CN105342614A - Standardized measurement method for region of interest of magnetic resonance image - Google Patents
Standardized measurement method for region of interest of magnetic resonance image Download PDFInfo
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Abstract
The invention relates to the technical field of application of nuclear magnetic resonance equipment and discloses a standardized measurement method for a region of interest of a magnetic resonance image. The method includes: designing a water phantom, and determining equal dividing and positioning marks on the inner wall of the water phantom; using the water phantom for magnetic resonance imaging to obtain a water phantom image; selecting the region of interest in the obtained water phantom image with the equal dividing and positioning marks. The standardized measurement method for the region of interest of the magnetic resonance image has the advantages that the objectiveness, flexibility and standardization in selection of the region of interest are realized, the water phantom is simple and convenient to operate, and unified management and statistical analysis of data are benefited.
Description
Technical field
The present invention relates to the applied technical field of nuclear magnetic resonance equipment, particularly relate to a kind of magnetic resonance image (MRI) region of interest Standardized Measuring Methods.
Background technology
Nuclear magnetic resonance is one of current most advanced medical imaging technology, highly sensitive to soft tissue, space orientation is accurate, "dead" and make it be better than CT, other image modes such as ultrasonic to human body without the feature of any damage.Clinician is screened out by magnetic resonance image (MRI) or investigates pathological changes, location, qualitative and quantitative analysis pathological changes, monitoring curative effect etc.Image doctor with shadow etc., thus draws diagnosis report with sick different shadow, different disease according to magnetic resonance image analysis.Therefore, the diagnoses and treatment of height to disease of magnetic resonance image (MRI) quality has and important meaning.
Magnetic resonance quality assurance (QualityAssurance, and quality control (QualityControl QA), QC) refer in the whole process of choosing, install, debug, running of magnetic resonance equipment, normalized operation is carried out in strict accordance with requiring, equipment indices and parameter are conformed with the regulations the technical requirement of standard, be in safety, accurate and effective duty, most optimally play the various performances of equipment, the systematic measures of qualitative picture is provided for diagnosing the illness.
Magnetic resonance quality assurance and quality control be clinical service at all, solve the various problems occurred in real work, its final purpose obtains the qualitative picture fully meeting diagnosis and require, namely refer to that magnetic resonance image (MRI) can provide enough information for Accurate Diagnosis, there is the feature such as high s/n ratio, high-contrast, high-resolution, accurately location, while image there is no artifact, distortion, uneven and fuzzy.Clinical Engineer carry out magnetic resonance periodically detecting and the primary evaluation of preventive maintenance according to being the signal to noise ratio of magnetic resonance image (MRI), the uniformity, thickness, two dimension distortion, spatial resolution and ghost etc.
At present, there is some problem in China's magnetic resonance quality control: (1) testing tool disunity, and each producer each model test water mould differs, and external water mould is expensive, not easily promotes.(2) test has very strong subjectivity, and manually choose ROI region of interest and lack unified standard, data affect by operator.This just in the urgent need to a set of for magnetic resonance quality control, the simple to operation and method of specification.
Summary of the invention
The present invention is for solving above-mentioned deficiency of the prior art, a kind of magnetic resonance image (MRI) region of interest Standardized Measuring Methods is proposed, its measuring method is objective, flexibly and specification selection standard allelopathic region of interest, be conducive to data unified management and statistical analysis, and water mould is simple and convenient.
For achieving the above object, the present invention is by the following technical solutions:
One aspect of the present invention, provides a kind of magnetic resonance image (MRI) region of interest markization measuring method, comprises the following steps:
Step 1: design water mould, at water mould inwall determination equal dividing and positioning labelling;
Step 2: utilize described water mould to carry out nuclear magnetic resonance, obtains the water mould image with equal dividing and positioning labelling;
Step 3: choose region of interest in the water mould image with equal dividing and positioning gauge point.
Further, in step 1, described at water mould inwall determination equal dividing and positioning labelling, concrete steps are, water mould inwall is provided with the locating dowel of decile, described locating dowel is vertically set on inwall, and the locating dowel (cross-wise direction of locating dowel) on horizontal cross-section of described decile forms the telltale mark point of decile.
Further, the locating dowel of described decile is at least 3.
Further, the locating dowel of described decile is 4.
Further, in step 2, the edge-occurrence of described water mould image has the equal dividing and positioning gauge point formed by described equal dividing and positioning post.
Further, described moisture film is cylinder water mould, spherical water mould or cube moisture film, or the structure of other shapes.
Further, for cylinder water mould or spherical water mould, in step 3, the described concrete steps choosing region of interest in the water mould image of equal dividing and positioning gauge point with its circumference in equal parts comprise:
Steps A 1: the equal dividing and positioning gauge point of connected symmetrical dendrimer, straight line intersection obtains image center;
Steps A 2: connect each equal dividing and positioning gauge point successively and obtain regular polygon;
Steps A 3: take image center as the center of circle, center is radius to the vertical dimension on a regular polygon limit, makes the inscribed circle of regular polygon, and this inscribed circle is selected region of interest.
Further, for cube water mould, in step 3, the described concrete steps choosing region of interest in the water mould image with equal dividing and positioning labelling comprise:
Step B1: the equal dividing and positioning gauge point of connected symmetrical dendrimer, straight line intersection obtains image center;
Step B2: connect each equal dividing and positioning gauge point successively and obtain regular polygon;
Step B3: take image center as the center of circle, center is radius to the vertical dimension on a regular polygon limit, makes the inscribed circle of regular polygon;
Step B4: the intersection point connecting adjacent positioned line and inscribed circle successively obtains a little regular polygon, and this little regular polygon is selected region of interest.
Further; for cylinder water mould or spherical water mould; when equal dividing and positioning post is 4; locating dowel decile is positioned at (Vertical Uniform is arranged on water mould inwall) on cylinder water mould inwall; or decile is positioned on the maximum horizontal tangent plane ball wall of spherical water mould; in step 3, the described concrete steps choosing region of interest in the water mould image with equal dividing and positioning gauge point comprise:
Steps A 1: the equal dividing and positioning gauge point of connected symmetrical dendrimer, straight line intersection obtains image center;
Steps A 2: connect each equal dividing and positioning gauge point successively and obtain square;
Steps A 3: take image center as the center of circle, center is radius to the vertical dimension on a square limit, and make the inscribed circle of regular polygon, this inscribed circle is selected region of interest.
Further, when equal dividing and positioning post is 4, for cube water mould, locating dowel is positioned on cubical four seamed edges, or be positioned on the axis of symmetry in cube four faces, in step 3, the described concrete steps choosing region of interest in the water mould image with equal dividing and positioning labelling comprise:
Step B1: the equal dividing and positioning gauge point of connected symmetrical dendrimer, straight line intersection obtains image center;
Step B2: connect each equal dividing and positioning gauge point successively and obtain square;
Step B3: take image center as the center of circle, center is radius to the vertical dimension on a regular polygon limit, makes the inscribed circle of regular polygon;
Step B4: the intersection point connecting adjacent positioned line and inscribed circle successively obtains a little square, and this little square is selected region of interest.
Another aspect of the present invention provides a kind of water mould, and the inwall of water mould is provided with the equal dividing and positioning post for determining equal dividing and positioning labelling.
Further, described moisture film is cylinder water mould, spherical water mould or cube moisture film.
The present invention adopts technique scheme, compared with prior art, has following technique effect:
Magnetic resonance image (MRI) region of interest Standardized Measuring Methods of the present invention, measuring method is objective, flexibly and specification selection standard allelopathic region of interest, be conducive to data unified management and statistical analysis; And water mould is simple and convenient, saves the processing time, adds precision; This measuring method is applicable to different testing tools, simple to operate; To contribute in medical research palpation really to break, the accuracy that its region of interest is located can be ensured.
Accompanying drawing explanation
Fig. 1 is the flow chart of a kind of magnetic resonance image (MRI) region of interest of the present invention Standardized Measuring Methods;
Fig. 2 is the region of interest schematic diagram of the measurement cylinder water mould using measuring method of the present invention, and wherein, 2a is cylinder water mould schematic diagram; 2b is that the region of interest of cylinder water mould chooses design sketch;
Fig. 3 is the region of interest schematic diagram of the measurement cube water mould using measuring method of the present invention, and wherein, 3a is cube water mould schematic diagram; 3b is that the region of interest of cube water mould chooses design sketch;
Wherein: wherein 1,2,3,4 is the locating dowel of cylinder water mould; 5 is the region of interest of cylinder water mould; 6,7,8,9 is the locating dowel of cube water mould, and 10 is the region of interest of cube water mould.
Detailed description of the invention
Carry out detailed and concrete introduction below by specific embodiment to the present invention, to make better to understand the present invention, but following embodiment does not limit the scope of the invention.
The MRI imaging system that the present embodiment adopts is SiemensMAGNETOMTrioTim3.0T magnetic resonance imaging system, and software version is VB15.
As shown in Figure 1, the invention provides a kind of magnetic resonance image (MRI) region of interest Standardized Measuring Methods, specifically comprise following three steps:
Step 1: design water mould, the telltale mark such as to determine at water mould inwall.Magnetic resonance image (MRI) water mould is designed to the structure of cylinder water mould, spherical water mould, cube water mould or other regular pattern composites, and arranges equal dividing and positioning labelling at water mould inwall, this decile telltale mark is four locating dowels that on water mould inwall, Vertical Uniform is arranged.
Step 2: utilize described water mould to carry out nuclear magnetic resonance, obtain water mould image.Wherein, the equal dividing and positioning gauge point of the locating dowel of labelling described in 1 formation in steps at the edge of the water mould image obtained.
Step 3: choose region of interest having in the water mould image of telltale mark point of obtaining.
Wherein, water mould inwall is provided with the locating dowel of decile, locating dowel is vertically set on water die wall, and the locating dowel of decile forms the telltale mark point of decile on the horizontal cross-section of locating dowel (or water mould).The edge-occurrence of the water mould image of magnetic resonance has the equal dividing and positioning gauge point formed by equal dividing and positioning post.
In actual applications, equal dividing and positioning post is at least 3, measuring method described above, and preferred equal dividing and positioning post is 4, and moisture film is the water mould of cylinder water mould, spherical water mould or cube moisture film or other planforms.Embodiment 1
Step 1, design cylinder water mould as shown in 2a in Fig. 2, water mould inwall has the locating dowel of four column type deciles, its circumference in equal parts.As 2b in Fig. 2, locating dowel 1, locating dowel 2, locating dowel 3, locating dowel 4.
Step 2, utilize described water mould to carry out nuclear magnetic resonance, obtain the water mould image with equal dividing and positioning gauge point.
Step 3, choose region of interest 5, as shown in 2b in Fig. 2 having in the magnetic resonance water mould image of equal dividing and positioning gauge point of obtaining;
Wherein, in step 3, the concrete setting up procedure choosing region of interest 5 in the cylinder magnetic resonance water mould image with equal dividing and positioning gauge point is as follows:
Steps A 1: utilize drawing instrument to connect four symmetrical equal dividing and positioning gauge points (from locating dowel 1, locating dowel 2, locating dowel 3 and locating dowel 4 horizontal cross-section formation) in magnetic resonance image (MRI), straight line intersection obtains image center and phantom image round dot.
Steps A 2: utilize drawing instrument to connect each equal dividing and positioning gauge point in magnetic resonance image (MRI) and obtain connecing square in circle.
Steps A 3: utilize drawing instrument to take image center as the center of circle in magnetic resonance image (MRI), image center is radius to the vertical dimension on a shape limit, square limit, makes the inscribed circle of square limit shape.This inscribed circle is selected region of interest 5.
After completing above-mentioned steps, obtain standardized magnetic resonance image (MRI) region of interest, magnetic resonance image (MRI) quality control can be carried out according to selected region of interest, evaluate the index such as signal to noise ratio, uniformity degree of image.
Embodiment 2
Step 1, design square water mould as shown in 3a in Fig. 3, water mould inwall has the locating dowel of four column type deciles, on square four seamed edges, as shown in 3b in Fig. 3, and locating dowel 6, locating dowel 7, locating dowel 8, locating dowel 9.
Step 2, utilize described water mould to carry out nuclear magnetic resonance, obtain the water mould image with equal dividing and positioning gauge point.
Step 3, in the magnetic resonance water mould image of the telltale mark points such as having of obtaining, choose region of interest 10, as 3b in Fig. 3.
Wherein, the concrete setting up procedure choosing region of interest 10 in the cube magnetic resonance water mould image with equal dividing and positioning gauge point is as follows:
Step B1: utilize in magnetic resonance image (MRI) drawing instrument connect four symmetries have equal dividing and positioning gauge point equal dividing and positioning gauge point (from locating dowel 6, locating dowel 7, locating dowel 8 and locating dowel 9 horizontal cross-section formation), straight line intersection obtains image center and phantom image square center point.
Step B2: utilize drawing instrument to take image center as the center of circle in magnetic resonance image (MRI), image center is radius to the vertical dimension on a square limit, makes foursquare inscribed circle.
Step B3: the intersection point utilizing drawing instrument to connect adjacent positioned line and inscribed circle successively in magnetic resonance image (MRI) obtains a little square, for connecing square in inscribed circle, this little square is region of interest 10.
After completing above-mentioned steps, obtain standardized magnetic resonance image (MRI) region of interest, magnetic resonance image (MRI) quality control can be carried out according to selected region of interest, evaluate the index such as signal to noise ratio, uniformity degree of image.
The area-of-interest of this measuring method can obtain fully, meet the high-quality magnetic resonance image (MRI) of diagnosis requirement, this magnetic resonance image (MRI) has the feature such as high s/n ratio, high-contrast, high-resolution, accurately location, for clinicist's Accurate Diagnosis provides enough information.
Be described in detail specific embodiments of the invention above, but it is just as example, the present invention is not restricted to specific embodiment described above.To those skilled in the art, any equivalent modifications that the present invention is carried out and substituting also all among category of the present invention.Therefore, equalization conversion done without departing from the spirit and scope of the invention and amendment, all should contain within the scope of the invention.
Claims (10)
1. a magnetic resonance image (MRI) region of interest markization measuring method, is characterized in that, comprise the following steps:
Step 1: design water mould, at water mould inwall determination equal dividing and positioning labelling;
Step 2: utilize described water mould to carry out nuclear magnetic resonance, obtains the water mould image with equal dividing and positioning labelling;
Step 3: choose region of interest in the water mould image with equal dividing and positioning gauge point.
2. measuring method according to claim 1, is characterized in that, in step 1, described at water mould inwall determination equal dividing and positioning labelling, concrete steps are, water mould inwall is provided with the locating dowel of decile, and the locating dowel of described decile forms the telltale mark point of decile on horizontal cross-section.
3. measuring method according to claim 2, is characterized in that, the locating dowel of described decile is at least 3.
4. measuring method according to claim 3, is characterized in that, the locating dowel of described decile is 4.
5. measuring method according to claim 1, is characterized in that, in step 2, the edge-occurrence of described water mould image has the telltale mark point of the decile formed by described equal dividing and positioning post.
6. the measuring method according to any one of claim 1, is characterized in that, described moisture film is cylinder water mould, spherical water mould or cube moisture film.
7. measuring method according to claim 6, is characterized in that, for cylinder water mould or spherical water mould, in step 3, the described concrete steps choosing region of interest in the water mould image with equal dividing and positioning gauge point comprise:
Steps A 1: the equal dividing and positioning gauge point of connected symmetrical dendrimer, straight line intersection obtains image center;
Steps A 2: connect each equal dividing and positioning gauge point successively and obtain regular polygon;
Steps A 3: take image center as the center of circle, center is radius to the vertical dimension on a regular polygon limit, makes the inscribed circle of regular polygon, and this inscribed circle is selected region of interest.
8. measuring method according to claim 6, is characterized in that, for cube water mould, in step 3, the described concrete steps choosing region of interest in the water mould image with equal dividing and positioning labelling comprise:
Step B1: the equal dividing and positioning gauge point of connected symmetrical dendrimer, straight line intersection obtains image center;
Step B2: connect each equal dividing and positioning gauge point successively and obtain regular polygon;
Step B3: take image center as the center of circle, center is radius to the vertical dimension on a regular polygon limit, makes the inscribed circle of regular polygon;
Step B4: the intersection point connecting adjacent positioned line and inscribed circle successively obtains a little regular polygon, and this little regular polygon is selected region of interest.
9. the water mould of measuring method as described in any one of claim 1-8, it is characterized in that, described water mould inwall is provided with the equal dividing and positioning post for determining equal dividing and positioning labelling.
10. a kind of water mould according to claim 9, is characterized in that, described moisture film is cylinder water mould, spherical water mould or cube moisture film.
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Citations (6)
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| US4922915A (en) * | 1987-11-27 | 1990-05-08 | Ben A. Arnold | Automated image detail localization method |
| CN1725029A (en) * | 2004-07-20 | 2006-01-25 | 北京大学第三医院 | The apparatus and method that are used for correcting deforming of diffusion image |
| US7056019B1 (en) * | 2002-10-22 | 2006-06-06 | Todd Hanson | Quality assurance phantom system |
| CN101991416A (en) * | 2009-08-20 | 2011-03-30 | 株式会社东芝 | Magnetic resonance imaging apparatus and RF coil unit |
| CN102478650A (en) * | 2010-11-29 | 2012-05-30 | 邱建峰 | Small-sized desktop type magnetic resonance quality control and comprehensive test phantom |
| CN203591259U (en) * | 2013-09-24 | 2014-05-14 | 西门子(深圳)磁共振有限公司 | Die body of magnetic resonance imaging system |
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4922915A (en) * | 1987-11-27 | 1990-05-08 | Ben A. Arnold | Automated image detail localization method |
| US7056019B1 (en) * | 2002-10-22 | 2006-06-06 | Todd Hanson | Quality assurance phantom system |
| CN1725029A (en) * | 2004-07-20 | 2006-01-25 | 北京大学第三医院 | The apparatus and method that are used for correcting deforming of diffusion image |
| CN101991416A (en) * | 2009-08-20 | 2011-03-30 | 株式会社东芝 | Magnetic resonance imaging apparatus and RF coil unit |
| CN102478650A (en) * | 2010-11-29 | 2012-05-30 | 邱建峰 | Small-sized desktop type magnetic resonance quality control and comprehensive test phantom |
| CN203591259U (en) * | 2013-09-24 | 2014-05-14 | 西门子(深圳)磁共振有限公司 | Die body of magnetic resonance imaging system |
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