CN105343463A - Traditional Chinese medicinal preparation for treating hyperostosis and preparation method of traditional Chinese medicinal preparation - Google Patents
Traditional Chinese medicinal preparation for treating hyperostosis and preparation method of traditional Chinese medicinal preparation Download PDFInfo
- Publication number
- CN105343463A CN105343463A CN201510723514.4A CN201510723514A CN105343463A CN 105343463 A CN105343463 A CN 105343463A CN 201510723514 A CN201510723514 A CN 201510723514A CN 105343463 A CN105343463 A CN 105343463A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- medicine preparation
- herba
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the field of a traditional Chinese medicine, and relates to a traditional Chinese medicinal preparation for treating hyperostosis and a preparation method of the traditional Chinese medicinal preparation. The traditional Chinese medicinal preparation is mainly prepared from the following raw materials in parts by weight: 16-26 parts of folium mori, 18-26 parts of ligusticum wallichii, 15-20 parts of sabia japonica, 12-18 parts of verbena officinalis, 14-20 parts of nutgrass flatsedge, 14-22 parts of schisandra propinqua baill., 8-18 parts of cicer arietinum, 10-16 parts of radix puerariae, 4-12 parts of Chinese yam, 6-12 parts of herba epimedii, 5-15 parts of allium macrostemon and 6-16 parts of liquorice root. The traditional Chinese medicinal preparation disclosed by the invention has functions of promoting circulation of blood and removing stasis, dredging channels and activating collaterals, expelling wind and eliminating cold and dampness, tonifying kidney and strengthening tendons and bones; and the traditional Chinese medicinal preparation disclosed by the invention is strong in penetration, rapid to take effect, strongly targeted, free from reoccurrence, simple and convenient in medication and free from toxic and side effects.
Description
Technical field
The invention belongs to tcm field, be specifically related to a kind of Chinese medicine preparation for the treatment of hyperosteogeny and preparation method thereof.
Background technology
Hyperosteogeny be also called hyperplastic osteoarthritis, osteoarthritis, degenerative joint disease, senile arthritis,
Hypertrophiarthritis.Usually occur in the positions such as cervical vertebra, lumbar vertebra, knee, heel, cardinal symptom is arthralgia, often betides daystart, and after movable, pain alleviates on the contrary, but as hyperactivity, pain can increase the weight of again.Check the swelling of affected joints visible joint, tenderness, have friction sense or " click clatter " sound time movable, the person of being in a bad way can have the symptom of amyotrophy and joint deformity.The traditional Chinese medical science thinks that primary disease is relevant with wound, strain, obstruction of collaterals by blood stasis, the damp that is affected by the cold, phlegm resistance, caused by liver and kidney deficiency etc.Motherland's medical science think hyperosteogeny often because experiencing wind, cold, wet, hot wound, strain cause neck, lumbar vertebra, knee hyperplasia change and occur, and then pressuring neural root, impatency meridians, cause that QI-blood circulation is smooth, qi depression to blood stasis.Doctor trained in Western medicine then thinks that the cause of disease mainly causes bone network Leukopenia to cause because the calcareous forfeiture of bone and calcium ion metabolic function go down.
The reason affecting hyperosteogeny generation has a lot, mainly contains the congenital malformation, metabolic factor, Nervous and Mental Factors etc. of age factor, chronic strain, wound, bottleneck throat inflammation, developmental spinal stenosis, cervical vertebra.Treatment bone matrix hyperplasia there is no effective medicine both at home and abroad at present, and the traditional Chinese medical science is mainly with invigorating the liver and kidney, and wind-damp dispelling, reducing swelling and alleviating pain, relaxing muscles and tendons to promote blood circulation is main, is aided with existing Chinese herbal medicine and treats, and the Therapeutic Principle of doctor trained in Western medicine is antiinflammatory, analgesia.Conventional method has galvanoiontophoresis method, ultraviolet therapy, massage and traction, acupuncture, forces on, operative treatment etc.Galvanoiontophoresis method has given full play to the effect of medicine, but is liquid because importing medicine, volatile, and drug effect is not lasting, limits the therapeutic effect of the method.Massage and the effect of the complete outer power of drawing method, only integrally regulating in human body locally treating but to ignore, therefore, can only play temporary transient analgesic effect, and can not reach the object for the treatment of.Acupuncture method can restore menstrual flow and invigorate blood circulation and have analgesic effect, can eliminate edema and the inflammation of local, but can only help out concerning acupuncture hyperosteogeny.Western medical treatment commonly uses the antibiotic medicine such as dexamethasone, ibuprofen or analgesic treatment hyperosteogeny, also the employing androgen had, vitamin, sour calcium, long-acting calcitonin are treated, arthroncus has hydrops, and person takes local to extract hydrops or partial closure etc., curative effect is relief of symptoms, therapeutic process has certain damage to liver, kidney, gastrointestinal, just take stopgap measures and do not effect a permanent cure, the state of an illness easily recurs.Therefore select Therapeutic Method that is timely, regular, effective, that do not have side effect to be crucial, the advantage that external traditional Chinese medicinal application treats hyperosteogeny maximum is to effect a radical cure from pathology.
Nowadays in treatment hyperosteogeny, be difficult to control by the dose of internal organs decomposition arrival disease sites because oral medicine also exists medicine, the property of medicine is strong injures internal organs, the property of medicine is low does not reach the drawback of therapeutic effect, and sight has turned to by people to be needed on the liniment of scalable property of medicine intensity according to the individual variation of people.Record according to traditional Chinese medical science canon Huangdi's Internal Classics, in tradition doctor bone strange method, the most effective means are that room temperature in water-soluble transdermal art dresses therapy, be commonly called as " poultice ", refer to and reconcile into pasty state with watery wine etc. after being pulverized by high-quality Chinese medicine formula, apply a kind of transdermal methods carrying out in local treating.Feature does not heat, and dose is large, dissociates.What Gu had " one sticks with paste gas hundred cream " says, act on affected site, its usefulness surmounts common unguentum tens, and even hundreds of times, has penetration strong, absorbs the features such as fast.
Chinese patent application CN201210366681 discloses a kind of Chinese pill for curing hyperosteogeny, certain weight ratio is pressed formulated by Radix Rehmanniae Preparata, Herba Cistanches, Radix Puerariae, Rhizoma Drynariae, Herba Epimedii, Herba Pyrolae, Caulis Spatholobi and Semen Raphani, this Drug therapy hyperosteogeny instant effect, effective percentage is high, but cure the symptoms, not the disease, there is the deficiency of easily recurrence.
Summary of the invention
For solving the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine preparation for the treatment of hyperosteogeny and preparation method thereof.
For realizing object of the present invention, the present inventor is according to the research of theory of Chinese medical science and clinical test repeatedly and checking, provide a kind of Chinese medicine preparation for the treatment of hyperosteogeny, it is characterized in that, described Chinese medicine preparation is mainly prepared from by the raw material of following parts by weight:
Folium Mori 16-26 part, Rhizoma Chuanxiong 18-26 part, Caulis Sinomenii 15-20 part, Herba Verbenae 12-18 part, umbrella plant 14-20 part, Herba Schisandrae intermediae 14-22 part, chickpea 8-18 part, Radix Puerariae 10-16 part, Rhizoma Dioscoreae 4-12 part, Herba Epimedii 6-12 part, Bulbus Allii Macrostemonis 5-15 part and Radix Glycyrrhizae 6-16 part.
Further, described Chinese medicine preparation forms primarily of the raw material of following parts by weight:
16 parts, Folium Mori, Rhizoma Chuanxiong 18 parts, Caulis Sinomenii 15 parts, Herba Verbenae 12 parts, umbrella plant 14 parts, Herba Schisandrae intermediae 14 parts, chickpea 8 parts, Radix Puerariae 10 parts, Rhizoma Dioscoreae 4 parts, Herba Epimedii 6 parts, Bulbus Allii Macrostemonis 5 parts and 6 parts, Radix Glycyrrhizae.
Further, described Chinese medicine preparation forms primarily of the raw material of following parts by weight:
26 parts, Folium Mori, Rhizoma Chuanxiong 26 parts, Caulis Sinomenii 20 parts, Herba Verbenae 18 parts, umbrella plant 20 parts, Herba Schisandrae intermediae 22 parts, chickpea 18 parts, Radix Puerariae 16 parts, Rhizoma Dioscoreae 12 parts, Herba Epimedii 12 parts, Bulbus Allii Macrostemonis 15 parts and 16 parts, Radix Glycyrrhizae.
Further, described Chinese medicine preparation forms primarily of the raw material of following parts by weight:
20 parts, Folium Mori, Rhizoma Chuanxiong 22 parts, Caulis Sinomenii 17 parts, Herba Verbenae 16 parts, umbrella plant 18 parts, Herba Schisandrae intermediae 20 parts, chickpea 14 parts, Radix Puerariae 14 parts, Rhizoma Dioscoreae 8 parts, Herba Epimedii 8 parts, Bulbus Allii Macrostemonis 10 parts and 12 parts, Radix Glycyrrhizae.
Further, described Chinese medicine preparation is made into ointment or emplastrum.
Source, the nature and flavor of Chinese medicine preparation of the present invention Chinese crude drug used, return through and effect:
Folium Mori: this product is the dried leaves of moraceae plants Mulberry.Bitter in the mouth, sweet, cold nature; Return lung, Liver Channel; Wind and heat dispersing, liver heat removing and eyesight improving, cooling blood for hemostasis.
Rhizoma Chuanxiong: this product is the dry rhizome of samphire Rhizoma Chuanxiong.Acrid in the mouth, warm in nature; Return liver, gallbladder, pericardium channel; Blood-activating and qi-promoting, wind-expelling pain-stopping.
Caulis Sinomenii: this product is stem and leaf or the root of Sabiaceae plant Caulis Sinomenii.Bitter in the mouth, pungent; Warm in nature.Return Liver Channel.Expelling wind and removing dampness; Promoting blood circulation and detoxication.Main air pain of dampness syndrome; The arthroncus of knee; Edema; Foot gas; Treating swelling and pain by traumatic injury; Fracture; Deep abscess; Osteomyelitis; Suppurative arthritis; Spondylitis; Sore swollen toxin; Skin pruritus.
Herba Verbenae: this product is the dry aerial parts of Verbenaceae Herba Verbenae.Bitter in the mouth; Cool in nature.Return liver, spleen channel.Promoting blood circulation to remove blood stasis, preventing the attack (or recurrence) of malaria, removing toxic substances, inducing diuresis to remove edema, for lump in the abdomen, amenorrhea dysmenorrhea, malaria, sore throat, carbuncle, edema, pyretic stranguria.
Umbrella plant: this product is the stem and leaf of sedge cyperus alternifolius.Sweet in the mouth, micro-hardship; Cool in nature.Return Liver Channel.Promoting flow of QI and blood; Removing toxic substances.Main blood stasis is had a pain; Snake bite and insect sting.
Herba Schisandrae intermediae: this product is rattan and the root that Schisandraceae Plant closes stamen Fructus Schisandrae Chinensis.Bitter in the mouth, pungent; Property is put down.Return Liver Channel.Heat-clearing and toxic substances removing; Promoting blood circulation and detumescence.Main flow sense; Carbuncle sore tumefacting virus; Venom; Rheumatic numbness; Traumatic injury.
Chickpea: this product is the seed of leguminous plant chickpea.Sweet in the mouth; Property is put down.Attach to the lung and stomach meridians.Heat-clearing and toxic substances removing.Master quenches one's thirst, hepatitis, beriberi.
Radix Puerariae: this product is the dry root of legume pueraria lobata or Radix Puerariae rattan.Sweet in the mouth, pungent; Cool in nature.Return spleen, stomach warp.Expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal, for fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quenches one's thirst, measles without adequate eruption, and hematodiarrhoea, has loose bowels; Hypertension neck pain.
Rhizoma Dioscoreae: this product is the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae.Sweet in the mouth; Property is put down.Return spleen, lung, kidney channel.Spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.
Herba Epimedii: this product is the dry aerial parts of Berberidaceae plant Herba Epimedii, Epimedium sagittatum, E. Pubescens, Epimedium wushanense or Herba Epimedii.Acrid in the mouth, sweet; Warm in nature.Return liver, kidney channel.Kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
Bulbus Allii Macrostemonis: this product is the dry bulb of liliaceous plant Allium macrostemon or Chinese onion.Acrid in the mouth, hardship; Warm in nature.Return lung, stomach, large intestine channel.Activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving, for thoracic obstruction pain, phlegm retention cough with asthma is heavy after letting out dysentery.
Radix Glycyrrhizae: this product is the dry root of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..Sweet in the mouth; Property is put down.Gui Jing, GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The prescription analysis of Chinese medicine of the present invention:
According to the compatibility theory of the traditional Chinese medical science to the dialectical and Chinese crude drug for the treatment of hyperosteogeny, in conjunction with the body constitution of modern and the feature of modern pharmaceutical technology, the collocation ingredients of reasonable science, forms Chinese prescription of the present invention.Prescription of the present invention is with Folium Mori, Rhizoma Chuanxiong, Caulis Sinomenii for monarch drug, promoting blood circulation and stopping pain, expelling wind and removing dampness, dispersing cold for relieving pain; With Herba Verbenae, umbrella plant, Herba Schisandrae intermediae for ministerial drug, promoting blood circulation and detumescence, promoting flow of QI and blood; With chickpea, Radix Puerariae, Rhizoma Dioscoreae for adjuvant drug, activating YANG and eliminating stagnation, heat-clearing and toxic substances removing; With Herba Epimedii, Bulbus Allii Macrostemonis and Radix Glycyrrhizae for making medicine, promoting blood circulation to restore menstrual flow, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription; The all medicines of monarch coordinate, and collaborative promotion, complements each other, finally reach blood circulation promoting and blood stasis dispelling, soothing the channels and quicking the network vessels, functions dispelling wind and clearing away cold, removing dampness, effect of the kidney invigorating bone and muscle strengthening, be applicable to hyperosteogeny patient.
The preparation method of Chinese medicine preparation of the present invention is as follows:
S1 gets Folium Mori, washes away impurity, 50 DEG C of hot air dryings 5 hours, and control moisture is 3-8%, pulverizes, and crosses 40-60 mesh sieve, obtains coarse powder; Coarse powder is sucked air-stream type ultrafine pulverizer and carry out micronizing, pulverize pressure 0.5MPa, charging rate is 30mg/s, carries out micronizing respectively after drying, crosses 800 mesh sieves, obtains Ultra-fine Powder of Mulberry Leaves;
S2 gets Rhizoma Chuanxiong, Caulis Sinomenii, Herba Verbenae, umbrella plant, Herba Schisandrae intermediae, chickpea, Radix Puerariae, Rhizoma Dioscoreae, Herba Epimedii, Bulbus Allii Macrostemonis and Radix Glycyrrhizae, add the distilled water of above-mentioned medical material 3-6 times weight, soak 12-24 hour, decoct 3-5 hour, filter, it is the concentrated solution of 1.20-1.25 that filtrate is concentrated into 60-70 DEG C of relative density;
The concentrated solution that the Ultra-fine Powder of Mulberry Leaves that step S1 obtains by S3 and step S2 obtain mixes, and dry, pulverize, and to obtain final product.
Chinese medicine preparation of the present invention, come from the achievement in research of China's Chinese medical theory and modern pharmacology, through pharmacodynamic experiment research, clinical practice treatment use, prove its determined curative effect in treatment hyperosteogeny, have no adverse reaction, there are blood circulation promoting and blood stasis dispelling, soothing the channels and quicking the network vessels, functions dispelling wind and clearing away cold, removing dampness, effect of the kidney invigorating bone and muscle strengthening.Chinese medicine preparation instant effect of the present invention, with strong points, skin absorbs fast, and bioavailability is high, and it is convenient to be suitable for, and has no side effect.
Detailed description of the invention
Further describe the present invention below by way of specific embodiment, the present invention is not limited only to following examples.Within the scope of the invention or not departing from content of the present invention, spirit and scope, the change carried out the present invention, combination or replacement, be apparent for a person skilled in the art, be all included within the scope of the present invention.
eXAMPLE l
The embodiment of the present invention 1 Chinese medicine preparation is prepared from by the raw material of following parts by weight:
16 parts, Folium Mori, Rhizoma Chuanxiong 18 parts, Caulis Sinomenii 15 parts, Herba Verbenae 12 parts, umbrella plant 14 parts, Herba Schisandrae intermediae 14 parts, chickpea 8 parts, Radix Puerariae 10 parts, Rhizoma Dioscoreae 4 parts, Herba Epimedii 6 parts, Bulbus Allii Macrostemonis 5 parts and 6 parts, Radix Glycyrrhizae.
Preparation method:
S1 gets Folium Mori, washes away impurity, 50 DEG C of hot air dryings 5 hours, and controlling moisture is 3%, pulverizes, and crosses 40 mesh sieves, obtains coarse powder; Coarse powder is sucked air-stream type ultrafine pulverizer and carry out micronizing, pulverize pressure 0.5MPa, charging rate is 30mg/s, carries out micronizing respectively after drying, crosses 800 mesh sieves, obtains Ultra-fine Powder of Mulberry Leaves;
S2 gets Rhizoma Chuanxiong, Caulis Sinomenii, Herba Verbenae, umbrella plant, Herba Schisandrae intermediae, chickpea, Radix Puerariae, Rhizoma Dioscoreae, Herba Epimedii, Bulbus Allii Macrostemonis and Radix Glycyrrhizae, add the distilled water of above-mentioned medical material 3 times of weight, soak 12 hours, decoct 3 hours, filter, it is the concentrated solution of 1.20 that filtrate is concentrated into 60 DEG C of relative densities;
The concentrated solution that the Ultra-fine Powder of Mulberry Leaves that step S1 obtains by S3 and step S2 obtain mixes, and dry, pulverize, and adds corresponding adjuvant, makes ointment.
embodiment 2
The embodiment of the present invention 2 Chinese medicine preparation is prepared from by the raw material of following parts by weight:
26 parts, Folium Mori, Rhizoma Chuanxiong 26 parts, Caulis Sinomenii 20 parts, Herba Verbenae 18 parts, umbrella plant 20 parts, Herba Schisandrae intermediae 22 parts, chickpea 18 parts, Radix Puerariae 16 parts, Rhizoma Dioscoreae 12 parts, Herba Epimedii 12 parts, Bulbus Allii Macrostemonis 15 parts and 16 parts, Radix Glycyrrhizae.
Preparation method is similar to Example 1, adds corresponding adjuvant, makes emplastrum.
embodiment 3
The embodiment of the present invention 3 Chinese medicine preparation is prepared from by the raw material of following parts by weight:
20 parts, Folium Mori, Rhizoma Chuanxiong 22 parts, Caulis Sinomenii 17 parts, Herba Verbenae 16 parts, umbrella plant 18 parts, Herba Schisandrae intermediae 20 parts, chickpea 14 parts, Radix Puerariae 14 parts, Rhizoma Dioscoreae 8 parts, Herba Epimedii 8 parts, Bulbus Allii Macrostemonis 10 parts and 12 parts, Radix Glycyrrhizae.
Preparation method is similar to Example 1, adds corresponding adjuvant, makes ointment.
experimental example 1, Chinese medicine preparation of the present invention are to the experimental study of the rat pain lured caused by pain agent acetic acid
1, experimental animal: get regular grade SD rat 60, body weight (180 ± 12g), male and female half and half, are divided into 6 groups at random, often organize 10.
2, trial drug and dosage regimen:
Trial drug is the Chinese medicine preparation ointment medicine of the present invention that the embodiment of the present invention 1 obtains.Get 3 groups of rats, be labeled as high dose group (1000mg/kg), middle dosage group (800mg/kg) and low dose group (600mg/kg), modeling according to dosage smears 3 times in Test sites in first 2 days every day, and modeling is implemented to smear for the last time for first 1 hour.
Model control group: get 1 group of rat, first 2 days of modeling, smears 3 times in Test sites by equal-volume normal saline every day, and modeling is implemented to smear for the last time for first 1 hour.
Positive controls: positive control drug is YUNNAN BAIYAO cream (the accurate word Z20073015 of traditional Chinese medicines, Yunnan Baiyao Group Wuxi Medicine Co., Ltd.), smears 3 times in Test sites by medicine by suggestion using dosage every day, and modeling is implemented to smear for the last time for first 1 hour.
3, experimentation: the cervical region of experimental rat, waist 8% sodium sulfide saturated solution are lost hair or feathers, depilation area cervical region is about 1.3cm × 1.1cm, and waist is about 2.2cm × 1.6cm.1h after last administration, every Mus lumbar injection 0.7% glacial acetic acid 0.1ml/10g, after observed and recorded injection glacial acetic acid, rat starts to occur incubation period and the writhing number of times of rat in 30min after there is pain reaction of pain reaction.
4, result of the test: as shown in table 1.
The impact of the rat pain caused by table 1 Chinese medicine preparation Dichlorodiphenyl Acetate of the present invention
Note: compare with model control group, positive controls △ △ P0.01; Compare with model control group, Chinese medicine preparation drug test group of the present invention
*p0.01; Compare with positive controls, Chinese medicine preparation drug test group of the present invention
##p0.01.
5, conclusion (of pressure testing): can be found out by the result of the test of table 1, compare with model control group, there were significant differences to the treatment of hyperosteogeny for the high and low dose of Chinese medicine preparation of the present invention, can significantly improve experimental rat incubation period and pain threshold.Therapeutic effect is better than positive control, difference have statistical significance (
p0.01).
the clinical trial of experimental example 2, Chinese medicine preparation of the present invention
(1) study subject is selected
Tcm diagnosis standard: the content of " hyperosteogeny " of reference " Chinese medical disease Standardization of diagnosis and curative effect " (2012 editions) and " new Chinese medicine guideline of clinical investigations " is drafted.Diagnostic criteria is:
1. suffering oppression and irritation appears in diseased region, and wherein cervical spondylosis patient has long-term neck shoulder and back ache, dizzy head
Bitterly, the numb or symptom such as unfavorable of changing one's position of both hands.
2. x-ray to take the photograph in sheet visible cervical vertebra just, lateral projection, left and right oblique film, cervical vertebrae physiological is bending to be straightened or instead to bend, prolapse of lumbar intervertebral disc, intervertebral foramina stenosis, vertebral body hyperosteogeny; The positive side of knee joint is visible: proximal ends of tibia, and the interior lateral condyle hyperosteogeny of distal part of femur is formed, lower edge, spinous process of tibia on patella, and calcaneal tuberosity bony spur is formed.
1, physical data
Choose in January, 2012 ~ 2014 year January the medical patient of Orthopaedics Clinic totally 200 routine hyperosteogeny patients be divided into two groups at random, often organize 100 examples, age 25-75 year, 45 years old mean age.Two groups of patients no difference of science of statistics (P > 0.05) in age, sex, disease time, previously health history, ordinary circumstance etc. has comparability.
2, test method
Treatment group: trial drug is Chinese medicine preparation ointment medicine of the present invention prepared by the embodiment of the present invention 3, every day three times, 7 days is a course for the treatment of, evaluates curative effect after 2 courses for the treatment of.
Matched group: matched group YUNNAN BAIYAO spray (the accurate word Z20025478 of traditional Chinese medicines), every day three times, 7 days is a course for the treatment of, evaluates curative effect after 2 courses for the treatment of.
3, curative effect determinate standard
Criterion of therapeutical effect: with reference to " practical combination of Chinese and Western medicine diagnoses and treatment " muscle tendon soft tissue injury criterion of therapeutical effect.
1. invalid: before and after treatment, sings and symptoms is not any change, or aggravation.
2. effective: the improvement of condition of illness and sign limited extent, the recovery of function limited extent.
3. remarkable: condition of illness and sign disappear substantially, functional rehabilitation is normal, but still can go out sense of discomfort because of Changes in weather or tired etc.
4. fully recover: condition of illness and sign disappear completely, and function recovers normal completely.
4, therapeutic outcome: as shown in table 2
Table 2 therapeutic effect
This clinical trial matched group is the medicine YUNNAN BAIYAO cream of conventional treatment muscle tendon soft tissue injury, and compared by the treatment clinical effectiveness of itself and Chinese medicine preparation of the present invention, result of the test illustrates that the evident in efficacy of Chinese medicine preparation of the present invention is better than matched group medicine.Clinical testing data shows, and the effect cure rate of matched group Drug therapy hyperosteogeny reaches 45.0%; And Chinese medicine preparation treatment hyperosteogeny effect recovery from illness efficiency of the present invention is up to 64.0%, total effective rate is 97.0%, apparently higher than the total effective rate of contrast medicine 72.0%.Clinical trial results proves Chinese medicine preparation of the present invention treatment hyperosteogeny Be very effective, and have reducing swelling and alleviating pain curative effect, can be used as clinical treatment hyperosteogeny medicine and use, clinical generalization value is high.
Claims (6)
1. treat a Chinese medicine preparation for hyperosteogeny, it is characterized in that, described Chinese medicine preparation forms primarily of the raw material of following parts by weight:
Folium Mori 16-26 part, Rhizoma Chuanxiong 18-26 part, Caulis Sinomenii 15-20 part, Herba Verbenae 12-18 part, umbrella plant 14-20 part, Herba Schisandrae intermediae 14-22 part, chickpea 8-18 part, Radix Puerariae 10-16 part, Rhizoma Dioscoreae 4-12 part, Herba Epimedii 6-12 part, Bulbus Allii Macrostemonis 5-15 part and Radix Glycyrrhizae 6-16 part.
2. the Chinese medicine preparation for the treatment of hyperosteogeny as claimed in claim 1, it is characterized in that, described Chinese medicine preparation forms primarily of the raw material of following parts by weight:
16 parts, Folium Mori, Rhizoma Chuanxiong 18 parts, Caulis Sinomenii 15 parts, Herba Verbenae 12 parts, umbrella plant 14 parts, Herba Schisandrae intermediae 14 parts, chickpea 8 parts, Radix Puerariae 10 parts, Rhizoma Dioscoreae 4 parts, Herba Epimedii 6 parts, Bulbus Allii Macrostemonis 5 parts and 6 parts, Radix Glycyrrhizae.
3. the Chinese medicine preparation for the treatment of hyperosteogeny as claimed in claim 1, it is characterized in that, described Chinese medicine preparation forms primarily of the raw material of following parts by weight:
26 parts, Folium Mori, Rhizoma Chuanxiong 26 parts, Caulis Sinomenii 20 parts, Herba Verbenae 18 parts, umbrella plant 20 parts, Herba Schisandrae intermediae 22 parts, chickpea 18 parts, Radix Puerariae 16 parts, Rhizoma Dioscoreae 12 parts, Herba Epimedii 12 parts, Bulbus Allii Macrostemonis 15 parts and 16 parts, Radix Glycyrrhizae.
4. the Chinese medicine preparation for the treatment of hyperosteogeny as claimed in claim 1, it is characterized in that, described Chinese medicine preparation forms primarily of the raw material of following parts by weight:
20 parts, Folium Mori, Rhizoma Chuanxiong 22 parts, Caulis Sinomenii 17 parts, Herba Verbenae 16 parts, umbrella plant 18 parts, Herba Schisandrae intermediae 20 parts, chickpea 14 parts, Radix Puerariae 14 parts, Rhizoma Dioscoreae 8 parts, Herba Epimedii 8 parts, Bulbus Allii Macrostemonis 10 parts and 12 parts, Radix Glycyrrhizae.
5. the Chinese medicine preparation of the treatment hyperosteogeny as described in as arbitrary in claim 1-4, it is characterized in that, described Chinese medicine preparation is made into ointment or emplastrum.
6. the preparation method of the Chinese medicine preparation of the treatment hyperosteogeny as described in as arbitrary in claim 1-4, it is characterized in that, the preparation method of described Chinese medicine preparation comprises following steps:
S1 gets Folium Mori, washes away impurity, 50 DEG C of hot air dryings 5 hours, and control moisture is 3-8%, pulverizes, and crosses 40-60 mesh sieve, obtains coarse powder; Coarse powder is sucked air-stream type ultrafine pulverizer and carry out micronizing, pulverize pressure 0.5MPa, charging rate is 30mg/s, carries out micronizing respectively after drying, crosses 800 mesh sieves, obtains Ultra-fine Powder of Mulberry Leaves;
S2 gets Rhizoma Chuanxiong, Caulis Sinomenii, Herba Verbenae, umbrella plant, Herba Schisandrae intermediae, chickpea, Radix Puerariae, Rhizoma Dioscoreae, Herba Epimedii, Bulbus Allii Macrostemonis and Radix Glycyrrhizae, add the distilled water of above-mentioned medical material 3-6 times weight, soak 12-24 hour, decoct 3-5 hour, filter, it is the concentrated solution of 1.20-1.25 that filtrate is concentrated into 60-70 DEG C of relative density;
The concentrated solution that the Ultra-fine Powder of Mulberry Leaves that step S1 obtains by S3 and step S2 obtain mixes, and dry, pulverize, and to obtain final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510723514.4A CN105343463A (en) | 2015-10-29 | 2015-10-29 | Traditional Chinese medicinal preparation for treating hyperostosis and preparation method of traditional Chinese medicinal preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510723514.4A CN105343463A (en) | 2015-10-29 | 2015-10-29 | Traditional Chinese medicinal preparation for treating hyperostosis and preparation method of traditional Chinese medicinal preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105343463A true CN105343463A (en) | 2016-02-24 |
Family
ID=55319621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510723514.4A Withdrawn CN105343463A (en) | 2015-10-29 | 2015-10-29 | Traditional Chinese medicinal preparation for treating hyperostosis and preparation method of traditional Chinese medicinal preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105343463A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106110045A (en) * | 2016-08-29 | 2016-11-16 | 王富强 | A kind of Chinese medicine ointment treating hyperosteogeny |
-
2015
- 2015-10-29 CN CN201510723514.4A patent/CN105343463A/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106110045A (en) * | 2016-08-29 | 2016-11-16 | 王富强 | A kind of Chinese medicine ointment treating hyperosteogeny |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103385914A (en) | Hot compress salt and preparation method thereof | |
| CN104225508A (en) | Traditional Chinese medicine composition for cervical spondylosis treatment and preparation method thereof | |
| CN104083457A (en) | Orthopaedic medicinal liquor for treating qi deficiency and body weakness type lumbar muscle strain and preparation method | |
| CN101647878B (en) | Traditional Chinese medicine preparation for treating rheumatism and numbness | |
| CN103316141A (en) | Traditional Chinese medicine composition for treating cervical spondylosis | |
| CN105434795A (en) | Traditional Chinese medicine preparation containing folium artemisiae argyi and used for treating hyperostosis through external application | |
| CN105232905A (en) | Traditional Chinese medicine preparation for treating hyperostosis and preparing method of traditional Chinese medicine preparation | |
| CN104688966A (en) | Traditional Chinese medicine for treating orthopedic hyperosteogeny | |
| CN102552705B (en) | Traditional Chinese medicinal capsule for treating lumbar disc herniation and femoral head necrosis | |
| CN105287731A (en) | Externally-applied traditional Chinese medicine preparation for treating hyperostosis and preparation method thereof | |
| CN105343463A (en) | Traditional Chinese medicinal preparation for treating hyperostosis and preparation method of traditional Chinese medicinal preparation | |
| CN103417812A (en) | TCM composition for treatment of femoral head necrosis and preparation method thereof | |
| CN105688059A (en) | Traditional Chinese medicine preparation with folium artemisiae argyi for treating osteoproliferation through external application | |
| CN105288127A (en) | Pharmaceutical composition for treating hyperostosis and preparing method thereof | |
| CN104873699A (en) | Traditional Chinese medicine ointment and preparation method thereof | |
| CN104800443A (en) | Bone setting agent with functions of tonifying kidney and regenerating bone marrow | |
| CN104825993A (en) | Postoperative-care traditional Chinese medicine preparation and preparation method thereof for repair of ruptured achilles tendon | |
| CN112755134B (en) | Plaster for treating hyperosteogeny and preparation method thereof | |
| CN103272046A (en) | Traditional Chinese medicine for treating synovitis, bursitis and synovial plicaes effusion | |
| CN105213715A (en) | A kind of Chinese medicine preparation of curing hyperosteogeny for external application | |
| CN106138505B (en) | A kind of medicine for external application of osteoarthropathy that treating the initiation of wound sequelae | |
| CN105232906A (en) | Traditional Chinese medicinal preparation for treating hyperostosis through external application and preparation method of traditional Chinese medicinal preparation | |
| CN104689291A (en) | Traditional Chinese medicine preparation for facilitating lumbar disc herniation rehabilitation and preparation method | |
| CN105125860A (en) | Preparation for effectively treating osteoporosis | |
| CN104815146B (en) | Bone-knitting capsule |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20160224 |