CN105352891B - Urine desiccation analysis method and device based on beam splitter - Google Patents

Urine desiccation analysis method and device based on beam splitter Download PDF

Info

Publication number
CN105352891B
CN105352891B CN201510933219.1A CN201510933219A CN105352891B CN 105352891 B CN105352891 B CN 105352891B CN 201510933219 A CN201510933219 A CN 201510933219A CN 105352891 B CN105352891 B CN 105352891B
Authority
CN
China
Prior art keywords
test
control unit
respective items
unit
color sensor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201510933219.1A
Other languages
Chinese (zh)
Other versions
CN105352891A (en
Inventor
熊兴良
陈龙聪
高斌
江奇锋
邓世雄
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chongqing Medical University
Original Assignee
Chongqing Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chongqing Medical University filed Critical Chongqing Medical University
Priority to CN201510933219.1A priority Critical patent/CN105352891B/en
Publication of CN105352891A publication Critical patent/CN105352891A/en
Application granted granted Critical
Publication of CN105352891B publication Critical patent/CN105352891B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/255Details, e.g. use of specially adapted sources, lighting or optical systems

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention discloses a kind of urine desiccation analysis method based on beam splitter and device, method and step system initialization;Each empirical equation of test item, the sxemiquantitative section of each respective items and intensity of illumination needed for detection in being analyzed by the touch display unit input urine desiccation in control module;Light intensity regulating;Test strips correspond to the R, G, B component and ambient temperature measurement of color lump;Rule of thumb formula is calculated the reflectivity of corresponding test strips, and according to respective items sxemiquantitative section, draws the semidefinite value of test strips.Its remarkable result is:Urine Analyzer volume can be reduced, improves the uniformity, stability and measurement accuracy of Urine Analyzer;The incident light and reflected light of detection light on one wire, can effectively reduce the influence of ambient light, and reduce the influence of distance between test strips and detection means well;Setting light intensity can be automatically adjusted, while detection light intensity imbalance etc. can be sent to influence the warning message of testing result.

Description

Urine desiccation analysis method and device based on beam splitter
Technical field
The present invention relates to the routine urinalysis detection technique field of biomedical sector, is that one kind is based on beam splitting specifically The urine desiccation analysis method and device of mirror.
Background technology
Urine Analyzer is made up of mechanical system (transmission), optical system and control circuit system three parts, wherein light System is the key component of instrument, mainly realizes the collection of color.Its method is mainly by the reaction of optical illumination to test paper Area surface produces reflected light, and the reaction color of the intensity of reflected light and each test event is into relevant, and at present using oblique Incident method, this causes test strips from a distance from light source and incident direction etc. can produce large effect to test result, main Showing influences the uniformity and measurement accuracy of test result.
Although there is document report to reduce test knot to a certain extent using the method for half-reflecting half mirror and T-shaped smooth Down lamp The uniformity of fruit and the accuracy for improving measurement to a certain extent, but in practice due to the change of irradiation light intensity, can be to measurement As a result obvious change is produced;Also take and often realize calibration using white block, large effect otherwise can be produced to measurement result; If in addition, irradiating light intensity in measurement process, there occurs larger change, equipment can not also detect, it is impossible to sends alarm or wrong By mistake.
The content of the invention
In view of the shortcomings of the prior art, it is an object of the invention to provide a kind of urine desiccation analysis method based on beam splitter And device, it can be advantageous to reduce the volume of urine desiccation analysis detector or device, reduce test strips from a distance from light source pairs The influence of test result, it is possible to increase measurement accuracy, it is easier to minimize, commercialization.
To reach above-mentioned purpose, the technical solution adopted by the present invention is as follows:
A kind of urine desiccation analysis method based on beam splitter, its key are to follow the steps below:
Step 1:System initialization;
Step 2:The warp of each test item in urine desiccation analysis is inputted by the touch display unit in control module Test formula, the sxemiquantitative section of each respective items and intensity of illumination needed for detection;
Step 3:The control module control composite light source sends the complex light needed for detection, and causes light beam by being located at After beam splitter transmission in the flat cylinder of cross, the first color sensor and the second color sensor are at normal work shape State;
Step 4:Test strips are placed on test paper platform, the control module Driving Stepping Motor rotates, and controls test paper platform On test strips by the detection zone below the flat cylinder of the cross;
Step 5:The control module obtains the corresponding color lump of test strips from the first color sensor and the second color sensor R, G, B component, and environment temperature is detected by temperature measurement unit;
Step 6:R, G, B component and the environment temperature that the control module obtains step 5 substitute into the empirical equation, meter Calculate and draw the reflectivity of corresponding test strips, and according to respective items sxemiquantitative section, draw the semidefinite value of test strips.
Further, empirical equation is described in step 2:
Y*=c0+c1DR+c2(DR)2+c3DG+c4(DG)2+c5DB+c6(DB)2+c7T+c8T2
In formula, y* represents the reflectivity of the fitting of respective items;c0Represent the Fitting Calculation coefficient;c1Represent the red of respective items The design factor of the first power of component fitting, c2Represent the design factor of the quadratic power of the red component fitting of respective items, DRRepresent The value of the respective items red component of measure;c3Represent the design factor of the first power of the green component fitting of respective items, c4Expression pair Answer the design factor for the quadratic power that the green component of item is fitted, DGRepresent the value of the respective items green component of measure;c5Represent corresponding The design factor of the first power of the blue component fitting of item, c6Represent the calculating system of the quadratic power of the blue component fitting of respective items Number, DBRepresent the value of the respective items blue component of measure;c7Represent the design factor of the first power of the temperature foh of respective items, c8 The design factor of the quadratic power of the temperature foh of respective items is represented, T represents ambient temperature value during measurement.
Further, the design factor described in step 2 in empirical equation uses PLS, and repeated detection is obtained R, G, B component and the measurement temperature of the corresponding color lump taken carry out quadratic term fitting and drawn.
Further, the obtaining step of design factor is as follows in empirical equation described in step 2:
Step 2-1:Multiple temperature spots in the range of 5 DEG C~35 DEG C of selection, under each temperature spot environment, phase is added to by urine Answer in test strips (1) after 1 minute, tried using control liquid I, II, III of existing instrument test various concentrations and actual urine The reflectivity y of a reagent area in paper slip (1)m, wherein m is the order for representing test;
Step 2-2:R, G, B color component value and temperature value of corresponding indicator paper block are obtained, and it is former according to PLS Reason, when obtaining the m times test, the detection parameters x in mentioned reagent area0m,x1m,x2m,x3m,x4m,x5m,x6m,x7m,x8m,
Wherein, x0m=1;x1m=DR,mFor the red component of the m times test;x2m=(DR,m)2For the red of the m times test Square of component;x3m=DG,mFor the green component of the m times test;x4m=(DG,m)2For the m times test green component it is flat Side;x5m=DB,mFor the blue component of the m times test;x6m=(DB,m)2For square of the blue component of the m times test;x7m=T For the temperature value degree of the m times test;x8m=T2For square of the temperature value degree of the m times test;
Step 2-3:Coefficient formulas is obtained according to the detection parameters of acquisition And the coefficient c in the empirical equation is calculated according to the formula0、c1、c2、c3、c4、c5、c6、c7、c8, k=0~8.
The invention also discloses a kind of device for carrying out the above-mentioned urine desiccation analysis method based on beam splitter, including for Place the test paper platform of test strips, stepper motor, the cross above the test paper platform for driving the test paper platform to move Flat cylinder and control module, beam splitter is installed in the center of the flat cylinder of the cross, in the left and right of the flat cylinder of the cross Both sides are separately installed with the first color sensor and composite light source, and the second color sensing is provided with the top of the flat cylinder of the cross Device;
The control module includes microprocessor control unit, is connected with the microprocessor control unit touch aobvious Show unit, color acquisition unit, step motor control unit, temperature detecting unit, intensity control unit and wireless receiving and dispatching list Member, wherein the color acquisition unit electrically connects with first color sensor, the second color sensor respectively, the stepping Motor control unit is electrically connected with the stepper motor, and the intensity control unit electrically connects with the composite light source;
The microprocessor control unit is used for the intensity control for realizing composite light source and from the first color sensor and the Second colors sensor, temperature detecting unit read data, the reflectivity of test strips are calculated according to corresponding data, further according to semidefinite Amount section draws the semidefinite value of test strips, and shows or uploaded by wireless transmit/receive units on touch display unit;Institute State color acquisition unit to be used to read information from the first color sensor and the second color sensor, realize R, B, G of color lump The acquisition of value;The step motor control unit is used for the drive control for realizing stepper motor;The temperature detecting unit is used for Detection to environment temperature;The intensity control unit is used for the intensity of illumination regulation for realizing composite light source;The wireless receiving and dispatching Unit is used for the communication with external equipment, realizes and carries out data interchange with external equipment.
Further, the control signal input of the intensity control unit directly connects with the microprocessor control unit Connect, the signal output part of the intensity control unit is connected by A/D modular converters with the microprocessor control unit, the temperature Degree measuring unit realizes information exchange also by the A/D modular converters and microprocessor control unit.
Further, memory cell, data-printing unit and limit are also associated with the microprocessor control unit Position detection unit, wherein the spacing detection unit is used to detect the stroke of test paper platform, and sends information and pass through micro- place Manage the operating of device control unit control stepper motor.
Further, the touch display unit uses touch LCD liquid crystal display screen.
Further, the color sensor can use TCS3103 high accuracy color sensors.
In the present invention, composite light source provides the adjustable light of brightness of red, green and blue three primary colours;Beam splitter mainly has Two aspects act on, and are on the one hand to realize the light of composite light source transmitting reflexing to test strips, and the light reflected through test strips is saturating To color sensor, the rgb value of color and light intensity value are converted to corresponding digital value by color sensor, further to locate Reason;On the other hand it is to realize a part of light of composite light source transmitting shining directly into color sensor, detects three kinds of color of light Light intensity, if light intensity is changed, control module obtains specific situation of change, microprocessor by reading color sensor The brightness of corresponding composite light source is automatically adjusted under program control, is value set in advance so as to keep irradiating light intensity, and then It is further ensured that precision, the stability and uniformity of measurement of measurement result.Two color sensors one are used to detect incidence The size of light intensity, another is used to detect the light intensity magnitude through tested indicator paper block reflection;The flat cylinder of cross is mainly used in fixing two Individual color sensor and beam splitter, while reduce influence of the external environmental light to sensor, to improve the essence of last testing result Degree.
In actual applications, the empirical equation of each test item, then the RGB component by acquisition are obtained according to existing instrument first The reflectivity of corresponding indicator paper block is calculated using the empirical equation of each test item with environment temperature, then according to the sxemiquantitative of setting Section obtains the semidefinite value of corresponding entry, i.e. end product.On the one hand can greatly reduce test strips from a distance from detection module, Illumination etc. greatly improves the uniformity, stability and measurement accuracy of Urine Analyzer to being influenceed caused by test result meeting;In addition On the one hand the change of energy automatic detection irradiation light intensity, and the regulation of light intensity can be realized automatically, it can further improve Urine Analyzer Measurement accuracy.
The present invention remarkable result be:
A) Urine Analyzer volume can be reduced, improves the uniformity, stability and measurement accuracy of Urine Analyzer;
B) incident light of detection light and reflected light on one wire, effectively reduce the influence of ambient light, and subtract well The small influence of distance between test strips and detection means;
C) setting light intensity can be automatically adjusted so that the light intensity of detection keeps the high-precision constant intensity of setting, while can send out Going out to detect light intensity imbalance etc. influences the warning message of testing result.
Brief description of the drawings
Fig. 1 is flow chart of the method for the present invention;
Fig. 2 is the structural representation of the present invention;
Fig. 3 is the circuit structure block diagram of the control module.
Embodiment
The embodiment and operation principle of the present invention are described in further detail below in conjunction with the accompanying drawings.
As shown in figure 1, a kind of urine desiccation analysis method based on beam splitter, is comprised the following steps that:
Step 1:System initialization;
Step 2:The warp of each test item in urine desiccation analysis is inputted by the touch display unit in control module 5 Test formula, the sxemiquantitative section of each respective items and intensity of illumination needed for detection;
The empirical equation is:
Y*=c0+c1DR+c2(DR)2+c3DG+c4(DG)2+c5DB+c6(DB)2+c7T+c8T2,
In formula, y* represents the reflectivity of the fitting of respective items;c0Represent the Fitting Calculation coefficient;c1Represent the red of respective items The design factor of the first power of component fitting, c2Represent the design factor of the quadratic power of the red component fitting of respective items, DRRepresent The value of the respective items red component of measure;c3Represent the design factor of the first power of the green component fitting of respective items, c4Expression pair Answer the design factor for the quadratic power that the green component of item is fitted, DGRepresent the value of the respective items green component of measure;c5Represent corresponding The design factor of the first power of the blue component fitting of item, c6Represent the calculating system of the quadratic power of the blue component fitting of respective items Number, DBRepresent the value of the respective items blue component of measure;c7Represent the design factor of the first power of the temperature foh of respective items, c8 The design factor of the quadratic power of the temperature foh of respective items is represented, T represents ambient temperature value during measurement.
Design factor in formula uses PLS, R, G, the B component of the corresponding color lump obtained to repeated detection And measurement temperature carries out quadratic term fitting and drawn.Step is as follows:
Step 2-1:It is optionally about in the environment of 5 DEG C, 10 DEG C, 15 DEG C, 20 DEG C, 25 DEG C, 30 DEG C, 35 DEG C, urine is added to On corresponding indicator paper block after 1 minute, using the urinalysis instrument of existing high reliability test various concentrations control liquid I, The reflectivity y of a reagent area in II, III and actual urine test strips 1m, wherein m is the order for representing test;Utilize simultaneously The device of this proposition obtains R, G, B color component value and temperature value of corresponding indicator paper block.
Step 2-2:Use ymRepresent the reflectivity of the m times actually measured test, ym* the reflection of the m times test fitting is represented Rate, then its poor δm=| ym-ym* |, wherein y* is represented by:
Wherein, x0m=1;x1m=DR,mFor the red component of the m times test;x2m=(DR,m)2For the red of the m times test Square of component;x3m=DG,mFor the green component of the m times test;x4m=(DG,m)2For the m times test green component it is flat Side;x5m=DB,mFor the blue component of the m times test;x6m=(DB,m)2For square of the blue component of the m times test;x7m=T For the temperature value degree of the m times test;x8m=T2For square of the temperature value degree of the m times test;
Step 2-3:Coefficient formulas is obtained according to the detection parameters of acquisition And the coefficient c in the empirical equation is calculated according to the formula0、c1、c2、c3、c4、c5、c6、c7、c8, k=0~8.
It is determined that during each coefficient, the main principle for using least square method multiple regression, actually measured is anti- Penetrate rate to be represented with y, share N (N>20) it is individual, use ymRepresent the reflectivity of the m times actually measured test, ymThe plan of * the m times test The reflectivity of conjunction, then its poor δm=| ym-ym* |, to be caused according to the principle of least square method Minimum, i.e.,It is minimum.Then have:
I.e.:Have after arrangement:
Wherein (k=0, L, 8), because
Institute
It can be arranged with the formula and be:Also can be write as:
The data measured to each single item bring above-mentioned 9 equations into, solve c0,c1,…,c7,c8, then Multivariate Quasi can be obtained Close function:
Y*=c0+c1DR+c2(DR)2+c3DG+c4(DG)2+c5DB+c6(DB)2+c7T+c8T2
Step 3:Microprocessor control unit controls composite light source to send required intensity of illumination by intensity control unit Light, and cause light beam after the beam splitter 6 in the flat cylinder 4 of cross transmits, the first color sensor 7 and the second color pass Sensor 9 is at normal operating conditions;
Step 4:Test strips 1 are placed on test paper platform 2, the microprocessor control unit passes through step motor control list First Driving Stepping Motor 3 rotates, and the test strips 1 on control test paper platform 2 are by the detection zone below the flat cylinder 4 of the cross;
Step 5:The microprocessor control unit is by color acquisition unit from the first color sensor 7 and the second color Sensor 9 obtains test strips and corresponds to R, G of color lump, B component, and detects environment temperature by temperature measurement unit;
Step 6:R, G, B component and the environment temperature that the microprocessor control unit obtains step 5 substitute into the warp Formula is tested, is calculated the reflectivity of corresponding test strips 1, and according to respective items sxemiquantitative section, draws the semidefinite of test strips 1 Value.
Creatinine CRE semidefinite value section, as shown in table 1.If rule of thumb formula calculates the anti-of this in practice It is 70% to penetrate rate, then software can show that its semi-quantitative results is according to table 1:TRACE or use+- represent to handle.
The creatinine CRE of table 1 semidefinite value section and semidefinite value
If need to export as reflectivity, the reflectivity calculated is exported, if the rgb value then rgb value currently to determine.If half Quantitative values then export relatively after semidefinite value.
Referring to accompanying drawing 2, based on the above-mentioned urine desiccation analysis method based on beam splitter, the present invention, which proposes, carries out above-mentioned side The device of method, including for place test strips 1 test paper platform 2, for drive the test paper platform 2 move stepper motor 3, positioned at institute The flat cylinder 4 of cross and control module 5 of the top of test paper platform 2 are stated, beam splitting is installed in the center of the flat cylinder 4 of the cross Mirror 6, the first color sensor 7 and composite light source 8 are separately installed with the left and right sides of the flat cylinder 4 of the cross, in the cross The top of flat cylinder 4 is provided with the second color sensor 9.
As shown in figure 3, the control module includes microprocessor control unit, connected in the microprocessor control unit Have touch display unit, color acquisition unit, step motor control unit, temperature detecting unit, intensity control unit and Wireless transmit/receive units, wherein the color acquisition unit is electric with first color sensor 7, the second color sensor 9 respectively Connection, the step motor control unit are electrically connected with the stepper motor 3, the intensity control unit and the complex light Source 8 electrically connects;
The microprocessor control unit be used for the intensity control for realizing composite light source 8 and from the first color sensor 7 with Second color sensor 9, temperature detecting unit read data, and the reflectivity of test strips 1 is calculated according to corresponding data, further according to Sxemiquantitative section draws the semidefinite value of test strips 1, and is shown or by wireless transmit/receive units on touch display unit Pass;The color acquisition unit is used to read information from the first color sensor 7 and the second color sensor 9, realizes color lump R, B, G value acquisition;The step motor control unit is used for the drive control for realizing stepper motor 3;The temperature detection Unit is used for the detection to environment temperature;The intensity control unit is used for the intensity of illumination regulation for realizing composite light source 8;It is described Wireless transmit/receive units are used for the communication with external equipment, realize and carry out data interchange with external equipment.
From figure 3, it can be seen that the control signal input of the intensity control unit and microprocessor control are single Member is directly connected to, and the signal output part of the intensity control unit is connected by A/D modular converters and the microprocessor control unit Connect, the temperature measurement unit realizes information exchange also by the A/D modular converters and microprocessor control unit.
It can also be seen that being also associated with memory cell, data-printing list in the microprocessor control unit from Fig. 3 First and spacing detection unit, wherein, the data-printing unit is used to be printed detection data, and the spacing detection is single Member is used to detect the stroke of test paper platform 2, and sends the fortune that information controls stepper motor 3 by microprocessor control unit Turn.
In this example, preferably described touch display unit uses touch LCD liquid crystal display screen.
In this example, the preferably described color sensor 9 of first color sensor 7 and second uses TCS3103 high accuracy colors Sensor.
In this example, for the ease of centralized Control, the microprocessor control unit, touch display unit, color acquisition Unit, step motor control unit, temperature detecting unit, intensity control unit and wireless transmit/receive units etc. are by power supply unit It is powered.
The present invention obtains the empirical equation of each test item, then RGB component and environment by acquisition according to existing instrument first Temperature calculates the reflectivity of corresponding indicator paper block using the empirical equation of each test item, is then obtained according to the sxemiquantitative section of setting To the semidefinite value of corresponding entry, i.e. end product.On the one hand greatly reduce test strips from a distance from detection module, illumination etc. On being influenceed caused by test result meeting, the uniformity, stability and measurement accuracy of Urine Analyzer are improved;Still further aspect energy Automatic detection irradiates the change of light intensity, and realizes the regulation of light intensity automatically, and the measurement for further increasing Urine Analyzer is accurate True property.

Claims (8)

1. a kind of urine desiccation analysis method based on beam splitter, it is characterised in that follow the steps below:
Step 1:System initialization;
Step 2:The experience of each test item in urine desiccation analysis is inputted by the touch display unit in control module (5) Formula, the sxemiquantitative section of each respective items and intensity of illumination needed for detection;
Empirical equation is described in step 2:
Y*=c0+c1DR+c2(DR)2+c3DG+c4(DG)2+c5DB+c6(DB)2+c7T+c8T2
In formula, y* represents the reflectivity of the fitting of respective items;c0Represent the Fitting Calculation coefficient;c1Represent the red component of respective items The design factor of the first power of fitting, c2Represent the design factor of the quadratic power of the red component fitting of respective items, DRRepresent measure Respective items red component value;c3Represent the design factor of the first power of the green component fitting of respective items, c4Represent respective items Green component fitting quadratic power design factor, DGRepresent the value of the respective items green component of measure;c5Represent respective items The design factor of the first power of blue component fitting, c6Represent the design factor of the quadratic power of the blue component fitting of respective items, DB Represent the value of the respective items blue component of measure;c7Represent the design factor of the first power of the temperature foh of respective items, c8Expression pair The design factor of the quadratic power of the temperature foh of item is answered, T represents ambient temperature value during measurement;
Step 3:Control module (5) the control composite light source (8) sends the complex light needed for detection, and causes light beam by position After beam splitter (6) transmission in the flat cylinder of cross (4), the first color sensor (7) can with the second color sensor (9) In normal operating conditions;
Step 4:Test strips (1) are placed on test paper platform (2), control module (5) Driving Stepping Motor (3) rotates, control Test strips (1) on test paper platform (2) processed are by the detection zone below the flat cylinder of the cross (4);
Step 5:The control module (5) obtains test strips (1) from the first color sensor (7) and the second color sensor (9) R, G, the B component of corresponding color lump, and environment temperature is detected by temperature measurement unit;
Step 6:R, G, B component and the environment temperature that the control module (5) obtains step 5 substitute into the empirical equation, meter Calculation draws the reflectivity of corresponding test strips (1), and according to respective items sxemiquantitative section, draws the semidefinite value of test strips (1).
2. the urine desiccation analysis method according to claim 1 based on beam splitter, it is characterised in that:Described in step 2 Design factor in empirical equation uses PLS, R, G, B component and the survey of the corresponding color lump obtained to repeated detection Amount temperature carries out quadratic term fitting and drawn.
3. the urine desiccation analysis method according to claim 2 based on beam splitter, it is characterised in that:Described in step 2 The obtaining step of design factor is as follows in empirical equation:
Step 2-1:Multiple temperature spots in the range of 5 DEG C~35 DEG C of selection, under each temperature spot environment, urine are added to and mutually taken an entrance examination On paper slip (1) after 1 minute, control liquid I, II, III and actual urine test strips using existing instrument test various concentrations (1) the reflectivity y of a reagent area inm, wherein m is the order for representing test;
Step 2-2:R, G, B color component value and temperature value of corresponding indicator paper block are obtained, and according to PLS principle, is asked When going out the m times test, the detection parameters x in mentioned reagent area0m,x1m,x2m,x3m,x4m,x5m,x6m,x7m,x8m,
Wherein, x0m=1;x1m=DR,mFor the red component of the m times test;x2m=(DR,m)2For the red component of the m times test Square;x3m=DG,mFor the green component of the m times test;x4m=(DG,m)2For square of the green component of the m times test;x5m= DB,mFor the blue component of the m times test;x6m=(DB,m)2For square of the blue component of the m times test;x7m=T is the m times survey The temperature value degree of examination;x8m=T2For square of the temperature value degree of the m times test;
Step 2-3:Coefficient formulas is obtained according to the detection parameters of acquisition And the coefficient c in the empirical equation is calculated according to the formula0、c1、c2、c3、c4、c5、c6、c7、c8, k=0~8.
A kind of 4. device for carrying out the urine desiccation analysis method based on beam splitter as claimed in claim 1, it is characterised in that: Including the test paper platform (2) for placing test strips (1), for drive the test paper platform (2) move stepper motor (3), positioned at institute The flat cylinder of cross (4) and control module (5) above test paper platform (2) are stated, is pacified in the center of the flat cylinder of the cross (4) Equipped with beam splitter (6), the first color sensor (7) and complex light are separately installed with left and right sides of the flat cylinder of the cross (4) Source (8), the second color sensor (9) is installed at the top of the flat cylinder of the cross (4);
The control module includes microprocessor control unit, and it is single that touch display is connected with the microprocessor control unit Member, color acquisition unit, step motor control unit, temperature detecting unit, intensity control unit and wireless transmit/receive units, its Described in color acquisition unit electrically connected respectively with first color sensor (7), the second color sensor (9), the step Stepper motor control unit is electrically connected with the stepper motor (3), and the intensity control unit is electrically connected with the composite light source (8) Connect;
The microprocessor control unit be used for realize composite light source (8) intensity control and from the first color sensor (7) with Second color sensor (9), temperature detecting unit read data, and the reflectivity of test strips (1) is calculated according to corresponding data, then The semidefinite value of test strips (1) is drawn according to sxemiquantitative section, and is shown on touch display unit or passes through wireless receiving and dispatching Unit uploads;The color acquisition unit, which is used to read from the first color sensor (7) and the second color sensor (9), to be believed Breath, realizes the acquisition of R, B, G value of color lump;The step motor control unit is used for the drive control for realizing stepper motor (3); The temperature detecting unit is used for the detection to environment temperature;The intensity control unit is used for the light for realizing composite light source (8) According to intensity adjustment;The wireless transmit/receive units are used for the communication with external equipment, realize and carry out data interchange with external equipment.
5. the device of the urine desiccation analysis method according to claim 4 based on beam splitter, it is characterised in that:The light The control signal input of strong control unit is directly connected to the microprocessor control unit, the signal of the intensity control unit Output end is connected by A/D modular converters with the microprocessor control unit, and the temperature measurement unit turns also by the A/D Mold changing block realizes information exchange with microprocessor control unit.
6. the device of the urine desiccation analysis method according to claim 4 based on beam splitter, it is characterised in that:Described Memory cell, data-printing unit and spacing detection unit are also associated with microprocessor control unit, wherein described spacing Detection unit is used to detect the stroke of test paper platform (2), and sends information and control stepping by microprocessor control unit The operating of motor (3).
7. the device of the urine desiccation analysis method according to claim 4 based on beam splitter, it is characterised in that:It is described to touch Touch formula display unit and use touch LCD liquid crystal display screen.
8. the device of the urine desiccation analysis method according to claim 4 based on beam splitter, it is characterised in that:Described One color sensor (7) can use TCS3103 high accuracy color sensors with the second color sensor (9).
CN201510933219.1A 2015-12-15 2015-12-15 Urine desiccation analysis method and device based on beam splitter Expired - Fee Related CN105352891B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510933219.1A CN105352891B (en) 2015-12-15 2015-12-15 Urine desiccation analysis method and device based on beam splitter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510933219.1A CN105352891B (en) 2015-12-15 2015-12-15 Urine desiccation analysis method and device based on beam splitter

Publications (2)

Publication Number Publication Date
CN105352891A CN105352891A (en) 2016-02-24
CN105352891B true CN105352891B (en) 2018-02-16

Family

ID=55328897

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510933219.1A Expired - Fee Related CN105352891B (en) 2015-12-15 2015-12-15 Urine desiccation analysis method and device based on beam splitter

Country Status (1)

Country Link
CN (1) CN105352891B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107561076A (en) * 2017-07-28 2018-01-09 武汉市安友泽瑞科技有限公司 The low cost optical electricity detecting system and method judged for the line color depth
CN107860766A (en) * 2017-10-24 2018-03-30 吉林大学 Dry chemical method accurate detection device and method based on color sensor

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202002731U (en) * 2011-04-12 2011-10-05 重庆医科大学 Semi-reflecting and semi-transmitting mirror-based color collector for urine analyzer
CN202949130U (en) * 2012-11-22 2013-05-22 北京工业大学 Real-time measurement and control system for laser power
CN103399006A (en) * 2013-07-29 2013-11-20 重庆医科大学 Color RGB (red, green and blue)-component-based urine analysis device and processing method thereof
CN104266584A (en) * 2014-10-16 2015-01-07 北京理工大学 Automatic feedback light intensity adjusting device for laser self-mixing interference system
CN104792705A (en) * 2015-04-16 2015-07-22 西安交通大学 Laser power fluctuation monitoring and compensating device and method for photoacoustic spectrum measurement
CN105136431A (en) * 2015-08-24 2015-12-09 西安电子科技大学 Measurement system for optical element transmittance and reflectance based on acousto-optic modulation

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202002731U (en) * 2011-04-12 2011-10-05 重庆医科大学 Semi-reflecting and semi-transmitting mirror-based color collector for urine analyzer
CN202949130U (en) * 2012-11-22 2013-05-22 北京工业大学 Real-time measurement and control system for laser power
CN103399006A (en) * 2013-07-29 2013-11-20 重庆医科大学 Color RGB (red, green and blue)-component-based urine analysis device and processing method thereof
CN104266584A (en) * 2014-10-16 2015-01-07 北京理工大学 Automatic feedback light intensity adjusting device for laser self-mixing interference system
CN104792705A (en) * 2015-04-16 2015-07-22 西安交通大学 Laser power fluctuation monitoring and compensating device and method for photoacoustic spectrum measurement
CN105136431A (en) * 2015-08-24 2015-12-09 西安电子科技大学 Measurement system for optical element transmittance and reflectance based on acousto-optic modulation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
An Optical Technique for Concentration Measurement by Color Analysis;Tae-Hee Lee et al.;《The Transactions of the Korean Institute of Electrical Engineers》;20141231;第63卷(第8期);第1121-1127页 *
基于半反半透镜的新型尿液分析核心模块的研究;陈龙聪 等;《生物医学工程杂志》;20141231;第31卷(第6期);第1288页第1段-第1292页倒数第1段,图1-图3,表1 *
基于颜色传感器的尿液分析仪的研究与设计;王方;《中国优秀硕士学位论文全文数据库 工程科技II辑》;20141015(第10期);正文第1-27页 *

Also Published As

Publication number Publication date
CN105352891A (en) 2016-02-24

Similar Documents

Publication Publication Date Title
CN101620179A (en) Scanning type glass color difference measuring device and measuring method thereof
CN104568781A (en) Method for automatically detecting and evaluating color of laser beam emitting paper and quality of laser beams
CN202522512U (en) Device for automatically detecting color and luster as well as transparency of grease
CN115718101A (en) Solution color change detection method based on CIEL color space
CN103293152A (en) A method and an apparatus for end point detection in titration analysis
CN205192953U (en) Urine mummification analytical equipment based on optic fibre
CN107655626A (en) A kind of automation demarcation of pressure sensor and test equipment and its method of testing
CN105352891B (en) Urine desiccation analysis method and device based on beam splitter
CN108917594A (en) A kind of machine vision device measuring household board size
CN109000797A (en) A kind of radium-shine cigarette-brand chromatism measurement method
CN205229055U (en) Urine mummification analytical equipment based on many monochromatic light and optic fibre
CN105424692A (en) Urine dry-chemistry analysis device and analysis method based on multiple monochromatic light rays and optical fibers
US2356238A (en) Photoelectric apparatus for measuring color and turbidity
CN108801463A (en) A kind of radium-shine cigarette-brand color difference measuring device
CN205861532U (en) Full-automatic formaldehyde tester
CN204373781U (en) A kind of light beam laser paper color and light beam quality automatic checkout system
CN207318002U (en) A kind of automation calibration of pressure sensor and test equipment
CN105372239B (en) Urine desiccation analytical equipment and analysis method based on optical fiber
CN205808983U (en) Kiln on-line checking moisture content analyser
CN206740243U (en) A kind of multispectral Online color-difference measurement instrument
CN205333493U (en) Urine mummification analytical equipment based on beam splitter
CN208238727U (en) A kind of machine vision device measuring household board size
CN204758467U (en) High accuracy gold mark test paper reads appearance
CN209820655U (en) Dynamic temperature calibration device
CN208206304U (en) A kind of radium-shine cigarette-brand color difference measuring device

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20180216

Termination date: 20191215

CF01 Termination of patent right due to non-payment of annual fee