在5个大城市进行一次有1万多人的调查，存在易醒、醒得过早、睡眠时间不足、睡眠质量不好等睡眠问题的高达42.5％，特别是以妇女和老人居多。失眠严重地困扰着人们的工作、学习和生活质量。治疗失眠的药物虽然很多，但都不能立效、长效，西药类毒副作用大，大多有成瘾性。中药类的内服中成药虽然有安神补脑的功效，但疗效慢、治愈率低，且成本较高。
发明内容
本发明目的在于提供一种具有安神作用的药物组合物。
本发明是通过如下技术方案实现的：
本发明药物组合物的原料药组成为：
本发明药物组合物的原料药组成优选为：
本发明药物组合物的原料药组成优选为：
本发明药物组合物的原料药组成优选为：
本发明药物组合物按照常规工艺加入辅料制成临床接受的外用剂型，如卫生香、保健枕、酊剂、擦剂或喷雾剂等。
本发明药物组合物的优点在于：本发明是中医中药的传统烟薰剂，它通过人的呼吸作用于大脑神经，不仅发生作用快，很快达到催眠的效果，还可根据失眠的病程的不同，可选择烟薰时间长短来控制，这比中药的其他剂型有独到的优势，特别是现在化学合成药在治疗失眠症造成诸多毒副作用时，本发明无副作用、使用方便、成本低，对治疗失眠效果显著。
下面实验例和实施例用于进一步说明本发明，但不限于本发明。
实验例1
本发明安神药物组合物临床观察治疗失眠症100例，取得显著效果，现报告如下：
1、一般资料
本组100例患者中，男50例，女50例；年龄最小30岁，最大的65岁，平均47.5岁；病程最长的10年，最短1个月，平均1年6个月。
2、诊疗标准
患者的症状一般包括入睡困难、睡眠表浅、易醒、早醒、醒后难以再次入睡，以及醒后疲乏或缺乏清醒感等。
3、治疗方法
在睡眠前，点燃一支本发明安神卫生香(按照实施例1方法制备，每支6克，每天1支)放置床头一侧，周围不要置易燃物，且用小盘托放香座。点燃后的安神卫生香，袅袅香烟，馥馥芬芬，令人神经逐渐地放松，不知不觉地进入梦乡。
4、疗效标准
治愈：临床症状完全消失，睡眠正常。
显效：临床症状基本消失或明显减轻，但由白天情绪过喜、过悲、过兴奋，则效果欠佳。
有效：临床症状有所好转。
无效：治疗后症状无任何改变。
5、治疗结果
本发明安神卫生香治疗100例，治愈80例，占80％，显效15例，占15％；有效5例，占5％；总有效率100％。
6、典型病例
病例1李××，男，58岁，退休干部。每天到下午5时后，深感疲劳欲睡，但一上床就寂，即烦燥不安，不能入睡。也曾服用中药调整，便效果不佳，后使用本发明安神卫生香(按照实施例1方法制备，每支6克，每天1支)，睡前点燃一支安神香后，即缓缓入睡。坚持使用本发明卫生香5天后，失眠得到治愈，睡眠正常。
病例2张××，女，45岁，下岗工人。生活多受挫折，又患有产后筋骨病，造成白天精神不振，夜晚不能入睡。经使用本发明药枕(按照实施例2方法制备)5天后，情况大有好转，每晚能熟睡5个小时，继续使用5天后，失眠得到治愈，睡眠正常。
病例3王××，女，38岁，个体工商户。身体消瘦，又加上生意操劳过度，致成只能浅睡。经使用本发明擦剂(按照实施例3方法制备，于睡前擦于额头两侧)一周后，睡眠由浅睡变为深睡，欲状况良好，并渐渐发胖，继续使用5天后，失眠全愈。
病例4田××，女，30岁，私企文员。因婚姻挫折，至今未婚，入睡后动辄苏醒，醒后不能再次入睡，造成面黄肌瘦，萎靡不振。经使用本发明喷雾剂(按照实施例4方法制备，于睡前喷于额头两侧，并按摩5分钟)，5天后睡眠质量大有提高，继续使用5天后，每晚能熟睡6个小时，身体状况大有改善，再巩固使用5天后，失眠得到治愈，睡眠正常。
下述实施例均能实现上述实验例的效果。
具体实施方式
实施例1：
上述药物按照常规工艺加入常规辅料制成卫生香，每支6克，每天一次，每次1支，睡前点燃。
实施例2：
上述药物按照常规工艺装入无纺布袋内，每袋30克，将装有药物的无纺布袋放入枕头中即可。
实施例3：
上述药物按照常规工艺加入常规辅料制成擦剂。
实施例4：
上述药物按照常规工艺加入常规辅料制成喷雾剂。

Claims (8)

1.一种具有安神作用的药物组合物，其特征在于，该组合物的原料药组成为：
2.如权利要求1所述的组合物，其特征在于该组合物的原料药组成为：
3.如权利要求1所述的组合物，其特征在于该组合物的原料药组成为：
4.如权利要求1所述的组合物，其特征在于该组合物的原料药组成为：
5.如权利要求1-4之一所述的组合物，其特征在于该组合物按照常规工艺加入常规辅料制成临床接受的外用剂型。
6.如权利要求5所述的组合物，其特征在于所述外用剂型为卫生香、保健枕、酊剂、擦剂或喷雾剂。
7.如权利要求1-4之一所述的组合物在制备具有安神作用的药物中的应用。
8.如权利要求1-4之一所述的组合物在制备治疗失眠的药物中的应用。
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