CN105342614B - A kind of magnetic resonance image region of interest Standardized Measuring Methods - Google Patents
A kind of magnetic resonance image region of interest Standardized Measuring Methods Download PDFInfo
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Abstract
The present invention relates to the applied technical fields of nuclear magnetic resonance equipment, disclose a kind of magnetic resonance image region of interest Standardized Measuring Methods, comprising: design water mould determines equal dividing and positioning label in water mould inner wall；Magnetic resonance imaging is carried out using the water mould, obtains water mould image；Region of interest is chosen in the obtained water mould image with equal dividing and positioning mark point.Magnetic resonance image region of interest Standardized Measuring Methods of the invention are objective, flexibly and specification ground selection standard allelopathic region of interest, and water mould is simple, easy to operate, are conducive to data unified management and statistical analysis.
Description
Technical field
The present invention relates to the applied technical field of nuclear magnetic resonance equipment more particularly to a kind of magnetic resonance image region of interest marks
Standardization measurement method.
Background technique
Magnetic resonance imaging is one of current most advanced medical imaging technology, to soft tissue high sensitivity, space orientation it is accurate,
It is "dead" and make it better than other image modes such as CT, ultrasound without the characteristics of any damage human body.Clinician passes through magnetic
Resonance image screens out or checks lesion, positioning, qualitative and quantitative analysis lesion, monitoring curative effect etc..Image doctor is according to magnetic resonance figure
As analyzing with the different shadow of disease, different disease with shadow etc., to obtain diagnosis report.Therefore, the height of magnetic resonance image quality is to disease
Diagnoses and treatment has and its important meaning.
Magnetic resonance quality assurance (Quality Assurance, QA) and quality control (Quality Control, QC) refer to
Be in magnetic resonance equipment during the entire process of choosing, install, debug, run, in strict accordance with requiring to carry out normalized operation,
So that equipment indices and parameter is met the technical requirements of required standard, is in safe and accurate, effective working condition, it is optimal
Change the various performances that ground plays equipment, provides the systematic measures of qualitative picture to diagnose the illness.
Magnetic resonance quality assurance and quality control are clinical service at all, and what is occurred in solution real work various asks
Topic, final purpose are to obtain sufficiently to meet the qualitative picture that diagnosis requires, that is, refer to that magnetic resonance image can be Accurate Diagnosis
There is provided enough information, have the characteristics that high s/n ratio, high contrast, high-resolution, accurate positioning, while image do not have artifact,
It deforms, is uneven and fuzzy.Clinical Engineer magnetic resonance is periodically detected and the primary evaluation of preventive maintenance according to
According to signal-to-noise ratio, the uniformity, thickness, two dimension distortion, spatial resolution and the ghost etc. for being magnetic resonance image.
Currently, there are some problems: (1) testing tool disunity for the control of China's magnetic resonance quality, each each model of producer is surveyed
It is different to try water mould, external water mould is expensive, is not easy to promote.(2) test has very strong subjectivity, chooses ROI region of interest manually
Lack unified standard, data are influenced by operator.Just there is an urgent need to a set of for the control of magnetic resonance quality, simple to operation for this
And the method standardized.
Summary of the invention
To solve above-mentioned deficiency of the prior art of the present invention proposes a kind of magnetic resonance image region of interest standardization measurement
Method, measurement method is objective, flexibly and specification selection standard allelopathic region of interest, is conducive to data unified management and statistical
Analysis, and water mould is simple and convenient.
To achieve the above object, the invention adopts the following technical scheme:
One aspect of the present invention provides a kind of magnetic resonance image region of interest markization measurement method, including following step
It is rapid:
Step 1: design water mould determines that equal dividing and positioning marks in water mould inner wall；
Step 2: carrying out magnetic resonance imaging using the water mould, obtain the water mould image that there is equal dividing and positioning to mark；
Step 3: choosing region of interest in the water mould image with equal dividing and positioning mark point.
Further, in step 1, described to determine that equal dividing and positioning marks in water mould inner wall, the specific steps are in water mould inner wall
Be equipped with the positioning column of equal part, the positioning column is vertically set on inner wall, the positioning column of the equal part on horizontal cross-section (from
From the point of view of in the cross-wise direction of positioning column) formed equal part telltale mark point.
Further, the positioning column of the equal part is at least 3.
Further, the positioning column of the equal part is 4.
Further, in step 2, the edge-occurrence of the water mould image has the equal part formed by the equal dividing and positioning column to determine
Position mark point.
Further, the moisture film is the structure of cylindrical body water mould, spherical water mould or cube moisture film or other shapes.
Further, for cylindrical body water mould or spherical water mould, in step 3, it is described with its circumference in equal parts etc.
The specific steps that region of interest is chosen in the water mould image of point telltale mark point include:
Step A1: the equal dividing and positioning mark point of connected symmetrical dendrimer, straight line intersection obtain image center；
Step A2: it is sequentially connected each equal dividing and positioning mark point and obtains regular polygon；
Step A3: using image center as the center of circle, the vertical range at center to regular polygon a line is radius, is made just more
The inscribed circle of side shape, this inscribed circle are selected region of interest.
Further, in step 3, described in the water mould image marked with equal dividing and positioning for cube water mould
Choose region of interest specific steps include:
Step B1: the equal dividing and positioning mark point of connected symmetrical dendrimer, straight line intersection obtain image center；
Step B2: it is sequentially connected each equal dividing and positioning mark point and obtains regular polygon；
Step B3: using image center as the center of circle, the vertical range at center to regular polygon a line is radius, is made just more
The inscribed circle of side shape；
Step B4: the intersection point for being sequentially connected adjacent positioned line and inscribed circle obtains a small regular polygon, this is small just polygon
Shape is selected region of interest.
Further, for cylindrical body water mould or spherical water mould, when equal dividing and positioning column is 4, the quartiles such as positioning column
It is located at the maximum horizontal section of spherical water mould in (the vertical uniform setting on water mould inner wall) on cylindrical body water mould inner wall or equal part
On ball wall, in step 3, the specific steps packet that region of interest is chosen in the water mould image with equal dividing and positioning mark point
It includes:
Step A1: the equal dividing and positioning mark point of connected symmetrical dendrimer, straight line intersection obtain image center；
Step A2: it is sequentially connected each equal dividing and positioning mark point and obtains square；
Step A3: using image center as the center of circle, the vertical range of center to square a line is radius, is made just polygon
The inscribed circle of shape, this inscribed circle are selected region of interest.
Further, when equal dividing and positioning column is 4, for cube water mould, positioning column is located at four ribs of cube
Bian Shang, or on the axis of symmetry in four faces of cube, it is in step 3, described in the water mould figure marked with equal dividing and positioning
The specific steps of selection region of interest include: as in
Step B1: the equal dividing and positioning mark point of connected symmetrical dendrimer, straight line intersection obtain image center；
Step B2: it is sequentially connected each equal dividing and positioning mark point and obtains square；
Step B3: using image center as the center of circle, the vertical range at center to regular polygon a line is radius, is made just more
The inscribed circle of side shape；
Step B4: the intersection point for being sequentially connected adjacent positioned line and inscribed circle obtains a small square, this small square is
Selected region of interest.
Another aspect of the present invention provides a kind of water mould, and the inner wall of water mould is equipped with for determining equal dividing and positioning label
Equal dividing and positioning column.
Further, the moisture film is cylindrical body water mould, spherical water mould or cube moisture film.
The present invention by adopting the above technical scheme, compared with prior art, has the following technical effect that
Magnetic resonance image region of interest Standardized Measuring Methods of the invention, measurement method is objective, flexible and specification is chosen
Region of interest is standardized, data unified management and statistical analysis are conducive to；And water mould is simple and convenient, saves the processing time,
Increase precision；The measurement method is suitable for different testing tools, easy to operate；Facilitate diagnosis really in medical research
It is disconnected, it is ensured that the accuracy of its region of interest positioning.
Detailed description of the invention
Fig. 1 is a kind of flow chart of magnetic resonance image region of interest Standardized Measuring Methods of the present invention；
Fig. 2 is the region of interest schematic diagram using the measurement cylindrical body water mould of measurement method of the present invention, wherein 2a is cylinder
Body water mould schematic diagram；2b is that the region of interest of cylindrical body water mould chooses effect picture；
Fig. 3 is the region of interest schematic diagram using the measurement cube water mould of measurement method of the present invention, wherein 3a is cube
Body water mould schematic diagram；3b is that the region of interest of cube water mould chooses effect picture；
Wherein: wherein 1,2,3,4 be cylindrical body water mould positioning column；5 be the region of interest of cylindrical body water mould；6,7,8,9
It is the region of interest of cube water mould for the positioning column of cube water mould, 10.
Specific embodiment
The present invention is described in more detail below by specific embodiment, for a better understanding of the present invention,
But following embodiments are not intended to limit the scope of the invention.
The MRI imaging system that the present embodiment uses is Siemens MAGNETOM Trio Tim 3.0T magnetic resonance imaging system
System, software version VB15.
As shown in Figure 1, the present invention provides a kind of magnetic resonance image region of interest Standardized Measuring Methods, specifically include following
Three steps:
Step 1: design water mould determines in water mould inner wall and waits telltale marks.Magnetic resonance image is designed as justifying with water mould
The structure of cylinder water mould, spherical water mould, cube water mould or other regular pattern composites, and marked in water mould inner wall setting equal dividing and positioning,
Four piece positioning columns of the equal dividing and positioning labeled as vertical uniform setting on water mould inner wall.
Step 2: carrying out magnetic resonance imaging using the water mould, obtain water mould image.Wherein, in obtained water mould image
The equal dividing and positioning mark point that edge has label positioning column described in step 1 to be formed.
Step 3: choosing region of interest in the obtained water mould image with telltale mark point.
Wherein, the positioning column of equal part is equipped on water mould inner wall, positioning column is vertically set on water die wall, the positioning of equal part
Column forms the telltale mark point of equal part on the horizontal cross-section of positioning column (or water mould).The edge-occurrence of the water mould image of magnetic resonance
There is the equal dividing and positioning mark point formed by equal dividing and positioning column.
In practical applications, equal dividing and positioning column is at least 3, such as above-mentioned measurement method, and preferred equal dividing and positioning column is 4
A, moisture film is the water mould of cylindrical body water mould, spherical water mould or cube moisture film or other structures shape.Embodiment 1
Step 1, design cylindrical body water mould as shown in 2a in Fig. 2, the positioning column for cylindrical type equal part that there are four water mould inner walls,
Circumference in equal parts.Such as 2b in Fig. 2, positioning column 1, positioning column 2, positioning column 3, positioning column 4.
Step 2 carries out magnetic resonance imaging using the water mould, obtains the water mould image with equal dividing and positioning mark point.
Step 3 chooses region of interest 5 in the obtained magnetic resonance water mould image with equal dividing and positioning mark point, such as Fig. 2
Shown in middle 2b；
Wherein, in step 3, it is emerging that sense is chosen in the cylindrical body magnetic resonance water mould image with equal dividing and positioning mark point
The specific setting up procedure in interesting area 5 is as follows:
Step A1: four symmetrical equal dividing and positioning mark points are connected (from positioning using drawing tool in magnetic resonance image
See on column 1,4 horizontal cross-section of positioning column 2, positioning column 3 and positioning column and to be formed), straight line intersection obtains image center, that is, body mould
Image dot.
Step A2: in magnetic resonance image using drawing tool connect each equal dividing and positioning mark point obtain circle it is inscribed just
It is rectangular.
Step A3: using drawing tool using image center as the center of circle in magnetic resonance image, image center to pros
The vertical range of side shape a line is radius, makees the inscribed circle of square side shape.This inscribed circle is selected region of interest 5.
After completing above-mentioned steps, standardized magnetic resonance image region of interest is obtained, it can be according to selected region of interest
Carry out the control of magnetic resonance image quality, the indexs such as evaluation signal-to-noise ratio, uniformity degree of image.
Embodiment 2
Step 1, design square water mould as shown in 3a in Fig. 3, the positioning column for cylindrical type equal part that there are four water mould inner walls,
On four seamed edges of square, as shown in 3b in Fig. 3, positioning column 6, positioning column 7, positioning column 8, positioning column 9.
Step 2 carries out magnetic resonance imaging using the water mould, obtains the water mould image with equal dividing and positioning mark point.
Step 3, obtain have etc. telltale marks point magnetic resonance water mould image in choose region of interest 10, such as Fig. 3
Middle 3b.
Wherein, region of interest 10 is chosen in the cube magnetic resonance water mould image with equal dividing and positioning mark point
Specific setting up procedure is as follows:
Step B1: in magnetic resonance image using drawing tool connect four it is symmetrical with equal dividing and positioning mark point etc.
Divide telltale mark point (being formed from positioning column 6,9 horizontal cross-section of positioning column 7, positioning column 8 and positioning column), straight line intersection obtains
Obtain image center, that is, phantom image square center point.
Step B2: using drawing tool using image center as the center of circle in magnetic resonance image, image center to pros
The vertical range of shape a line is radius, makees the inscribed circle of square.
Step B3: it is obtained in magnetic resonance image using the intersection point that drawing tool is sequentially connected adjacent positioned line and inscribed circle
One small square is the inscribed square of inscribed circle, this small square is region of interest 10.
After completing above-mentioned steps, standardized magnetic resonance image region of interest is obtained, it can be according to selected region of interest
Carry out the control of magnetic resonance image quality, the indexs such as evaluation signal-to-noise ratio, uniformity degree of image.
The area-of-interest of the measurement method can obtain the high-quality magnetic resonance image for adequately, meeting diagnosis requirement, should
Magnetic resonance image has the characteristics that high s/n ratio, high contrast, high-resolution, accurate positioning, mentions for clinician's Accurate Diagnosis
For enough information.
Specific embodiments of the present invention are described in detail above, but it is merely an example, the present invention is simultaneously unlimited
It is formed on particular embodiments described above.To those skilled in the art, any couple of present invention carries out equivalent modifications and
Substitution is also all among scope of the invention.Therefore, without departing from the spirit and scope of the invention made by equal transformation and
Modification, all should be contained within the scope of the invention.
Claims (4)
1. a kind of magnetic resonance image region of interest markization measurement method, which comprises the following steps:
Step 1: design water mould determines that equal dividing and positioning marks in water mould inner wall；
Step 2: carrying out magnetic resonance imaging using the water mould, obtain the water mould image that there is equal dividing and positioning to mark, the water mould
The edge-occurrence of image has the telltale mark point that the equal part formed is marked by the equal dividing and positioning；
Step 3: choosing region of interest in the water mould image with equal dividing and positioning mark point；
The water mould is cylindrical body water mould, spherical water mould or cube water mould；
It is described to be selected in the water mould image with equal dividing and positioning mark point in step 3 for cylindrical body water mould or spherical water mould
The specific steps for taking region of interest include:
Step A1: the equal dividing and positioning mark point of connected symmetrical dendrimer, straight line intersection obtain image center；
Step A2: it is sequentially connected each equal dividing and positioning mark point and obtains regular polygon；
Step A3: using image center as the center of circle, the vertical range at center to regular polygon a line is radius, makees regular polygon
Inscribed circle, this inscribed circle is selected region of interest；
It is in step 3, described that region of interest is chosen in the water mould image marked with equal dividing and positioning for cube water mould
Specific steps include:
Step B1: the equal dividing and positioning mark point of connected symmetrical dendrimer, straight line intersection obtain image center；
Step B2: it is sequentially connected each equal dividing and positioning mark point and obtains regular polygon；
Step B3: using image center as the center of circle, the vertical range at center to regular polygon a line is radius, makees regular polygon
Inscribed circle；
Step B4: the intersection point for being sequentially connected adjacent positioned line and inscribed circle obtains a small regular polygon, this small regular polygon is
Selected region of interest.
2. measurement method according to claim 1, which is characterized in that described to determine that equal part is fixed in water mould inner wall in step 1
Position label, the specific steps are be equipped with the positioning column of equal part, the positioning column of equal part shape on horizontal cross-section on water mould inner wall
At the telltale mark point of equal part.
3. measurement method according to claim 2, which is characterized in that the positioning column of the equal part is at least 3.
4. measurement method according to claim 3, which is characterized in that the positioning column of the equal part is 4.
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| US4922915A (en) * | 1987-11-27 | 1990-05-08 | Ben A. Arnold | Automated image detail localization method |
| CN1725029A (en) * | 2004-07-20 | 2006-01-25 | 北京大学第三医院 | The apparatus and method that are used for correcting deforming of diffusion image |
| US7056019B1 (en) * | 2002-10-22 | 2006-06-06 | Todd Hanson | Quality assurance phantom system |
| CN101991416A (en) * | 2009-08-20 | 2011-03-30 | 株式会社东芝 | Magnetic resonance imaging apparatus and RF coil unit |
| CN102478650A (en) * | 2010-11-29 | 2012-05-30 | 邱建峰 | Small-sized desktop type magnetic resonance quality control and comprehensive test phantom |
| CN203591259U (en) * | 2013-09-24 | 2014-05-14 | 西门子(深圳)磁共振有限公司 | Die body of magnetic resonance imaging system |
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2015
- 2015-10-19 CN CN201510679969.0A patent/CN105342614B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4922915A (en) * | 1987-11-27 | 1990-05-08 | Ben A. Arnold | Automated image detail localization method |
| US7056019B1 (en) * | 2002-10-22 | 2006-06-06 | Todd Hanson | Quality assurance phantom system |
| CN1725029A (en) * | 2004-07-20 | 2006-01-25 | 北京大学第三医院 | The apparatus and method that are used for correcting deforming of diffusion image |
| CN101991416A (en) * | 2009-08-20 | 2011-03-30 | 株式会社东芝 | Magnetic resonance imaging apparatus and RF coil unit |
| CN102478650A (en) * | 2010-11-29 | 2012-05-30 | 邱建峰 | Small-sized desktop type magnetic resonance quality control and comprehensive test phantom |
| CN203591259U (en) * | 2013-09-24 | 2014-05-14 | 西门子(深圳)磁共振有限公司 | Die body of magnetic resonance imaging system |
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