CN105357960B - 具有定制特征的转基因动物 - Google Patents

具有定制特征的转基因动物 Download PDF

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Publication number
CN105357960B
CN105357960B CN201480024934.7A CN201480024934A CN105357960B CN 105357960 B CN105357960 B CN 105357960B CN 201480024934 A CN201480024934 A CN 201480024934A CN 105357960 B CN105357960 B CN 105357960B
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CN
China
Prior art keywords
promoter
keratin
nucleic acid
animal
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201480024934.7A
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English (en)
Chinese (zh)
Other versions
CN105357960A (zh
Inventor
詹姆士·韦斯特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MICE WITH HORNS LLC
Original Assignee
MICE WITH HORNS LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/837,405 external-priority patent/US20130212723A1/en
Application filed by MICE WITH HORNS LLC filed Critical MICE WITH HORNS LLC
Publication of CN105357960A publication Critical patent/CN105357960A/zh
Application granted granted Critical
Publication of CN105357960B publication Critical patent/CN105357960B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/101—Bovine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/02—Animal zootechnically ameliorated

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Environmental Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biochemistry (AREA)
  • Animal Husbandry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
CN201480024934.7A 2013-03-15 2014-03-15 具有定制特征的转基因动物 Expired - Fee Related CN105357960B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/837,405 US20130212723A1 (en) 2012-02-15 2013-03-15 Transgenic animals with customizable traits
US13/837,405 2013-03-15
PCT/US2014/029918 WO2014145196A2 (en) 2013-03-15 2014-03-15 Transgenic animals with customizable traits

Publications (2)

Publication Number Publication Date
CN105357960A CN105357960A (zh) 2016-02-24
CN105357960B true CN105357960B (zh) 2018-02-16

Family

ID=51538427

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480024934.7A Expired - Fee Related CN105357960B (zh) 2013-03-15 2014-03-15 具有定制特征的转基因动物

Country Status (9)

Country Link
EP (1) EP2967017A4 (enExample)
JP (1) JP2016512697A (enExample)
CN (1) CN105357960B (enExample)
AU (3) AU2014233317B2 (enExample)
BR (1) BR112015023414A2 (enExample)
CA (1) CA2906936A1 (enExample)
HK (1) HK1214732A1 (enExample)
MX (1) MX2015013253A (enExample)
WO (1) WO2014145196A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3060682B1 (en) 2013-10-25 2023-08-30 Livestock Improvement Corporation Limited Genetic markers and uses therefor
CN107022549B (zh) * 2017-04-19 2021-06-01 华中农业大学 黄颡鱼β防御素基因及其β防御素抗菌肽及其应用
CN107177630A (zh) * 2017-05-09 2017-09-19 华南农业大学 一种无外源标记基因的抗pcv2转基因猪制备方法
CN111206042B (zh) * 2020-02-25 2021-08-31 中国科学院昆明植物研究所 一种表达酮式类胡萝卜素的融合基因、重组载体及其应用
CN113564186B (zh) * 2021-07-16 2023-07-25 山西大学 苹果黄蚜Tre基因及其核酸干扰剂制备方法与应用
CN117016497B (zh) * 2023-08-23 2025-08-05 西部(重庆)科学城种质创制大科学中心 一种利用雌激素相关受体调控家蚕表皮黑色素形成的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1324100A (en) * 1998-10-27 2000-05-15 Anticancer, Inc. Method and model for hair pigmentation
US20040171824A1 (en) * 2001-03-05 2004-09-02 Scrable Heidi Jean A Lac operator-repressor system
US20110265192A1 (en) * 2008-09-05 2011-10-27 Syddansk Universitet Nuclear receptor sensor system in transgenic animal
BR112014020089A2 (pt) * 2012-02-15 2017-07-04 Mice With Horns Llc animais transgênicos com características que podem ser customizadas

Also Published As

Publication number Publication date
AU2019204084A1 (en) 2019-07-04
EP2967017A2 (en) 2016-01-20
HK1214732A1 (zh) 2016-08-05
CN105357960A (zh) 2016-02-24
MX2015013253A (es) 2016-04-07
AU2017213487A1 (en) 2017-08-31
CA2906936A1 (en) 2014-09-18
AU2017213487B2 (en) 2019-07-04
WO2014145196A2 (en) 2014-09-18
WO2014145196A3 (en) 2015-02-19
JP2016512697A (ja) 2016-05-09
AU2014233317B2 (en) 2017-08-31
BR112015023414A2 (pt) 2017-11-28
AU2014233317A1 (en) 2015-10-29
EP2967017A4 (en) 2016-11-09

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20180216

Termination date: 20200315