CN1053573C - Traditional Chinese medicine ointment for curing burns and preparing method - Google Patents

Traditional Chinese medicine ointment for curing burns and preparing method Download PDF

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CN1053573C
CN1053573C CN93106813A CN93106813A CN1053573C CN 1053573 C CN1053573 C CN 1053573C CN 93106813 A CN93106813 A CN 93106813A CN 93106813 A CN93106813 A CN 93106813A CN 1053573 C CN1053573 C CN 1053573C
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radix
medicine
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burn
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CN1096203A (en
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王大刚
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Abstract

The present invention relates to ointment for treating burns, which belongs to a traditional Chinese medicine. 22 traditional Chinese medicine ingredients are selected, and are prepared into a prior period medicine of fire purging and toxin eliminating burn cream with sesame oil and beeswax. 29 traditional Chinese medicine ingredients are selected, and are prepared into a correlative later period medicine of dual-oil tissue and skin regeneration promoting burn cream with sesame oil and beeswax. Proved by the application of clinical treatment, the ointment has the advantages of rapid pain relief, infection resistance and few scars after wound healing, and generally has no requirements of skin grafting for burn surfaces caused by third-degree burns. Besides, a sterile environment is de-emphasized during therapeutic processes, and the medicine has a healing rate of 96.4% and a total effective rate of 100%. Shallow second-degree burns can be healed within 8 days more or less, deep second-degree burns can be healed within 18 days more or less, shallow third-degree burns can be healed within 35 days more or less, and pulled tendon and exposed bone burns can be healed within 60 days more or less.

Description

Chinese medicine burn cream and method for making thereof
The present invention relates to a kind of is Chinese medicine burn cream of being processed into of Main Ingredients and Appearance and preparation method thereof with the natural drug.
Burn, scald are a kind of commonly encountered diseases, frequently-occurring disease.According to the incomplete statistics in recent years of related city burn center, the burn patient general mortality rate is 6.87%, and wherein burn surface area 80% above person's mortality rate is 60.59%.Illustrate that the burn clinical treatment still has certain degree of difficulty, especially extensive deep burn is the very high wound of mortality rate.Treatment total be divided into of modern medicine to burning: the prevention and the treatment of a burn shock, the 2nd, the control of burn infection and nutrition, the 3rd, the processing of complication of burn, the 4th, the covering of burn wound.Rational and effective is handled the key that wound surface is the treatment burn.Mostly with the antibiotic control infection, strict aseptic at present.Anesthesia cuts crust, cuts crust, from body skin or heterodermic graft flap coverage.In whole therapeutic process, deep burn often needs repeatedly to perform the operation, and needs higher nursing condition and equipment, brings great misery to burn patient.Traditional surgery of Chinese medicine treatment burn, the Huangdi's Internal Classics before more than 2,000 years all had record and elaboration to the Tang Dynasty " prescriptions worth thousand gold ".Had the Chinese medicine scald medicament that many treatments are scalded, burnt in recent years, wherein as " JINGWANHONG " scald medicine and " moist expose burn ointment " but do not emphasize aseptic environments when waiting medicine itself to have infection, treatment, need not to anaesthetize pain relieving and small-area burn, the characteristics that need not make skin graft etc.But the overall process (promptly repairing the phase to the granulation promoting skin) of treatment III degree burn from eschar phase, infection period, because III degree burn, the condition of the injury is heavy, the course of disease is long, and the pathology development and change are many, and its clinical therapeutic efficacy is still undesirable.
The objective of the invention is to keep and develop the advantage of Chinese Chinese medicine surgical intervention burn, on the basis of clinical practice, a kind of medicine that not only I, II degree burn is had better curative effect is proposed, and the burn medicine even more ideal to the therapeutic effect of deep burn wound.
The medicine basis that the present invention burns according to various treatments before, and own clinical practice, because the continuous development and the variation of deep burn wound symptom, formed a cover theory complete, system and a therapeutic scheme, wound surface debated with negative and positive disease, wound surface are debated disease, three degree quarterings are concluded negative and positive, grasp medication time, dialectical executing controlled by stages.
All burn initial stages are positive heat symptom-complex, but depth weight difference, I, II degree burn wound card belong to positive heat symptom-complex.III degree burn wound, fire-toxin occupies dark, and the rotten card of the burnt meat of skin belongs to excess of YANG disease.
(1) first early stage, I, the medicine for treatment of II degree, " Xiehuo Jiedu Shaoshang Gao ", the eliminating fire and detoxication pain relieving is gone positive heat to have " antiphlogistic antibacterial " and is impelled epithelial growth, reduces effects such as cicatrix, does not generally enter the second phase can heal.III degree wound surface, fire-toxin occupies dark, the burnt meat corruption of skin, with the Xiehuo Jiedu Shaoshang Gao treatment, clear pathogenic fire purging poison impels slough liquefaction, separate, come off, corruption is taken off about 5-10 days, and granulation tissue is fresh, and is scarlet, and pus is many, the pain of changing dressings, the rotten depletion of YANG is contained institute and is moved back, but still sun heat continues with applying ointment.Current period is equivalent to body fluid and oozes out the phase, acute infection period.
(2) second phase, III degree wound surface can enter the current period about 15-25 days, the wound surface granulation tissue does not have the high protruding part of significant depressions, tough and tensile densification, red light or pale red, pus do not have purulent secretion less or substantially, change dressings and painful alleviate or irregular silvery white color chips type skin island occurs, perithelium is grown to the center, and this island is the growth of centrifugal property, and the current period enters YIN and YANG in a relative equilibrium period " YIN and YANG in a relative equilibrium card ".
With " two oily granulation promoting burn cream " treatment, promoting blood circulation for tissue regeneration, reduces cicatrix at the granulation promoting skin, is beneficial to the medicine that granulation promoting promotes epithelial growth." current period is equivalent to the epithelial repair phase ".
Chinese medicine burn cream of the present invention has following characteristics:
1, Chinese medicinal ointment is substrate with the Oleum sesami, and lubricated permeability is strong, makes medicine can act on the burn lesion rapidly and plays therapeutic effect.
2, Chinese medicinal ointment is to the human normal tissue not damaged, and non-stimulated going from the exterior into the interior ground is accelerated slough liquefaction and separated.
3, two kinds of ointment have adapted to burn wound in the different pathological change of each stage, are beneficial to the regeneration and the reparation of tissue.
4, external therapy of Chinese herb can promote granulation tissue cell and epithelial hypertrophy and differentiation, promotes the healing of wound surface.
5, use Chinese medicine burn cream of the present invention, system does not have influence to the human body whole body, and the evaporation that reduces wound surface moisture content is lost, the wound surface microcirculation disturbance improves, and has shortened shock stage, has alleviated the damage to internal organs.Separate owing to quickened the liquefaction of slough, wound surface is in the physiological environment, and the flora in the tissue is difficult for producing imbalance, and it is less etc. to absorb septicemia chance that " bacteriotoxin " cause from wound surface.
The medication in early stage of Chinese medicine burn cream of the present invention: " Xiehuo Jiedu Shaoshang Gao " is with following medicine components (weight) processing and fabricating. (1) component: coptis 10-50 part ilex pubescens 25-35 part corydalis tuber 10-25 part subprostrate sophora 25-35 part radix ampelopsis 25-35 part garden burnet 15-25 part FOLIUM HIBISCI MUTABILIS 15-25 part cacumen biotae 25-35 part root bark of shaggy-fruited dittany 15-25 part isatis root 15-25 part golden cypress 25-35 part radix paeoniae rubrathe 25-35 part Asian puccoon 35-45 part pappy shell 15-25 part capsule of weeping forsythia 20-30 part root of Chinese trichosanthes 0-35 part first pearl 0-15 part beeswax 150-170 part vaseline 0-1250 part sesame oil 250-1700 part
(2) group (powder)
Mirabilitum crystallina 30-55 part Gypsum Fibrosum 30-55 part
Semen Phaseoli 0-35 part calamitas urinae hominis 25-35 part
(3) group (powder)
Artificial Calculus Bovis 1.5-2.5 part Borneolum Syntheticum 4-8 part
At first Rhizoma Coptidis, Radix Ilicis Pubescentis are smashed, the medicine that (2) are organized is ground into fine powder jointly, crosses the 100-120 mesh sieve, and the medicine that (3) are organized is ground into fine powder jointly, and it is standby to cross the 100-120 mesh sieve.Its processing step is that (1) group Chinese medicine component was soaked 1-3 days in 250-1700 part Oleum Sesami, become withered yellow with the fried thing of boiling medicine of slow fire, medicine line of oils part after fried, with 3-4 layer filtered through gauze, following Cera Flava heat fused adds the medicine powder that (2) are organized with the medicine after the fusing from fire, constantly stirs, add (3) group medicine in the time of will becoming cream, stir evenly and promptly make Xiehuo Jiedu Shaoshang Gao.
The best component of the used Chinese medicine of Chinese medicine burn cream Xiehuo Jiedu Shaoshang Gao of the present invention:
(1) group is: 30 parts of 30 portions of Radix Ampelopsis of 15 parts of Radix Sophorae Tonkinensiss of 30 parts of Rhizoma Corydalis of 40 portions of Radix Ilicis Pubescentiss of Rhizoma Coptidis
20 parts of 20 parts of Radix Isatidiss of 30 parts of Cortex Dictamni of 20 portions of Cacumen Platycladis of 20 parts of Folium Hibisci Mutabiliss of Radix Sanguisorbae
25 parts of 20 parts of Fructus Forsythiaes of 40 parts of Pericarpium Papaveriss of 30 portions of Radix Arnebiae (Radix Lithospermi)s of 30 parts of Radix Paeoniae Rubra of Cortex Phellodendri
160 parts in 1500 parts of Cera Flavas of 10 parts of Oleum sesami of 30 parts of Squama Manis of Radix Trichosanthis.(2) group (powder) is.50 parts of Mirabilitum crystallinas, 50 parts in Gypsum Fibrosum, 30 parts of Semen Phaseolis, 30 parts of calamitas urinae hominises.(3) 2 parts of (powder) artificial Calculus Boviss of group, 6 parts of Borneolum Syntheticums
Later stage medication-the Shuangyou Shengji Shaoshang Gao of Chinese medicine burn cream of the present invention is with following medicine components (weight) processing and fabricating:
(1) carefully slightly branch 35-45 part (bright leaf 95-105 part), pappy shell 5-15 part Radix Angelicae Sinensis 15-25 part safflower 5-15 part root of Dahurain angelica 5-15 part Asian puccoon 15-25 part Radix Glycyrrhizae 15-25 part garden burnet 10-20 part radix ampelopsis 40-50 part golden cypress 10-20 part coptis 6-12 part rheum officinale 5-15 part radix paeoniae rubrathe 15-25 part sesame oil 1300-1700 part beeswax 140-180 part of group Cortex sophorae 25-35 part Chinese arborvitae root bark 25-35 part cacumen biotae 25-35 part willow leaf band. ( 2 ) organize mixing medicine oil ( medicine powder and oil ) : Radix Notoginseng 3-9 part is fried 48 parts of calamitas urinae hominis ( calcined ) 4-8 of Cortex Jujubae 5-15 part Olibanum 4-8 part Corium elephatis 5-15 part Myrrha part Gypsum Fibrosum Preparatum 10-20 part Sanguis Draxonis 4-8 part Pseudobulbus Bletillae ( Rhizoma Bletillae ) 25-35 part Plumbum preparatium 15-25 part chicken bone ( forging to getting final product in vain inside and outside leading to fire ) 10-25 part Ovum Gallus domesticus butter 45-55 part.
(3) group (powder) Borneolum Syntheticum 4-8 part
At first with the Corium elephatis of (2) group in the medicine with stir-baking with sand to isabelline becoming fragile, the each component medicine with (2) group grinds jointly then, cross the 100-120 mesh sieve and mix evenly with the Ovum Gallus domesticus butter, with Borneolum Syntheticum levigate the 100-120 order standby.Its processing technique is that (1) group medicine components was soaked 1-3 days in the Oleum sesami of 1300-1700 part, fry to withered yellow with slow fire, medicine line of oils part after fried, with 3-4 layer filtered through gauze, following Cera Flava heat fused, add the medicine powder and Ovum Gallus domesticus butter mixing medicine oil that (2) are organized from fire, add the Borneolum Syntheticum mixing when treating and make Shuangyou Shengji Shaoshang Gao one-tenth cream.
The optimal drug component of processing Shuangyou Shengji Shaoshang Gao of the present invention is:
(1) carefully branch 40 parts of (100 parts on bright leaf), 10 parts of Pericarpium Papaveriss, 20 parts of Radix Angelicae Sinensis, 10 parts on Flos Carthami, 10 parts of the Radixs Angelicae Dahuricae, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts in Radix Glycyrrhizae, 15 parts of Radix Sanguisorbaes, 45 parts of Radix Ampelopsis, 15 parts of Cortex Phellodendris, 9 parts of Rhizoma Coptidis, 10 parts of Radix Et Rhizoma Rhei, 20 parts of Radix Paeoniae Rubra, 1500 parts of Oleum sesami, Cera Flava 150-170 part slightly of 30 parts of Cortex sophoraes, 30 parts of Chinese arborvitae root barks, 30 parts of Cacumen Platycladis, Folium Salicis Babylonicae band in the group.(2) 6 parts of Radix Notoginsengs, 10 parts of Cortex Jujubae of stir-fry, 6 parts of Olibanums, 10 parts of Corium elephatiss, 6 parts of Myrrhas, 6 parts of calamitas urinae hominis(calcined), 15 parts of Gypsum Fibrosum Preparatum, 6 parts of Sanguis Draxonis, 30 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 20 parts of Plumbum preparatium, 15 parts of chicken bones, 50 parts in Ovum Gallus domesticus butter in the group.(3) the group Borneolum Syntheticum is 6 parts.
Burn Chinese medicinal ointment medication Xiehuo Jiedu Shaoshang Gao in early stage of the present invention and associated later stage medication " Shuangyou Shengji Shaoshang Gao " are used for the treatment of the burn overall process and have following effect:
1. pain relieving: pain relieving in 3-10 minute after the drug of topical application.2. few, soft, smooth, the good springiness of cicatrix after healing, rare contracture deformity.3. infection, external Chinese medicine resistance infection is strong, is that a large amount of clinical cases and zoopery confirm.The Chinese medicinal ointment pus secretions of changing dressings increases thereupon, the lysozyme content height, and macrophage quantity is many, and phagocytic function is active, has strengthened the defence capability of human body, thereby has strengthened resistance infection.4. promote the recovery that the burned skin stasis of blood stagnates and organizes,, increase regional flow, promote the formation of wound surface regenerate hair blood vessel, thereby therefore the recovery that impels the burned skin stasis of blood to stagnate and organize need not skin-grafting because this medicine has reduced the viscosity of blood.With the fire victim that Chinese medicinal ointment of the present invention is caused injury through the thousands of routine a variety of causes of external application for curing, cure rate 96.4%, aggregate efficiency are 100%.The healing in about 8 days of shallow II degree burn, deep ii degree burn healed about 18 days, the healing in about 35 days of shallow III degree burn, dark muscle healing in undisguised about 60 days.Medication in early stage of the present invention " Xiehuo Jiedu Shaoshang Gao " and later stage medication " Shuangyou Shengji Shaoshang Gao " also can be used separately according to fire victim's degree of burning.Can cure with " Xiehuo Jiedu Shaoshang Gao " as superficial burns patient I, II degree.
Example 1:
Take by weighing Rhizoma Coptidis 40g (smashing); Radix Ilicis Pubescentis 30; Rhizoma Corydalis 15g; Radix Sophorae Tonkinensis 30g; Radix Ampelopsis 30g; Radix Sanguisorbae 20g; Folium Hibisci Mutabilis 20g; Cacumen Platycladi 30g; Cortex Dictamni 20g; Radix Isatidis 20g; Cortex Phellodendri 30g; Radix Paeoniae Rubra 30g; Radix Arnebiae (Radix Lithospermi) 40g; Pericarpium Papaveris 20g; Fructus Forsythiae 25g; Radix Trichosanthis 30g; Squama Manis 10g; putting into the 1500g Oleum sesami together soaks and to fry in shallow oil to withered yellow with slow fire is fried in 2 days; remove medicinal residues with four layers of filtered through gauze; following Cera Flava 160g; the fusing of getting angry again; change turning off stove and add the Mirabilitum crystallina 50g that has ground into fine powder (crossing 120 mesh sieves) in advance; Gypsum Fibrosum 50g; Semen Phaseoli 30g; calamitas urinae hominis 30g mixed dust formulation; constantly stir; in case the heavy medicated powder of matter sinks to the bottom; it is inhomogeneous that medicine is mixed; add the artificial Calculus Bovis 2g that has ground to form fine powder when treating with one-tenth cream; Borneolum Syntheticum 6g restir is promptly made after stirring evenly " Xiehuo Jiedu Shaoshang Gao ".
Take by weighing Cortex sophorae 30g, Chinese arborvitae root bark 30g, Cacumen Platycladi 30g, the Folium Salicis Babylonicae band carefully slightly the branch (doing) 40g, Pericarpium Papaveris 10g, Radix Angelicae Sinensis 20g, Flos Carthami 100g, Radix Angelicae Dahuricae 10g, Radix Arnebiae (Radix Lithospermi) 20g, Radix Glycyrrhizae 20g, Radix Sanguisorbae 15g, Radix Ampelopsis 45g, Cortex Phellodendri 15g, Rhizoma Coptidis 9g, Radix Et Rhizoma Rhei 10g, Radix Paeoniae Rubra 20g puts into Oleum sesami 1500g and soaked 2 days, fry in shallow oil to withered yellow with slow fire is fried, remove slag with four layers of filtered through gauze, following Cera Flava 160g, the fusing of getting angry again, change turning off stove and add the Radix Notoginseng 6g that has ground into fine powder (120 order) in advance, Corium elephatis (crisp) 10g through stir-baking with sand, Olibanum, each 6g of Myrrha, calamitas urinae hominis(calcined) 6g, Gypsum Fibrosum Preparatum 15g, Sanguis Draxonis 6g, Pseudobulbus Bletillae (Rhizoma Bletillae) 30g, Plumbum preparatium 20g, the mixed oil liquid that chicken bone (forging to inside and outside logical white with fire) 15g and Ovum Gallus domesticus butter 50g mix thoroughly, constantly stir, it is stirred evenly, add when treating and make later stage medication " two oily granulation promoting skin cream " after borneol powder stirs evenly one-tenth cream.
Example 2:
Take by weighing by example 1 and to deduct Radix Trichosanthis, Semen Phaseoli, Squama Manis in the medicine components, add and deduct Oleum sesami 250g, vaseline 1250g, the fried thing of boiling medicine, other technologies can make the Chinese medicine burn cream of using I, II degree superficial burns wound surface with example 1.
Be used for III degree eschar wound surface eliminating fire and detoxication, the profit Jiao take off corruption, making substrate with the Oleum Sesami Cera Flava is good with example 1 medicine component.

Claims (2)

1. Xiehuo Jiedu Shaoshang Gao; It is characterized in that making described medicine components weight: (1) coptis 10-50 part ilex pubescens 25-35 part corydalis tuber 10-25 part subprostrate sophora 25-35 part radix ampelopsis 25-35 part garden burnet 15-25 part FOLIUM HIBISCI MUTABILIS 15-25 part cacumen biotae 25-35 part root bark of shaggy-fruited dittany 15-25 part isatis root 15-25 part golden cypress 25-35 part radix paeoniae rubrathe 25-35 part Asian puccoon 35-45 part pappy shell 15-25 part capsule of weeping forsythia 20-30 part root of Chinese trichosanthes 0-35 part first pearl 0-15 part beeswax 150-170 part vaseline 0-1250 part sesame oil 250-1700 part (2) group pulvis with following medicine components processing technology
Mirabilitum crystallina 30-55 part Gypsum Fibrosum 30-55 part
Semen Phaseoli 0-35 part calamitas urinae hominis's 25-35 part (3) group powder
The described processing technique of artificial Calculus Bovis 1.5-2.5 part Borneolum Syntheticum 4-8 part is that (1) medicine components was soaked 1-3 days in 250-1400 part Oleum sesami; the fried thing of boiling medicine of slow fire becomes withered yellow; use filtered through gauze; following Cera Flava heat fused; add (2) group medicine from fire; constantly stir, add (3) group medicine in the time of will becoming cream, stir evenly, also can be with (1) medicine fried frying in shallow oil in Oleum sesami and vaseline miscella.
2; ointment for treating burn as claimed in claim 1; it is characterized in that described medicine components weight is 40 parts of Rhizoma Coptidis in (1) group; 30 parts of Radix Ilicis Pubescentiss; 15 parts of Rhizoma Corydalis; 30 parts of Radix Sophorae Tonkinensiss; 30 parts of Radix Ampelopsis; 20 parts of Radix Sanguisorbaes; 20 parts of Folium Hibisci Mutabiliss; 30 parts of Cacumen Platycladis; 20 parts of Cortex Dictamni; 20 parts of Radix Isatidiss; 30 parts of Cortex Phellodendris; 30 parts of Radix Paeoniae Rubra; 40 parts of Radix Arnebiae (Radix Lithospermi)s; 20 parts of Pericarpium Papaveriss; 25 parts of Fructus Forsythiaes; 30 parts of Radix Trichosanthis; 10 parts of Squama Manis; 1500 parts of Oleum sesami; 160 parts in Cera Flava; (2) 50 parts of Mirabilitum crystallinas in the group; 50 parts in Gypsum Fibrosum; 30 parts of Semen Phaseolis; 30 parts of calamitas urinae hominises, the artificial Calculus Bovis is 2 parts in (3) group; 6 parts of Borneolum Syntheticums.
CN93106813A 1993-06-10 1993-06-10 Traditional Chinese medicine ointment for curing burns and preparing method Expired - Fee Related CN1053573C (en)

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KR100494348B1 (en) * 2002-07-23 2005-06-10 남종현 Drug for treatment of a burn and preparing process thereof
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CN100381143C (en) * 2005-12-13 2008-04-16 上海方心科技研究所 Chinese-medicine cataplasma for treating cervical vertebra disease and preparing method
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CN101214333B (en) * 2007-12-27 2010-06-23 逯萍 Medicament for treating empyrosis
CN101342316B (en) * 2008-08-13 2011-01-26 赵建良 Traditional Chinese medicine externally used combined formulation for treating burn
CN101507785B (en) * 2009-03-31 2012-07-11 王克俭 Ointment for treating psoriasis
CN102579820A (en) * 2011-01-07 2012-07-18 韦军来 Ointment for treating burns and scalds and preparation method of ointment
CN102228554B (en) * 2011-07-02 2013-04-10 李亚 Medicament for treating empyrosis and scalding and preparation method thereof
CN102284011A (en) * 2011-07-29 2011-12-21 尉文胜 Chinese medicinal ointment for treating burn
CN102302677B (en) * 2011-08-29 2013-04-17 陈德素 Burn and scald liquid, burn and scald ointment, and preparation method thereof
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CN103316064A (en) * 2013-06-14 2013-09-25 周建和 Liquid medicine for treating scalds and preparation method thereof
CN103705749B (en) * 2014-01-02 2016-07-06 深圳意达凯生物科技有限公司 A kind of burn and scald spray
CN106038852A (en) * 2016-05-31 2016-10-26 周耀林 Pharmaceutical composition for treating burns and scalds and preparation method and application thereof
CN115054639A (en) * 2022-07-11 2022-09-16 侯成卉 Formula and preparation method of traditional Chinese medicine ointment for treating scalds

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