CN105343607A - Traditional Chinese medicine preparation for treating fallopian tube obstructive infertility caused by accumulation and stasis of damp-heat - Google Patents
Traditional Chinese medicine preparation for treating fallopian tube obstructive infertility caused by accumulation and stasis of damp-heat Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating fallopian tube obstructive infertility caused by accumulation and stasis of damp-heat and belongs to the technical field of traditional Chinese medicine. Aiming at the pathogenesis of fallopian tube obstructive infertility caused by accumulation and stasis of damp-heat, the traditional Chinese medicine preparation is prepared by decocting traditional Chinese medicines including flabelate maiden-hair herb, Chinese osbeckia herb, tuberous sword fern rhizome, oroxylum indicum bark, root of pilular adina, lindernia angustifolia (Benth.), lamium amplexicaule L., leaf and twig of sargent viburnum, agrimonia pilosa Ldb., herba sidae rhombifoliae, multiflora rose root, banyan leaf and adiantum capillus-veneris L. with water according to the theory of traditional Chinese medicine, wherein the traditional Chinese medicines are capable of clearing heat, promoting diuresis, promoting blood circulation to remove blood stasis and dredging the channels and collaterals. Through clinical experiments, the total effective rate is up to 90%.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, particularly relate to a kind of Chinese medicine preparation for the treatment of Accumulation of Dampness Heat and Blood Stasis type Infertility caused by fallopian tube obstruction.
Background technology
Modern medicine study proves, oviduct obstructive sterility pathogenesis is stagnant relevant with the stasis of blood, to be that the stasis of blood is stagnant do the key link of at least falling ill, no matter onset factor is nature and nurture, its result is all stagnant relevant with the vessels of the uterus stasis of blood, and principle for the treatment of should take blood stasis dispelling as elder generation, and salpingemphraxis is obstructed to be mostly caused by inflammation, all there is adhesion degeneration in various degree and function damage in tube chamber, meets the feature of TCM Blood Stasis & Blood pathology.Blood stasis is pathological product, is again paathogenic factor.Doctor trained in Western medicine applies anti-inflammatory treatment, hydrotubation, operation on fallopian tube redressment etc. usually, but curative effect owes satisfied, has that side effect is many, the problem such as have wound, expense higher.Higher for exploring a kind of recanalization rate, and the treatment oviduct obstructive sterility method that side effect obviously reduces, applicant is according to theory of Chinese medical science, and be developed into a kind of Chinese medicine with blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, through clinical verification, it is evident in efficacy.This Chinese medicine to blood vessel, blood flow pathologic changes and the fibrosis of tissue can play multiple action, stagnant, the loosen adhesion of the dredging stasis of blood, improves the fibrosis of fallopian tube lumen, promotes that the regeneration of damage inner membrance is its unique distinction.Also can reduce capillary permeability, reduce and ooze out edema, microcirculation and the histotrophic nutrition of pelvic cavity local can be improved, suppress monoamine oxidase, MAO vigor in tissue, suppress collagen fiber synthesis, improve immunity, regulate anabolism, absorb inflammatory lesions, be conducive to loosening of fallopian tube adhesion, promote reparation and the regeneration of tube chamber mucous epithelium, improve the function that fallopian tube transports ovum and sperm, and fertilization environment can be improved, increase uterus to the endometrial receptivity of cytula, thus improve pregnancy rate.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of Accumulation of Dampness Heat and Blood Stasis type Infertility caused by fallopian tube obstruction.The pathogenesis of Infertility caused by fallopian tube obstruction is summarized as in all evil stasis blocking born of the same parents by the traditional Chinese medical science, venation is obstructed, thus cause obstruction of fallopian tube and cause infertile, invading in evil poison fights mutually with blood stasis causes stagnation of blood stasis to be the basic of primary disease, and the generation of evil poison causes with heat primarily of wet, uterus is invaded on damp and hot, fight to tie with the turbid liquid of blood stasis and form blood stasis, stasis blocking collaterals of the uterus, cause punching and appoint obstructed, vessels of the uterus collaterals of the uterus is inaccessible and fall ill, and with the passing of time becomes disease.Therefore this disease should be controlled from wet, heat, the stasis of blood three aspect opinion, with clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling, meridians dredging is primary treatment principle.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment Accumulation of Dampness Heat and Blood Stasis type Infertility caused by fallopian tube obstruction is made up of the Chinese medicine of following weight portion: Herba Adianti Flabellulati 20-30 part, Herba Osbeckiae 15-25 part, Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 10-16 part, Cortex Oroxyli 12-18 part, Radix Adinae Piluliferae 25-35 part, Lindernia angustifolia (Benth.) Wettst. 25-35 part, Herba Lamii Amplexicaulis 12-18 part, Folium et Cacumen Viburni Sargentii 12-18 part, Herba silenes fortunei 50-60 part, Herba Sidae Rhombifoliae 20-30 part, Radix rosae multiflorae 6-12 part, Folium fici microcarpae 15-21 part, Herba cynodontis 25-35 part.
Preferred: Herba Adianti Flabellulati 25 parts, Herba Osbeckiae 20 parts, Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 13 parts, Cortex Oroxyli 15 parts, the Radix Adinae Piluliferae 30 parts, Lindernia angustifolia (Benth.) Wettst. 30 parts, Herba Lamii Amplexicaulis 15 parts, Folium et Cacumen Viburni Sargentii 15 parts, Herba silenes fortunei 55 parts, Herba Sidae Rhombifoliae 25 parts, Radix rosae multiflorae 9 parts, Folium fici microcarpae 18 parts, Herba cynodontis 30 parts.
Preparation method: traditionally make decoction.
Fang Zhong: Herba Adianti Flabellulati clearing away heat-damp and promoting diuresis, blood stasis slaking and dissipating edema; Herba Osbeckiae dispel the wind removing dampness, hemostasis repercussive; Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) clearing away heat-damp and promoting diuresis, subduing swelling and detoxicating.Cortex Oroxyli clearing away heat-damp and promoting diuresis, subduing swelling and detoxicating; Radix Adinae Piluliferae clearing away heat-damp and promoting diuresis, clots absorbing are subsided a swelling; Lindernia angustifolia (Benth.) Wettst. clearing away heat-damp and promoting diuresis, stomach function regulating blood stasis removing; Herba Lamii Amplexicaulis dispelling wind and removing obstruction in the collateral, reducing swelling and alleviating pain; Folium et Cacumen Viburni Sargentii dispelling wind and removing obstruction in the collateral, promoting blood circulation and detumescence; Herba silenes fortunei clearing away heat-damp and promoting diuresis, tonify deficiency are invigorated blood circulation; Herba Sidae Rhombifoliae clearing away heat-damp and promoting diuresis, evacuation of pus of invigorating blood circulation; Radix rosae multiflorae clearing away heat-damp and promoting diuresis, expelling wind and activating blood circulation, removing toxic substances; Folium fici microcarpae promoting blood circulation to remove blood stasis, antipyretic reason are wet; Herba cynodontis dispelling, collateral-activating, solution thermal hemostasis, granulation promoting.
Clinical data
1, physical data: all cases is all routine from I Out-patient Department patient 100 in April ,-2013 in March, 2010, be divided into treatment group and matched group at random, treatment group 50 example, 23 ~ 42 years old age, primary infertility 28 example, secondary infertility 22 example, one-sided salpingemphraxis 21 example, bilateral salpingo blocks 29 examples.Matched group 50 example, 22 ~ 42 years old age, primary infertility 25 example, secondary infertility 25 example, one-sided salpingemphraxis 24 example, bilateral salpingo blocks 26 examples, two groups of patient's physical data there was no significant differences (P > 0.05), have comparability.
2, Western medicine diagnose standard is with reference to " infertility therapy of combining Chinese and Western medicine " and the 7th edition " obstetrics and gynecology " teaching material of People's Health Publisher's publication; Tcm diagnosis standard drafts salpingitic infecundity Accumulation of Dampness Heat and Blood Stasis type standard with reference to " new Chinese medicine guideline of clinical investigations " and " clinical disease diagnosis is according to curing improvement standard (the 2nd edition) ".
3, inclusive criteria meets Western medicine diagnose standard and tcm syndrome syndrome differential diagnosis standard person; 22 ~ 36 years old age; Menstrual cycle is 28 ~ 30d person; Signature Informed Consent Form person.
3 exclusion standard interstitial tubal, isthmus, ampulla obstructor; Other reasons such as congenital physiological defect or deformity, immunity, heredity, endocrine cause infertile person; Be associated with on inspection and confirm endometriosis, adenomyosis, hysteromyoma person; Turn out to be cervical lesions on inspection or have genital tuberculosis person; Bridegroom's or husband's side reproductive function exception person; Be associated with severe primary disease and the psychiatric patients such as cardiovascular, liver, kidney and hemopoietic system.
5, Therapeutic Method treatment group takes Chinese medicine preparation of the present invention, takes Herba Adianti Flabellulati 25g, Herba Osbeckiae 20g, Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 13g, Cortex Oroxyli 15g, Radix Adinae Piluliferae 30g, Lindernia angustifolia (Benth.) Wettst. 30g, Herba Lamii Amplexicaulis 15g, Folium et Cacumen Viburni Sargentii 15g, Herba silenes fortunei 55g, Herba Sidae Rhombifoliae 25g, Radix rosae multiflorae 9g, Folium fici microcarpae 18g, Herba cynodontis 30g.Take medicine after clean period, traditionally make decoction, every day 1 dose, menstrual period stop using, and within 1 month, are 1 course for the treatment of, totally 3 courses for the treatment of; Matched group: western medical treatment routinely.
6, criterion of therapeutical effect combines originally study and define with reference to " new Chinese medicine guideline of clinical investigations ": 1. cure: treat the person of becoming pregnant after 3 courses for the treatment of; 2. effective: after treating 3 courses for the treatment of, though the one-sided unobstructed person of fallopian tube of not becoming pregnant; 3. invalid: through treating continuously, do not become pregnant and all obstructed person of bilateral.
7, therapeutic outcome two groups treats comparative result after 3 courses for the treatment of
| Group | n | Cure | Effectively | Invalid | Total effective rate |
| Treatment group | 50 | 30 | 15 | 5 | 90％ |
| Matched group | 50 | 22 | 12 | 16 | 68％ |
Detailed description of the invention
Embodiment one: take Herba Adianti Flabellulati 20g, Herba Osbeckiae 15g, Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 10g, Cortex Oroxyli 12g, Radix Adinae Piluliferae 25g, Lindernia angustifolia (Benth.) Wettst. 25g, Herba Lamii Amplexicaulis 12g, Folium et Cacumen Viburni Sargentii 12g, Herba silenes fortunei 50g, Herba Sidae Rhombifoliae 20g, Radix rosae multiflorae 6g, Folium fici microcarpae 15g, Herba cynodontis 25g, traditionally make decoction.
Embodiment two: take Herba Adianti Flabellulati 25g, Herba Osbeckiae 20g, Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 13g, Cortex Oroxyli 15g, Radix Adinae Piluliferae 30g, Lindernia angustifolia (Benth.) Wettst. 30g, Herba Lamii Amplexicaulis 15g, Folium et Cacumen Viburni Sargentii 15g, Herba silenes fortunei 55g, Herba Sidae Rhombifoliae 25g, Radix rosae multiflorae 9g, Folium fici microcarpae 18g, Herba cynodontis 30g, traditionally make decoction.
Embodiment three: take Herba Adianti Flabellulati 30g, Herba Osbeckiae 25g, Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 16g, Cortex Oroxyli 18g, Radix Adinae Piluliferae 35g, Lindernia angustifolia (Benth.) Wettst. 35g, Herba Lamii Amplexicaulis 18g, Folium et Cacumen Viburni Sargentii 18g, Herba silenes fortunei 60g, Herba Sidae Rhombifoliae 30g, Radix rosae multiflorae 12g, Folium fici microcarpae 21g, Herba cynodontis 35g, traditionally make decoction.
Claims (2)
1. treat a Chinese medicine preparation for Accumulation of Dampness Heat and Blood Stasis type Infertility caused by fallopian tube obstruction, it is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Herba Adianti Flabellulati 20-30 part, Herba Osbeckiae 15-25 part, Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 10-16 part, Cortex Oroxyli 12-18 part, Radix Adinae Piluliferae 25-35 part, Lindernia angustifolia (Benth.) Wettst. 25-35 part, Herba Lamii Amplexicaulis 12-18 part, Folium et Cacumen Viburni Sargentii 12-18 part, Herba silenes fortunei 50-60 part, Herba Sidae Rhombifoliae 20-30 part, Radix rosae multiflorae 6-12 part, Folium fici microcarpae 15-21 part, Herba cynodontis 25-35 part.
2. a kind of Chinese medicine preparation for the treatment of Accumulation of Dampness Heat and Blood Stasis type Infertility caused by fallopian tube obstruction as claimed in claim 1, is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: preferred: Herba Adianti Flabellulati 25 parts, Herba Osbeckiae 20 parts, Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 13 parts, Cortex Oroxyli 15 parts, the Radix Adinae Piluliferae 30 parts, Lindernia angustifolia (Benth.) Wettst. 30 parts, Herba Lamii Amplexicaulis 15 parts, Folium et Cacumen Viburni Sargentii 15 parts, Herba silenes fortunei 55 parts, Herba Sidae Rhombifoliae 25 parts, Radix rosae multiflorae 9 parts, Folium fici microcarpae 18 parts, Herba cynodontis 30 parts.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105726976A (en) * | 2016-04-11 | 2016-07-06 | 吴刚 | Traditional Chinese medicine for treating unruptured tubal pregnancy and preparation method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102366508A (en) * | 2011-09-30 | 2012-03-07 | 张丙焕 | Traditional Chinese medicine preparation for treating obstructive infertility of fallopian tube |
| CN103877282A (en) * | 2014-03-26 | 2014-06-25 | 朱凤彩 | Traditional Chinese medicine preparation for treating salpinx obstructive infertility caused by accumulation and stasis of damp-heat |
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- 2015-11-19 CN CN201510835408.5A patent/CN105343607A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102366508A (en) * | 2011-09-30 | 2012-03-07 | 张丙焕 | Traditional Chinese medicine preparation for treating obstructive infertility of fallopian tube |
| CN103877282A (en) * | 2014-03-26 | 2014-06-25 | 朱凤彩 | Traditional Chinese medicine preparation for treating salpinx obstructive infertility caused by accumulation and stasis of damp-heat |
Non-Patent Citations (2)
| Title |
|---|
| 冯英培: "中药口服加灌肠治疗输卵管阻塞性不孕症湿热瘀结证临床观察", 《中医药临床杂志》 * |
| 南京中医药大学编: "《中药大辞典》", 31 March 2006, 上海科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105726976A (en) * | 2016-04-11 | 2016-07-06 | 吴刚 | Traditional Chinese medicine for treating unruptured tubal pregnancy and preparation method |
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